quinazolines has been researched along with Germinoblastoma in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (15.79) | 18.7374 |
| 1990's | 3 (15.79) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 7 (36.84) | 24.3611 |
| 2020's | 3 (15.79) | 2.80 |
| Authors | Studies |
|---|---|
| Arkenau, HT; Awada, A; Cisternas, G; Cunningham, D; Fruchart, C; Genvresse, I; Granvil, C; Grevel, J; Kneip, C; Köchert, K; Liu, L; Machiels, JP; Morschhauser, F; Peña, CE; Peyrade, F; Reschke, S; Rottey, S; Rule, SAJ; Salles, G; Shen, K; Zhang, J | 1 |
| Anghore, D; Bhatia, R; Chawla, P; Kumar, A; Rawal, RK; Saini, V | 1 |
| Follows, GA; Munoz, J; Nastoupil, LJ | 1 |
| Assouline, SE; Bouabdallah, K; Bron, D; Childs, BH; Cunningham, D; Dreyling, M; Garcia-Vargas, J; Giurescu, M; Gorbatchevsky, I; Hiemeyer, F; Koechert, K; Linton, K; Liu, L; Morschhauser, F; Neves, M; Peña, C; Thieblemont, C; Verhoef, G; Vitolo, U; Zinzani, PL | 1 |
| Bu, W; Chang, G; Chang, S; Dai, B; Hou, J; Hu, L; Kong, Y; Lan, X; Shi, J; Tao, Y; Wang, Y; Wei, Q; Wu, H; Xiao, W; Xie, B; Xie, Y; Yang, G; Yu, D; Zheng, J | 1 |
| Anderson, LW; Chen, A; Collins, JM; Doroshow, JH; Gutierrez, ME; Klecker, RW; Kummar, S; Murgo, AJ | 1 |
| Anbu, S; Guedes da Silva, MF; Koch, B; Kuznetsov, ML; Paul, A; Pombeiro, AJ; Sharma, G | 1 |
| de Castro, J; García-Campelo, R; Isla, D; Provencio, M | 1 |
| Allen, D; Cao, L; Chen, A; Chen, H; Choyke, P; Collins, J; Doroshow, JH; Gutierrez, ME; Horneffer, YR; Juwara, L; Kim, YS; Kummar, S; Melillo, G; Murgo, AJ; Trepel, J; Turkbey, IB; Yu, Y | 1 |
| Bendapudi, PK; Chen, J; Choi, P; Felsher, DW; Horng, G; Hughes, NP; Kawashima, T; Kitamura, T; Koh, S; Lin, HJ; Miller, VA; Paik, D; Schwartz, LH; Tran, PT | 1 |
| Evens, A; Osborne, CK | 1 |
| Diddens, H; Jackson, RC; Niethammer, D | 1 |
| Aherne, GW; Gibson, W; Jackman, AL; Lawrence, N; Smith, MN; Stephens, TC; Walton, MI | 1 |
| Bertucci, D; Goh, BC; Mani, S; Ratain, MJ; Vogelzang, NJ; Vokes, EE | 1 |
| Baek, DJ; Ha, JR; Oh, SW | 1 |
| Aherne, GW; Brunton, L; Crompton, T; Dobinson, D; Hardcastle, A; Jackman, AL; Valenti, M; Ward, E | 1 |
| Donsback, RC; Sirotnak, FM | 1 |
| Gaumont, Y; Greco, WR; Kisliuk, RL; Parsons, JC | 1 |
| Gaumont, Y; Kisliuk, RL; Murthy, BR; Nair, MG; Piper, JR; Sirotnak, FM; Thorndike, J | 1 |
3 review(s) available for quinazolines and Germinoblastoma
| Article | Year |
|---|---|
Copanlisib: Novel PI3K Inhibitor for the Treatment of Lymphoma.
