Page last updated: 2024-08-21

quinazolines and Pregnancy

quinazolines has been researched along with Pregnancy in 100 studies

Research

Studies (100)

TimeframeStudies, this research(%)All Research%
pre-199021 (21.00)18.7374
1990's4 (4.00)18.2507
2000's28 (28.00)29.6817
2010's44 (44.00)24.3611
2020's3 (3.00)2.80

Authors

AuthorsStudies
Bar-On, S; Haynes, RK; Lantsberg, D; Laskov, I; Oiknine-Djian, E; Panet, A; Wolf, DG1
Arima, S; Asano, D; Kaneko, Y; Kondo, R; Morita, A; Nagamitsu, T; Nakahara, T; Nakano, A; Sakamoto, K1
Elefant, E; Faure Bardon, V; Guilleminot, T; Lê, MP; Leruez-Ville, M; Peytavin, G; Stirnemann, J; Ville, Y1
Anaclerico, B; Andriani, A; Baldacci, E; Breccia, M; Cedrone, M; Cimino, G; Di Veroli, A; Latagliata, R; Mazzucconi, MG; Montanaro, M; Montefusco, E; Paoloni, F; Porrini, R; Rago, A; Santoro, C; Scaramucci, L; Spadea, A; Spirito, F; Villivà, N1
Diao, HL; Liao, HQ; Ma, N; Tian, L; Yang, H; Zhang, CJ1
Copello, GJ; De Fino, FT; Evelson, PA; Filia, MF; Marchini, T; Minoia, JM; Peroni, RN; Roma, MI; Rubio, MC1
Berveiller, P; Cornet, N; Mir, O; Vialard, F1
Brownfoot, F; Campbell, L; Ellett, L; Hannan, NJ; Hastie, R; Horne, AW; Kaitu'u-Lino, TJ; Lim, E; Sluka, P; Tong, S1
Baple, EL; Brooke, A; Derse-Anthony, C; Glod, J; Newbold, K; Osborne, N; Sturley, R; Thomas, N; Vaidya, B1
Bhattacharya, S; Colin Duncan, W; Doust, A; Horne, AW; Johns, TG; Krzys, N; Mollison, J; Neil, P; Robinson, M; Skubisz, MM; Tong, S; Wallace, E1
Chi, Y; Jiang, ZC1
Alvarez-Larrán, A; Besses, C; Cervantes, F1
Abe, N; Ishii, K; Mori, A; Morita, A; Nagamitsu, T; Nakahara, T; Sakamoto, K; Wada, Y1
Autry, AM1
Dimitriadis, E; Gao, Y; Greenall, SA; Horne, AW; Johns, TG; Kaitu'u-Lino, T; Menkhorst, E; Nilsson, UW; Saglam, B; Tong, S; Whitehead, C; Wilmann, T1
Critchley, HOD; Duncan, WC; Horne, AW; Johns, TG; Nilsson, UW; Skubisz, MM; Tong, S; Wallace, EM1
Gao, QS; Guo, Q; Hong, Y; Jin, JX; Jin, L; Kang, JD; Li, S; Yan, CG; Yin, XJ; Zhu, HY1
Abe, N; Ishii, K; Kurauchi, Y; Mori, A; Morita, A; Nagamitsu, T; Nakahara, T; Sakamoto, K2
Burghes, AH; Butchbach, ME; Gurney, ME; Singh, J1
Duncan, WC; Horne, AW; Johns, TG; Neil, P; Skubisz, MM; Tong, S; Wallace, EM1
Ayoubi, JM; Broutin, S; Couderc, LJ; Friard, S; Gil, S; Goetgheluck, J; Paci, A; Picone, O; Tcherakian, C1
Liu, Y; Wang, Y; Wu, W; Xu, Y; Zhang, H1
Horne, AW; Skubisz, MM; Tong, S1
Dong, Y; Guan, Z; Niu, B; Wang, J; Wang, X; Xu, L; Zhang, J; Zhang, T1
Griffiths, P; Lumley, S1
Bergmann, F; Griesshammer, M; Koschmieder, S; Kreher, S; Matzdorff, A; Ochsenreither, S; Pabinger, I; Petrides, PE; Riess, H; Tiede, A; Trappe, RU1
Bidart, JM; Broutin, S; Gil, S; Goffinet, F; Jovelet, C; Mir, O; Paci, A; Seck, A; Simasotchi, C1
Mishra, N; Nugent, WH; Strauss, JF; Walsh, SW1
Ishii, K; Mori, A; Nakahara, T; Nakano, A; Sakamoto, K; Ushikubo, H1
Gottesman, MM; Hall, MD; Kumar, JS; Madigan, JP; Simpson, RM; Wei, BR1
Broutin, S; Gil, S; Jovelet, C; Mir, O; Paci, A1
Bahsi, H; Chou, S; Hamilton, S; Haupt, VJ; Hutterer, C; Marschall, M; Naing, Z; Örfi, L; Örfi, Z; Rawlinson, W; Socher, E; Steingruber, M; Sticht, H; Thuma, N; Zeitträger, I1
Arima, S; Ishii, K; Mori, A; Morita, A; Nagamitsu, T; Nakahara, T; Sakamoto, K; Ushikubo, H1
Benveniste, EN; Dees, KJ; Gibson, SA; Hjelmeland, AB; McFarland, BC; Meares, GP; Nozell, SE; Rajbhandari, R; Rowse, AL1
Birgegård, G1
Cui, L; Dai, Z; Hu, GY; Jiang, DJ; Liu, SY; Xiao, J1
Chaffin, CL; Latham, KE; Lee, YS; Nyholt de Prada, JK; VandeVoort, CA1
Fujita, S; Harada, Y; Hata, A; Imai, Y; Ishihara, K; Katakami, N; Nishimura, T; Seo, R; Takeshim, Y; Tomii, K1
Bello López, JL; Pérez Encinas, MM; Quinteiro García, C; Rabuñal Martinez, MJ; Sobas, MA1
Hislop, AA; Ibe, BO; Longo, LD; Raj, JU; Sheng, L; Zhou, W1
Abe, N; Ishii, K; Nagamitsu, T; Nakahara, T; Ohta, H; Ozaki, H; Wada, Y1
De Keulenaer, GW; Doggen, K; Lemmens, K1
Bates, DO; Bills, VL; Harper, SJ; Jeffery, B; Neal, CR; Overton, TG; Salmon, AH; Soothill, PW1
Chua, KT; Lai, NL; Lee, CH; Liam, CK; Lim, BK; Pang, YK1
Finazzi, G1
Arola, M; Kähkönen, M; Lohi, O; Parto, K; Vettenranta, K; Vornanen, M1
Evens, A; Osborne, CK1
Arango, N; Bonilla, C; Cuello, J; Llinás, N; Rivas, G; Rubiano, J1
Cabot, RA; Johnson, CM; Park, KE1
Barnette, NK; Chai, KX; Chen, LM; Fu, YY; Nergard, JC; Wang, YL1
García-Sanchez, R; Plaza, S; Ramirez, G1
Abe, N; Ishii, K; Mori, A; Nagamitsu, T; Nakahara, T; Ozaki, H; Sakamoto, K; Wada, Y1
Giles, FJ; Tsimberidou, AM1
Schuster, L1
Araie, M; Goto, W; Hara, H; Ichikawa, M; Tanaka, E1
Campbell, PJ; Curtin, N; Green, AR; Vassiliou, GS1
Brychtova, Y; Doubek, M; Doubek, R; Janku, P; Mayer, J1
Abud, HE; Heath, JK; Watson, N1
Chaki, S; Funakoshi, T; Grottick, AJ; Hirota-Okuno, S; Iijima, M; Kanuma, K; Nishiguchi, M; Okuyama, S; Omodera, K; Sekiguchi, Y; Semple, G; Shimazaki, T; Thomsen, W; Tran, TA1
Fujii, N; Okabayashi, T; Suzutani, T; Yokosawa, N; Yokota, S1
Alkindi, S; Dennison, D; Pathare, A1
Clinton-Luke, P; Dreyfus, CF; Du, Y; Fischer, TZ; Lercher, LD1
Awooda, I; Barhoumi, R; Burghardt, RC; Mouneimne, Y; Safe, S1
Petrides, PE2
Boggess, KA; Dees, EC; Dorflinger, LJ; Graham, M; Harris, J; Humes, E; Kelly, H; O'Neil, BH; Spector, NL1
Reilly, JT1
Berveiller, P; Goffinet, F; Goldwasser, F; Mir, O; Pons, G; Ropert, S; Treluyer, JM1
Ballabh, P; Braun, A; Chander, P; Csiszar, A; Hu, F; Kocherlakota, P; Nedergaard, M; Siegel, D; Ungvari, Z; Xu, H1
Fregoni, V; Pavesi, L; Ponchio, L; Prada, GA; Sagrada, P; Zambelli, A1
Blumenfeld, M; Farrar, W; Landon, MB; Pant, S; Shapiro, CL1
Ambrosio, E; Azuara, MC; Fernandez, I; Montero, MT; Orensanz, LM1
Hodge, JV; Lubbe, WF1
Butters, L; Low, RA; Reid, JL; Rubin, PC1
Bernabé, J; Burvenich, C; Peeters, G; Vandeputte-Van Messom, G1
Decker, VL; Schwender, CF; Sunday, BR1
Davey, DA; Dommisse, J; Roos, PJ1
Fudenberg, HH; Hynes, JB; Tsang, KY1
Madörin, M; Matter, BE; Richardson, BP; Rüttimann, G; Schön, H; van Ryzin, RJ1
Ego, H; Fukuchi, I; Ishida, R; Kudo, Y; Ochiai, T; Yamamura, M1
Lubbe, WF1
Hibi, H; Miyake, K; Yamamoto, M1
Carter, DB; Hamilton, BJ; Im, HK; Im, WB; Jacobsen, EJ; Pregenzer, JF; TenBrink, RE; VonVoigtlander, PF1
Baba, A; Kawamura, N; Makino, H; Ohta, Y; Sohda, T; Taketomi, S1
Dukarm, RC; Morin, FC; Perry, BJ; Russell, JA; Steinhorn, RH1
Briere, J; Guilmin, F1
Tefferi, A; Wright, CA1
Bundred, N; Gilmore, AP; Korsmeyer, SJ; O'Hare, MJ; Ranger, AM; Streuli, CH; Valentijn, AJ; Wakeling, A; Wang, P1
Mukherjee, K; Sethi, N1
Anand, KK; Atal, CK; Ghatak, BJ; Gupta, OP1
Bhoola, R; Seedat, MA; Seedat, YK1
Hashimoto, J; Mitsuya, H; Miyake, K; Takaba, H; Yamamoto, M1
Kast, A; Kobayashi, S; Nishimura, M; Tsunenari, Y1
Duffy, GJ; Martin, F; O'Dwyer, WF1
Jönsson, NA; Mikiver, L; Selberg, U1
Saksena, SK; Somasekhara, S1
Magistretti, MJ; Setnikar, I1

