quinolinic acid has been researched along with Acquired Metabolic Diseases, Brain in 5 studies
Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glutaric acidemia type I is an inherited metabolic disorder caused by a severe deficiency of the mitochondrial glutaryl-CoA dehydrogenase activity leading to accumulation of predominantly glutaric and 3-hydroxyglutaric acids in the brain tissue of the affected patients." | 1.34 | Evidence for a synergistic action of glutaric and 3-hydroxyglutaric acids disturbing rat brain energy metabolism. ( Ceolato, PC; Dutra-Filho, CS; Ferreira, GC; Latini, A; Perry, ML; Schuck, PF; Tonin, A; Vargas, CR; Viegas, CM; Wajner, M; Wannmacher, CM; Wyse, AT, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barbieri Caus, L | 1 |
| Pasquetti, MV | 1 |
| Seminotti, B | 3 |
| Woontner, M | 1 |
| Wajner, M | 4 |
| Calcagnotto, ME | 1 |
| Amaral, AU | 1 |
| da Silva, JC | 1 |
| de Oliveira, FH | 1 |
| Ribeiro, RT | 1 |
| Vargas, CR | 2 |
| Leipnitz, G | 2 |
| Santamaría, A | 2 |
| Souza, DO | 2 |
| Colín-González, AL | 1 |
| Paz-Loyola, AL | 1 |
| Serratos, I | 1 |
| Ribeiro, CA | 1 |
| Ferreira, GC | 1 |
| Tonin, A | 1 |
| Schuck, PF | 1 |
| Viegas, CM | 1 |
| Ceolato, PC | 1 |
| Latini, A | 1 |
| Perry, ML | 1 |
| Wyse, AT | 1 |
| Dutra-Filho, CS | 1 |
| Wannmacher, CM | 1 |
| Heyes, MP | 1 |
| Papagapiou, M | 1 |
| Leonard, C | 1 |
| Markey, SP | 1 |
| Auer, RN | 1 |
5 other studies available for quinolinic acid and Acquired Metabolic Diseases, Brain
| Article | Year |
|---|---|
Increased susceptibility to quinolinic acid-induced seizures and long-term changes in brain oscillations in an animal model of glutaric acidemia type I.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain; Brain Diseases, Metabolic; Disease Models, Ani | 2022 |
Induction of Neuroinflammatory Response and Histopathological Alterations Caused by Quinolinic Acid Administration in the Striatum of Glutaryl-CoA Dehydrogenase Deficient Mice.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases, Metabolic; CD3 Complex; Corpus Striat | 2018 |
Toxic synergism between quinolinic acid and organic acids accumulating in glutaric acidemia type I and in disorders of propionate metabolism in rat brain synaptosomes: Relevance for metabolic acidemias.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain; Brain Diseases, Metabolic; Disease Models, Ani | 2015 |
Evidence for a synergistic action of glutaric and 3-hydroxyglutaric acids disturbing rat brain energy metabolism.
Topics: Animals; Antioxidants; Brain; Brain Chemistry; Brain Diseases, Metabolic; Creatine Kinase; Drug Syne | 2007 |
Effects of profound insulin-induced hypoglycemia on quinolinic acid in hippocampus and plasma.
Topics: Animals; Brain Chemistry; Brain Diseases, Metabolic; Dialysis; Electroencephalography; Extracellular | 1991 |