quinazolines has been researched along with Cognitive Dysfunction in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 5 (41.67) | 2.80 |
| Authors | Studies |
|---|---|
| Bellver-Sanchis, A; Griñán-Ferré, C; Kondengaden, SM; Marsal-García, L; Pallàs, M; Turga, RC; Vázquez, S | 1 |
| Dong, YH; Huang, XF; Ke, HM; Song, GQ; Wang, JH; Xu, DF | 1 |
| An, XW; Chen, C; Chen, F; Hu, N; Jia, XL; Li, XH; Liu, R; Sun, HT; Wang, JJ; Wang, Y; Zhao, B; Zheng, CG | 1 |
| Fu, J; Li, ZY; Lu, J; Luo, XM; Wu, WY; Zhang, M; Zhao, J | 1 |
| Amin, KM; George, RF; Hegazy, GH; Ibrahim, NR; Mohamed, NM | 1 |
| Huang, G; Li, W; Liu, H; Luo, S; Lv, X; Wang, Y; Zhou, D | 1 |
| Dierkes, T; Sajikumar, S; Sharma, M | 1 |
| Chen, Y; Gavish, M; Huang, W; Liang, J; Marek, I; Ouyang, F; Singh, S; Veenman, L; Zeng, J | 1 |
| Chen, R; Hei, Y; Liu, W; Long, Q; Mao, X; Wang, J | 1 |
| Chen, JG; Li, X; Wu, YG | 1 |
| Cheng, X; Deng, G; Ding, W; Guan, H; Ju, Z; Li, S; Liu, W; Ma, C; Rong, X; Wang, C; Wang, Y; Wu, C | 1 |
| Gao, DP; Gao, R; Ji, MH; Shen, JC; Yang, JJ; Yang, RH; Zhang, SG | 1 |
12 other study(ies) available for quinazolines and Cognitive Dysfunction
| Article | Year |
|---|---|
Pharmacological inhibition of G9a/GLP restores cognition and reduces oxidative stress, neuroinflammation and β-Amyloid plaques in an early-onset Alzheimer's disease mouse model.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognition; Cognitive Dysfunction; Gene Expression Regulation; Glucagon-Like Peptides; Hippocampus; Histone-Lysine N-Methyltransferase; Histones; Inflammation; Male; Mice; NF-E2-Related Factor 2; Oxidative Stress; Quinazolines | 2019 |
Novel PDE5 inhibitors derived from rutaecarpine for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Cholinergic Antagonists; Cognitive Dysfunction; Cyclic Nucleotide Phosphodiesterases, Type 5; Dose-Response Relationship, Drug; Indole Alkaloids; Mice; Models, Molecular; Molecular Structure; Morris Water Maze Test; Phosphodiesterase 5 Inhibitors; Protein Conformation; Quinazolines; Scopolamine | 2020 |
Rutaecarpine Ameliorated High Sucrose-Induced Alzheimer's Disease Like Pathological and Cognitive Impairments in Mice.
Topics: Alzheimer Disease; Animals; Cognitive Dysfunction; Glycogen Synthase Kinase 3 beta; Indole Alkaloids; Mice; Phosphorylation; Quinazolines; Sucrose | 2021 |
Post-status epilepticus treatment with the Fyn inhibitor, saracatinib, improves cognitive function in mice.
Topics: Animals; Benzodioxoles; Cognition; Cognitive Dysfunction; Enzyme Inhibitors; Hippocampus; Male; Mice; Mice, Inbred C57BL; Neurons; Proto-Oncogene Proteins c-fyn; Quinazolines; Status Epilepticus | 2021 |
Design, synthesis, and pharmacological characterization of some 2-substituted-3-phenyl-quinazolin-4(3H)-one derivatives as phosphodiesterase inhibitors.
Topics: Animals; Behavior, Animal; Blood-Brain Barrier; Cognitive Dysfunction; Disease Models, Animal; Inhibitory Concentration 50; Mice; Molecular Docking Simulation; Phosphodiesterase Inhibitors; Quinazolines; Scopolamine; Structure-Activity Relationship; Sulfides | 2021 |
Folic acid alleviates age-related cognitive decline and inhibits apoptosis of neurocytes in senescence-accelerated mouse prone 8: deoxythymidine triphosphate biosynthesis as a potential mechanism.
