Page last updated: 2024-08-17

quinidine and Dysarthria, Pseudobulbar

quinidine has been researched along with Dysarthria, Pseudobulbar in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (40.00)29.6817
2010's12 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davis, C; Formella, AE; Hammond, FM; Ledon, F; Sauve, W1
Fralick, M; Kesselheim, AS; Sacks, CA1
Casselman, J; Patatanian, E1
Appel, SH; Formella, AE; Lomen-Hoerth, C; Pattee, GL; Pope, LE; Wymer, JP1
Cutler, AJ; D'Amico, S; Davis, CS; Doody, RS; Ledon, F; Shin, P; Siffert, J; Yonan, C1
Roman, MW1
Alexander, DN; Cutler, AJ; D'Amico, S; Davis, CS; Doody, RS; Formella, AE; Hammond, FM; Ledon, F; Sauve, W; Shin, P; Siffert, J; Yonan, C; Zorowitz, RD1
Stahl, SM1
Reiman, AT; Schrader, JV; Wahler, RG1
Sauvé, WM1
Rosen, H1
Haiman, G; Miller, A; Pratt, H1
Miller, A; Pratt, H; Schiffer, RB1
Appel, SH; Berg, JE; Bradley, WG; Brooks, BR; Olney, RK; Pope, LE; Smith, RA; Thisted, RA1
Brooks, BR; Smith, RA1
Hingorani, VN; Kittrelle, JP1
Weintraub, D1
Pope, LE; Schiffer, R1
Miller, A; Panitch, H1

Reviews

6 review(s) available for quinidine and Dysarthria, Pseudobulbar

ArticleYear
Dextromethorphan/quinidine for the treatment of pseudobulbar affect.
    The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists, 2014, Volume: 29, Issue:4

    Topics: Clinical Trials as Topic; Crying; Dextromethorphan; Drug Combinations; Excitatory Amino Acid Antagonists; Humans; Laughter; Pseudobulbar Palsy; Quinidine; Receptors, sigma; Sigma-1 Receptor; Treatment Outcome

2014
Recognizing and treating pseudobulbar affect.
    CNS spectrums, 2016, Volume: 21, Issue:S1

    Topics: Dextromethorphan; Drug Combinations; Early Diagnosis; Excitatory Amino Acid Antagonists; Humans; Pseudobulbar Palsy; Quinidine

2016
Dextromethorphan/quinidine sulfate for pseudobulbar affect.
    Drugs of today (Barcelona, Spain : 1998), 2008, Volume: 44, Issue:9

    Topics: Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Dextromethorphan; Drug Combinations; Humans; Pseudobulbar Palsy; Quinidine; Selective Serotonin Reuptake Inhibitors

2008
Pseudobulbar affect: the spectrum of clinical presentations, etiologies and treatments.
    Expert review of neurotherapeutics, 2011, Volume: 11, Issue:7

    Topics: Adrenergic alpha-Antagonists; Brain; Clinical Trials as Topic; Crying; Dextromethorphan; Excitatory Amino Acid Antagonists; Humans; Laughter; Pseudobulbar Palsy; Quinidine; Synaptic Transmission

2011
Review of pseudobulbar affect including a novel and potential therapy.
    The Journal of neuropsychiatry and clinical neurosciences, 2005,Fall, Volume: 17, Issue:4

    Topics: Analgesics, Non-Narcotic; Cytochrome P-450 CYP2D6 Inhibitors; Dextromethorphan; Drug Therapy, Combination; Humans; Mood Disorders; Pseudobulbar Palsy; Quinidine

2005
Therapeutic use of dextromethorphan: key learnings from treatment of pseudobulbar affect.
    Journal of the neurological sciences, 2007, Aug-15, Volume: 259, Issue:1-2

    Topics: Animals; Brain; Dextromethorphan; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Humans; Multiple Sclerosis; Pseudobulbar Palsy; Quinidine

2007

Trials

4 trial(s) available for quinidine and Dysarthria, Pseudobulbar

ArticleYear
Safety, Tolerability, and Effectiveness of Dextromethorphan/Quinidine for Pseudobulbar Affect Among Study Participants With Traumatic Brain Injury: Results From the PRISM-II Open Label Study.
    PM & R : the journal of injury, function, and rehabilitation, 2018, Volume: 10, Issue:10

    Topics: Adult; Brain Injuries, Traumatic; Dextromethorphan; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Injury Severity Score; Male; Maximum Tolerated Dose; Middle Aged; Neuropsychological Tests; Patient Safety; Patient Selection; Prognosis; Prospective Studies; Pseudobulbar Palsy; Quinidine; Risk Assessment; Severity of Illness Index; Treatment Outcome

2018
An open-label multicenter study to assess the safety of dextromethorphan/quinidine in patients with pseudobulbar affect associated with a range of underlying neurological conditions.
    Current medical research and opinion, 2014, Volume: 30, Issue:11

    Topics: Adolescent; Adult; Affective Symptoms; Aged; Aged, 80 and over; Cohort Studies; Crying; Cytochrome P-450 CYP2D6 Inhibitors; Dextromethorphan; Drug Combinations; Excitatory Amino Acid Antagonists; Female; Humans; Laughter; Male; Middle Aged; Pseudobulbar Palsy; Quinidine; Treatment Outcome; Young Adult