Reviews

15 review(s) available for quinazolines and Pregnancy

ArticleYear
[Treatment of essential thrombocythemia].
    Medicina clinica, 2013, Sep-21, Volume: 141, Issue:6

    Topics: Adult; Age Factors; Aged; Anticoagulants; Aspirin; Cell Transformation, Neoplastic; Disease Progression; Female; Hemorrhage; Heparin, Low-Molecular-Weight; Humans; Hydroxyurea; Intraoperative Complications; Janus Kinase 2; Leukemia, Myeloid, Acute; Life Expectancy; Male; Middle Aged; Mutation, Missense; Platelet Aggregation Inhibitors; Point Mutation; Pregnancy; Pregnancy Complications, Hematologic; Primary Myelofibrosis; Quinazolines; Risk Factors; Thrombocythemia, Essential; Thrombophilia

2013
Efficacy and safety of gefitinib during pregnancy: case report and literature review.
    Lung cancer (Amsterdam, Netherlands), 2014, Volume: 85, Issue:3

    Topics: Adult; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Erlotinib Hydrochloride; Fatal Outcome; Female; Humans; Lung Neoplasms; Mutation; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Outcome; Protein Kinase Inhibitors; Quinazolines; Radiography, Thoracic; Tomography Scanners, X-Ray Computed

2014
Cytomegalovirus.
    Current opinion in infectious diseases, 2014, Volume: 27, Issue:6

    Topics: Acetates; Antiviral Agents; Benzimidazoles; Bone Marrow Transplantation; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Transmission, Infectious; Double-Blind Method; Female; Ganciclovir; Humans; Male; Organ Transplantation; Organophosphonates; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Infectious; Quinazolines; Randomized Controlled Trials as Topic; Ribonucleosides

2014
[Tyrosine kinase inhibitors and pregnancy: A risk to the fetus?].
    Bulletin du cancer, 2016, Volume: 103, Issue:5

    Topics: Abnormalities, Drug-Induced; Adult; Antineoplastic Agents; Dasatinib; Erlotinib Hydrochloride; Female; Fetus; Gefitinib; Humans; Imatinib Mesylate; Lapatinib; Maternal Age; Placenta; Pregnancy; Pregnancy Complications, Neoplastic; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Quinazolines; Risk

2016
Long-term management of thrombocytosis in essential thrombocythaemia.
    Annals of hematology, 2009, Volume: 88, Issue:1

    Topics: Algorithms; Antineoplastic Agents; Aspirin; Female; Fibrinolytic Agents; Humans; Hydroxyurea; Interferon-alpha; Janus Kinase 2; Pregnancy; PubMed; Quinazolines; Randomized Controlled Trials as Topic; Thrombocythemia, Essential; Thrombocytosis

2009
Anagrelide treatment in early pregnancy in a patient with JAK2V617F-positive essential thrombocythemia: case report and literature review.
    Acta haematologica, 2009, Volume: 122, Issue:4

    Topics: Adult; Amino Acid Substitution; Female; Fibrinolytic Agents; Humans; Infant, Newborn; Janus Kinase 2; Point Mutation; Pregnancy; Pregnancy Complications, Hematologic; Pregnancy Outcome; Quinazolines; Thrombocythemia, Essential

2009
How to manage essential thrombocythemia.
    Leukemia, 2012, Volume: 26, Issue:5

    Topics: Female; Heparin, Low-Molecular-Weight; Humans; Hydroxyurea; Interferon-alpha; Pregnancy; Pregnancy Complications, Hematologic; Quinazolines; Risk Factors; Thrombocythemia, Essential

2012
[Management of patients with essential thrombocythemia].
    Medicina clinica, 2013, Mar-16, Volume: 140, Issue:6

    Topics: Adult; Aged; Bone Marrow; Cytostatic Agents; Disease Management; Female; Genetic Predisposition to Disease; Hemorrhage; Humans; Interferon-alpha; Janus Kinase 2; Lactation; Male; Middle Aged; Platelet Aggregation Inhibitors; Point Mutation; Pregnancy; Pregnancy Complications, Hematologic; Quinazolines; Thrombocythemia, Essential; Thrombophilia

