quinazolines has been researched along with Osteoarthritis in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (38.89) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 6 (33.33) | 24.3611 |
| 2020's | 3 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| An, X; Jia, ZW; Su, YX; Wang, XJ; Yu, JP; Zhang, J | 1 |
| Chen, L; Gong, Y; Hong, Z; Jiang, T; Mi, S; Qiu, J; Wang, Z; Ye, J; Zhang, W; Zheng, X; Zhu, Z | 1 |
| Lu, X; Luo, S; Pang, C; Qin, H; Wen, L; Zhu, B | 1 |
| Bai, X; Cai, D; Huang, B; Jiang, W; Jiang, Y; Li, K; Li, M; Liu, A; Shen, J; Song, Q; Xu, S; Zhang, Y | 1 |
| An, C; Chen, P; Chen, Y; Lei, X; Ouyang, H; Pan, Z; Qin, T; Sun, H; Wu, H; Wu, Y; Yu, D; Yuan, C; Zhang, S; Zhang, X; Zou, W | 1 |
| Arndt, K; Corradini, L; Doods, H; Hirsch, S; Just, S | 1 |
| Kanzaki, N; Kori, M; Kuno, H; Mototani, H; Naito, T; Nara, H; Oki, H; Santou, T; Sato, K; Terauchi, J; Uchikawa, O; Yamamoto, Y | 1 |
| Appleton, CT; Beier, F; Mort, JS; Pest, MA; Pitelka, V; Usmani, SE | 1 |
| Ishikawa, M; Miyaki, S; Nakasa, T; Ochi, M; Takada, T | 1 |
| Cheng, AC; de la Cruz, E; Habeski, WM; Kablaoui, NM; Loh, C; Patel, SD | 1 |
| Kris, MG; Moryl, N; Obbens, EA; Ozigbo, OH | 1 |
| Serry, MM | 1 |
| Bryans, R; Huskisson, EC; Scott, J | 1 |
| Wheatley, D | 1 |
| Sfikakis, P; Tsachalos, P | 1 |
| Lepistö, PV; Vainio, JT | 1 |
| Allan, R; Bleicher, M | 2 |
7 trial(s) available for quinazolines and Osteoarthritis
| Article | Year |
|---|---|
Proquazone ('Biarison') in osteoarthritis of the knee: a double-blind, dose comparison trial.
Topics: Adult; Anti-Inflammatory Agents; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Knee Joint; Male; Middle Aged; Osteoarthritis; Quinazolines; Stomach Diseases | 1980 |
Fluproquazone for osteoarthritis.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Indomethacin; Male; Middle Aged; Osteoarthritis; Pain; Quinazolines; Quinazolinones; Random Allocation | 1981 |
Analgesic properties of fluproquazone.
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Dextropropoxyphene; Drug Combinations; Female; Humans; Male; Middle Aged; Osteoarthritis; Quinazolines; Quinazolinones | 1982 |
[Proquazone in the treatment of osteoarthritis of the knee: a double-blind comparison with naproxen (author's transl)].
Topics: Aged; Anti-Inflammatory Agents; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Humans; Joint Diseases; Knee Joint; Male; Middle Aged; Naproxen; Osteoarthritis; Quinazolines | 1977 |
A long-term comparison of proquazone and naproxen in the treatment of osteoarthritis of the hip.
Topics: Adult; Aged; Anti-Inflammatory Agents; Clinical Trials as Topic; Drug Evaluation; Female; Hip Joint; Humans; Male; Middle Aged; Naproxen; Osteoarthritis; Quinazolines; Time Factors | 1978 |
Biarison in the treatment of degenerative joint diseases: comparison with indomethacin and placebo.
Topics: Adult; Aged; Anti-Inflammatory Agents; Central Nervous System Diseases; Double-Blind Method; Drug Tolerance; Female; Humans; Indomethacin; Male; Middle Aged; Osteoarthritis; Placebos; Quinazolines | 1977 |
[The management of osteoarthritic conditions with biarison (author's transl)].
Topics: Double-Blind Method; Drug Evaluation; Humans; Osteoarthritis; Quinazolines | 1977 |
11 other study(ies) available for quinazolines and Osteoarthritis
| Article | Year |
|---|---|
Attenuation of cartilage pathogenesis in osteoarthritis by blocking the phosphorylation of tyrosine kinase Fyn to β-catenin, AZD0530.
