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quinazolines and Precursor Cell Lymphoblastic Leukemia-Lymphoma

quinazolines has been researched along with Precursor Cell Lymphoblastic Leukemia-Lymphoma in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (53.33)18.2507
2000's1 (6.67)29.6817
2010's5 (33.33)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Goto, H; Goto, S; Hamanoue, S; Inukai, T; Ito, M; Iwasaki, F; Keino, D; Kumamoto, T; Miyagawa, N; Nagai, J; Sakurai, Y; Shiomi, M; Yokosuka, T; Yoshino, Y1
Allen, M; Caron, HN; Clifford, SC; Den Boer, ML; Exalto, C; Hartsink-Segers, SA; Horstmann, M; Pieters, R; Williamson, D1
Beausoleil, S; Druker, BJ; Gu, TL; Gygi, SP; Heinrich, MC; Kornhauser, J; Loriaux, M; MacNeill, J; Nardone, J; Polakiewicz, RD; Ren, J; Rush, J; Tucker, M; Villén, J; Wang, Y1
Abdel-Halim, H; Failes, TW; Hibbs, DE; Kavallaris, M; Liu, M; Mitic, G; Po'uha, ST1
Calvert, VS; Caron, HN; de Haas, V; Den Boer, ML; Evans, WE; Exalto, C; Hansen, BR; Hartsink-Segers, SA; Hedtjärn, M; Koch, T; Luijendijk, MW; Petricoin, EF; Pieters, R; Reinhardt, D; Zwaan, CM1
Mimoso Pinhanços, S; Pieters, R; Schneider, P; Spijkers-Hagelstein, JA; Stam, RW1
Haile, WH; Heitzman, KJ; McCloskey, DE; McGuire, JJ; Piper, JR; Russell, CA1
Gibson, W; Jackman, AL; Kimbell, R; Kobayashi, H; Miyachi, H; Takemura, Y1
Bertino, JR; Ercikan, E; Gorlick, R; Longo, GS; Tong, WP1
Kobayashi, H; Ohnuma, T; Takemura, Y1
Chelstrom, LM; Crankshaw, DL; Ek, O; Myers, DE; Reaman, GH; Uckun, FM1
Ablett, S; Boddy, AV; Brampton, M; Clendeninn, N; Estlin, EJ; Hobson, R; Johnston, A; Kohler, J; Lashford, L; Lewis, IJ; McDowell, H; Morland, B; Newell, DR; Pearson, AD; Pinkerton, CR; Pitsiladis, M; Price, L; Taylor, GA1
Ohnuma, T; Takemura, Y1
Miyachi, H; Ohnuma, T; Sekiguchi, S; Takemura, Y1
Alvarado, C; Dubowy, R; Kamen, B; Pappo, A; Rao, S; Ravindranath, Y; Vega, R; Vietti, T; Whitehead, VM1

Trials

2 trial(s) available for quinazolines and Precursor Cell Lymphoblastic Leukemia-Lymphoma

ArticleYear
A phase I study of nolatrexed dihydrochloride in children with advanced cancer. A United Kingdom Children's Cancer Study Group Investigation.
    British journal of cancer, 2001, Jan-05, Volume: 84, Issue:1

    Topics: Acute Disease; Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Enzyme Inhibitors; Female; Humans; Infant; Leukemia, Myeloid; Male; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Quinazolines

2001
Phase II trial of trimetrexate in the treatment of recurrent childhood acute lymphoblastic leukemia: a Pediatric Oncology Group study.
    Journal of the National Cancer Institute, 1990, Oct-17, Volume: 82, Issue:20

    Topics: Adolescent; Child; Child, Preschool; Drug Administration Schedule; Female; Humans; Infant; Infusions, Intravenous; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Quinazolines; Recurrence; Remission Induction; Trimetrexate

1990

Other Studies

13 other study(ies) available for quinazolines and Precursor Cell Lymphoblastic Leukemia-Lymphoma

ArticleYear
Aurora B kinase as a therapeutic target in acute lymphoblastic leukemia.
    Cancer chemotherapy and pharmacology, 2020, Volume: 85, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Aurora Kinase A; Cell Cycle; Cell Proliferation; Docetaxel; Drug Therapy, Combination; Furans; High-Throughput Screening Assays; Humans; Ketones; Phosphorylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Quinazolines; Tumor Cells, Cultured; Vincristine

2020
Inhibiting Polo-like kinase 1 causes growth reduction and apoptosis in pediatric acute lymphoblastic leukemia cells.
    Haematologica, 2013, Volume: 98, Issue:10

    Topics: Apoptosis; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Child; Cohort Studies; Gene Knockdown Techniques; HEK293 Cells; Humans; Polo-Like Kinase 1; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pyrazoles; Quinazolines

2013
Survey of activated FLT3 signaling in leukemia.
    PloS one, 2011, Apr-28, Volume: 6, Issue:4

    Topics: Bone Marrow Cells; Cell Line, Tumor; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Mutation; Phosphoamino Acids; Phosphorylation; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Quinazolines; Signal Transduction

2011
Evolution of resistance to Aurora kinase B inhibitors in leukaemia cells.
    PloS one, 2012, Volume: 7, Issue:2

    Topics: Apoptosis; Aurora Kinase A; Aurora Kinase B; Aurora Kinases; Benzamides; Binding Sites; Catalytic Domain; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Leukemia, T-Cell; Mutation, Missense; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Quinazolines

