Page last updated: 2024-08-21

quinazolines and Cytomegalovirus

quinazolines has been researched along with Cytomegalovirus in 125 studies

Research

Studies (125)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (0.80)	18.7374
1990's	0 (0.00)	18.2507
2000's	7 (5.60)	29.6817
2010's	53 (42.40)	24.3611
2020's	64 (51.20)	2.80

Authors

Authors	Studies
Baldanti, F; Campanini, G; Cassaniti, I; Fratini, A; Girelli, F; Meini, A; Novazzi, F; Palumbo, L; Paolucci, S; Plebani, A; Tebaldi, A	1
Bloor, AJC; Byrne, J; Carpenter, B; Crea, P; Duncan, N; Errico, G; Gilleece, MH; Hurst, E; Khan, A; Lovell, R; Lozano, S; Marzolini, MAV; Mehra, V; Nicholson, E; Orchard, K; Pagliuca, A; Parker, A; Peggs, KS; Pirrie, J; Publicover, A; Snowden, JA; Tholouli, E; Thomson, KJ	1
Aaltonen, S; Helanterä, I; Koivuviita, N; Lempinen, M; Ortiz, F	1
Garg, N; Jorgenson, MR; Kleiboeker, H; Mandelbrot, DA; Odorico, JS; Parajuli, S; Saddler, CM; Smith, JA	1
Cho, C; Dumke, H; Giralt, S; Han, G; Jakubowski, A; Karantoni, E; Nawar, T; Papanicolaou, G; Perales, MA; Shaffer, B; Stern, A; Su, Y; Tamari, R; Zavras, P	1
Dadwal, SS; Dickter, JK; Lee, BV; Ross, JA; Tegtmeier, BR; Zain, JM	1
Bacchus, M; Baker, AW; Berry, H; Eichenberger, EM; Ferrari, A; Kakoullis, SA; Maziarz, EK; Reynolds, JM; Saullo, JL; Snyder, LD; Steinbrink, JM; Wolfe, CR; Zaffiri, L	1
Alessandrino, EP; Baldanti, F; Bernasconi, P; Binaschi, L; Borsani, O; Caldera, D; Cassinelli, G; Colombo, AA; Ferretti, VV; Gabanti, E; Lilleri, D; Sciarra, R; Zavaglio, F	1
Alain, S; Beauvais, D; Bénard, N; Brissot, E; Ceballos, P; Chevallier, P; Coiteux, V; Ducastelle-Lepretre, S; Joris, M; Liautard, C; Marçais, A; Nguyen, S; Redjoul, R; Robin, C; Rubio, MT; Thiebaut, A; Turlure, P; Xhaard, A; Yakoub-Agha, I	1
Babushok, D; Carulli, A; Frey, NV; Freyer, CW; Ganetsky, A; Gier, S; Gill, SI; Hexner, EO; Loren, AW; Luger, SM; Mangan, JK; Martin, ME; McCurdy, SR; Perl, AE; Porter, DL; Pratz, K; Schuster, M; Smith, J; Stadtmauer, EA; Timlin, C	1
Berney, T; Brossier Pressacco, C; Finci, L; Jayo, M; Lescuyer, P; Neofytos, D; Nguyen, A; Tonoli, D; van Delden, C	1
Chen, JS; Cheng, CN; Li, SS; Shen, CF; Yeh, YH	1
Steininger, C; Weinberger, S	1
Boelens, JJ; Chan, A; Cirincione, A; Kernan, NA; Kunvarjee, B; Mathew, S; P Daukshus, N; Papanicolaou, GA; Seo, SK; Siver, M	1
Boivin, G; Goyette, N; Piret, J	1
Abboud, C; Abboud, R; Cashen, AF; Crain, M; Gao, F; Liu, LW; Olson, M; Pusic, I; Schroeder, MA; Stockerl-Goldstein, K; Vij, R; Westervelt, P; Yn, A	1
Alain, S; Feghoul, L; Frobert, E; Garrigue, I; Hantz, S; Lepiller, Q; Mirand, A; Muller, C; Sidorov, E; Tilloy, V	1
Fujita, S; Hotta, M; Ichikawa, J; Ishii, K; Ishii, Y; Ito, T; Konishi, A; Nakanishi, T; Nomura, S; Saito, R; Satake, A; Yoshimura, H	1
Chou, S; Kleiboeker, S	1
Biernacki, MA; Boeckh, M; Castor, J; Greninger, AL; Jerome, KR; Joncas-Schronce, L; Kim, Y; Martin, PJ; Perchetti, GA; Sandmaier, BM; Ueda Oshima, M; Xie, H; Zamora, D	1
Brune, W; Empting, M; Kosche, E; Ostermann, E; Potgieter, TI; Rückert, J; Schulz, T; Zhang, T	1
Haber, B; Limaye, AP	1
Benotmane, I; Caillard, S; Perrin, P	1
Ahmad, K; Aryal, S; Brown, AW; Chun, J; Cochrane, A; Desai, S; Fregoso, M; Katugaha, SB; King, C; Marinak, L; Nathan, SD; Shlobin, OA	1
Barker, J; Bhatt, V; DeRespiris, L; Giralt, SA; Griffin, M; Jakubowski, AA; Lau, C; Lin, A; Maloy, M; Papadopoulos, EB; Papanicolaou, GA; Perales, MA; Proli, A; Seo, SK; Shaffer, B; Su, Y	1
Mori, T	1
Acharya, N; Doan, T; Gonzales, JA; Shantha, JG; Tsui, E	1
Bar-On, S; Haynes, RK; Lantsberg, D; Laskov, I; Oiknine-Djian, E; Panet, A; Wolf, DG	1
Alain, S; Cazal, R; Couvreux, A; Hantz, S; Ligat, G	1
Barnard, R; Chou, S; Douglas, CM; Holder, D; Leavitt, R; Levitan, D; Maguire, M; Nickle, D; Strizki, J; Teal, V; van Alewijk, DCJG; van Doorn, LJ; Wan, H	1
James, SH	1
Han, SH; Hong, YM; Jo, H; Jo, JH; Kwon, DE; Lee, KH; Lim, BJ; Min, SY	1
Badshah, CS; Butterton, JR; Chemaly, RF; Leavitt, RY; Ljungman, PT; Marty, FM; Teal, VL; Wan, H; Yeh, WW	1
Ferreira, VH; Humar, A; Husain, S; Kumar, D; Phoompoung, P; Tikkanen, J; Viswabandya, A	1
Acosta, E; Bowlin, T; Brooks, J; Chiang, L; Hussein, I; Kauvar, LM; Kimberlin, D; Leavitt, R; Prichard, M; Whitley, R	1
Anderson, A; Camargo, J; Komanduri, K; Morris, M; Raja, M; Vazquez, N	1
Alain, S; Berceanu, A; Ducastelle-Lepretre, S; Feghoul, L; Frobert, E; Girault, S; Guerin, E; Hantz, S; Le Goff, J; Lepiller, Q; Michonneau, D; Peytavin, G; Tilloy, V	1
Brown, JW; Domingo, W; Efron, B; Johnsrud, JJ; Narasimhan, B; Nguyen, IT	1
Berney, T; Elkrief, L; Kronig, I; Neofytos, D; Van Delden, C	1
Alsumali, A; Chemaly, RF; Graham, J; Jiang, Y; Merchant, S; Miles, L; Schelfhout, J; Tang, Y; Yang, J	1
Burgmann, H; Fisecker, L; Schubert, L; Steininger, C; Thalhammer, F	1
Gerull, S; Gwerder, M; Halter, J; Heim, D; Hirsch, HH; Khanna, N; Lengerke, C; Leuzinger, K; Medinger, M; Passweg, J; Studer, U; Tsakiris, DA	1
Abramova, R; Assal, A; Bansal, R; Gordillo, CA; Mapara, MY; Pereira, MR; Reshef, R	1
Cho, C; DeRespiris, L; Devlin, SM; Figgins, B; Flynn, J; Giralt, SA; Griffin, M; Jakubowski, AA; Lau, C; Lin, A; Papadopoulos, EB; Perales, MA; Proli, A; Seo, SK; Shaffer, B; Tamari, R	1
Akashi, K; Aoki, T; Eto, T; Harada, T; Henzan, H; Ito, Y; Jinnouchi, F; Kadowaki, M; Kamimura, T; Kato, K; Kohno, K; Kuriyama, T; Miyamoto, T; Mori, Y; Nagafuji, K; Odawara, J; Ogawa, R; Ohno, Y; Takase, K; Takenaka, K; Ueno, T; Yoshimoto, G	1
Alsumali, A; Chan, TS; Chau, RW; Chen, WT; Cheng, SS; Hsu, DC; Kang, SH; Kwong, YL	1
Bittel, P; Dahdal, S; Hirzel, C; Hofmann, E; Manuel, O; Sidler, D; Suter-Riniker, F; Walti, LN	1
