Page last updated: 2024-08-21

quinazolines and Carcinogenesis

quinazolines has been researched along with Carcinogenesis in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.45)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's24 (82.76)24.3611
2020's4 (13.79)2.80

Authors

AuthorsStudies
Chen, MC; Li, YH; Liao, WL; Lin, H; Yang, TY1
Gu, ZL; Huang, J; Zhen, LL1
Guo, C; Li, W; Pangeni, RP; Raz, DJ; Sun, T; Wang, J; Yang, L; Yun, X; Zhang, K1
Agostini, S; Barbarino, M; Barone, E; Bottaro, M; Catalano, C; Cipollini, M; Corrado, A; Dell'Anno, I; Gemignani, F; Giordano, A; Landi, S; Luzzi, L; Melaiu, O; Melani, A; Migliore, L; Silvestri, R1
Chin, CC; Huang, YC; Kuo, YH; Lee, YR; Li, JM; Shi, CS1
Hu, Q; Xie, B; Xu, Z; Zhang, W; Zhang, X; Zheng, J; Zhou, J1
Han, R; He, Y; Jiao, L; Li, L; Wang, Y; Zheng, J1
Liu, H; Song, Q; Yang, Y; Yu, X; Yu, Y1
Cunha, SI; Jia, M; Souchelnytskyi, S1
Liu, X; Shi, F; Su, L; Sun, W; Sun, X; Wang, Y; Yao, S; Zhang, Y1
Heymach, J; Nakano, T; Nowak, AK; Popat, S; Scagliotti, GV; Tsao, A1
Brewer, M; Janakiram, NB; Mohammed, A; Rao, CV; Steele, VE; Vedala, K1
Chang, C; Chen, CC; Chuang, WM; Hsieh, TF; Hung, XF; Lin, MH; Ma, WL; Shyr, CR; Tsai, YR; Zhang, C; Zhang, Q1
Andreoli, R; Ardizzoni, A; Azzoni, C; Bartolotti, M; Bortesi, B; De Palma, G; Gelsomino, F; Goldoni, M; Mozzoni, P; Mutti, A; Silini, EM; Tiseo, M1
Antoine, M; Cadranel, J; Duruisseaux, M; Lacave, R; Lavole, A; Leprieur, EG; Rabbe, N; Rozensztajn, N; Ruppert, AM; Vieira, T; Wislez, M1
Hashimoto, M; Iwakami, S; Kato, M; Kobayashi, I; Koizumi, F; Minakata, K; Moriyama, H; Moriyama, M; Murakami, A; Nara, T; Nurwidya, F; Shimada, N; Tajima, K; Takahashi, F; Takahashi, K1
Imai, T; Ishigame, T; Kohno, T; Kumamoto, K; Saito, M; Tsuta, K1
Aldape, K; Berens, ME; Carrera-Silva, EA; Dietrich, JD; Errasti, AE; Ghosh, S; Gibbs, D; Hulme, C; Kusne, Y; Loftus, JC; Lu, Z; Mandell, EK; Perry, AS; Rothlin, CV; Rushing, EJ; Sanai, N; Yang, W1
Carretero, J; Costa, DB; Hayashi, Y; Kobayashi, SS; Li, D; Nakayama, S; Sng, N; Soejima, K; Soo, RA; Tan, AJ; Welner, R; Wong, KK; Yamaguchi, N; Yamamoto, M; Yasuda, H1
Asztalos, S; Bellis, AD; Bluver, D; Broadbelt, LJ; Dubbury, SJ; Jeruss, JS; Mui, MD; Peñalver Bernabé, B; Saez-Rodriguez, J; Shea, LD; Shin, S; Tonetti, DA; Weiss, MS1
Chen, M; Gao, B; Qin, X; Wang, J; Wang, Y; Zhang, Z1
Abt, MA; Hill, EG; Yeh, ES1
Datta, J; Lang, JC; Mapp, AK; Pan, Q; Piao, L; Teknos, TN; Xie, X; Zhang, M1
De Andrade, JP; Gu, VW; Kulak, MV; Lorenzen, AW; Park, JM; Spanheimer, PM; Van Dorin, SE; Weigel, RJ; Woodfield, GW; Wu, VT1
An, SJ; Bai, XY; Chen, ZH; Gou, LY; Su, J; Wu, YL; Xie, Z; Yang, SQ; Zhang, XC1
Ichihara, E; Kiura, K; Kubo, T; Ohashi, K; Osawa, M; Takata, M; Takata, S; Takigawa, N; Tanimoto, M1
Goto, N; Inoue, T; Kashimoto, S; Kukimoto-Niino, M; Masuda, M; Mimata, A; Moriyama, H; Ohata, H; Ohbayashi, N; Okamoto, K; Sawa, M; Shirouzu, M; Uno, Y; Yamada, T1
Lang, B; Meng, LR; Shang, C1
BALDWIN, RW; PALMER, HC; PARTRIDGE, MW1

