Page last updated: 2024-08-21

quinazolines and Muscle Contraction

quinazolines has been researched along with Muscle Contraction in 94 studies

Research

Studies (94)

Timeframe	Studies, this research(%)	All Research%
pre-1990	50 (53.19)	18.7374
1990's	18 (19.15)	18.2507
2000's	19 (20.21)	29.6817
2010's	4 (4.26)	24.3611
2020's	3 (3.19)	2.80

Authors

Authors	Studies
Ciotkowska, A; Erlander, MG; Hennenberg, M; Li, B; Ridinger, M; Rutz, B; Stief, CG; Tamalunas, A; Waidelich, R; Wang, R; Wang, X	1
Alsufyani, HA; Docherty, JR; McCormick, PA	1
An, P; Ding, Y; Luo, H; Ren, H; Tan, W; Yuan, F	1
Chen, DP; Lin, Y; Liu, FF; Lv, BC; Peng, JY; Wang, JY; Xiong, YJ	1
Ciotkowska, A; Gratzke, C; Hennenberg, M; Herlemann, A; Janich, S; Liu, C; Rutz, B; Stief, CG; Strittmatter, F; Tamalunas, A; Waidelich, R; Wang, Y	1
Agrawal, KC; Chandra, S; Gur, S; Hellstrom, WJ; Kadowitz, PJ; Koka, PS; Sikka, SC	1
Adam, A; Bouthillier, J; Koumbadinga, GA; Marceau, F; Petitclerc, E	1
Hoyano, Y; Kobayashi, S; Kusama, H; Maruyama, K; Tomiyama, Y; Yamazaki, Y	1
Cho, JS; Choo, MS; Han, JY; Kim, JC; Lee, KS; Lee, YS; Song, K	1
Abdulkadir, NA; Cetinkaya, M; Demirturk, K; Gur, S; Hellstrom, WJ; Karabakan, M; Ozgur-Akdemir, A; Volkan-Oztekin, C	1
Carter, RW; Kanagy, NL	1
Hayakawa, H; Hirata, Y; Kakoki, M; Kangawa, K; Kitamura, T; Kurihara, H; Matsuo, H; Nagai, R; Nagata, D; Nishimatsu, H; Sata, M; Satonaka, H; Shindo, T; Suzuki, E; Takeda, R	1
Alexandre, L; Allard, J; Bernabe, J; Droupy, S; Giuliano, F	1
Brooke-Smith, M; Saccone, GT; Sandstrom, P; Svanvik, J; Toouli, J; Woods, CM	1
Dessi, C; Marchese, G; Mongeau, R; Pani, L; Ruiu, S; Tambaro, S	1
Angeli, P; Buccioni, M; Giardinà, D; Gulini, U; Marucci, G; Melchiorre, C; Sagratini, G; Testa, R	1
Bertagnolli, MM; Carothers, AM; Hunt, DH; Javid, SH; Moran, AE; Redston, M	1
Mulè, F; Serio, R; Zizzo, MG	1
Albo, G; Berardi, F; Colabufo, NA; Contino, M; de Rienzo, G; Niso, M; Pagliarulo, A; Pagliarulo, V; Perrone, R	1
Blagbrough, IS; Farghaly, HS; Medina-Tato, DA; Watson, ML	1
Aviado, DM; Folle, LE; Pisanty, J	1
Clancy, RL; Gilmore, JP; Graham, TP; Powell, WJ	1
Carr, PW; Cooper, T; Daggett, WM; Lish, PM; Nugent, GG; Powers, PC	1
Fagbemi, SO; Salako, LA	2
Fujino, S; Hoshi, K	1
Caine, M; Mazouz, B; Shapiro, A	1
Shoji, T	1
Ludvig, N; Vizi, ES	1
Ishikawa, S	1
Chen, CX; Jin, RM; Li, YK; Wang, YM	1
Felix, W; Greif, J	1
Doggrell, SA	1
Crowley, HJ; Levitan, P; Tilley, JW; Welton, AF	1
Folly, G; Ludvig, N; Rónai, AZ; Vizi, ES	1
Miyazaki, M; Nakajima, M; Okamura, T; Toda, N	1
Crowley, HJ; Folco, G; Viganó, T; Welton, AF	1
Barcelon-Yang, C; Brown, BS; Matier, WL; Reynolds, RD; Stout, DM	1
Hong, E	1
Adenekan, OO; Tayo, FM	1
De Mey, JG; Rusch, NJ; Vanhoutte, PM	1
Hong, E; Ibarra, M; Villalobos-Molina, R	1
Ishida, Y; Kawabe, K; Kurimoto, S; Moriyama, N; Nakamura, T; Orikasa, E	1
Jarvis, JE; Reeves, JJ; Sheehan, MJ; Strong, P	1
Isaka, N; Ito, M; Itoh, H; Konishi, T; Miyahara, M; Nakano, T; Shiraishi, T	1
Becker, AJ; Forssmann, WG; Jonas, U; Meyer, M; Schulz-Knappe, P; Stief, CG; Taher, A; Truss, M; Uckert, S	1
Chern, JW; Lee, YM; Peng, IH; Sheu, JR; Yen, MH	1
Chalmers, DH; Kenny, BA; Miller, AM; Naylor, AM; O'Connell, J; Williamson, IJ	1
Bsharat, N; Hoffmann, U; Jira, T	1
Hollenberg, MD; Zheng, XL	1
Hollenberg, MD; Renaux, B; Zheng, XL	1
Adachi, H; Ishihara, H; Kabasawa, Y; Kodama, K; Matsukura, M; Miyazaki, K; Takase, Y; Watanabe, N	1
De Groat, WC; Yoshiyama, M	1
Erol, K; Ertan, M; Kiliç, FS; Saraç, S; Yarim, M	2
Antoine, MH; Becker, B; Damas, J; de Tullio, P; Delarge, J; Dupont, L; Fontaine, J; Lebrun, P; Ouedraogo, R; Pirotte, B; Rigo, B; Somers, F	1
Hamann, M; Richter, A	1
Chen, CF; Chiou, WF	1
Bolzano, K	1
Ishihara, Y; Kitamura, S; Kudoh, S; Sasaki, K; Yotsumoto, H	1
Gogerty, JH; Hardtmann, GE; Iorio, LC; Koletar, G; Pfister, OR	1
Diamantis, W; Edelson, J; Gordon, R; Ludwig, BJ; Sofia, RD	1
Herzig, DJ; Schwender, CF; Sunday, BR	1
Inoue, I; Ishida, R; Ochiai, T; Oine, T; Tani, J; Yamada, Y	1
Andersson, KE; Mikkelsen, E; Pedersen, OL	1
Jauernig, RA; Moulds, RF; Shaw, J	1
Yanagi, Y	1
Doggrell, SA; Paton, DM	1
Chen, CF; Chiou, WF; Chou, CJ; Shum, AY	1
Rao, AR; Reddy, VM	1
Abiko, Y; Ichihara, K; Nasa, Y; Yoshida, R	1
Hattori, K; Kobayashi, Y; Shimoura, K; Shinozuka, K	1
Hayashi, Y; Ikeda, K; Ohnishi, H; Watanabe, K	2
Ebisawa, H; Eguchi, Y; Ishikawa, M; Sasaki, F; Sugimoto, A	1
Hosono, M; Taira, N	1
Buschauer, A; Büyüktimkin, S; Schunack, W	1
Koga, T; Sakai, K; Shiraki, Y	1
Aono, J; Ishizuka, N; Nabata, H; Sakai, K	1
Flores, F; Follmer, C; Ishida, Y; Satake, N; Shibata, S; Suh, TK; Ueda, S	1
Crowley, HJ; Levitan, P; Lind, J; O'Donnell, M; Tilley, JW; Tobias, LD; Welton, AF	1
Itoh, T; Kimoto, Y; Nozaki, M	1
Aono, J; Sakai, K	1
Chen, WZ; Ding, GS; Li, HQ	1
Horii, D; Ishibashi, A	1
Gulati, OD; Gupta, AK; Makol, R; Raghunath, PR; Shah, DS	1
Parratt, JR; Winslow, E	2
Bhargava, KP; Dua, PR; Kohli, RP; Kumar, R	1
Kowa, Y; Ochiai, T; Okumura, K	1
Nott, MW; Winslow, E	2
Bowman, H; Dienel, B; Helt, A; Jen, T; Loev, B; Petta, J	1
Chatterjee, BK; Dey, PK	1