Derigs, P; Dreger, P; Hegenbart, U; Luft, T; Müller-Tidow, C; Radujkovic, A; Schmitt, M; Schnitzler, P; Schöning, T; Schönland, SO; Schubert, ML	1
Biffi, A; Blijlevens, N; de la Camara, R; Fagioli, F; Galaverna, F; Gil, L; Groll, AH; Holler, E; Junghanss, C; Knelange, N; Lioure, B; Ljungman, P; Medinger, M; Mielke, S; Mikulska, M; Nikolousis, E; Rodriguez, MAB; Solano, C; Šrámek, J; Styczyński, J; Taskinen, M; Tridello, G; Tsirigotis, P; Wendel, L; Xhaard, A	1
Baldanti, F; Bernasconi, P; Bonifazi, F; Campanini, G; Cassaniti, I; Ciceri, F; Colombo, AA; Girmenia, C; Greco, R; Iori, AP; Lazzarotto, T; Malagola, M; Peccatori, J; Percivalle, E; Piccirilli, G; Russo, D	1
Brown, A; Gupta, G; Kumar, D; Song, C; Thacker, L; Winstead, RJ; Yakubu, I	1
Chu, X; Kothare, P; Kropeit, D; McCrea, JB; Menzel, K	1
Akoto, B; Boeckh, M; De Rosa, SC; Duke, ER; Edmison, BC; Finak, G; Jerome, KR; Kiener, R; Leisenring, WM; Mielcarek, M; Schiffer, JT; Stevens-Ayers, T; Wagner, R; Xie, H; Zamora, D	1
D'Addona, M; Ferrara, I; Fontana, R; Giudice, V; Guariglia, R; Langella, M; Martorelli, MC; Mettivier, L; Pezzullo, L; Selleri, C; Serio, B; Vaccaro, E	1
Doke, Y; Fukuda, T; Fukushi, Y; Hashimoto, H; Inamoto, Y; Nakashima, T; Yamaguchi, M	1
Gruber, J; Ingemi, AI; Khardori, N; McMahon, M; Pearston, AP; Ripley, K; Sutton, S; Wilson, TJ	1
Aitken, SL; Ariza-Heredia, EJ; Champlin, R; Chemaly, RF; Foolad, F; Handy, V; Jiang, Y; Khawaja, F; Rezvani, K; Sassine, J; Shigle, TL; Shpall, E	1
Al-Hamed, R; Arbona-Haddad, E; Chen, K; Cheng, MP; Gooptu, M; Hammond, SP; Marty, FM; McDonnell, AM; Orejas, JL; Silverman, E; Soiffer, RJ; Timblin, K	1
Chalandon, Y; Masouridi-Levrat, S; Neofytos, D; Royston, E; Royston, L; Van Delden, C	1
Barton, J; Behr, J; Kauke, T; Keppler, OT; Kneidinger, N; Meiser, B; Michel, S; Milger, K; Munker, D; Nitschko, H; Veit, T; Zoller, M	1
Müller, TF; Näf, B; Rho, E; Schachter, T; von Moos, S; Wüthrich, RP	1
Schleiss, MR	1
Descourouez, JL; Garg, N; Jorgenson, MR; Mandelbrot, DA; Odorico, JS; Parajuli, S; Saddler, CM; Smith, JA	1
Alain, S; Baumert, TF; Gourin, C; Hantz, S; Ligat, G; Muller, C	1
Einsele, H; Fuji, S; Kapp, M	1
Chou, S	3
Badshah, C; Blumberg, EA; Boeckh, M; Brown, J; Chemaly, RF; Dadwal, SS; DiNubile, MJ; Duarte, RF; Einsele, H; Haider, S; Kanda, Y; Kartsonis, NA; Katayama, Y; Leavitt, RY; Ljungman, P; Maertens, J; Marty, FM; Mullane, KM; Murata, Y; Snydman, DR; Teal, VL; Ullmann, AJ; Wan, H	1
Clark, AE; Gordts, PLSM; Sabalza, M; Spector, DH	1
Kim, ES	1
Badshah, C; Maertens, J; Marty, FM	1
Humar, A; Kumar, D; L’Huillier, AG	1
Mori, J; Oshima, K; Tanimoto, T	1
Gentile, G; Micozzi, A	1
Razonable, RR	1
Gagelmann, N; Kröger, N; Ljungman, P; Styczynski, J	1
Chou, S; Ercolani, RJ; Satterwhite, LE	1
Meesing, A; Razonable, RR	1
Arasaratnam, RJ; Chong, PP; Drazner, MH; Garg, S; Peltz, M; Prokesch, BC; Teiber, D	1
Aitken, SL; Chemaly, RF; Foolad, F	1
Chen, X; Li, H; Zhou, S	1
Knoll, BM; Phillips, A; Seiter, K; Soave, R	1
Bogner, E; Drach, JC; Gentry, BG	1
Deleenheer, B; Maertens, J; Spriet, I	1
Dadwal, SS	1
Arif, S; Baker, AW; Cox, G; Grewal, DS; Maziarz, EK; Saullo, JH; Strand, A; Turner, N; Wolfe, CR	1
Calcoen, B; Hecke, SV; Lagrou, K; Maertens, J	1
Boivin, G; Piret, J	1
Sinkó, J	1
Eto, T; Ogawa, M	1
Frange, P; Leruez-Ville, M	1
Turner, NA; Wolfe, CR	1
Jung, S; Michel, D; Michel, M; Stamminger, T	1
Papanicolaou, GA; Perales, MA	1
Badshah, C; Butterton, JR; Chemaly, RF; Kartsonis, NA; Leavitt, RY; Ljungman, P; Maertens, J; Marty, FM; Murata, Y; Sarratt, K; Schmitt, M; Teal, VL; Wan, H	1
Andre, P; Asner, SA; Buclin, T; Decosterd, LA; Gengler, C; Jaton-Ogay, K; Mercier, T; Meylan, P; Murray, K; Natterer, J; Opota, O; Pérez Marín, M; Perez, MH; Rizzi, M	1
Colberg-Poley, AM; Donaldson, EF; Hodowanec, AC; Komatsu, TE; O'Rear, JJ; Pikis, A; Singer, ME	1
Kotton, CN	1
Arnold, P; Barton, J; Behr, J; Ceelen, F; Kauke, T; Kneidinger, N; Michel, S; Milger, K; Munker, D; Schiopu, S; Veit, T; Zoller, M	1
Arns, W; Beelen, DW; Budde, K; Dürr, M; Fischereder, M; Gwinner, W; Hummel, J; Lischka, P; Michel, D; Mühlfeld, A; Renders, L; Rübsamen-Schaeff, H; Stangl, M; Stoelben, S; Suwelack, B; Witzke, O; Zimmermann, H	1
Goldner, T; Hempel, C; Lischka, P; Ruebsamen-Schaeff, H; Zimmermann, H	1
Peggs, KS; Sellar, RS	1
Deluca, KA; Jaskoll, T; Melnick, M	1
Griffiths, P; Lumley, S	1
Boeckh, M; Murphy, WJ; Peggs, KS	1
Goldner, T; Lischka, P; Zimmermann, H	1
Lischka, P; Wildum, S; Zimmermann, H	1
Lischka, P; Michel, D; Zimmermann, H	1
Holder, D; Lischka, P; Zhang, D; Zimmermann, H	1
Gerna, G; Lilleri, D	1
Bahsi, H; Chou, S; Hamilton, S; Haupt, VJ; Hutterer, C; Marschall, M; Naing, Z; Örfi, L; Örfi, Z; Rawlinson, W; Socher, E; Steingruber, M; Sticht, H; Thuma, N; Zeitträger, I	1
Amin, SG; Buchkovich, NJ; Cruz, L; Desai, DH; Desai, T; Ferguson, K; Streck, NT	1
Bowman, LJ; Brennan, DC; Melaragno, JI	1
Banhegyi, P; Borbely, G; Breza, N; Hegymegi-Barakonyi, B; Keri, G; Orfi, L; Pato, J; Petak, I; Varkondi, E	1
Baumeister, J; Goldner, T; Hewlett, G; Lischka, P; Paulsen, D; Ruebsamen-Schaeff, H; Wunberg, T; Zimmermann, H	1
Lischka, P; Marschall, M; Ruebsamen-Schaeff, H; Stamminger, T; Urban, A; Wildum, S; Zimmermann, H	1
Bruno, AM; Castro, A; Gil, C; Martinez, A; Otero, J; Pérez, C; Prieto, C	1
Freitag, M; Herget, T; Kupfer, R; Marschall, M; Morbitzer, M; Stamminger, T	1
Compton, T; Feire, AL; Isaacson, MK	1
Abele, S; Anderson, J; Auerochs, S; Choi, Y; Eickhoff, J; Ensminger, S; Klebl, B; Leis, M; Marschall, M; Michel, D; Rawlinson, W; Rechter, S; Schleiss, M; Scott, G; Stamminger, T	1
Angeretti, A; Cavallo, R; Gribaudo, G; Landolfo, S; Lembo, D; Mondo, A; Riera, L	1
De Andrea, M; Gribaudo, G; Johnson, LF; Landolfo, S; Lembo, D; Riera, L	1
Nightingale, SL; Young, FE	1

