Page last updated: 2024-08-17

quinidine and Disease Models, Animal

quinidine has been researched along with Disease Models, Animal in 72 studies

Research

Studies (72)

Timeframe	Studies, this research(%)	All Research%
pre-1990	26 (36.11)	18.7374
1990's	9 (12.50)	18.2507
2000's	18 (25.00)	29.6817
2010's	15 (20.83)	24.3611
2020's	4 (5.56)	2.80

Authors

Authors	Studies
Baizman, ER; Becker, C; Bell, RH; Birsner, NC; Bohnet, EA; Busacca, CA; Carabateas, PM; Chadwick, CC; Gruett, MD; Johnson, RE	1
Chen, X; Chong, CR; Liu, JO; Shi, L; Sullivan, DJ	1
Bajda, M; Brus, B; Czerwińska, P; Filipek, B; Gobec, S; Malawska, B; Sałat, K; Więckowska, A; Więckowski, K	1
Bracke, ME; De Ryck, T; Katritzky, AR; Patronov, A; Roman, BI; Slavov, SH; Stevens, CV; Vanhoecke, BW	1
Aljayyoussi, G; Amewu, RK; Angulo-Barturén, I; Bazaga, SF; Belén, M; Biagini, GA; Campo, B; Charman, SA; Chen, G; Davies, J; Martínez, MS; Nixon, GL; O' Neill, PM; Roberts, NL; Ryan, E; Sabbani, S; Shackleford, DM; Sharma, R; Shore, ER; Stocks, PA; Ward, SA	1
Guo, HF; Jin, J; Li, ZR; Liu, ZY; Xie, ZS; Xue, ST; Yi, H; Zhang, L	1
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV	1
Chen, LZ; Huang, X; Liu, MM; Liu, XH; Ma, D; Shi, JB; Shu, HY; Wu, J; Yu, YL	1
Lin, T; Lv, S; Mi, L; Pan, X; Song, J; Tian, F; Wan, Y; Wang, Y; Wu, Z	1
Hamlin, RL; Kijtawornrat, A; Limprasutr, V; Meedech, P; Saengklub, N	1
Behrends, JC; Bode, C; Bodi, I; Brunner, M; Bugger, H; Doleschall, Z; Franke, G; Fürniss, H; Jolivet, G; Lang, CN; Menza, M; Mettke, L; Michaelides, K; Odening, KE; Pantulu, ND; Perez-Feliz, S; Peyronnet, R; Rieke, R; Ryan de Medeiros, A; Steinfurt, J; Zehender, M; Ziupa, D; Zur Hausen, A	1
Antzelevitch, C; Barajas-Martínez, H; Betzenhauser, M; Di Diego, JM; Hu, D; Minoura, Y; Nesterenko, VV; Panama, BK	1
de Lange, EC; Eriksson, J; Koepp, M; Labots, M; Lammertsma, AA; Potschka, H; Rongen, M; Russmann, V; Schuit, R; Seeger, N; Syvänen, S; van Kooij, R; Verbeek, J; Voskuyl, RA; Windhorst, AD; Zellinger, C	1
Antzelevitch, C; Gurabi, Z; Koncz, I; Nesterenko, VV; Patocskai, B	1
Gigout, S; Louvel, J; Pumain, R	1
Albrecht, M; Dombrowsky, H; Frerichs, I; Goldmann, T; Lautenschläger, I; Sarau, J; Uhlig, S; Weiler, N; Zitta, K	1
Matsumoto, RR; Nguyen, L	1
Antzelevitch, C; Belardinelli, L; Guo, D; Hackett, J; Jiao, Z; Li, H; Shryock, JC; Wu, L; Yan, GX	1
Dautova, Y; Grace, AA; Huang, CL; Sabir, I; Zhang, Y	1
Jacobson, G; Sleigh, JW; Steyn-Ross, A; Steyn-Ross, M; Voss, LJ	1
Antzelevitch, C; Burashnikov, A; Nof, E	1
Lazzara, R	1
Dautova, Y; Grace, AA; Huang, CL; Zhang, Y	1
Lacroix, P	1
Dong, QX; Gao, JM; He, JH; Huang, CJ; Li, CQ; Xu, YQ; Xuan, YX; Yu, HP; Zhu, JJ	1
Dukes-Mcewan, J	1
Bauskin, A; Breit, S; Bursill, J; Campbell, T; Singarayar, S; Vandenberg, J; Wu, W; Wyse, K	1
Brooks, BR; Smith, RA	1
Abe, J; Hamada, Y; Harada, T; Hashimoto, K; Horii, I; Sawada, Y; Shiotani, M	1
Lirussi, F; Pussard, E	1
Colledge, WH; Goddard, CA; Grace, AA; Huang, CL; Stokoe, KS; Thomas, G	1
Morita, H; Morita, ST; Wu, J; Zipes, DP	1
Balasubramaniam, R; Colledge, WH; Goddard, CA; Grace, AA; Huang, CL; Stokoe, KS	1
Borggrefe, M; Breithardt, G; Eckardt, L; Milberg, P; Osada, N; Schimpf, R; Tegelkamp, R; Wolpert, C	1
Kaufman, ES	1
Goddard, CA; Grace, AA; Huang, CL; Jones, VJ; Li, LM; Sabir, IN	1
Inoue, H; Mashima, S; Matsuo, H; Murao, S	1
Banitt, EH; Kvam, DC; Schmid, JR	1
Carlson, GP; Fossa, AA	1
Bergey, JL; McCallum, JD; Nocella, K	1
Hernández, J; Serrano, JS	1
Haruna, M; Kimoto, S; Nakao, T; Ueda, M	1
Huang, JD; Leu, BL	1
Gautam, CS; Pandhi, P; Sharma, PL	1
Cha, Y; Feld, GK; Sawhney, N; Shahrokni, S; Wales, A; Wolf, P	1
Cheymol, G; Chézalviel-Guilbert, F; Davy, JM; Deplanne, V; Poirier, JM; Weissenburger, J; Xia, YZ	1
Allessie, MA; Dorland, R; Wijffels, MC	1
Imai, R; Tamura, T; Yamamoto, K; Yamamoto, M	1
Hsiao, CL; Huang, JD; Kan, WM; Kuo, JH; Liu, YT; Shieh, CY; Su, SF	1
Buntenkötter, S	1
Elharrar, V; Gaum, WE; Zipes, DP	1
Billingham, M; Binetti, G; Harrison, DC; Kernoff, R; Markiewicz, W	1
Butterfield, JL; D'Alonzo, AJ; Drexler, AP; Sergio, SL	1
Isaksson, M; Ljunggren, B	1
Bertilsson, L; Kaneko, S; Otani, K	1
Boyden, P; Danilo, P; Leichter, D; Rosen, MR; Rosen, TS	1
Coker, SJ	1
Balazs, T; Ehrreich, SJ; el-Hage, AN; Johnson, GL	1
Inoue, H; Mashima, S; Matsuo, H; Murao, S; Sugimoto, T	1
Inoue, H; Mashima, S; Matsuo, H; Nozaki, A; Sugimoto, T; Toda, I	1
Inoue, H; Matsuo, H; Nozaki, A; Sugimoto, T; Toda, I	1
Kaverina, NV; Senova, ZP; Ul'iànova, OV; Vikxliàev, IuI	1