Trials

1 trial(s) available for quinazolines and Muscle Contraction

Article	Year
The long-term effect of alfuzosin in patients with lower urinary tract symptoms suggestive of benign prostate hyperplasia: evaluation of voiding and storage function with respect to bladder outlet obstruction grade and contractility. Urology, 2011, Volume: 77, Issue:5 Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Aged, 80 and over; Humans; Male; Middle Aged; Muscle Contraction; Prospective Studies; Prostatic Hyperplasia; Prostatism; Quinazolines; Time Factors; Urinary Bladder Neck Obstruction	2011

Article

Year

The long-term effect of alfuzosin in patients with lower urinary tract symptoms suggestive of benign prostate hyperplasia: evaluation of voiding and storage function with respect to bladder outlet obstruction grade and contractility.

Urology, 2011, Volume: 77, Issue:5

Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Aged, 80 and over; Humans; Male; Middle Aged; Muscle Contraction; Prospective Studies; Prostatic Hyperplasia; Prostatism; Quinazolines; Time Factors; Urinary Bladder Neck Obstruction

2011

Other Studies

93 other study(ies) available for quinazolines and Muscle Contraction

Article	Year
Onvansertib, a polo-like kinase 1 inhibitor, inhibits prostate stromal cell growth and prostate smooth muscle contraction, which is additive to inhibition by α European journal of pharmacology, 2020, Apr-15, Volume: 873 Topics: Adrenergic alpha-2 Receptor Antagonists; Cell Cycle Proteins; Cell Proliferation; Cell Survival; Cells, Cultured; Drug Synergism; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Piperazines; Polo-Like Kinase 1; Prostate; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pyrazoles; Quinazolines; Stromal Cells; Tumor Stem Cell Assay	2020
Both α Pharmacological reports : PR, 2021, Volume: 73, Issue:1 Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Animals; Dose-Response Relationship, Drug; Male; Muscle Contraction; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Quinazolines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Spleen; Thymine; Yohimbine	2021
Effect of Evodiamine on Rat Colonic Hypermotility Induced by Water Avoidance Stress and the Underlying Mechanism. Drug design, development and therapy, 2021, Volume: 15 Topics: Animals; Avoidance Learning; Colon; Dose-Response Relationship, Drug; Gastrointestinal Motility; Male; Molecular Structure; Muscle Contraction; Quinazolines; Rats; Rats, Wistar; Stress, Psychological; Structure-Activity Relationship	2021
Characteristics of evodiamine-exerted stimulatory effects on rat jejunal contractility. Natural product research, 2015, Volume: 29, Issue:4 Topics: Animals; Calcium; Calcium Channel Blockers; Gastrointestinal Motility; Jejunum; Molecular Structure; Muscle Contraction; Myosins; Nifedipine; Phosphorylation; Quinazolines; Rats; Tetrodotoxin	2015
Smooth muscle contraction and growth of stromal cells in the human prostate are both inhibited by the Src family kinase inhibitors, AZM475271 and PP2. British journal of pharmacology, 2016, Volume: 173, Issue:23 Topics: Blotting, Western; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Prostate; Prostatic Hyperplasia; Pyrimidines; Quinazolines; Real-Time Polymerase Chain Reaction; src-Family Kinases; Stromal Cells	2016
Alfuzosin attenuates erectile dysfunction in rats with partial bladder outlet obstruction. BJU international, 2008, Volume: 102, Issue:11 Topics: Adrenergic alpha-Antagonists; Animals; Blotting, Western; Erectile Dysfunction; Immunohistochemistry; Male; Muscle Contraction; Muscle Relaxation; Nitric Oxide Synthase; Penile Erection; Penis; Quinazolines; Rats; Rats, Sprague-Dawley; Urinary Bladder Neck Obstruction	2008
Receptor tyrosine kinases as mediators of injury-induced bradykinin B1 receptor expression in rabbit aortic smooth muscle. European journal of pharmacology, 2009, Mar-15, Volume: 606, Issue:1-3 Topics: Animals; Aorta; Bradykinin; Epidermal Growth Factor; ErbB Receptors; Humans; In Vitro Techniques; Interleukin-1; Muscle Contraction; Myocytes, Smooth Muscle; Phosphorylation; Protein Kinase Inhibitors; Quinazolines; Rabbits; Receptor Protein-Tyrosine Kinases; Receptor, Bradykinin B1; Tyrphostins; Up-Regulation	2009
Effects of four different alpha(1)-adrenoceptor antagonists on alpha-adrenoceptor agonist-induced contractions in isolated mouse and hamster ureters. Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 2009, Volume: 45, Issue:4 Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cricetinae; Doxazosin; Indoles; Male; Mesocricetus; Mice; Mice, Inbred ICR; Muscle Contraction; Norepinephrine; Prazosin; Quinazolines; Ureter	2009
Imatinib mesylate (Gleevec) as protein-tyrosine kinase inhibitor elicits smooth muscle relaxation in isolated human prostatic tissue. Urology, 2011, Volume: 78, Issue:4 Topics: Adrenergic alpha-Antagonists; Aged; Benzamides; Humans; Hyperplasia; Imatinib Mesylate; Male; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Piperazines; Prostate; Prostatic Diseases; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Quinazolines	2011
Tyrosine kinases regulate intracellular calcium during alpha(2)-adrenergic contraction in rat aorta. American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:4 Topics: Adrenergic alpha-Agonists; Animals; Aorta; Brimonidine Tartrate; Calcium; Enzyme Inhibitors; Flavonoids; Hypertension; Male; Mitogen-Activated Protein Kinases; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidines; Quinazolines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Tyrphostins	2002
Endothelial responses of the aorta from adrenomedullin transgenic mice and knockout mice. Hypertension research : official journal of the Japanese Society of Hypertension, 2003, Volume: 26 Suppl Topics: Acetylcholine; Adrenomedullin; Animals; Aorta, Thoracic; Calcitonin Gene-Related Peptide; Endothelium, Vascular; Enzyme Inhibitors; Male; Mice; Mice, Knockout; Mice, Transgenic; Miotics; Muscle Contraction; NG-Nitroarginine Methyl Ester; Peptide Fragments; Peptides; Phosphodiesterase Inhibitors; Piperidines; Quinazolines; Vasoconstriction; Vasodilator Agents	2003