Reviews

19 review(s) available for quinazolines and Cytomegalovirus

Article	Year
[Management of cytomegalovirus infection after hematopoietic stem cell transplantation]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 2019, Volume: 60, Issue:9 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Hematopoietic Stem Cell Transplantation; Humans; Incidence; Quinazolines	2019
Advances in the Development of Therapeutics for Cytomegalovirus Infections. The Journal of infectious diseases, 2020, 03-05, Volume: 221, Issue:Suppl 1 Topics: Acetates; Antiviral Agents; Biomarkers; Clinical Studies as Topic; Cytomegalovirus; Cytomegalovirus Infections; Drug Development; Drug Resistance, Viral; Humans; Infectious Disease Transmission, Vertical; Quinazolines; Research Design; Sirtuins; Stem Cell Transplantation; Treatment Outcome; Viral Load	2020
Cytomegalovirus disease in hematopoietic stem cell transplant patients: current and future therapeutic options. Current opinion in infectious diseases, 2017, Volume: 30, Issue:4 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Forecasting; Hematopoietic Stem Cell Transplantation; Humans; Immunotherapy, Adoptive; Opportunistic Infections; Postoperative Complications; Quinazolines; Transplant Recipients	2017
Letermovir: First Global Approval. Drugs, 2018, Volume: 78, Issue:1 Topics: Acetates; Administration, Intravenous; Administration, Oral; Antiviral Agents; Canada; Cytomegalovirus; Cytomegalovirus Infections; Dose-Response Relationship, Drug; Drug Approval; Hematopoietic Stem Cell Transplantation; Humans; Quinazolines; Treatment Outcome; United States	2018
Role of letermovir for prevention of cytomegalovirus infection after allogeneic haematopoietic stem cell transplantation. Current opinion in infectious diseases, 2018, Volume: 31, Issue:4 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance; Hematopoietic Stem Cell Transplantation; Humans; Premedication; Quinazolines; Transplantation, Homologous	2018
Comparative Efficacy and Safety of Different Antiviral Agents for Cytomegalovirus Prophylaxis in Allogeneic Hematopoietic Cell Transplantation: A Systematic Review and Meta-Analysis. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2018, Volume: 24, Issue:10 Topics: Acetates; Acyclovir; Allografts; Antiviral Agents; Benzimidazoles; Cytomegalovirus; Cytomegalovirus Infections; Female; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Male; Quinazolines; Ribonucleosides; Risk Factors; Valacyclovir	2018
New Developments in the Management of Cytomegalovirus Infection After Transplantation. Drugs, 2018, Volume: 78, Issue:11 Topics: Acetates; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Viral; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Immunotherapy; Organ Transplantation; Quinazolines; Valganciclovir	2018
Letermovir for the prevention of cytomegalovirus infection in adult cytomegalovirus-seropositive hematopoietic stem cell transplant recipients. Expert review of clinical pharmacology, 2018, Volume: 11, Issue:10 Topics: Acetates; Adult; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Hematopoietic Stem Cell Transplantation; Humans; Quinazolines; Serologic Tests; Virus Activation	2018
Targeting the terminase: An important step forward in the treatment and prophylaxis of human cytomegalovirus infections. Antiviral research, 2019, Volume: 161 Topics: Acetates; Animals; Antiviral Agents; Clinical Trials as Topic; Cytomegalovirus; Cytomegalovirus Infections; Endodeoxyribonucleases; Humans; Quinazolines; Viral Proteins; Virus Replication	2019
Pharmacokinetic drug evaluation of letermovir prophylaxis for cytomegalovirus in hematopoietic stem cell transplantation. Expert opinion on drug metabolism & toxicology, 2018, Volume: 14, Issue:12 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Drug Interactions; Drug Resistance, Viral; Hematopoietic Stem Cell Transplantation; Humans; Quinazolines	2018
Update on prevention of cytomegalovirus in hematopoietic cell transplantation. Current opinion in infectious diseases, 2019, Volume: 32, Issue:1 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Hematopoietic Stem Cell Transplantation; Humans; Quinazolines	2019
Clinical development of letermovir and maribavir: Overview of human cytomegalovirus drug resistance. Antiviral research, 2019, Volume: 163 Topics: Acetates; Animals; Antiviral Agents; Benzimidazoles; Clinical Trials as Topic; Cytomegalovirus; Cytomegalovirus Infections; DNA, Viral; Drug Development; Drug Resistance, Viral; Humans; Quinazolines; Ribonucleosides; Viral Proteins; Virus Replication	2019
[Current treatment modalities of immunocompromised patients with cytomegalovirus infection. II. Therapeutic options and management strategies]. Orvosi hetilap, 2019, Volume: 160, Issue:10 Topics: Acetates; Acyclovir; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Foscarnet; Ganciclovir; Humans; Immunocompromised Host; Quinazolines; Stem Cell Transplantation	2019
A Fine Balance: Using Letermovir for Salvage Antiviral Treatment While Preserving Efficacy. Transplantation, 2020, Volume: 104, Issue:2 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Graft Rejection; Humans; Organ Transplantation; Quinazolines; Transplant Recipients; Treatment Outcome	2020
Therapeutic strategies for cytomegalovirus infection in haematopoietic transplant recipients: a focused update. Expert opinion on biological therapy, 2014, Volume: 14, Issue:8 Topics: Acetates; Antiviral Agents; Benzimidazoles; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Immunotherapy, Adoptive; Organophosphonates; Quinazolines; Ribonucleosides; T-Lymphocytes; Transplant Recipients; Transplantation, Homologous	2014
Cytomegalovirus. Current opinion in infectious diseases, 2014, Volume: 27, Issue:6 Topics: Acetates; Antiviral Agents; Benzimidazoles; Bone Marrow Transplantation; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Transmission, Infectious; Double-Blind Method; Female; Ganciclovir; Humans; Male; Organ Transplantation; Organophosphonates; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Infectious; Quinazolines; Randomized Controlled Trials as Topic; Ribonucleosides	2014
Recent advances in cytomegalovirus: an update on pharmacologic and cellular therapies. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2015, Volume: 21, Issue:1 Topics: Acetates; Adoptive Transfer; Animals; Antiviral Agents; Benzimidazoles; Cell- and Tissue-Based Therapy; Clinical Trials, Phase III as Topic; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Hematopoietic Stem Cell Transplantation; Humans; Isoxazoles; Killer Cells, Natural; Leflunomide; Mice; Organophosphonates; Quinazolines; Ribonucleosides; T-Lymphocytes	2015
Strategies to control human cytomegalovirus infection in adult hematopoietic stem cell transplant recipients. Immunotherapy, 2016, Volume: 8, Issue:9 Topics: Acetates; Adult; Animals; Antiviral Agents; Asymptomatic Diseases; Benzimidazoles; Clinical Trials as Topic; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Management; Gastroenteritis; Hematopoietic Stem Cell Transplantation; Humans; Immunotherapy; Monitoring, Immunologic; Organophosphonates; Pneumonia; Postoperative Complications; Quinazolines; Ribonucleosides	2016
Letermovir for the management of cytomegalovirus infection. Expert opinion on investigational drugs, 2017, Volume: 26, Issue:2 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Drug Design; Drug Resistance, Viral; Humans; Immunocompromised Host; Quinazolines	2017

