Page last updated: 2024-08-21

quinazolines and Experimental Mammary Neoplasms

quinazolines has been researched along with Experimental Mammary Neoplasms in 42 studies

Research

Studies (42)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (4.76)	18.7374
1990's	2 (4.76)	18.2507
2000's	17 (40.48)	29.6817
2010's	18 (42.86)	24.3611
2020's	3 (7.14)	2.80

Authors

Authors	Studies
Güven, DC; Orhan, C; Şahin, K; Uçkun, FM	1
Fujiwara, Y; Hamada, A; Ohuchi, M; Ryu, S; Shimoi, T; Tamura, K; Yagishita, S; Yonemori, K	1
Grishina, M; Pathak, P; Potemkin, V; Rimac, H; Verma, A	1
Katsuta, E; Rashid, OM; Takabe, K	1
Bode, A; Grubbs, CJ; Juliana, MM; Lubet, RA; Moeinpour, F; Steele, VE	1
Arteaga, CL; Balko, JM; Cheng, H; Cook, RS; Kuba, MG; Owens, P; Perou, CM; Pfefferle, AD; Rexer, BN; Sánchez, V; Young, CD; Zhao, JJ	1
Askeland, RW; Cyr, AR; Gillum, MP; Spanheimer, PM; Weigel, RJ; Woodfield, GW	1
Krop, IE; Lin, NU; Liu, P; Roberts, TM; Spangle, JM; Von, T; Wang, Q; Winer, EP; Zhao, JJ	1
Coarfa, C; Edwards, DP; Hilsenbeck, SG; Holdman, XB; Huang, S; Mo, Q; Pond, A; Rajapakshe, K; Rosen, JM; Welte, T; Zhang, X	1
Chen, X; Ding, L; Jin, L; Liang, GK; Wu, HH; Yao, ZT; Zhang, JQ	1
Bégin, LR; Bourque, G; Caron, M; Deblois, G; Giguère, V; Gravel, SP; Labbé, DP; Muller, WJ; Park, M; Savage, P; Smith, HW; St-Pierre, J; Tam, IS; Tremblay, ML	1
Amici, A; Andreani, C; Bartolacci, C; Belletti, B; Elexpuru Zabaleta, M; Galeazzi, R; Gambini, V; Garulli, C; Hysi, A; Iezzi, M; Kalogris, C; Marchini, C; Orlando, F; Pietrella, L; Provinciali, M; Tilio, M; Wang, J	1
Back, JB; Heng, HH; Jacob, JB; Jones, RF; Piechocki, MP; Wei, WZ; Whittington, PJ	1
Brown, PH; Gilmer, TM; Hill, JL; Hilsenbeck, SG; Kim, HT; Li, Y; Osborne, CK; Sexton, KR; Shen, Q; Strecker, TE; Wang, C; Zhang, Y	1
Bissonette, R; Brown, PH; Hill, J; Hilsenbeck, SG; Kittrell, F; Medina, D; Zhang, Y	1
Abba, MC; Aldaz, CM; Bissonnette, RP; Brown, PH; Gaddis, S; Hill, J; Hu, Y; Kittrell, FS; Levy, CC; Medina, D	1
Chen, Y; Gonzalez-Angulo, A; Guggisberg, N; Hennessy, B; Jorda, M; Mills, GB; Slingerland, JM; Tan, CK	1
Arteaga, CL; Boimel, PJ; Coniglio, SJ; Hynes, NE; Kedrin, D; Segall, JE; Wyckoff, J	1
Ballestrero, A; Cea, M; Garuti, A; Moran, E; Nencioni, A; Passalacqua, M; Patrone, F; Pistoia, V; Raffaghello, L; Soncini, D; Zoppoli, G	1
Angelini, PD; Arribas, J; Aura, C; Baselga, J; Cameron, D; Chandarlapaty, S; Ellis, C; Gagnon, R; Geyer, C; Gomez, H; Guzman, M; Jimenez, J; Koehler, M; Parra, JL; Prudkin, L; Rosen, N; Sánchez, G; Scaltriti, M	1
Durbin, JE; Koromilas, AE; Muller, WJ; Raven, JF; Tremblay, ML; Wang, S; Williams, V	1
Burga, LN; Hofstatter, EW; Hu, H; Juvekar, A; Troyan, SL; Tung, NM; Wulf, GM	1
Brahimi, F; Golabi, N; Huang, Y; Jean-Claude, BJ; Larroque-Lombard, AL; Qiu, Q; Rachid, Z	1
Blanchard, Z; Elshamy, WM; Hernandez, B; Horio, D; Killeen, J; Luk, H; Malik, R; Maric, C; Mullins, N	1
Boult, JK; Elvin, P; Gilmour, LD; Halliday, J; Jacobs, V; Jamin, Y; Robinson, SP; Ryan, AJ; Walker-Samuel, S; Waterton, JC	1
Deng, X; Erfani, SF; Hemler, ME; Hoff, J; Jin, H; Kaetzel, DM; Li, Q; Novak, M; Rabinovitz, I; Sharma, C; Sonnenberg, A; Stipp, CS; Yang, H; Yang, XH; Yi, Y; Zhou, P	1
Aronson, AB; Bose, R; Ding, L; Ellis, MJ; Goel, N; Kavuri, SM; Koboldt, DC; Li, S; Ma, CX; Mardis, ER; Monsey, J; Searleman, AC; Shen, D; Shen, W	1
Morris, C	1
Begum, K; Hirai, S; Kikuchi, H; Kim, HS; Miyazawa, Y; Oshima, Y; Tasaka, H; Wataya, Y; Yamamoto, K	1
Campiglio, M; Ménard, S; Normanno, N	1
Gear, RB; Heffelfinger, SC; LaDow, K; Schneider, J; Warshawsky, D; Yan, M	1
Arteaga, CL; Caldwell, RL; Caprioli, RM; Dugger, TC; Forbes, JT; Guix, M; Reyzer, ML; Ritter, CA	1
Bijnsdorp, IV; Comijn, EM; Gmeiner, WH; Padron, JM; Peters, GJ	1
Mu, D; Song, X; Sun, X; Wang, H; Yang, G; Yu, J; Zhao, S	1