Faust, G; Fiedler, W	1
Clark, WW; Pearson, RD; Stebbins, WC; Weiland, NG	1
Marmo, E	1
Gorodinskaia, VIa	1
Bhargava, KP; Kohli, RP; Shamsi, MA; Sinha, JN	1
Okuma, M	1
Vrbovský, L	2
Damato, AN; Paulay, KL; Weisfogel, GM	1
Baum, T; Eckfeld, DK; Rowles, G; Shropshire, AT; Varner, LL	1

Reviews

4 review(s) available for quinidine and Disease Models, Animal

Article	Year
Quinidine in short QT syndrome: an old drug for a new disease. Journal of cardiovascular electrophysiology, 2007, Volume: 18, Issue:6 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Electrocardiography; Electrophysiologic Techniques, Cardiac; Flecainide; Genetic Predisposition to Disease; Humans; Quinidine; Rabbits; Sotalol; Treatment Outcome	2007
[Compounds with antiarrhythmic effects]. Die Pharmazie, 1973, Volume: 28, Issue:6 Topics: Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Animals, Laboratory; Anti-Arrhythmia Agents; Antidepressive Agents; Antimalarials; Arrhythmias, Cardiac; Chemical Phenomena; Chemistry; Disease Models, Animal; Histamine H1 Antagonists; Lidocaine; Procainamide; Quinidine; Structure-Activity Relationship	1973
[Combined effect of beta-adrenoblockaders with other pharmacologic agents (review of the literature)]. Vrachebnoe delo, 1971, Volume: 7 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia, Inhalation; Angina Pectoris; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmias, Cardiac; Atropine; Cardiac Glycosides; Cardiovascular Diseases; Disease Models, Animal; Diuretics; Drug Synergism; Ethyl Ethers; Halothane; Heart Failure; Humans; Parasympatholytics; Phentolamine; Pheochromocytoma; Potassium Chloride; Quinidine; Sympatholytics; Vasodilator Agents	1971
[Thrombopenia]. Nihon rinsho. Japanese journal of clinical medicine, 1972, Volume: 30, Issue:1 Topics: Animals; Antibodies; Blood Platelets; Disease Models, Animal; Dogs; Freund's Adjuvant; Guinea Pigs; Methods; Phospholipids; Quinidine; Rabbits; Rats; Thrombocytopenia	1972

Other Studies

68 other study(ies) available for quinidine and Disease Models, Animal

Article	Year
4,5-Dihydro-1-phenyl-1H-2,4-benzodiazepines: novel antiarrhythmic agents. Journal of medicinal chemistry, 1993, Oct-29, Volume: 36, Issue:22 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzodiazepines; Cats; Disease Models, Animal; Dogs; Guinea Pigs; Heart Ventricles; Male; Myocardial Contraction; Myocardial Infarction; Potassium Channels; Rats; Rats, Sprague-Dawley; Refractory Period, Electrophysiological; Sodium Channels; Structure-Activity Relationship	1993
A clinical drug library screen identifies astemizole as an antimalarial agent. Nature chemical biology, 2006, Volume: 2, Issue:8 Topics: Animals; Antimalarials; Astemizole; Chloroquine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Resistance; Drug Resistance, Multiple; Humans; Mice; Plasmodium falciparum; Plasmodium yoelii	2006
Synthesis of new N-benzylpiperidine derivatives as cholinesterase inhibitors with β-amyloid anti-aggregation properties and beneficial effects on memory in vivo. Bioorganic & medicinal chemistry, 2015, May-15, Volume: 23, Issue:10 Topics: Acetylcholinesterase; Alzheimer Disease; Amnesia; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Disease Models, Animal; Donepezil; Humans; Indans; Indoles; Male; Memory; Mice; Models, Molecular; Neuroprotective Agents; Phthalimides; Piperidines; Protein Aggregates; Scopolamine; Structure-Activity Relationship	2015
4-Fluoro-3',4',5'-trimethoxychalcone as a new anti-invasive agent. From discovery to initial validation in an in vivo metastasis model. European journal of medicinal chemistry, 2015, Aug-28, Volume: 101 Topics: Animals; Antineoplastic Agents, Phytogenic; Biological Products; Cell Line, Tumor; Cell Movement; Cell Survival; Chalcones; Chick Embryo; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Discovery; Female; Humans; Mice; Mice, Nude; Molecular Structure; Myocardium; Neoplasm Invasiveness; Neoplasm Metastasis; Quantitative Structure-Activity Relationship	2015
Synthesis and profiling of benzylmorpholine 1,2,4,5-tetraoxane analogue N205: Towards tetraoxane scaffolds with potential for single dose cure of malaria. Bioorganic & medicinal chemistry, 2018, 07-15, Volume: 26, Issue:11 Topics: Administration, Oral; Animals; Antimalarials; Disease Models, Animal; Drug Stability; Humans; Inhibitory Concentration 50; Malaria; Mice; Morpholines; Plasmodium falciparum; Rats; Tetraoxanes	2018