Trials

8 trial(s) available for quinazolines and Cytomegalovirus

Article	Year
Outcomes of patients with detectable CMV DNA at randomization in the phase III trial of letermovir for the prevention of CMV infection in allogeneic hematopoietic cell transplantation. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2020, Volume: 20, Issue:6 Topics: Acetates; Adult; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; DNA; Hematopoietic Stem Cell Transplantation; Humans; Quinazolines; Random Allocation	2020
Drug interaction between letermovir and voriconazole after allogeneic hematopoietic cell transplantation. International journal of hematology, 2021, Volume: 113, Issue:6 Topics: Acetates; Adult; Aged; Allografts; Cytomegalovirus; Cytomegalovirus Infections; Drug Interactions; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Quinazolines; Retrospective Studies; Voriconazole	2021
Letermovir Prophylaxis for Cytomegalovirus in Hematopoietic-Cell Transplantation. The New England journal of medicine, 2017, 12-21, Volume: 377, Issue:25 Topics: Acetates; Adolescent; Adult; Aged; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; DNA, Viral; Double-Blind Method; Female; Hematopoietic Stem Cell Transplantation; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Quinazolines; Young Adult	2017
[Pharmacological and clinical effects of letermovir (Prevymis Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2019, Volume: 153, Issue:4 Topics: Acetates; Animals; Antiviral Agents; Cytomegalovirus; Humans; Mice; Quinazolines	2019
A Mortality Analysis of Letermovir Prophylaxis for Cytomegalovirus (CMV) in CMV-seropositive Recipients of Allogeneic Hematopoietic Cell Transplantation. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020, 04-10, Volume: 70, Issue:8 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Hematopoietic Stem Cell Transplantation; Humans; Quinazolines	2020
In-depth genomic analyses identified novel letermovir resistance-associated substitutions in the cytomegalovirus UL56 and UL89 gene products. Antiviral research, 2019, Volume: 169 Topics: Acetates; Amino Acid Substitution; Antiviral Agents; Cytomegalovirus; Drug Resistance, Viral; Endodeoxyribonucleases; Genomics; High-Throughput Nucleotide Sequencing; Humans; Quinazolines; Stem Cell Transplantation; Viral Proteins; Viral Structural Proteins	2019
Preemptive treatment of Cytomegalovirus infection in kidney transplant recipients with letermovir: results of a Phase 2a study. Transplant international : official journal of the European Society for Organ Transplantation, 2014, Volume: 27, Issue:1 Topics: Acetates; Adult; Aged; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; DNA, Viral; Female; Humans; Kidney Transplantation; Male; Middle Aged; Opportunistic Infections; Quinazolines; Viral Load; Viremia	2014
Characterization of Cytomegalovirus Breakthrough Events in a Phase 2 Prophylaxis Trial of Letermovir (AIC246, MK 8228). The Journal of infectious diseases, 2016, Jan-01, Volume: 213, Issue:1 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; DNA, Viral; Drug Resistance, Viral; Humans; Open Reading Frames; Quinazolines; Viral Load; Viremia	2016

