quinazolines has been researched along with Gastrointestinal Stromal Tumors in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 7 (70.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arnaldez, FI; Derdak, J; Derse-Anthony, C; Dombi, E; Glod, J; Helman, L; Killian, JK; Linehan, WM; Meltzer, P; Miettinen, M; Spencer, M; Srinivasan, R; Steinberg, SM; Widemann, BC; Wiener, L | 1 |
| Anjum, R; Banks, E; Barry, E; Bhavsar, D; Brown, C; Grondine, M; Guichard, SM; Jones, RDO; Kettle, JG; Pilla Reddy, V; Shao, W; Smith, A | 1 |
| Andersson, C; Blom, K; Edqvist, PH; Fryknäs, M; Gustafsson, MG; Jarvius, M; Larsson, R; Nazir, M; Nyberg, F; Nygren, P; Senkowski, W | 1 |
| Anjum, R; Barry, E; Bhavsar, D; Boyd, S; Brown, C; Campbell, A; Goldberg, K; Grondine, M; Guichard, S; Hardy, CJ; Hunt, T; Jones, RDO; Kettle, JG; Li, X; Moleva, O; Ogg, D; Overman, RC; Packer, MJ; Pearson, S; Schimpl, M; Shao, W; Smith, A; Smith, JM; Stead, D; Stokes, S; Tucker, M; Ye, Y | 1 |
| Cervera, A; Gebreyohannes, YK; Hautaniemi, S; Icay, K; Joensuu, H; Kallioniemi, O; Keskitalo, S; Kulesskiy, E; Laakkonen, P; Laaksonen, M; Lehtonen, R; Mpindi, JP; Murumägi, A; Pulkka, OP; Schöffski, P; Sihto, H; Tynninen, O; Varjosalo, M; Wennerberg, K; Wozniak, A | 1 |
| Barquin, E; Collins, B; Gardner, K; Judson, I; Jürgensmeier, JM; Leahy, M; Marotti, M; Scurr, M; Young, H | 1 |
| Cooke, LS; Kurtzman, D; Mahadevan, D; Morales, C; Ong, E; Qi, W; Stejskal, AE; Swart, R; Theiss, N; Zhu, M | 1 |
| Printz, C | 1 |
| Christoffersen, T; Dajani, O; Guren, TK; Thoresen, GH; Tveit, KM; Wisløff, F | 1 |
| Ikezoe, T; Koeffler, HP; Nishioka, C; Taguchi, H; Taguchi, T; Yang, Y; Zhu, WG | 1 |
1 review(s) available for quinazolines and Gastrointestinal Stromal Tumors
| Article | Year |
|---|---|
[Antineoplastic agents targeting tyrosine kinases].
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzamides; Cetuximab; ErbB Receptors; Erlotinib Hydrochloride; Gastrointestinal Stromal Tumors; Gefitinib; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Neoplasms; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Quinazolines; Receptor Protein-Tyrosine Kinases; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Trastuzumab | 2005 |
2 trial(s) available for quinazolines and Gastrointestinal Stromal Tumors
| Article | Year |
|---|---|
A Phase II Trial of Vandetanib in Children and Adults with Succinate Dehydrogenase-Deficient Gastrointestinal Stromal Tumor.
Topics: Adolescent; Adult; Child; Disease-Free Survival; Female; Gastrointestinal Stromal Tumors; Humans; Male; Middle Aged; Mutation; Neoplasm Metastasis; Piperidines; Progression-Free Survival; Proto-Oncogene Proteins c-kit; Quality of Life; Quinazolines; Receptor, Platelet-Derived Growth Factor alpha; Succinate Dehydrogenase; Young Adult | 2019 |
Phase II study of cediranib in patients with advanced gastrointestinal stromal tumors or soft-tissue sarcoma.