A comparison of the effects of tamsulosin and alfuzosin on neurally evoked increases in bladder neck and seminal vesicle pressure in rats. BJU international, 2004, Volume: 93, Issue:4 Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Ejaculation; Evoked Potentials; Male; Muscle Contraction; Pressure; Quinazolines; Rats; Rats, Wistar; Seminal Vesicles; Sulfonamides; Tamsulosin; Urinary Bladder	2004
Highly selective iNOS inhibition and sphincter of Oddi motility in the Australian possum. Acta physiologica Scandinavica, 2004, Volume: 181, Issue:3 Topics: Animals; Blood Pressure; Culture Techniques; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gastrointestinal Motility; Lysine; Muscle Contraction; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Opossums; Pancreas; Quinazolines; Regional Blood Flow; Sphincter of Oddi	2004
Evaluation of tamsulosin and alfuzosin activity in the rat vas deferens: relevance to ejaculation delays. The Journal of pharmacology and experimental therapeutics, 2005, Volume: 312, Issue:2 Topics: Adrenergic alpha-Antagonists; Animals; Dose-Response Relationship, Drug; Ejaculation; Electric Stimulation; Epididymis; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Quinazolines; Rats; Rats, Sprague-Dawley; Sulfonamides; Tamsulosin; Vas Deferens; Vasoconstrictor Agents	2005
(+)-Cyclazosin, a selective alpha1B-adrenoceptor antagonist: functional evaluation in rat and rabbit tissues. European journal of pharmacology, 2005, Oct-17, Volume: 522, Issue:1-3 Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Binding, Competitive; Clonidine; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Methoxamine; Molecular Structure; Muscle Contraction; Norepinephrine; Quinazolines; Quinoxalines; Rabbits; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Vas Deferens; Vasoconstriction	2005
Deficient E-cadherin adhesion in C57BL/6J-Min/+ mice is associated with increased tyrosine kinase activity and RhoA-dependent actomyosin contractility. Experimental cell research, 2006, Feb-15, Volume: 312, Issue:4 Topics: Actin Depolymerizing Factors; Actomyosin; Adenomatous Polyposis Coli Protein; Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; beta Catenin; Cadherins; Calcium; Cardiac Myosins; Celecoxib; Cell Adhesion; Egtazic Acid; Enterocytes; ErbB Receptors; Focal Adhesion Kinase 2; GTP-Binding Protein alpha Subunits, G12-G13; Intestinal Mucosa; Intestine, Small; Lysophospholipids; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Microscopy, Electron, Transmission; Mitogen-Activated Protein Kinase 1; Muscle Contraction; Muscle Relaxants, Central; Myosin Light Chains; Phosphorylation; Protein Binding; Protein-Tyrosine Kinases; Pyrazoles; Pyridines; Quinazolines; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Sulfonamides; Tyrphostins; Up-Regulation	2006
Inhibitory responses to exogenous adenosine in murine proximal and distal colon. British journal of pharmacology, 2006, Volume: 148, Issue:7 Topics: Adenosine; Animals; Colon; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Purinergic P1 Receptor Antagonists; Quinazolines; Receptors, Purinergic P1; Signal Transduction; Theobromine; Triazoles; Xanthines	2006
Human epididymal and prostatic tracts of vas deferens: different contraction response to noradrenaline stimulation in isolated organ bath assay. European journal of pharmacology, 2007, Dec-22, Volume: 577, Issue:1-3 Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Aged; Dose-Response Relationship, Drug; Doxazosin; Epididymis; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Norepinephrine; Organ Specificity; Prazosin; Prostate; Quinazolines; Stimulation, Chemical; Vas Deferens	2007
Interleukin 13 increases contractility of murine tracheal smooth muscle by a phosphoinositide 3-kinase p110delta-dependent mechanism. Molecular pharmacology, 2008, Volume: 73, Issue:5 Topics: Adenine; Animals; Bronchial Hyperreactivity; Carbachol; Chromones; Class I Phosphatidylinositol 3-Kinases; In Vitro Techniques; Interleukin-13; Isoenzymes; Lung; Mice; Mice, Mutant Strains; Morpholines; Muscle Contraction; Muscle, Smooth; Mutant Proteins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Potassium Chloride; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinazolines; Tissue Extracts; Trachea	2008
The cardiopulmonary effects of a quinazoline (MJ 1988): cardiac stimulant, pulmonary vasodilator and bronchodilator. The Journal of pharmacology and experimental therapeutics, 1967, Volume: 155, Issue:1 Topics: Aminophylline; Animals; Arrhythmias, Cardiac; Blood Flow Velocity; Bronchi; Dogs; Heart; Muscle Contraction; Pulmonary Circulation; Quinazolines; Theophylline	1967
Inotropic augmentation of myocardial oxygen consumption. The American journal of physiology, 1967, Volume: 212, Issue:5 Topics: Animals; Coronary Vessels; Dogs; Female; Heart; Heart Rate; Male; Muscle Contraction; Myocardium; Norepinephrine; Oxygen Consumption; Quinazolines; Regional Blood Flow; Strophanthins	1967
Effects of compound MJ-1988 on myocardial contractility, oxygen consumption, coronary blood flow and vascular resistance. British journal of pharmacology and chemotherapy, 1967, Volume: 31, Issue:1 Topics: Animals; Blood Flow Velocity; Dogs; Muscle Contraction; Myocardium; Oxygen Consumption; Phenoxybenzamine; Quinazolines; Vascular Resistance	1967
The effect of prazosin on the guinea-pig ileum. British journal of pharmacology, 1980, Volume: 70, Issue:3 Topics: Adrenergic alpha-Antagonists; Animals; Electric Stimulation; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phentolamine; Prazosin; Quinazolines; Yohimbine	1980
Effects of alpha blockers on blood pressure and on the Ca-contracture of cat aortic strips. Japanese journal of pharmacology, 1980, Volume: 30, Issue:4 Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Blood Pressure; Calcium; Cats; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Phentolamine; Quinazolines; Regional Blood Flow	1980