Other Studies

98 other study(ies) available for quinazolines and Cytomegalovirus

Article	Year
Emergence of Letermovir-resistant HCMV UL56 mutant during rescue treatment in a liver transplant recipient with ganciclovir-resistant infection HCMV: a case report. BMC infectious diseases, 2021, Sep-23, Volume: 21, Issue:1 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Viral; Ganciclovir; Humans; Liver Transplantation; Mutation; Neoplasm Recurrence, Local; Quinazolines	2021
Letermovir prophylaxis in T-cell-depleted transplants: breakthrough and rebound infections in the postmarketing setting. Blood advances, 2021, 11-09, Volume: 5, Issue:21 Topics: Acetates; Cytomegalovirus; Cytomegalovirus Infections; Humans; Quinazolines; T-Lymphocytes	2021
Letermovir treatment for CMV infection in kidney and pancreas transplantation: A valuable option for complicated cases. Clinical transplantation, 2022, Volume: 36, Issue:2 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Ganciclovir; Humans; Kidney; Kidney Transplantation; Leukopenia; Pancreas Transplantation; Quinazolines	2022
Letermovir conversion after valganciclovir treatment in cytomegalovirus high-risk abdominal solid organ transplant recipients may promote development of cytomegalovirus-specific cell mediated immunity. Transplant infectious disease : an official journal of the Transplantation Society, 2022, Volume: 24, Issue:1 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Ganciclovir; Humans; Immunity, Cellular; Kidney Transplantation; Male; Quinazolines; Transplant Recipients; Valganciclovir	2022
Impact of Letermovir Primary Cytomegalovirus Prophylaxis on 1-Year Mortality After Allogeneic Hematopoietic Cell Transplantation: A Retrospective Cohort Study. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022, 09-14, Volume: 75, Issue:5 Topics: Acetates; Adult; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Hematopoietic Stem Cell Transplantation; Humans; Quinazolines; Retrospective Studies	2022
Letermovir and maribavir for pan-resistant cytomegalovirus infection in a patient with haematologic malignancy: Consideration for combination therapy. Journal of clinical pharmacy and therapeutics, 2022, Volume: 47, Issue:5 Topics: Acetates; Adult; Antiviral Agents; Benzimidazoles; Cytomegalovirus; Cytomegalovirus Infections; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Male; Quinazolines; Ribonucleosides	2022
Cytomegalovirus prevention in thoracic organ transplantation: A single-center evaluation of letermovir prophylaxis. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2022, Volume: 41, Issue:4 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Hematopoietic Stem Cell Transplantation; Humans; Organ Transplantation; Quinazolines; Retrospective Studies; Transplant Recipients	2022
Human Cytomegalovirus-Specific T-Cell Reconstitution and Late-Onset Cytomegalovirus Infection in Hematopoietic Stem Cell Transplantation Recipients following Letermovir Prophylaxis. Transplantation and cellular therapy, 2022, Volume: 28, Issue:4 Topics: Acetates; Cytomegalovirus; Cytomegalovirus Infections; Hematopoietic Stem Cell Transplantation; Humans; Neoplasm Recurrence, Local; Prospective Studies; Quinazolines	2022
Effective Letermovir Prophylaxis of CMV infection post allogeneic hematopoietic cell transplantation: Results from the French temporary authorization of use compassionate program. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2022, Volume: 148 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Hematopoietic Stem Cell Transplantation; Humans; Middle Aged; Quinazolines	2022
Letermovir vs. high-dose valacyclovir for cytomegalovirus prophylaxis following haploidentical or mismatched unrelated donor allogeneic hematopoietic cell transplantation receiving post-transplant cyclophosphamide. Leukemia & lymphoma, 2022, Volume: 63, Issue:8 Topics: Acetates; Adult; Cyclophosphamide; Cytomegalovirus; Cytomegalovirus Infections; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Quinazolines; Retrospective Studies; Unrelated Donors; Valacyclovir	2022
Letermovir for cytomegalovirus primary prophylaxis in a multiple abdominal/small bowel transplant recipient. Clinical transplantation, 2022, Volume: 36, Issue:5 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Hematopoietic Stem Cell Transplantation; Humans; Quinazolines; Transplant Recipients	2022
Letermovir prophylaxis for cytomegalovirus reactivation in children who underwent hematopoietic stem cell transplantation: A single-institute experience in Taiwan. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2022, Volume: 55, Issue:2 Topics: Acetates; Antiviral Agents; Child; Cytomegalovirus; Hematopoietic Stem Cell Transplantation; Humans; Quinazolines; Taiwan	2022
Reliable quantification of Cytomegalovirus DNAemia in Letermovir treated patients. Antiviral research, 2022, Volume: 201 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Deoxyribonucleases; DNA, Viral; Ganciclovir; Humans; Quinazolines	2022
Letermovir for Cytomegalovirus Prevention in Adolescent Patients Following Hematopoietic Cell Transplantation. Journal of the Pediatric Infectious Diseases Society, 2022, Jul-21, Volume: 11, Issue:7 Topics: Acetates; Adolescent; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Hematopoietic Stem Cell Transplantation; Humans; Quinazolines	2022
In vitro activity of letermovir against human cytomegalovirus isolates with different drug susceptibility phenotypes. Antiviral research, 2022, Volume: 202 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Viral; Ganciclovir; Humans; Mutation; Phenotype; Quinazolines	2022
Letermovir Discontinuation at Day 100 After Allogeneic Stem Cell Transplant Is Associated With Increased CMV-Related Mortality. Transplantation and cellular therapy, 2022, Volume: 28, Issue:8 Topics: Acetates; Cytomegalovirus; Cytomegalovirus Infections; Hematopoietic Stem Cell Transplantation; Humans; Immunoglobulin G; Quinazolines; Retrospective Studies; Stem Cell Transplantation; Transplantation, Homologous	2022
First clinical description of letermovir resistance mutation in cytomegalovirus UL51 gene and potential impact on the terminase complex structure. Antiviral research, 2022, Volume: 204 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Drug Resistance, Viral; Endodeoxyribonucleases; Humans; Mutation; Quinazolines; Viral Proteins	2022
Real-world efficacy of letermovir prophylaxis for cytomegalovirus infection after allogeneic hematopoietic stem cell transplantation: A single-center retrospective analysis. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2022, Volume: 28, Issue:9 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Hematopoietic Stem Cell Transplantation; Humans; Quinazolines; Retrospective Studies	2022
Relative frequency of cytomegalovirus UL56 gene mutations detected in genotypic letermovir resistance testing. Antiviral research, 2022, Volume: 207 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Viral; Humans; Mutation; Quinazolines	2022
Cytomegalovirus breakthrough and resistance during letermovir prophylaxis. Bone marrow transplantation, 2023, Volume: 58, Issue:4 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Hematopoietic Stem Cell Transplantation; Humans; Quinazolines	2023
Thioxothiazolo[3,4-a]quinazoline derivatives inhibit the human cytomegalovirus alkaline nuclease. Antiviral research, 2023, Volume: 217 Topics: Animals; Antiviral Agents; Cytomegalovirus; DNA Replication; DNA, Viral; Herpesviridae; Humans; Mice; Quinazolines; Simplexvirus; Virus Replication	2023
Letermovir vs Valganciclovir for Cytomegalovirus Prophylaxis After Kidney Transplant-Reply. JAMA, 2023, 11-14, Volume: 330, Issue:18 Topics: Acetates; Antiviral Agents; Chemoprevention; Cytomegalovirus; Cytomegalovirus Infections; Kidney Transplantation; Quinazolines; Valganciclovir	2023
Letermovir vs Valganciclovir for Cytomegalovirus Prophylaxis After Kidney Transplant. JAMA, 2023, 11-14, Volume: 330, Issue:18 Topics: Acetates; Antiviral Agents; Chemoprevention; Cytomegalovirus; Kidney Transplantation; Quinazolines; Valganciclovir	2023
Single-center experience with use of letermovir for CMV prophylaxis or treatment in thoracic organ transplant recipients. Transplant infectious disease : an official journal of the Transplantation Society, 2019, Volume: 21, Issue:6 Topics: Acetates; Adult; Aged; Antibiotic Prophylaxis; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; DNA, Viral; Female; Graft Rejection; Heart Transplantation; Humans; Immunosuppressive Agents; Lung Transplantation; Male; Middle Aged; Quinazolines; Secondary Prevention; Transplant Recipients; Treatment Outcome	2019
Letermovir for primary and secondary cytomegalovirus prevention in allogeneic hematopoietic cell transplant recipients: Real-world experience. Transplant infectious disease : an official journal of the Transplantation Society, 2019, Volume: 21, Issue:6 Topics: Acetates; Adult; Aged; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Quinazolines; Retrospective Studies; Secondary Prevention; Transplantation, Homologous; Treatment Outcome; Viral Load; Virus Activation; Young Adult	2019
Letermovir for the Management of Cytomegalovirus-associated Uveitis. Ocular immunology and inflammation, 2021, Jan-02, Volume: 29, Issue:1 Topics: Acetates; Adult; Aged; Antiviral Agents; Aqueous Humor; Cytomegalovirus; Cytomegalovirus Infections; DNA, Viral; Eye Infections, Viral; Female; Follow-Up Studies; Humans; Male; Middle Aged; Quinazolines; Retrospective Studies; Uveitis; Visual Acuity	2021