Reviews

1 review(s) available for quinazolines and Carcinogenesis

ArticleYear
Targeting angiogenesis for patients with unresectable malignant pleural mesothelioma.
    Seminars in oncology, 2019, Volume: 46, Issue:2

    Topics: Asbestos; Bevacizumab; Carcinogenesis; Humans; Indoles; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; Neovascularization, Pathologic; Pleural Neoplasms; Quinazolines

2019

Other Studies

28 other study(ies) available for quinazolines and Carcinogenesis

ArticleYear
RAGE potentiates EGFR signaling and interferes with the anticancer effect of gefitinib on NSCLC cells.
    American journal of physiology. Cell physiology, 2023, 11-01, Volume: 325, Issue:5

    Topics: Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Resistance, Neoplasm; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Gefitinib; Humans; Ligands; Lung Neoplasms; Proto-Oncogene Proteins c-bcl-2; Quinazolines; Receptor for Advanced Glycation End Products

2023
Knockdown of otubain 2 inhibits liver cancer cell growth by suppressing NF-κB signaling.
    The Kaohsiung journal of medical sciences, 2020, Volume: 36, Issue:6

    Topics: Carcinogenesis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; Genes, Reporter; Hepatoblastoma; Humans; Liver Neoplasms; Luciferases; Phenyl Ethers; Phenylenediamines; Phosphorylation; Quinazolines; RNA, Small Interfering; Signal Transduction; Survival Analysis; Thiolester Hydrolases; Transcription Factor RelA

2020
G9a regulates tumorigenicity and stemness through genome-wide DNA methylation reprogramming in non-small cell lung cancer.
    Clinical epigenetics, 2020, 06-17, Volume: 12, Issue:1

    Topics: Animals; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Forkhead Transcription Factors; Heterografts; Histone-Lysine N-Methyltransferase; Histones; Humans; Lung Neoplasms; Mice; Neoplastic Stem Cells; Quinazolines; Repressor Proteins; RNA, Small Interfering; Sequence Analysis, RNA; Up-Regulation

2020
    International journal of molecular sciences, 2020, Jul-09, Volume: 21, Issue:14

    Topics: beta Karyopherins; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Epithelium; Eukaryotic Initiation Factor-4G; Gene Expression Regulation, Neoplastic; Humans; Mesothelioma, Malignant; Pleural Neoplasms; Quinazolines; ran GTP-Binding Protein; RNA, Small Interfering; Small Molecule Libraries

2020
Evodiamine Induces Cell Growth Arrest, Apoptosis and Suppresses Tumorigenesis in Human Urothelial Cell Carcinoma Cells.
    Anticancer research, 2017, Volume: 37, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinogenesis; Carcinoma; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Fluorescein-5-isothiocyanate; Fluorouracil; Humans; Mutation; Plant Extracts; Quinazolines; Signal Transduction; Urinary Bladder Neoplasms; Urothelium

2017
Sensitivity to chemotherapeutics of NSCLC cells with acquired resistance to EGFR-TKIs is mediated by T790M mutation or epithelial-mesenchymal transition.
    Oncology reports, 2018, Volume: 39, Issue:4

    Topics: Biomarkers, Tumor; Bridged-Ring Compounds; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Docetaxel; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; ErbB Receptors; Gefitinib; Gene Knockdown Techniques; Humans; Mutation; Neoplastic Stem Cells; Paclitaxel; Protein Kinase Inhibitors; Quinazolines; Taxoids

2018
Clinical analysis by next-generation sequencing for NSCLC patients with MET amplification resistant to osimertinib.
    Lung cancer (Amsterdam, Netherlands), 2018, Volume: 118