The alpha-adrenergic blocking effect of prazosin on the human prostate. Urological research, 1981, Volume: 9, Issue:1 Topics: Adenoma; Adrenergic alpha-Antagonists; Humans; Male; Muscle Contraction; Prazosin; Prostate; Prostatic Neoplasms; Quinazolines; Receptors, Adrenergic; Receptors, Adrenergic, alpha	1981
Comparison of pre- and postsynaptic alpha-adrenoceptor blocking effects of E-643 in the isolated vas deferens of the rat. Japanese journal of pharmacology, 1981, Volume: 31, Issue:3 Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Contraction; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vas Deferens	1981
(-)-Amidephrine, a selective agonist for alpha 1-adrenoceptors. European journal of pharmacology, 1983, Aug-05, Volume: 91, Issue:4 Topics: Adrenergic alpha-Agonists; Animals; Electric Stimulation; Ethanolamines; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenylephrine; Prazosin; Quinazolines; Rats; Vas Deferens	1983
Effects of a new alpha 1-adrenoceptor blocking agent, 3-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-(1H,3H)-quinazoline-2, 4-dione monohydrochloride (SGB1534), on electrical and mechanical properties of guinea-pig mesenteric artery. Japanese journal of pharmacology, 1984, Volume: 35, Issue:1 Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Electric Stimulation; Female; Guinea Pigs; Histamine; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Quinazolines; Serotonin; Synaptic Transmission	1984
[Studies on the drug-receptor kinetics of dimethylcurine methylchloride]. Yao xue xue bao = Acta pharmaceutica Sinica, 1984, Volume: 19, Issue:4 Topics: Acetylcholine; Animals; Bufonidae; In Vitro Techniques; Kinetics; Muscle Contraction; Neuromuscular Nondepolarizing Agents; Quinazolines; Receptors, Nicotinic; Tubocurarine	1984
Prazosin protects vascular alpha-adrenoceptors against irreversible blockade by phenoxybenzamine. Archives internationales de pharmacodynamie et de therapie, 1980, Volume: 244, Issue:1 Topics: Animals; Muscle Contraction; Muscle, Smooth; Phenoxybenzamine; Phentolamine; Potassium Chloride; Prazosin; Quinazolines; Rabbits; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha	1980
Prazosin selectively inhibits the responses to field stimulation in the rat vas deferens. European journal of pharmacology, 1981, May-22, Volume: 71, Issue:4 Topics: Acetylcholine; Animals; Atropine; Electric Stimulation; Hexamethonium Compounds; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Prazosin; Quinazolines; Rats; Receptors, Adrenergic, alpha; Vas Deferens	1981
The effects of prazosin, phentolamine and phenoxybenzamine on inhibitory alpha-adrenoceptors in the guniea-pig isolated ileum. British journal of pharmacology, 1982, Volume: 76, Issue:2 Topics: Acetylcholine; Animals; Drug Interactions; Electric Stimulation; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenoxybenzamine; Phentolamine; Prazosin; Quinazolines; Receptors, Adrenergic; Receptors, Adrenergic, alpha	1982
Antagonists of slow-reacting substance of anaphylaxis. 1. Pyrido[2,1-b]quinazolinecarboxylic acid derivatives. Journal of medicinal chemistry, 1983, Volume: 26, Issue:11 Topics: Animals; Biological Assay; Guinea Pigs; Ileum; Indicators and Reagents; Leukotriene E4; Muscle Contraction; Quinazolines; Rats; SRS-A; Structure-Activity Relationship	1983
Dissociation of presynaptic alpha 2-adrenoceptors following prazosin administration: presynaptic effect of prazosin. European journal of pharmacology, 1983, Nov-25, Volume: 95, Issue:3-4 Topics: Animals; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Prazosin; Propranolol; Quinazolines; Rats; Receptors, Adrenergic, alpha; Synapses; Vas Deferens; Xylazine; Yohimbine	1983
Modification by yohimbine and prazosin of the mechanical response of isolated dog mesenteric, renal and coronary arteries to transmural stimulation and norepinephrine. European journal of pharmacology, 1984, Feb-10, Volume: 98, Issue:1 Topics: Animals; Coronary Vessels; Dogs; Electric Stimulation; Female; Male; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Quinazolines; Renal Artery; Yohimbine	1984
The effect of Ro 21-7634 on the antigen-induced production of bronchoconstrictive arachidonic acid metabolites in the guinea pig lung. Agents and actions, 1982, Volume: 12, Issue:4 Topics: Airway Resistance; Anaphylaxis; Animals; Arachidonic Acid; Arachidonic Acids; Ascitic Fluid; Calcimycin; Guinea Pigs; Lung; Male; Muscle Contraction; Muscle, Smooth; Quinazolines; SRS-A; Thromboxanes	1982
Synthesis and antiarrhythmic and parasympatholytic properties of substituted phenols. 1. Heteroarylamine derivatives. Journal of medicinal chemistry, 1983, Volume: 26, Issue:6 Topics: Animals; Anti-Arrhythmia Agents; Dogs; Guinea Pigs; Ileum; Male; Muscle Contraction; Parasympatholytics; Quinazolines	1983
[Excellence of quipazine in the characterization of serotoninergic receptors and mechanisms]. Gaceta medica de Mexico, 1982, Volume: 118, Issue:4 Topics: Animals; Behavior, Animal; Cats; Chemical Phenomena; Chemistry; Guinea Pigs; Humans; Muscle Contraction; Quinazolines; Quinolines; Quipazine; Rabbits; Rats; Receptors, Serotonin; Serotonin; Structure-Activity Relationship	1982
Analysis of the antagonism by prazosin of noradrenaline and phenylephrine induced contractions of the rat anococcygeus muscle. Journal of autonomic pharmacology, 1982, Volume: 2, Issue:4 Topics: Anal Canal; Animals; Coccyx; Dose-Response Relationship, Drug; Male; Muscle Contraction; Muscles; Norepinephrine; Phenylephrine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains	1982
Effect of BL-5111-A, prazosin and phentolamine on responses of canine cutaneous veins to adrenergic activation. Archives internationales de pharmacodynamie et de therapie, 1980, Volume: 244, Issue:2 Topics: Animals; Cocaine; Dogs; Dose-Response Relationship, Drug; Drug Antagonism; Estradiol; Estrogen Antagonists; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Prazosin; Propranolol; Quinazolines; Saphenous Vein; Sympathomimetics	1980
