Page last updated: 2024-08-21

quinazolines and Polycythemia Vera

quinazolines has been researched along with Polycythemia Vera in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.78)18.7374
1990's3 (8.33)18.2507
2000's18 (50.00)29.6817
2010's12 (33.33)24.3611
2020's2 (5.56)2.80

Authors

AuthorsStudies
Fleischman, A; Gotlib, J; Heaney, M; Hoffman, R; Kremyanskaya, M; Kuykendall, A; Mascarenhas, J; Mesa, R; O'Connell, C; Podoltsev, N; Rippel, N; Shammo, JM; Tremblay, D; Yacoub, A; Zubizarreta, N1
Besses, C; Blau, IW; Dong, T; Durrant, S; Francillard, N; Griesshammer, M; Harrison, CN; Hino, M; Kiladjian, JJ; Kirito, K; Masszi, T; Mesa, R; Miller, CB; Moiraghi, B; Pane, F; Passamonti, F; Rosti, V; Rumi, E; Vannucchi, AM; Verstovsek, S; Wroclawska, M; Zachee, P1
Begna, KH; Christopher Hook, C; Elliott, MA; Gangat, N; Hanson, CA; Ketterling, RP; Pardanani, A; Patnaik, MM; Szuber, N; Tefferi, A; Vallapureddy, RR; Wolanskyj, AP1
Ahn, IE; Natelson, E; Rice, L1
Newberry, KJ; Sever, M; Verstovsek, S1
De Raeve, H; Gadisseur, A; Michiels, JJ; Pich, A1
Miyamoto, T; Yoshimoto, G1
Al-Kali, A; Cherry, M; Ghabache, B; Khawandanah, M; Ozer, H; Selby, G; Srour, S; Zhao, ZJ1
Bang, SM; Kim, JW; Kim, SH; Kim, YJ; Lee, JO; Lee, JS; Lee, KW; Lim, Y1
Hoffman, R; Kremyanskaya, M; Mascarenhas, J1
Aksu, S; Büyükaşık, Y; Eliaçık, E; Göker, H; Haznedaroğlu, İC; Işık, A; Özcebe, OI; Sayınalp, N; Üner, A1
Besses, C; Burgaleta, C; Hernández-Boluda, JC; Hernández-Rivas, JM; Jiménez Velasco, A; Martínez Lopez, J; Pérez Encinas, M; Raya, JM; Vicente, V1
Barbui, T; Finazzi, G1
Anastasiadis, A; Bourikas, G; Christoforidou, A; Goutzouvelidis, A; Kaloutsi, V; Kotsianidis, I; Margaritis, D; Pantelidou, D; Spanoudakis, E; Tsatalas, C1
Dai, Y; Hoffman, R; Ishii, T; Mascarenhas, J; Najfeld, V; Sozer, S; Wang, J; Wisch, N; Xu, M; Zhang, W; Zhao, ZJ1
Beer, PA; Green, AR1
Buliková, A; Doubek, M; Dulícek, P; Hlusí, A; Kissová, J; Korístek, Z; Ovesná, P; Pavlík, T; Penka, M; Pospísilová, D; Schwarz, J1
Li, Y; Ren, YY; Zhang, LY1
Gilbert, HS2
Campbell, PJ; Curtin, N; Green, AR; Vassiliou, GS1
Barbui, T1
Jurgens, DJ; Moreno-Aspitia, A; Tefferi, A1
Fu, X; Ho, WT; Ishii, T; Li, Q; Li, Z; Xing, S; Xu, M; Zhao, ZJ1
Birgegård, G; Engström-Laurent, A; Hultdin, M; Lundström, B; Samuelsson, J; Sundström, G; Wahlin, A1
Brychtová, Y; Bubeník, B; Cerná, O; Doubek, M; Dulícek, P; Dusek, L; Hadacová, I; Hlusí, A; Hochová, I; Kissová, J; Lhotanová, T; Micaníková, M; Pavlík, T; Penka, M; Pospísilová, D; Pytlík, R; Schützová, M; Schwarz, J; Seghetová, J; Szotkowski, T; Voglová, J; Volková, Z; Vozobulová, V; Vránová, M; Zapletal, O1
Bareford, D; Buck, G; Campbell, PJ; East, CL; Erber, WN; Green, AR; Harrison, CN; Paul, B; Wheatley, K; Wilkins, BS1
Elliott, MA; Silverstein, MN; Solberg, LA; Tefferi, A1
Sréter, L1
Silverstein, MN; Tefferi, A1
Barbui, T; Finazzi, G; Fuchtman, SM; Kutti, J; Michiels, JJ; Rain, JD; Silver, RT; Tefferi, A; Thiele, J1
James, CW1
Hehlmann, R; Lengfelder, E1
Bennett, M; Grunwald, AJ1
Solberg, LA1
Fleming, JS; Knight, RC; Petitt, RM; Schacter, LP; Silverstein, MN; Solberg, LA1