Bode, AM; Christov, K; Ericson, ME; Grubbs, CJ; Juliana, MM; Lubet, RA; Steele, VE; Szabo, E	1
Piechocki, MP	1
DeGoeij, K; Mester, J; Sluyser, M	1
Arteaga, CL; Coffey, RJ; Forbes, JT; Lenferink, AE; Shawver, LK; Simpson, JF	1
Klar, U; Lichtner, RB; Menrad, A; Schneider, MR; Sommer, A	1
Galivan, J; Malik, ND; Piper, JR; Rhee, MS; Sirotnak, FM	1
Bissery, MC; Corbett, TH; Luk, GD; Mucci-LoRusso, P; Plowman, J; Polin, L; Valeriote, F	1
Modest, EJ; Rosowsky, A	1

Reviews

3 review(s) available for quinazolines and Experimental Mammary Neoplasms

Article	Year
Data-Driven identification of chemopreventive agents for breast cancer Turkish journal of medical sciences, 2020, 11-03, Volume: 50, Issue:SI-2 Topics: Amides; Animals; Antineoplastic Agents; Breast Neoplasms; Chemoprevention; Female; Humans; Mammary Neoplasms, Experimental; Mice; Nitriles; Protein Kinase Inhibitors; Quinazolines	2020
The role of EGFR-directed therapy in the treatment of breast cancer. Breast cancer research and treatment, 2002, Volume: 75 Suppl 1 Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Gefitinib; Humans; Mammary Neoplasms, Experimental; Quinazolines	2002
Synthesis and biological activity of tricyclic antifolate compounds with fixed geometry. Annals of the New York Academy of Sciences, 1971, Nov-30, Volume: 186 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma; Cell Line; Chickens; Enterococcus faecalis; Folic Acid Antagonists; Humans; Leukemia L1210; Liver; Malaria; Mammary Neoplasms, Experimental; Mice; Mouth Neoplasms; Pyrimethamine; Quinazolines; Structure-Activity Relationship	1971

Other Studies

39 other study(ies) available for quinazolines and Experimental Mammary Neoplasms

Article	Year
Visualization of the distribution of nanoparticle-formulated AZD2811 in mouse tumor model using matrix-assisted laser desorption ionization mass spectrometry imaging. Scientific reports, 2020, 09-23, Volume: 10, Issue:1 Topics: Acetanilides; Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Carriers; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Nanoparticles; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Quinazolines; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2020
Hybrid Quinazoline 1,3,5-Triazines as Epidermal Growth Factor Receptor (EGFR) Inhibitors with Anticancer Activity: Design, Synthesis, and Computational Study. ChemMedChem, 2021, 03-03, Volume: 16, Issue:5 Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; ErbB Receptors; Female; Humans; Mammary Neoplasms, Experimental; Models, Molecular; Molecular Structure; Protein Kinase Inhibitors; Quinazolines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Triazines; Tumor Cells, Cultured	2021
Murine breast cancer mastectomy model that predicts patient outcomes for drug development. The Journal of surgical research, 2017, Volume: 219 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Benzodioxoles; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Luminescent Measurements; Lung; Lung Neoplasms; Mammary Neoplasms, Experimental; Mastectomy, Radical; Mice, Inbred BALB C; Neoplasm Metastasis; Quinazolines	2017
Daily or weekly dosing with EGFR inhibitors, gefitinib and lapatinib, and AKt inhibitor MK2206 in mammary cancer models. Oncology reports, 2018, Volume: 40, Issue:3 Topics: Animals; Disease Models, Animal; Drug Administration Schedule; ErbB Receptors; Female; Gefitinib; Heterocyclic Compounds, 3-Ring; Lapatinib; Male; Mammary Neoplasms, Experimental; Mice; Mice, Knockout; Protein Kinase Inhibitors; Quinazolines; Rats; Rats, Sprague-Dawley; Triazoles	2018
