Page last updated: 2024-08-21

quinazolines and Carcinoma, Neuroendocrine

quinazolines has been researched along with Carcinoma, Neuroendocrine in 91 studies

Research

Studies (91)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (1.10)	29.6817
2010's	76 (83.52)	24.3611
2020's	14 (15.38)	2.80

Authors

Authors	Studies
Álvarez-Escolá, C; Castelo-Fernández, B; García-Moreno, RM; Moreno-Domínguez, Ó; Torres-Sánchez, I; Yébenes-Gregorio, L	1
Brandenburg, T; Dralle, H; Führer, D; Muchalla, P; Schmid, KW; Theurer, S; Tiedje, V; Weber, F	1
Koehler, VF; Kroiss, M; Spitzweg, C	1
Hubalewska-Dydejczyk, A; Sokołowski, G; Suchmiel, M; Trofimiuk-Müldner, M; Wilczyńska, M	1
Agate, L; Bottici, V; Cappagli, V; Ciampi, R; Elisei, R; Matrone, A; Molinaro, E; Piaggi, P; Ramone, T; Romei, C; Tacito, A; Valerio, L; Viola, D	1
Su, Z; Tang, J; Wang, H	1
Forssell-Aronsson, E; Montelius, M; Nilsson, O; Sandblom, V; Shubbar, E; Spetz, J; Ståhl, I; Swanpalmer, J	1
Bastholt, L; Colzani, R; Elisei, R; Foster, M; Haddad, R; Hauch, O; Jarząb, B; Kreissl, MC; Robinson, B; Schlumberger, M; Weiss, R	1
Baudin, E; Berdelou, A; Borget, I; Hecht, F; Leboulleux, S; Ramos, HE; Schlumberger, M	1
Balcı, Y; Çağlar Çıtak, E; Demir Gündoğan, B; Sağcan, F; Tuğ Bozdoğan, S; Tuncel Daloğlu, F	1
Adam, P; Allelein, S; Berg, E; Frank-Raue, K; Hoster, E; Koehler, VF; Kroiss, M; Raue, F; Schott, M; Spitzweg, C	1
Ahn, J; Jeon, MJ; Kang, HC; Kim, BH; Kim, HK; Kim, IJ; Kim, M; Kim, TY; Lim, DJ; Shong, YK; Yoon, JH	1
Ahn, HY; Chae, JE; Kim, SG; Moon, H; Noh, J; Park, YJ	1
Borghi, MO; Cantone, MC; Carra, S; Dicitore, A; Gaudenzi, G; Ghilardi, A; Hofland, LJ; Persani, L; Plebani, A; Saronni, D; Vitale, G	1
Hong, SK; Park, JI; Starenki, D; Wu, PK	1
Cochin, V; Godbert, Y; Gross-Goupil, M; Le Moulec, S; Ravaud, A	1
Hedayati, M; Rajabi, S	1
Hadoux, J; Schlumberger, M	1
Baple, EL; Brooke, A; Derse-Anthony, C; Glod, J; Newbold, K; Osborne, N; Sturley, R; Thomas, N; Vaidya, B	1
Bumrah, C; Cote, GJ; Giordano, TJ; Knippler, CM; Miles, W; Ringel, MD; Saji, M; Valenciaga, A; Yilmaz, AS; Yu, L; Zhang, X	1
Balasubramaniam, S; Del Rivero, J; Edgerly, M; Fojo, T; Gramza, AW; Madan, RA; Ward, J	1
MacGregor, FB; Milner, TD; Reed, N; Ronghe, M; Shaikh, MG	1
Bauer, J; Grimm, D; Grosse, J; Infanger, M; Kopp, S; Krüger, M; Milling, RV; Wehland, M	1
Colombo, C; De Leo, S; Di Stefano, M; Fugazzola, L; Persani, L; Vannucchi, G	1
Dedecjus, M; Druce, M; Elisei, R; Gagel, RF; Hu, MI; Kapiteijn, E; Krajewska, J; Locati, L; Pacini, F; Popovtzer, A; Weiss, R	1
Balasubramanian, S; Carroll, C; Hamilton, J; Kaltenthaler, E; Moss, L; Tappenden, P; Wadsley, J; Wong, R	1
Cunnane, ME; Randolph, GW; Ross, DS; Sadow, PM; Wirth, LJ	1
Burttet, LM; Cerski, MR; Dora, JM; Maia, AL; Scheffel, RS; Siqueira, DR	1
Park, JI; Starenki, D	1
Antoun, S; Baracos, VE; Baudin, E; Borget, I; Broutin, S; Deroussent, A; Leboulleux, S; Massicotte, MH; Paci, A; Schlumberger, M	1
Durante, C; Filetti, S; Paciaroni, A; Plasmati, K; Trulli, F	1
Banaszynski, ME; Kolesar, JM; Ton, GN	1
Aikin, A; Balis, FM; Chuk, MK; Dombi, E; Fox, E; Lodish, M; Marcus, L; Merino, MJ; Steinberg, SM; Wells, SA; Whitcomb, PO; Widemann, BC	1
Bedard, PL; Castonguay, V; Chen, EX; Chen, H; Chen, Z; Clarke, B; Cohen, B; Hirte, HW; Hotte, SJ; Ivy, SP; Kamel-Reid, S; Liu, G; McGarrity, A; Oza, AM; Razak, AR; Reedijk, M; Sahebjam, S; Siu, LL; Wang, L; Zhang, T; Zhang, WJ	1
Baudry, C; Groussin, L; Paepegaey, AC	1
Postel-Vinay, S; Schlumberger, M; Soria, JC	1
Chen, Z; Chowdry, RP; Khuri, FR; Kim, S; Owonikoko, TK; Saba, NF; Shin, DM	1
Capdevila, J; Filetti, S; Grande, E; Kreissl, MC; Newbold, K; Reinisch, W; Robert, C; Schlumberger, M; Tolstrup, LK; Zamorano, JL	1
Bidart, JM; Broutin, S; Caillou, B; Commo, F; De Koning, L; Dubois, T; Dupuy, C; Lacroix, L; Marty-Prouvost, B; Ryan, AJ; Schlumberger, M; Talbot, M	1
Alghamdi, W; Cooper, MR; Shaheen, DJ; Steinberg, M; Yi, SY	1
Baudin, E; Borson-Chazot, F; Hescot, S; Lombès, M	1
Baudin, E; Bonichon, F; Borget, I; Brassard, M; Chougnet, CN; Claude-Desroches, M; de la Fouchardière, C; Do Cao, C; Giraudet, AL; Leboulleux, S; Massicotte, MH; Schlumberger, M	1