2013
Essential thrombocythemia (ET): moving from palliation to cure.
    Hematology (Amsterdam, Netherlands), 2002, Volume: 7, Issue:6

    Topics: Female; Humans; Hydroxyurea; Interferon alpha-2; Interferon-alpha; Male; Palliative Care; Pregnancy; Pregnancy Complications, Hematologic; Quinazolines; Recombinant Proteins; Thrombocythemia, Essential

2002
Management of the myeloproliferative disorders : distinguishing data from dogma.
    The hematology journal : the official journal of the European Haematology Association, 2004, Volume: 5 Suppl 3

    Topics: Abnormalities, Drug-Induced; Adult; Aged; Anticoagulants; Contraindications; Female; Humans; Hydroxyurea; Interferon-alpha; Male; Middle Aged; Myeloproliferative Disorders; Phlebotomy; Polycythemia Vera; Pregnancy; Pregnancy Complications, Hematologic; Prognosis; Quinazolines; Randomized Controlled Trials as Topic; Thrombocythemia, Essential; Thrombophilia

2004
Anagrelide: what was new in 2004 and 2005?
    Seminars in thrombosis and hemostasis, 2006, Volume: 32, Issue:4 Pt 2

    Topics: Antineoplastic Agents; Aspirin; Blood Platelets; Clinical Trials, Phase III as Topic; Drug Therapy, Combination; Female; Fibrinolytic Agents; Hemorrhage; History, 21st Century; Humans; Hydroxyurea; Male; Megakaryocytes; Platelet Aggregation Inhibitors; Pregnancy; Pregnancy Complications, Hematologic; Quinazolines; Randomized Controlled Trials as Topic; Signal Transduction; Thrombocythemia, Essential

2006
[Primary thrombocythemia: diagnosis and therapy].
    Medizinische Klinik (Munich, Germany : 1983), 2006, Aug-15, Volume: 101, Issue:8

    Topics: Adult; Aged; Aspirin; Child; Diagnosis, Differential; Drug Therapy, Combination; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Hydroxyurea; Immunologic Factors; Interferon-alpha; Male; Mutation; Platelet Aggregation Inhibitors; Platelet Count; Pregnancy; Pregnancy Complications, Hematologic; Primary Prevention; Prospective Studies; Quinazolines; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Thrombocythemia, Essential; Time Factors

2006
Emerging therapeutic options for breast cancer chemotherapy during pregnancy.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Volume: 19, Issue:4

    Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Docetaxel; Female; Humans; Lapatinib; Oligohydramnios; Paclitaxel; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Quinazolines; Receptor, ErbB-2; Taxoids; Trastuzumab; Vinblastine; Vinorelbine

2008
Management of patients with essential thrombocythemia: current concepts and perspectives.
    Pathologie-biologie, 2001, Volume: 49, Issue:2

    Topics: Adult; Aged; Aspirin; Case Management; Clinical Trials as Topic; Diagnosis, Differential; Disease Progression; Female; Hemorrhagic Disorders; Humans; Hydroxyurea; Interferons; Leukemia; Male; Middle Aged; Pipobroman; Platelet Aggregation Inhibitors; Platelet Count; Pregnancy; Pregnancy Complications, Hematologic; Prospective Studies; Quinazolines; Risk; Safety; Thrombocythemia, Essential; Thrombophilia

2001
A single institutional experience with 43 pregnancies in essential thrombocythemia.
    European journal of haematology, 2001, Volume: 66, Issue:3

    Topics: Abortion, Induced; Abortion, Spontaneous; Abruptio Placentae; Adult; Anticoagulants; Aspirin; Busulfan; Erythromelalgia; Female; Fetal Death; Follow-Up Studies; Heparin; Humans; Hydroxyurea; Migraine Disorders; Obstetric Labor, Premature; Phosphorus Radioisotopes; Platelet Aggregation Inhibitors; Platelet Count; Plateletpheresis; Pregnancy; Pregnancy Complications, Hematologic; Pregnancy Outcome; Pregnancy Trimester, First; Pregnancy, Ectopic; Pregnancy, High-Risk; Quinazolines; Retrospective Studies; Risk; Thrombocythemia, Essential; Uterine Hemorrhage

2001

Trials

4 trial(s) available for quinazolines and Pregnancy

ArticleYear
Gefitinib and Methotrexate to Treat Ectopic Pregnancies with a Pre-Treatment Serum hCG 1000-10,000 IU/L: Phase II Open Label, Single Arm Multi-Centre Trial.
    EBioMedicine, 2018, Volume: 33

    Topics: Administration, Intranasal; Administration, Oral; Adult; Chorionic Gonadotropin; Drug Therapy, Combination; Female; Gefitinib; Humans; Methotrexate; Pregnancy; Pregnancy, Ectopic; Quinazolines; Treatment Outcome

2018
Combination gefitinib and methotrexate compared with methotrexate alone to treat ectopic pregnancy.
    Obstetrics and gynecology, 2013, Volume: 122, Issue:4

    Topics: Abortifacient Agents, Nonsteroidal; Adult; Antineoplastic Agents; Drug Therapy, Combination; Female; Gefitinib; Humans; Injections, Intramuscular; Methotrexate; Pregnancy; Pregnancy, Ectopic; Quinazolines

2013
Comparison of the effectiveness of placebo and alpha-blocker therapy for the treatment of idiopathic oligozoospermia.
    Fertility and sterility, 1995, Volume: 63, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adult; Double-Blind Method; Female; Humans; Infertility, Male; Male; Oligospermia; Placebos; Pregnancy; Quinazolines; Sperm Count; Sperm Motility

1995
The effects of a new diuretic (metolazone) on pre-eclamptic toxaemia of pregnancy.
    Journal of the Irish Medical Association, 1972, Dec-23, Volume: 65, Issue:24

    Topics: Administration, Oral; Adult; Diuretics; Evaluation Studies as Topic; Female; Humans; Pre-Eclampsia; Pregnancy; Quinazolines; Sulfonamides

1972

Other Studies

81 other study(ies) available for quinazolines and Pregnancy

ArticleYear
Artemisone demonstrates synergistic antiviral activity in combination with approved and experimental drugs active against human cytomegalovirus.
    Antiviral research, 2019, Volume: 172

    Topics: Acetates; Antiviral Agents; Artemisinins; Benzimidazoles; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Interactions; Drug Synergism; Drugs, Investigational; Female; Ganciclovir; Humans; Organ Culture Techniques; Organophosphonates; Placenta; Pregnancy; Quinazolines; Ribonucleosides

2019
Changes in components of the neurovascular unit in the retina in a rat model of retinopathy of prematurity.
    Cell and tissue research, 2020, Volume: 379, Issue:3

    Topics: Animals; Disease Models, Animal; Female; Phenylurea Compounds; Pregnancy; Protein Kinase Inhibitors; Quinazolines; Rats; Rats, Sprague-Dawley; Retina; Retinal Neovascularization; Retinopathy of Prematurity; Vascular Endothelial Growth Factor A

2020
Placental transfer of Letermovir & Maribavir in the ex vivo human cotyledon perfusion model. New perspectives for in utero treatment of congenital cytomegalovirus infection.
    PloS one, 2020, Volume: 15, Issue:4

