Page last updated: 2024-08-21

quinazolines and Malaria, Falciparum

quinazolines has been researched along with Malaria, Falciparum in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's6 (66.67)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Athanassopoulos, CM; Baltas, M; Koumpoura, CL; Robert, A1
Arimondo, PB; Bozdech, Z; Claës, A; Dobrescu, I; Dziekan, JM; Halby, L; Hammam, E; Nardella, F; Preiser, P; Scherf, A1
Farrukh, A; Kiesow, MJ; Llinás, M; Ngwa, CJ; Orchard, LM; Pradel, G1
Jain, V; Kikuchi, H; Oshima, Y; Sharma, A; Yogavel, M1
Angulo-Barturen, I; Avery, VM; Caron, J; Chen, P; Delves, MJ; Duffy, S; Ferrer, S; Fuchter, MJ; Gamo, FJ; Jiménez-Díaz, MB; Malmquist, NA; Menard, D; Nosten, F; Renia, L; Ruecker, A; Santos Martínez, M; Sanz, LM; Scherf, A; Sinden, RE; Sundriyal, S; Suwanarusk, R; Witkowski, B; Wittlin, S1
Chen, Q; Deitsch, KW; Heinberg, AR; Ukaegbu, UE; Wele, M; Zhang, X1
Bopp, SE; Clardy, J; Clish, CB; Cortese, JF; Derbyshire, ER; Estiu, G; Galinsky, K; Herman, JD; Keller, TL; Lindquist, S; Lukens, AK; Mazitschek, R; Mota, MM; Patel, V; Pepper, LR; Ribacke, U; Santos, SA; Schimmel, P; Sullivan, WJ; Whitman, M; Wiest, O; Wirth, DF; Zhou, H; Zuzarte-Luis, V1
Brun, R; Chitnumsub, P; Dartois, V; Diagana, TT; Goh, A; Kamchonwongpaisan, S; Keller, TH; Kiara, SM; Lakshminarayana, SB; Ma, NL; Maneeruttanarungroj, C; Nzila, A; Rottmann, M; Taweechai, S; Weaver, M; Wittlin, S; Wong, J; Yeung, BK; Yuthavong, Y; Zou, B1
Mital, A1

Reviews

2 review(s) available for quinazolines and Malaria, Falciparum

ArticleYear
Antimalarial Inhibitors Targeting Epigenetics or Mitochondria in
    Molecules (Basel, Switzerland), 2021, Sep-21, Volume: 26, Issue:18

    Topics: Animals; Antimalarials; Dihydroorotate Dehydrogenase; DNA; Drug Discovery; Drug Resistance; Enzyme Inhibitors; Epigenesis, Genetic; Histone Deacetylases; Humans; Malaria, Falciparum; Methyltransferases; Mitochondria; Oxidoreductases Acting on CH-CH Group Donors; Plasmodium falciparum; Quinazolines; Signal Transduction; Structure-Activity Relationship

2021
Recent advances in antimalarial compounds and their patents.
    Current medicinal chemistry, 2007, Volume: 14, Issue:7

    Topics: Animals; Antimalarials; Artemisinins; Folic Acid Antagonists; Humans; Malaria, Falciparum; Patents as Topic; Plasmodium falciparum; Quinazolines; Quinolines

2007

Other Studies

7 other study(ies) available for quinazolines and Malaria, Falciparum

ArticleYear
    ACS infectious diseases, 2023, 06-09, Volume: 9, Issue:6

    Topics: Animals; Antimalarials; Humans; Life Cycle Stages; Malaria; Malaria, Falciparum; Plasmodium falciparum; Prokaryotic Initiation Factor-3; Quinazolines; Quinolines

2023
The G9a Histone Methyltransferase Inhibitor BIX-01294 Modulates Gene Expression during
    International journal of molecular sciences, 2019, Oct-14, Volume: 20, Issue:20

    Topics: Animals; Anopheles; Antimalarials; Azepines; Gene Expression Regulation, Developmental; Germ Cells; Histone-Lysine N-Methyltransferase; Humans; Malaria, Falciparum; Plasmodium falciparum; Quinazolines

2019
Structural and functional analysis of the anti-malarial drug target prolyl-tRNA synthetase.
    Journal of structural and functional genomics, 2014, Volume: 15, Issue:4

    Topics: Amino Acyl-tRNA Synthetases; Antimalarials; Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; Malaria, Falciparum; Piperidines; Plasmodium falciparum; Protozoan Proteins; Quinazolines

2014
Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:2

    Topics: Animals; Antimalarials; Azepines; Female; Hep G2 Cells; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Humans; Malaria; Malaria, Falciparum; Mice; Mice, SCID; Plasmodium berghei; Plasmodium falciparum; Quinazolines

2015
A Unique Virulence Gene Occupies a Principal Position in Immune Evasion by the Malaria Parasite Plasmodium falciparum.
    PLoS genetics, 2015, Volume: 11, Issue:5

    Topics: Antigenic Variation; Antigens, Protozoan; Azepines; Chloroquine; Gene Expression Regulation; Genetic Loci; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Humans; Hydroxamic Acids; Immune Evasion; Inhibitory Concentration 50; Malaria, Falciparum; Models, Theoretical; Piperazines; Plasmodium falciparum; Promoter Regions, Genetic; Protozoan Proteins; Quinazolines; RNA Polymerase II; Terpenes; Transcriptional Activation; Transcriptome

2015
The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs.
    Science translational medicine, 2015, May-20, Volume: 7, Issue:288

    Topics: Amino Acyl-tRNA Synthetases; Animals; Antimalarials; Computer-Aided Design; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Drug Resistance; Enzyme Inhibitors; Erythrocytes; Liver; Malaria, Falciparum; Mice; Models, Molecular; Molecular Structure; Molecular Targeted Therapy; Piperidines; Plasmodium falciparum; Protozoan Proteins; Quinazolines; Quinazolinones; Structure-Activity Relationship; Time Factors

2015
Preclinical evaluation of the antifolate QN254, 5-chloro- N'6'-(2,5-dimethoxy-benzyl)-quinazoline-2,4,6-triamine, as an antimalarial drug candidate.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:6

    Topics: Administration, Oral; Animals; Antimalarials; Biological Availability; Drug Resistance; Female; Folic Acid Antagonists; Humans; In Vitro Techniques; Malaria; Malaria, Falciparum; Male; Mice; Models, Molecular; Mutation; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Pyrimethamine; Quinazolines; Rats; Rats, Wistar; Tetrahydrofolate Dehydrogenase

2010