quinolinic acid has been researched along with Acute Kidney Injury in 2 studies
Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.
Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nicotinamide adenine dinucleotide (NAD+) levels decline in experimental models of acute kidney injury (AKI)." | 4.31 | Hepatocyte nuclear factor 4α mediated quinolinate phosphoribosylltransferase (QPRT) expression in the kidney facilitates resilience against acute kidney injury. ( Ciampa, EJ; Clark, AJ; Etzrodt, V; Flores, BM; Huang, H; Parikh, SM; Saade, MC; Takakura, A; Vemireddy, V; Vu, KQ; Zandi-Nejad, K; Zsengellér, ZK, 2023) |
| "The biosynthetic routes leading to de novo nicotinamide adenine dinucleotide (NAD+) production are involved in acute kidney injury (AKI), with a critical role for quinolinate phosphoribosyl transferase (QPRT), a bottleneck enzyme of de novo NAD+ biosynthesis." | 4.12 | Cell stress response impairs de novo NAD+ biosynthesis in the kidney. ( Anglicheau, D; Bignon, Y; Cippà, PE; Fohlen, B; Galichon, P; Hertig, A; Karras, A; Lenoir, O; Nadour, Z; Naesens, M; Nemazanyy, I; Pallet, N; Poindessous, V; Rinaldi, A; Weill-Raynal, P, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bignon, Y | 1 |
| Rinaldi, A | 1 |
| Nadour, Z | 1 |
| Poindessous, V | 1 |
| Nemazanyy, I | 1 |
| Lenoir, O | 1 |
| Fohlen, B | 1 |
| Weill-Raynal, P | 1 |
| Hertig, A | 1 |
| Karras, A | 1 |
| Galichon, P | 1 |
| Naesens, M | 1 |
| Anglicheau, D | 1 |
| Cippà, PE | 1 |
| Pallet, N | 1 |
| Clark, AJ | 1 |
| Saade, MC | 1 |
| Vemireddy, V | 1 |
| Vu, KQ | 1 |
| Flores, BM | 1 |
| Etzrodt, V | 1 |
| Ciampa, EJ | 1 |
| Huang, H | 1 |
| Takakura, A | 1 |
| Zandi-Nejad, K | 1 |
| Zsengellér, ZK | 1 |
| Parikh, SM | 1 |
2 other studies available for quinolinic acid and Acute Kidney Injury
| Article | Year |
|---|---|
Cell stress response impairs de novo NAD+ biosynthesis in the kidney.
Topics: Acute Kidney Injury; Animals; Cell Line; Endoplasmic Reticulum Stress; Kidney; Male; Mice; Mice, Inb | 2022 |
Hepatocyte nuclear factor 4α mediated quinolinate phosphoribosylltransferase (QPRT) expression in the kidney facilitates resilience against acute kidney injury.
Topics: Acute Kidney Injury; Animals; Hepatocyte Nuclear Factors; Kidney; Mice; NAD; Peroxisome Proliferator | 2023 |