Conditional loss of ErbB3 delays mammary gland hyperplasia induced by mutant PIK3CA without affecting mammary tumor latency, gene expression, or signaling. Cancer research, 2013, Jul-01, Volume: 73, Issue:13 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Class I Phosphatidylinositol 3-Kinases; Female; Gene Expression; Humans; Hyperplasia; Lapatinib; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Mice, Transgenic; Mutation, Missense; Neoplasm Transplantation; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Binding; Quinazolines; Receptor, ErbB-2; Receptor, ErbB-3; Signal Transduction; Transcriptome; Tumor Burden	2013
Distinct pathways regulated by RET and estrogen receptor in luminal breast cancer demonstrate the biological basis for combination therapy. Annals of surgery, 2014, Volume: 259, Issue:4 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Estrogen Receptor alpha; Female; Flow Cytometry; Humans; Indoles; Mammary Neoplasms, Experimental; MAP Kinase Signaling System; MCF-7 Cells; Mice; Piperidines; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-ret; Pyrroles; Quinazolines; Random Allocation; Signal Transduction; Sunitinib; Tamoxifen; Transcription Factor AP-2	2014
PI3K-p110α mediates resistance to HER2-targeted therapy in HER2+, PTEN-deficient breast cancers. Oncogene, 2016, 07-07, Volume: 35, Issue:27 Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Class I Phosphatidylinositol 3-Kinases; Drug Resistance, Neoplasm; Female; Humans; Lapatinib; Mammary Neoplasms, Experimental; Mice, Knockout; Molecular Targeted Therapy; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Quinazolines; Receptor, ErbB-2; Signal Transduction; Thiazoles; Tumor Burden; Xenograft Model Antitumor Assays	2016
Upregulation of EGFR signaling is correlated with tumor stroma remodeling and tumor recurrence in FGFR1-driven breast cancer. Breast cancer research : BCR, 2015, Nov-18, Volume: 17 Topics: Animals; Breast Neoplasms; Collagen; ErbB Receptors; Female; Lapatinib; Mammary Neoplasms, Experimental; Mice; Neoplasm Recurrence, Local; Phenylurea Compounds; Pyrimidines; Quinazolines; Receptor, Fibroblast Growth Factor, Type 1; Signal Transduction; Stromal Cells; Tenascin; Up-Regulation; Wnt1 Protein	2015
[Combination of lapatinib with chlorogenic acid inhibits breast cancer metastasis by suppressing macrophage M2 polarization]. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2015, Volume: 44, Issue:5 Topics: Animals; Chlorogenic Acid; Female; Lapatinib; Lung Neoplasms; Macrophages; Mammary Neoplasms, Experimental; Mice; Neoplasm Metastasis; Quinazolines	2015
ERRα mediates metabolic adaptations driving lapatinib resistance in breast cancer. Nature communications, 2016, 07-12, Volume: 7 Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Survival; Drug Resistance, Neoplasm; ERRalpha Estrogen-Related Receptor; Humans; Lapatinib; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; MCF-7 Cells; Mice; Quinazolines; Receptor, ErbB-2; Receptors, Estrogen; Retroviridae Infections; Signal Transduction; TOR Serine-Threonine Kinases; Tumor Virus Infections	2016
Irreversible inhibition of Δ16HER2 is necessary to suppress Δ16HER2-positive breast carcinomas resistant to Lapatinib. Cancer letters, 2016, 10-10, Volume: 381, Issue:1 Topics: Alternative Splicing; Animals; Benzodioxoles; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Genetic Predisposition to Disease; Humans; Inhibitory Concentration 50; Lapatinib; Mammary Neoplasms, Experimental; Mice, Transgenic; Phenotype; Protein Isoforms; Protein Kinase Inhibitors; Quinazolines; Quinazolinones; Receptor, ErbB-2; Signal Transduction; Time Factors	2016
DNA vaccination controls Her-2+ tumors that are refractory to targeted therapies. Cancer research, 2008, Sep-15, Volume: 68, Issue:18 Topics: Animals; Antibodies, Monoclonal; Cancer Vaccines; Cell Growth Processes; Female; Gefitinib; Karyotyping; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Quinazolines; Receptor, ErbB-2; Signal Transduction; T-Lymphocytes, Cytotoxic; Tyrphostins; Vaccines, DNA	2008