    Topics: Acetates; Adult; Antiviral Agents; Benzimidazoles; Chromatography, Liquid; Cytomegalovirus Infections; Female; Humans; Kinetics; Maternal-Fetal Exchange; Models, Biological; Perfusion; Placenta; Pregnancy; Quinazolines; Ribonucleosides; Tandem Mass Spectrometry

2020
Anagrelide in Essential Thrombocythemia (ET): Results from 150 patients over 25 years by the "Ph1-negative Myeloproliferative Neoplasms Latium Group".
    European journal of haematology, 2020, Volume: 105, Issue:3

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anemia; Disease Management; Disease Susceptibility; Drug Substitution; Female; Follow-Up Studies; Health Care Surveys; Humans; Italy; Male; Middle Aged; Pregnancy; Pregnancy Complications, Hematologic; Prognosis; Quinazolines; Retreatment; Retrospective Studies; Thrombocythemia, Essential; Thrombosis; Treatment Outcome; Young Adult

2020
[Methyltransferase inhibitor BIX01294 promotes the migration and inhibits decidualization of mouse uterine stromal cells in vitro].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2017, Jun-20, Volume: 37, Issue:6

    Topics: Animals; Azepines; Cell Movement; Cells, Cultured; Decidua; Embryo Implantation; Endometrium; Female; Histone-Lysine N-Methyltransferase; Mice; Pregnancy; Quinazolines; Stromal Cells

2017
Induction of ABCG2/BCRP restricts the distribution of zidovudine to the fetal brain in rats.
    Toxicology and applied pharmacology, 2017, 09-01, Volume: 330

    Topics: Animals; Anti-HIV Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Biological Availability; Brain; Female; Fetus; Gefitinib; Lipid Peroxidation; Mitochondria; Pregnancy; Quinazolines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Inhibitors; Zidovudine

2017
Is anagrelide safe during pregnancy?
    Journal of gynecology obstetrics and human reproduction, 2017, Volume: 46, Issue:9

    Topics: Abortion, Spontaneous; Adult; Female; Humans; Platelet Aggregation Inhibitors; Pregnancy; Pregnancy Complications, Hematologic; Quinazolines; Thrombocythemia, Essential; Uterine Hemorrhage

2017
Vinorelbine Potently Induces Placental Cell Death, Does Not Harm Fertility and is a Potential Treatment for Ectopic Pregnancy.
    EBioMedicine, 2018, Volume: 29

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Death; Cell Line; Cell Proliferation; Cell Survival; Disease Models, Animal; Female; Fertility; Gefitinib; Heterografts; Humans; Methotrexate; Mice; Microtubules; Miosis; Placenta; Pregnancy; Pregnancy, Ectopic; Quinazolines; Trophoblasts; Vinblastine; Vinorelbine

2018
Pregnancy on vandetanib in metastatic medullary thyroid carcinoma associated with multiple endocrine neoplasia type 2B.
    Clinical endocrinology, 2018, Volume: 88, Issue:5

    Topics: Adult; Carcinoma, Neuroendocrine; Female; Humans; Multiple Endocrine Neoplasia Type 2a; Mutation, Missense; Neoplasm Metastasis; Piperidines; Pregnancy; Quinazolines; Thyroid Neoplasms; Young Adult

2018
[Data review and analysis of 22 cases of gastric cancer associated with pregnancy].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2018, Aug-23, Volume: 40, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Signet Ring Cell; Cesarean Section; China; Female; Fluorouracil; Gastrectomy; Humans; Irinotecan; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Palliative Care; Pregnancy; Pregnancy Complications, Neoplastic; Prognosis; Quinazolines; Stomach Neoplasms; Survival Rate; Thiophenes

2018
KRN633, an inhibitor of vascular endothelial growth factor receptor tyrosine kinase, induces intrauterine growth restriction in mice.
    Birth defects research. Part B, Developmental and reproductive toxicology, 2013, Volume: 98, Issue:4

    Topics: Animals; Animals, Newborn; Female; Fetal Growth Retardation; Intestine, Small; Kidney; Lymphoid Tissue; Male; Mice; Pancreas; Phenylurea Compounds; Placenta; Pregnancy; Protein Kinase Inhibitors; Quinazolines; Receptors, Vascular Endothelial Growth Factor

2013
Medical treatment of ectopic pregnancy: is there something new?
    Obstetrics and gynecology, 2013, Volume: 122, Issue:4

    Topics: Abortifacient Agents, Nonsteroidal; Animals; Antineoplastic Agents; ErbB Receptors; Female; Gefitinib; Humans; Methotrexate; Placenta; Pregnancy; Pregnancy, Ectopic; Quinazolines

2013
Effects of gefitinib, an epidermal growth factor receptor inhibitor, on human placental cell growth.
    Obstetrics and gynecology, 2013, Volume: 122, Issue:4

    Topics: Abortifacient Agents, Nonsteroidal; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Evaluation, Preclinical; Drug Therapy, Combination; ErbB Receptors; Female; Gefitinib; Humans; Methotrexate; Mice; Mice, SCID; Placenta; Pregnancy; Pregnancy Trimester, First; Pregnancy, Ectopic; Quinazolines

2013
CUDC-101, a histone deacetylase inhibitor, improves the in vitro and in vivo developmental competence of somatic cell nuclear transfer pig embryos.
    Theriogenology, 2014, Mar-01, Volume: 81, Issue:4

    Topics: Animals; Cellular Reprogramming; Embryo Transfer; Embryo, Mammalian; Embryonic Development; Enzyme Inhibitors; Female; Histones; Hydroxamic Acids; Microscopy, Fluorescence; Pregnancy; Quinazolines; Swine

2014
Effects of pre- and post-natal treatment with KRN633, an inhibitor of vascular endothelial growth factor receptor tyrosine kinase, on retinal vascular development and patterning in mice.
    Experimental eye research, 2014, Volume: 120

    Topics: Administration, Oral; Animals; Animals, Newborn; Female; Fluorescein Angiography; Fluorescent Antibody Technique, Indirect; In Situ Hybridization; Male; Mice; Mice, Inbred ICR; Phenylurea Compounds; Platelet Endothelial Cell Adhesion Molecule-1; Pregnancy; Prenatal Exposure Delayed Effects; Quinazolines; Retinal Neovascularization; Retinal Vessels; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2

2014
The effect of diet on the protective action of D156844 observed in spinal muscular atrophy mice.
    Experimental neurology, 2014, Volume: 256

    Topics: Animals; Brain; Diet; Disease Models, Animal; Female; Male; Mice; Muscular Atrophy, Spinal; Pregnancy; Prenatal Exposure Delayed Effects; Quinazolines; Severity of Illness Index; SMN Complex Proteins; Spinal Cord; Treatment Outcome

2014
Combination gefitinib and methotrexate treatment for non-tubal ectopic pregnancies: a case series.
    Human reproduction (Oxford, England), 2014, Volume: 29, Issue:7

    Topics: Abortifacient Agents, Nonsteroidal; Acneiform Eruptions; Adult; Cesarean Section; Chorionic Gonadotropin; Fallopian Tubes; Female; Gefitinib; Humans; Methotrexate; Pregnancy; Pregnancy Outcome; Pregnancy, Ectopic; Quinazolines; Ultrasonography, Prenatal; Young Adult

2014
Treatment of mid-pregnant mice with KRN633, an inhibitor of vascular endothelial growth factor receptor tyrosine kinase, induces abnormal retinal vascular patterning in their newborn pups.
    Birth defects research. Part B, Developmental and reproductive toxicology, 2014, Volume: 101, Issue:4