Topics: Animals; Benzodioxoles; beta Catenin; Cartilage, Articular; Cells, Cultured; Chondrocytes; Osteoarthritis; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-fyn; Quinazolines; Rats; Wnt Signaling Pathway | 2022 |
AZ-628 delays osteoarthritis progression via inhibiting the TNF-α-induced chondrocyte necroptosis and regulating osteoclast formation.
Topics: Animals; Chondrocytes; Mice; Necroptosis; NF-kappa B; Osteoarthritis; Osteoclasts; Quinazolines; Tumor Necrosis Factor-alpha | 2022 |
Sotrastaurin, a PKC inhibitor, attenuates RANKL-induced bone resorption and attenuates osteochondral pathologies associated with the development of OA.
Topics: Animals; Bone and Bones; Bone Resorption; Cartilage Diseases; Cartilage, Articular; Cattle; Cell Differentiation; Female; Male; Mice; Mice, Inbred C57BL; Osteoarthritis; Osteoclasts; Protein Kinase C; Pyrroles; Quinazolines; RANK Ligand; Signal Transduction | 2020 |
Tyrosine kinase Fyn promotes osteoarthritis by activating the β-catenin pathway.
Topics: Aging; Animals; Arthritis, Experimental; Benzodioxoles; beta Catenin; Cartilage, Articular; Cells, Cultured; Chondrocytes; Enzyme Inhibitors; Gene Knockout Techniques; Humans; Mice, Knockout; Molecular Targeted Therapy; Osteoarthritis; Proto-Oncogene Proteins c-fyn; Pyrazoles; Pyrimidines; Quinazolines; Signal Transduction | 2018 |
Gefitinib for Epidermal Growth Factor Receptor Activated Osteoarthritis Subpopulation Treatment.
Topics: Animals; Cartilage, Articular; Collagen Type II; Disease Models, Animal; ErbB Receptors; Gefitinib; Humans; Mice; Mice, Transgenic; Osteoarthritis; Precision Medicine; Quinazolines; Signal Transduction | 2018 |
The CGRP receptor antagonist BIBN4096BS peripherally alleviates inflammatory pain in rats.
Topics: Administration, Topical; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Freund's Adjuvant; Inflammation; Ketorolac; Male; Morphine; Neurons; Osteoarthritis; Pain; Pain Measurement; Piperazines; Quinazolines; Rats; Rats, Wistar; Spinal Cord | 2013 |
Discovery of novel, highly potent, and selective quinazoline-2-carboxamide-based matrix metalloproteinase (MMP)-13 inhibitors without a zinc binding group using a structure-based design approach.
Topics: Animals; Benzoates; Binding Sites; Crystallography, X-Ray; Humans; Inhibitory Concentration 50; Matrix Metalloproteinase 13; Matrix Metalloproteinase Inhibitors; Osteoarthritis; Quinazolines; Rats; Structure-Activity Relationship | 2014 |
Reduction in disease progression by inhibition of transforming growth factor α-CCL2 signaling in experimental posttraumatic osteoarthritis.
Topics: Animals; Benzoxazines; Cartilage, Articular; Chemokine CCL2; Disease Models, Animal; Disease Progression; Male; Osteoarthritis; Quinazolines; Rats; Rats, Sprague-Dawley; Signal Transduction; Spiro Compounds; Transforming Growth Factor alpha; Tyrphostins; Up-Regulation; Wounds and Injuries | 2015 |
Attenuation of cartilage degeneration by calcitonin gene-related paptide receptor antagonist via inhibition of subchondral bone sclerosis in osteoarthritis mice.
Topics: Animals; Arthritis, Experimental; Bone Remodeling; Calcitonin Gene-Related Peptide Receptor Antagonists; Cartilage; Cells, Cultured; Dipeptides; Drug Evaluation, Preclinical; Humans; Male; Mice, Inbred C57BL; Osteoarthritis; Osteogenesis; Piperazines; Quinazolines | 2016 |
Quinazolin-4-piperidin-4-methyl sulfamide PC-1 inhibitors: alleviating hERG interactions through structure based design.
Topics: Drug Design; Enzyme Inhibitors; Ether-A-Go-Go Potassium Channels; Humans; Long QT Syndrome; Osteoarthritis; Phosphoric Diester Hydrolases; Piperidines; Protein Binding; Pyrophosphatases; Quinazolines; Sulfonamides | 2009 |
Analgesic effect of gefitinib in the treatment of non-small cell lung cancer.
Topics: Aged; Analgesics; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Female; Gefitinib; Humans; Lung Neoplasms; Osteoarthritis; Quinazolines | 2006 |