Substituted benzothiophene and benzofuran derivatives as a novel class of bone morphogenetic Protein-2 upregulators: Synthesis, anti-osteoporosis efficacies in ovariectomized rats and a zebrafish model, and ADME properties. European journal of medicinal chemistry, 2020, Aug-15, Volume: 200 Topics: Animals; Benzofurans; Bone Morphogenetic Protein 2; Caco-2 Cells; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Mice; Mice, Inbred BALB C; Molecular Structure; Osteoporosis; Ovariectomy; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thiophenes; Zebrafish	2020
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49 Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection	2020
Discovery and development of novel pyrimidine and pyrazolo/thieno-fused pyrimidine derivatives as potent and orally active inducible nitric oxide synthase dimerization inhibitor with efficacy for arthritis. European journal of medicinal chemistry, 2021, Mar-05, Volume: 213 Topics: Administration, Oral; Animals; Arthritis; Cells, Cultured; Dimerization; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Development; Enzyme Inhibitors; Freund's Adjuvant; Humans; Lipopolysaccharides; Male; Mice; Molecular Structure; Nitric Oxide; Nitric Oxide Synthase Type II; Pyrazoles; Pyrimidines; Rats; Rats, Sprague-Dawley; RAW 264.7 Cells; Structure-Activity Relationship	2021
Downregulating Gasdermin D Reduces Severe Acute Pancreatitis Associated with Pyroptosis. Medical science monitor : international medical journal of experimental and clinical research, 2021, Feb-14, Volume: 27 Topics: Acute Disease; Animals; Disease Models, Animal; Interleukin-18; Intestinal Mucosa; Intestines; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Pancreas; Pancreatitis; Phosphate-Binding Proteins; Pyroptosis; Quinidine; Tumor Necrosis Factor-alpha	2021
Characteristics of electromechanical window in anesthetized rabbit models of short QT and long QT syndromes. The Journal of toxicological sciences, 2017, Volume: 42, Issue:5 Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Benzopyrans; Biomarkers; Biomarkers, Pharmacological; Cromakalim; Disease Models, Animal; Electrocardiography; Isoflurane; Long QT Syndrome; Phenethylamines; Pinacidil; Quinidine; Rabbits; Risk; Sulfonamides; Systole; Torsades de Pointes; Ventricular Pressure	2017
Transgenic short-QT syndrome 1 rabbits mimic the human disease phenotype with QT/action potential duration shortening in the atria and ventricles and increased ventricular tachycardia/ventricular fibrillation inducibility. European heart journal, 2019, 03-07, Volume: 40, Issue:10 Topics: Action Potentials; Animals; Animals, Genetically Modified; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Electrocardiography; Female; Heart Atria; Heart Conduction System; Heart Defects, Congenital; Heart Ventricles; Humans; Male; Phenotype; Quinidine; Rabbits	2019
Effect of Wenxin Keli and quinidine to suppress arrhythmogenesis in an experimental model of Brugada syndrome. Heart rhythm, 2013, Volume: 10, Issue:7 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Brugada Syndrome; Disease Models, Animal; Dogs; Drugs, Chinese Herbal; Myocytes, Cardiac; Patch-Clamp Techniques; Quinidine	2013
[11C]quinidine and [11C]laniquidar PET imaging in a chronic rodent epilepsy model: impact of epilepsy and drug-responsiveness. Nuclear medicine and biology, 2013, Volume: 40, Issue:6 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzazepines; Carbon Radioisotopes; Chronic Disease; Disease Models, Animal; Epilepsy; Female; Gene Expression Regulation; Kinetics; Male; Phenobarbital; Positron-Emission Tomography; Quinidine; Quinolines; Radiochemistry; Rats; Rats, Sprague-Dawley; Recurrence; Treatment Outcome	2013
Cellular mechanism underlying hypothermia-induced ventricular tachycardia/ventricular fibrillation in the setting of early repolarization and the protective effect of quinidine, cilostazol, and milrinone. Circulation. Arrhythmia and electrophysiology, 2014, Volume: 7, Issue:1 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Cilostazol; Disease Models, Animal; Dogs; Electrocardiography; Heart Conduction System; Hypothermia, Induced; Milrinone; Perfusion; Phosphodiesterase 3 Inhibitors; Quinidine; Signal Transduction; Tachycardia, Ventricular; Tetrazoles; Time Factors; Ventricular Fibrillation	2014