Anagnostis, P; Karras, S; Krassas, GE	1
Balis, FM; Derdak, J; Fox, E; Kebebew, E; Lodish, MB; Nella, AA; Quezado, MM; Stratakis, CA; Whitcomb, PO; Widemann, BC	1
Camacho, D; Kumarasamy, V; Shin, YJ; Sun, D	1
Cohen, PR; Jalalat, SZ	1
Cabanillas, ME; Hu, MI; Jimenez, C	1
Baudin, E; Chougnet, CN; Leboulleux, S; Schlumberger, M	1
Byeon, JH; Jung, YH; Kim, HR; Kim, TJ; Lim, JU; Park, CK; Woo, IS	1
Bardet, S; Bonichon, F; Borget, I; Chauffert, B; Chougnet, CN; Criniere, L; de la Fouchardiere, C; Drui, D; Leboulleux, S; Niccoli, P; Rohmer, V; Schlumberger, M; Schneegans, O; Schvartz, C; Zanetta, S	1
Alessandrini, S; Baldini, E; Catania, A; Coccaro, C; D'Armiento, M; Filippini, A; Morrone, S; Prinzi, N; Rendina, R; Sorrenti, S; Tuccilli, C; Ulisse, S	1
Bueno, F; Cross, G; Lucas, S; Pitoia, F; Schmidt, A	1
Covell, LL; Ganti, AK	1
Bradshaw, N; Davidson, R; MacGregor, FB; Narayanan, VK; Reed, N; Ronghe, M; Shaikh, MG; Welbury, R	1
Bandaru, S; Dunna, NR; Girdhar, A; Hussain, T; Kandula, V; Nayarisseri, A; Pudutha, A	1
Buck, AK; Grelle, I; Hänscheid, H; Herrmann, K; Higuchi, T; Lapa, C; Lückerath, K; Muegge, DO; Reiners, C; Schmid, JS; Werner, RA	1
Hadoux, J; Pacini, F; Schlumberger, M; Tuttle, RM	1
Barbry, P; Belléannée, G; Blanck, O; Bonnetaud, C; Bordone, O; Bozec, A; Brest, P; Butori, C; Catargi, B; Guevara, N; Hénaoui, IS; Hofman, P; Hofman, V; Ilie, M; Lassalle, S; Lemaire, G; Long, E; Mari, B; Patey, M; Peyrottes, I; Popa, A; Sadoul, JL; Santini, J; Tissier, F; Trouette, H; Vielh, P; Zangari, J	1
Ali, SM; Busaidy, NL; Chmielecki, J; Elvin, JA; Erlich, RL; Heilmann, AM; Khan, SA; Lipson, D; Miller, VA; Murthy, R; Nangia, C; Ross, JS; Shah, MH; Sherman, SI; Stephens, PJ; Subbiah, I; Subbiah, V; Sun, JX; Vergilio, JA; Wang, K; Yelensky, R	1
Learoyd, DL; Robinson, BG; Tsang, VH	1
Chabre, O; Dupuis, C; Durand, C; Piolat, C; Plantaz, D; Segura, D	1
Antonelli, A; Baldini, E; Biricotti, M; Fallahi, P; Ferrari, SM; Materazzi, G; Miccoli, P; Ulisse, S	1
Chen, AY; Ernani, V; Kumar, M; Owonikoko, TK	1
Horiuchi, K; Ito, Y; Komoda, M; Okamoto, T; Rito, K; Takahashi, S; Todo, T; Tomomatsu, J; Tsuji, A; Uchino, K	1
Alifano, M; Bienvenu-Perrard, M; Bricaire, L; Burnichon, N; Cochand-Priollet, B; Groussin, L; Lahlou, N; Louiset, E; Paepegaey, AC; Sarfati, PO	1
Georgieva, I; Grabowski, P; Holstein, J; Hopfenmüller, W; Koychev, D; Wang, Y; Zeitz, M	1
Anthoney, A; Blatter, J; Dean, E; Hanauske, AR; Kletzl, H; Klingelschmitt, G; Melezinek, I; Ranson, M; Reck, M; Twelves, C	1
Hu, MI	1
Commander, H; Perry, C; Whiteside, G	1
Baudin, E; Dralle, H; Elisei, R; Fagin, JA; Gagel, RF; Jarzab, B; Langmuir, P; Read, J; Robinson, BG; Ryan, AJ; Santoro, M; Schlumberger, MJ; Vasselli, JR; Wells, SA	1
Rischin, D; Solomon, B	1
Barberis, M; Catania, C; De Pas, TM; Giovannini, M; Labianca, R; Manzotti, M; Spaggiari, L; Toffalorio, F; Trifirò, G	1
Houvras, Y	1
Benoit, A; Cho, TH; de la Fouchardière, C; Derbel, O; Duplomb, S; Mechtouff-Cimarelli, L; Peix, JL	1
Almeida, MQ; Hoff, AO	1
Bago-Horvath, Z; Berger, W; Filipits, M; Grusch, M; Haitel, A; Hayden, H; Komina, O; Lackner, A; Pirker, C; Schmid, K; Sieghart, W; Węsierska-Gądek, J	1
Damse, A; Lacouture, ME; Rosen, AC; Sherman, E; Wu, S	1
Baudin, E; Chougnet, C; Leboulleux, S; Massicotte, MH; Nascimento, CL; Schlumberger, M	1
Balakrishnan, S; Booth, B; Chattopadhyay, S; Dorsam, R; Duan, J; Garnett, C; Gehrke, B; Ghosh, D; Ibrahim, A; Justice, R; Kim, G; Liu, Q; Maher, VE; Marathe, A; Miksinski, SP; Moon, YJ; Murgo, A; Pazdur, R; Sarker, H; Skarupa, L; Song, P; Tang, S; Thornton, K; Verbois, L; Wilson, W; Zhu, H	1
Frampton, JE	1
Frampton, JE; Keating, GM; Lyseng-Williamson, KA	1
Kimura, Y; Morikawa, N; Murakami, K; Nagano, Y; Tabata, T; Yanagisawa, S	1
Furberg, CD; Moore, TJ	1
Baum, RP; Briest, F; Grabowski, P; Hörsch, D; Kulkarni, HR; Zaknun, JJ; Zeitz, M	1
Chau, NG; Haddad, RI	1
Gonzalez, D; Nicholson, AG; Nutting, CM; O'Brien, M; Popat, S; Wotherspoon, A	1
Gerst, B; Höpfner, M; Scherübl, H; Sutter, AP; Zeitz, M	1

