Page last updated: 2024-08-21

quinazolines and Kidney Diseases

quinazolines has been researched along with Kidney Diseases in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199012 (40.00)18.7374
1990's4 (13.33)18.2507
2000's5 (16.67)29.6817
2010's7 (23.33)24.3611
2020's2 (6.67)2.80

Authors

AuthorsStudies
Chambers, C; Giani, J; Sawyer, MB1
Jaźwiec, B; Kuliszkiewicz-Janus, M; Kwiatkowski, J; Małecki, R; Rymer, W1
Hao, Z; Liang, C; Sun, Y; Wang, C; Zhang, L; Zhou, J1
Emser, A; Gong, Y; von Eynatten, M; Woerle, HJ1
Bossart, W; Etter, A; Fehr, T; Hässig, A; Müller, N; Roos, M; Schiesser, M; Wüthrich, RP1
Li, JJ; Li, ZW; Mao, XQ; Shi, GF; Wang, F; Wang, L; Wang, Q; Wu, JJ; Zhang, JP; Zou, J1
Bao, W; Cheng, SB; Chin, YE; Liu, N; Qiu, A; Shi, Y; Wang, L; Xiong, C; Xu, L; Yan, H; Yang, T; Zhuang, S1
Chadjichristos, C; Chatziantoniou, C; Dussaule, JC; Flamant, M; François, H; Guerrot, D; Helle, F; Jouzel, C; Placier, S1
Langmuir, P; Martin, P; Molz, KH; Oliver, S; Read, J; Smith, R; Weil, A1
Eguchi, S; Fujigaki, Y; Hishida, A; Suzuki, H; Yamamoto, T1
Bonneterre, J; Culine, S; de Jonge, MJ; de Vries, EG; Droz, J; Glimelius, B; Smith, R; Van Groeningen, C; Verweij, J; Young, J1
Blum, RA; Marbury, TC; Pinquier, JL; Rauch, C1
DATEY, KK; PANDYA, VN1
Chansel, D; Chatziantoniou, C; Dussaule, JC; Flamant, M; François, H; Placier, S; Tharaux, PL1
Edelman, MJ; Hohl, RJ; Hollis, DR; Kindler, HL; Lewis, LD; Lichtman, SM; Marshall, JL; Miller, AA; Murry, DJ; Owzar, K; Ratain, MJ; Villalona-Calero, MA1
Delmez, JA; Harter, HR1
Garcez, DM; Kopstein, J1
Arnold, S; Baughman, RA; Benet, LZ; Chatterjee, K; Lin, ET; Williams, RL1
Gotoh, E; Ishii, M; Minamisawa, K; Minamisawa, M; Shionoiri, H; Sugimoto, K; Takasaki, I; Takizawa, T; Ueda, S1
Chmurzyńska, W; Grzelakowska-Sztabert, B; Manteuffel-Cymborowska, M2
Avery, GS; Brogden, RN; Heel, RC; Speight, TM1
Bailey, RR; Little, PJ; Lynn, KL; Neale, TL1
Bensted, JP; Calvert, AH; Clinton, S; Hughes, LR; Jodrell, DI; Morgan, SE; Newell, DR1
Bishop, JA; Calvert, AH; Grzelakowska-Sztabert, B; Gumbrell, LA; Harland, SJ; Harrap, KR; Jackman, AL; Judson, IR; Newell, DR; Sikora, E1
Alison, DL; Calvert, AH; Harland, SJ; Jackman, AL; Jones, TR; McElwain, TJ; Newell, DR; Robinson, BA; Siddik, ZH; Wiltshaw, E1
Lowenthal, DT; Shear, L1
Craswell, PW; Ezzat, E; Kopstein, J; Moorhead, JF; Varghese, Z1
Carmody, M; Keogh, B; Malone, D; O'Dwyer, WF1

Reviews

2 review(s) available for quinazolines and Kidney Diseases

ArticleYear
Efficacy and safety of linagliptin in type 2 diabetes subjects at high risk for renal and cardiovascular disease: a pooled analysis of six phase III clinical trials.
    Cardiovascular diabetology, 2013, Apr-09, Volume: 12

    Topics: Cardiovascular Diseases; Clinical Trials, Phase III as Topic; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Kidney Diseases; Linagliptin; Purines; Quinazolines; Randomized Controlled Trials as Topic; Risk Factors; Treatment Outcome

2013
Prazosin: a review of its pharmacological properties and therapeutic efficacy in hypertension.
    Drugs, 1977, Volume: 14, Issue:3

    Topics: Animals; Benzothiadiazines; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug Eruptions; Drug Therapy, Combination; Heart Rate; Humans; Hydralazine; Hypertension; Kidney; Kidney Diseases; Kinetics; Methyldopa; Prazosin; Quinazolines; Renin; Sodium Chloride Symporter Inhibitors; Time Factors