Decrease of neocortical paired-pulse depression in GAERS and possible implication of gap junctions. Neuroscience letters, 2015, Jan-01, Volume: 584 Topics: Animals; Anticonvulsants; Carbenoxolone; Cerebral Cortex; Disease Models, Animal; Electric Stimulation; Epilepsy, Absence; Gap Junctions; In Vitro Techniques; Neocortex; Quinidine; Rats, Wistar; Species Specificity; Synaptic Transmission	2015
Quinidine, but not eicosanoid antagonists or dexamethasone, protect the gut from platelet activating factor-induced vasoconstriction, edema and paralysis. PloS one, 2015, Volume: 10, Issue:3 Topics: Animals; Dexamethasone; Disease Models, Animal; Edema; Eicosanoids; Female; Gastrointestinal Diseases; Intestinal Mucosa; Paralysis; Platelet Activating Factor; Protective Agents; Quinidine; Rats; Vasoconstriction	2015
Involvement of AMPA receptors in the antidepressant-like effects of dextromethorphan in mice. Behavioural brain research, 2015, Dec-15, Volume: 295 Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Depressive Disorder; Dextromethorphan; Disease Models, Animal; Excitatory Amino Acid Antagonists; Hindlimb Suspension; Imipramine; Ketamine; Male; Mice; Quinidine; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Swimming	2015
Role of late sodium current in modulating the proarrhythmic and antiarrhythmic effects of quinidine. Heart rhythm, 2008, Volume: 5, Issue:12 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart Ventricles; Myocytes, Cardiac; Quinidine; Rabbits; Sodium; Sodium Channels; Torsades de Pointes	2008
Atrial arrhythmogenesis in wild-type and Scn5a+/delta murine hearts modelling LQT3 syndrome. Pflugers Archiv : European journal of physiology, 2009, Volume: 458, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease Models, Animal; Flecainide; Heart Rate; Humans; Long QT Syndrome; Mice; Mice, Transgenic; NAV1.5 Voltage-Gated Sodium Channel; Quinidine; Sodium Channels; Treatment Outcome	2009
Excitatory effects of gap junction blockers on cerebral cortex seizure-like activity in rats and mice. Epilepsia, 2009, Volume: 50, Issue:8 Topics: Analgesics, Non-Narcotic; Animals; Carbenoxolone; Cerebral Cortex; Connexins; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Enzyme Inhibitors; Female; Gap Junction delta-2 Protein; In Vitro Techniques; Magnesium; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Quinidine; Quinine; Rats; Rats, Sprague-Dawley; Seizures; Time Factors	2009
Cellular basis for atrial fibrillation in an experimental model of short QT1: implications for a pharmacological approach to therapy. Heart rhythm, 2010, Volume: 7, Issue:2 Topics: Action Potentials; Analysis of Variance; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Chlorobenzenes; Disease Models, Animal; Dogs; Electrocardiography; Isoproterenol; Lidocaine; ortho-Aminobenzoates; Quinidine	2010
How the heart can fibrillate: when diversity is a disadvantage. Heart rhythm, 2010, Volume: 7, Issue:2 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Chlorobenzenes; Disease Models, Animal; Dogs; Humans; Lidocaine; ortho-Aminobenzoates; Quinidine	2010
Atrial arrhythmogenic properties in wild-type and Scn5a+/- murine hearts. Experimental physiology, 2010, Volume: 95, Issue:10 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Atrial Function; Brugada Syndrome; Cardiac Pacing, Artificial; Disease Models, Animal; Electrophysiologic Techniques, Cardiac; Flecainide; Heart Atria; Heart Ventricles; Mice; Mice, 129 Strain; Mice, Transgenic; NAV1.5 Voltage-Gated Sodium Channel; Perfusion; Quinidine; Sodium Channels; Time Factors; Ventricular Function	2010
Electrocardiographic toxicity in the guinea pig. Current protocols in pharmacology, 2002, Volume: Chapter 5 Topics: Amitriptyline; Anesthesia; Animals; Disease Models, Animal; Drug-Related Side Effects and Adverse Reactions; Electrocardiography; Guinea Pigs; Heart Arrest; Male; Papaverine; Quinidine; Specimen Handling	2002
Human cardiotoxic drugs delivered by soaking and microinjection induce cardiovascular toxicity in zebrafish. Journal of applied toxicology : JAT, 2014, Volume: 34, Issue:2 Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Cardiotoxins; Clomipramine; Cyclophosphamide; Disease Models, Animal; Edema; Gentamicins; Heart Diseases; Heart Rate; Heart Ventricles; Larva; Microinjections; Nimodipine; Pericardium; Quinidine; Terfenadine; Tetracycline; Toxicity Tests; Verapamil; Yolk Sac; Zebrafish	2014
