quinazolines has been researched along with Sarcoma in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.00) | 18.7374 |
| 1990's | 4 (20.00) | 18.2507 |
| 2000's | 3 (15.00) | 29.6817 |
| 2010's | 12 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hejduk, K; Pochop, L | 1 |
| Antoine, M; Bonnette, P; Cadranel, J; Cazes, A; Duruisseaux, M; Girard, N; Mazieres, J; Monnet, I; Ung, M; Vieira, T; Wislez, M | 1 |
| Barquin, E; Collins, B; Gardner, K; Judson, I; Jürgensmeier, JM; Leahy, M; Marotti, M; Scurr, M; Young, H | 1 |
| Anderes, K; Camacho, LH; Culotta, KS; Davis, DW; Ekmekcioglu, S; Falchook, GS; Fu, S; Garrido-Laguna, I; George, GC; Hong, DS; Kurzrock, R; Liu, W; Moulder, SL; Naing, A; Percy Ivy, S; Piha-Paul, S; Tsimberidou, AM; Wen, Y; Wheler, JJ | 1 |
| Beuschel, SL; Hillegass, JM; MacPherson, MB; Macura, SL; Miller, JM; Mossman, BT; Perkins, TN; Sayan, M; Shukla, A; Thompson, JK | 1 |
| Aichler, M; Borgmann, DM; Feuchtinger, A; Hauck, SM; Huber, K; Keller, U; Li, Z; Schwaiger, M; Walch, A; Zitzelsberger, H | 1 |
| Crowe, PJ; Garrett, K; Goldstein, D; Wang, X; Yang, JL; Yang, M; Zeps, N | 1 |
| Bolshakov, S; Dicker, A; Korchin, B; Lahat, G; Lazar, A; Lev, D; Merritt, W; Nguyen, T; Pollock, RE; Ren, W; Sood, A; Wei, C | 1 |
| Golabi, N; Jean-Claude, BJ; Larroque-Lombard, AL; Todorova, M; Williams, C | 1 |
| Billups, CA; Gorlick, R; Houghton, PJ; Keir, ST; Kolb, EA; Maris, JM; Morton, CL; Smith, MA; Wu, J | 1 |
| Belousov, R; Colombo, C; Ghadimi, MP; Hornick, JL; Lazar, AJ; Lev, D; Liu, J; Lopez, G; Peng, T; Reynoso, D; Xie, X; Young, ED; Zhu, QS | 1 |
| Caparelli, F; Hoff, PM; Sahade, M | 1 |
| Baldi, A; Citro, G; Fanciulli, M; Spugnini, EP | 1 |
| Cree, IA; Di Nicolantonio, F; Glaysher, S; Johnson, P; Knight, LA; Mercer, S; Sharma, S; Whitehouse, P | 1 |
| Dicker, A; Heymach, J; Korchin, B; Lazar, A; Lev, D; Pollock, RE; Ren, W; Wei, C; Zhu, QS | 1 |
| Betit-Yen, K; Gitterman, CO; Lee, G; Luell, S; Prendergast, JS; Skipski, VP; Stock, CC | 1 |
| Banerjee, D; Bertino, JR; Capiaux, GM; Ercikan-Abali, EA; Liu-Chen, X; Tong, Y; Zhao, SC | 1 |
| Bertino, JR; Li, WW; Tong, WP | 1 |
| Blay, JY; Hermans, C; Judson, I; Rodenhuis, S; Smith, M; van Glabbeke, M; Verweij, J | 1 |
| Antman, KH; Gonin, R; Licht, JD | 1 |
2 review(s) available for quinazolines and Sarcoma
| Article | Year |
|---|---|
Cediranib: a VEGF receptor tyrosine kinase inhibitor.
Topics: Animals; Antineoplastic Agents; Carcinoma, Renal Cell; Central Nervous System Neoplasms; Colorectal Neoplasms; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Female; Glioblastoma; Humans; Kidney Neoplasms; Lung Neoplasms; Male; Ovarian Neoplasms; Prostatic Neoplasms; Quinazolines; Receptor Protein-Tyrosine Kinases; Sarcoma | 2012 |
Preclinical models in electrochemotherapy: the role of veterinary patients.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Cat Diseases; Cats; Cisplatin; Dog Diseases; Dogs; Drug Evaluation, Preclinical; Electrochemotherapy; Epirubicin; Head and Neck Neoplasms; Melanoma; Mitoxantrone; Neoplasms; Quinazolines; Sarcoma; Thiophenes | 2012 |
3 trial(s) available for quinazolines and Sarcoma
| Article | Year |
|---|---|
Phase II study of cediranib in patients with advanced gastrointestinal stromal tumors or soft-tissue sarcoma.
