quinidine has been researched along with Breast Neoplasms in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.26) | 18.7374 |
| 1990's | 10 (52.63) | 18.2507 |
| 2000's | 5 (26.32) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (15.79) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, M; Qin, Q; Sun, Y; Wang, J; Wang, L; Wu, T; Xue, Y; Yang, H; Yin, W; Zhao, D | 1 |
| Barrow, D; Eissa, AG; Foster, PA; Gee, J; Powell, LE; Simons, C | 1 |
| Anderson, MS; Bertz, R; Bhardwaj, R; Collins, JL; Coric, V; Croop, R; Finley, JA; Madonia, J; Stock, DA; Stringfellow, J | 1 |
| McCracken, MA; Strobl, JS; Zhou, Q | 1 |
| Martirosyan, AR; Melkoumian, ZK; Strobl, JS | 1 |
| Borowiec, AS; Gouilleux, F; Guénin, S; Guerineau, F; Hague, F; Harir, N; Lassoued, K; Ouadid-Ahidouch, H; Roudbaraki, M | 1 |
| Strobl, JS; Wonderlin, WF; Woodfork, KA | 1 |
| Mross, K | 1 |
| Peterson, VA; Strobl, JS; Wonderlin, WF; Woodfork, KA | 1 |
| Bissett, D; Habeshaw, T; Harnett, A; Jodrell, D; Kerr, DJ; Leonard, RC; Macham, MA; Paul, J; Soukop, M; Wishart, GC | 1 |
| Cather, C; Davidson, AG; Melkoumian, Z; Strobl, JS; Wang, S; Wonderlin, WF; Woodfork, KA | 1 |
| Klimatcheva, E; Wonderlin, WF | 1 |
| Davie, JR; Lucktong, A; Melkoumian, ZK; Moniwa, M; Strobl, JS; Zhou, Q | 1 |
| Guo, Z; Wang, X; Zhu, A | 1 |
| Donehower, RC; Grochow, LB; Hendricks, CB; Kaufmann, SH; Rowinsky, EK | 1 |
| Hamilton, TG; Kaye, SB; Morrison, JG; Plumb, JA; Wishart, GC | 1 |
| Cook, DI; Wegman, EA; Young, JA | 1 |
| Harnett, AN; Jones, RD; Kaye, SB; Kerr, DJ; Rankin, EM; Ray, S | 1 |
| Assaraf, YG; Molina, A; Schimke, RT | 1 |
2 trial(s) available for quinidine and Breast Neoplasms
| Article | Year |
|---|---|
P-Glycoprotein and Breast Cancer Resistance Protein Transporter Inhibition by Cyclosporine and Quinidine on the Pharmacokinetics of Oral Rimegepant in Healthy Subjects.
Topics: ATP Binding Cassette Transporter, Subfamily B; Breast Neoplasms; Cross-Over Studies; Cyclosporine; Female; Healthy Volunteers; Humans; Membrane Transport Proteins; Neoplasm Proteins; Piperidines; Pyridines; Quinidine | 2022 |
Quinidine as a resistance modulator of epirubicin in advanced breast cancer: mature results of a placebo-controlled randomized trial.
Topics: Adult; Aged; Breast Neoplasms; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Epirubicin; Female; Humans; Middle Aged; Proportional Hazards Models; Quinidine; Remission Induction; Scotland; Survival Rate | 1994 |
17 other study(ies) available for quinidine and Breast Neoplasms
| Article | Year |
|---|---|
Design, synthesis, and biological evaluation of novel pyrazolo [3,4-d]pyrimidine derivatives as potent PLK4 inhibitors for the treatment of TRIM37-amplified breast cancer.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Screening Assays, Antitumor; Female; Humans; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrimidines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Tripartite Motif Proteins; Ubiquitin-Protein Ligases | 2022 |
4th generation nonsteroidal aromatase inhibitors: An iterative SAR-guided design, synthesis, and biological evaluation towards picomolar dual binding inhibitors.
Topics: Aromatase; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Receptors, Estrogen; Triazoles | 2022 |
Control of mammary tumor cell growth in vitro by novel cell differentiation and apoptosis agents.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Differentiation; Cell Division; Chloroquine; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Humans; In Vitro Techniques; Intercalating Agents; Ki-67 Antigen; Molecular Structure; Quinidine; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2002 |
Myc protein is differentially sensitive to quinidine in tumor versus immortalized breast epithelial cell lines.
Topics: Breast; Breast Neoplasms; Cell Cycle Proteins; Cell Differentiation; Cell Division; DNA-Binding Proteins; E2F Transcription Factors; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Humans; Oligonucleotides, Antisense; Phosphorylation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-myc; Quinidine; Retinoblastoma Protein; RNA, Messenger; S Phase; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 2002 |
IGF-1 activates hEAG K(+) channels through an Akt-dependent signaling pathway in breast cancer cells: role in cell proliferation.