Artemisone demonstrates synergistic antiviral activity in combination with approved and experimental drugs active against human cytomegalovirus. Antiviral research, 2019, Volume: 172 Topics: Acetates; Antiviral Agents; Artemisinins; Benzimidazoles; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Interactions; Drug Synergism; Drugs, Investigational; Female; Ganciclovir; Humans; Organ Culture Techniques; Organophosphonates; Placenta; Pregnancy; Quinazolines; Ribonucleosides	2019
Highlighting of a LAGLIDADG and a Zing Finger Motifs Located in the pUL56 Sequence Crucial for HCMV Replication. Viruses, 2019, 11-26, Volume: 11, Issue:12 Topics: Acetates; Amino Acid Sequence; Antiviral Agents; Cytomegalovirus; DNA Packaging; Drug Resistance, Viral; Endodeoxyribonucleases; Humans; Protein Domains; Quinazolines; Sequence Alignment; Viral Structural Proteins; Virus Replication; Zinc Fingers	2019
Letermovir Resistance Analysis in a Clinical Trial of Cytomegalovirus Prophylaxis for Hematopoietic Stem Cell Transplant Recipients. The Journal of infectious diseases, 2020, 03-16, Volume: 221, Issue:7 Topics: Acetates; Antibiotic Prophylaxis; Antiviral Agents; Clinical Trials, Phase III as Topic; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Viral; Hematopoietic Stem Cell Transplantation; Humans; Mutation; Quinazolines; Randomized Controlled Trials as Topic	2020
Letermovir Resistance in Hematopoietic Stem Cell Transplant Recipients: The Risks Associated with Cytomegalovirus Prophylaxis. The Journal of infectious diseases, 2020, 03-16, Volume: 221, Issue:7 Topics: Acetates; Cytomegalovirus; Hematopoietic Stem Cell Transplantation; Quinazolines	2020
De Novo Genotypic Heterogeneity in the UL56 Region in Cytomegalovirus-Infected Tissues: Implications for Primary Letermovir Resistance. The Journal of infectious diseases, 2020, 04-07, Volume: 221, Issue:9 Topics: Acetates; Aged; Aged, 80 and over; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Viral; Endodeoxyribonucleases; Female; Genetic Heterogeneity; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Mutation; Open Reading Frames; Quinazolines; Viral Structural Proteins	2020
Letermovir (Prevymis) for CMV prophylaxis. The Medical letter on drugs and therapeutics, 2019, Dec-16, Volume: 61, Issue:1587 Topics: Acetates; Adult; Allografts; Antiviral Agents; Clinical Trials as Topic; Cytomegalovirus; Cytomegalovirus Infections; Hematopoietic Stem Cell Transplantation; Humans; Quinazolines; Transplant Recipients	2019
Letermovir as Salvage Therapy for Cytomegalovirus Infection in Transplant Recipients. Transplantation, 2020, Volume: 104, Issue:2 Topics: Acetates; Adult; Aged; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Organ Transplantation; Quinazolines; Retrospective Studies; Salvage Therapy; Transplant Recipients; Viral Load	2020
Clinical "real-world" experience with letermovir for prevention of cytomegalovirus infection in allogeneic hematopoietic cell transplant recipients. Clinical transplantation, 2020, Volume: 34, Issue:7 Topics: Acetates; Adult; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Hematopoietic Stem Cell Transplantation; Humans; Quinazolines; Transplant Recipients	2020
Letermovir breakthroughs during the French Named Patient Programme: interest of monitoring blood concentration in clinical practice. The Journal of antimicrobial chemotherapy, 2020, 08-01, Volume: 75, Issue:8 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Humans; Quinazolines	2020
Letermovir Prophylaxis Decreases Burden of Cytomegalovirus (CMV) in Patients at High Risk for CMV Disease Following Hematopoietic Cell Transplant. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2020, Volume: 26, Issue:10 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Hematopoietic Stem Cell Transplantation; Humans; Quinazolines; Retrospective Studies; Transplant Recipients	2020
Combination Treatment With Letermovir and Ganciclovir for Maintenance Therapy of Multidrug-resistant CMV Infection in a Liver Transplant Recipient. Transplantation, 2020, Volume: 104, Issue:8 Topics: Acetates; Allografts; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Humans; Liver; Liver Transplantation; Maintenance Chemotherapy; Off-Label Use; Postoperative Care; Quinazolines; Treatment Outcome; Valganciclovir	2020
Cost-effectiveness analysis of cytomegalovirus prophylaxis in allogeneic hematopoietic cell transplant recipients from a US payer perspective. Journal of medical virology, 2021, Volume: 93, Issue:6 Topics: Acetates; Antiviral Agents; Clinical Trials as Topic; Cost-Benefit Analysis; Cytomegalovirus; Cytomegalovirus Infections; Hematopoietic Stem Cell Transplantation; Humans; Quinazolines; Transplant Recipients; United States	2021
Letermovir for the compassionate therapeutic use of cytomegalovirus infection. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2021, Volume: 40, Issue:2 Topics: Acetates; Aged; Antiviral Agents; Compassionate Use Trials; Cytomegalovirus; Cytomegalovirus Infections; Female; Humans; Male; Middle Aged; Quinazolines; Retrospective Studies; Treatment Outcome	2021
Incidence of CMV Replication and the Role of Letermovir Primary/Secondary Prophylaxis in the Early Phase After Allogeneic Hematopoietic Stem Cell Transplantation - A Single Centre Study. Anticancer research, 2020, Volume: 40, Issue:10 Topics: Acetates; Adult; Aged; Cytomegalovirus; Cytomegalovirus Infections; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Quinazolines; Transplantation, Homologous; Virus Replication	2020
Extended letermovir administration, beyond day 100, is effective for CMV prophylaxis in patients with graft versus host disease. Transplant infectious disease : an official journal of the Transplantation Society, 2021, Volume: 23, Issue:2 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Quinazolines; Retrospective Studies	2021
Letermovir for Prevention of Cytomegalovirus Reactivation in Haploidentical and Mismatched Adult Donor Allogeneic Hematopoietic Cell Transplantation with Post-Transplantation Cyclophosphamide for Graft-versus-Host Disease Prophylaxis. Transplantation and cellular therapy, 2021, Volume: 27, Issue:1 Topics: Acetates; Adult; Cyclophosphamide; Cytomegalovirus; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Quinazolines	2021
Efficacy of prophylactic letermovir for cytomegalovirus reactivation in hematopoietic cell transplantation: a multicenter real-world data. Bone marrow transplantation, 2021, Volume: 56, Issue:4 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Hematopoietic Stem Cell Transplantation; Humans; Quinazolines; Retrospective Studies	2021
Cost-effectiveness of letermovir as cytomegalovirus prophylaxis in adult recipients of allogeneic hematopoietic stem cell transplantation in Hong Kong. Journal of medical economics, 2020, Volume: 23, Issue:12 Topics: Acetates; Adult; Antiviral Agents; Cost-Benefit Analysis; Cytomegalovirus; Hematopoietic Stem Cell Transplantation; Hong Kong; Humans; Quinazolines	2020
Emergence of letermovir resistance in solid organ transplant recipients with ganciclovir resistant cytomegalovirus infection: A case series and review of the literature. Transplant infectious disease : an official journal of the Transplantation Society, 2021, Volume: 23, Issue:3 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Viral; Ganciclovir; Humans; Organ Transplantation; Quinazolines; Transplant Recipients	2021
Letermovir prophylaxis is effective in preventing cytomegalovirus reactivation after allogeneic hematopoietic cell transplantation: single-center real-world data. Annals of hematology, 2021, Volume: 100, Issue:8 Topics: Acetates; Adult; Aged; Antiviral Agents; Cohort Studies; Cytomegalovirus; Cytomegalovirus Infections; Female; Hematopoietic Stem Cell Transplantation; Humans; Latent Infection; Male; Middle Aged; Quinazolines; Transplantation, Homologous; Virus Activation; Young Adult	2021
Use of letermovir in off-label indications: Infectious Diseases Working Party of European Society of Blood and Marrow Transplantation retrospective study. Bone marrow transplantation, 2021, Volume: 56, Issue:5 Topics: Acetates; Adult; Antiviral Agents; Bone Marrow; Child; Communicable Diseases; Cytomegalovirus; Hematopoietic Stem Cell Transplantation; Humans; Off-Label Use; Quinazolines; Retrospective Studies	2021
Positive HCMV DNAemia in stem cell recipients undergoing letermovir prophylaxis is expression of abortive infection. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2021, Volume: 21, Issue:4 Topics: Acetates; Antiviral Agents; Cytomegalovirus; DNA, Viral; Prospective Studies; Quinazolines; Stem Cells	2021
Letermovir prophylaxis in solid organ transplant-Assessing CMV breakthrough and tacrolimus drug interaction. Transplant infectious disease : an official journal of the Transplantation Society, 2021, Volume: 23, Issue:4 Topics: Acetates; Antiviral Agents; Cohort Studies; Cytomegalovirus; Cytomegalovirus Infections; Drug Interactions; Humans; Organ Transplantation; Quinazolines; Tacrolimus	2021
Absorption, Metabolism, Distribution, and Excretion of Letermovir. Current drug metabolism, 2021, Volume: 22, Issue:10 Topics: Acetates; Adult; Animals; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Biotransformation; Cytochrome P-450 CYP3A; Cytomegalovirus; Cytomegalovirus Infections; Drug Elimination Routes; Drug Interactions; Glucuronosyltransferase; Healthy Volunteers; Hematopoietic Stem Cell Transplantation; Humans; Male; Medication Therapy Management; Neoplasm Proteins; Organic Anion Transporters; Quinazolines; Rats; Tissue Distribution	2021
