quinazolines has been researched along with Experimental Leukemia in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (58.82) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bullinger, L; Chen, J; Fröhling, S; Gilliland, DG; Golub, TR; Gu, TL; Lee, BH; Monti, S; Tam, WF; Wang, A | 1 |
| Billups, CA; Carol, H; Gorlick, R; Houghton, PJ; Keir, ST; Kolb, EA; Lock, R; Maris, JM; Morton, CL; Reynolds, CP; Smith, MA | 1 |
| Abe, K; Giese, NA; Hollenbach, SJ; Hutchaleelaha, A; Lambing, JL; Pandey, A; Rose, JW; Scarborough, RM; Seroogy, JM; Volkots, DL; Yu, JC | 1 |
| Courtright, J; Gorlick, R; Houghton, PJ; Keir, ST; Kolb, EA; Lock, R; Maris, JM; Morton, CL; Reynolds, CP; Smith, MA; Tajbakhsh, M; Wu, J | 1 |
| Dedhar, S; Freisheim, JH; Goldie, JH; Hynes, JB | 1 |
| Holland, JF; Kamen, BA; Ohnoshi, T; Ohnuma, T; Scanlon, K; Takahashi, I | 1 |
| McCormack, JJ | 1 |
| Hamel, E; Lee, KH; Lin, CM; Paull, KD; Plowman, J; Wang, HK | 1 |
| Aherne, GW; Hardcastle, A; Jackman, AL; Raynaud, F | 1 |
| Atassi, G; Baron, M; Bissery, MC; Cros, S; Gebel-Servolles, P; Giorgi-Renault, S; Lavelle, F; Paoletti, C; Renault, J | 1 |
| Holland, JF; Kano, Y; Ohnuma, T | 1 |
| Dykes, DJ; Griswold, DP; Leopold, WR | 1 |
| Atassi, G; Dykes, DJ; Harrison, SD; Kabbe, HJ; Narayanan, VL; Paull, KD; Plowman, J; Yoder, OC | 1 |
| Danenberg, PV; Pogolotti, AL; Santi, DV | 1 |
| Amand, RS; Chen, KK; Modest, EJ; Rosowsky, A | 1 |
| Buskirk, HH; Li, LH; Moxley, TE; Neil, GL | 1 |
| Hutchison, DJ; Schmid, FA; Shimoyama, M | 1 |
1 review(s) available for quinazolines and Experimental Leukemia
| Article | Year |
|---|---|
Dihydrofolate reductase inhibitors as potential drugs.
Topics: Aminopterin; Animals; Antimalarials; Bacterial Infections; Biological Transport; Drug Interactions; Folic Acid; Folic Acid Antagonists; Helminthiasis; Humans; Immunosuppressive Agents; Leukemia, Experimental; Liver; Methotrexate; Mice; Mycoses; Neoplasms; Protozoan Infections; Psoriasis; Quinazolines; Rats; Receptors, Drug; Trypanosoma cruzi | 1981 |
16 other study(ies) available for quinazolines and Experimental Leukemia
| Article | Year |
|---|---|
Id1 is a common downstream target of oncogenic tyrosine kinases in leukemic cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzamides; Cell Line, Tumor; Cell Transformation, Neoplastic; Gene Expression; HL-60 Cells; Humans; Imatinib Mesylate; Inhibitor of Differentiation Protein 1; K562 Cells; Leukemia; Leukemia, Experimental; Mice; Oncogenes; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Quinazolines; RNA, Small Interfering; Signal Transduction | 2008 |
Initial testing (stage 1) of the kinesin spindle protein inhibitor ispinesib by the pediatric preclinical testing program.
Topics: Animals; Antimitotic Agents; Antineoplastic Agents; Benzamides; Cell Line, Tumor; Female; Glioblastoma; Humans; Injections, Intraperitoneal; Kinesins; Leukemia, Experimental; Mice; Mice, Inbred BALB C; Mice, SCID; Osteosarcoma; Quinazolines; Rhabdoid Tumor; Rhabdomyosarcoma; Sarcoma, Ewing; Single-Blind Method; Spindle Apparatus; Tumor Stem Cell Assay; Wilms Tumor; Xenograft Model Antitumor Assays | 2009 |
Identification of orally active, potent, and selective 4-piperazinylquinazolines as antagonists of the platelet-derived growth factor receptor tyrosine kinase family.
Topics: Administration, Oral; Animals; Biological Availability; Dogs; Enzyme Inhibitors; Female; fms-Like Tyrosine Kinase 3; Humans; In Vitro Techniques; Leukemia, Experimental; Leukemia, Myelomonocytic, Chronic; Macaca fascicularis; Male; Mice; Mice, Nude; Microsomes, Liver; Mutation; Phosphorylation; Piperazines; Plasma; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-kit; Quinazolines; Rats; Rats, Inbred Lew; Receptor Protein-Tyrosine Kinases; Receptor, Platelet-Derived Growth Factor beta; Receptors, Platelet-Derived Growth Factor; Structure-Activity Relationship; Tumor Cells, Cultured | 2002 |
Initial testing of the VEGFR inhibitor AZD2171 by the pediatric preclinical testing program.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Line, Tumor; Female; Humans; Leukemia, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Neoplasm Proteins; Neoplasms, Experimental; Neovascularization, Pathologic; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Quinazolines; Random Allocation; Receptors, Vascular Endothelial Growth Factor; Xenograft Model Antitumor Assays | 2008 |
Inhibition of a methotrexate-insensitive dihydrofolate reductase from L5178Y cells by substituted triazines and quinazolines.