Topics: Antineoplastic Agents; Clinical Trials as Topic; Dose-Response Relationship, Drug; Humans; Lymphoma; Molecular Structure; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pyrimidines; Quinazolines; Structure-Activity Relationship | 2020 |
Copanlisib for the Treatment of Malignant Lymphoma: Clinical Experience and Future Perspectives.
Topics: Humans; Lymphoma; Pyrimidines; Quinazolines | 2021 |
Clinical-molecular factors predicting response and survival for tyrosine-kinase inhibitors.
Topics: Angiogenesis Inhibitors; Biomarkers, Tumor; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Female; Humans; Lung Neoplasms; Lymphoma; Male; Neoplasms; Prognosis; Protein Kinase Inhibitors; Quinazolines; Survival Rate; Treatment Outcome | 2009 |
5 trial(s) available for quinazolines and Germinoblastoma
| Article | Year |
|---|---|
On-Target Pharmacodynamic Activity of the PI3K Inhibitor Copanlisib in Paired Biopsies from Patients with Malignant Lymphoma and Advanced Solid Tumors.
Topics: Biopsy; Cell Line, Tumor; Female; Humans; Lymphoma; Male; Neoplasms; Phosphatidylinositol 3-Kinases; Pyrimidines; Quinazolines | 2020 |
Phase II study of copanlisib, a PI3K inhibitor, in relapsed or refractory, indolent or aggressive lymphoma.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Biomarkers, Tumor; Female; Humans; Lymphoma; Male; Middle Aged; Phosphoinositide-3 Kinase Inhibitors; PTEN Phosphohydrolase; Pyrimidines; Quinazolines; Recurrence; Survival Analysis | 2017 |
Pharmacogenetically driven patient selection for a first-in-human phase I trial of batracylin in patients with advanced solid tumors and lymphomas.
Topics: Adult; Aged; Antineoplastic Agents; Arylamine N-Acetyltransferase; Dose-Response Relationship, Drug; Female; Genotype; Humans; Lymphoma; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Patient Selection; Pharmacogenetics; Quinazolines; Species Specificity; Young Adult | 2013 |
Phase I trial of vandetanib and bevacizumab evaluating the VEGF and EGF signal transduction pathways in adults with solid tumours and lymphomas.
Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Biomarkers, Tumor; Contrast Media; Epidermal Growth Factor; Female; Humans; Lymphoma; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasms; Piperidines; Quinazolines; Signal Transduction; Time Factors; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2011 |
A Phase I study of raltitrexed and paclitaxel given every 3 weeks to patients with solid tumors.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Drug Administration Schedule; Drug Evaluation; Female; Humans; Lymphoma; Male; Middle Aged; Neoplasms; Neutropenia; Paclitaxel; Quinazolines; Thiophenes | 1999 |
11 other study(ies) available for quinazolines and Germinoblastoma
| Article | Year |
|---|---|
PKC inhibition of sotrastaurin has antitumor activity in diffuse large B-cell lymphoma via regulating the expression of MCT-1.
Topics: Animals; Apoptosis; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Gene Silencing; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Oncogene Proteins; Protein Kinase C; Pyrroles; Quinazolines; RNA, Messenger; RNA, Small Interfering; Signal Transduction | 2018 |
Intracellular detection of Cu(2+) and S(2-) ions through a quinazoline functionalized benzimidazole-based new fluorogenic differential chemosensor.
Topics: Benzimidazoles; Biosensing Techniques; Coordination Complexes; Copper; Crystallography, X-Ray; Fluorescent Dyes; Humans; Lymphoma; Quinazolines; Spectrometry, Fluorescence; Sulfur; Tumor Cells, Cultured | 2015 |
Survival and death signals can predict tumor response to therapy after oncogene inactivation.
Topics: Animals; Apoptosis; Blotting, Western; Cell Proliferation; Computer Simulation; Disease-Free Survival; ErbB Receptors; Erlotinib Hydrochloride; Genotype; Humans; Lung Neoplasms; Lymphoma; Mice; Mice, Transgenic; Models, Theoretical; Oncogenes; Polymerase Chain Reaction; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins p21(ras); Quinazolines; Tumor Cells, Cultured | 2011 |
Select interviews from the 2011 San Antonio Breast Cancer Symposium (SABCS) and American Society of Hematology (ASH) Annual Meeting.