Reviews

25 review(s) available for quinazolines and Carcinoma, Neuroendocrine

Article	Year
Long-term follow-up and safety of vandetanib for advanced medullary thyroid cancer. Endocrine, 2021, Volume: 71, Issue:2 Topics: Acute Disease; Adult; Antineoplastic Agents; Carcinoma, Neuroendocrine; Disease-Free Survival; Follow-Up Studies; France; Humans; Pancreatitis; Piperidines; Quinazolines; Thyroid Neoplasms	2021
Medullary Thyroid Cancer: Clinical Characteristics and New Insights into Therapeutic Strategies Targeting Tyrosine Kinases. Molecular diagnosis & therapy, 2017, Volume: 21, Issue:6 Topics: Anilides; Antineoplastic Agents; Carcinoma, Neuroendocrine; Clinical Trials as Topic; High-Throughput Nucleotide Sequencing; Humans; Molecular Targeted Therapy; Mutation; Piperidines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyridines; Quinazolines; Thyroid Neoplasms	2017
Chemotherapy and tyrosine-kinase inhibitors for medullary thyroid cancer. Best practice & research. Clinical endocrinology & metabolism, 2017, Volume: 31, Issue:3 Topics: Anilides; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Neuroendocrine; Disease-Free Survival; Humans; Molecular Targeted Therapy; Neoplasm Metastasis; Piperidines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyridines; Quinazolines; Thyroid Neoplasms	2017
Pazopanib, Cabozantinib, and Vandetanib in the Treatment of Progressive Medullary Thyroid Cancer with a Special Focus on the Adverse Effects on Hypertension. International journal of molecular sciences, 2018, Oct-20, Volume: 19, Issue:10 Topics: Anilides; Carcinoma, Neuroendocrine; Cardiotoxicity; Humans; Hypertension; Indazoles; Piperidines; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Quinazolines; Sulfonamides; Thyroid Neoplasms	2018
Cabozantinib and vandetanib for unresectable locally advanced or metastatic medullary thyroid cancer: a systematic review and economic model. Health technology assessment (Winchester, England), 2019, Volume: 23, Issue:8 Topics: Anilides; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Neuroendocrine; Cost-Benefit Analysis; England; Humans; Models, Economic; Piperidines; Pyridines; Quality-Adjusted Life Years; Quinazolines; Technology Assessment, Biomedical; Thyroid Neoplasms	2019
Vandetanib: opening a new treatment practice in advanced medullary thyroid carcinoma. Endocrine, 2013, Volume: 44, Issue:2 Topics: Antineoplastic Agents; Carcinoma, Neuroendocrine; Disease Progression; Drugs, Investigational; Humans; Medical Oncology; Piperidines; Professional Practice; Quinazolines; Thyroid Neoplasms; Treatment Outcome	2013
Vandetanib: a novel targeted therapy for the treatment of metastatic or locally advanced medullary thyroid cancer. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2013, May-15, Volume: 70, Issue:10 Topics: Antineoplastic Agents; Carcinoma, Neuroendocrine; Clinical Trials as Topic; Disease-Free Survival; ErbB Receptors; Fees, Pharmaceutical; Humans; Piperidines; Quinazolines; Thyroid Neoplasms	2013
Vandetanib in advanced medullary thyroid cancer: review of adverse event management strategies. Advances in therapy, 2013, Volume: 30, Issue:11 Topics: Carcinoma, Neuroendocrine; Cardiovascular Diseases; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Eruptions; Drug-Related Side Effects and Adverse Reactions; Female; Gastrointestinal Diseases; Humans; Male; Neoplasm Invasiveness; Neoplasm Staging; Patient Selection; Piperidines; Prognosis; Quinazolines; Risk Assessment; Thyroid Neoplasms; Treatment Outcome	2013
Vandetanib for the treatment of medullary thyroid carcinoma. The Annals of pharmacotherapy, 2014, Volume: 48, Issue:3 Topics: Antineoplastic Agents; Carcinoma, Medullary; Carcinoma, Neuroendocrine; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Disease-Free Survival; Drug Interactions; Drug Labeling; Humans; Neoplasm Metastasis; Piperidines; Quinazolines; Randomized Controlled Trials as Topic; Thyroid Neoplasms	2014
[Targeted therapies, prognostic and predictive factors in endocrine oncology]. Annales d'endocrinologie, 2013, Volume: 74 Suppl 1 Topics: Antineoplastic Agents; Carcinoma, Neuroendocrine; Clinical Trials, Phase III as Topic; Disease-Free Survival; Endocrine Gland Neoplasms; Everolimus; Humans; Indoles; Molecular Targeted Therapy; Neuroendocrine Tumors; Niacinamide; Pancreatic Neoplasms; Phenylurea Compounds; Piperidines; Prognosis; Pyrroles; Quinazolines; Sirolimus; Sorafenib; Sunitinib; Thyroid Neoplasms; Treatment Outcome	2013
Vandetanib for the treatment of thyroid cancer: an update. Expert opinion on drug metabolism & toxicology, 2014, Volume: 10, Issue:3 Topics: Animals; Carcinoma, Neuroendocrine; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Disease Models, Animal; Drug Evaluation, Preclinical; Epidermal Growth Factor; Humans; Piperidines; Protein Kinase Inhibitors; Quinazolines; Randomized Controlled Trials as Topic; Thyroid Neoplasms; Transfection; Treatment Outcome; Vascular Endothelial Growth Factor Receptor-2	2014
[Vandetanib, in the management of patients with locally advanced or metastatic medullary thyroid carcinomas]. Bulletin du cancer, 2014, Volume: 101, Issue:9 Topics: Antineoplastic Agents; Carcinoma, Medullary; Carcinoma, Neuroendocrine; Humans; Piperidines; Proto-Oncogene Proteins c-ret; Quinazolines; Rare Diseases; Thyroid Neoplasms	2014
Treatment of advanced thyroid cancer: role of molecularly targeted therapies. Targeted oncology, 2015, Volume: 10, Issue:3 Topics: Anilides; Antineoplastic Agents; Axitinib; Carcinoma, Neuroendocrine; DNA Mutational Analysis; Drug Approval; Humans; Imidazoles; Indazoles; Indoles; MAP Kinase Signaling System; Molecular Targeted Therapy; Niacinamide; Oligonucleotides; Phenylurea Compounds; Phosphatidylinositol 3-Kinases; Piperidines; Proto-Oncogene Proteins c-ret; Pyridines; Pyrimidines; Pyrroles; Quinazolines; Quinolines; Sorafenib; Sulfonamides; Sunitinib; Thyroid Neoplasms; United States; United States Food and Drug Administration; Vascular Endothelial Growth Factor A	2015
Management of advanced medullary thyroid cancer. The lancet. Diabetes & endocrinology, 2016, Volume: 4, Issue:1 Topics: Anilides; Antineoplastic Agents; Biomarkers; Calcitonin; Carcinoembryonic Antigen; Carcinoma, Neuroendocrine; Disease Progression; Disease-Free Survival; Humans; Molecular Targeted Therapy; Piperidines; Pyridines; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Thyroid Neoplasms; Treatment Outcome	2016
The safety of vandetanib for the treatment of thyroid cancer. Expert opinion on drug safety, 2016, Volume: 15, Issue:8 Topics: Animals; Antineoplastic Agents; Carcinoma, Neuroendocrine; Disease-Free Survival; Humans; Piperidines; Protein Kinase Inhibitors; Quality of Life; Quinazolines; Survival Rate; Thyroid Neoplasms	2016
The safety and efficacy of vandetanib in the treatment of progressive medullary thyroid cancer. Expert review of anticancer therapy, 2016, Volume: 16, Issue:11 Topics: Adolescent; Adult; Animals; Antineoplastic Agents; Carcinoma, Neuroendocrine; Child; Disease Progression; Disease-Free Survival; Humans; Piperidines; Protein Kinase Inhibitors; Quality of Life; Quinazolines; Thyroid Neoplasms	2016
Systemic treatment and management approaches for medullary thyroid cancer. Cancer treatment reviews, 2016, Volume: 50 Topics: Anilides; Antineoplastic Agents; Carcinoma, Neuroendocrine; Chemotherapy, Adjuvant; Genotype; Humans; Molecular Targeted Therapy; Phenotype; Piperidines; Proto-Oncogene Mas; Proto-Oncogene Proteins c-ret; Pyridines; Quinazolines; Receptors, Fibroblast Growth Factor; Thyroid Neoplasms; Thyroidectomy; Vascular Endothelial Growth Factor Receptor-2	2016
Vandetanib (Caprelsa) for medullary thyroid cancer. The Medical letter on drugs and therapeutics, 2012, Jan-09, Volume: 54, Issue:1381 Topics: Carcinoma, Neuroendocrine; Drug Costs; Drug Interactions; Humans; Piperidines; Quinazolines; Randomized Controlled Trials as Topic; Thyroid Neoplasms	2012
Recent advances in the molecular pathogenesis and targeted therapies of medullary thyroid carcinoma. Current opinion in oncology, 2012, Volume: 24, Issue:3 Topics: Antineoplastic Agents; Carcinoma, Neuroendocrine; Clinical Trials, Phase III as Topic; Female; Humans; Male; Molecular Targeted Therapy; Mutation; Piperidines; Prognosis; Quinazolines; Signal Transduction; Thyroid Neoplasms; Time Factors; TOR Serine-Threonine Kinases	2012
Risk of rash in cancer patients treated with vandetanib: systematic review and meta-analysis. The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:4 Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma, Neuroendocrine; Carcinoma, Non-Small-Cell Lung; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Drug Eruptions; ErbB Receptors; Female; Humans; Incidence; Lung Neoplasms; Male; Piperidines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-ret; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Risk; Severity of Illness Index; Small Cell Lung Carcinoma; Thyroid Neoplasms	2012
Kinase inhibitors for advanced medullary thyroid carcinoma. Clinics (Sao Paulo, Brazil), 2012, Volume: 67 Suppl 1 Topics: Antineoplastic Agents; Carcinoma, Medullary; Carcinoma, Neuroendocrine; Clinical Trials as Topic; Humans; Molecular Targeted Therapy; Patient Selection; Piperidines; Protein Kinase Inhibitors; Quinazolines; Thyroid Neoplasms	2012
Vandetanib: in medullary thyroid cancer. Drugs, 2012, Jul-09, Volume: 72, Issue:10 Topics: Administration, Oral; Antineoplastic Agents; Carcinoma, Neuroendocrine; Disease-Free Survival; Humans; Molecular Structure; Neoplasm Metastasis; Piperidines; Protein-Tyrosine Kinases; Quinazolines; Randomized Controlled Trials as Topic; Thyroid Neoplasms	2012
Vandetanib: a guide to its use in advanced medullary thyroid cancer. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy, 2012, Dec-01, Volume: 26, Issue:6 Topics: Carcinoma, Neuroendocrine; Disease-Free Survival; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; Piperidines; Practice Guidelines as Topic; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Quinazolines; Thyroid Neoplasms	2012
Vandetanib therapy in medullary thyroid cancer. Drugs of today (Barcelona, Spain : 1998), 2012, Volume: 48, Issue:11 Topics: Animals; Antineoplastic Agents; Carcinoma, Neuroendocrine; Drug Interactions; ErbB Receptors; Humans; Piperidines; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins c-ret; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Thyroid Neoplasms	2012
Vandetanib for the treatment of medullary thyroid cancer. Clinical cancer research : an official journal of the American Association for Cancer Research, 2013, Feb-01, Volume: 19, Issue:3 Topics: Antineoplastic Agents; Carcinoma, Neuroendocrine; Clinical Trials as Topic; Humans; Piperidines; Protein Kinase Inhibitors; Quinazolines; Thyroid Neoplasms; Treatment Outcome	2013

