Page last updated: 2024-08-21

quinazolines and Obesity

quinazolines has been researched along with Obesity in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (19.05)18.2507
2000's6 (28.57)29.6817
2010's10 (47.62)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Chu, Y; Gu, P; Hui, X; Lin, S; Liu, X; Loomes, K; Mao, L; Nie, T; Tang, S; Wu, D; Xu, Y; Zhang, Y; Zhao, S; Zhao, X1
Ahmad, H; Dogra, S; Dwivedi, AK; Jaiswal, S; Kumar, A; Lal, J; Pasam, VR; Rashid, M; Shukla, M; Siddiqi, MI; Singh, K; Singh, M; Singh, SK; Sona, C; Thakur, RK; Tripathi, RP; Umrao, D; Wahajuddin, M; Yadav, A; Yadav, PN1
Hansen, G; Hansen, HH; Jelsing, J; Klein, T; Mark, M; Paulsen, S; Vrang, N1
Kobayashi, Y1
Fang, Q; Li, W; Li, X; Liang, G; Lin, F; Wang, L; Wang, Y; Zhang, Y; Zheng, C; Zhong, P; Zou, C1
Beck-Nielsen, H; Byrjalsen, I; Christiansen, C; Henriksen, K; Karsdal, MA; Larsen, LK; Madsen, AN; Nielsen, RH1
Chae, S; Han, MD; Kim, SJ; Lee, S; Lee, SJ; Mar, W; Nam, KW1
Bak, EJ; Cha, JH; Kim, JM; Park, HG; Yoo, YJ1
Akanuma, M; Fujiya, M; Hiranaka, N; Ieko, M; Kanazawa, K; Kohgo, Y; Naito, S; Oka, K; Suzuki, T; Takahashi, N; Yoshida, M; Yoshizaki, T; Yui, T1
Cheetham, S; Ittrich, C; Kassubek, J; Klein, T; Mark, M; Mayoux, E; Mueller, HP; Niessen, HG; Stiller, D1
Blüher, M; Kern, M; Klein, T; Klöting, N; Mark, M; Niessen, HG; Stiller, D; Thomas, L1
Birmingham, GD; Cheetham, SC; Dickinson, K; Grempler, R; Headland, KR; Hocher, B; Klein, T; Mark, M; Rowley, HL; Vickers, SP1
Darlöf, E; Darsalia, V; Klein, T; Nyström, T; Olverling, A; Ortsäter, H; Patrone, C; Sjöholm, Å; Wolbert, P1
Ihara, S; Kawana, M; Sakai, R; Shimamoto, K; Watanabe, H1
Kobayashi, Y; Kontani, Y; Mori, N; Sato, Y; Wang, T; Wang, Y; Yamashita, H1
Chen, Z; Christofi, FL; Cooke, HJ; Grants, I; Melvin, WS; Mikami, DJ; Needleman, BJ; Wang, Y; Wunderlich, JE; Yu, JG1
Bönner, G; Chrosch, R; Schmieder, R; Weidinger, G1
Rabl, W; Standl, E; Stemplinger, J; Stiegler, H; Weichenhain, B; Ziegler, AG1
Hoshikuma, K; Kamiya, T; Kizaki, M; Kobayashi, Y; Nakano, Y; Yokoo, Y1
Asakura, Y; Harano, Y; Hirose, J; Kageyama, A; Omae, T; Sato, A; Suzuki, M1
Fujioka, S; Kawamoto, T; Keno, Y; Kobatake, T; Matsuzawa, Y; Tarui, S; Tokunaga, K; Watanabe, Y; Yoshida, H1

Trials

2 trial(s) available for quinazolines and Obesity

ArticleYear
An alpha1-receptor blocker reduces plasma leptin levels in hypertensive patients with obesity and hyperleptinemia.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2006, Volume: 29, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Adult; Aged; Blood Pressure; Body Mass Index; Delayed-Action Preparations; Fatty Acids, Nonesterified; Female; Heart Rate; Humans; Hypertension; Insulin Resistance; Leptin; Male; Middle Aged; Obesity; Quinazolines; Receptors, Leptin; Treatment Outcome

2006
Effect of bunazosin and atenolol on glucose metabolism in obese, nondiabetic patients with primary hypertension.
    Cardiovascular drugs and therapy, 1997, Volume: 11, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Blood Glucose; Double-Blind Method; Female; Glucose; Glucose Tolerance Test; Humans; Hypertension; Insulin; Lipids; Male; Middle Aged; Obesity; Quinazolines

1997

Other Studies

19 other study(ies) available for quinazolines and Obesity

ArticleYear
The natural compound rutaecarpine promotes white adipocyte browning through activation of the AMPK-PRDM16 axis.
    Biochemical and biophysical research communications, 2021, 03-19, Volume: 545