    Topics: Animals; Animals, Newborn; Female; Fetal Growth Retardation; Mice; Mice, Inbred ICR; Neovascularization, Physiologic; Phenylurea Compounds; Pregnancy; Quinazolines; Receptor, Platelet-Derived Growth Factor beta; Receptors, Vascular Endothelial Growth Factor; Retinal Vessels

2014
Dysregulated activation of c-Src in gestational trophoblastic disease contributes to its aggressive progression.
    Placenta, 2014, Volume: 35, Issue:10

    Topics: Benzodioxoles; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chorionic Gonadotropin; Enzyme Inhibitors; Female; Gestational Trophoblastic Disease; Humans; Pregnancy; Pyrimidines; Quinazolines; src-Family Kinases

2014
Molecular diagnostics and therapeutics for ectopic pregnancy.
    Molecular human reproduction, 2015, Volume: 21, Issue:2

    Topics: Animals; Biomarkers; Female; Gefitinib; Humans; Methotrexate; Pregnancy; Pregnancy, Ectopic; Quinazolines

2015
Raltitrexed's effect on the development of neural tube defects in mice is associated with DNA damage, apoptosis, and proliferation.
    Molecular and cellular biochemistry, 2015, Volume: 398, Issue:1-2

    Topics: Animals; Apoptosis; Blotting, Western; Cell Proliferation; Deoxyuracil Nucleotides; DNA Damage; Embryo, Mammalian; Female; Folic Acid Antagonists; Gestational Age; Histones; Injections, Intraperitoneal; Male; Mice, Inbred C57BL; Neural Tube Defects; Phosphorylation; Pregnancy; Protein Subunits; Quinazolines; Replication Protein A; Thiophenes; Thymidine Monophosphate; Thymidylate Synthase

2015
Prophylaxis and management of venous thromboembolism in patients with myeloproliferative neoplasms: consensus statement of the Haemostasis Working Party of the German Society of Hematology and Oncology (DGHO), the Austrian Society of Hematology and Oncolo
    Annals of hematology, 2014, Volume: 93, Issue:12

    Topics: Anticoagulants; Disease Susceptibility; Drug Interactions; Female; Hemorrhage; Heparin, Low-Molecular-Weight; Humans; Hydroxyurea; Incidence; Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative; Male; Myeloproliferative Disorders; Phlebotomy; Platelet Aggregation Inhibitors; Postoperative Complications; Pregnancy; Pregnancy Complications, Hematologic; Preoperative Care; Protein Kinase Inhibitors; Quinazolines; Secondary Prevention; Thrombophilia; Venous Thromboembolism; von Willebrand Diseases

2014
Variation in transplacental transfer of tyrosine kinase inhibitors in the human perfused cotyledon model.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:7

    Topics: Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Erlotinib Hydrochloride; Female; Fetus; Gefitinib; Humans; Imatinib Mesylate; Lung Neoplasms; Maternal-Fetal Exchange; Mutation; Perfusion; Placenta; Pregnancy; Protein Kinase Inhibitors; Quinazolines; Tissue Distribution

2015
Matrix Metalloproteinase 1 Causes Vasoconstriction and Enhances Vessel Reactivity to Angiotensin II via Protease-Activated Receptor 1.
    Reproductive sciences (Thousand Oaks, Calif.), 2016, Volume: 23, Issue:4

    Topics: Adult; Angiotensin II; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; Matrix Metalloproteinase 1; Omentum; Organ Culture Techniques; Pre-Eclampsia; Pregnancy; Pyrroles; Quinazolines; Receptor, PAR-1; Vasoconstriction; Young Adult

2016
Short-term treatment with VEGF receptor inhibitors induces retinopathy of prematurity-like abnormal vascular growth in neonatal rats.
    Experimental eye research, 2016, Volume: 143

    Topics: Animals; Animals, Newborn; Axitinib; Disease Models, Animal; Female; Fluorescent Antibody Technique, Indirect; Imidazoles; Indazoles; Microscopy, Fluorescence; Phenylurea Compounds; Pregnancy; Protein-Tyrosine Kinases; Quinazolines; Rats; Rats, Sprague-Dawley; Retinal Neovascularization; Retinal Vessels; Retinopathy of Prematurity; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2

2016
Bioluminescent imaging of ABCG2 efflux activity at the blood-placenta barrier.
    Scientific reports, 2016, Feb-08, Volume: 6

    Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Benzothiazoles; Biological Transport; Blood-Brain Barrier; Blotting, Western; Cells, Cultured; Choriocarcinoma; Female; Flow Cytometry; Gefitinib; Image Processing, Computer-Assisted; Luciferases, Firefly; Luminescent Agents; Luminescent Measurements; Male; Mice; Mice, Transgenic; Placenta; Pregnancy; Quinazolines; Tissue Distribution

2016
The chemical class of quinazoline compounds provides a core structure for the design of anticytomegaloviral kinase inhibitors.
    Antiviral research, 2016, Volume: 134

    Topics: Antiviral Agents; Cells, Cultured; Cytomegalovirus; Drug Design; Drug Resistance, Viral; Female; Fibroblasts; Humans; Models, Molecular; Molecular Docking Simulation; Placenta; Pregnancy; Protein Kinase Inhibitors; Quinazolines; Viral Proteins; Virus Replication

2016
A delay in vascularization induces abnormal astrocyte proliferation and migration in the mouse retina.
    Developmental dynamics : an official publication of the American Association of Anatomists, 2017, Volume: 246, Issue:3

    Topics: Animals; Astrocytes; Cell Movement; Cell Proliferation; Endothelial Cells; Female; Hypoxia; Immunohistochemistry; In Situ Hybridization; Male; Mice; Phenylurea Compounds; Pregnancy; Quinazolines; Retina; Vascular Endothelial Growth Factor A

2017
Protein kinase CK2 is important for the function of glioblastoma brain tumor initiating cells.
    Journal of neuro-oncology, 2017, Volume: 132, Issue:2

    Topics: AC133 Antigen; Animals; Brain Neoplasms; Casein Kinase II; Cell Line, Tumor; Cell Proliferation; Embryo, Mammalian; Enzyme Inhibitors; Female; Gefitinib; Glioblastoma; Humans; Mice; Mice, Inbred C57BL; Mice, Nude; Naphthyridines; Neoplastic Stem Cells; Phenazines; Pregnancy; Quinazolines; RNA, Small Interfering; Signal Transduction; Xenograft Model Antitumor Assays

2017
Rutaecarpine inhibits hypoxia/reoxygenation-induced apoptosis in rat hippocampal neurons.
    Neuropharmacology, 2008, Volume: 55, Issue:8

    Topics: Animals; Apoptosis; Caspase 3; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Female; Hippocampus; Hypoxia; In Situ Nick-End Labeling; Indole Alkaloids; Neural Inhibition; Neurons; Oxidative Stress; Oxygen; Pregnancy; Quinazolines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Vasodilator Agents

2008
Role for cumulus cell-produced EGF-like ligands during primate oocyte maturation in vitro.
    American journal of physiology. Endocrinology and metabolism, 2009, Volume: 296, Issue:5

    Topics: Amphiregulin; Animals; Betacellulin; Cumulus Cells; EGF Family of Proteins; Embryonic Development; Enzyme Inhibitors; Epidermal Growth Factor; Epiregulin; ErbB Receptors; Female; Fertilization in Vitro; Glycoproteins; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Macaca mulatta; Oocytes; Phosphorylation; Pregnancy; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tyrphostins

2009
[A case of lung cancer combined with pregnancy; dramatically deteriorating condition after caesarian section].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2009, Volume: 47, Issue:7