Topics: Adult; Aged; Antineoplastic Agents; Biomarkers; Female; Fluorodeoxyglucose F18; Gastrointestinal Stromal Tumors; Humans; Male; Middle Aged; Neoplasm Staging; Positron-Emission Tomography; Protein Kinase Inhibitors; Quinazolines; Sarcoma; Tomography, X-Ray Computed; Treatment Outcome | 2014 |
Dual inhibition of the vascular endothelial growth factor pathway: a phase 1 trial evaluating bevacizumab and AZD2171 (cediranib) in patients with advanced solid tumors.
Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Cerebral Hemorrhage; Drug Administration Schedule; Female; Humans; Hypertension; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasms; Neoplastic Cells, Circulating; Quinazolines; Sarcoma; Signal Transduction; Treatment Outcome; Vascular Endothelial Growth Factor A | 2014 |
Phase II study of raltitrexed ('Tomudex') for patients with advanced soft tissue sarcomas refractory to doxorubicin-containing regimens.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Female; Humans; Male; Middle Aged; Neoplasm Metastasis; Neutropenia; Quinazolines; Sarcoma; Soft Tissue Neoplasms; Thiophenes; Thrombocytopenia; Treatment Outcome | 1999 |
15 other study(ies) available for quinazolines and Sarcoma
| Article | Year |
|---|---|
[Report from a small registry-permetrexed, tarceva and yondelis].
Topics: Antineoplastic Agents; ErbB Receptors; Erlotinib Hydrochloride; Glutamates; Guanine; Humans; Mesothelioma; Pancreatic Neoplasms; Pemetrexed; Protein Kinase Inhibitors; Quinazolines; Registries; Sarcoma | 2013 |
Efficacy of first-line chemotherapy in patients with advanced lung sarcomatoid carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinosarcoma; Deoxycytidine; Docetaxel; Erlotinib Hydrochloride; Female; Follow-Up Studies; Gemcitabine; Giant Cell Tumors; Glutamates; Guanine; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Paclitaxel; Pemetrexed; Prognosis; Quinazolines; Retrospective Studies; Sarcoma; Survival Rate; Taxoids; Vinblastine; Vinorelbine | 2013 |
Extracellular signal-regulated kinase 5 and cyclic AMP response element binding protein are novel pathways inhibited by vandetanib (ZD6474) and doxorubicin in mesotheliomas.
Topics: Antibiotics, Antineoplastic; Cell Line, Tumor; Cell Survival; Cyclic AMP Response Element-Binding Protein; Doxorubicin; Drug Synergism; Humans; MAP Kinase Signaling System; Mesothelioma; Mitogen-Activated Protein Kinase 7; Neoplasms, Connective Tissue; Phosphorylation; Piperidines; Quinazolines; RNA, Small Interfering; Sarcoma | 2014 |
Novel approach of MALDI drug imaging, immunohistochemistry, and digital image analysis for drug distribution studies in tissues.
Topics: Afatinib; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Erlotinib Hydrochloride; Female; Immunohistochemistry; Mice; Mice, SCID; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Quinazolines; Sarcoma; Sorafenib; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tissue Distribution | 2014 |
Overcoming resistance of targeted EGFR monotherapy by inhibition of STAT3 escape pathway in soft tissue sarcoma.