The 5-HT2 receptor antagonist, pelanserin, inhibits alpha 1-adrenoceptor-mediated vasoconstriction in vitro. European journal of pharmacology, 1995, Apr-24, Volume: 277, Issue:2-3 Topics: Animals; Aorta; Blood Pressure; Carotid Arteries; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Mesenteric Arteries; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Quinazolines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha-1; Serotonin Antagonists; Tail; Vasoconstriction	1995
Effect of bunazosin, alpha 1-adrenoceptor blocker, on multidirectional contractile response and localization of bunazosin binding sites in human hypertrophied prostate. General pharmacology, 1995, Volume: 26, Issue:5 Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Autoradiography; Binding Sites; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Norepinephrine; Prostate; Prostatic Hyperplasia; Quinazolines; Receptors, Adrenergic, alpha-1	1995
Further investigations into adenosine A1 receptor-mediated contraction in rat colonic muscularis mucosae and its augmentation by certain alkylxanthine antagonists. British journal of pharmacology, 1995, Volume: 114, Issue:5 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colon; Cyclooxygenase Inhibitors; In Vitro Techniques; Indomethacin; Intestinal Mucosa; Muscle Contraction; Muscle, Smooth; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Theophylline; Triazoles; Vasodilator Agents; Xanthines	1995
Isoenzymes of cyclic nucleotide phosphodiesterase in the human aorta: characterization and the effects of E4021. European journal of pharmacology, 1995, Sep-15, Volume: 284, Issue:1-2 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Aorta; Calcium-Calmodulin-Dependent Protein Kinases; Cytosol; Dinoprost; Humans; In Vitro Techniques; Isoenzymes; Kidney; Kinetics; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Piperidines; Quinazolines; Subcellular Fractions; Vasodilator Agents	1995
Phosphodiesterase isoenzymes in human ureteral smooth muscle: identification, characterization, and functional effects of various phosphodiesterase inhibitors in vitro. Urologia internationalis, 1995, Volume: 55, Issue:4 Topics: Chromatography, Ion Exchange; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Humans; Hydrolysis; In Vitro Techniques; Isoenzymes; Muscle Contraction; Muscle, Smooth; Papaverine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Purinones; Pyrrolidinones; Quinazolines; Rolipram; Ureter	1995
Pharmacological activity of DC-015, a novel potent and selective alpha 1-adrenoceptor antagonist. The Journal of pharmacy and pharmacology, 1996, Volume: 48, Issue:1 Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Binding, Competitive; Blood Pressure; Cyclic AMP; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hypertension; Injections, Intravenous; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Phosphatidylinositols; Prazosin; Quinazolines; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Serotonin Antagonists; Vasoconstriction	1996
Evaluation of the pharmacological selectivity profile of alpha 1 adrenoceptor antagonists at prostatic alpha 1 adrenoceptors: binding, functional and in vivo studies. British journal of pharmacology, 1996, Volume: 118, Issue:4 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Doxazosin; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Pressure; Prostate; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Sulfonamides; Tamsulosin	1996
Effects of quinazoline (3H, 1H)-4-one-2-thiones with axial and central chirality on the contractile response of smooth muscle. Die Pharmazie, 1996, Volume: 51, Issue:9 Topics: Animals; Coronary Vessels; Female; Ileum; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Quinazolines; Rats; Swine; Uterine Contraction	1996
Tyrosine kinase inhibitor-sensitive contractile action of ethanol in gastric smooth muscle: comparison with the action of epidermal growth factor. Proceedings of the Association of American Physicians, 1997, Volume: 109, Issue:1 Topics: 1-Propanol; Animals; Calcium; Catechols; Cyclohexanones; Enzyme Inhibitors; Epidermal Growth Factor; Ethanol; Fomepizole; Genistein; Guinea Pigs; Humans; In Vitro Techniques; Indoles; Indomethacin; Isoflavones; Male; Maleimides; Methanol; Muscle Contraction; Muscle, Smooth; Nitriles; Protein-Tyrosine Kinases; Pyrazoles; Quinazolines; Signal Transduction; Stomach; Tyrphostins	1997
Parallel contractile signal transduction pathways activated by receptors for thrombin and epidermal growth factor-urogastrone in guinea pig gastric smooth muscle: blockade by inhibitors of mitogen-activated protein kinase-kinase and phosphatidyl inositol The Journal of pharmacology and experimental therapeutics, 1998, Volume: 285, Issue:1 Topics: Animals; Arachidonic Acid; Calcium; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Guinea Pigs; Lipoprotein Lipase; Male; Mitogen-Activated Protein Kinase Kinases; Muscle Contraction; Muscle, Smooth, Vascular; Phosphatidylinositols; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Quinazolines; Receptors, Thrombin; Signal Transduction	1998
4-Benzylamino-1-chloro-6-substituted phthalazines: synthesis and inhibitory activity toward phosphodiesterase 5. Journal of medicinal chemistry, 1998, Aug-27, Volume: 41, Issue:18 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Platelets; Coronary Vessels; Cyclic Nucleotide Phosphodiesterases, Type 5; Dinoprost; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Phthalazines; Piperidines; Quinazolines; Swine; Vasodilator Agents	1998
Role of spinal alpha1-adrenoceptor subtypes in the bladder reflex in anesthetized rats. American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 280, Issue:5 Topics: Anesthesia, General; Animals; Brain Stem; Efferent Pathways; Female; Injections, Spinal; Locus Coeruleus; Models, Neurological; Muscle Contraction; Piperazines; Pressure; Quinazolines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Reflex; Thymine; Urethane; Urinary Bladder	2001
