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quinazolines and Pulmonary Disease, Chronic Obstructive

quinazolines has been researched along with Pulmonary Disease, Chronic Obstructive in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's7 (63.64)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Dabo, AJ; Ezegbunam, W; Foronjy, RF; Geraghty, P; Lora, A; Majka, SM; Moon, J; Railwah, C; Wyman, AE1
Evans, R; Raubo, P; Willis, P1
Dharmarajan, S; Dinavahi, SS; Nyayapathy, S; Perumal, Y; Viswanadha, S1
Amatngalim, GD; Hiemstra, PS; Scholte, BJ; Stolarczyk, M; Veltman, M; Yu, X1
Atkinson, JJ; Borchers, MT; Deshmukh, HS; Di, PY; Dietsch, M; Hardie, WD; Korfhagen, TR; Leikauf, GD; Liu, Y; McLachlan, A; Wesselkamper, SC1
Adcock, IM; Barnes, PJ; Elliott, WM; Failla, M; Hogg, JC; Ito, K; Ito, M; Kizawa, Y; Kusama, T; To, Y1
Brandenburg, SM; Heijink, IH; Postma, DS; van Oosterhout, AJ1
Black, JL; Burgess, JK; Ge, Q; Moir, LM; Niimi, K; Oliver, BG; Poniris, M; Shepherd, PR; Trian, T1
Barnes, PJ; Ito, K; Ito, M; Osoata, G; Rossios, C; To, Y1
Chung, KF; Huang, CD; Huang, TT; Kuo, HP; Lee, KY; Lin, HC; Lin, SM; Lo, YL; Wang, CH1
Brun, L; Colin, G; Copin, MC; Lafitte, JJ; Makris, D; Marquette, CH; Scherpereel, A1

Other Studies

11 other study(ies) available for quinazolines and Pulmonary Disease, Chronic Obstructive

ArticleYear
Targeting c-Src Reverses Accelerated GPX-1 mRNA Decay in Chronic Obstructive Pulmonary Disease Airway Epithelial Cells.
    American journal of respiratory cell and molecular biology, 2020, Volume: 62, Issue:5

    Topics: Animals; Benzodioxoles; Enzyme Activation; Epithelial Cells; Epithelium; Female; Gene Expression Regulation; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Lung; Male; Mice; Proto-Oncogene Proteins pp60(c-src); Pulmonary Disease, Chronic Obstructive; Quinazolines; RNA Stability; Smoking

2020
The discovery and evaluation of 3-amino-2(1H)-pyrazinones as a novel series of selective p38α MAP kinase inhibitors.
    Bioorganic & medicinal chemistry letters, 2020, 09-15, Volume: 30, Issue:18

    Topics: Administration, Inhalation; Alkanes; Amines; Animals; Anti-Inflammatory Agents; Benzamides; Dogs; Drug Evaluation, Preclinical; Humans; Inflammation; Mitogen-Activated Protein Kinase 14; Models, Molecular; Protein Kinase Inhibitors; Pulmonary Disease, Chronic Obstructive; Pyrazines; Quinazolines; Rats; Structure-Activity Relationship

2020
Combined inhibition of PDE4 and PI3Kδ modulates the inflammatory component involved in the progression of chronic obstructive pulmonary disease.
    Drug research, 2014, Volume: 64, Issue:4

    Topics: Adenine; Aminopyridines; Benzamides; Cell Line, Tumor; Class I Phosphatidylinositol 3-Kinases; Cyclopropanes; Disease Progression; Humans; Lipopolysaccharides; Macrophages; Matrix Metalloproteinase 9; Neutrophils; Nicotiana; Phosphodiesterase 4 Inhibitors; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pulmonary Alveoli; Pulmonary Disease, Chronic Obstructive; Quinazolines; Smoke; U937 Cells

2014
ADAM17 and EGFR regulate IL-6 receptor and amphiregulin mRNA expression and release in cigarette smoke-exposed primary bronchial epithelial cells from patients with chronic obstructive pulmonary disease (COPD).
    Physiological reports, 2016, Volume: 4, Issue:16

    Topics: ADAM17 Protein; Aged; Airway Remodeling; Amphiregulin; Bronchi; Epithelial Cells; ErbB Receptors; Female; Humans; Inhalation Exposure; Male; Middle Aged; Nicotiana; Pulmonary Disease, Chronic Obstructive; Quinazolines; Receptors, Interleukin-6; RNA, Messenger; Signal Transduction; Smoking; Tyrphostins