Topics: Animals; Cells, Cultured; Folic Acid Antagonists; Leukemia L5178; Leukemia, Experimental; Methotrexate; Mice; Quinazolines; Triazines | 1983 |
Establishment of methotrexate-resistant human acute lymphoblastic leukemia cells in culture and effects of folate antagonists.
Topics: Animals; Biological Transport; Cells, Cultured; Drug Interactions; Drug Resistance; Folic Acid Antagonists; Humans; Kinetics; Leucovorin; Leukemia, Experimental; Leukemia, Lymphoid; Methotrexate; Quinazolines; Tetrahydrofolate Dehydrogenase | 1982 |
Antitumor 2,3-dihydro-2-(aryl)-4(1H)-quinazolinone derivatives. Interactions with tubulin.
Topics: Animals; Antineoplastic Agents; Binding, Competitive; Brain; Cattle; Cell Division; Colchicine; Growth Inhibitors; Leukemia, Experimental; Mice; Podophyllotoxin; Protein Binding; Quinazolines; Structure-Activity Relationship; Styrenes; Tubulin; Vinblastine | 1996 |
Immunoreactive dUMP and TTP pools as an index of thymidylate synthase inhibition; effect of tomudex (ZD1694) and a nonpolyglutamated quinazoline antifolate (CB30900) in L1210 mouse leukaemia cells.
Topics: Animals; Deoxyuracil Nucleotides; Dipeptides; Dose-Response Relationship, Drug; Folic Acid Antagonists; Leukemia, Experimental; Mice; Mice, Inbred Strains; Quinazolines; Radioimmunoassay; Thiophenes; Thymidylate Synthase; Thymine Nucleotides; Tumor Cells, Cultured | 1996 |
Heterocyclic quinones. 17. A new in vivo active antineoplastic drug: 6,7-bis(1-aziridinyl)-4-[[3-(N,N-dimethylamino)propyl]amino]-5,8- quinazolinedione.
Topics: Animals; Antineoplastic Agents; Aziridines; Breast Neoplasms; Cell Division; Cell Line; Drug Screening Assays, Antitumor; Female; Humans; Leukemia L1210; Leukemia, Experimental; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Molecular Structure; Neoplasms, Experimental; Quinazolines; Sarcoma, Experimental; Structure-Activity Relationship | 1991 |
Folate requirements of methotrexate-resistant human acute lymphoblastic leukemia cell lines.
Topics: Biological Transport; Cell Line; Drug Resistance; Folic Acid; Humans; Leukemia, Experimental; Leukemia, Lymphoid; Methotrexate; Nutritional Requirements; Quinazolines; Trimetrexate | 1986 |
Therapeutic synergy of trimetrexate (CI-898) in combination with doxorubicin, vincristine, cytoxan, 6-thioguanine, cisplatin, or 5-fluorouracil against intraperitoneally implanted P388 leukemia.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Synergism; Fluorouracil; Leukemia P388; Leukemia, Experimental; Mice; Quinazolines; Thioguanine; Trimetrexate; Vincristine | 1987 |
Preclinical antitumor activity of batracylin (NSC 320846).
Topics: Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Agents; Colonic Neoplasms; Drug Evaluation, Preclinical; Injections, Intraperitoneal; Leukemia P388; Leukemia, Experimental; Mice; Mice, Inbred Strains; Quinazolines; Tumor Cells, Cultured | 1988 |
Kinetics and mechanism of interaction of 10-propargyl-5,8-dideazafolate with thymidylate synthase.
Topics: Antineoplastic Agents; Carbon Radioisotopes; Deoxyuracil Nucleotides; Folic Acid; Kinetics; Leukemia, Experimental; Protein Denaturation; Quinazolines; Spectrophotometry, Ultraviolet; Thymidylate Synthase; Tritium | 1986 |
Chemical and biological studies on 1,2-dihydro-s-triazines. 18. Synthesis of 1-(5,6- and 5,7-dichloro-2-naphthyl) derivatives and related compounds as candidate antimalarial and antitumor agents.
Topics: Animals; Antimalarials; Antineoplastic Agents; Ascites; Biguanides; Carcinoma, Squamous Cell; Cells; Chlorine; Humans; Leukemia, Experimental; Mice; Mice, Inbred DBA; Naphthalenes; Neoplasm Transplantation; Plasmodium; Plasmodium berghei; Quinazolines; Streptococcus; Transplantation, Homologous; Triazines | 1973 |
Antitumor effects of the antispermatogenic agent, 2,3-dihydro-2-(1-naphthyl)-4(1H)-quinazolinone (NSC-145669).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Benzene Derivatives; Carbon Isotopes; Cells, Cultured; DNA, Neoplasm; Female; Injections, Intraperitoneal; Injections, Subcutaneous; Ketones; Leukemia L1210; Leukemia, Experimental; Mice; Mice, Inbred Strains; Naphthalenes; Neoplasm Proteins; Neoplasm Transplantation; Organ Size; Quinazolines; Quinolines; RNA, Neoplasm; Time Factors | 1972 |
Quinazoline antifolates: dosage schedules and toxicity.
Topics: Aminopterin; Animals; Antineoplastic Agents; Body Weight; Dosage Forms; Folic Acid Antagonists; Leucovorin; Leukemia, Experimental; Male; Methotrexate; Mice; Quinazolines | 1971 |