Topics: Androstadienes; Astemizole; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Ether-A-Go-Go Potassium Channels; Female; Humans; Insulin-Like Growth Factor I; Ion Channel Gating; Membrane Potentials; Mitogen-Activated Protein Kinases; Phenolsulfonphthalein; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Potassium; Potassium Channel Blockers; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinidine; RNA Interference; RNA, Messenger; RNA, Small Interfering; Serum; Signal Transduction; Time Factors; Wortmannin | 2007 |
Changes in membrane potential during the progression of MCF-7 human mammary tumor cells through the cell cycle.
Topics: Breast Neoplasms; Cell Cycle; Estrogen Antagonists; Growth Inhibitors; Humans; Membrane Potentials; Potassium Channel Blockers; Quinidine; Tamoxifen; Tumor Cells, Cultured | 1995 |
Multidrug-resistance modulation in metastatic breast cancer patients.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Drug Resistance, Multiple; Epirubicin; Humans; Quinidine; Randomized Controlled Trials as Topic | 1995 |
Inhibition of ATP-sensitive potassium channels causes reversible cell-cycle arrest of human breast cancer cells in tissue culture.
Topics: 4-Aminopyridine; Breast Neoplasms; Cell Cycle; Cell Division; Glyburide; Humans; Potassium Channel Blockers; Potassium Channels; Pyrrolidines; Quinidine; Tetraethylammonium; Tetraethylammonium Compounds; Tumor Cells, Cultured | 1995 |
Evidence for an early G1 ionic event necessary for cell cycle progression and survival in the MCF-7 human breast carcinoma cell line.
Topics: Anti-Arrhythmia Agents; Antineoplastic Agents; Breast Neoplasms; Cell Death; Cell Survival; Dose-Response Relationship, Drug; G1 Phase; Humans; Ionophores; Ki-67 Antigen; Lovastatin; Membrane Potentials; Potassium Channels; Quinidine; Resting Phase, Cell Cycle; S Phase; Time Factors; Tumor Cells, Cultured; Valinomycin | 1998 |
An ATP-sensitive K(+) current that regulates progression through early G1 phase of the cell cycle in MCF-7 human breast cancer cells.
Topics: Adenosine Triphosphate; Breast Neoplasms; Calcium; Female; G1 Phase; Gene Expression; Genes, ras; Glyburide; Humans; Intracellular Fluid; Ion Transport; Membrane Potentials; Potassium; Potassium Channel Blockers; Pyrrolidines; Quinidine; Tetraethylammonium; Tumor Cells, Cultured | 1999 |
Rapid induction of histone hyperacetylation and cellular differentiation in human breast tumor cell lines following degradation of histone deacetylase-1.
Topics: Acetylation; Acetylcysteine; Animals; Anti-Bacterial Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Cell Division; Chickens; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytoskeleton; Down-Regulation; Enzyme Inhibitors; Female; G1 Phase; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Immunoblotting; Keratins; Leupeptins; Multienzyme Complexes; Peptides; Phosphorylation; Proteasome Endopeptidase Complex; Quinidine; Retinoblastoma Protein; Time Factors; Tumor Cells, Cultured | 2000 |
Study of tea polyphenol as a reversal agent for carcinoma cell lines' multidrug resistance (study of TP as a MDR reversal agent).
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Drug Interactions; Drug Resistance, Multiple; Flavonoids; Organophosphorus Compounds; Organotechnetium Compounds; Phenols; Plant Extracts; Polymers; Polyphenols; Quinidine; Tea; Tumor Cells, Cultured | 2001 |
Effect of P-glycoprotein expression on the accumulation and cytotoxicity of topotecan (SK&F 104864), a new camptothecin analogue.
Topics: Acute Disease; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Camptothecin; CHO Cells; Cricetinae; DNA Topoisomerases, Type I; DNA, Neoplasm; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Flow Cytometry; Leukemia; Membrane Glycoproteins; Quinidine; Topotecan; Tumor Cells, Cultured | 1992 |
Adequate tumour quinidine levels for multidrug resistance modulation can be achieved in vivo.
Topics: Animals; Breast Neoplasms; Cell Line; Cell Survival; Drug Resistance; Female; Humans; Mice; Mice, Nude; Quinidine; Tumor Cells, Cultured | 1992 |
A 23-pS Ca2(+)-activated K+ channel in MCF-7 human breast carcinoma cells: an apparent correlation of channel incidence with the rate of cell proliferation.
Topics: Apamin; Breast Neoplasms; Calcium; Cell Division; Electric Conductivity; Epithelium; Humans; Potassium; Potassium Channels; Quinidine; Rubidium; Tamoxifen; Tetradecanoylphorbol Acetate; Tetraethylammonium Compounds; Tumor Cells, Cultured | 1991 |
A pilot study of quinidine and epirubicin in the treatment of advanced breast cancer.
Topics: Adult; Aged; Breast Neoplasms; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epirubicin; Female; Humans; Leukocyte Count; Middle Aged; Pilot Projects; Platelet Count; Quinidine | 1990 |
Cross-resistance to the lipid-soluble antifolate trimetrexate in human carcinoma cells with the multidrug-resistant phenotype.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cell Line; Drug Resistance; Female; Genes; Humans; Methotrexate; Ovarian Neoplasms; Phenotype; Quinazolines; Quinidine; RNA, Messenger; Trimetrexate; Tumor Cells, Cultured; Verapamil | 1989 |