Reviews

15 review(s) available for quinazolines and Polycythemia Vera

ArticleYear
Therapeutic options for patients with polycythemia vera and essential thrombocythemia refractory/resistant to hydroxyurea.
    Leukemia & lymphoma, 2014, Volume: 55, Issue:12

    Topics: Antineoplastic Agents; Busulfan; Disease Management; Drug Resistance; Histone Deacetylase Inhibitors; Humans; Hydroxyurea; Interferon-alpha; Janus Kinase 2; Pipobroman; Platelet Aggregation Inhibitors; Polycythemia Vera; Protein Kinase Inhibitors; Quinazolines; Thrombocythemia, Essential; Treatment Outcome

2014
[Treatment strategy for myeloproliferative neoplasms].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:10

    Topics: Adrenal Cortex Hormones; Aspirin; Calreticulin; Carbamates; Clinical Trials as Topic; Drug Therapy, Combination; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Immunosuppressive Agents; Janus Kinase 2; Molecular Targeted Therapy; Mutation; Nitriles; Platelet Aggregation Inhibitors; Polycythemia Vera; Primary Myelofibrosis; Prognosis; Pyrazoles; Pyrimidines; Quinazolines; Receptors, Thrombopoietin; Thalidomide; Thrombocythemia, Essential

2014
Anagrelide hydrochloride and ruxolitinib for treatment of polycythemia vera.
    Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:8

    Topics: Aspirin; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Hydroxyurea; Interferon-alpha; Nitriles; Platelet Aggregation Inhibitors; Polycythemia Vera; Polyethylene Glycols; Pyrazoles; Pyrimidines; Quinazolines

2015
Pharmacobiological Approach for the Clinical Development of Ruxolitinib in Myeloproliferative Neoplasms.
    Turkish journal of haematology : official journal of Turkish Society of Haematology, 2015, Volume: 32, Issue:2

    Topics: Bone Marrow; Combined Modality Therapy; Disease Progression; Female; Fibrosis; Humans; Hydroxyurea; Janus Kinase 2; Leukapheresis; Middle Aged; Myeloproliferative Disorders; Nitriles; Phlebotomy; Point Mutation; Polycythemia Vera; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Quinazolines; Splenectomy; Splenomegaly

2015
Evidence and expertise in the management of polycythemia vera and essential thrombocythemia.
    Leukemia, 2008, Volume: 22, Issue:8

    Topics: Aspirin; Humans; Hydroxyurea; Interferon-alpha; Janus Kinase 2; Mutation; Phlebotomy; Polycythemia Vera; Quinazolines; Risk Factors; Survival Analysis; Thrombocythemia, Essential

2008
Pathogenesis and management of essential thrombocythemia.
    Hematology. American Society of Hematology. Education Program, 2009

    Topics: Acute Disease; Aged; Aspirin; Clone Cells; Disease Management; Disease Progression; Humans; Hydroxyurea; Interferon-alpha; Janus Kinase 2; Leukemia, Myeloid; Middle Aged; Models, Biological; Mutation, Missense; Polycythemia Vera; Primary Myelofibrosis; Prognosis; Protein Kinase Inhibitors; Quinazolines; Thrombocythemia, Essential; Thrombophilia

2009
Modern treatment strategies in polycythemia vera.
    Seminars in hematology, 2003, Volume: 40, Issue:1 Suppl 1

    Topics: Age Factors; Antineoplastic Agents; Drug Therapy, Combination; Humans; Hydroxyurea; Interferon-alpha; Phlebotomy; Platelet Aggregation Inhibitors; Polycythemia Vera; Quinazolines; Risk Factors

2003
Management of the myeloproliferative disorders : distinguishing data from dogma.
    The hematology journal : the official journal of the European Haematology Association, 2004, Volume: 5 Suppl 3

    Topics: Abnormalities, Drug-Induced; Adult; Aged; Anticoagulants; Contraindications; Female; Humans; Hydroxyurea; Interferon-alpha; Male; Middle Aged; Myeloproliferative Disorders; Phlebotomy; Polycythemia Vera; Pregnancy; Pregnancy Complications, Hematologic; Prognosis; Quinazolines; Randomized Controlled Trials as Topic; Thrombocythemia, Essential; Thrombophilia