Atrial fibrillation: onset and perpetuation. Veterinary journal (London, England : 1997), 2002, Volume: 164, Issue:2 Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease Models, Animal; Horse Diseases; Horses; Humans; Prevalence; Quinidine	2002
Extracellular acidosis modulates drug block of Kv4.3 currents by flecainide and quinidine. Journal of cardiovascular electrophysiology, 2003, Volume: 14, Issue:6 Topics: Acidosis; Animals; Anti-Arrhythmia Agents; Biological Transport, Active; Cricetinae; Cricetulus; Disease Models, Animal; Dose-Response Relationship, Drug; Electrophysiology; Female; Flecainide; Hydrogen-Ion Concentration; Ion Channel Gating; Membrane Potentials; Models, Cardiovascular; Ovary; Potassium Channels; Potassium Channels, Voltage-Gated; Quinidine; Sensitivity and Specificity; Shal Potassium Channels; Statistics as Topic; Time Factors	2003
Treatment of pseudobulbar affect in ALS. The Lancet. Neurology, 2005, Volume: 4, Issue:5 Topics: Amyotrophic Lateral Sclerosis; Animals; Brain Chemistry; Dextromethorphan; Disease Models, Animal; Drug Combinations; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Humans; Pseudobulbar Palsy; Quinidine; Serotonin	2005
Practical application of guinea pig telemetry system for QT evaluation. The Journal of toxicological sciences, 2005, Volume: 30, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Antipsychotic Agents; Bepridil; Cisapride; Disease Models, Animal; Electrocardiography; Guinea Pigs; Haloperidol; Heart; Humans; Injections, Intravenous; Long QT Syndrome; Male; Nifedipine; Pimozide; Piperidines; Pyridines; Quinidine; Reproducibility of Results; Telemetry; Terfenadine; Thioridazine	2005
Quinine distribution in pregnant mice with Plasmodium berghei malaria. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2006, Volume: 28, Issue:4 Topics: Animals; Antimalarials; Disease Models, Animal; Female; Fetus; Malaria; Mice; Placenta; Plasmodium berghei; Pregnancy; Pregnancy Complications, Parasitic; Quinidine	2006
Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/Delta murine hearts modelling long QT syndrome 3. The Journal of physiology, 2007, Jan-01, Volume: 578, Issue:Pt 1 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Disease Models, Animal; Electric Stimulation; Electrocardiography; Electrophysiology; Female; Flecainide; Heart; Heart Conduction System; In Vitro Techniques; Long QT Syndrome; Male; Mice; Mice, Transgenic; NAV1.5 Voltage-Gated Sodium Channel; Quinidine; Sodium Channels	2007
Differences in arrhythmogenicity between the canine right ventricular outflow tract and anteroinferior right ventricle in a model of Brugada syndrome. Heart rhythm, 2007, Volume: 4, Issue:1 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Brugada Syndrome; Disease Models, Animal; Dogs; Electrocardiography; Electrophysiologic Techniques, Cardiac; Heart Conduction System; Heart Ventricles; Male; Pinacidil; Quinidine; Ventricular Fibrillation; Ventricular Function, Right	2007
Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/- murine hearts modelling the Brugada syndrome. The Journal of physiology, 2007, May-15, Volume: 581, Issue:Pt 1 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Brugada Syndrome; Disease Models, Animal; Electric Stimulation; Electrophysiology; Female; Flecainide; Gene Expression Regulation; Heart; Male; Mice; Mice, Inbred Strains; NAV1.5 Voltage-Gated Sodium Channel; Quinidine; Sodium Channels	2007
Reduction of dispersion of repolarization and prolongation of postrepolarization refractoriness explain the antiarrhythmic effects of quinidine in a model of short QT syndrome. Journal of cardiovascular electrophysiology, 2007, Volume: 18, Issue:6 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Dose-Response Relationship, Drug; Electrocardiography; Electrophysiologic Techniques, Cardiac; Flecainide; Heart Conduction System; In Vitro Techniques; Pinacidil; Quinidine; Rabbits; Random Allocation; Refractory Period, Electrophysiological; Sotalol; Vasodilator Agents	2007
Criteria for arrhythmogenicity in genetically-modified Langendorff-perfused murine hearts modelling the congenital long QT syndrome type 3 and the Brugada syndrome. Pflugers Archiv : European journal of physiology, 2008, Volume: 455, Issue:4 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Brugada Syndrome; Cardiac Pacing, Artificial; Disease Models, Animal; Electrocardiography; Endocardium; Flecainide; Heart Rate; Long QT Syndrome; Mice; Mice, Transgenic; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Perfusion; Pericardium; Quinidine; Sodium Channels; Time Factors	2008