1977

Trials

5 trial(s) available for quinazolines and Kidney Diseases

ArticleYear
Effects of impaired renal function on the pharmacokinetics and toxicity of i.v. ZD9331, a novel non-polyglutamated thymidylate synthase inhibitor, in adult patients with solid tumors.
    Anti-cancer drugs, 2002, Volume: 13, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents; Blood Cell Count; Creatinine; Enzyme Inhibitors; Female; Hematologic Diseases; Humans; Injections, Intravenous; Kidney Diseases; Male; Middle Aged; Neoplasms; Quinazolines; Thymidylate Synthase

2002
Pharmacokinetics and safety of a single oral dose of once-daily alfuzosin, 10 mg, in male subjects with mild to severe renal impairment.
    Journal of clinical pharmacology, 2002, Volume: 42, Issue:12

    Topics: Administration, Oral; Adolescent; Adrenergic alpha-Antagonists; Adult; Aged; Area Under Curve; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Humans; Infusions, Intravenous; Injections, Subcutaneous; Kidney; Kidney Diseases; Male; Middle Aged; Quinazolines; Receptors, Adrenergic, alpha-1; Time Factors

2002
Phase I and pharmacokinetic study of erlotinib for solid tumors in patients with hepatic or renal dysfunction: CALGB 60101.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Jul-20, Volume: 25, Issue:21

    Topics: Administration, Oral; Adult; Aged; Dose-Response Relationship, Drug; Drug Administration Schedule; Erlotinib Hydrochloride; Female; Follow-Up Studies; Humans; Kidney Diseases; Kidney Function Tests; Liver Diseases; Liver Function Tests; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Neoplasms; Probability; Quinazolines; Risk Assessment; Survival Analysis; Treatment Outcome

2007
Pharmacokinetics and pharmacodynamics of the alpha 1-adrenergic antagonist bunazosin retard in hypertensives.
    Arzneimittel-Forschung, 1994, Volume: 44, Issue:11

    Topics: Adrenergic alpha-1 Receptor Antagonists; Blood Pressure; Delayed-Action Preparations; Female; Half-Life; Humans; Hypertension; Kidney Diseases; Male; Middle Aged; Pulse; Quinazolines

1994
Prazosin: a review of its pharmacological properties and therapeutic efficacy in hypertension.
    Drugs, 1977, Volume: 14, Issue:3

    Topics: Animals; Benzothiadiazines; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug Eruptions; Drug Therapy, Combination; Heart Rate; Humans; Hydralazine; Hypertension; Kidney; Kidney Diseases; Kinetics; Methyldopa; Prazosin; Quinazolines; Renin; Sodium Chloride Symporter Inhibitors; Time Factors

1977

Other Studies

24 other study(ies) available for quinazolines and Kidney Diseases

ArticleYear
Tolerability of pemetrexed and oxaliplatin in the treatment of stage III colon cancer during raltitrexed shortage.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:2

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Canada; Colonic Neoplasms; Female; Humans; Kidney Diseases; Middle Aged; Oxaliplatin; Pemetrexed; Quinazolines; Thiophenes; Tomography, X-Ray Computed; Treatment Outcome

2021
Treatment of Essential Thrombocythemia with Anagrelide Is Associated with an Increased Risk of Worsened Kidney Function.
    Pharmacology, 2021, Volume: 106, Issue:5-6

    Topics: Aged; Calreticulin; Creatinine; Disease Progression; Female; Humans; Hydroxyurea; Janus Kinase 2; Kidney Diseases; Male; Middle Aged; Mutation; Platelet Aggregation Inhibitors; Quinazolines; Retrospective Studies; Risk Factors; Thrombocythemia, Essential; Treatment Outcome

2021
Rutaecarpine alleviates renal ischemia reperfusion injury in rats by suppressing the JNK/p38 MAPK signaling pathway and interfering with the oxidative stress response.
    Molecular medicine reports, 2017, Volume: 16, Issue:1

    Topics: Animals; Biomarkers; Biopsy; Blood Urea Nitrogen; Cytokines; Disease Models, Animal; Indole Alkaloids; Inflammation Mediators; Kidney Diseases; Kidney Function Tests; Male; MAP Kinase Signaling System; Oxidative Stress; Phosphorylation; Protective Agents; Quinazolines; Rats; Reactive Oxygen Species; Reperfusion Injury; Superoxide Dismutase

2017
Association of BK viremia with human leukocyte antigen mismatches and acute rejection, but not with type of calcineurin inhibitor.
    Transplant infectious disease : an official journal of the Transplantation Society, 2014, Volume: 16, Issue:1

