quinazolines has been researched along with Rectal Neoplasms in 41 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.88) | 18.7374 |
| 1990's | 2 (4.88) | 18.2507 |
| 2000's | 21 (51.22) | 29.6817 |
| 2010's | 13 (31.71) | 24.3611 |
| 2020's | 3 (7.32) | 2.80 |
| Authors | Studies |
|---|---|
| Artru, P; Auclin, E; Basile, D; Coutzac, C; Dior, M; Dubreuil, O; Faroux, R; Gallois, C; Hafliger, E; Hautefeuille, V; Locher, C; Palmieri, LJ; Pellat, A; Pernot, S; Perret, A; Randrian, V; Taieb, J; Turpin, A | 1 |
| Cho, CS; Choi, EK; Ganguly, A; Hardiman, KM; Irwin, RK; Leopold, J; McLeod, MC; Pepple, A; Smithson, M; Willey, CD; Williams, G | 1 |
| Cao, Y; Chen, M; Li, J; Lu, M; Peng, Z; Qi, C; Shen, L; Wang, X; Wang, Z; Zhang, J; Zhang, Q | 1 |
| Chen, J; Lin, H; Peng, Y; Wang, J | 1 |
| Allen, J; Backen, AC; Connell, J; Dive, C; Jackson, A; Jayson, GC; Li, K; Manoharan, P; Marti, FEM; Misra, V; Mistry, H; O'Connor, J; Ortega, F; Renehan, AG; Saunders, MP; Simpson, KL; Stratford, I; Underhill, S; Williams, KJ | 1 |
| Chang, GJ; Clemons, MV; Crane, CH; Das, P; Delclos, ME; Eng, C; Garrett, CR; Kopetz, SE; Krishnan, S; Maru, DM; Munsell, MF; Rodriguez-Bigas, MA; Shureiqi, I; Skibber, JM; You, YN | 1 |
| Allen, JN; Berger, DL; Blaszkowsky, LS; Borger, DR; Clark, JW; Cusack, JC; Hong, TS; Kwak, EL; Mamon, HJ; Ryan, DP; Shellito, PC; Szymonifka, J; Vasudev, E; Zhu, AX | 1 |
| Chu, QS; Hennig, R; Kim, CA; Price-Hiller, J; Sawyer, MB; Spratlin, JL; Tankel, K | 1 |
| Cheung, WY; Doll, C; Goodwin, R; Heng, DY; Jiang, DM; Kumar, A; MacLean, A; Mercer, J; Monzon, J; Powell, E; Price-Hiller, J; Raissouni, S; Tang, PA; Vickers, MM | 1 |
| Aloj, L; Avallone, A; Bianco, F; Botti, G; Budillon, A; Caracò, C; Comella, P; Delrio, P; Granata, V; Iaffaioli, VR; Leone, A; Marone, P; Muto, P; Pecori, B; Petrillo, A; Romano, C; Romano, G; Tatangelo, F | 1 |
| Arcelli, A; Ardizzoni, A; Caravatta, L; Cellini, F; Cilla, S; Cuicchi, D; Deodato, F; DI Fabio, F; Farioli, A; Frezza, G; Fuccio, L; Gambacorta, MA; Giaccherini, L; Guido, A; Macchia, G; Morganti, AG; Picardi, V; Poggioli, G; Valentini, V | 1 |
| Glynne-Jones, R; Harrison, M; Mawdsley, S | 1 |
| Agostini, M; Biason, P; Canzonieri, V; Cecchin, E; De Mattia, E; De Paoli, A; Friso, ML; Nitti, D; Pucciarelli, S; Sigon, R; Toffoli, G; Visentin, M | 1 |
| Aloi, L; Avallone, A; Budillon, A; Comella, P; Delrio, P; Iaffaioli, VR; Iodice, G; Lastoria, S; Marone, P; Pecori, B; Petrillo, A; Sandomenico, C; Scala, D; Scott, N; Tatangelo, F | 1 |
| Berardi, S; Caravatta, L; Cellini, N; Deodato, F; Di Filippo, L; Fabrizio, G; Ingrosso, M; Macchia, G; Massaccesi, M; Morganti, AG; Pacelli, F; Padula, GD; Picardi, V; Ridolfini, MP; Tambaro, R; Valentini, V | 1 |
| Bonomo, P; Caravatta, L; Cecere, G; Cellini, N; Deodato, F; Di Lullo, L; Macchia, G; Massaccesi, M; Mignogna, S; Morganti, AG; Pacelli, F; Padula, GD; Picardi, V; Piscopo, A; Rotondi, F; Sallustio, G; Sofo, L; Valentini, V | 1 |