4-aryl-6,6-dimethyl-1,2,3,4,5,6,7,8-octahydroquinazoline-2,5-diones: synthesis, chromatographic resolution and pharmacological activity. Die Pharmazie, 2001, Volume: 56, Issue:4 Topics: Animals; Calcium Channel Blockers; Cardiotonic Agents; Cardiovascular Agents; Dimethyl Sulfoxide; Female; Heart Rate; Ileum; In Vitro Techniques; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Quinazolines; Rats; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Stereoisomerism	2001
Original 2-alkylamino-6-halogenoquinazolin-4(3H)-ones and K(ATP) channel activity. Journal of medicinal chemistry, 2001, Aug-02, Volume: 44, Issue:16 Topics: Adenosine Triphosphate; Animals; Aorta; Calcium; Crystallography, X-Ray; Female; Glyburide; Guinea Pigs; Ileum; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Muscle Contraction; Muscle, Smooth; Potassium Channels; Potassium Chloride; Quinazolines; Rats; Rats, Wistar; Rubidium; Structure-Activity Relationship; Uterine Contraction; Uterus	2001
Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia. British journal of pharmacology, 2001, Volume: 134, Issue:2 Topics: Adenosine; Animals; Caffeine; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Female; Male; Mesocricetus; Muscle Contraction; Mutation; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Theobromine; Theophylline; Triazines; Triazoles; Xanthines	2001
Synthesis, enantioseparation and pharmacological activity of 4-aryl-7,7-dimethyl-5-oxo-1,2,3,4,5,6,7,8-octahydroquinazoline-2-thiones. Arzneimittel-Forschung, 2002, Volume: 52, Issue:1 Topics: Animals; Calcium Channel Blockers; Carotid Arteries; Chromatography, High Pressure Liquid; Female; In Vitro Techniques; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Molecular Weight; Muscle Contraction; Muscle, Smooth, Vascular; Potassium Chloride; Quinazolines; Rats; Sheep; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Stereoisomerism	2002
Pharmacological profile of evodiamine in isolated rabbit corpus cavernosum. European journal of pharmacology, 2002, Jun-20, Volume: 446, Issue:1-3 Topics: Aging; Animals; Colforsin; Electric Stimulation; In Vitro Techniques; Isometric Contraction; Male; Muscle Contraction; Muscle Relaxation; Nitric Oxide Donors; Nitroprusside; Nucleotides, Cyclic; Penis; Plant Extracts; Potassium; Potassium Channel Blockers; Quinazolines; Rabbits	2002
[A clinical study with prazosin]. Wiener medizinische Wochenschrift (1946), 1978, Volume: 128 Suppl 1 Topics: Adrenergic alpha-Antagonists; Adult; Aged; Benzothiadiazines; Depression; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Muscle Contraction; Muscle Relaxation; Prazosin; Quinazolines; Sexual Behavior; Sodium Chloride Symporter Inhibitors; Urination Disorders	1978
[The potentiating effect of a new alpha-adrenergic blocking agent (E-643) on the action of bronchodilators (author's transl)]. Kokyu to junkan. Respiration & circulation, 1978, Volume: 26, Issue:11 Topics: Adrenergic alpha-Antagonists; Animals; Bronchodilator Agents; Drug Synergism; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Quinazolines; Trachea	1978
Synthesis and biological evaluation of some 10-substituted 2,3-dihydroimidazo[2,1-b]quinazolin-5(10H)-ones, a new class of bronchodilators. Journal of medicinal chemistry, 1975, Volume: 18, Issue:5 Topics: Animals; Bronchodilator Agents; Dogs; Female; Guinea Pigs; Hemodynamics; Histamine; Histamine H1 Antagonists; Imidazoles; In Vitro Techniques; Isoproterenol; Lethal Dose 50; Male; Mice; Muscle Contraction; Muscle, Smooth; Ovalbumin; Passive Cutaneous Anaphylaxis; Quinazolines; Structure-Activity Relationship; Theophylline; Trachea	1975
Pharmacological properties of 2,3-dihydro-9H-isoxazolo[3,2-b]-quinazolin-9-one (W-2429. Part 2: General pharmacological investigation. Arzneimittel-Forschung, 1977, Volume: 27, Issue:4 Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents, Tricyclic; Antitussive Agents; Cats; Diuresis; Dogs; Enzyme Induction; Female; Gastrointestinal Hemorrhage; Gastrointestinal Motility; Guinea Pigs; Hemodynamics; Isoxazoles; Male; Mice; Motor Activity; Muscle Contraction; Muscle, Smooth; Oxazoles; Postural Balance; Prostaglandin-Endoperoxide Synthases; Quinazolines; Rabbits; Rats; Respiration; Sleep; Stomach Ulcer; Time Factors	1977
11-Oxo-11H-pyrido[2,1-b]quinazoline-8-carboxylic acid, an orally active antiallergy agent. Journal of medicinal chemistry, 1979, Volume: 22, Issue:1 Topics: Animals; Guinea Pigs; Histamine Antagonists; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Passive Cutaneous Anaphylaxis; Quinazolines; Rats; Structure-Activity Relationship	1979
Studies on biologically active halogenated compounds. 1. Synthesis and central nervous system depressant activity of 2-(fluoromethyl)-3-aryl-4(3H)-quinazolinone derivatives. Journal of medicinal chemistry, 1979, Volume: 22, Issue:1 Topics: Animals; Anticonvulsants; Central Nervous System Depressants; Electroshock; Lethal Dose 50; Male; Methaqualone; Mice; Muscle Contraction; Postural Balance; Quinazolines; Structure-Activity Relationship	1979
Comparison of the in vitro effects of prazosin, nifedipine, and dihydralazine in isolated human mesenteric and crural vessels. Archives internationales de pharmacodynamie et de therapie, 1979, Volume: 241, Issue:2 Topics: Adolescent; Adult; Aged; Calcium; Dihydralazine; Humans; Hydralazine; In Vitro Techniques; Leg; Mesenteric Arteries; Mesenteric Veins; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Potassium; Prazosin; Pyridines; Quinazolines	1979
The action of prazosin in human vascular preparations. Archives internationales de pharmacodynamie et de therapie, 1978, Volume: 231, Issue:1 Topics: Barium; Blood Vessels; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Nitroprusside; Norepinephrine; Phentolamine; Prazosin; Quinazolines; Serotonin Antagonists	1978