Effects of atrial pacing, isoprenaline and lignocaine on experimental polymorphous ventricular tachycardia. Cardiovascular research, 1984, Volume: 18, Issue:9 Topics: Animals; Blood Pressure; Cardiac Pacing, Artificial; Disease Models, Animal; Dogs; Electrocardiography; Female; Heart Atria; Heart Rate; Heart Ventricles; Isoproterenol; Lidocaine; Male; Quinidine; Tachycardia	1984
Antiarrhythmic and electrophysiologic actions of flecainide in animal models. The American journal of cardiology, 1984, Feb-27, Volume: 53, Issue:5 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Dogs; Electrophysiology; Flecainide; Heart Conduction System; In Vitro Techniques; Lidocaine; Piperidines; Procainamide; Quinidine; Rabbits	1984
Antiarrhythmic effect of disulfiram in various cardiotoxic models. Pharmacology, 1983, Volume: 26, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Disease Models, Animal; Disulfiram; Heart Diseases; Male; Myocardial Contraction; Ouabain; Quinidine; Rabbits; Rats; Rats, Inbred Strains	1983
Acute coronary artery occlusion-reperfusion-induced arrhythmias in rats, dogs and pigs: antiarrhythmic evaluation of quinidine, procainamide and lidocaine. European journal of pharmacology, 1982, Jul-09, Volume: 81, Issue:2 Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Coronary Disease; Disease Models, Animal; Dogs; Female; Heart Rate; Lidocaine; Male; Perfusion; Potassium; Procainamide; Quinidine; Rats; Rats, Inbred Strains; Species Specificity; Swine	1982
Experimental automaticity induced by mechanical lesion in rat isolated right ventricle: the effects of quinidine, phenytoin, and propranolol. Journal of pharmacological methods, 1982, Volume: 7, Issue:4 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Female; Male; Phenytoin; Propranolol; Quinidine; Rats; Rats, Inbred Strains; Ventricular Function	1982
[Effects of antiarrhythmic agents on ventricular arrhythmias following myocardial infarct induced with glass beads in dogs (author's transl)]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1981, Volume: 78, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Coronary Vessels; Disease Models, Animal; Dogs; Electrocardiography; Female; Glass; Injections, Intra-Arterial; Lidocaine; Male; Myocardial Infarction; Propranolol; Quinidine	1981
Inhibition of intestinal P-glycoprotein and effects on etoposide absorption. Cancer chemotherapy and pharmacology, 1995, Volume: 35, Issue:5 Topics: Adenylyl Imidodiphosphate; Animals; Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Etoposide; In Vitro Techniques; Infusions, Intravenous; Intestinal Absorption; Intestine, Small; Jejunum; Male; Microvilli; Quinidine; Rats; Rats, Sprague-Dawley	1995
Differential effect of selected antiarrhythmic drugs on coronary artery ligation-induced ventricular arrhythmias on the right or left sides. Methods and findings in experimental and clinical pharmacology, 1995, Volume: 17, Issue:5 Topics: Animals; Anti-Arrhythmia Agents; Coronary Disease; Disease Models, Animal; Dogs; Female; Ligation; Male; Propranolol; Quinidine; Sotalol; Tachycardia, Ventricular; Verapamil	1995
Electrophysiologic effects of the new class III antiarrhythmic drug dofetilide compared to the class IA antiarrhythmic drug quinidine in experimental canine atrial flutter: role of dispersion of refractoriness in antiarrhythmic efficacy. Journal of cardiovascular electrophysiology, 1996, Volume: 7, Issue:9 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Atrial Flutter; Disease Models, Animal; Dogs; Electrocardiography; Heart Conduction System; Phenethylamines; Quinidine; Sulfonamides; Treatment Outcome	1996
Combination of sotalol and quinidine in a canine model of torsades de pointes: no increase in the QT-related proarrhythmic action of sotalol. Journal of cardiovascular electrophysiology, 1998, Volume: 9, Issue:5 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Dogs; Drug Therapy, Combination; Electrophysiology; Infusions, Intravenous; Quinidine; Sodium Chloride; Sotalol; Torsades de Pointes	1998
Pharmacologic cardioversion of chronic atrial fibrillation in the goat by class IA, IC, and III drugs: a comparison between hydroquinidine, cibenzoline, flecainide, and d-sotalol. Journal of cardiovascular electrophysiology, 1999, Volume: 10, Issue:2 Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Chronic Disease; Disease Models, Animal; Electrocardiography; Flecainide; Follow-Up Studies; Goats; Heart Conduction System; Imidazoles; Injections, Intravenous; Quinidine; Secondary Prevention; Sotalol; Treatment Outcome	1999