    Topics: Adenocarcinoma; Adult; Antineoplastic Agents; Cesarean Section; Fatal Outcome; Female; Gefitinib; Humans; Lung Neoplasms; Pregnancy; Pregnancy Complications, Neoplastic; Quinazolines

2009
Role of epidermal growth factor receptor in ovine fetal pulmonary vascular remodeling following exposure to high altitude long-term hypoxia.
    High altitude medicine & biology, 2009,Winter, Volume: 10, Issue:4

    Topics: Actins; Altitude; Animals; Cell Proliferation; Cells, Cultured; ErbB Receptors; Female; Fetal Hypoxia; Muscle, Smooth, Vascular; Pregnancy; Proliferating Cell Nuclear Antigen; Pulmonary Artery; Quinazolines; Sheep, Domestic; Tyrphostins

2009
Effects of KRN633, an inhibitor of vascular endothelial growth factor receptor-2 tyrosine kinase, on vascular development of placenta and fetus of mid-pregnancy in mice.
    Journal of pharmacological sciences, 2010, Volume: 112, Issue:3

    Topics: Animals; Female; Fetal Growth Retardation; Fetus; Mice; Mice, Inbred ICR; Phenylurea Compounds; Placenta; Pregnancy; Pregnancy Trimester, Second; Protein Kinase Inhibitors; Quinazolines; Vascular Endothelial Growth Factor Receptor-2

2010
Activation of the neuregulin/ErbB system during physiological ventricular remodeling in pregnancy.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 300, Issue:3

    Topics: Animals; Female; Genes, erbB; Lapatinib; Mice; Mice, Inbred C57BL; Neuregulin-1; Phosphorylation; Pregnancy; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinazolines; Rats; Rats, Sprague-Dawley; Ventricular Function, Left; Ventricular Remodeling

2011
Impaired vascular permeability regulation caused by the VEGF₁₆₅b splice variant in pre-eclampsia.
    BJOG : an international journal of obstetrics and gynaecology, 2011, Volume: 118, Issue:10

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bevacizumab; Biological Assay; Capillary Permeability; Female; Humans; Membrane Proteins; Pre-Eclampsia; Pregnancy; Quinazolines; Ranidae; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1

2011
Successful pregnancy with epidermal growth factor receptor tyrosine kinase inhibitor treatment of metastatic lung adenocarcinoma presenting with respiratory failure.
    Lung cancer (Amsterdam, Netherlands), 2011, Volume: 74, Issue:2

    Topics: Adenocarcinoma; Adult; Disease Progression; ErbB Receptors; Erlotinib Hydrochloride; Female; Gefitinib; Humans; Lung Neoplasms; Lymphangitis; Lymphatic Metastasis; Neoplasm Staging; Pleural Effusion, Malignant; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Trimester, Third; Quinazolines; Remission Induction; Respiratory Insufficiency; Sequence Deletion; Term Birth

2011
Recurrent congenital fibrosarcoma with heart metastases.
    Journal of pediatric hematology/oncology, 2012, Volume: 34, Issue:5

    Topics: Erlotinib Hydrochloride; Female; Fibrosarcoma; Heart Neoplasms; Humans; Infant; Oncogene Proteins, Fusion; Pregnancy; Protein Kinase Inhibitors; Quinazolines; Recurrence

2012
Select interviews from the 2011 San Antonio Breast Cancer Symposium (SABCS) and American Society of Hematology (ASH) Annual Meeting.
    Oncology (Williston Park, N.Y.), 2011, Volume: 25, Issue:14

    Topics: Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Breast Neoplasms; Cyclophosphamide; Dacarbazine; Doxorubicin; Female; Fertility Preservation; Humans; Lapatinib; Lymphoma; Molecular Targeted Therapy; Prednisone; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Outcome; Quinazolines; Receptor, ErbB-2; Rituximab; Trastuzumab; Vinblastine; Vincristine

2011
Use of erlotinib throughout pregnancy: a case-report of a patient with metastatic lung adenocarcinoma.
    Lung cancer (Amsterdam, Netherlands), 2012, Volume: 77, Issue:2

    Topics: Adenocarcinoma; Adult; Antineoplastic Agents; Base Sequence; ErbB Receptors; Erlotinib Hydrochloride; Female; Humans; Lung Neoplasms; Mutation; Neoplasm Metastasis; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Outcome; Protein Kinase Inhibitors; Quinazolines; Treatment Outcome

2012
IVMBIX-01294, an inhibitor of the histone methyltransferase EHMT2, disrupts histone H3 lysine 9 (H3K9) dimethylation in the cleavage-stage porcine embryo.
    Reproduction, fertility, and development, 2012, Volume: 24, Issue:6

    Topics: Animals; Azepines; Cleavage Stage, Ovum; Dose-Response Relationship, Drug; Embryo Culture Techniques; Embryo Transfer; Embryo, Mammalian; Embryonic Development; Enzyme Inhibitors; Female; Fertilization in Vitro; Gene Expression Regulation, Developmental; Histone-Lysine N-Methyltransferase; Histones; Lysine; Methylation; Pregnancy; Pregnancy Rate; Quinazolines; RNA, Messenger; Swine; Time Factors; Transcription, Genetic

2012
Proteasome inhibition augments cigarette smoke-induced GM-CSF expression in trophoblast cells via the epidermal growth factor receptor.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Blotting, Western; Cell Line; Enzyme-Linked Immunosorbent Assay; ErbB Receptors; Female; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Intercellular Signaling Peptides and Proteins; Leupeptins; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 3; Nicotiana; Phosphorylation; Pregnancy; Proteasome Inhibitors; Quinazolines; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Smoke; Trophoblasts; Tyrphostins

2012
Role of vascular endothelial growth factor in maintenance of pregnancy in mice.
    Endocrinology, 2013, Volume: 154, Issue:2

    Topics: Animals; Corpus Luteum; Female; Mice; Mice, Inbred ICR; Parturition; Phenylurea Compounds; Pregnancy; Progesterone; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Vascular Endothelial Growth Factor A

2013
Highlights of the 11th Congress of the International Headache Society, held September 13-16, 2003, in Rome, Italy. Updating the headache classification system.
    Drug news & perspectives, 2003, Volume: 16, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Botulinum Toxins, Type A; Clinical Trials as Topic; Female; Headache; Humans; Mutation; Piperazines; Pregnancy; Quinazolines; Serotonin Receptor Agonists; Ubiquinone

2003
Bunazosin hydrochloride reduces glutamate-induced neurotoxicity in rat primary retinal cultures.
    Brain research, 2004, Apr-02, Volume: 1003, Issue:1-2

    Topics: Animals; Brain; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Female; Glutamic Acid; Pregnancy; Protein Binding; Quinazolines; Rats; Rats, Wistar; Retina

2004
Anagrelide therapy in pregnancy: report of a case of essential thrombocythemia.
    Annals of hematology, 2004, Volume: 83, Issue:11

    Topics: Adult; Female; Humans; Pregnancy; Pregnancy Complications, Hematologic; Quinazolines; Thrombocythemia, Essential

2004
Growth of intestinal epithelium in organ culture is dependent on EGF signalling.
    Experimental cell research, 2005, Feb-15, Volume: 303, Issue:2

    Topics: Animals; Apoptosis; Body Patterning; Cell Proliferation; Enzyme Inhibitors; Epidermal Growth Factor; Epithelium; ErbB Receptors; Female; Intestines; Mice; Mice, Inbred ICR; Organ Culture Techniques; Pregnancy; Quinazolines; Signal Transduction; Tyrphostins