Trials

10 trial(s) available for quinazolines and Carcinoma, Neuroendocrine

Article	Year
Phase I/II Trial of Vandetanib and Bortezomib in Adults with Locally Advanced or Metastatic Medullary Thyroid Cancer. The oncologist, 2019, Volume: 24, Issue:1 Topics: Antineoplastic Agents; Bortezomib; Carcinoma, Neuroendocrine; Female; Humans; Male; Piperidines; Proto-Oncogene Mas; Quinazolines; Thyroid Neoplasms	2019
Safety and efficacy of two starting doses of vandetanib in advanced medullary thyroid cancer. Endocrine-related cancer, 2019, 02-01, Volume: 26, Issue:2 Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Carcinoma, Neuroendocrine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Piperidines; Protein Kinase Inhibitors; Quinazolines; Thyroid Neoplasms; Young Adult	2019
Body composition variation and impact of low skeletal muscle mass in patients with advanced medullary thyroid carcinoma treated with vandetanib: results from a placebo-controlled study. The Journal of clinical endocrinology and metabolism, 2013, Volume: 98, Issue:6 Topics: Adult; Aged; Body Composition; Carcinoma, Neuroendocrine; Cross-Over Studies; Female; Humans; Male; Middle Aged; Muscle, Skeletal; Piperidines; Protein Kinase Inhibitors; Quinazolines; Thyroid Neoplasms	2013
Vandetanib in children and adolescents with multiple endocrine neoplasia type 2B associated medullary thyroid carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research, 2013, Aug-01, Volume: 19, Issue:15 Topics: Adolescent; Carcinoma, Medullary; Carcinoma, Neuroendocrine; Child; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; Gene Expression Regulation, Neoplastic; Germ-Line Mutation; Humans; Multiple Endocrine Neoplasia Type 2b; Neoplasm Metastasis; Neoplasm Recurrence, Local; Piperidines; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins c-ret; Quinazolines; Thyroid Neoplasms	2013
A phase I study of the combination of ro4929097 and cediranib in patients with advanced solid tumours (PJC-004/NCI 8503). British journal of cancer, 2013, Aug-20, Volume: 109, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzazepines; Breast Neoplasms; Carcinoma, Neuroendocrine; Carcinoma, Renal Cell; Colorectal Neoplasms; Female; Humans; Kidney Neoplasms; Leiomyosarcoma; Male; Middle Aged; Neoplasms; Quinazolines; Sarcoma, Endometrial Stromal; Thyroid Neoplasms; Treatment Outcome; Uterine Neoplasms; Young Adult	2013
Clinical efficacy of targeted biologic agents as second-line therapy of advanced thyroid cancer. The oncologist, 2013, Volume: 18, Issue:12 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Neuroendocrine; Disease-Free Survival; Everolimus; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Molecular Targeted Therapy; Niacinamide; Phenylurea Compounds; Piperidines; Quinazolines; Retrospective Studies; Sirolimus; Sorafenib; Thyroid Neoplasms; Treatment Outcome	2013
SAFETY AND TOLERABILITY OF VANDETANIB IN JAPANESE PATIENTS WITH MEDULLARY THYROID CANCER: A PHASE I/II OPEN-LABEL STUDY. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2017, Volume: 23, Issue:2 Topics: Adult; Aged; Antineoplastic Agents; Asian People; Carcinoma, Neuroendocrine; Disease-Free Survival; ErbB Receptors; Female; Humans; Male; Middle Aged; Piperidines; Quinazolines; Thyroid Neoplasms; Treatment Outcome	2017
Erlotinib in combination with pemetrexed for patients with advanced non-small-cell lung cancer (NSCLC): a phase I dose-finding study. Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:11 Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Large Cell; Carcinoma, Neuroendocrine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Disease Progression; ErbB Receptors; Erlotinib Hydrochloride; Female; Glutamates; Guanine; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Mutation; Neoplasm Staging; Pemetrexed; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Quinazolines; ras Proteins; Survival Rate; Time Factors; Tissue Distribution; Treatment Outcome	2010
Vandetanib in patients with locally advanced or metastatic medullary thyroid cancer: a randomized, double-blind phase III trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jan-10, Volume: 30, Issue:2 Topics: Carcinoma, Neuroendocrine; Disease Progression; Double-Blind Method; Female; Humans; Male; Middle Aged; Neoplasm Metastasis; Piperidines; Placebos; Quinazolines; Thyroid Neoplasms	2012
Vandetanib for the treatment of symptomatic or progressive medullary thyroid cancer in patients with unresectable locally advanced or metastatic disease: U.S. Food and Drug Administration drug approval summary. Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Jul-15, Volume: 18, Issue:14 Topics: Carcinoma, Neuroendocrine; Disease-Free Survival; Drug Approval; Humans; Piperidines; Quinazolines; Thyroid Neoplasms; United States; United States Food and Drug Administration	2012

