quinine has been researched along with Tuberculosis--Multidrug-Resistant* in 1 studies
1 other study(ies) available for quinine and Tuberculosis--Multidrug-Resistant
| Article | Year |
|---|---|
Synthesis and in vitro antitubercular activity of a series of quinoline derivatives.
A series of 33 quinoline derivatives have been synthesized and evaluated for their in vitro antibacterial activity against Mycobacterium tuberculosis H(37)Rv using the Alamar Blue susceptibility test and the activity expressed as the minimum inhibitory concentration (MIC) in microg/mL. Compounds 5e and 5f exhibited a significant activity at 6.25 and 3.12 microg/mL, respectively, when compared with first line drugs such as ethambutol and could be a good starting point to develop new lead compounds in the fight against multi-drug resistant tuberculosis. Topics: Antitubercular Agents; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Quinolines; Structure-Activity Relationship; Tuberculosis, Multidrug-Resistant | 2009 |