2005
Anxiolytic- and antidepressant-like profile of ATC0065 and ATC0175: nonpeptidic and orally active melanin-concentrating hormone receptor 1 antagonists.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 313, Issue:2

    Topics: Administration, Oral; Animals; Anti-Anxiety Agents; Antidepressive Agents; CHO Cells; Cricetinae; Cyclohexylamines; Dose-Response Relationship, Drug; Female; Humans; Male; Mice; Mice, Inbred ICR; Pregnancy; Protein Binding; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Somatostatin; Stress, Physiological

2005
Induction of suppressor of cytokine signaling-3 by herpes simplex virus type 1 confers efficient viral replication.
    Virology, 2005, Jul-20, Volume: 338, Issue:1

    Topics: Amnion; Base Sequence; Cell Line; DNA-Binding Proteins; Enzyme Inhibitors; Female; Herpesvirus 1, Human; Humans; Janus Kinase 3; Oligodeoxyribonucleotides, Antisense; Pregnancy; Protein-Tyrosine Kinases; Quinazolines; Repressor Proteins; Signal Transduction; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; T-Lymphocytes; Trans-Activators; Transcription Factors; Transfection; U937 Cells; Virus Replication

2005
Successful outcome with anagrelide in pregnancy.
    Annals of hematology, 2005, Volume: 84, Issue:11

    Topics: Adult; Blood Cell Count; Female; Humans; Platelet Aggregation Inhibitors; Pregnancy; Pregnancy Complications, Hematologic; Quinazolines; Splenomegaly; Thrombocytosis

2005
Distinct effects of p75 in mediating actions of neurotrophins on basal forebrain oligodendrocytes.
    Molecular and cellular neurosciences, 2006, Volume: 31, Issue:2

    Topics: Animals; Brain-Derived Neurotrophic Factor; Carbazoles; Enzyme Inhibitors; Female; Indole Alkaloids; Mice; Mice, Inbred C57BL; Mice, Knockout; Myelin Basic Protein; Nerve Growth Factor; Neurotrophin 3; Oligodendroglia; Pregnancy; Prosencephalon; Quinazolines; Rats; Rats, Sprague-Dawley; Receptor, Nerve Growth Factor; Receptor, trkA

2006
Effects of benzo-a-pyrene on oxytocin-induced Ca2+ oscillations in myometrial cells.
    Toxicology letters, 2006, Aug-20, Volume: 165, Issue:2

    Topics: Adult; Benzo(a)pyrene; Calcium; Calcium Signaling; Carcinogens, Environmental; Cells, Cultured; Dose-Response Relationship, Drug; Drug Antagonism; Drug Combinations; Enzyme Inhibitors; Epidermal Growth Factor; Female; Genistein; Humans; Myometrium; Oxytocin; Pregnancy; Protein-Tyrosine Kinases; Quinazolines; Tetraethylammonium; Tyrphostins

2006
Delivery of a healthy baby after first-trimester maternal exposure to lapatinib.
    Clinical breast cancer, 2006, Volume: 7, Issue:4

    Topics: Adult; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Ductal, Breast; Female; Humans; Infant, Newborn; Lapatinib; Live Birth; Neoplasm Metastasis; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Trimester, First; Quinazolines

2006
Practical approach to treating essential thrombocythaemia: case studies.
    European journal of haematology. Supplementum, 2007, Issue:68

    Topics: Adult; Aspirin; Disease Management; Female; Humans; Hydroxyurea; Interferon-alpha; Leg Ulcer; Male; Middle Aged; Pipobroman; Platelet Count; Pregnancy; Pregnancy Complications, Hematologic; Quinazolines; Thrombocythemia, Essential; Warfarin

2007
Paucity of pericytes in germinal matrix vasculature of premature infants.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Oct-31, Volume: 27, Issue:44

    Topics: Animals; Antigens; Antigens, CD34; Autopsy; Blood-Brain Barrier; Cadherins; Cerebral Cortex; Female; Fetus; Gestational Age; Humans; Infant, Newborn; Lysophospholipids; Pericytes; Piperidines; Pregnancy; Premature Birth; Proteoglycans; Quinazolines; Rabbits; Sphingosine; Time Factors; Transforming Growth Factor beta1

2007
Erlotinib administration for advanced non-small cell lung cancer during the first 2 months of unrecognized pregnancy.
    Lung cancer (Amsterdam, Netherlands), 2008, Volume: 60, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Cesarean Section; Disease Progression; Drug Administration Schedule; Erlotinib Hydrochloride; Female; Humans; Infant, Newborn; Lung Neoplasms; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Trimester, First; Quinazolines; Withholding Treatment

2008
Treatment of breast cancer with trastuzumab during pregnancy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Mar-20, Volume: 26, Issue:9

    Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Deoxycytidine; Female; Fluorouracil; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Lapatinib; Lung Neoplasms; Mastectomy, Modified Radical; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Outcome; Quinazolines; Trastuzumab

2008
[3H]prazosin binding to central nervous system regions of male and female rats.
    Neuroscience letters, 1984, Aug-24, Volume: 49, Issue:1-2

    Topics: Animals; Central Nervous System; Estrus; Female; Male; Prazosin; Pregnancy; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sex Factors

1984
Combined alpha- and beta-adrenoceptor antagonism with prazosin and oxprenolol in control of severe hypertension in pregnancy.
    The New Zealand medical journal, 1981, Sep-09, Volume: 94, Issue:691

    Topics: Acute Disease; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adult; Drug Therapy, Combination; Edema; Female; Humans; Hypertension; Infant, Newborn; Infant, Newborn, Diseases; Oxprenolol; Prazosin; Pregnancy; Pregnancy Complications, Cardiovascular; Proteinuria; Quinazolines

1981
Clinical pharmacological studies with prazosin during pregnancy complicated by hypertension.
    British journal of clinical pharmacology, 1983, Volume: 16, Issue:5

    Topics: Adolescent; Adult; Female; Humans; Hypertension; Prazosin; Pregnancy; Pregnancy Complications, Cardiovascular; Quinazolines

1983
Effect of prazosin on the function of the teat sphincter in lactating cows.
    The Journal of dairy research, 1984, Volume: 51, Issue:2

    Topics: Animals; Cattle; Female; Injections, Intra-Arterial; Injections, Intravenous; Lactation; Mammary Glands, Animal; Milk Ejection; Muscle Relaxation; Muscle, Smooth; Oxytocin; Plethysmography; Prazosin; Pregnancy; Quinazolines

1984
Alkaline phosphatase inhibition by a series of pyrido[2,1-b]quinazolines: A possible relationship with cromolyn-like antiallergy activity.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:6

    Topics: Alkaline Phosphatase; Animals; Chemical Phenomena; Chemistry; Cromolyn Sodium; Female; Humans; Hypersensitivity; In Vitro Techniques; Leukocytes; Passive Cutaneous Anaphylaxis; Placenta; Pregnancy; Quinazolines; Rats

1982
Prazosin and oxprenolol therapy in pregnancy hypertension.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1983, Aug-13, Volume: 64, Issue:7

    Topics: Blood Pressure; Drug Therapy, Combination; Female; Humans; Hypertension; Oxprenolol; Prazosin; Pregnancy; Pregnancy Complications, Cardiovascular; Prospective Studies; Quinazolines

1983
Prazosin hydrochloride.
    The Australian nurses' journal. Royal Australian Nursing Federation, 1980, Volume: 10, Issue:2