Effect of lapatinib on the development of estrogen receptor-negative mammary tumors in mice. Journal of the National Cancer Institute, 2009, Jan-21, Volume: 101, Issue:2 Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cyclin D1; Epidermal Growth Factor; Epiregulin; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Humans; Lapatinib; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Precancerous Conditions; Protein Kinase Inhibitors; Quinazolines; Receptor, ErbB-2; Receptors, Estrogen; RNA, Messenger; Signal Transduction	2009
Prevention of tumorigenesis in p53-null mammary epithelium by rexinoid bexarotene, tyrosine kinase inhibitor gefitinib, and celecoxib. Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:2 Topics: Animals; Anticarcinogenic Agents; Bexarotene; Celecoxib; Cyclooxygenase Inhibitors; Disease Models, Animal; ErbB Receptors; Female; Gefitinib; Immunoenzyme Techniques; Incidence; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Knockout; Pyrazoles; Quinazolines; Sulfonamides; Tetrahydronaphthalenes; Tumor Suppressor Protein p53	2009
Identification of modulated genes by three classes of chemopreventive agents at preneoplastic stages in a p53-null mouse mammary tumor model. Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:2 Topics: Animals; Anticarcinogenic Agents; Bexarotene; Biomarkers, Tumor; Celecoxib; Cyclooxygenase Inhibitors; Disease Models, Animal; ErbB Receptors; Female; Gefitinib; Gene Expression Profiling; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Precancerous Conditions; Pyrazoles; Quinazolines; Sulfonamides; Tetrahydronaphthalenes; Tumor Protein, Translationally-Controlled 1; Tumor Suppressor Protein p53	2009
Combined Src and aromatase inhibition impairs human breast cancer growth in vivo and bypass pathways are activated in AZD0530-resistant tumors. Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, May-15, Volume: 15, Issue:10 Topics: Anastrozole; Animals; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Benzodioxoles; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; CSK Tyrosine-Protein Kinase; Cyclin-Dependent Kinase Inhibitor p27; Drug Resistance, Neoplasm; Female; Humans; Immunohistochemistry; Ki-67 Antigen; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinases; Nitriles; Phosphatidylinositol 3-Kinases; Protein-Tyrosine Kinases; Quinazolines; Signal Transduction; src-Family Kinases; Triazoles; Tumor Burden; Xenograft Model Antitumor Assays	2009
ERBB1 and ERBB2 have distinct functions in tumor cell invasion and intravasation. Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Jun-01, Volume: 15, Issue:11 Topics: Animals; Benzothiazoles; Cell Line, Tumor; Cell Movement; ErbB Receptors; Female; Gefitinib; Humans; Lapatinib; Mammary Neoplasms, Experimental; Mice; Mice, SCID; Neoplasm Invasiveness; Neoplasm Metastasis; Phosphorylation; Quinazolines; Receptor, ErbB-2; Tyrphostins; Xenograft Model Antitumor Assays	2009
Grb7 upregulation is a molecular adaptation to HER2 signaling inhibition due to removal of Akt-mediated gene repression. PloS one, 2010, Feb-02, Volume: 5, Issue:2 Topics: Adaptation, Physiological; Animals; Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Survival; Female; Gene Expression Regulation, Neoplastic; GRB7 Adaptor Protein; Humans; Lapatinib; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinazolines; Receptor, ErbB-2; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; Transplantation, Heterologous; Up-Regulation	2010