| Botwood, N; James, RD; Price, P; Vernon, CC | 1 |
| Beatrix, O; Dumortier, J; Lapalus, MG; Lombard-Bohas, C; Scoazec, JY; Villarejo, J; Vochelle, V | 1 |
| Alfieri, S; Cellini, N; De Paoli, A; Di Miceli, D; Doglietto, GB; Gambacorta, MA; Mantini, G; Miccichè, F; Morganti, AG; Ratto, C; Rossi, C; Rotondi, F; Valentini, V; Vargas, JG | 1 |
| Barbaro, B; Cellini, N; Coco, C; Gambacorta, MA; Garcia-Vargas, JE; Magistrelli, P; Mantini, G; Miccichè, F; Morganti, AG; Picciocchi, A; Smaniotto, D; Valentini, V | 1 |
| André, T; de Gramont, A; Gamelin, E; Garcia, ML; Kalla, S; Lenaers, G; Louvet, C; Méry-Mignard, D; Saavedra, A | 1 |
| Bolzicco, G; Coco, C; Dalla Palma, M; De Paoli, A; Di Russo, A; Doglietto, GB; Gambacorta, MA; Mohiuddin, M; Morganti, AG; Rossi, C; Valentini, V; Valvo, F | 1 |
| Bendell, JC; Blobe, GC; Clary, BM; Czito, BG; Fernando, NH; Honeycutt, W; Hurwitz, HI; Ludwig, KA; Mantyh, CR; Morse, MA; Pappas, TN; Tyler, DS; Willett, CG; Yu, D | 1 |
| Bragg, J; Pomeranz, MK | 1 |
| Czaykowski, PM | 1 |
| Bendell, JC; Clark, JW; Czito, BG; Duda, DG; Jain, RK; Willett, CG | 1 |
| Barbera, F; Bellavita, R; Coco, C; Cosimelli, M; Gambacorta, MA; Genovesi, D; La Torre, G; Lupattelli, M; Maranzano, E; Maurizi-Enrici, R; Minsky, BD; Morganti, AG; Portaluri, M; Trodella, L; Valentini, V | 1 |
| Erickson, LA; Hobday, T; Jin, L; Leontovich, AA; Lloyd, RV; Ruebel, KH; Stilling, GA; Tanizaki, Y; Zhang, H; Zhang, S | 1 |
| Barutca, S; Bolaman, Z; Kadikoylu, G; Meydan, N; Yavasoglu, I | 1 |
| Barba, MC; Barbaro, B; Boz, G; De Paoli, A; Doglietto, GB; Frattegiani, A; Gambacorta, MA; Innocente, R; Lupattelli, M; Mantini, G; Ratto, C; Rossi, C; Valentini, V; Vecchio, FM | 1 |
| Bours, V; Fillet, G; Jerusalem, G | 1 |
| James, R; Price, P; Valentini, V | 1 |
| Ebata, T; Kikkawa, N; Mitachi, Y; Nishiguchi, Y; Nishisho, I; Osanai, H; Sawai, K; Tsutsui, M; Ujiie, S; Wakasugi, H; Wakui, A; Yasutake, K | 1 |
| Avallone, A; Casaretti, R; Catalano, G; Comella, G; Comella, P; De Lucia, L; De Vita, F; Orditura, M; Palmeri, S; Rivellini, F | 1 |
| Botwood, N; James, R; Price, P; Vernon, C | 1 |
| Artigue, F; Buffet, C; Cassan, P; Flamenbaum, M; Garcia, V; Kemeny, JL | 1 |
| Avallone, A; Budillon, A; Caponigro, F; Comella, G; Comella, P | 1 |
| Cellini, N; De Santis, M; Doglietto, GB; Morganti, AG; Ratto, C; Smaniotto, D; Sofo, L; Turriziani, A; Valentini, V | 1 |
| Reutova, EV | 1 |
| Cantwell, BM; Harris, AL | 1 |
| Cantwell, BM; Harding, MJ; Harris, AL; Kaye, SB; Milstead, RA | 1 |
5 review(s) available for quinazolines and Rectal Neoplasms
| Article | Year |
|---|---|
Comparison of Regorafenib, Fruquintinib, and TAS-102 in Previously Treated Patients with Metastatic Colorectal Cancer: A Systematic Review and Network Meta-Analysis of Five Clinical Trials.