Cytomegalovirus-specific T-cell reconstitution following letermovir prophylaxis after hematopoietic cell transplantation. Blood, 2021, 07-08, Volume: 138, Issue:1 Topics: Acetates; Adult; Aged; Cytomegalovirus; Cytomegalovirus Infections; Disease-Free Survival; Female; Hematopoietic Stem Cell Transplantation; Humans; Linear Models; Lymphocyte Count; Male; Middle Aged; Multivariate Analysis; Phenotype; Quinazolines; T-Lymphocytes; Virus Activation; Young Adult	2021
Prophylactic letermovir decreases cytomegalovirus reactivation after stem cell transplantation: a single-center real-world evidence study. Le infezioni in medicina, 2021, Mar-01, Volume: 29, Issue:1 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Hematopoietic Stem Cell Transplantation; Humans; Quinazolines; Transplant Recipients; Transplantation, Homologous	2021
Successful Treatment of UL97 Mutation Ganciclovir-Resistant Cytomegalovirus Viremia in a Renal Transplant Recipient With Letermovir and Adjunct Hyperimmune Cytomegalovirus Immunoglobulin: A Case Report. Transplantation proceedings, 2021, Volume: 53, Issue:4 Topics: Acetates; Antibodies, Viral; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Viral; Ganciclovir; Humans; Immunoglobulins, Intravenous; Kidney Transplantation; Male; Middle Aged; Mutation; Postoperative Complications; Quinazolines; Viral Load; Viremia	2021
Refractory and Resistant Cytomegalovirus After Hematopoietic Cell Transplant in the Letermovir Primary Prophylaxis Era. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021, 10-20, Volume: 73, Issue:8 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Hematopoietic Stem Cell Transplantation; Humans; Quinazolines; Retrospective Studies; Transplant Recipients	2021
Cytomegalovirus events in high-risk allogeneic hematopoietic-cell transplantation patients who received letermovir prophylaxis. Transplant infectious disease : an official journal of the Transplantation Society, 2021, Volume: 23, Issue:4 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Hematopoietic Stem Cell Transplantation; Humans; Quinazolines; Retrospective Studies	2021
Predictors of breakthrough clinically significant cytomegalovirus infection during letermovir prophylaxis in high-risk hematopoietic cell transplant recipients. Immunity, inflammation and disease, 2021, Volume: 9, Issue:3 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Hematopoietic Stem Cell Transplantation; Humans; Quinazolines; Retrospective Studies; Transplant Recipients	2021
Letermovir in lung transplant recipients with cytomegalovirus infection: A retrospective observational study. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2021, Volume: 21, Issue:10 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Viral; Hematopoietic Stem Cell Transplantation; Humans; Lung; Quinazolines; Retrospective Studies; Transplant Recipients	2021
Use of letermovir-valganciclovir combination as a step-down treatment after foscarnet for ganciclovir-resistant CMV infection in kidney transplant recipients. Clinical transplantation, 2021, Volume: 35, Issue:11 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Foscarnet; Ganciclovir; Humans; Kidney Transplantation; Quinazolines; Transplant Recipients; Valganciclovir	2021
Letermovir and HCT: too much of a good thing? Blood, 2021, 07-08, Volume: 138, Issue:1 Topics: Acetates; Cytomegalovirus; Cytomegalovirus Infections; Humans; Quinazolines	2021
The addition of adjunctive letermovir to valganciclovir for refractory cytomegalovirus viremia in kidney transplant recipients. Transplant infectious disease : an official journal of the Transplantation Society, 2021, Volume: 23, Issue:4 Topics: Acetates; Adult; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Ganciclovir; Humans; Kidney Transplantation; Quinazolines; Transplant Recipients; Valganciclovir; Viremia	2021
New Insights into Human Cytomegalovirus pUL52 Structure. Viruses, 2021, 08-18, Volume: 13, Issue:8 Topics: Acetates; Amino Acid Motifs; Antiviral Agents; Conserved Sequence; Cytomegalovirus; Cytomegalovirus Infections; Endodeoxyribonucleases; Humans; Quinazolines; Viral Proteins; Virus Replication	2021
Comparison of Cytomegalovirus Terminase Gene Mutations Selected after Exposure to Three Distinct Inhibitor Compounds. Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:11 Topics: Acetates; Antiviral Agents; Benzimidazoles; Cytomegalovirus; Drug Resistance, Viral; Endodeoxyribonucleases; Humans; Microbial Sensitivity Tests; Mutation; Naphthalenesulfonates; Quinazolines; Ribonucleosides; Viral Proteins; Viral Structural Proteins	2017
A third component of the human cytomegalovirus terminase complex is involved in letermovir resistance. Antiviral research, 2017, Volume: 148 Topics: Acetates; Antiviral Agents; Cells, Cultured; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Viral; Endodeoxyribonucleases; Fibroblasts; Genes, Viral; Humans; Multiprotein Complexes; Mutation; Quinazolines; Viral Proteins	2017
Human Cytomegalovirus Replication Is Inhibited by the Autophagy-Inducing Compounds Trehalose and SMER28 through Distinctively Different Mechanisms. Journal of virology, 2018, 03-15, Volume: 92, Issue:6 Topics: Allyl Compounds; Antiviral Agents; Autophagy; Cell Line; Cytomegalovirus; Cytomegalovirus Infections; Humans; Quinazolines; rab GTP-Binding Proteins; rab7 GTP-Binding Proteins; Trehalose; Virus Replication	2018
Letermovir Prophylaxis for Cytomegalovirus. The New England journal of medicine, 2018, 03-08, Volume: 378, Issue:10 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Ganciclovir; Humans; Quinazolines	2018
Letermovir Prophylaxis for Cytomegalovirus. The New England journal of medicine, 2018, 03-08, Volume: 378, Issue:10 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Ganciclovir; Humans; Quinazolines	2018
Letermovir Prophylaxis for Cytomegalovirus. The New England journal of medicine, 2018, 03-08, Volume: 378, Issue:10 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Ganciclovir; Humans; Quinazolines	2018
Letermovir Prophylaxis for Cytomegalovirus. The New England journal of medicine, 2018, 03-08, Volume: 378, Issue:10 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Ganciclovir; Humans; Quinazolines	2018
New Locus of Drug Resistance in the Human Cytomegalovirus UL56 Gene Revealed by Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:9 Topics: Acetates; Amino Acid Substitution; Antiviral Agents; Cell Line; Cytomegalovirus; Cytomegalovirus Infections; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Endodeoxyribonucleases; Ganciclovir; Humans; Mutation; Quinazolines; Viral Structural Proteins	2018
Letermovir successfully used for secondary prophylaxis in a heart transplant recipient with ganciclovir-resistant cytomegalovirus syndrome (UL97 mutation). Transplant infectious disease : an official journal of the Transplantation Society, 2018, Volume: 20, Issue:5 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Viral; Ganciclovir; Heart Transplantation; Humans; Male; Middle Aged; Mutation; Phosphotransferases (Alcohol Group Acceptor); Quinazolines; Secondary Prevention; Treatment Outcome	2018
Evodiamine alleviates severe pneumonia induced by methicillin-susceptible Staphylococcus aureus following cytomegalovirus reactivation through suppressing NF-κB and MAPKs. International journal of molecular medicine, 2018, Volume: 42, Issue:6 Topics: Animals; Blotting, Western; Cell Line; Cytomegalovirus; Female; Humans; Interleukin-1beta; Interleukin-6; Methicillin; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; NF-kappa B; Pneumonia; Quinazolines; Signal Transduction; Staphylococcus aureus; Tumor Necrosis Factor-alpha	2018
Breakthrough cytomegalovirus pneumonia in hematopoietic stem cell transplant recipient on letermovir prophylaxis. Bone marrow transplantation, 2019, Volume: 54, Issue:6 Topics: Acetates; Cytomegalovirus; Female; Hematopoietic Stem Cell Transplantation; Humans; Middle Aged; Pneumonia; Quinazolines; Transplantation Conditioning	2019
Use of Letermovir as Salvage Therapy for Drug-Resistant Cytomegalovirus Retinitis. Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:3 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Retinitis; Drug Resistance, Viral; Ganciclovir; Humans; Organ Transplantation; Quinazolines; Salvage Therapy; Transplant Recipients	2019
Letermovir for prophylaxis of cytomegalovirus manifestations in adult allogeneic hematopoietic stem cell transplant recipients. Future microbiology, 2019, Volume: 14 Topics: Acetates; Adult; Antibiotic Prophylaxis; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Drug Evaluation; Drug Interactions; Drug Resistance, Viral; Endodeoxyribonucleases; Hematopoietic Stem Cell Transplantation; Humans; Nucleic Acid Synthesis Inhibitors; Quinazolines; Transplant Recipients; Treatment Outcome	2019
Caution Is Required before Recommending Wide Use of Letermovir as Salvage Therapy for Cytomegalovirus Diseases. Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:5 Topics: Acetates; Cytomegalovirus; Cytomegalovirus Retinitis; Humans; Quinazolines; Salvage Therapy	2019
Reply to Frange and Leruez-Ville, "Caution Is Required before Recommending Wide Use of Letermovir as Salvage Therapy for Cytomegalovirus Diseases". Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:5 Topics: Acetates; Cytomegalovirus; Cytomegalovirus Retinitis; Humans; Quinazolines; Salvage Therapy	2019
