Page last updated: 2024-08-21

quinazolines and Parkinson Disease

quinazolines has been researched along with Parkinson Disease in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's3 (37.50)24.3611
2020's3 (37.50)2.80

Authors

AuthorsStudies
Campbell, MV; Davies, SB; Fiolek, TJ; Magyar, CL; Mosey, RA; Savich, CJ; Tepe, JJ; Wall, TJ1
Liu, L; Narayanan, NS; Pottegård, A; Simmering, JE; Welsh, MJ1
Gao, H; Jiang, S; Mao, J; Wang, D; Yang, X1
Avale, ME; Bernardi, MA; Bordone, MP; Damianich, A; Ferrario, JE; Gershanik, OS; Gomez, G; Hanger, DP; Isaja, L; Sanz-Blasco, S; Taravini, IR1
Burbulla, LF; Jeon, S; Jiang, W; Krainc, D; Oevel, K; Silverman, RB; Ysselstein, D; Zheng, J1
Chen, L; Krainc, D; Schwake, M; Silverman, RB; Zheng, J1
Bhatnagar, SP; Laddha, SS1
Agid, Y; Cash, R; Lasbennes, F; Sercombe, R; Seylaz, J1

Other Studies

8 other study(ies) available for quinazolines and Parkinson Disease

ArticleYear
Dihydroquinazolines enhance 20S proteasome activity and induce degradation of α-synuclein, an intrinsically disordered protein associated with neurodegeneration.
    Bioorganic & medicinal chemistry letters, 2021, 03-15, Volume: 36

    Topics: alpha-Synuclein; Dose-Response Relationship, Drug; Humans; Intrinsically Disordered Proteins; Molecular Structure; Parkinson Disease; Proteasome Endopeptidase Complex; Quinazolines; Structure-Activity Relationship

2021
Association of Glycolysis-Enhancing α-1 Blockers With Risk of Developing Parkinson Disease.
    JAMA neurology, 2021, 04-01, Volume: 78, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Aged; Aged, 80 and over; Cohort Studies; Databases, Factual; Denmark; Doxazosin; Female; Follow-Up Studies; Glycolysis; Humans; Male; Middle Aged; Parkinson Disease; Prazosin; Quinazolines; Registries; Risk Factors; Tamsulosin; United States

2021
NF‑κB is negatively associated with Nurr1 to reduce the inflammatory response in Parkinson's disease.
    Molecular medicine reports, 2021, Volume: 23, Issue:6

    Topics: Animals; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Nuclear Receptor Subfamily 4, Group A, Member 2; Parkinson Disease; PC12 Cells; Quinazolines; Rats; Synucleins; Transcription Factor RelA; Tumor Necrosis Factor-alpha; Tyrosine 3-Monooxygenase

2021
The Kinase Fyn As a Novel Intermediate in L-DOPA-Induced Dyskinesia in Parkinson's Disease.
    Molecular neurobiology, 2018, Volume: 55, Issue:6

    Topics: Animals; Benzodioxoles; Dyskinesia, Drug-Induced; Female; Levodopa; Male; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Movement; Neostriatum; Parkinson Disease; Phosphorylation; Protein Subunits; Proto-Oncogene Proteins c-fyn; Quinazolines; Receptors, N-Methyl-D-Aspartate; Tyrosine 3-Monooxygenase

2018
Conversion of Quinazoline Modulators from Inhibitors to Activators of β-Glucocerebrosidase.
    Journal of medicinal chemistry, 2019, 02-14, Volume: 62, Issue:3

    Topics: Dopaminergic Neurons; Enzyme Activators; Enzyme Inhibitors; Gaucher Disease; Glucosylceramidase; Humans; Methylation; Parkinson Disease; Quinazolines; Structure-Activity Relationship

2019
Design and Synthesis of Potent Quinazolines as Selective β-Glucocerebrosidase Modulators.
    Journal of medicinal chemistry, 2016, Sep-22, Volume: 59, Issue:18

    Topics: Cell Line; Drug Design; Enzyme Stability; Gaucher Disease; Glucosylceramidase; Humans; Parkinson Disease; Quinazolines

2016
A new therapeutic approach in Parkinson's disease: some novel quinazoline derivatives as dual selective phosphodiesterase 1 inhibitors and anti-inflammatory agents.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Animals; Anti-Inflammatory Agents; Child, Preschool; Cyclic Nucleotide Phosphodiesterases, Type 1; Drug Evaluation, Preclinical; Edema; Humans; Parkinson Disease; Phosphodiesterase Inhibitors; Quinazolines; Rats; Stomach Ulcer; Structure-Activity Relationship

2009
Adrenergic receptors on cerebral microvessels in control and parkinsonian subjects.
    Life sciences, 1985, Aug-12, Volume: 37, Issue:6

    Topics: Aged; Alprenolol; Capillaries; Cerebrovascular Circulation; Clonidine; Dihydroalprenolol; Humans; Kinetics; Parkinson Disease; Prazosin; Quinazolines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Reference Values

1985