2004
The leukemia controversy in myeloproliferative disorders: is it a natural progression of disease, a secondary sequela of therapy, or a combination of both?
    Seminars in hematology, 2004, Volume: 41, Issue:2 Suppl 3

    Topics: Age Factors; Aged; Antineoplastic Agents, Alkylating; Antiviral Agents; Disease Progression; Female; Humans; Hydroxyurea; Interferon-alpha; Leukemia; Male; Middle Aged; Platelet Aggregation Inhibitors; Polycythemia Vera; Quinazolines; Risk Factors; Thrombocythemia, Essential; Thrombosis

2004
New drugs in essential thrombocythemia and polycythemia vera.
    Blood reviews, 1997, Volume: 11, Issue:1

    Topics: Antineoplastic Agents; Fibrinolytic Agents; Humans; Interferon alpha-2; Interferon-alpha; Polycythemia Vera; Quinazolines; Recombinant Proteins; Thrombocytosis

1997
Treatment of polycythaemia vera and essential thrombocythaemia.
    Bailliere's clinical haematology, 1998, Volume: 11, Issue:4

    Topics: Adult; Aged; Aspirin; Chlorambucil; Disease Progression; Female; Hemorrhage; Humans; Hydroxyurea; Interferon-alpha; Leukemia, Myeloid; Leukemia, Radiation-Induced; Male; Middle Aged; Phlebotomy; Phosphorus Radioisotopes; Pipobroman; Polycythemia Vera; Primary Myelofibrosis; Prospective Studies; Quinazolines; Thrombocythemia, Essential; Thrombosis

1998
Diagnosis and treatment of polycythemia vera and possible future study designs of the PVSG.
    Leukemia & lymphoma, 2000, Volume: 36, Issue:3-4

    Topics: Blood Platelets; Forecasting; Humans; Hydroxyurea; Interferon-alpha; Megakaryocytes; Platelet Aggregation Inhibitors; Polycythemia Vera; Prospective Studies; Quinazolines; Randomized Controlled Trials as Topic

2000
[Polycythemia vera: current status of therapy].
    Deutsche medizinische Wochenschrift (1946), 2000, Oct-13, Volume: 125, Issue:41

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Bloodletting; Clinical Trials as Topic; Fibrinolytic Agents; Humans; Hydroxyurea; Interferon-alpha; Leukemia; Middle Aged; Phlebotomy; Pipobroman; Platelet Aggregation Inhibitors; Polycythemia Vera; Prognosis; Prospective Studies; Quinazolines; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Thromboembolism

2000
Diagnosis and treatment of thrombocythemia in myeloproliferative disorders.
    Oncology (Williston Park, N.Y.), 2001, Volume: 15, Issue:8

    Topics: Enzyme Inhibitors; Humans; Hydroxyurea; Immunologic Factors; Interferon-alpha; Polycythemia Vera; Quinazolines; Thrombocytosis

2001
Therapeutic options for essential thrombocythemia and polycythemia vera.
    Seminars in oncology, 2002, Volume: 29, Issue:3 Suppl 10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Busulfan; Fibrinolytic Agents; Humans; Hydroxyurea; Immunologic Factors; Immunosuppressive Agents; Interferon-alpha; Nucleic Acid Synthesis Inhibitors; Phosphorus Radioisotopes; Polycythemia Vera; Quinazolines; Risk Assessment; Thrombocytosis

2002

Trials

4 trial(s) available for quinazolines and Polycythemia Vera

ArticleYear
Long-term efficacy and safety of ruxolitinib versus best available therapy in polycythaemia vera (RESPONSE): 5-year follow up of a phase 3 study.
    The Lancet. Haematology, 2020, Volume: 7, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Drug Therapy, Combination; Fibrinolytic Agents; Follow-Up Studies; Humans; Hydroxyurea; Interferon alpha-2; Interferon-alpha; Nitriles; Pipobroman; Polycythemia Vera; Polyethylene Glycols; Prognosis; Pyrazoles; Pyrimidines; Quinazolines; Recombinant Proteins; Survival Rate; Time Factors

2020
Erlotinib is not effective in patients with JAK2V617F-positive polycythemia vera.
    Annals of hematology, 2015, Volume: 94, Issue:4

    Topics: Adult; Aged; Amino Acid Substitution; Antineoplastic Agents; Drug-Related Side Effects and Adverse Reactions; Erlotinib Hydrochloride; Female; Humans; Janus Kinase 2; Male; Middle Aged; Phenylalanine; Polycythemia Vera; Quinazolines; Treatment Outcome; Valine