    Topics: Adipocytes, Beige; Adipocytes, White; AMP-Activated Protein Kinases; Animals; Biological Products; Disease Models, Animal; DNA-Binding Proteins; Drug Evaluation, Preclinical; In Vitro Techniques; Indole Alkaloids; Male; Mice; Mice, Transgenic; Models, Biological; Obesity; Oxygen Consumption; Quinazolines; Signal Transduction; Thermogenesis; Transcription Factors

2021
Novel Tetrahydroquinazolinamines as Selective Histamine 3 Receptor Antagonists for the Treatment of Obesity.
    Journal of medicinal chemistry, 2019, 05-09, Volume: 62, Issue:9

    Topics: Animals; Anti-Obesity Agents; Blood Glucose; Diet, High-Fat; HEK293 Cells; Histamine H3 Antagonists; Humans; Male; Mice, Inbred C57BL; Molecular Structure; Obesity; Proto-Oncogene Proteins c-fos; Quinazolines; Receptors, Histamine H3; Stereoisomerism; Structure-Activity Relationship; Weight Loss

2019
The DPP-IV inhibitor linagliptin and GLP-1 induce synergistic effects on body weight loss and appetite suppression in the diet-induced obese rat.
    European journal of pharmacology, 2014, Oct-15, Volume: 741

    Topics: Animals; Appetite Depressants; Body Weight; Diet, High-Fat; Dietary Sucrose; Dipeptidyl-Peptidase IV Inhibitors; Drug Synergism; Drug Therapy, Combination; Glucagon-Like Peptide 1; Linagliptin; Male; Obesity; Purines; Quinazolines; Rats; Rats, Sprague-Dawley; Weight Loss

2014
[Effects of evodiamine, a major alkaloid of Goshuyu (Evodia Fruits), on TRPV1].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2015, Volume: 146, Issue:3

    Topics: Body Temperature; Evodia; Fruit; Humans; Obesity; Pain Management; Quinazolines; TRPV Cation Channels

2015
EGFR mediates hyperlipidemia-induced renal injury via regulating inflammation and oxidative stress: the detrimental role and mechanism of EGFR activation.
    Oncotarget, 2016, Apr-26, Volume: 7, Issue:17

    Topics: Animals; Cell Line; CSK Tyrosine-Protein Kinase; Enzyme Inhibitors; ErbB Receptors; Hyperlipidemias; Immunoblotting; Inflammation; Kidney; Male; Mice, Inbred C57BL; Mice, Knockout; Obesity; Oxidative Stress; Phosphorylation; Quinazolines; Rats; RNA Interference; src-Family Kinases; Tyrphostins

2016
A comparison of glycemic control, water retention, and musculoskeletal effects of balaglitazone and pioglitazone in diet-induced obese rats.
    European journal of pharmacology, 2009, Aug-15, Volume: 616, Issue:1-3

    Topics: Adipogenesis; Animals; Biomarkers; Blood Glucose; Body Weight; Bone and Bones; Bone Resorption; Diet; Glucose Tolerance Test; Hypoglycemic Agents; Lipid Metabolism; Magnetic Resonance Imaging; Male; Muscles; Obesity; Osteogenesis; Pioglitazone; PPAR alpha; Quinazolines; Rats; Thiazolidinediones; Water

2009
Rutecarpine ameliorates bodyweight gain through the inhibition of orexigenic neuropeptides NPY and AgRP in mice.
    Biochemical and biophysical research communications, 2009, Nov-20, Volume: 389, Issue:3

    Topics: Agouti-Related Protein; Animals; Cell Line; Down-Regulation; Eating; Hypothalamus; Indole Alkaloids; Mice; Mice, Inbred C57BL; Neurons; Neuropeptide Y; Obesity; Promoter Regions, Genetic; Quinazolines; Weight Gain

2009
Inhibitory effect of evodiamine alone and in combination with rosiglitazone on in vitro adipocyte differentiation and in vivo obesity related to diabetes.
    International journal of obesity (2005), 2010, Volume: 34, Issue:2

    Topics: Adipocytes; Adiponectin; Adipose Tissue; Animals; Blood Glucose; Cell Differentiation; Cell Line; Dietary Fats; Drug Therapy, Combination; Hypoglycemic Agents; Insulin; Liver; Mice; Mice, Inbred C57BL; Obesity; Plant Extracts; Quinazolines; Rosiglitazone; Thiazolidinediones; Weight Gain

2010
Suppression of lipin-1 expression increases monocyte chemoattractant protein-1 expression in 3T3-L1 adipocytes.
    Biochemical and biophysical research communications, 2011, Nov-11, Volume: 415, Issue:1

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Chemokine CCL2; Chemotaxis; Gene Expression; Insulin Resistance; Mice; NF-kappa B; Nuclear Proteins; Obesity; Phosphatidate Phosphatase; Protein Biosynthesis; Quinazolines; RNA, Messenger; RNA, Small Interfering; Salicylates