Clinical benefit of lapatinib-based therapy in patients with human epidermal growth factor receptor 2-positive breast tumors coexpressing the truncated p95HER2 receptor. Clinical cancer research : an official journal of the American Association for Cancer Research, 2010, May-01, Volume: 16, Issue:9 Topics: 3T3 Cells; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Deoxycytidine; ErbB Receptors; Female; Fluorouracil; Humans; Immunoblotting; In Situ Hybridization, Fluorescence; Lapatinib; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Protein Kinase Inhibitors; Quinazolines; Randomized Controlled Trials as Topic; Receptor, ErbB-2; Survival Analysis; Treatment Outcome; Xenograft Model Antitumor Assays	2010
Stat1 is a suppressor of ErbB2/Neu-mediated cellular transformation and mouse mammary gland tumor formation. Cell cycle (Georgetown, Tex.), 2011, Mar-01, Volume: 10, Issue:5 Topics: Animals; Antineoplastic Agents; Cell Line; Cell Transformation, Neoplastic; Chlorocebus aethiops; Disease Progression; Female; Gefitinib; Humans; Lapatinib; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Phosphorylation; Quinazolines; Receptor, ErbB-2; Signal Transduction; STAT1 Transcription Factor; Transplantation, Heterologous	2011
Loss of BRCA1 leads to an increase in epidermal growth factor receptor expression in mammary epithelial cells, and epidermal growth factor receptor inhibition prevents estrogen receptor-negative cancers in BRCA1-mutant mice. Breast cancer research : BCR, 2011, Mar-11, Volume: 13, Issue:2 Topics: Aldehyde Dehydrogenase 1 Family; Animals; BRCA1 Protein; Breast; Cell Line, Tumor; Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; Erlotinib Hydrochloride; Female; Genes, BRCA1; Genes, p53; Humans; Isoenzymes; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred C57BL; Mice, Knockout; Protein Kinase Inhibitors; Quinazolines; Receptors, Estrogen; Retinal Dehydrogenase; RNA Interference	2011
A bioanalytical investigation on the exquisitely strong in vitro potency of the EGFR-DNA targeting type II combi-molecule ZR2003 and its mitigated in vivo antitumour activity. Journal of pharmaceutical and biomedical analysis, 2011, Nov-01, Volume: 56, Issue:3 Topics: Animals; Antinematodal Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; DNA; DNA Damage; Drug Delivery Systems; ErbB Receptors; Female; Humans; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Nitrogen Mustard Compounds; Ovarian Neoplasms; Quinazolines; Triazenes; Vulvar Neoplasms; Xenograft Model Antitumor Assays	2011
Geminin overexpression induces mammary tumors via suppressing cytokinesis. Oncotarget, 2011, Volume: 2, Issue:12 Topics: Aneuploidy; Animals; Aurora Kinase B; Aurora Kinases; Benzamides; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Chromatin; Chromosomal Proteins, Non-Histone; Cytokinesis; Female; Geminin; Histones; Humans; Mammary Neoplasms, Experimental; Mice; Mice, SCID; Mitosis; Oncogenes; Phosphorylation; Protein Serine-Threonine Kinases; Quinazolines; Spindle Apparatus	2011
False-negative MRI biomarkers of tumour response to targeted cancer therapeutics. British journal of cancer, 2012, Jun-05, Volume: 106, Issue:12 Topics: Animals; Benzodioxoles; Biomarkers, Tumor; Blood Vessels; Cell Hypoxia; Cell Line, Tumor; False Negative Reactions; Female; Humans; Magnetic Resonance Imaging; Male; Mammary Neoplasms, Experimental; Mice; Molecular Targeted Therapy; Neoplasm Transplantation; Piperidines; Prostatic Neoplasms; Proto-Oncogene Proteins pp60(c-src); Quinazolines; Rats; Vascular Endothelial Growth Factor Receptor-2	2012
Integrin-associated CD151 drives ErbB2-evoked mammary tumor onset and metastasis. Neoplasia (New York, N.Y.), 2012, Volume: 14, Issue:8 Topics: Animals; Butadienes; Cell Line, Tumor; Cell Movement; Epidermal Growth Factor; Female; Focal Adhesion Kinase 1; Humans; Integrin alpha6beta4; Lapatinib; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; Neoplasm Metastasis; Nitriles; Phosphorylation; Quinazolines; Receptor, ErbB-2; Tetraspanin 24; Transendothelial and Transepithelial Migration	2012
