quinazolines has been researched along with Cerebral Ischemia in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (31.25) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 5 (31.25) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Chung, JI; Jalin, AMA; Jin, S; Joung, C; Ju, C; Kim, BS; Kim, WK; Lee, KS; Lee, S; Pahk, K; Ryu, JM; Song, HY | 1 |
| Chen, Y; Han, M; Hu, L | 1 |
| Ayata, C; Danser, AHJ; de Vries, T; Ferrari, MD; Li, M; MaassenVanDenBrink, A; Mulder, IA; Qin, T; Sugimoto, K; van den Bogaerdt, A; van den Maagdenberg, AMJM; Wermer, MJH; Yanagisawa, T | 1 |
| Kuznetsova, PI; Melikyan, AL; Raskurazhev, AA; Subortseva, IN; Tanashyan, MM | 1 |
| Chen, R; Hei, Y; Liu, W; Long, Q; Mao, X; Wang, J | 1 |
| Bai, X; Chen, L; Cui, L; Wang, L; Zhang, J; Zhang, L; Zhang, X; Zhao, T; Zhao, X; Zhao, Y | 1 |
| Cheng, M; Feng, L; Hao, F; Ma, C; Pan, L; Tian, Y; Zhang, L | 1 |
| Buchan, AM; Chenard, BL; Critchett, DJ; Ganong, AH; Guanowsky, V; Menniti, FS; Seymour, PA; Welch, WM | 1 |
| Hattori, K; Ishida, J; Iwashita, A; Kamijo, K; Matsuoka, N; Matsuura, S; Mutoh, S; Tojo, N; Yamamoto, H; Yamazaki, S | 1 |
| Coppi, E; Corradetti, R; Pedata, F; Pugliese, AM; Spalluto, G | 1 |
| Kaundal, RK; Shah, KK; Sharma, SS | 1 |
| Gao, Y; Phillis, JW | 1 |
| O'Regan, MH; Perkins, LM; Phillis, JW; Simpson, RE | 1 |
| Araki, T; Hara, H; Kato, H; Kogure, K; Onodera, H | 1 |
| Hara, H; Kato, H; Kogure, K; Ozaki, A; Sukamoto, T | 1 |
| Hara, H; Kogure, K | 1 |
16 other study(ies) available for quinazolines and Cerebral Ischemia
| Article | Year |
|---|---|
The Quinazoline Otaplimastat (SP-8203) Reduces the Hemorrhagic Transformation and Mortality Aggravated after Delayed rtPA-Induced Thrombolysis in Cerebral Ischemia.
Topics: Acetamides; Animals; Brain Ischemia; Cerebral Hemorrhage; Disease Models, Animal; Endothelial Cells; Fibrinolytic Agents; Humans; Infarction, Middle Cerebral Artery; Ischemic Stroke; Male; Matrix Metalloproteinases; Quinazolines; Quinazolinones; Rats; Rats, Sprague-Dawley; Stroke; Thrombolytic Therapy; Tissue Plasminogen Activator | 2022 |
Rutaecarpine may improve neuronal injury, inhibits apoptosis, inflammation and oxidative stress by regulating the expression of ERK1/2 and Nrf2/HO-1 pathway in rats with cerebral ischemia-reperfusion injury.
Topics: Animals; Apoptosis; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Heme Oxygenase-1; Indole Alkaloids; Inflammation; Male; MAP Kinase Signaling System; Neurons; NF-E2-Related Factor 2; Oxidative Stress; Quinazolines; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2019 |
Anti-migraine Calcitonin Gene-Related Peptide Receptor Antagonists Worsen Cerebral Ischemic Outcome in Mice.
Topics: Animals; Arteries; Brain Ischemia; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Dipeptides; Humans; Mice; Piperazines; Piperidines; Pyridines; Quinazolines; Vasodilation | 2020 |
Acute ischemic stroke in the setting of essential thrombocytemia (clinical cases).
Topics: Brain Ischemia; Cerebrovascular Circulation; Female; Gene Frequency; Humans; Janus Kinase 2; Middle Aged; Platelet Aggregation Inhibitors; Platelet Count; Quinazolines; Stroke; Thrombocythemia, Essential; Treatment Outcome | 2018 |
Neuregulin1 attenuates cognitive deficits and hippocampal CA1 neuronal apoptosis partly via ErbB4 receptor in a rat model of chronic cerebral hypoperfusion.
Topics: Animals; Apoptosis; Brain Ischemia; Cognition; Cognition Disorders; Cognitive Dysfunction; Disease Models, Animal; Hippocampus; Male; Maze Learning; Memory; Neuregulin-1; Neurons; Neuroprotective Agents; Quinazolines; Rats; Rats, Sprague-Dawley; Receptor, ErbB-4; Spatial Learning; Temporal Lobe; Tyrphostins | 2019 |
Pretreatment by evodiamine is neuroprotective in cerebral ischemia: up-regulated pAkt, pGSK3β, down-regulated NF-κB expression, and ameliorated BBB permeability.
Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Capillary Permeability; Down-Regulation; Gene Expression Regulation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Male; Mice; Neuroprotective Agents; NF-kappa B; Plant Extracts; Proto-Oncogene Proteins c-akt; Quinazolines; Treatment Outcome; Up-Regulation | 2014 |
Synthesis and biological evaluation of (--)-linarinic acid derivatives as neuroprotective agents against OGD-induced cell damage.
Topics: Brain Ischemia; Cell Culture Techniques; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Culture Media; Dose-Response Relationship, Drug; Glucose; Humans; Models, Biological; Molecular Structure; Neurons; Neuroprotective Agents; Oxygen; Pyrroles; Quinazolines; Reperfusion Injury; Stereoisomerism; Structure-Activity Relationship | 2012 |
CP-465,022, a selective noncompetitive AMPA receptor antagonist, blocks AMPA receptors but is not neuroprotective in vivo.
Topics: Animals; Brain Ischemia; Hippocampus; Male; Motor Activity; Neuroprotective Agents; Pentylenetetrazole; Quinazolines; Rats; Receptors, AMPA; Seizures; Synaptic Transmission | 2003 |
A novel and potent poly(ADP-ribose) polymerase-1 inhibitor, FR247304 (5-chloro-2-[3-(4-phenyl-3,6-dihydro-1(2H)-pyridinyl)propyl]-4(3H)-quinazolinone), attenuates neuronal damage in in vitro and in vivo models of cerebral ischemia.
Topics: Animals; Brain; Brain Ischemia; Cell Death; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Male; Mice; Neurons; PC12 Cells; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Pyridines; Quinazolines; Quinazolinones; Rats; Rats, Wistar | 2004 |
A3 adenosine receptor antagonists delay irreversible synaptic failure caused by oxygen and glucose deprivation in the rat CA1 hippocampus in vitro.
Topics: Action Potentials; Adenosine A3 Receptor Antagonists; Animals; Brain Ischemia; Hippocampus; Hypoglycemia; Hypoxia; Male; Pyridines; Quinazolines; Rats; Rats, Wistar; Receptor, Adenosine A3; Synaptic Transmission; Time Factors; Triazoles | 2006 |
Neuroprotective effects of NU1025, a PARP inhibitor in cerebral ischemia are mediated through reduction in NAD depletion and DNA fragmentation.
Topics: Animals; Apoptosis; Brain; Brain Ischemia; Cell Survival; Disease Models, Animal; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Combinations; Enzyme Inhibitors; Hydrogen Peroxide; Male; Middle Cerebral Artery; Molsidomine; NAD; Neuroprotective Agents; PC12 Cells; Poly(ADP-ribose) Polymerase Inhibitors; Quinazolines; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2006 |
CGS 15943, an adenosine A2 receptor antagonist, reduces cerebral ischemic injury in the Mongolian gerbil.
Topics: Animals; Brain Ischemia; Gerbillinae; Male; Motor Activity; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Quinazolines; Triazoles | 1994 |
Excitatory transmitter amino acid release from the ischemic rat cerebral cortex: effects of adenosine receptor agonists and antagonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aspartic Acid; Brain Ischemia; Cerebral Cortex; Glutamates; Glutamic Acid; Male; Neurotransmitter Agents; Purinergic Antagonists; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Triazoles; Xanthines | 1992 |
Involvement of lipid peroxidation and inhibitory mechanisms on ischemic neuronal damage in gerbil hippocampus: quantitative autoradiographic studies on second messenger and neurotransmitter systems.
Topics: Adenosine; Animals; Autoradiography; Body Temperature; Brain Ischemia; Calcium Channels; Chlorides; Colforsin; Gerbillinae; Hippocampus; Inositol 1,4,5-Trisphosphate; Ion Channels; Lipid Peroxidation; Male; Neurons; Neurotransmitter Agents; Pentobarbital; Phorbol 12,13-Dibutyrate; Quinazolines; Quinuclidinyl Benzilate; Receptors, GABA-A; Second Messenger Systems | 1991 |
Amelioration of brain damage after focal ischemia in the rat by a novel inhibitor of lipid peroxidation.
Topics: Animals; Brain; Brain Edema; Brain Injuries; Brain Ischemia; Cerebral Arteries; Glycerol; In Vitro Techniques; Lipid Peroxidation; Male; Mitochondria; Mitochondrial Swelling; Quinazolines; Rats; Rats, Inbred Strains | 1991 |
Prevention of hippocampus neuronal damage in ischemic gerbils by a novel lipid peroxidation inhibitor (quinazoline derivative).
Topics: Animals; Autoradiography; Brain Ischemia; Free Radicals; Gerbillinae; Hippocampus; Lipid Peroxidation; Male; Microtubule-Associated Proteins; Neurons; Pentobarbital; Phorbol 12,13-Dibutyrate; Quinazolines | 1990 |