2015
Progression of bone marrow fibrosis in patients with essential thrombocythemia and polycythemia vera during anagrelide treatment.
    Medical oncology (Northwood, London, England), 2007, Volume: 24, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Disease Progression; Female; Fibrinolytic Agents; Humans; Hyaluronic Acid; Male; Middle Aged; Polycythemia Vera; Primary Myelofibrosis; Prognosis; Prospective Studies; Quinazolines; Reticulin; Thrombocythemia, Essential; Thrombocytosis

2007
Bone marrow pathology in essential thrombocythemia: interobserver reliability and utility for identifying disease subtypes.
    Blood, 2008, Jan-01, Volume: 111, Issue:1

    Topics: Adult; Antineoplastic Agents; Aspirin; Biopsy; Blood Cell Count; Drug Therapy, Combination; Hematology; Humans; Hydroxyurea; Megakaryocytes; Observer Variation; Pathology, Clinical; Platelet Aggregation Inhibitors; Polycythemia Vera; Primary Myelofibrosis; Prospective Studies; Quinazolines; Thrombocytosis

2008

Other Studies

17 other study(ies) available for quinazolines and Polycythemia Vera

ArticleYear
Anagrelide for platelet-directed cytoreduction in polycythemia vera: Insights into utility and safety outcomes from a large multi-center database.
    Leukemia research, 2022, Volume: 119

    Topics: Cytoreduction Surgical Procedures; Humans; Polycythemia Vera; Quinazolines; Thrombocythemia, Essential; Thrombocytosis; Thrombosis

2022
Decreased survival and increased rate of fibrotic progression in essential thrombocythemia chronicled after the FDA approval date of anagrelide.
    American journal of hematology, 2019, Volume: 94, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bone Marrow; Disease Progression; Disease-Free Survival; Drug Approval; Female; Fibrosis; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Mortality; Platelet Aggregation Inhibitors; Polycythemia Vera; Primary Myelofibrosis; Prognosis; Proportional Hazards Models; Quinazolines; Retrospective Studies; Severity of Illness Index; Thrombocythemia, Essential; Thrombosis; Treatment Outcome; Young Adult

2019
Successful long-term treatment of Philadelphia chromosome-negative myeloproliferative neoplasms with combination of hydroxyurea and anagrelide.
    Clinical lymphoma, myeloma & leukemia, 2013, Volume: 13 Suppl 2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Hydroxyurea; Male; Middle Aged; Myeloproliferative Disorders; Philadelphia Chromosome; Polycythemia Vera; Quinazolines; Retrospective Studies; Thrombocythemia, Essential; Thrombosis

2013
Essential differences in clinical and bone marrow features in BCR/ABL-positive thrombocythemia compared to thrombocythemia in the BCR/ABL-negative myeloproliferative neoplasms essential thrombocythemia and polycythemia vera.
    Acta haematologica, 2015, Volume: 133, Issue:1

    Topics: Aged; Alleles; Benzamides; Biopsy; Bone Marrow; Diagnosis, Differential; Drug Therapy, Combination; Female; Fusion Proteins, bcr-abl; Humans; Hydroxyurea; Imatinib Mesylate; Janus Kinase 2; Male; Middle Aged; Mutation; Myeloproliferative Disorders; Piperazines; Platelet Count; Polycythemia Vera; Pyrimidines; Quinazolines; Thrombocythemia, Essential; Treatment Outcome

2015
Prediction of thrombotic and hemorrhagic events during polycythemia vera or essential thrombocythemia based on leukocyte burden.
    Thrombosis research, 2015, Volume: 135, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Area Under Curve; Blood Cell Count; Comorbidity; Databases, Factual; Female; Follow-Up Studies; Hemorrhage; Hemorrhagic Disorders; Humans; Hydroxyurea; Leukocyte Count; Male; Middle Aged; Phlebotomy; Platelet Aggregation Inhibitors; Polycythemia Vera; Prognosis; Quinazolines; Retrospective Studies; Risk Factors; Thrombocythemia, Essential; Thrombophilia; Thrombosis; Young Adult

2015
Current opinion and consensus statement regarding the diagnosis, prognosis, and treatment of patients with essential thrombocythemia: a survey of the Spanish Group of Ph-negative Myeloproliferative Neoplasms (GEMFIN) using the Delphi method.
    Annals of hematology, 2016, Volume: 95, Issue:5

    Topics: Bone Marrow Examination; Delphi Technique; Diagnosis, Differential; Disease Management; DNA Mutational Analysis; Humans; Hydroxyurea; Janus Kinase 2; Mutation, Missense; Platelet Count; Polycythemia Vera; Prognosis; Quinazolines; Receptors, Thrombopoietin; Risk Assessment; Surveys and Questionnaires; Thrombocythemia, Essential; Thrombophilia