Activating HER2 mutations in HER2 gene amplification negative breast cancer. Cancer discovery, 2013, Volume: 3, Issue:2 Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line; Drug Resistance, Neoplasm; Female; Gene Amplification; Gene Expression; Humans; Lapatinib; Mammary Neoplasms, Experimental; MCF-7 Cells; Mice; Mice, Nude; Models, Molecular; Molecular Sequence Data; Mutation; NIH 3T3 Cells; Protein Structure, Tertiary; Quinazolines; Quinolines; Receptor, ErbB-2; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Transplantation, Heterologous	2013
Metabolites of febrifugine and its synthetic analogue by mouse liver S9 and their antimalarial activity against Plasmodium malaria parasite. Journal of medicinal chemistry, 2003, Sep-25, Volume: 46, Issue:20 Topics: Administration, Oral; Animals; Antimalarials; Antineoplastic Agents; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Liver; Mammary Neoplasms, Experimental; Mice; Nuclear Magnetic Resonance, Biomolecular; Piperidines; Plasmodium berghei; Plasmodium falciparum; Quinazolines; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured	2003
Re: Effect of epidermal growth factor receptor inhibitor on development of estrogen receptor-negative mammary tumors. Journal of the National Cancer Institute, 2004, May-05, Volume: 96, Issue:9 Topics: Animals; Antineoplastic Agents; ErbB Receptors; Female; Gefitinib; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Quinazolines	2004
Inhibition of VEGFR2 prevents DMBA-induced mammary tumor formation. Laboratory investigation; a journal of technical methods and pathology, 2004, Volume: 84, Issue:8 Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Carcinoma in Situ; DNA Primers; Female; Humans; Hyperplasia; Mammary Neoplasms, Experimental; Neovascularization, Pathologic; Piperidines; Quinazolines; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor Receptor-2	2004
Early changes in protein expression detected by mass spectrometry predict tumor response to molecular therapeutics. Cancer research, 2004, Dec-15, Volume: 64, Issue:24 Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Biomarkers, Tumor; Drug Synergism; ErbB Receptors; Erlotinib Hydrochloride; Female; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Molecular Sequence Data; Predictive Value of Tests; Protein Kinase Inhibitors; Proteome; Quinazolines; Receptor, ErbB-2; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Trastuzumab	2004
Mechanisms of action of FdUMP[10]: metabolite activation and thymidylate synthase inhibition. Oncology reports, 2007, Volume: 18, Issue:1 Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Fluorodeoxyuridylate; Fluorouracil; Folic Acid Antagonists; Glutamates; Guanine; Mammary Neoplasms, Experimental; Mice; Molecular Structure; Pemetrexed; Quinazolines; Thiophenes; Thymidylate Synthase; Tumor Cells, Cultured	2007
Assessment of 11C-labeled-4-N-(3-bromoanilino)-6,7-dimethoxyquinazoline as a positron emission tomography agent to monitor epidermal growth factor receptor expression. Cancer science, 2007, Volume: 98, Issue:9 Topics: Animals; Biomarkers, Tumor; Carbon Radioisotopes; Cell Line, Tumor; ErbB Receptors; Female; Humans; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Organ Specificity; Positron-Emission Tomography; Quinazolines	2007