2011
Evaluation of body fat composition after linagliptin treatment in a rat model of diet-induced obesity: a magnetic resonance spectroscopy study in comparison with sibutramine.
    Diabetes, obesity & metabolism, 2012, Volume: 14, Issue:11

    Topics: Adiposity; Animals; Appetite Depressants; Body Composition; Cyclobutanes; Disease Models, Animal; Female; Linagliptin; Obesity; Purines; Quinazolines; Rats; Rats, Wistar

2012
Linagliptin improves insulin sensitivity and hepatic steatosis in diet-induced obesity.
    PloS one, 2012, Volume: 7, Issue:6

    Topics: Adipose Tissue; Animals; Diet; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Fatty Liver; Female; Glucose; Glucose Clamp Technique; Glucose Tolerance Test; Insulin; Insulin Resistance; Linagliptin; Liver; Mice; Mice, Inbred C57BL; Obesity; Purines; Quinazolines

2012
Effects of the DPP-4 inhibitor, linagliptin, in diet-induced obese rats: a comparison in naive and exenatide-treated animals.
    Clinical laboratory, 2012, Volume: 58, Issue:7-8

    Topics: Animals; Diet; Dipeptidyl-Peptidase IV Inhibitors; Female; Linagliptin; Obesity; Purines; Quinazolines; Rats; Rats, Wistar

2012
The DPP-4 inhibitor linagliptin counteracts stroke in the normal and diabetic mouse brain: a comparison with glimepiride.
    Diabetes, 2013, Volume: 62, Issue:4

    Topics: Animals; Diabetes Mellitus, Experimental; Dietary Fats; Dipeptidyl-Peptidase IV Inhibitors; Hypoglycemic Agents; Linagliptin; Male; Mice; Obesity; Purines; Quinazolines; Stroke; Sulfonylurea Compounds

2013
Evodiamine improves diet-induced obesity in a uncoupling protein-1-independent manner: involvement of antiadipogenic mechanism and extracellularly regulated kinase/mitogen-activated protein kinase signaling.
    Endocrinology, 2008, Volume: 149, Issue:1

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Anti-Obesity Agents; Cell Differentiation; Diet, Atherogenic; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Insulin; Ion Channels; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondrial Proteins; Obesity; Plant Extracts; Quinazolines; Signal Transduction; Uncoupling Protein 1

2008
Dual purinergic synaptic transmission in the human enteric nervous system.
    American journal of physiology. Gastrointestinal and liver physiology, 2008, Volume: 294, Issue:2

    Topics: Aniline Compounds; Calcium; Chloride Channels; Electric Stimulation; Enteric Nervous System; Fluorescent Dyes; Humans; Microscopy, Confocal; Nerve Fibers; Neurons; Obesity; Quinazolines; Receptors, Purinergic; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Submucous Plexus; Synaptic Transmission; Triazoles; Type C Phospholipases; Vasoactive Intestinal Peptide; Xanthenes

2008
[Alström syndrome--a rare disease of diabetic association].
    Medizinische Klinik (Munich, Germany : 1983), 1997, Mar-15, Volume: 92, Issue:3

    Topics: Adult; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diagnosis, Differential; DNA Mutational Analysis; Humans; Male; Obesity; Optic Atrophy; Quinazolines; Retinitis Pigmentosa; Second Messenger Systems; Syndrome

1997
Capsaicin-like anti-obese activities of evodiamine from fruits of Evodia rutaecarpa, a vanilloid receptor agonist.
    Planta medica, 2001, Volume: 67, Issue:7

    Topics: Adipose Tissue; Animals; Anti-Obesity Agents; Body Temperature; Body Weight; Capsaicin; Cholesterol; Fatty Acids, Nonesterified; Fruit; Japan; Lipid Metabolism; Lipolysis; Liver; Male; Medicine, East Asian Traditional; Mice; Mice, Inbred C3H; Obesity; Phytotherapy; Plant Extracts; Plants, Medicinal; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Drug; Rutaceae; Triglycerides

2001
Insulin insensitivity in nonobese, nondiabetic essential hypertension and its improvement by an alpha 1-blocker (bunazosin).
    American journal of hypertension, 1992, Volume: 5, Issue:12 Pt 1

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Apoproteins; Blood Glucose; Blood Pressure; Catecholamines; Diabetes Mellitus; Female; Glucose Tolerance Test; Humans; Hypertension; Insulin; Insulin Resistance; Lipids; Male; Middle Aged; Obesity; Quinazolines; Sodium

1992
Age-related changes in adrenergic alpha 1, alpha 2, and beta receptors of rat white fat cell membranes: an analysis using [3H]bunazosin as a novel ligand for the alpha 1 adrenoceptor.
    Journal of lipid research, 1991, Volume: 32, Issue:2

    Topics: Adipose Tissue; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aging; Animals; Binding Sites; Cell Membrane; Epididymis; Kinetics; Male; Obesity; Propanolamines; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine

1991