Other Studies

56 other study(ies) available for quinazolines and Carcinoma, Neuroendocrine

Article	Year
An Unusual Case of Hypopituitarism as an Adverse Effect of Vandetanib and Remission of Breast Metastases in a Patient with Medullary Thyroid Cancer. Oncology research and treatment, 2021, Volume: 44, Issue:10 Topics: Carcinoma, Neuroendocrine; Female; Humans; Hypopituitarism; Piperidines; Quinazolines; Thyroid Neoplasms	2021
Continued Discontinuation of TKI Treatment in Medullary Thyroid Carcinoma - Lessons From Individual Cases With Long-Term Follow-Up. Frontiers in endocrinology, 2021, Volume: 12 Topics: Adult; Carcinoma, Neuroendocrine; Drug-Related Side Effects and Adverse Reactions; Female; Follow-Up Studies; Humans; Male; Middle Aged; Piperidines; Prognosis; Protein Kinase Inhibitors; Quinazolines; Retrospective Studies; Thyroid Neoplasms; Withholding Treatment; Young Adult	2021
[Medullary thyroid carcinoma: current clinical progress]. Deutsche medizinische Wochenschrift (1946), 2021, Volume: 146, Issue:23 Topics: Anilides; Antineoplastic Agents; Carcinoma, Neuroendocrine; Humans; Piperidines; Pyridines; Quinazolines; Thyroid Neoplasms	2021
Disseminated medullary thyroid cancer - an alternative therapeutic approach. Endokrynologia Polska, 2022, Volume: 73, Issue:5 Topics: Antineoplastic Agents; Carcinoma, Neuroendocrine; Humans; Piperidines; Quinazolines; Thyroid Neoplasms	2022
Medullary thyroid cancer treated with vandetanib: predictors of a longer and durable response. Endocrine-related cancer, 2020, 01-20, Volume: 27, Issue:2 Topics: Adolescent; Adult; Aged; Carcinoma, Neuroendocrine; Female; Humans; Male; Middle Aged; Piperidines; Quinazolines; Thyroid Neoplasms; Young Adult	2020
YAP confers resistance to vandetanib in medullary thyroid cancer. Biochemistry and cell biology = Biochimie et biologie cellulaire, 2020, Volume: 98, Issue:3 Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents; Carcinoma, Neuroendocrine; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Female; Gene Silencing; Humans; Inhibitory Concentration 50; Mice; Mice, Nude; Mutation; Piperidines; Proto-Oncogene Proteins c-ret; Quinazolines; Signal Transduction; Thyroid Neoplasms; Transcription Factors; Xenograft Model Antitumor Assays; YAP-Signaling Proteins	2020
Increased therapeutic effect on medullary thyroid cancer using a combination of radiation and tyrosine kinase inhibitors. PloS one, 2020, Volume: 15, Issue:5 Topics: Anilides; Animals; Carcinoma, Neuroendocrine; Chemoradiotherapy; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Piperidines; Protein-Tyrosine Kinases; Pyridines; Quinazolines; Thyroid Neoplasms; Xenograft Model Antitumor Assays	2020
Efficacy and Safety of Vandetanib in Progressive and Symptomatic Medullary Thyroid Cancer: Post Hoc Analysis From the ZETA Trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2020, 08-20, Volume: 38, Issue:24 Topics: Adult; Carcinoma, Neuroendocrine; Disease Progression; Female; Humans; Male; Middle Aged; Piperidines; Quinazolines; Survival Analysis; Thyroid Neoplasms	2020
Vandetanib in a Child Affected by Neurofibromatosis Type 1 and Medullary Thyroid Carcinoma with Both Journal of clinical research in pediatric endocrinology, 2021, 08-23, Volume: 13, Issue:3 Topics: Adolescent; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Neuroendocrine; Germ-Line Mutation; Homozygote; Humans; Male; Neurofibromatosis 1; Neurofibromin 1; Piperidines; Proto-Oncogene Proteins c-ret; Quinazolines; Thyroid Neoplasms; Treatment Outcome	2021
Real-World Efficacy and Safety of Cabozantinib and Vandetanib in Advanced Medullary Thyroid Cancer. Thyroid : official journal of the American Thyroid Association, 2021, Volume: 31, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anilides; Antineoplastic Agents; Carcinoma, Neuroendocrine; Female; Germany; Humans; Male; Middle Aged; Piperidines; Progression-Free Survival; Protein Kinase Inhibitors; Pyridines; Quinazolines; Registries; Retrospective Studies; Thyroid Neoplasms; Time Factors; Young Adult	2021
Vandetanib for the Management of Advanced Medullary Thyroid Cancer: A Real-World Multicenter Experience. Endocrinology and metabolism (Seoul, Korea), 2020, Volume: 35, Issue:3 Topics: Carcinoma, Neuroendocrine; Disease-Free Survival; Female; Humans; Male; Middle Aged; Piperidines; Protein Kinase Inhibitors; Quinazolines; Republic of Korea; Retrospective Studies; Thyroid Neoplasms	2020
Trends in the Diagnosis and Treatment of Patients with Medullary Thyroid Carcinoma in Korea. Endocrinology and metabolism (Seoul, Korea), 2020, Volume: 35, Issue:4 Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Carcinoma, Neuroendocrine; Child; Child, Preschool; Databases, Factual; Disease-Free Survival; Female; Forecasting; Humans; Infant; Infant, Newborn; Male; Middle Aged; National Health Programs; Piperidines; Quinazolines; Radiotherapy; Reoperation; Republic of Korea; Retrospective Studies; Sex Distribution; Thyroid Neoplasms; Thyroidectomy; Young Adult	2020
Vandetanib versus Cabozantinib in Medullary Thyroid Carcinoma: A Focus on Anti-Angiogenic Effects in Zebrafish Model. International journal of molecular sciences, 2021, Mar-16, Volume: 22, Issue:6 Topics: Angiogenesis Inhibitors; Anilides; Animals; Apoptosis; Carcinoma, Neuroendocrine; Cell Cycle; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Embryo, Nonmammalian; Humans; Neovascularization, Pathologic; Neovascularization, Physiologic; Piperidines; Pyridines; Quinazolines; Thyroid Neoplasms; Zebrafish	2021
Vandetanib and cabozantinib potentiate mitochondria-targeted agents to suppress medullary thyroid carcinoma cells. Cancer biology & therapy, 2017, Jul-03, Volume: 18, Issue:7 Topics: Anilides; Animals; Carcinoma, Neuroendocrine; Cell Cycle; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Membrane Potential, Mitochondrial; Mice; Mitochondria; Mitochondrial Dynamics; Piperidines; Protein Kinase Inhibitors; Pyridines; Quinazolines; Thyroid Neoplasms; Xenograft Model Antitumor Assays	2017
[Cabozantinib: Mechanism of action, efficacy and indications]. Bulletin du cancer, 2017, Volume: 104, Issue:5 Topics: Anilides; Antineoplastic Agents; Bone Neoplasms; Carcinoma, Neuroendocrine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Clinical Trials as Topic; Disease-Free Survival; Everolimus; Humans; Kidney Neoplasms; Lung Neoplasms; Male; Piperidines; Prostatic Neoplasms; Proto-Oncogene Proteins c-ret; Pyridines; Quinazolines; Receptor Protein-Tyrosine Kinases; Thyroid Neoplasms; Vascular Endothelial Growth Factor Receptor-2	2017