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzofurans; Colonic Neoplasms; Colorectal Neoplasms; Disease-Free Survival; Drug Combinations; Humans; Network Meta-Analysis; Phenylurea Compounds; Pyridines; Pyrrolidines; Quinazolines; Rectal Neoplasms; Thymine; Trifluridine; Uracil | 2019 |
Cetuximab and chemoradiation for rectal cancer--is the water getting muddy?
Topics: Adenocarcinoma; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Cetuximab; Chemotherapy, Adjuvant; Deoxycytidine; ErbB Receptors; Fluorouracil; Gefitinib; Humans; Irinotecan; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Panitumumab; Quinazolines; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Rectal Neoplasms; Treatment Failure | 2010 |
Targeted therapy in rectal cancer.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Camptothecin; Cetuximab; Drug Delivery Systems; Epidermal Growth Factor; Erlotinib Hydrochloride; Gefitinib; Humans; Irinotecan; Neoadjuvant Therapy; Quinazolines; Rectal Neoplasms; Vascular Endothelial Growth Factor A | 2007 |
[Drug clinics. How I treat. II. Therapeutic approaches to metastatic colorectal cancer].
Topics: Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Colonic Neoplasms; Enzyme Inhibitors; Fluorouracil; Hospitalization; Humans; Irinotecan; Leucovorin; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Palliative Care; Quality of Life; Quinazolines; Rectal Neoplasms; Thiophenes; Thymidylate Synthase; Topoisomerase I Inhibitors | 1998 |
Raltitrexed/5-fluorouracil-based combination chemotherapy regimens in anticancer therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colorectal Neoplasms; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Neoplasm Metastasis; Neoplasms; Organoplatinum Compounds; Oxaliplatin; Quinazolines; Rectal Neoplasms; Thiophenes | 2001 |
20 trial(s) available for quinazolines and Rectal Neoplasms
| Article | Year |
|---|---|
Novel phase I trial design to evaluate the addition of cediranib or selumetinib to preoperative chemoradiotherapy for locally advanced rectal cancer: the DREAMtherapy trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Biomarkers, Tumor; Chemoradiotherapy; Cohort Studies; Female; Follow-Up Studies; Humans; Male; Maximum Tolerated Dose; Middle Aged; Prognosis; Quinazolines; Rectal Neoplasms; Tissue Distribution | 2019 |
Preoperative radiation therapy with concurrent capecitabine, bevacizumab, and erlotinib for rectal cancer: a phase 1 trial.
Topics: Adenocarcinoma; Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Chemoradiotherapy; Deoxycytidine; Disease-Free Survival; Drug Administration Schedule; Early Termination of Clinical Trials; Erlotinib Hydrochloride; Female; Fluorouracil; Humans; Male; Maximum Tolerated Dose; Middle Aged; Preoperative Care; Quinazolines; Radiotherapy Dosage; Rectal Neoplasms | 2014 |
Phase I/II study of neoadjuvant bevacizumab, erlotinib and 5-fluorouracil with concurrent external beam radiation therapy in locally advanced rectal cancer.
Topics: Adenocarcinoma; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Chemoradiotherapy; Chemotherapy, Adjuvant; Disease-Free Survival; Erlotinib Hydrochloride; Female; Fluorouracil; Humans; Male; Neoadjuvant Therapy; Quinazolines; Rectal Neoplasms; Treatment Outcome | 2014 |
Critical role of bevacizumab scheduling in combination with pre-surgical chemo-radiotherapy in MRI-defined high-risk locally advanced rectal cancer: Results of the BRANCH trial.
Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Chemoradiotherapy, Adjuvant; Disease Progression; Disease-Free Survival; Drug Administration Schedule; Early Termination of Clinical Trials; Female; Fluorouracil; Humans; Italy; Kaplan-Meier Estimate; Leucovorin; Magnetic Resonance Imaging; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Predictive Value of Tests; Quinazolines; Rectal Neoplasms; Risk Factors; Thiophenes; Time Factors; Treatment Outcome | 2015 |
Concurrent Chemoradiation with Concomitant Boost in Locally Advanced Rectal Cancer: A Phase II Study.
Topics: Adult; Aged; Chemoradiotherapy; Combined Modality Therapy; Disease-Free Survival; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Quinazolines; Radiotherapy Dosage; Rectal Neoplasms; Thiophenes | 2016 |
Neoadjuvant accelerated concomitant boost radiotherapy and multidrug chemotherapy in locally advanced rectal cancer: a dose-escalation study.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Female; Follow-Up Studies; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Peritoneal Neoplasms; Quinazolines; Rectal Neoplasms; Thiophenes; Treatment Outcome | 2012 |
Concomitant boost radiotherapy and multidrug chemotherapy in the neoadjuvant treatment of locally advanced rectal cancer: results of a phase II study.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Chemotherapy, Adjuvant; Female; Humans; Infusions, Intravenous; Magnetic Resonance Imaging; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Quinazolines; Radiotherapy; Radiotherapy, Adjuvant; Rectal Neoplasms; Thiophenes | 2011 |
Raltitrexed plus radiotherapy for the treatment of unresectable/recurrent rectal cancer: a phase I study.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Diarrhea; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Neutropenia; Quinazolines; Rectal Neoplasms; Thiophenes | 2003 |
Chemoradiation with raltitrexed (Tomudex) in preoperative treatment of stage II-III resectable rectal cancer: a phase II study.
Topics: Aged; Antimetabolites, Antineoplastic; Female; Fluorouracil; Folic Acid; Follow-Up Studies; Hematinics; Humans; Male; Middle Aged; Neoplasm Staging; Quinazolines; Radiotherapy, Conformal; Rectal Neoplasms; Thiophenes | 2004 |
Chemoradiation with raltitrexed and oxaliplatin in preoperative treatment of stage II-III resectable rectal cancer: Phase I and II studies.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Quinazolines; Radiotherapy Dosage; Rectal Neoplasms; Thiophenes | 2004 |
A phase I-II, dose-escalating trial of ZD9331 in combination with irinotecan (CPT11) in previously pretreated metastatic colorectal cancer patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Drug Administration Schedule; Female; Humans; Irinotecan; Male; Maximum Tolerated Dose; Middle Aged; Neutropenia; Quinazolines; Rectal Neoplasms | 2004 |
Preoperative hyperfractionated chemoradiation for locally recurrent rectal cancer in patients previously irradiated to the pelvis: A multicentric phase II study.
Topics: Adult; Aged; Analysis of Variance; Antineoplastic Agents; Combined Modality Therapy; Dose Fractionation, Radiation; Female; Fluorouracil; Humans; Italy; Male; Middle Aged; Neoplasm Recurrence, Local; Pain Management; Quinazolines; Radiotherapy; Rectal Neoplasms; Thiophenes; Treatment Failure | 2006 |
Increased toxicity with gefitinib, capecitabine, and radiation therapy in pancreatic and rectal cancer: phase I trial results.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; ErbB Receptors; Female; Fluorouracil; Gefitinib; Humans; Male; Middle Aged; Neoplasm Staging; Pancreatic Neoplasms; Quinazolines; Radiotherapy, Adjuvant; Rectal Neoplasms | 2006 |
Randomized, multicenter, phase IIb study of preoperative chemoradiotherapy in T3 mid-distal rectal cancer: raltitrexed + oxaliplatin + radiotherapy versus cisplatin + 5-fluorouracil + radiotherapy.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Prospective Studies; Quinazolines; Radiotherapy Dosage; Rectal Neoplasms; Thiophenes | 2008 |
Infusional 5-fluorouracil and ZD1839 (Gefitinib-Iressa) in combination with preoperative radiotherapy in patients with locally advanced rectal cancer: a phase I and II Trial (1839IL/0092).
Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Diarrhea; Drug Tolerance; Female; Fluorouracil; Gastrointestinal Diseases; Gefitinib; Humans; Infusions, Intravenous; Male; Neoplasm Staging; Quinazolines; Radiotherapy Dosage; Rectal Neoplasms; Safety | 2008 |
Raltitrexed (Tomudex) concomitant with radiotherapy as adjuvant treatment for patients with rectal cancer: preliminary results of phase I studies.
Topics: Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Quinazolines; Radiotherapy, Adjuvant; Rectal Neoplasms; Thiophenes; Treatment Outcome | 1999 |
[A late phase II study of raltitrexed (ZD 1694) in chemotherapy-naive patients with advanced colorectal cancer].
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Colonic Neoplasms; Drug Administration Schedule; Enzyme Inhibitors; Female; Humans; Leukopenia; Male; Middle Aged; Quinazolines; Rectal Neoplasms; Thiophenes; Thymidylate Synthase | 2000 |
Oxaliplatin and raltitrexed combined with leucovorin-modulated 5-fluorouracil i.v. bolus every two weeks: a dose finding study in advanced previously treated colorectal carcinoma. Southern Italy Cooperative Oncology Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Female; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Quinazolines; Rectal Neoplasms; Thiophenes; Treatment Outcome | 2000 |
Raltitrexed ('Tomudex') and radiotherapy can be combined as postoperative treatment for rectal cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Combined Modality Therapy; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Neutropenia; Pneumonia; Quinazolines; Radiotherapy, Adjuvant; Rectal Neoplasms; Thiophenes; Treatment Outcome | 2000 |
Preoperative chemoradiation with raltitrexed ('Tomudex') for T2/N+ and T3/N+ rectal cancers: a phase I study.
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Dose-Response Relationship, Drug; Female; Humans; Leukopenia; Male; Middle Aged; Quinazolines; Radiotherapy, Adjuvant; Rectal Neoplasms; Thiophenes | 2001 |
16 other study(ies) available for quinazolines and Rectal Neoplasms
| Article | Year |
|---|---|
First-line chemotherapy with raltitrexed in metastatic colorectal cancer: an Association des Gastro-entérologues Oncologues (AGEO) multicentre study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colonic Neoplasms; Colorectal Neoplasms; Humans; Quinazolines; Rectal Neoplasms; Retrospective Studies; Thiophenes | 2022 |
Inhibition of DNA-PK may improve response to neoadjuvant chemoradiotherapy in rectal cancer.
Topics: Animals; Chemoradiotherapy; DNA; Humans; Mice; Neoadjuvant Therapy; Pyridazines; Quinazolines; Rectal Neoplasms; Treatment Outcome | 2022 |
Efficacy and Safety Comparison of Regorafenib and Fruquintinib in Metastatic Colorectal Cancer-An Observational Cohort Study in the Real World.
Topics: Benzofurans; Colonic Neoplasms; Colorectal Neoplasms; Humans; Phenylurea Compounds; Prospective Studies; Pyridines; Quinazolines; Rectal Neoplasms; Retrospective Studies | 2022 |
Atypical reversible posterior leukoencephalopathy syndrome (RPLS) induced by cediranib in a patient with metastatic rectal cancer.
Topics: Aged; Angiogenesis Inhibitors; Antineoplastic Agents; Humans; Male; Posterior Leukoencephalopathy Syndrome; Protein Kinase Inhibitors; Quinazolines; Rectal Neoplasms | 2014 |
Clinical outcomes of elderly patients receiving neoadjuvant chemoradiation for locally advanced rectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Chemotherapy, Adjuvant; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prognosis; Quinazolines; Rectal Neoplasms; Retrospective Studies; Survival Rate; Thiophenes; Young Adult | 2015 |
Tumor response is predicted by patient genetic profile in rectal cancer patients treated with neo-adjuvant chemo-radiotherapy.