Topics: Aminosalicylic Acids; Animals; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Blotting, Western; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; ErbB Receptors; Gefitinib; Humans; Mice, Inbred BALB C; Mice, Nude; Mutation; Protein Kinase Inhibitors; Quinazolines; Sarcoma; Signal Transduction; STAT3 Transcription Factor; Treatment Outcome; Xenograft Model Antitumor Assays | 2016 |
Combined vascular endothelial growth factor receptor/epidermal growth factor receptor blockade with chemotherapy for treatment of local, uterine, and metastatic soft tissue sarcoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; ErbB Receptors; Female; Humans; Lung Neoplasms; Mice; Mice, Nude; Muscle Neoplasms; Piperidines; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Sarcoma; Tumor Cells, Cultured; Uterine Neoplasms; Xenograft Model Antitumor Assays | 2008 |
Synthesis and uptake of fluorescence-labeled Combi-molecules by P-glycoprotein-proficient and -deficient uterine sarcoma cells MES-SA and MES-SA/DX5.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Proliferation; Comet Assay; Dansyl Compounds; DNA; DNA Damage; ErbB Receptors; Female; Flow Cytometry; Half-Life; Humans; Magnetic Resonance Spectroscopy; Microscopy, Fluorescence; Quinazolines; Sarcoma; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Uterine Neoplasms | 2010 |
Combination testing of cediranib (AZD2171) against childhood cancer models by the pediatric preclinical testing program.
Topics: Adolescent; Animals; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Female; Glioblastoma; Humans; Infant; Mice; Mice, Inbred BALB C; Mice, Nude; Mice, SCID; Neoplasm Transplantation; Neuroblastoma; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Sarcoma; Sirolimus; Transplantation, Heterologous; Xenograft Model Antitumor Assays | 2012 |
Combining EGFR and mTOR blockade for the treatment of epithelioid sarcoma.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Models, Animal; Drug Synergism; ErbB Receptors; Erlotinib Hydrochloride; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasm Invasiveness; Quinazolines; Sarcoma; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays | 2011 |
The in vitro effect of gefitinib ('Iressa') alone and in combination with cytotoxic chemotherapy on human solid tumours.
Topics: Adenocarcinoma; Adenosine Triphosphate; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Busulfan; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cisplatin; Colorectal Neoplasms; Deoxycytidine; Drug Screening Assays, Antitumor; Female; Gefitinib; Gemcitabine; Humans; Melanoma; Neoplasms; Neoplasms, Unknown Primary; Organoplatinum Compounds; Ovarian Neoplasms; Oxaliplatin; Quinazolines; Sarcoma; Skin Neoplasms; Stomach Neoplasms; Uveal Neoplasms | 2004 |
Epidermal growth factor receptor blockade in combination with conventional chemotherapy inhibits soft tissue sarcoma cell growth in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Drug Synergism; ErbB Receptors; Gefitinib; Humans; Mice; Mice, Nude; Quinazolines; Sarcoma | 2008 |
Possible relationship between glycosphingolipids and the formation of metastasis in certain human experimental tumors.
Topics: Animals; Carcinoma, Squamous Cell; Chick Embryo; Gangliosides; Glycosphingolipids; Humans; Neoplasm Metastasis; Neoplasms, Experimental; Quinazolines; Sarcoma; Thiazoles | 1980 |
Isolation and characterization of thymitaq (AG337) and 5-fluoro-2-deoxyuridylate-resistant mutants of human thymidylate synthase from ethyl methanesulfonate-exposed human sarcoma HT1080 cells.
Topics: Cloning, Molecular; Drug Resistance; Enzyme Inhibitors; Escherichia coli; Ethyl Methanesulfonate; Fluorodeoxyuridylate; Folic Acid; Folic Acid Antagonists; Gene Expression Regulation, Enzymologic; Humans; Kinetics; Mutagenesis; Mutagenesis, Site-Directed; Polymorphism, Single-Stranded Conformational; Quinazolines; Recombinant Proteins; Sarcoma; Thymidylate Synthase; Tumor Cells, Cultured | 1998 |
Antitumor activity of antifolate inhibitors of thymidylate and purine synthesis in human soft tissue sarcoma cell lines with intrinsic resistance to methotrexate.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Biological Transport; Biotransformation; Cell Division; Cell Survival; Drug Resistance, Neoplasm; Folic Acid Antagonists; Humans; Indoles; Isoindoles; Kinetics; Methotrexate; Purines; Quinazolines; Sarcoma; Tetrahydrofolates; Thiophenes; Thymidine Monophosphate; Tumor Cells, Cultured | 1995 |
Phase II trial of trimetrexate in patients with advanced soft-tissue sarcoma.
Topics: Antineoplastic Agents; Drug Evaluation; Folic Acid Antagonists; Humans; Infusions, Intravenous; Quinazolines; Remission Induction; Sarcoma; Soft Tissue Neoplasms; Time Factors; Trimetrexate | 1991 |