Inhibition of prostaglandin biosynthesis in rat small intestine by SL-573. Biochemical pharmacology, 1978, Mar-01, Volume: 27, Issue:5 Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acids; Borohydrides; Cattle; Depression, Chemical; Dogs; In Vitro Techniques; Indomethacin; Intestine, Small; Male; Mice; Microsomes; Muscle Contraction; Muscle, Smooth; Oxidation-Reduction; Prostaglandins; Quinazolines; Quinazolinones; Rats; Seminal Vesicles	1978
Effects of prazosin and phentolamine on responses to field stimulation and to noradrenaline in vas deferens and anococcygeus muscle of the rat. Archives internationales de pharmacodynamie et de therapie, 1978, Volume: 233, Issue:2 Topics: Animals; Cocaine; Electric Stimulation; In Vitro Techniques; Male; Methoxamine; Muscle Contraction; Muscle, Smooth; Norepinephrine; Nortriptyline; Phentolamine; Prazosin; Quinazolines; Rats; Vas Deferens	1978
The vasorelaxant effect of evodiamine in rat isolated mesenteric arteries: mode of action. European journal of pharmacology, 1992, May-14, Volume: 215, Issue:2-3 Topics: Animals; Calcium; Calcium Channels; Calcium Chloride; Endothelium, Vascular; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Plant Extracts; Potassium Channels; Quinazolines; Rats; Rats, Sprague-Dawley; Tetraethylammonium Compounds; Vasodilator Agents	1992
Synthesis and H1-antihistaminic activity of beta-alkoxyethyl and beta-(N,N-dialkylamino)ethyl-(3-aryl-3,4-dihydro-4-oxoquinazolin- 2-yl)m ethyl ethers. Die Pharmazie, 1992, Volume: 47, Issue:10 Topics: Animals; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Quinazolines	1992
Positive inotropic and negative chronotropic effects of (-)-cis-diltiazem in rat isolated atria. British journal of pharmacology, 1992, Volume: 105, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Atenolol; Calcium; Diltiazem; Endothelium, Vascular; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Potassium Chloride; Quinazolines; Rats; Rats, Inbred Strains; Stereoisomerism; Verapamil	1992
Role of nitric oxide from the endothelium on the neurogenic contractile responses of rabbit pulmonary artery. European journal of pharmacology, 1992, Nov-03, Volume: 222, Issue:1 Topics: Animals; Arginine; Chromatography, High Pressure Liquid; Electric Stimulation; Electrochemistry; Endothelium, Vascular; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Norepinephrine; Pulmonary Artery; Quinazolines; Rabbits; Sympathetic Nervous System; Tetrodotoxin	1992
[Effect of moxisylyte on the lower urinary tracts (1). Effect on the isolated rabbit urethra and bladder]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1991, Volume: 97, Issue:3 Topics: Adrenergic alpha-Antagonists; Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Moxisylyte; Muscle Contraction; Muscle, Smooth; Phenylephrine; Potassium Chloride; Prazosin; Quinazolines; Rabbits; Urethra; Urinary Bladder	1991
[Effect of moxisylyte on the lower urinary tracts (2). Effect on the urethra in anesthetized dogs]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1991, Volume: 97, Issue:3 Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Moxisylyte; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Phentolamine; Phenylephrine; Prazosin; Quinazolines; Urethra; Yohimbine	1991
Studies on hypotensive agents. Synthesis of 1-substituted 3-(2-chlorophenyl)-6-ethoxycarbonyl-5,7-dimethyl-2,4(1H,3H)-quinazoline diones. Chemical & pharmaceutical bulletin, 1991, Volume: 39, Issue:7 Topics: Animals; Antihypertensive Agents; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Quinazolines; Rabbits	1991
Coronary vasodilator versus cardiac effects of MCI-176, a novel quinazolinone calcium antagonist, in the dog heart. Journal of cardiovascular pharmacology, 1987, Volume: 9, Issue:6 Topics: Animals; Blood Flow Velocity; Calcium; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Female; Heart Conduction System; In Vitro Techniques; Male; Muscle Contraction; Papillary Muscles; Quinazolines; Quinazolinones; Sinoatrial Node; Vasodilation	1987
[Quinazolinones. 16. Synthesis and in vitro pharmacology of 2-aryl-1- ([3-(imidazol-4-yl)propyl]-guanidinylalkyl)-2,3-dihydro-4(1H)- quinazolinones]. Archiv der Pharmazie, 1989, Volume: 322, Issue:2 Topics: Animals; Chemical Phenomena; Chemistry; Guanidines; Guinea Pigs; Histamine H1 Antagonists; Histamine H2 Antagonists; Imidazoles; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Quinazolines	1989
Characterization of a novel alpha 1-adrenoceptor antagonist, SGB-1534, in contractile response of isolated canine arterial and venous smooth muscle to exogenous noradrenaline: comparison with prazosin, phentolamine and yohimbine. Japanese journal of pharmacology, 1989, Volume: 50, Issue:2 Topics: Adrenergic alpha-Antagonists; Animals; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Prazosin; Quinazolines; Yohimbine	1989
Mechanism of the hypotensive effect of a novel phenylpiperazine derivative, SGB-1534: antagonism at alpha 1-adrenergic and 5-HT2 receptors. Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 277, Issue:1 Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Antihypertensive Agents; Decerebrate State; Gastric Fundus; Guinea Pigs; In Vitro Techniques; Ketanserin; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Piperidines; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Serotonin Antagonists	1985
Potent alpha-adrenoceptor blocking action of SGB-1534, a new quinazoline antihypertensive agent in vitro experiments. General pharmacology, 1986, Volume: 17, Issue:2 Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Basilar Artery; Cats; Coronary Vessels; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Prazosin; Quinazolines; Rabbits; Vas Deferens	1986