Pregnancy on vandetanib in metastatic medullary thyroid carcinoma associated with multiple endocrine neoplasia type 2B. Clinical endocrinology, 2018, Volume: 88, Issue:5 Topics: Adult; Carcinoma, Neuroendocrine; Female; Humans; Multiple Endocrine Neoplasia Type 2a; Mutation, Missense; Neoplasm Metastasis; Piperidines; Pregnancy; Quinazolines; Thyroid Neoplasms; Young Adult	2018
Transcriptional targeting of oncogene addiction in medullary thyroid cancer. JCI insight, 2018, 08-23, Volume: 3, Issue:16 Topics: Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Carcinoma, Neuroendocrine; Cell Line, Tumor; Cyclic N-Oxides; Cyclin-Dependent Kinases; Drug Resistance, Neoplasm; Drug Synergism; Enhancer Elements, Genetic; Gene Expression Regulation, Neoplastic; Humans; Indolizines; Introns; Molecular Targeted Therapy; Oncogene Addiction; Piperazines; Piperidines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-ret; Pyridines; Pyridinium Compounds; Quinazolines; Thyroid Gland; Thyroid Neoplasms; Tissue Array Analysis; Transcription, Genetic	2018
Appendix 2: Medullary Thyroid Cancer: eUpdate published online 19 February 2018 (http://www.esmo.org/Guidelines/Endocrine-and-Neuroendocrine-Cancers/Thyroid-cancer). Annals of oncology : official journal of the European Society for Medical Oncology, 2018, 10-01, Volume: 29, Issue:Suppl 4 Topics: Administration, Oral; Carcinoma, Neuroendocrine; Clinical Trials, Phase III as Topic; Europe; Humans; Medical Oncology; Piperidines; Placebos; Practice Guidelines as Topic; Progression-Free Survival; Quinazolines; Randomized Controlled Trials as Topic; Societies, Medical; Thyroid Neoplasms	2018
Vandetanib Tumor Shrinkage in Metastatic Medullary Thyroid Cancer Allowing Surgical Resection of the Primary Site: A Case Report. Journal of pediatric hematology/oncology, 2019, Volume: 41, Issue:5 Topics: Calcitonin; Carcinoembryonic Antigen; Carcinoma, Neuroendocrine; Child; Humans; Lung Neoplasms; Male; Piperidines; Quinazolines; Thyroid Neoplasms; Treatment Outcome; Tumor Burden	2019
Primary Adrenal Insufficiency During Lenvatinib or Vandetanib and Improvement of Fatigue After Cortisone Acetate Therapy. The Journal of clinical endocrinology and metabolism, 2019, 03-01, Volume: 104, Issue:3 Topics: Addison Disease; Adult; Aged; Carcinoma, Neuroendocrine; Child; Cortisone; Dose-Response Relationship, Drug; Fatigue; Female; Follow-Up Studies; Humans; Male; Middle Aged; Phenylurea Compounds; Piperidines; Protein Kinase Inhibitors; Quinazolines; Quinolines; Thyroid Neoplasms; Treatment Outcome; Young Adult	2019
Case records of the Massachusetts General Hospital. Case 5-2013. A 52-year-old woman with a mass in the thyroid. The New England journal of medicine, 2013, Feb-14, Volume: 368, Issue:7 Topics: Biopsy, Fine-Needle; Calcitonin; Carcinoma, Neuroendocrine; Diagnosis, Differential; Female; Humans; Lymph Nodes; Lymphatic Diseases; Middle Aged; Neck; Piperidines; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Thyroid Gland; Thyroid Neoplasms; Thyroid Nodule; Thyrotropin; Tomography, X-Ray Computed; Ultrasonography	2013
Toxic cardiomyopathy leading to fatal acute cardiac failure related to vandetanib: a case report with histopathological analysis. European journal of endocrinology, 2013, Volume: 168, Issue:6 Topics: Adult; Carcinoma, Neuroendocrine; Cardiomyopathies; Clinical Trials, Phase III as Topic; Fatal Outcome; Female; Heart Failure; Humans; Male; Piperidines; Protein Kinase Inhibitors; Quinazolines; Thyroid Neoplasms	2013
Mitochondria-targeted nitroxide, Mito-CP, suppresses medullary thyroid carcinoma cell survival in vitro and in vivo. The Journal of clinical endocrinology and metabolism, 2013, Volume: 98, Issue:4 Topics: Animals; Antineoplastic Agents; Carcinoma, Neuroendocrine; Cell Line, Tumor; Cell Survival; Cyclic N-Oxides; Drug Delivery Systems; Female; Humans; Mice; Mice, Nude; Mitochondria; Nitrogen Oxides; Organophosphorus Compounds; Piperidines; Proto-Oncogene Mas; Quinazolines; Thyroid Neoplasms; Xenograft Model Antitumor Assays	2013
Reversal of Cushing's syndrome by vandetanib in medullary thyroid carcinoma. The New England journal of medicine, 2013, Aug-08, Volume: 369, Issue:6 Topics: Adrenocorticotropic Hormone; Calcitonin; Carcinoma, Neuroendocrine; Cushing Syndrome; Deamino Arginine Vasopressin; Humans; Lymphatic Metastasis; Male; Middle Aged; Paraneoplastic Syndromes; Piperidines; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Thyroid Neoplasms	2013
Tumour markers fluctuations in patients with medullary thyroid carcinoma receiving long-term RET inhibitor therapy: ordinary lapping or alarming waves foreshadowing disease progression? Annals of oncology : official journal of the European Society for Medical Oncology, 2013, Volume: 24, Issue:9 Topics: Anilides; Biomarkers, Tumor; Calcitonin; Carcinoembryonic Antigen; Carcinoma, Neuroendocrine; Disease Progression; Humans; Piperidines; Proto-Oncogene Proteins c-ret; Pyridines; Quinazolines; Thyroid Neoplasms	2013
Changes in signaling pathways induced by vandetanib in a human medullary thyroid carcinoma model, as analyzed by reverse phase protein array. Thyroid : official journal of the American Thyroid Association, 2014, Volume: 24, Issue:1 Topics: Adult; Animals; Carcinoma, Neuroendocrine; Cell Line, Tumor; Cell Proliferation; Humans; MAP Kinase Signaling System; Mice; Piperidines; Proto-Oncogene Mas; Proto-Oncogene Proteins c-akt; Quinazolines; Signal Transduction; Thyroid Neoplasms	2014
Tyrosine kinase inhibitor treatments in patients with metastatic thyroid carcinomas: a retrospective study of the TUTHYREF network. European journal of endocrinology, 2014, Volume: 170, Issue:4 Topics: Adenocarcinoma; Adenocarcinoma, Follicular; Adenoma, Oxyphilic; Adult; Aged; Antineoplastic Agents; Bone Neoplasms; Carcinoma; Carcinoma, Neuroendocrine; Carcinoma, Papillary; Disease-Free Survival; Female; Humans; Indoles; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Niacinamide; Phenylurea Compounds; Piperidines; Pleural Neoplasms; Protein-Tyrosine Kinases; Pyrroles; Quinazolines; Retrospective Studies; Sorafenib; Sunitinib; Thyroid Cancer, Papillary; Thyroid Neoplasms; Treatment Outcome	2014