Acute canine model for drug-induced Torsades de Pointes in drug safety evaluation-influences of anesthesia and validation with quinidine and astemizole. Toxicological sciences : an official journal of the Society of Toxicology, 2001, Volume: 60, Issue:1 Topics: Acute Disease; Anesthesia; Anesthetics, Inhalation; Animals; Astemizole; Atrioventricular Node; Catheter Ablation; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electric Stimulation; Electrocardiography; Female; Halothane; Heart Block; Isoflurane; Long QT Syndrome; Male; Pentobarbital; Quinidine; Sensitivity and Specificity; Torsades de Pointes	2001
Effect of hydroxyzine on the transport of etoposide in rat small intestine. Anti-cancer drugs, 2001, Volume: 12, Issue:3 Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Etoposide; Histamine H1 Antagonists; Hydroxyzine; In Vitro Techniques; Infusions, Intravenous; Intestinal Absorption; Intestine, Small; Jejunum; Male; Microvilli; Quinidine; Rats; Rats, Sprague-Dawley; Time Factors	2001
[Myocardial model arrhythmias and anti-arrhythmic principles]. DTW. Deutsche tierarztliche Wochenschrift, 1978, Jun-05, Volume: 85, Issue:6 Topics: Animals; Animals, Laboratory; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cell Membrane Permeability; Disease Models, Animal; Drug Evaluation, Preclinical; Quinidine; Stimulation, Chemical; Swine	1978
Effect of drugs on conduction delay and incidence of ventricular arrhythmias induced by acute coronary occlusion in dogs. The American journal of cardiology, 1977, Volume: 39, Issue:4 Topics: Animals; Aprindine; Arrhythmias, Cardiac; Coronary Disease; Disease Models, Animal; Dogs; Heart Conduction System; Indenes; Isoproterenol; Quinidine; Verapamil	1977
Problems in assessing infarction size by epicardial mapping: preliminary studies with quinidine. European journal of cardiology, 1976, Volume: 4, Issue:4 Topics: Animals; Disease Models, Animal; Dogs; Electrocardiography; Hemodynamics; Myocardial Infarction; Myocardium; Quinidine	1976
Comparison of the effects of intravenous LNC-834, a new antiarrhythmic agent, and quinidine in canine models of arrhythmia. Journal of cardiovascular pharmacology, 1990, Volume: 16, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Electrophysiology; Female; Hemodynamics; Hypotension; Male; Quinidine; Ventricular Fibrillation	1990
Ultraviolet B irradiation inhibits the induction of photoallergy to systemically administered quinidine in the mouse. Photodermatology, photoimmunology & photomedicine, 1991, Volume: 8, Issue:4 Topics: Animals; Cyclophosphamide; Disease Models, Animal; Dose-Response Relationship, Radiation; Female; Inflammation; Injections, Intraperitoneal; Mice; Photosensitivity Disorders; Quinidine; Skin; Ultraviolet Rays	1991
Studies on active transport of (E)-10-hydroxynortriptyline in the kidney and brain of rats: effects of propranolol and quinidine. Pharmacology & toxicology, 1991, Volume: 68, Issue:5 Topics: Animals; Biological Transport, Active; Brain; Disease Models, Animal; Kidney; Male; Metabolic Clearance Rate; Nortriptyline; Propranolol; Quinidine; Rats; Rats, Inbred Strains	1991
A canine model of torsades de pointes. Pacing and clinical electrophysiology : PACE, 1988, Volume: 11, Issue:12 Topics: Aconitine; Aconitum; Animals; Disease Models, Animal; Dogs; Electrocardiography; Electrodes, Implanted; Heart; Quinidine; Tachycardia	1988
Anesthetized rabbit as a model for ischemia- and reperfusion-induced arrhythmias: effects of quinidine and bretylium. Journal of pharmacological methods, 1989, Volume: 21, Issue:4 Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Bretylium Compounds; Coronary Disease; Coronary Vessels; Disease Models, Animal; Male; Myocardial Reperfusion; Myocardial Reperfusion Injury; Quinidine; Rabbits	1989
Effects of antiarrhythmic agents on isoproterenol-induced ventricular fibrillation in heavy rats: a possible model of sudden cardiac death. Research communications in chemical pathology and pharmacology, 1986, Volume: 51, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Body Weight; Bretylium Tosylate; Death, Sudden; Disease Models, Animal; Electrocardiography; Isoproterenol; Male; Niacin; Phenytoin; Procainamide; Propranolol; Quaternary Ammonium Compounds; Quinidine; Rats; Ventricular Fibrillation; Verapamil	1986