2016
Hydroxyurea and anagrelide combination therapy in patients with chronic myeloproliferative diseases resistant or intolerant to monotherapy.
    Acta haematologica, 2008, Volume: 120, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Drug Resistance; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Male; Middle Aged; Polycythemia Vera; Quinazolines; Thrombocythemia, Essential

2008
Involvement of mast cells by the malignant process in patients with Philadelphia chromosome negative myeloproliferative neoplasms.
    Leukemia, 2009, Volume: 23, Issue:9

    Topics: Antigens, CD34; Cells, Cultured; Erlotinib Hydrochloride; Humans; Janus Kinase 2; Mast Cells; Mutation; Polycythemia Vera; Primary Myelofibrosis; Quinazolines; Receptors, Thrombopoietin; Thrombocythemia, Essential

2009
[Essential thrombocythaemia and other myeloproliferative disorders with thrombocythaemia treated with Thromboreductin. A report from the database of register for the 1st quarter of 2010].
    Vnitrni lekarstvi, 2010, Volume: 56, Issue:6

    Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Count; Polycythemia Vera; Primary Myelofibrosis; Quinazolines; Thrombocythemia, Essential

2010
[Effect of erlotinib on proliferation and differentiation of JAK2V617F-positive cells in vitro].
    Zhongguo shi yan xue ye xue za zhi, 2012, Volume: 20, Issue:2

    Topics: Cell Differentiation; Cell Proliferation; Cells, Cultured; Erlotinib Hydrochloride; Hematopoietic Stem Cells; Humans; Janus Kinase 2; Polycythemia Vera; Quinazolines

2012
Anagrelide-associated cardiomyopathy in polycythemia vera and essential thrombocythemia.
    Haematologica, 2004, Volume: 89, Issue:11

    Topics: Cardiomyopathies; Female; Humans; Platelet Aggregation Inhibitors; Polycythemia Vera; Quinazolines; Thrombocythemia, Essential

2004
Erlotinib effectively inhibits JAK2V617F activity and polycythemia vera cell growth.
    The Journal of biological chemistry, 2007, Feb-09, Volume: 282, Issue:6

    Topics: Amino Acid Substitution; Animals; Cell Line, Tumor; Cell Proliferation; Drug Delivery Systems; Enzyme Activation; Erlotinib Hydrochloride; Growth Inhibitors; Hematopoietic Stem Cells; Humans; Janus Kinase 2; Jurkat Cells; Mice; Phenylalanine; Polycythemia Vera; Protein Kinase Inhibitors; Quinazolines; Valine

2007
[Essential thrombocytemia and other myeloproliferations with thrombocytemia in the data of the register of patients treated with Thromboreductin till the end of 2006].
    Vnitrni lekarstvi, 2007, Volume: 53, Issue:6

    Topics: Adult; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Myeloproliferative Disorders; Platelet Aggregation Inhibitors; Platelet Count; Polycythemia Vera; Quinazolines; Thrombocytosis

2007
[Chronic myeloproliferative diseases].
    Orvosi hetilap, 1998, Jul-26, Volume: 139, Issue:30

    Topics: Chronic Disease; Female; Fibrinolytic Agents; Humans; Interferons; Leukemia, Myeloid; Male; Myeloproliferative Disorders; Polycythemia Vera; Primary Myelofibrosis; Quinazolines; Thrombocythemia, Essential

1998
Anagrelide-induced cardiomyopathy.
    Pharmacotherapy, 2000, Volume: 20, Issue:10

    Topics: Cardiomyopathies; Female; Humans; Middle Aged; Platelet Aggregation Inhibitors; Polycythemia Vera; Quinazolines

2000
Hydroxyurea and periodicity in myeloproliferative disease.
    European journal of haematology, 2001, Volume: 66, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Blood Cell Count; Busulfan; Female; Hemoglobins; Humans; Hydroxyurea; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukocyte Count; Lymphocytes; Male; Monocytes; Neutrophils; Periodicity; Platelet Count; Polycythemia Vera; Quinazolines

2001
Anagrelide: a new drug for treating thrombocytosis.
    The New England journal of medicine, 1988, May-19, Volume: 318, Issue:20

    Topics: Adult; Aged; Female; Hematopoietic Stem Cells; Humans; Male; Middle Aged; Myeloproliferative Disorders; Platelet Aggregation Inhibitors; Platelet Count; Polycythemia Vera; Quinazolines; Thrombocythemia, Essential; Thrombocytosis

1988