    Topics: Acrylamides; Adenocarcinoma of Lung; Adult; Aged; Aniline Compounds; Antineoplastic Combined Chemotherapy Protocols; Carcinogenesis; Cohort Studies; Crizotinib; Crown Ethers; Drug Resistance, Neoplasm; ErbB Receptors; Female; Gene Amplification; High-Throughput Nucleotide Sequencing; Humans; Lung Neoplasms; Male; Middle Aged; Mutation; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Quinazolines; Survival Analysis

2018
miR‑494 inhibits cancer‑initiating cell phenotypes and reverses resistance to lapatinib by downregulating FGFR2 in HER2‑positive gastric cancer.
    International journal of molecular medicine, 2018, Volume: 42, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Carcinogenesis; Cell Line, Tumor; Down-Regulation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Lapatinib; Male; MicroRNAs; Middle Aged; Quinazolines; Receptor, ErbB-2; Receptor, Fibroblast Growth Factor, Type 2; Stomach Neoplasms

2018
Exposure to EGF and 17β‑estradiol irreversibly affects the proliferation and transformation of MCF7 cells but is not sufficient to promote tumor growth in a xenograft mouse model upon withdrawal of exposure.
    International journal of molecular medicine, 2018, Volume: 42, Issue:3

    Topics: Animals; Benzamides; Carcinogenesis; Cell Proliferation; Cell Transformation, Neoplastic; Dioxoles; Epidermal Growth Factor; Estradiol; Female; Gefitinib; Humans; MCF-7 Cells; Mice, SCID; Models, Biological; Neoplastic Stem Cells; Phenotype; Quinazolines; Spheroids, Cellular; Tamoxifen; Xenograft Model Antitumor Assays

2018
Angio-associated migratory cell protein interacts with epidermal growth factor receptor and enhances proliferation and drug resistance in human non-small cell lung cancer cells.
    Cellular signalling, 2019, Volume: 61

    Topics: A549 Cells; Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Crown Ethers; Dimerization; Drug Resistance, Neoplasm; ErbB Receptors; Female; Gene Knockdown Techniques; HEK293 Cells; Heterografts; Humans; Lung Neoplasms; Mice; Phosphorylation; Quinazolines; Transfection; Tumor Burden

2019
Multitargeted low-dose GLAD combination chemoprevention: a novel and promising approach to combat colon carcinogenesis.
    Neoplasia (New York, N.Y.), 2013, Volume: 15, Issue:5

    Topics: Adenomatous Polyps; Animals; Antineoplastic Combined Chemotherapy Protocols; Atorvastatin; Carcinogenesis; Cell Proliferation; Chemoprevention; Colon; Colonic Neoplasms; Cytokines; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Eflornithine; Female; Gefitinib; Heptanoic Acids; Intestine, Small; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Molecular Targeted Therapy; Pyrroles; Quinazolines

2013
Epidermal growth factor enhances androgen receptor‑mediated bladder cancer progression and invasion via potentiation of AR transactivation.
    Oncology reports, 2013, Volume: 30, Issue:6

    Topics: Androgens; Animals; Butylhydroxybutylnitrosamine; Carcinogenesis; Castration; Disease Models, Animal; Disease Progression; Epidermal Growth Factor; ErbB Receptors; Humans; Male; Mice; Mitogen-Activated Protein Kinase Kinases; Phosphatidylinositol 3-Kinases; Quinazolines; Receptors, Androgen; Signal Transduction; Transcriptional Activation; Urinary Bladder Neoplasms

2013
Correlation between erlotinib pharmacokinetics, cutaneous toxicity and clinical outcomes in patients with advanced non-small cell lung cancer (NSCLC).
    Lung cancer (Amsterdam, Netherlands), 2014, Volume: 83, Issue:2

    Topics: Aged; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Erlotinib Hydrochloride; Female; Humans; Hydrocortisone; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Quinazolines; Skin; Survival Analysis; Treatment Outcome

2014
Factors associated with early progression of non-small-cell lung cancer treated by epidermal growth factor receptor tyrosine-kinase inhibitors.
    Cancer medicine, 2014, Volume: 3, Issue:1

    Topics: Aged; Aged, 80 and over; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Disease Progression; ErbB Receptors; Erlotinib Hydrochloride; Female; Gefitinib; Humans; Male; Middle Aged; Mutation; Prognosis; Protein Kinase Inhibitors; Quinazolines