2012
Aurora kinases in childhood acute leukemia: the promise of aurora B as therapeutic target.
    Leukemia, 2013, Volume: 27, Issue:3

    Topics: Adult; Apoptosis; Aurora Kinase A; Aurora Kinase B; Aurora Kinases; Biomarkers, Tumor; Blotting, Western; Bone Marrow; Case-Control Studies; Cell Proliferation; Child; Gene Expression Profiling; Humans; Leukemia, Myeloid, Acute; Oligonucleotide Array Sequence Analysis; Oligonucleotides; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Serine-Threonine Kinases; Quinazolines; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured

2013
Src kinase-induced phosphorylation of annexin A2 mediates glucocorticoid resistance in MLL-rearranged infant acute lymphoblastic leukemia.
    Leukemia, 2013, Volume: 27, Issue:5

    Topics: Annexin A2; Benzodioxoles; Cell Proliferation; Drug Resistance, Neoplasm; Gene Rearrangement; Histone-Lysine N-Methyltransferase; Humans; Myeloid-Lymphoid Leukemia Protein; Phosphorylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Quinazolines; RNA, Messenger; S100 Proteins; src-Family Kinases

2013
Cross-resistance studies of folylpolyglutamate synthetase-deficient, methotrexate-resistant CCRF-CEM human leukemia sublines.
    Leukemia, 1993, Volume: 7, Issue:12

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Cell Division; Drug Resistance; Folic Acid Antagonists; Humans; Leucovorin; Methotrexate; Peptide Synthases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrimidines; Quinazolines; Tetrahydrofolates; Thiophenes; Tumor Cells, Cultured

1993
Cellular pharmacokinetics of ZD1694 in cultured human leukaemia cells sensitive, or made resistant, to this drug.
    Journal of cancer research and clinical oncology, 1996, Volume: 122, Issue:2

    Topics: Antimetabolites, Antineoplastic; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Folic Acid; Humans; Intracellular Fluid; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Polyglutamic Acid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Quinazolines; Tetrahydrofolate Dehydrogenase; Thiophenes; Thymidylate Synthase; Tritium; Tumor Cells, Cultured

1996
Disparate affinities of antifolates for folylpolyglutamate synthetase from human leukemia cells.
    Blood, 1997, Aug-01, Volume: 90, Issue:3

    Topics: Acute Disease; Antimetabolites, Antineoplastic; Drug Resistance, Neoplasm; Enzyme Inhibitors; Folic Acid Antagonists; HL-60 Cells; Humans; Indoles; Isoindoles; Kinetics; Leukemia, Myeloid; Methotrexate; Neoplasm Proteins; Organ Specificity; Peptide Synthases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Quinazolines; Thiophenes; Thymidylate Synthase; Tumor Cells, Cultured

1997
Variable expression of RFC1 in human leukemia cell lines resistant to antifolates.
    Cancer letters, 1998, Feb-27, Volume: 124, Issue:2

    Topics: Antimetabolites, Antineoplastic; Biological Transport; Carrier Proteins; Drug Resistance, Neoplasm; Folic Acid; Folic Acid Antagonists; Humans; Leucovorin; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Membrane Proteins; Membrane Transport Proteins; Methotrexate; Phenotype; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Quinazolines; Tetrahydrofolate Dehydrogenase; Thiophenes; Tumor Cells, Cultured

1998
Combined therapeutic efficacy of the thymidylate synthase inhibitor ZD1694 (Tomudex) and the immunotoxin B43(anti-CD19)-PAP in a SCID mouse model of human B-lineage acute lymphoblastic leukemia.
    Leukemia & lymphoma, 1998, Volume: 28, Issue:5-6

    Topics: Animals; Antigens, CD19; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; B-Lymphocytes; Cell Lineage; Combined Modality Therapy; Disease Models, Animal; Enzyme Inhibitors; Humans; Immunotoxins; Mice; Mice, SCID; N-Glycosyl Hydrolases; Plant Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Quinazolines; Ribosome Inactivating Proteins, Type 1; Survival Analysis; Thiophenes; Thymidylate Synthase

1998
N10-propargyl-5,8-dideazafolic acid (CB3717): inhibitory effects on human leukemia cell lines resistant to methotrexate or trimetrexate.
    The Mount Sinai journal of medicine, New York, 1992, Volume: 59, Issue:5

    Topics: Antineoplastic Agents; Cell Division; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Folic Acid; Folic Acid Antagonists; Humans; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Quinazolines; Thymidylate Synthase; Trimetrexate; Tumor Cells, Cultured

1992
A human leukemia cell line made resistant to two folate analogues, trimetrexate and N10-propargyl-5,8-dideazafolic acid (CB3717).
    Journal of cancer research and clinical oncology, 1991, Volume: 117, Issue:6

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Division; Cell Line; Cisplatin; Cross Reactions; Dactinomycin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Etoposide; Fluorouracil; Folic Acid; Humans; Leucovorin; Membrane Glycoproteins; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Quinazolines; RNA, Messenger; Thymidylate Synthase; Trimetrexate; Vincristine

1991