2016
Matrix metalloproteinase-14 mediates a phenotypic shift in the airways to increase mucin production.
    American journal of respiratory and critical care medicine, 2009, Nov-01, Volume: 180, Issue:9

    Topics: Acrolein; Animals; Enzyme Activation; Epithelial Cells; Erlotinib Hydrochloride; Gene Expression Regulation, Enzymologic; Humans; Lung; Matrix Metalloproteinase 14; Mice; Mucins; Protein Kinase Inhibitors; Pulmonary Disease, Chronic Obstructive; Quinazolines; Respiratory Mucosa

2009
Targeting phosphoinositide-3-kinase-delta with theophylline reverses corticosteroid insensitivity in chronic obstructive pulmonary disease.
    American journal of respiratory and critical care medicine, 2010, Oct-01, Volume: 182, Issue:7

    Topics: Adenine; Animals; Anti-Inflammatory Agents; Case-Control Studies; Dexamethasone; Drug Resistance; Histone Deacetylase 2; Humans; Leukocytes, Mononuclear; Mice; Oxidative Stress; Phosphodiesterase Inhibitors; Phosphoinositide-3 Kinase Inhibitors; Pulmonary Disease, Chronic Obstructive; Quinazolines; RNA Interference; Smoking; Theophylline; Tobacco Smoke Pollution

2010
Cigarette smoke impairs airway epithelial barrier function and cell-cell contact recovery.
    The European respiratory journal, 2012, Volume: 39, Issue:2

    Topics: Cell Communication; Cell Division; Cells, Cultured; Electric Impedance; Electroporation; Enzyme Inhibitors; ErbB Receptors; Female; Humans; Male; Middle Aged; Permeability; Pulmonary Disease, Chronic Obstructive; Quinazolines; Respiratory Mucosa; Smoking; Tight Junctions; Tyrphostins; Wound Healing

2012
The phosphoinositide 3'-kinase p110δ modulates contractile protein production and IL-6 release in human airway smooth muscle.
    Journal of cellular physiology, 2012, Volume: 227, Issue:8

    Topics: Adenine; Adult; Aged; Aged, 80 and over; Asthma; Benzamides; Cells, Cultured; Chromones; Class I Phosphatidylinositol 3-Kinases; Contractile Proteins; Dioxoles; Female; Gene Expression Regulation; Humans; Interleukin-6; Lung; Male; Middle Aged; Morpholines; Muscle, Smooth; Phosphatidylinositol 3-Kinases; Pulmonary Disease, Chronic Obstructive; Quinazolines; Tissue Donors; Transforming Growth Factor beta1

2012
Corticosteroid insensitivity is reversed by formoterol via phosphoinositide-3-kinase inhibition.
    British journal of pharmacology, 2012, Volume: 167, Issue:4

    Topics: 1-Phosphatidylinositol 4-Kinase; Adenine; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists; Adult; Aged; Albuterol; Androstadienes; Asthma; Budesonide; Chromones; Dexamethasone; Drug Resistance; Ethanolamines; Female; Fluticasone; Formoterol Fumarate; Humans; Hydrogen Peroxide; Interleukin-8; Leukocytes, Mononuclear; Male; Middle Aged; Morpholines; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Quinazolines; Receptors, Adrenergic, beta-2; Salmeterol Xinafoate; U937 Cells; Young Adult

2012
Increased activation of fibrocytes in patients with chronic obstructive asthma through an epidermal growth factor receptor-dependent pathway.
    The Journal of allergy and clinical immunology, 2012, Volume: 129, Issue:5

    Topics: Acetylcysteine; ADAM Proteins; ADAM17 Protein; Adult; Antigens, CD34; Asthma; Blood Cells; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Collagen Type I; ErbB Receptors; Female; Fibroblasts; Follow-Up Studies; Gefitinib; Humans; Hydrogen Peroxide; Leukocyte Common Antigens; Male; Middle Aged; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Quinazolines; Respiratory Function Tests; Signal Transduction; Stem Cells; Tyrphostins

2012
Fatal interstitial lung disease associated with oral erlotinib therapy for lung cancer.
    BMC cancer, 2007, Aug-05, Volume: 7

    Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cause of Death; ErbB Receptors; Erlotinib Hydrochloride; Fatal Outcome; Humans; Lung Diseases, Interstitial; Lung Neoplasms; Male; Middle Aged; Protein Kinase Inhibitors; Pulmonary Disease, Chronic Obstructive; Quinazolines; Tomography, X-Ray Computed

2007