Topics: Aging; Animals; Apoptosis; Brain; Cognitive Dysfunction; Dietary Supplements; Folic Acid; Male; Memory; Mice; Morris Water Maze Test; Neurons; Quinazolines; Telomere Shortening; Thiophenes; Thymidylate Synthase; Thymine Nucleotides; Uracil | 2021 |
Epigenetic regulation by G9a/GLP complex ameliorates amyloid-beta 1-42 induced deficits in long-term plasticity and synaptic tagging/capture in hippocampal pyramidal neurons.
Topics: Amyloid beta-Peptides; Animals; Azepines; Brain-Derived Neurotrophic Factor; CA1 Region, Hippocampal; Cognitive Dysfunction; Epigenesis, Genetic; Histone-Lysine N-Methyltransferase; Long-Term Potentiation; Male; Microtomy; Peptide Fragments; Pyramidal Cells; Quinazolines; Rats; Rats, Wistar; Receptor, trkB; Synapses; Tissue Culture Techniques | 2017 |
2-Cl-MGV-1 Ameliorates Apoptosis in the Thalamus and Hippocampus and Cognitive Deficits After Cortical Infarct in Rats.
Topics: Animals; Apoptosis; Carbamates; Cerebral Infarction; Cognitive Dysfunction; Hippocampus; Male; Maze Learning; Membrane Potential, Mitochondrial; Memory; Mitochondria; Neuroglia; Neurons; Neuroprotective Agents; Quinazolines; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptors, GABA; Thalamus | 2017 |
Neuregulin1 attenuates cognitive deficits and hippocampal CA1 neuronal apoptosis partly via ErbB4 receptor in a rat model of chronic cerebral hypoperfusion.
Topics: Animals; Apoptosis; Brain Ischemia; Cognition; Cognition Disorders; Cognitive Dysfunction; Disease Models, Animal; Hippocampus; Male; Maze Learning; Memory; Neuregulin-1; Neurons; Neuroprotective Agents; Quinazolines; Rats; Rats, Sprague-Dawley; Receptor, ErbB-4; Spatial Learning; Temporal Lobe; Tyrphostins | 2019 |
[Effect of rutaecarpine on Alzheimer's disease-like cognitive impairments induced by high glucose in rats].
Topics: Alzheimer Disease; Animals; Cognitive Dysfunction; Glucose; Glycogen Synthase Kinase 3 beta; Indole Alkaloids; Male; Maze Learning; Phosphorylation; Quinazolines; Random Allocation; Rats; Rats, Sprague-Dawley; tau Proteins | 2019 |
Ameliorative effect of deoxyvasicine on scopolamine-induced cognitive dysfunction by restoration of cholinergic function in mice.
Topics: Acetylcholine; Alkaloids; Amnesia; Animals; Antioxidants; Brain-Derived Neurotrophic Factor; Cholinesterase Inhibitors; Cognitive Dysfunction; Hippocampus; Male; Memory; Memory Disorders; Mice, Inbred C57BL; Neurotransmitter Agents; Oxidative Stress; Peganum; Quinazolines; Scopolamine; Sesquiterpenes | 2019 |
Neuroinflammation-Induced Downregulation of Hippocampacal Neuregulin 1-ErbB4 Signaling in the Parvalbumin Interneurons Might Contribute to Cognitive Impairment in a Mouse Model of Sepsis-Associated Encephalopathy.
Topics: Animals; Cognitive Dysfunction; Disease Models, Animal; Down-Regulation; Encephalitis; Enzyme Inhibitors; Gamma Rhythm; Hippocampus; Interneurons; Mice; Neuregulin-1; Parvalbumins; Quinazolines; Receptor, ErbB-4; Sepsis-Associated Encephalopathy; Signal Transduction; Tyrphostins | 2017 |