Topics: Adult; Aged; Female; Fluorouracil; Gene Expression Profiling; Genetic Association Studies; Genotype; Humans; Male; Middle Aged; Multidrug Resistance-Associated Protein 2; Neoadjuvant Therapy; Neoplasm Staging; Polymorphism, Single Nucleotide; Quinazolines; Rectal Neoplasms; Thiophenes; Treatment Outcome | 2011 |
Oxaliplatin plus dual inhibition of thymidilate synthase during preoperative pelvic radiotherapy for locally advanced rectal carcinoma: long-term outcome.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Diarrhea; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoplasm Proteins; Neoplasm Staging; Neutropenia; Organoplatinum Compounds; Oxaliplatin; Postoperative Complications; Preoperative Care; Prognosis; Quinazolines; Radiotherapy Dosage; Rectal Neoplasms; Remission Induction; Thiophenes; Thymidylate Synthase; Treatment Outcome; Vitamin B Complex | 2011 |
[Severe acute cytomegalovirus colitis after administration of irinotecan and raltitrexed chemotherapy].
Topics: Acute Disease; Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Camptothecin; Colitis; Cytomegalovirus Infections; Ganciclovir; Humans; Immunocompromised Host; Irinotecan; Male; Quinazolines; Rectal Neoplasms; Sigmoid Neoplasms; Thiophenes | 2003 |
Papulopustular drug eruption due to an epidermal growth factor receptor inhibitors, erlotinib and cetuximab.
Topics: Adenocarcinoma; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Cetuximab; Drug Eruptions; ErbB Receptors; Erlotinib Hydrochloride; Follow-Up Studies; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Protein Kinase Inhibitors; Quinazolines; Rectal Neoplasms; Rosacea | 2007 |
Therapy of colon carcinoma: an oncology perspective. Interview with Piotr M. Czaykowski by Paul C. Adams.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Carcinoembryonic Antigen; Carcinoma; Colonic Neoplasms; Combined Modality Therapy; Fluorouracil; Humans; Irinotecan; Quinazolines; Rectal Neoplasms; Thiophenes | 2007 |
Characterization of the functional and growth properties of cell lines established from ileal and rectal carcinoid tumors.
Topics: Adenoviridae; Antigens, Polyomavirus Transforming; Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoid Tumor; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Gefitinib; Gene Expression Profiling; Genetic Vectors; Humans; Ileal Neoplasms; Immunohistochemistry; Octreotide; Oligonucleotide Array Sequence Analysis; Quinazolines; Receptors, Calcitriol; Receptors, Somatostatin; Rectal Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Transforming Growth Factors | 2007 |
Chronic myeloid leukemia following the treatment of rectal adenocarcinoma.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Deoxycytidine; Fluorouracil; Fusion Proteins, bcr-abl; Humans; In Situ Hybridization, Fluorescence; Irinotecan; Leucovorin; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Liver Neoplasms; Male; Neoplasms, Second Primary; Organoplatinum Compounds; Oxaliplatin; Philadelphia Chromosome; Quinazolines; Rectal Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Thiophenes | 2008 |
[Non-alcoholic steatohepatitis with cirrhosis after raltitrexed administration].
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Disease Progression; Drug Monitoring; Fat Necrosis; Fatty Liver; Female; Humans; Liver Cirrhosis; Liver Function Tests; Middle Aged; Quinazolines; Rectal Neoplasms; Thiophenes; Thymidylate Synthase | 2001 |
[Irinotecan and tomudex in the treatment of patients with advanced cancer of the large intestine].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Colonic Neoplasms; Female; Humans; Irinotecan; Male; Middle Aged; Quinazolines; Rectal Neoplasms; Thiophenes; Time Factors | 2001 |
The efficacy of 5-fluorouracil in human colorectal cancer is not enhanced by thymidylate synthetase inhibition with CB3717 (N10-propargyl-5,8 dideazafolic acid).
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fluorouracil; Folic Acid; Humans; Middle Aged; Quinazolines; Rectal Neoplasms; Thymidylate Synthase | 1988 |
Phase II study of the thymidylate synthetase inhibitor CB3717 (N10-propargyl-5,8-dideazafolic acid) in colorectal cancer.
Topics: Adult; Aged; Antineoplastic Agents; Colonic Neoplasms; Drug Evaluation; Female; Folic Acid; Humans; Male; Middle Aged; Quinazolines; Rectal Neoplasms | 1988 |