Ventricular fibrillation threshold in canine hearts with quinidine induced prolonged QT interval: effects of atrial pacing, isoproterenol, and lignocaine. Cardiovascular research, 1986, Volume: 20, Issue:5 Topics: Animals; Cardiac Pacing, Artificial; Disease Models, Animal; Dogs; Female; Heart; Isoproterenol; Lidocaine; Male; Quinidine; Tachycardia; Ventricular Fibrillation	1986
Inhomogeneity of ventricular refractory period in canine heart with quinidine-induced long QT interval: a comparative study on effects of heart rate, isoprenaline, and lignocaine. Cardiovascular research, 1985, Volume: 19, Issue:10 Topics: Animals; Disease Models, Animal; Dogs; Electric Stimulation; Female; Heart; Heart Rate; Isoproterenol; Lidocaine; Male; Quinidine; Tachycardia	1985
Effects of bretylium tosylate on inhomogeneity of refractoriness and ventricular fibrillation threshold in canine hearts with quinidine-induced long QT interval. Cardiovascular research, 1985, Volume: 19, Issue:10 Topics: Animals; Blood Pressure; Bretylium Compounds; Bretylium Tosylate; Disease Models, Animal; Dogs; Female; Heart; Male; Quinidine; Tachycardia; Ventricular Fibrillation	1985
[Antiarrhythimic properties of ethmozine]. Farmakologiia i toksikologiia, 1970, Volume: 33, Issue:6 Topics: Aconitum; Animals; Anti-Arrhythmia Agents; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiac Complexes, Premature; Cats; Coronary Vessels; Depression, Chemical; Disease Models, Animal; Dogs; Electric Stimulation; Electrocardiography; Heart Rate; Humans; Ligation; Procainamide; Quinidine; Rats; Stimulation, Chemical; Tachycardia, Paroxysmal; Time Factors	1970
Noise-and drug-induced hearing loss in monkeys. Advances in oto-rhino-laryngology, 1973, Volume: 20 Topics: Acoustic Stimulation; Animals; Auditory Threshold; Conditioning, Operant; Deafness; Disease Models, Animal; Haplorhini; Hearing Loss, Noise-Induced; Kanamycin; Macaca; Methods; Neomycin; Papio; Quinidine; Sodium Salicylate; Time Factors	1973
Effects of different drugs with beta-adrenolytic activity on experimental models of arrhythmias. Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1971, Volume: 269, Issue:2 Topics: Aconitum; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Asphyxia; Barium; Calcium Chloride; Cats; Chlorides; Chloroform; Disease Models, Animal; Electrocardiography; Epinephrine; Guinea Pigs; Magnesium; Male; Potassium; Quinidine; Rats; Sodium Chloride; Strophanthins; Sympatholytics; Vasopressins	1971
Centrogenic cardiac arrhythmia induced by aconitine: a new "model" for screening of anti-arrhythmic drugs. Japanese journal of pharmacology, 1971, Volume: 21, Issue:6 Topics: Adrenergic beta-Antagonists; Alkaloids; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Coronary Vessels; Disease Models, Animal; Dogs; Electrocardiography; Epinephrine; Female; Ligation; Male; Phenytoin; Procainamide; Propranolol; Quinidine	1971
[Comparison of the effect of various antiarrhythmic drugs on the model of experimental epinephrine arrhythmia]. Bratislavske lekarske listy, 1973, Volume: 60, Issue:2 Topics: Amides; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cats; Disease Models, Animal; Dogs; Epinephrine; Ethylamines; Female; Male; Phenanthrenes; Procainamide; Quinidine	1973
Sinus nodal reentry. Effect of quinidine. The American journal of cardiology, 1974, May-06, Volume: 33, Issue:5 Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Disease Models, Animal; Dogs; Electrocardiography; Heart Conduction System; Pacemaker, Artificial; Quinidine; Tachycardia	1974
Observations on models used for the evaluation of antiarrhythmic drugs. Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 193, Issue:1 Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Atropine; Benzazepines; Bretylium Compounds; Chlorpheniramine; Diazepam; Disease Models, Animal; Dogs; Drug Antagonism; Guinea Pigs; Imipramine; Ketones; Lidocaine; Male; Meperidine; Mephentermine; Ouabain; Phentolamine; Phenytoin; Procainamide; Promazine; Promethazine; Propranolol; Quinidine	1971
[Relative effectiveness of various antiarrhythmia drugs in experimental aconitine arrhythmia]. Bratislavske lekarske listy, 1971, Volume: 56, Issue:6 Topics: Aconitum; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Blood Pressure; Disease Models, Animal; Dogs; Female; Male; Procainamide; Quinidine	1971