Vandetanib successfully controls medullary thyroid cancer-related Cushing syndrome in an adolescent patient. The Journal of clinical endocrinology and metabolism, 2014, Volume: 99, Issue:9 Topics: Adolescent; Adrenocorticotropic Hormone; Carcinoma, Neuroendocrine; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cushing Syndrome; Humans; Male; Multiple Endocrine Neoplasia Type 2b; Neoplasms, Second Primary; Piperidines; Protein-Tyrosine Kinases; Quinazolines; Thyroid Neoplasms	2014
Involvement of G-quadruplex structures in regulation of human RET gene expression by small molecules in human medullary thyroid carcinoma TT cells. Oncogene, 2015, Mar-05, Volume: 34, Issue:10 Topics: Apoptosis; Base Sequence; Carcinoma, Neuroendocrine; Cell Line; Cell Line, Tumor; G-Quadruplexes; Gene Expression Regulation, Neoplastic; Humans; Nucleotide Motifs; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Mas; Proto-Oncogene Proteins c-ret; Quinazolines; Thyroid Neoplasms; Transcriptional Activation	2015
Vandetanib-associated alopecia areata in a patient with metastatic medullary thyroid cancer. International journal of dermatology, 2015, Volume: 54, Issue:6 Topics: Adult; Alopecia Areata; Carcinoma, Neuroendocrine; Humans; Male; Piperidines; Quinazolines; Thyroid Neoplasms	2015
Medullary thyroid cancer in the era of tyrosine kinase inhibitors: to treat or not to treat--and with which drug--those are the questions. The Journal of clinical endocrinology and metabolism, 2014, Volume: 99, Issue:12 Topics: Anilides; Carcinoma, Neuroendocrine; DNA Mutational Analysis; Humans; Male; Middle Aged; Piperidines; Precision Medicine; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyridines; Quinazolines; Thyroid Neoplasms; Thyroidectomy	2014
Transformation into large-cell neuroendocrine carcinoma associated with acquired resistance to erlotinib in nonsmall cell lung cancer. The Korean journal of internal medicine, 2014, Volume: 29, Issue:6 Topics: Adenocarcinoma; Adenocarcinoma of Lung; Adult; Antineoplastic Agents; Biomarkers, Tumor; Biopsy; Carcinoma, Large Cell; Carcinoma, Neuroendocrine; Carcinoma, Non-Small-Cell Lung; Drug Resistance, Neoplasm; Erlotinib Hydrochloride; Humans; Lung Neoplasms; Magnetic Resonance Imaging; Male; Protein Kinase Inhibitors; Quinazolines; Tomography, X-Ray Computed; Treatment Outcome	2014
Vandetanib for the treatment of advanced medullary thyroid cancer outside a clinical trial: results from a French cohort. Thyroid : official journal of the American Thyroid Association, 2015, Volume: 25, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Neuroendocrine; Child; Female; France; Humans; Male; Middle Aged; Piperidines; Protein Kinase Inhibitors; Quinazolines; Retrospective Studies; Risk Factors; Thyroid Neoplasms; Time Factors; Treatment Outcome; Young Adult	2015
Preclinical testing of selective Aurora kinase inhibitors on a medullary thyroid carcinoma-derived cell line. Endocrine, 2016, Volume: 52, Issue:2 Topics: Aurora Kinase A; Aurora Kinase B; Azepines; Carcinoma, Neuroendocrine; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Organophosphates; Pyrimidines; Quinazolines; Thyroid Neoplasms	2016
Rapid response of hypercortisolism to vandetanib treatment in a patient with advanced medullary thyroid cancer and ectopic Cushing syndrome. Archives of endocrinology and metabolism, 2015, Volume: 59, Issue:4 Topics: Adult; Carcinoma, Neuroendocrine; Cushing Syndrome; Disease Progression; Female; Humans; Neoplasm Staging; Piperidines; Quinazolines; Thyroid Neoplasms; Treatment Outcome	2015
Use of Vandetanib in Metastatic Medullary Carcinoma of Thyroid in a Pediatric Patient With Multiple Endocrine Neoplasia 2B. Journal of pediatric hematology/oncology, 2016, Volume: 38, Issue:2 Topics: Antineoplastic Agents; Carcinoma, Neuroendocrine; Child; Humans; Male; Multiple Endocrine Neoplasia Type 2a; Piperidines; Quinazolines; Thyroid Neoplasms	2016
High Affinity Pharmacological Profiling of Dual Inhibitors Targeting RET and VEGFR2 in Inhibition of Kinase and Angiogeneis Events in Medullary Thyroid Carcinoma. Asian Pacific journal of cancer prevention : APJCP, 2015, Volume: 16, Issue:16 Topics: Angiogenesis Inhibitors; Anilides; Carcinoma, Neuroendocrine; Databases, Chemical; Drug Discovery; Humans; Imidazoles; Indoles; Molecular Docking Simulation; Molecular Structure; Niacinamide; Oligonucleotides; Piperidines; Protein Binding; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-ret; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Quinazolines; Sunitinib; Thyroid Neoplasms; Vascular Endothelial Growth Factor Receptor-2	2015
Prognostic Value of Serum Tumor Markers in Medullary Thyroid Cancer Patients Undergoing Vandetanib Treatment. Medicine, 2015, Volume: 94, Issue:45 Topics: Adult; Aged; Antineoplastic Agents; Biomarkers, Tumor; Calcitonin; Carcinoembryonic Antigen; Carcinoma, Neuroendocrine; Female; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Piperidines; Prognosis; Protein-Tyrosine Kinases; Quinazolines; Thyroid Neoplasms	2015
cabozantinib (COMETRIQ⁰). In medullary thyroid cancer: more harmful than beneficial, as is vandetanib. Prescrire international, 2016, Volume: 25, Issue:167 Topics: Anilides; Antineoplastic Agents; Carcinoma, Neuroendocrine; Female; Humans; Male; Piperidines; Protein Kinase Inhibitors; Pyridines; Quality of Life; Quinazolines; Thyroid Neoplasms	2016
MicroRNA-375/SEC23A as biomarkers of the in vitro efficacy of vandetanib. Oncotarget, 2016, May-24, Volume: 7, Issue:21 Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Neuroendocrine; Cell Line; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; MicroRNAs; Middle Aged; Piperidines; Quinazolines; RNA Interference; Thyroid Neoplasms; Vesicular Transport Proteins	2016
Comprehensive Genomic Profiling of Clinically Advanced Medullary Thyroid Carcinoma. Oncology, 2016, Volume: 90, Issue:6 Topics: Aged; Anilides; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Neuroendocrine; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p16; Drug Resistance, Neoplasm; Everolimus; Female; Fibroblast Growth Factor 3; Fibroblast Growth Factors; Gene Amplification; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Methionine; Middle Aged; Molecular Targeted Therapy; Mutation; Piperidines; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Pyridines; Quinazolines; Threonine; Thyroid Neoplasms	2016
[Metastatic medullary thyroid carcinoma in a child with multiple endocrine neoplasia 2B. Efficiency of medium-term treatment with vandetanib without thyroid surgery]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2016, Volume: 23, Issue:8 Topics: Carcinoma, Neuroendocrine; Child; Female; Humans; Lung Neoplasms; Multiple Endocrine Neoplasia Type 2b; Piperidines; Protein Kinase Inhibitors; Quinazolines; Thyroid Neoplasms	2016
