quinazolines has been researched along with Leukemia L5178 in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dedhar, S; Freisheim, JH; Goldie, JH; Hynes, JB | 2 |
| Boyle, FT; Jackman, AL; McCloskey, ML; Smith, MN; Stephens, TC; Waterman, SE | 1 |
| Bartlett, CA; Boritzki, TJ; Hillard, JA; Howland, EF; Johnston, AL; Kosa, M; Margosiak, SA; Morse, CA; Shetty, BV; Webber, S | 1 |
| Aherne, GW; Boyle, FT; Brunton, L; Jackman, AL; Jansen, G; Kimbell, R; Smith, MN; Stephens, TC; Wardleworth, JM | 1 |
| Brown, SL; Kim, JH; Kim, SH | 1 |
6 other study(ies) available for quinazolines and Leukemia L5178
| Article | Year |
|---|---|
Inhibition of a methotrexate-insensitive dihydrofolate reductase from L5178Y cells by substituted triazines and quinazolines.
Topics: Animals; Cells, Cultured; Folic Acid Antagonists; Leukemia L5178; Leukemia, Experimental; Methotrexate; Mice; Quinazolines; Triazines | 1983 |
Use of murine L5178Y lymphoma thymidine kinase mutants for in vitro and in vivo antitumour efficacy evaluation of novel thymidylate synthase inhibitors.
Topics: Animals; Antineoplastic Agents; Cell Survival; Drug Screening Assays, Antitumor; Folic Acid; Folic Acid Antagonists; Leukemia L5178; Mice; Mice, Inbred DBA; Mutation; Quinazolines; Structure-Activity Relationship; Thiophenes; Thymidylate Synthase; Tumor Cells, Cultured | 1993 |
AG337, a novel lipophilic thymidylate synthase inhibitor: in vitro and in vivo preclinical studies.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Cell Cycle; Enzyme Inhibitors; Folic Acid Antagonists; Growth Inhibitors; Humans; Leukemia L1210; Leukemia L5178; Mice; Quinazolines; Rats; Solubility; Thymidylate Synthase | 1996 |
Cellular pharmacology and in vivo activity of a new anticancer agent, ZD9331: a water-soluble, nonpolyglutamatable, quinazoline-based inhibitor of thymidylate synthase.
Topics: Animals; Antineoplastic Agents; Biological Transport; Cell Division; Female; Humans; Kinetics; Leucovorin; Leukemia L1210; Leukemia L5178; Methotrexate; Mice; Mice, Inbred DBA; Quinazolines; Thymidylate Synthase; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1997 |
The potentiation of radiation response in human colon carcinoma cells in vitro and murine lymphoma in vivo by AG337 (Thymitaq), a novel thymidylate synthase inhibitor.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Survival; Drug Therapy, Combination; Enzyme Inhibitors; HT29 Cells; Humans; Leukemia L5178; Male; Mice; Mice, Inbred DBA; Quinazolines; Thymidylate Synthase | 1998 |
Further studies on substituted quinazolines and triazines as inhibitors of a methotrexate-insensitive murine dihydrofolate reductase.
Topics: Animals; Cell Line; Chemical Phenomena; Chemistry; Leukemia L5178; Methotrexate; Mice; Quinazolines; Tetrahydrofolate Dehydrogenase; Triazines | 1986 |