Topics: Adult; Aged; Antineoplastic Agents; Biomarkers; Female; Fluorodeoxyglucose F18; Gastrointestinal Stromal Tumors; Humans; Male; Middle Aged; Neoplasm Staging; Positron-Emission Tomography; Protein Kinase Inhibitors; Quinazolines; Sarcoma; Tomography, X-Ray Computed; Treatment Outcome | 2014 |
7 other study(ies) available for quinazolines and Gastrointestinal Stromal Tumors
| Article | Year |
|---|---|
The Pharmacokinetic-Pharmacodynamic (PKPD) Relationships of AZD3229, a Novel and Selective Inhibitor of KIT, in a Range of Mouse Xenograft Models of GIST.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Gastrointestinal Stromal Tumors; Humans; Mice; Models, Biological; Mutation; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Quinazolines; Receptor, Platelet-Derived Growth Factor alpha; Triazoles; Xenograft Model Antitumor Assays | 2020 |
Targeting tumor cells based on Phosphodiesterase 3A expression.
Topics: Adult; Aged; Antineoplastic Agents; Biomarkers, Tumor; Carrier Proteins; Cell Line, Tumor; Colonic Neoplasms; Cyclic Nucleotide Phosphodiesterases, Type 3; Female; Gastrointestinal Stromal Tumors; Gene Expression; Humans; Lung Neoplasms; Male; Melanoma; Middle Aged; Molecular Targeted Therapy; Neoplasm Proteins; Organ Specificity; Organoplatinum Compounds; Oxaliplatin; Phosphodiesterase Inhibitors; Pyridazines; Quinazolines; RNA, Messenger; Skin Neoplasms | 2017 |
Discovery of N-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1 H-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors.
Topics: Drug Discovery; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Models, Molecular; Mutant Proteins; Mutation; Protein Conformation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Quinazolines; Tissue Distribution; Triazoles; Tumor Cells, Cultured | 2018 |
Anagrelide for Gastrointestinal Stromal Tumor.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cyclic Nucleotide Phosphodiesterases, Type 3; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Gastrointestinal Stromal Tumors; High-Throughput Screening Assays; Humans; Mice; Platelet Aggregation Inhibitors; Quinazolines; Signal Transduction; Xenograft Model Antitumor Assays | 2019 |
Novel receptor tyrosine kinase targeted combination therapies for imatinib-resistant gastrointestinal stromal tumors (GIST).
Topics: Afatinib; Aged; Aged, 80 and over; Axl Receptor Tyrosine Kinase; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; ErbB Receptors; Erlotinib Hydrochloride; Female; Gastrointestinal Stromal Tumors; Gene Expression Regulation, Neoplastic; Humans; Imatinib Mesylate; Immunoblotting; Immunohistochemistry; Male; Middle Aged; Molecular Targeted Therapy; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-kit; Proto-Oncogene Proteins c-met; Pyrimidines; Quinazolines; Receptor Protein-Tyrosine Kinases; Reverse Transcriptase Polymerase Chain Reaction; Thiourea | 2015 |
Strides in personalized medicine.
Topics: Afatinib; Gastrointestinal Stromal Tumors; Humans; Lung Neoplasms; Melanoma; Mitogen-Activated Protein Kinase Kinases; Neoplasms; Phenylurea Compounds; Precision Medicine; Proto-Oncogene Proteins B-raf; Pyridines; Quinazolines | 2012 |
ZD6474 induces growth arrest and apoptosis of GIST-T1 cells, which is enhanced by concomitant use of sunitinib.
Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Apoptosis; Cell Cycle Proteins; Cell Proliferation; Drug Therapy, Combination; Gastrointestinal Stromal Tumors; Humans; Indoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphoproteins; Phosphorylation; Piperidines; Protein Kinases; Proto-Oncogene Proteins c-akt; Pyrroles; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Protein S6 Kinases, 70-kDa; STAT3 Transcription Factor; Sunitinib; TOR Serine-Threonine Kinases; Tumor Cells, Cultured | 2006 |