    Topics: Adult; Aged; Allografts; Antibodies, Monoclonal; Azathioprine; Basiliximab; BK Virus; Cohort Studies; Cyclosporine; Female; Glomerular Filtration Rate; Graft Rejection; Histocompatibility; HLA Antigens; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Logistic Models; Male; Middle Aged; Multivariate Analysis; Mycophenolic Acid; Polyomavirus Infections; Proteinuria; Pyrroles; Quinazolines; Recombinant Fusion Proteins; Tacrolimus; Tumor Virus Infections; Viremia

2014
Epidermal growth factor receptor inhibitor ameliorates excessive astrogliosis and improves the regeneration microenvironment and functional recovery in adult rats following spinal cord injury.
    Journal of neuroinflammation, 2014, Apr-05, Volume: 11

    Topics: Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Disease Models, Animal; ErbB Receptors; Exploratory Behavior; Female; Glial Fibrillary Acidic Protein; Gliosis; Kidney Diseases; Phosphorylation; Quinazolines; Rats; Rats, Sprague-Dawley; Recovery of Function; Regeneration; Spinal Cord Injuries

2014
EGF Receptor Inhibition Alleviates Hyperuricemic Nephropathy.
    Journal of the American Society of Nephrology : JASN, 2015, Volume: 26, Issue:11

    Topics: Animals; Chemokines; Cytokines; Disease Progression; ErbB Receptors; Fibroblasts; Fibrosis; Gefitinib; Hyperuricemia; Inflammation; Kidney; Kidney Diseases; Male; Phosphorylation; Quinazolines; Rats; Rats, Sprague-Dawley; Risk Factors; Signal Transduction; Transforming Growth Factor beta; Transforming Growth Factor beta1; Uric Acid

2015
Improvement of renal hemodynamics during hypertension-induced chronic renal disease: role of EGF receptor antagonism.
    American journal of physiology. Renal physiology, 2009, Volume: 297, Issue:1

    Topics: Animals; Arterioles; Blood Pressure; Chronic Disease; Disease Models, Animal; Enzyme Inhibitors; ErbB Receptors; Gefitinib; Hypertension; Kidney; Kidney Diseases; Male; NG-Nitroarginine Methyl Ester; Quinazolines; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Vasoconstriction

2009
Pharmacokinetics of vandetanib in subjects with renal or hepatic impairment.
    Clinical pharmacokinetics, 2010, Volume: 49, Issue:9

    Topics: Adult; Aged; Angiogenesis Inhibitors; Area Under Curve; Female; Humans; Kidney Diseases; Liver Diseases; Male; Middle Aged; Piperidines; Quinazolines

2010
Comparison of ROCK and EGFR activation pathways in the progression of glomerular injuries in AngII-infused rats.
    Renal failure, 2011, Volume: 33, Issue:10

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Disease Progression; ErbB Receptors; Gefitinib; Kidney Diseases; Kidney Glomerulus; Male; Protein Kinase Inhibitors; Quinazolines; Rats; Rats, Wistar; rho-Associated Kinases; Signal Transduction

2011
QUINETHAZONE AS A DIURETIC AGENT.
    Journal of postgraduate medicine, 1963, Volume: 9

    Topics: Blood Protein Disorders; Diuretics; Heart Failure; Humans; Kidney Diseases; Liver Cirrhosis; Quinazolines; Sulfonamides

1963
Prevention of renal vascular and glomerular fibrosis by epidermal growth factor receptor inhibition.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:7

    Topics: Animals; Capillaries; Collagen; Collagen Type I; Creatinine; Endothelin-1; ErbB Receptors; Fibrosis; Gefitinib; Gene Expression Regulation; Genes, Reporter; Glomerulosclerosis, Focal Segmental; Hypertension; Ischemia; Kidney; Kidney Cortex; Kidney Diseases; Kidney Glomerulus; Male; MAP Kinase Signaling System; Mice; Mice, Transgenic; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phosphorylation; Promoter Regions, Genetic; Protein Processing, Post-Translational; Proteinuria; Quinazolines; Rats; Rats, Sprague-Dawley

2004
[Effects of prazosin on the control of arterial pressure in hypertensive patients subjected to dialysis].
    Cardiology, 1980, Volume: 66 Suppl 2

    Topics: Blood Volume; Female; Humans; Hypertension; Kidney Diseases; Male; Middle Aged; Prazosin; Quinazolines; Racial Groups; Renal Dialysis; Renin

1980
[Prazosin in the treatment of arterial hypertension].
    Cardiology, 1980, Volume: 66 Suppl 2

    Topics: Adult; Antihypertensive Agents; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Hypertension, Renal; Kidney Diseases; Male; Middle Aged; Posture; Prazosin; Quinazolines

1980
Altered prazosin pharmacokinetics in congestive heart failure.
    European journal of clinical pharmacology, 1980, Volume: 17, Issue:6

