Compounds > quinazolines
Page last updated: 2024-08-21

quinazolines and Nasopharyngeal Carcinoma

quinazolines has been researched along with Nasopharyngeal Carcinoma in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's11 (73.33)24.3611
2020's4 (26.67)2.80

Authors

AuthorsStudies
Bian, X; Guo, W; He, X; Huang, S; Jiang, N; Jiang, X; Li, F; Liu, J; Song, D; Sun, X; Wang, B; Wang, F; Wu, J; Yan, P; Yin, H; Yin, L; Zhang, F; Zhou, C; Zhou, H1
Bao, X; Deng, A; Li, Q; Wang, L; Wang, M; Xiang, Y; Yu, W; Zhang, B; Zhang, Y1
Ding, WJ; Dong, QH; Wang, W; Yang, HH; Zhu, J1
Bao, X; Chen, C; Deng, A; Deng, P; He, M; Ji, D; Li, Q; Liang, X; Lu, Y; Pi, H; Tan, G; Wang, L; Yu, Z; Zhang, L; Zhou, Z1
Liu, F; Liu, Y; Luo, H; Wu, Y; Zhao, Y1
Deng, XB; Jin, ZR; Li, XQ; Liu, QZ; Liu, Y; Ma, L; Miao, XB; Sun, DX; Testa, JR; Wu, Y; Xiao, GH; Yao, KT; Zhang, G1
Lin, J; Wang, L; Xie, B; Xu, T; Zhang, W; Zheng, J; Zhou, J1
Chow, JP; Hong, MJ; Li, J; Ma, HT; Mak, JP; Man, WY; Poon, RY1
Ai, P; Li, J; Peng, X; Wang, L; Zeng, Y; Zhang, Q1
Cui, Y; Li, X; Liu, H; Wang, D; Xu, T; Yin, B; Zhang, C; Zhang, Y1
Fang, W; Tian, Y; Xue, C; Zhan, J; Zhang, J; Zhang, L; Zhao, Y1
Chen, N; Huang, P; Lin, Z; Liu, L; Peng, P; Tang, C; Wang, Z1
Huang, W; Jia, H; Ma, J; Tan, L; Wu, J; Yan, H; Yang, S; Zeng, M; Zhu, X; Zuo, Y1
Chan, AT; Cheng, SH; Ho, K; Lau, CP; Lei, KI; Lui, VW; Mok, TS; Ng, MH; Tsang, CM; Tsao, SW1
He, BF; Huang, BY; Luo, RC; Sun, AM; Wang, WJ; Zheng, XK1

Reviews

1 review(s) available for quinazolines and Nasopharyngeal Carcinoma

ArticleYear
ZD6474, a small molecule tyrosine kinase inhibitor, potentiates the anti-tumor and anti-metastasis effects of radiation for human nasopharyngeal carcinoma.
    Current cancer drug targets, 2010, Volume: 10, Issue:6

    Topics: Animals; Apoptosis; Carcinoma; Chemotherapy, Adjuvant; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Neoplasm Metastasis; Piperidines; Protein Kinase Inhibitors; Quinazolines

2010

Trials

2 trial(s) available for quinazolines and Nasopharyngeal Carcinoma

ArticleYear
Raltitrexed versus 5-fluorouracil with cisplatin and concurrent radiotherapy for locally advanced nasopharyngeal carcinoma: An open labeled, randomized, controlled, and multicenter clinical trial.
    Cancer medicine, 2020, Volume: 9, Issue:17

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Chemoradiotherapy; Chi-Square Distribution; Cisplatin; Female; Fluorouracil; Humans; Male; Middle Aged; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Progression-Free Survival; Quinazolines; Stomatitis; Thiophenes; Young Adult

2020
Metastatic nasopharyngeal carcinoma outcomes in patients on cisplatin with nolatrexed or 5-fluorouracil.
    Oncology research and treatment, 2014, Volume: 37, Issue:10

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Disease-Free Survival; Female; Fluorouracil; Humans; Male; Middle Aged; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Recurrence, Local; Quinazolines; Survival Rate; Treatment Outcome

2014

Other Studies

12 other study(ies) available for quinazolines and Nasopharyngeal Carcinoma

ArticleYear
BIX-01294-enhanced chemosensitivity in nasopharyngeal carcinoma depends on autophagy-induced pyroptosis.
    Acta biochimica et biophysica Sinica, 2020, Oct-19, Volume: 52, Issue:10

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Autophagy-Related Protein 5; Azepines; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; Cell Survival; Chloroquine; Cisplatin; CRISPR-Cas Systems; Gene Knockout Techniques; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Microtubule-Associated Proteins; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Pyroptosis; Quinazolines; Receptors, Estrogen; Signal Transduction

2020
[Icotinib combined with radiotherapy for childhood nasopharyngeal carcinoma: A case report and review of the literature].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2020, Oct-23, Volume: 42, Issue:10

    Topics: Child; Combined Modality Therapy; Crown Ethers; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Prognosis; Quinazolines; Radiotherapy; Radiotherapy Dosage; Treatment Outcome