Long-Term Control of Hypercortisolism by Vandetanib in a Case of Medullary Thyroid Carcinoma with a Somatic RET Mutation. Thyroid : official journal of the American Thyroid Association, 2017, Volume: 27, Issue:4 Topics: Calcitonin; Carcinoma, Neuroendocrine; Cushing Syndrome; Cytoreduction Surgical Procedures; Humans; Hydrocortisone; Male; Middle Aged; Neck Dissection; Piperidines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-ret; Quinazolines; Thyroid Neoplasms; Thyroidectomy	2017
ZM447439, a novel promising aurora kinase inhibitor, provokes antiproliferative and proapoptotic effects alone and in combination with bio- and chemotherapeutic agents in gastroenteropancreatic neuroendocrine tumor cell lines. Neuroendocrinology, 2010, Volume: 91, Issue:2 Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Apoptosis; Aurora Kinases; Benzamides; Carcinoid Tumor; Carcinoma, Neuroendocrine; Cell Division; Cell Line, Tumor; Cisplatin; Doxorubicin; Drug Interactions; Drug Therapy, Combination; Fluorouracil; Humans; Inhibitor of Apoptosis Proteins; Microtubule-Associated Proteins; Octreotide; Pancreatic Neoplasms; Protein Serine-Threonine Kinases; Quinazolines; Somatostatin; Streptozocin; Survivin; Synaptophysin	2010
Updates in the management of medullary thyroid cancer. Clinical advances in hematology & oncology : H&O, 2011, Volume: 9, Issue:5 Topics: Carcinoma, Neuroendocrine; Contraindications; Humans; Multiple Endocrine Neoplasia; Mutation; Piperidines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-ret; Quinazolines; Research; Syndrome; Thyroid Neoplasms	2011
Vandetanib: first global approval. Drugs, 2011, Jul-09, Volume: 71, Issue:10 Topics: Animals; Antineoplastic Agents; Carcinoma, Neuroendocrine; Drug Approval; Drug Design; Humans; Neoplasm Metastasis; Piperidines; Quinazolines; Thyroid Neoplasms; Vascular Endothelial Growth Factor Receptor-2	2011
Progress in molecular targeted therapy for thyroid cancer: vandetanib in medullary thyroid cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jan-10, Volume: 30, Issue:2 Topics: Carcinoma, Neuroendocrine; Female; Humans; Male; Piperidines; Quinazolines; Thyroid Neoplasms	2012
Large-cell neuroendocrine carcinoma of the lung harboring EGFR mutation and responding to gefitinib. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-01, Volume: 29, Issue:34 Topics: Aged; Antineoplastic Agents; Base Sequence; Carcinoma, Large Cell; Carcinoma, Neuroendocrine; Female; Gefitinib; Genes, erbB-1; Humans; Lung Neoplasms; Molecular Sequence Data; Mutation; Neoplasm Metastasis; Protein Kinase Inhibitors; Quinazolines	2011
Completing the Arc: targeted inhibition of RET in medullary thyroid cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jan-10, Volume: 30, Issue:2 Topics: Carcinoma, Neuroendocrine; Female; Humans; Male; Piperidines; Quinazolines; Thyroid Neoplasms	2012
Unusual adverse event with vandetanib in metastatic medullary thyroid cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jan-10, Volume: 30, Issue:2 Topics: Carcinoma, Neuroendocrine; Humans; Male; Middle Aged; Neoplasm Metastasis; Piperidines; Quinazolines; Thyroid Neoplasms	2012
Synergistic effects of erlotinib and everolimus on bronchial carcinoids and large-cell neuroendocrine carcinomas with activated EGFR/AKT/mTOR pathway. Neuroendocrinology, 2012, Volume: 96, Issue:3 Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Carcinoma, Bronchogenic; Carcinoma, Neuroendocrine; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Child; ErbB Receptors; Erlotinib Hydrochloride; Everolimus; Female; Humans; Lung Neoplasms; Male; Middle Aged; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinazolines; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Young Adult	2012
Large-cell neuroendocrine carcinoma with epidermal growth factor receptor mutation: possible transformation of lung adenocarcinoma. Respirology (Carlton, Vic.), 2012, Volume: 17, Issue:8 Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Carcinoma, Large Cell; Carcinoma, Neuroendocrine; Cisplatin; Combined Modality Therapy; Deoxycytidine; ErbB Receptors; Erlotinib Hydrochloride; Exons; Gemcitabine; Humans; Lung Neoplasms; Male; Middle Aged; Mutation; Neoplasm Staging; Quinazolines; Treatment Failure; Vinblastine; Vinorelbine	2012
The safety risks of innovation: the FDA's Expedited Drug Development Pathway. JAMA, 2012, Sep-05, Volume: 308, Issue:9 Topics: Anticoagulants; Antineoplastic Agents; Benzimidazoles; beta-Alanine; Carcinoma, Neuroendocrine; Clinical Trials as Topic; Dabigatran; Drug Approval; Efficiency, Organizational; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Multiple Sclerosis; Patient Safety; Piperidines; Propylene Glycols; Quinazolines; Risk; Sphingosine; Stroke; Thyroid Neoplasms; Time Factors; United States; United States Food and Drug Administration	2012
Vandetanib: too dangerous in medullary thyroid cancer. Prescrire international, 2012, Volume: 21, Issue:131 Topics: Antineoplastic Agents; Carcinoma, Neuroendocrine; Evidence-Based Medicine; Humans; Patient Safety; Piperidines; Protein Kinase Inhibitors; Quinazolines; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Thyroid Neoplasms; Treatment Outcome	2012
Transformation to "high grade" neuroendocrine carcinoma as an acquired drug resistance mechanism in EGFR-mutant lung adenocarcinoma. Lung cancer (Amsterdam, Netherlands), 2013, Volume: 80, Issue:1 Topics: Adenocarcinoma; Carcinoma, Neuroendocrine; Cell Transformation, Neoplastic; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Female; Humans; Immunohistochemistry; Lung Neoplasms; Middle Aged; Mutation; Neoplasm Grading; Protein Kinase Inhibitors; Quinazolines; Small Cell Lung Carcinoma	2013
A novel approach in the treatment of neuroendocrine gastrointestinal tumours. Targeting the epidermal growth factor receptor by gefitinib (ZD1839). British journal of cancer, 2003, Nov-03, Volume: 89, Issue:9 Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoid Tumor; Carcinoma, Neuroendocrine; Cell Cycle; Cell Line, Tumor; Dose-Response Relationship, Drug; ErbB Receptors; Fluorescent Antibody Technique; Gastrointestinal Neoplasms; Gefitinib; Gene Expression Regulation, Neoplastic; Humans; Insulinoma; Oligonucleotide Array Sequence Analysis; Pancreatic Neoplasms; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction	2003