Fast breakthrough of resistant cytomegalovirus during secondary letermovir prophylaxis in a hematopoietic stem cell transplant recipient. BMC infectious diseases, 2019, May-08, Volume: 19, Issue:1 Topics: Acetates; Adult; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Hematopoietic Stem Cell Transplantation; Humans; Male; Mutation; Quinazolines; Secondary Prevention; Valganciclovir; Viral Load; Viral Proteins; Viral Structural Proteins	2019
Cytomegalovirus Viremia and Death After Hematopoietic Cell Transplantation: More Complex Than "To Have and Have Not"? Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020, 04-10, Volume: 70, Issue:8 Topics: Acetates; Cytomegalovirus; Cytomegalovirus Infections; Hematopoietic Stem Cell Transplantation; Humans; Quinazolines; Viremia	2020
Compassionate Use of Letermovir in a 2-Year-Old Immunocompromised Child With Resistant Cytomegalovirus Disease. Journal of the Pediatric Infectious Diseases Society, 2020, Feb-28, Volume: 9, Issue:1 Topics: Acetates; Antiviral Agents; Child, Preschool; Compassionate Use Trials; Cytomegalovirus; Cytomegalovirus Infections; DNA, Viral; Dose-Response Relationship, Drug; Drug Monitoring; Extracorporeal Membrane Oxygenation; Fatal Outcome; Female; Ganciclovir; Hepatitis, Viral, Human; Humans; Immunocompromised Host; Opportunistic Infections; Pneumonia, Viral; Polymerase Chain Reaction; Quinazolines; Treatment Failure; Viral Load	2020
Letermovir for Difficult to Treat Cytomegalovirus Infection in Lung Transplant Recipients. Transplantation, 2020, Volume: 104, Issue:2 Topics: Acetates; Adult; Aged; Antibodies, Viral; Cytomegalovirus; Cytomegalovirus Infections; Female; Graft Rejection; Humans; Lung Transplantation; Male; Middle Aged; Quinazolines; Transplant Recipients	2020
Geno- and phenotypic characterization of human cytomegalovirus mutants selected in vitro after letermovir (AIC246) exposure. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:1 Topics: Acetates; Antiviral Agents; Cytomegalovirus; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Humans; Quinazolines	2014
CMV-induced pathology: pathway and gene-gene interaction analysis. Experimental and molecular pathology, 2014, Volume: 97, Issue:1 Topics: Animals; Carcinoma, Mucoepidermoid; Cytomegalovirus; Cytomegalovirus Infections; Epistasis, Genetic; Female; Gefitinib; Gene Expression Regulation; Gene Regulatory Networks; Humans; Mice; Mice, Inbred C57BL; Models, Theoretical; Organ Culture Techniques; Protein Kinase Inhibitors; Quinazolines; Salivary Gland Neoplasms; Salivary Glands; Signal Transduction; Tumor Microenvironment	2014
Phenotypic characterization of two naturally occurring human Cytomegalovirus sequence polymorphisms located in a distinct region of ORF UL56 known to be involved in in vitro resistance to letermovir. Antiviral research, 2015, Volume: 116 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Viral; Genotype; Hematopoietic Stem Cell Transplantation; Humans; Mutation; Open Reading Frames; Phenotype; Polymorphism, Genetic; Quinazolines; Viral Structural Proteins	2015
In vitro drug combination studies of Letermovir (AIC246, MK-8228) with approved anti-human cytomegalovirus (HCMV) and anti-HIV compounds in inhibition of HCMV and HIV replication. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:6 Topics: Acetates; Anti-HIV Agents; Antiviral Agents; Cell Line; Cytomegalovirus; Drug Combinations; Drug Resistance, Viral; Humans; Quinazolines; Virus Replication	2015
Rapid In Vitro Evolution of Human Cytomegalovirus UL56 Mutations That Confer Letermovir Resistance. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:10 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Humans; Mutation; Quinazolines; Virus Replication	2015
Impact of glycoprotein B genotype and naturally occurring ORF UL56 polymorphisms upon susceptibility of clinical human cytomegalovirus isolates to letermovir. Antiviral research, 2016, Volume: 132 Topics: Acetates; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Viral; Ganciclovir; Genotype; Humans; Microbial Sensitivity Tests; Mutation; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Quinazolines; Viral Envelope Proteins; Viral Structural Proteins	2016
The chemical class of quinazoline compounds provides a core structure for the design of anticytomegaloviral kinase inhibitors. Antiviral research, 2016, Volume: 134 Topics: Antiviral Agents; Cells, Cultured; Cytomegalovirus; Drug Design; Drug Resistance, Viral; Female; Fibroblasts; Humans; Models, Molecular; Molecular Docking Simulation; Placenta; Pregnancy; Protein Kinase Inhibitors; Quinazolines; Viral Proteins; Virus Replication	2016
Potent Inhibition of Human Cytomegalovirus by Modulation of Cellular SNARE Syntaxin 5. Journal of virology, 2017, Jan-01, Volume: 91, Issue:1 Topics: Animals; Cell Line; Cell Membrane; Cytomegalovirus; Cytoplasm; Epithelial Cells; Fibroblasts; Gene Expression Regulation; Genes, Reporter; Green Fluorescent Proteins; Host-Pathogen Interactions; Humans; Luminescent Proteins; Mice; Protein Transport; Qa-SNARE Proteins; Quinazolines; Red Fluorescent Protein; Signal Transduction; Virion; Virus Assembly	2017
Synthesis and characterization of novel quinazoline type inhibitors for mutant and wild-type EGFR and RICK kinases. Journal of receptor and signal transduction research, 2008, Volume: 28, Issue:4 Topics: Cytomegalovirus; ErbB Receptors; Humans; Mutant Proteins; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase Inhibitors; Quinazolines; Receptor-Interacting Protein Serine-Threonine Kinase 2; Viral Proteins	2008
In vitro and in vivo activities of the novel anticytomegalovirus compound AIC246. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:3 Topics: Acetic Acid; Animals; Antiviral Agents; Cell Line; Cells, Cultured; Cytomegalovirus; Cytomegalovirus Infections; Cytopathogenic Effect, Viral; Dermis; Disease Models, Animal; Fibroblasts; Humans; Lung; Mice; Mice, SCID; Quinazolines; Transplantation, Heterologous; Treatment Outcome; Virus Replication	2010
In vitro evaluation of the activities of the novel anticytomegalovirus compound AIC246 (letermovir) against herpesviruses and other human pathogenic viruses. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:2 Topics: Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Viral; Herpesviridae; Humans; Microbial Sensitivity Tests; Quinazolines; Species Specificity; Virus Diseases; Viruses	2012
Benzothiadiazine dioxide human cytomegalovirus inhibitors: synthesis and antiviral evaluation of main heterocycle modified derivatives. Antiviral chemistry & chemotherapy, 2003, Volume: 14, Issue:2 Topics: Antiviral Agents; Benzothiadiazines; Cell Division; Cell Line; Cytomegalovirus; Fibroblasts; Humans; Inhibitory Concentration 50; Models, Chemical; Molecular Structure; Quinazolines; Structure-Activity Relationship	2003
Novel chemical class of pUL97 protein kinase-specific inhibitors with strong anticytomegaloviral activity. Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:11 Topics: Antiviral Agents; Blotting, Western; Cell Line; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Drug Resistance, Viral; Enzyme Inhibitors; Ganciclovir; Humans; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Plasmids; Quinazolines; Viral Plaque Assay; Virus Replication	2004
Epidermal growth factor receptor is not required for human cytomegalovirus entry or signaling. Journal of virology, 2007, Volume: 81, Issue:12 Topics: Cell Fusion; Cell Line; Cytomegalovirus; Dose-Response Relationship, Drug; Enzyme Inhibitors; ErbB Receptors; Fibroblasts; Humans; Neutralization Tests; Quinazolines; Signal Transduction; Time Factors; Tyrphostins; Viral Proteins; Virus Internalization	2007
Protein kinase inhibitors of the quinazoline class exert anti-cytomegaloviral activity in vitro and in vivo. Antiviral research, 2008, Volume: 79, Issue:1 Topics: Animals; Antiviral Agents; Cell Survival; Cells, Cultured; Cytomegalovirus; Cytomegalovirus Infections; Female; Guinea Pigs; Humans; Inhibitory Concentration 50; Male; Mice; Phosphotransferases; Protein Kinase Inhibitors; Quinazolines; Rats; Sequence Deletion; Viral Load; Viral Plaque Assay; Viral Proteins	2008
The thymidylate synthase inhibitor ZD1694 potently inhibits murine and human cytomegalovirus replication in quiescent fibroblasts. Antiviral research, 2000, Volume: 47, Issue:2 Topics: Animals; Antiviral Agents; Cells, Cultured; Cytomegalovirus; DNA, Viral; Fibroblasts; Ganciclovir; Humans; Inhibitory Concentration 50; Mice; Muromegalovirus; Polymerase Chain Reaction; Quinazolines; Thiophenes; Thymidylate Synthase; Virus Replication	2000
The anticytomegaloviral activity of raltitrexed is abrogated in quiescent mouse fibroblasts that overexpress thymidylate synthase. Virus research, 2001, Volume: 73, Issue:1 Topics: Animals; Antiviral Agents; Cell Line; Cytomegalovirus; Enzyme Inhibitors; Mice; Quinazolines; Thiophenes; Thymidylate Synthase; Virus Replication	2001
FDA's newly designated treatment INDs. JAMA, 1988, Jul-08, Volume: 260, Issue:2 Topics: Clinical Protocols; Cytomegalovirus; Cytomegalovirus Infections; Drug Combinations; Drug Therapy, Combination; Glucuronates; Humans; Immune Sera; Immunoglobulins; Immunoglobulins, Intravenous; Kidney Transplantation; Leucovorin; Pneumonia, Pneumocystis; Quinazolines; Trimetrexate; United States; United States Food and Drug Administration	1988