N-(heterocyclic alkyl)pyrido[2,1-b]quinazoline-8-carboxamides as orally active antiallergy agents. Journal of medicinal chemistry, 1987, Volume: 30, Issue:1 Topics: Administration, Oral; Animals; Blood Platelets; Bronchi; Guinea Pigs; Histamine H1 Antagonists; Humans; In Vitro Techniques; Indicators and Reagents; Leukotriene E4; Magnetic Resonance Spectroscopy; Mass Spectrometry; Muscle Contraction; Pyridines; Quinazolines; Spectrophotometry, Infrared; SRS-A; Structure-Activity Relationship; Thromboxane-A Synthase	1987
Actions of the alpha-1 adrenoceptor blocker bunazosin on the norepinephrine-induced contraction of smooth muscles in the rabbit proximal urethra. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:3 Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Calcium; Dose-Response Relationship, Drug; Guanethidine; Microelectrodes; Muscle Contraction; Muscle, Smooth; Norepinephrine; Potassium; Propranolol; Quinazolines; Rabbits; Urethra	1987
Investigations into the mechanism of the antihypertensive effect of SGB-1534, a novel alpha 1-adrenoceptor antagonist, in rats. Japanese journal of pharmacology, 1988, Volume: 48, Issue:2 Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Clonidine; Heart Rate; In Vitro Techniques; Male; Muscle Contraction; Phenylephrine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine	1988
[Antagonistic effects of changrolin on the contraction of rabbit aortic rings evoked by norepinephrine, potassium and calcium]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1985, Volume: 6, Issue:2 Topics: Animals; Anti-Arrhythmia Agents; Aorta, Thoracic; Calcium Chloride; Female; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium Chloride; Quinazolines; Rabbits	1985
Effect of MCI-176, a new calcium antagonist, on the calcium induced contraction of isolated porcine coronary arteries. Japanese journal of pharmacology, 1987, Volume: 43, Issue:2 Topics: Animals; Calcium Channel Blockers; Calcium Chloride; Coronary Vessels; Diltiazem; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Quinazolines; Quinazolinones; Swine	1987
Neuromuscular blocking action of 2-(2-(3-pyridyl) vinyl)-3-0-tolyl-3, 4-dihydroquinazoline-4-one (SRC 909). Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 209, Issue:2 Topics: Abdominal Muscles; Acetylcholine; Animals; Anura; Atropine; Calcium; Carbachol; Cats; Choline; Cold Temperature; Dose-Response Relationship, Drug; Female; Gallamine Triethiodide; Glycols; In Vitro Techniques; Leg; Male; Methysergide; Morphine; Muscle Contraction; Muscles; Neuromuscular Blocking Agents; Pentolinium Tartrate; Phrenic Nerve; Physostigmine; Potassium Chloride; Pyridines; Quinazolines; Quinazolinones; Rats; Sciatic Nerve; Tubocurarine; Vinyl Compounds	1974
Actions of quazodine (MJ1988) on smooth muscle. British journal of pharmacology, 1971, Volume: 43, Issue:3 Topics: Animals; Aorta; Cats; Depression, Chemical; Duodenum; Electric Stimulation; Female; Guinea Pigs; Ileum; Imidazoles; Male; Muscle Contraction; Muscle, Smooth; Phosphoric Monoester Hydrolases; Portal Vein; Quinazolines; Rabbits; Rats; Receptors, Adrenergic; Theophylline; Trachea; Uterus; Vas Deferens	1971
Spasmolytic activity of some newer quinazolones. Indian journal of physiology and pharmacology, 1967, Volume: 11, Issue:3 Topics: Acetylcholine; Animals; Atropine; Barium; Chemical Phenomena; Chemistry; Drug Antagonism; Histamine; Histamine H1 Antagonists; Ileum; In Vitro Techniques; Muscle Contraction; Parasympatholytics; Quaternary Ammonium Compounds; Quinazolines; Rabbits; Serotonin	1967
Cardiovascular pharmacology of quazodine (MJ-1988), with particular reference to effects of myocardial blood flow and metabolic heat production. British journal of pharmacology, 1971, Volume: 42, Issue:2 Topics: Adrenergic beta-Antagonists; Amino Alcohols; Animals; Aorta; Arrhythmias, Cardiac; Blood Pressure; Blood Vessels; Cardiac Output; Cats; Coronary Vessels; Depression, Chemical; Dilatation; Electrocardiography; Heart; Heart Rate; Heart Ventricles; Isoproterenol; Liver Circulation; Muscle Contraction; Myocardium; Oxygen Consumption; Quinazolines; Regional Blood Flow; Thermometers; Vascular Resistance	1971
Choleretic activities of 1-morpholinoacetyl-2-methyl-3-phenyl-4-oxo-1, 2, 3, 4-tetrahydro quinazoline hydrochloride (HQ-275). Japanese journal of pharmacology, 1972, Volume: 22, Issue:2 Topics: Alcohols; Ampulla of Vater; Animals; Anti-Inflammatory Agents; Blood Pressure; Carbon Tetrachloride Poisoning; Cholagogues and Choleretics; Cholesterol; Cyclohexanes; Dehydrocholic Acid; Female; Gastrointestinal Motility; Lethal Dose 50; Liver; Male; Mice; Morpholines; Muscle Contraction; Quinazolines; Rats; Respiration	1972
Effects of quazodine (MJ 1988) on contractions of the isolated hemidiaphragm of the rat and the biventer cervicis muscle of the chick. British journal of pharmacology, 1973, Volume: 48, Issue:3 Topics: Acetylcholine; Animals; Calcium; Carbachol; Chickens; Diaphragm; Drug Synergism; Electric Stimulation; In Vitro Techniques; Methyl Ethers; Muscle Contraction; Muscles; Quinazolines; Rats; Theophylline; Tubocurarine	1973
Proceedings: Effects of quazodine on cat fast- and slow-contracting skeletal muscles. British journal of pharmacology, 1974, Volume: 50, Issue:3 Topics: Animals; Cats; Muscle Contraction; Muscles; Quinazolines; Time Factors	1974
Amidines. 2. A new class of antihypertensive agents. 1,2,3,5-Tetrahydroimidazo(2,1-b)quinazolines. Journal of medicinal chemistry, 1972, Volume: 15, Issue:7 Topics: Amidines; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Cats; Depression, Chemical; Dogs; Imidazoles; In Vitro Techniques; Kidney; Magnetic Resonance Spectroscopy; Muscle Contraction; Nictitating Membrane; Quinazolines; Rabbits; Rats; Regional Blood Flow; Spectrum Analysis; Structure-Activity Relationship; Ultraviolet Rays	1972
Effect of glycosine on the higher nervous activity. Die Naturwissenschaften, 1967, Volume: 54, Issue:1 Topics: Animals; Anticonvulsants; Blood Pressure; Cocaine; Depression, Chemical; Heart; Higher Nervous Activity; Mescaline; Mice; Muscle Contraction; Pentylenetetrazole; Quinazolines; Seizures; Strychnine; Thiopental	1967