Topics: Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Breast Neoplasms; Cyclophosphamide; Dacarbazine; Doxorubicin; Female; Fertility Preservation; Humans; Lapatinib; Lymphoma; Molecular Targeted Therapy; Prednisone; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Outcome; Quinazolines; Receptor, ErbB-2; Rituximab; Trastuzumab; Vinblastine; Vincristine | 2011 |
Patterns of cross-resistance to the antifolate drugs trimetrexate, metoprine, homofolate, and CB3717 in human lymphoma and osteosarcoma cells resistant to methotrexate.
Topics: Antineoplastic Agents; Biological Transport; Burkitt Lymphoma; Cell Line; Drug Resistance; Folic Acid; Folic Acid Antagonists; Humans; Kinetics; Leukemia, Lymphoid; Lymphoma; Methotrexate; Osteosarcoma; Pyrimethamine; Quinazolines; Structure-Activity Relationship; T-Lymphocytes; Tetrahydrofolate Dehydrogenase; Trimetrexate | 1983 |
Preclinical pharmacology of CB30900, a novel dipeptide inhibitor of thymidylate synthase, in mice.
Topics: Animals; Dipeptides; Enzyme Inhibitors; Intestinal Mucosa; Lymphoma; Metabolic Clearance Rate; Mice; Mice, Inbred DBA; Protein Binding; Quinazolines; Thymidylate Synthase; Tissue Distribution | 1996 |
In vivo antitumor efficacy of CW252053, a folate-based thymidylate synthase inhibitor.
Topics: Animals; Antineoplastic Agents; Female; Folic Acid Antagonists; Glycine; Lymphoma; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Quinazolines; Survival Analysis; Thymidylate Synthase; Tumor Cells, Cultured | 2001 |
Pharmacokinetic/pharmacodynamic study of ZD9331, a nonpolyglutamatable inhibitor of thymidylate synthase, in a murine model following two curative administration schedules.
Topics: Animals; Antineoplastic Agents; Deoxyribonucleotides; Disease Models, Animal; Drug Administration Schedule; Enzyme-Linked Immunosorbent Assay; Female; Infusion Pumps; Injections, Intraperitoneal; Injections, Subcutaneous; Lymphoma; Mice; Mice, Inbred DBA; Nucleoside-Phosphate Kinase; Quinazolines; Time Factors; Tissue Distribution | 2001 |
Further evidence for a basis of selective activity and relative responsiveness during antifolate therapy of murine tumors.
Topics: Aminopterin; Animals; Aspartic Acid; Carcinoma, Ehrlich Tumor; Chick Embryo; DNA, Neoplasm; Folic Acid Antagonists; Intestine, Small; Leukemia L1210; Liver; Lymphoma; Methotrexate; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Quinazolines; Sarcoma 180; Tetrahydrofolate Dehydrogenase; Time Factors | 1975 |
Quantitation of folic acid enhancement of antifolate synergism.
Topics: Cell Division; Dose-Response Relationship, Drug; Drug Synergism; Folic Acid; Folic Acid Antagonists; Humans; Lymphoma; Quinazolines; Tetrahydrofolates; Trimetrexate; Tumor Cells, Cultured | 1992 |
Inhibition of glycinamide ribonucleotide formyltransferase and other folate enzymes by homofolate polyglutamates in human lymphoma and murine leukemia cell extracts.
Topics: Acyltransferases; Animals; Folic Acid; Humans; Hydroxymethyl and Formyl Transferases; Kinetics; Leukemia L1210; Lymphoma; Mice; Molecular Conformation; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Phosphoribosylglycinamide Formyltransferase; Pteroylpolyglutamic Acids; Quinazolines; Structure-Activity Relationship; Trimetrexate | 1989 |