    Topics: Adult; Animals; Child; Dogs; Female; Humans; Hypertension; Male; Prazosin; Pregnancy; Quinazolines

1980
Effects of 5,8-dideazaisofolic acid (IAHQ) on human tumor cells in culture and on normal and tumor-bearing hamsters.
    Chemotherapy, 1982, Volume: 28, Issue:4

    Topics: Animals; Cell Division; Cell Line; Cricetinae; Cytotoxicity, Immunologic; Drug Resistance; Female; Folic Acid Antagonists; Humans; Lymphocyte Activation; Methotrexate; Neoplasms; Osteosarcoma; Pregnancy; Quinazolines; Sarcoma, Experimental

1982
Toxicological evaluation of fluproquazone.
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:5a

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carcinogens; Female; Fertility; Lethal Dose 50; Macaca fascicularis; Male; Mice; Mutagens; Pregnancy; Quinazolines; Quinazolinones; Rabbits; Rats; Teratogens; Time Factors

1981
[General pharmacology of 6-amino-2-fluoromethyl-3-(o-tolyl)-4(3H)-quinazolinone (afloqualone), a new centrally acting muscle relaxant. II. Effects on the peripheral system (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1981, Volume: 78, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Autonomic Nervous System; Cardiovascular System; Cats; Digestive System; Dogs; Female; Guinea Pigs; In Vitro Techniques; Male; Mice; Muscle Relaxants, Central; Pregnancy; Quinazolines; Rabbits; Rats; Rats, Inbred Strains; Respiration; Urogenital System; Uterine Contraction

1981
The management of hypertension in pregnancy.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1981, Mar-07, Volume: 59, Issue:10

    Topics: Adult; Dihydralazine; Drug Therapy, Combination; Female; Humans; Hypertension; Oxprenolol; Prazosin; Pregnancy; Pregnancy Complications, Cardiovascular; Quinazolines

1981
Differential affinity of dihydroimidazoquinoxalines and diimidazoquinazolines to the alpha 1 beta 2 gamma 2 and alpha 6 beta 2 gamma 2 subtypes of cloned GABAA receptors.
    British journal of pharmacology, 1993, Volume: 110, Issue:2

    Topics: Cells, Cultured; Electrophysiology; Female; Humans; Imidazoles; Kidney; Ligands; Molecular Conformation; Pregnancy; Quinazolines; Quinoxalines; Receptors, GABA-A; Structure-Activity Relationship

1993
Studies on disease-modifying antirheumatic drugs: synthesis of novel quinoline and quinazoline derivatives and their anti-inflammatory effect.
    Journal of medicinal chemistry, 1996, Dec-20, Volume: 39, Issue:26

    Topics: Animals; Antirheumatic Agents; Arthritis, Experimental; Bone Resorption; Dinoprostone; Disease Models, Animal; Female; Magnetic Resonance Spectroscopy; Male; Pregnancy; Quinazolines; Quinolines; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Structure-Activity Relationship

1996
The cGMP-specific phosphodiesterase inhibitor E4021 dilates the pulmonary circulation.
    American journal of respiratory and critical care medicine, 1999, Volume: 160, Issue:3

    Topics: Analysis of Variance; Animals; Animals, Newborn; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fetus; Humans; Infant, Newborn; Infusions, Intravenous; Nitric Oxide; Persistent Fetal Circulation Syndrome; Phosphodiesterase Inhibitors; Piperidines; Pregnancy; Pulmonary Artery; Pulmonary Circulation; Quinazolines; Sheep; Statistics, Nonparametric; Vasodilation

1999
Activation of BAD by therapeutic inhibition of epidermal growth factor receptor and transactivation by insulin-like growth factor receptor.
    The Journal of biological chemistry, 2002, Aug-02, Volume: 277, Issue:31

    Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-Associated Death Protein; Carrier Proteins; Cell Death; Cell Line; Cell Survival; Cells, Cultured; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; Female; Gefitinib; Insulin-Like Growth Factor I; Mammary Glands, Animal; MAP Kinase Signaling System; Mice; Mice, Inbred ICR; Mice, Knockout; Phosphatidylinositol 3-Kinases; Pregnancy; Quinazolines; Receptors, Somatomedin; Signal Transduction; Transcriptional Activation

2002
The role of prazosin in the management of hypertension.
    The Medical journal of Australia, 1977, Aug-27, Volume: 2, Issue:2 Suppl

    Topics: Adolescent; Adrenergic beta-Antagonists; Anesthesia, General; Child; Coronary Disease; Diuretics; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Prazosin; Pregnancy; Pregnancy Complications, Cardiovascular; Quinazolines

1977
Studies on 3-aminobenzo-6, 7 quinazolone-4-one (centazolone, compound 65/469), a new tranquillosedative compound: Part IX influence of centazolone on prenatal development in mice & rabbits.
    Indian journal of experimental biology, 1978, Volume: 16, Issue:2

    Topics: Animals; Female; Fetus; Hypnotics and Sedatives; Mice; Pregnancy; Quinazolines; Rabbits; Tranquilizing Agents

1978
Vasicine, alkaloid of Adhatoda vasica, a promising uterotonic abortifacient.
    Indian journal of experimental biology, 1978, Volume: 16, Issue:10

    Topics: Abortifacient Agents; Alkaloids; Animals; Female; Guinea Pigs; Plants, Medicinal; Pregnancy; Quinazolines; Rats

1978
Prazosin alone and combined with a thiazide diuretic in the treatment of hypertension.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1977, Apr-02, Volume: 51, Issue:14

    Topics: Adult; Aged; Cyclopenthiazide; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Prazosin; Pregnancy; Quinazolines; Sodium Chloride Symporter Inhibitors

1977
Successful treatment of oligospermic and azoospermic men with alpha 1-blocker and beta-stimulator: new treatment for idiopathic male infertility.
    Fertility and sterility, 1986, Volume: 46, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Ethanolamines; Female; Humans; Infertility, Male; Male; Oligospermia; Pregnancy; Procaterol; Quinazolines; Sperm Count; Sperm Motility; Time Factors

1986
Teratogenicity of the antiallergic Sm 857 SE in rats versus rabbits.
    Teratology, 1988, Volume: 38, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Female; Fetus; Histamine H1 Antagonists; Pregnancy; Quinazolines; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Teratogens

1988
Chemical structure and teratogenic properties. II. Synthesis and teratogenic activity in rabbits of some derivatives of phthalmide, isoindoline-1-one, 1,2-benzisothiazoline-3-one-1,1-dioxide and 4(3H)-quinazolinone.
    Acta pharmaceutica Suecica, 1972, Volume: 9, Issue:5

    Topics: Abnormalities, Drug-Induced; Acetamides; Animals; Female; Imides; Indoles; Pregnancy; Quinazolines; Rabbits; Succinimides; Thiazoles

1972
Pharmacology of some new 4-(3H) quinazolinones. II. Effect on reproduction, blood pressure and respiration.
    The Indian journal of medical research, 1972, Volume: 60, Issue:2

    Topics: Animals; Blood Pressure; Female; Fertility; Pregnancy; Quinazolines; Rats; Respiration; Structure-Activity Relationship

1972
Maternal and fetal toxicity of moquizone.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:10

    Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Cholagogues and Choleretics; Delivery, Obstetric; Drug Tolerance; Female; Fetus; Maternal-Fetal Exchange; Methods; Mice; Morpholines; Pregnancy; Pregnancy, Animal; Quinazolines; Rabbits; Rats; Receptors, Drug

1970