Effects of gefitinib (Iressa) on mammary cancers: preventive studies with varied dosages, combinations with vorozole or targretin, and biomarker changes. Molecular cancer therapeutics, 2008, Volume: 7, Issue:4 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bexarotene; Biomarkers, Tumor; Carcinogens; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Therapy, Combination; ErbB Receptors; Female; Gefitinib; Immunoenzyme Techniques; Mammary Neoplasms, Experimental; Methylnitrosourea; Phosphorylation; Quinazolines; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes; Triazoles	2008
A stable explant culture of HER2/neu invasive carcinoma supported by alpha-Smooth Muscle Actin expressing stromal cells to evaluate therapeutic agents. BMC cancer, 2008, Apr-24, Volume: 8 Topics: Actins; Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Lobular; Cell Culture Techniques; Cell Line, Tumor; Coculture Techniques; Dose-Response Relationship, Drug; Flow Cytometry; Gefitinib; Gene Expression Regulation, Neoplastic; Genes, erbB-2; Male; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Models, Biological; Muscle, Smooth; Quinazolines; Stromal Cells	2008
Modulation of [5-125I]iododeoxyuridine incorporation into tumour and normal tissue DNA by methotrexate and thymidylate synthase inhibitors. European journal of cancer (Oxford, England : 1990), 1996, Volume: 32A, Issue:9 Topics: Animals; Antimetabolites, Antineoplastic; Dihydrouracil Dehydrogenase (NAD+); DNA, Neoplasm; Female; Fluorouracil; Idoxuridine; Intestine, Small; Iodine Radioisotopes; Liver; Mammary Neoplasms, Experimental; Methotrexate; Mice; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Quinazolines; Thiophenes; Thymidylate Synthase; Uracil	1996
Blockade of the epidermal growth factor receptor tyrosine kinase suppresses tumorigenesis in MMTV/Neu + MMTV/TGF-alpha bigenic mice. Proceedings of the National Academy of Sciences of the United States of America, 2000, Aug-15, Volume: 97, Issue:17 Topics: Animals; Butadienes; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cell Division; Cell Transformation, Neoplastic; Cyclin D1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cysteine Endopeptidases; Dimerization; DNA; Down-Regulation; ErbB Receptors; Female; Humans; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Transgenic; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Nitriles; Phosphorylation; Proteasome Endopeptidase Complex; Protein Serine-Threonine Kinases; Quinazolines; Receptor, ErbB-2; Signal Transduction; Time Factors; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tumor Suppressor Proteins; Tyrphostins	2000
Signaling-inactive epidermal growth factor receptor/ligand complexes in intact carcinoma cells by quinazoline tyrosine kinase inhibitors. Cancer research, 2001, Aug-01, Volume: 61, Issue:15 Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Squamous Cell; Cell Division; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Gefitinib; Humans; Kinetics; Ligands; Lung Neoplasms; Mammary Neoplasms, Experimental; Phthalimides; Quinazolines; Rats; Signal Transduction; Tumor Cells, Cultured	2001
Synthesis and antifolate evaluation of the 10-propargyl derivatives of 5-deazafolic acid, 5-deazaaminopterin, and 5-methyl-5-deazaaminopterin. Journal of medicinal chemistry, 1992, Jan-24, Volume: 35, Issue:2 Topics: Aminopterin; Animals; Cell Division; Folic Acid; Folic Acid Antagonists; Humans; Leukemia L1210; Mammary Neoplasms, Experimental; Mice; Quinazolines; Thymidylate Synthase; Tumor Cells, Cultured	1992
Activity of batracylin (NSC-320846) against solid tumors of mice. Investigational new drugs, 1989, Volume: 7, Issue:4 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Intraductal, Noninfiltrating; Cell Survival; Cells, Cultured; Colonic Neoplasms; Drug Administration Schedule; Drug Screening Assays, Antitumor; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Pancreatic Neoplasms; Quinazolines; Tumor Cells, Cultured	1989