2014
PRISM II: an open-label study to assess effectiveness of dextromethorphan/quinidine for pseudobulbar affect in patients with dementia, stroke or traumatic brain injury.
    BMC neurology, 2016, Jun-09, Volume: 16

    Topics: Aged; Brain Injuries, Traumatic; Dementia; Dextromethorphan; Drug Administration Schedule; Drug Combinations; Excitatory Amino Acid Antagonists; Female; Humans; Male; Middle Aged; Pseudobulbar Palsy; Quinidine; Severity of Illness Index; Stroke; Treatment Outcome

2016
Treatment of pseudobulbar affect in ALS with dextromethorphan/quinidine: a randomized trial.
    Neurology, 2004, Oct-26, Volume: 63, Issue:8

    Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Dextromethorphan; Double-Blind Method; Drug Combinations; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Male; Metabolic Clearance Rate; Middle Aged; Pseudobulbar Palsy; Quinidine; Receptors, N-Methyl-D-Aspartate; Treatment Outcome

2004

Other Studies

10 other study(ies) available for quinidine and Dysarthria, Pseudobulbar

ArticleYear
Assessment of Use of Combined Dextromethorphan and Quinidine in Patients With Dementia or Parkinson Disease After US Food and Drug Administration Approval for Pseudobulbar Affect.
    JAMA internal medicine, 2019, 02-01, Volume: 179, Issue:2

    Topics: Aged; Amyotrophic Lateral Sclerosis; Dementia; Dextromethorphan; Drug Combinations; Excitatory Amino Acid Antagonists; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Parkinson Disease; Pseudobulbar Palsy; Quinidine; United States; United States Food and Drug Administration

2019
An open-label study to assess safety, tolerability, and effectiveness of dextromethorphan/quinidine for pseudobulbar affect in dementia: PRISM II results.
    CNS spectrums, 2016, Volume: 21, Issue:6

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Dementia; Dementia, Vascular; Dextromethorphan; Diarrhea; Drug Combinations; Excitatory Amino Acid Antagonists; Female; Frontotemporal Dementia; Headache; Humans; Lewy Body Disease; Male; Middle Aged; Pseudobulbar Palsy; Quinidine; Urinary Tract Infections

2016
NueDexta: A Treatment for Pseudobulbar Affect.
    Issues in mental health nursing, 2015, Volume: 36, Issue:12

    Topics: Affective Symptoms; Dextromethorphan; Drug Combinations; Excitatory Amino Acid Antagonists; Humans; Pseudobulbar Palsy; Quinidine

2015
Dextromethorphan-quinidine-responsive pseudobulbar affect (PBA): psychopharmacological model for wide-ranging disorders of emotional expression?
    CNS spectrums, 2016, Volume: 21, Issue:6

    Topics: Dextromethorphan; Drug Combinations; Emotions; Excitatory Amino Acid Antagonists; Humans; Models, Theoretical; Pseudobulbar Palsy; Psychopharmacology; Quinidine; Receptors, Glutamate; Receptors, Serotonin; Receptors, sigma

2016
Use of Compounded Dextromethorphan-Quinidine Suspension for Pseudobulbar Affect in Hospice Patients.
    Journal of palliative medicine, 2017, Volume: 20, Issue:3

    Topics: Aged, 80 and over; Crying; Dextromethorphan; Drug Combinations; Female; Hospice Care; Humans; Laughter; Male; Medical Audit; Pseudobulbar Palsy; Quinidine; Retrospective Studies; Treatment Outcome

2017
Effects of dextromethorphan/quinidine on auditory event-related potentials in multiple sclerosis patients with pseudobulbar affect.
    Journal of clinical psychopharmacology, 2009, Volume: 29, Issue:5

    Topics: Acoustic Stimulation; Adult; Dextromethorphan; Evoked Potentials, Auditory; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Pseudobulbar Palsy; Psychomotor Performance; Quinidine

2009
Dextromethorphan/quinidine (Nuedexta) for pseudobulbar affect.
    The Medical letter on drugs and therapeutics, 2011, Jun-13, Volume: 53, Issue:1366

    Topics: Dextromethorphan; Drug Combinations; Drug Interactions; Humans; Pseudobulbar Palsy; Quinidine

2011
Treatment of pseudobulbar affect in ALS.
    The Lancet. Neurology, 2005, Volume: 4, Issue:5

    Topics: Amyotrophic Lateral Sclerosis; Animals; Brain Chemistry; Dextromethorphan; Disease Models, Animal; Drug Combinations; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Humans; Pseudobulbar Palsy; Quinidine; Serotonin

2005
Treatment of pseudobulbar affect in ALS: October 26 highlight and commentary.
    Neurology, 2005, May-24, Volume: 64, Issue:10

    Topics: Amyotrophic Lateral Sclerosis; Antitussive Agents; Clinical Trials as Topic; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Drug Combinations; Drug Resistance; Drug Synergism; Enzyme Inhibitors; Genetic Testing; Genotype; Humans; Pseudobulbar Palsy; Quinidine

2005
Therapeutic options for emotional lability: current and emerging treatments.
    The American journal of geriatric pharmacotherapy, 2005, Volume: 3 Suppl A

    Topics: Antidepressive Agents; Dextromethorphan; Drug Interactions; Humans; Mood Disorders; Pseudobulbar Palsy; Quinidine; Randomized Controlled Trials as Topic

2005