    Topics: Adult; Aged; Female; Heart Failure; Humans; Kidney Diseases; Kinetics; Liver; Male; Metabolic Clearance Rate; Middle Aged; Prazosin; Quinazolines

1980
Polyamines in testosterone-induced hypertrophic and antifolate-induced hyperplastic mouse kidney. Differential effect of alpha-difluoromethylornithine.
    Biochimica et biophysica acta, 1993, Sep-08, Volume: 1182, Issue:2

    Topics: Animals; Eflornithine; Female; Folic Acid; Hyperplasia; Hypertrophy; Kidney; Kidney Diseases; Mice; Organ Size; Ornithine Decarboxylase Inhibitors; Polyamines; Quinazolines; Testosterone

1993
Prazosin in the treatment of patients with hypertension and renal functional impairment.
    The New Zealand medical journal, 1976, Dec-22, Volume: 84, Issue:578

    Topics: Female; Humans; Hypertension; Kidney Diseases; Male; Middle Aged; Prazosin; Quinazolines

1976
Ornithine decarboxylase induction in mouse kidney as indicator of renal damage. Differential nephrotoxic effect of anticancer antifolate drugs.
    Cancer letters, 1991, Volume: 59, Issue:3

    Topics: Animals; Antimetabolites, Antineoplastic; Biomarkers; Enzyme Induction; Female; Folic Acid; Folic Acid Antagonists; Indomethacin; Kidney; Kidney Diseases; Methotrexate; Mice; Organ Size; Ornithine Decarboxylase; Quinazolines

1991
The renal effects of N10-propargyl-5,8-dideazafolic acid (CB3717) and a non-nephrotoxic analogue ICI D1694, in mice.
    British journal of cancer, 1991, Volume: 64, Issue:5

    Topics: Animals; Carbon Radioisotopes; Cisplatin; Creatinine; Female; Folic Acid; Glomerular Filtration Rate; Inulin; Kidney; Kidney Diseases; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Quinazolines; Thiophenes; Thymidylate Synthase; Urea

1991
Recent preclinical and clinical studies with the thymidylate synthase inhibitor N10-propargyl-5,8-dideazafolic acid (CB 3717).
    NCI monographs : a publication of the National Cancer Institute, 1987, Issue:5

    Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Diuresis; Drug Evaluation; Folic Acid; Folic Acid Antagonists; Humans; Hydrogen-Ion Concentration; Kidney Diseases; Middle Aged; Quinazolines; Thymidylate Synthase

1987
A phase I evaluation of the quinazoline antifolate thymidylate synthase inhibitor, N10-propargyl-5,8-dideazafolic acid, CB3717.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:8

    Topics: Acetylglucosaminidase; Acid Phosphatase; Alanine Transaminase; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Folic Acid; Folic Acid Antagonists; Glomerular Filtration Rate; Hematologic Diseases; Hyperbilirubinemia; Kidney Diseases; Leucyl Aminopeptidase; Neoplasms; Quinazolines; Skin Diseases; Thymidylate Synthase

1986
New drugs--No. 12. Metolazone (zaroxolyn).
    Journal of the Irish Medical Association, 1972, Oct-27, Volume: 66, Issue:20

    Topics: Antihypertensive Agents; Diuretics; Dose-Response Relationship, Drug; Drug Evaluation; Edema; Heart Failure; Hypertension; Kidney Diseases; Quinazolines; Sulfonamides

1972
Use of a new diuretic agent (metolazone) in patients with edema and ascites.
    Archives of internal medicine, 1973, Volume: 132, Issue:1

    Topics: Ascites; Blood Urea Nitrogen; Creatinine; Diuretics; Edema; Furosemide; Humans; Injections, Intravenous; Kidney Diseases; Liver Cirrhosis; Natriuresis; Potassium; Protein Binding; Quinazolines; Sodium; Sulfonamides; Time Factors; Urea

1973
Use of metolazone, a new diuretic, in patients with renal disease.
    Nephron, 1974, Volume: 12, Issue:1

    Topics: Administration, Oral; Adult; Antihypertensive Agents; Blood Glucose; Blood Pressure; Creatinine; Diuretics; Edema; Female; Glomerular Filtration Rate; Humans; Hypertension; Injections, Intravenous; Inulin; Kidney Diseases; Liver Function Tests; Male; Middle Aged; Potassium; Quinazolines; Renin; Sodium; Sulfonamides; Uric Acid

1974
Clinical and biochemical evaluation of a new diuretic agent (Metolazone).
    Journal of the Irish Medical Association, 1971, May-27, Volume: 64, Issue:412

    Topics: Adolescent; Adult; Aged; Diuretics; Female; Heart Failure; Humans; Hypertension; Ketones; Kidney Diseases; Kidney Function Tests; Liver Function Tests; Male; Middle Aged; Pulmonary Heart Disease; Quinazolines; Sulfonamides

1971