2020
BIX-01294, a G9a inhibitor, suppresses cell proliferation by inhibiting autophagic flux in nasopharyngeal carcinoma cells.
    Investigational new drugs, 2021, Volume: 39, Issue:3

    Topics: Antineoplastic Agents; Autophagosomes; Azepines; Cell Line, Tumor; Cell Physiological Phenomena; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Humans; Lysosomal Membrane Proteins; Lysosomal-Associated Membrane Protein 2; Lysosomes; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Quinazolines; RNA, Small Interfering

2021
Construction of EGFR peptide gefitinib/quantum dots long circulating polymeric liposomes for treatment and detection of nasopharyngeal carcinoma.
    Biochemical and biophysical research communications, 2017, 08-19, Volume: 490, Issue:2

    Topics: Antineoplastic Agents; Carcinoma; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Gefitinib; Humans; Liposomes; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Peptides; Polymers; Quantum Dots; Quinazolines; Structure-Activity Relationship; Tumor Cells, Cultured

2017
Cancer stem-like cell properties are regulated by EGFR/AKT/β-catenin signaling and preferentially inhibited by gefitinib in nasopharyngeal carcinoma.
    The FEBS journal, 2013, Volume: 280, Issue:9

    Topics: Animals; Antineoplastic Agents; beta Catenin; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cisplatin; ErbB Receptors; Gefitinib; Gene Knockdown Techniques; Homeodomain Proteins; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Nanog Homeobox Protein; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Transplantation; Neoplastic Stem Cells; Proto-Oncogene Proteins c-akt; Quinazolines; Side-Population Cells; Signal Transduction; Spheroids, Cellular; Xenograft Model Antitumor Assays

2013
Co-inhibition of polo-like kinase 1 and Aurora kinases promotes mitotic catastrophe.
    Oncotarget, 2015, Apr-20, Volume: 6, Issue:11

    Topics: Animals; Antineoplastic Agents; Aurora Kinase A; Aurora Kinase B; Carcinoma; Cell Cycle Proteins; Cyclohexanecarboxylic Acids; Drug Synergism; Female; HeLa Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Mitosis; Molecular Targeted Therapy; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Organophosphates; Polo-Like Kinase 1; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pteridines; Quinazolines; Thiazoles; Tumor Cells, Cultured

2015
Evodiamine inhibits the migration and invasion of nasopharyngeal carcinoma cells in vitro via repressing MMP-2 expression.
    Cancer chemotherapy and pharmacology, 2015, Volume: 76, Issue:6

    Topics: Blotting, Western; Carcinoma; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Survival; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Molecular Structure; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; NF-kappa B; Phosphorylation; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction

2015
Intravoxel Incoherent Motion Diffusion-weighted Magnetic Resonance Imaging for Monitoring the Early Response to ZD6474 from Nasopharyngeal Carcinoma in Nude Mouse.
    Scientific reports, 2015, Nov-17, Volume: 5

    Topics: Animals; Antineoplastic Agents; Carcinoma; Cell Line, Tumor; Diffusion Magnetic Resonance Imaging; Humans; Image Processing, Computer-Assisted; Ki-67 Antigen; Mice; Mice, Nude; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Piperidines; Quinazolines; Radiography; Transplantation, Heterologous

2015
In vitro and in vivo efficacy of afatinib as a single agent or in combination with gemcitabine for the treatment of nasopharyngeal carcinoma.
    Drug design, development and therapy, 2016, Volume: 10

    Topics: Afatinib; Animals; Antineoplastic Agents; Carcinoma; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Dose-Response Relationship, Drug; Gemcitabine; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasms, Experimental; Quinazolines; Structure-Activity Relationship

2016
Inhibition of eEF-2 kinase sensitizes human nasopharyngeal carcinoma cells to lapatinib-induced apoptosis through the Src and Erk pathways.
    BMC cancer, 2016, 10-19, Volume: 16, Issue:1

    Topics: Apoptosis; Carcinoma; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Drug Synergism; Elongation Factor 2 Kinase; Extracellular Signal-Regulated MAP Kinases; Gene Silencing; Humans; Lapatinib; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Protein Kinase Inhibitors; Quinazolines; RNA Interference; Signal Transduction; src-Family Kinases

2016
Anti-invasion, anti-proliferation and anoikis-sensitization activities of lapatinib in nasopharyngeal carcinoma cells.
    Investigational new drugs, 2011, Volume: 29, Issue:6

    Topics: Anoikis; Antineoplastic Agents; Carcinoma; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Humans; Lapatinib; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Poly(ADP-ribose) Polymerases; Protein Kinase Inhibitors; Quinazolines; Receptor, ErbB-2

2011
[Gefitinib enhances the radiosensitivity of nasopharyngeal carcinoma cell line CNE2 in vitro].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2011, Volume: 31, Issue:6

    Topics: Apoptosis; Carcinoma; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Flow Cytometry; Gefitinib; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Quinazolines; Radiation Tolerance

2011