quinidine has been researched along with ALS - Amyotrophic Lateral Sclerosis in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 5 (41.67) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Locatelli, E; Plowman, EK; Tabor Gray, L; Vasilopoulos, T; Wymer, J | 1 |
| Burés, E; Ferrer, S; Luis Díaz, J; Sancho, J; Servera, E; Signes-Costa, J; Torrecilla, T | 1 |
| Allison, KM; Berry, JD; Cordella, C; Green, JR; Macklin, EA; Pattee, GL; Pioro, EP; Richburg, BD; Smith, RA | 1 |
| Fralick, M; Kesselheim, AS; Sacks, CA | 1 |
| Cudkowicz, M; Goslin, K; Macklin, EA; Meekins, G; Myers, K; Pattee, G; Pioro, E; Schoenfeld, D; Sirdofsky, M; Smith, R; Wymer, J; Yu, H | 1 |
| Brooks, BR; Cummings, J; Hepner, A; Kaye, R; Pioro, EP; Schiffer, R; Thisted, RA; Wynn, D | 1 |
| Garnock-Jones, KP | 1 |
| Appel, SH; Berg, JE; Bradley, WG; Brooks, BR; Olney, RK; Pope, LE; Smith, RA; Thisted, RA | 1 |
| Meininger, V | 1 |
| Brooks, BR; Smith, RA | 1 |
| Hingorani, VN; Kittrelle, JP | 1 |
| Britto, MR; Smith, RA; Valderhaug, KL; Wedlund, PJ; Zhang, Y | 1 |
1 review(s) available for quinidine and ALS - Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Dextromethorphan/quinidine: in pseudobulbar affect.
Topics: Amyotrophic Lateral Sclerosis; Crying; Dextromethorphan; Drug Combinations; Emotions; Female; Humans; Laughter; Male; Mood Disorders; Multiple Sclerosis; Quinidine | 2011 |
3 trial(s) available for quinidine and ALS - Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Enhanced Bulbar Function in Amyotrophic Lateral Sclerosis: The Nuedexta Treatment Trial.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Cross-Over Studies; Dextromethorphan; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Quinidine | 2017 |
Dextromethorphan plus ultra low-dose quinidine reduces pseudobulbar affect.
Topics: Adolescent; Adult; Affective Symptoms; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Dextromethorphan; Dose-Response Relationship, Drug; Drug Combinations; Electrocardiography; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Oxygen; Quinidine | 2010 |
Treatment of pseudobulbar affect in ALS with dextromethorphan/quinidine: a randomized trial.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Dextromethorphan; Double-Blind Method; Drug Combinations; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Male; Metabolic Clearance Rate; Middle Aged; Pseudobulbar Palsy; Quinidine; Receptors, N-Methyl-D-Aspartate; Treatment Outcome | 2004 |
8 other study(ies) available for quinidine and ALS - Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Dextromethorphan/quinidine for the treatment of bulbar impairment in amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Deglutition; Dextromethorphan; Humans; Quinidine; Speech | 2023 |
Effect of one-year dextromethorphan/quinidine treatment on management of respiratory impairment in amyotrophic lateral sclerosis.
Topics: Aged; Amyotrophic Lateral Sclerosis; Dextromethorphan; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Prospective Studies; Quinidine; Respiratory Insufficiency; Time Factors; Treatment Outcome | 2021 |
Additional evidence for a therapeutic effect of dextromethorphan/quinidine on bulbar motor function in patients with amyotrophic lateral sclerosis: A quantitative speech analysis.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Dextromethorphan; Drug Combinations; Female; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Quinidine; Speech | 2018 |
Assessment of Use of Combined Dextromethorphan and Quinidine in Patients With Dementia or Parkinson Disease After US Food and Drug Administration Approval for Pseudobulbar Affect.
Topics: Aged; Amyotrophic Lateral Sclerosis; Dementia; Dextromethorphan; Drug Combinations; Excitatory Amino Acid Antagonists; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Parkinson Disease; Pseudobulbar Palsy; Quinidine; United States; United States Food and Drug Administration | 2019 |
Treatment of emotional lability in ALS.
Topics: Affective Symptoms; Amyotrophic Lateral Sclerosis; Animals; Dextromethorphan; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Humans; Quinidine; Randomized Controlled Trials as Topic | 2005 |
Treatment of pseudobulbar affect in ALS.
Topics: Amyotrophic Lateral Sclerosis; Animals; Brain Chemistry; Dextromethorphan; Disease Models, Animal; Drug Combinations; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Humans; Pseudobulbar Palsy; Quinidine; Serotonin | 2005 |
Treatment of pseudobulbar affect in ALS: October 26 highlight and commentary.
Topics: Amyotrophic Lateral Sclerosis; Antitussive Agents; Clinical Trials as Topic; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Drug Combinations; Drug Resistance; Drug Synergism; Enzyme Inhibitors; Genetic Testing; Genotype; Humans; Pseudobulbar Palsy; Quinidine | 2005 |
Dextromethorphan: enhancing its systemic availability by way of low-dose quinidine-mediated inhibition of cytochrome P4502D6.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Biological Availability; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme Inhibitors; Dextromethorphan; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Middle Aged; Mixed Function Oxygenases; Quinidine | 1992 |