2014
Hypoxia increases gefitinib-resistant lung cancer stem cells through the activation of insulin-like growth factor 1 receptor.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: AC133 Antigen; Animals; Antigens, CD; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Cell Line, Tumor; Cell Separation; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glycoproteins; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Insulin-Like Growth Factor I; Lung Neoplasms; Mice, Inbred NOD; Mutation; Neoplasm Transplantation; Neoplastic Stem Cells; Octamer Transcription Factor-3; Peptides; Quinazolines; Receptor, IGF Type 1; Spheroids, Cellular; Up-Regulation

2014
A mouse model of KIF5B-RET fusion-dependent lung tumorigenesis.
    Carcinogenesis, 2014, Volume: 35, Issue:11

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Carcinogenesis; Humans; Lung Neoplasms; Mice; Mice, Transgenic; Oncogene Proteins, Fusion; Piperidines; Protein Kinase Inhibitors; Quinazolines

2014
Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma.
    Science signaling, 2014, Aug-12, Volume: 7, Issue:338

    Topics: Animals; Carcinogenesis; Drug Delivery Systems; Enzyme-Linked Immunosorbent Assay; Epidermal Growth Factor; ErbB Receptors; Erlotinib Hydrochloride; Flow Cytometry; Fluorescent Antibody Technique; Glioblastoma; Humans; Immunoblotting; Immunohistochemistry; Immunoprecipitation; Kaplan-Meier Estimate; Mice; NF-kappa B; Paracrine Communication; Protein Kinase C; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tumor Necrosis Factor-alpha

2014
β-catenin contributes to lung tumor development induced by EGFR mutations.
    Cancer research, 2014, Oct-15, Volume: 74, Issue:20

    Topics: Afatinib; Animals; Antineoplastic Agents; beta Catenin; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Doxycycline; ErbB Receptors; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Lung Neoplasms; Mice, Transgenic; Mutation, Missense; Protein Stability; Quinazolines; Tumor Burden; Up-Regulation; Xenograft Model Antitumor Assays

2014
Dynamic transcription factor activity and networks during ErbB2 breast oncogenesis and targeted therapy.
    Integrative biology : quantitative biosciences from nano to macro, 2014, Volume: 6, Issue:12

    Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Survival; Computer Simulation; Female; Humans; Lapatinib; Models, Biological; Molecular Targeted Therapy; Protein Array Analysis; Quinazolines; Transcription Factors; Transcriptional Activation

2014
Crotoxin suppresses the tumorigenic properties and enhances the antitumor activity of Iressa® (gefinitib) in human lung adenocarcinoma SPCA‑1 cells.
    Molecular medicine reports, 2014, Volume: 10, Issue:6

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; Carcinogenesis; Cell Line, Tumor; Crotoxin; ErbB Receptors; G1 Phase Cell Cycle Checkpoints; Gefitinib; Humans; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; Neovascularization, Pathologic; Quinazolines

2014
Regulation of cell survival by HUNK mediates breast cancer resistance to HER2 inhibitors.
    Breast cancer research and treatment, 2015, Volume: 149, Issue:1

    Topics: Animals; Antibodies, Monoclonal, Humanized; Apoptosis; Autophagy; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Lapatinib; Mammary Neoplasms, Animal; Molecular Targeted Therapy; Protein Serine-Threonine Kinases; Quinazolines; Receptor, ErbB-2; Trastuzumab

2015
miR-124 Regulates the Epithelial-Restricted with Serine Box/Epidermal Growth Factor Receptor Signaling Axis in Head and Neck Squamous Cell Carcinoma.
    Molecular cancer therapeutics, 2015, Volume: 14, Issue:10

    Topics: Afatinib; Animals; Antineoplastic Agents; Base Sequence; Carcinogenesis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA-Binding Proteins; ErbB Receptors; Gene Expression; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Lapatinib; Mice, Nude; MicroRNAs; Neoplasm Transplantation; Proto-Oncogene Proteins c-ets; Quinazolines; RNA Interference; Signal Transduction; Transcription Factors; Tumor Burden

2015
EGFR Is Regulated by TFAP2C in Luminal Breast Cancer and Is a Target for Vandetanib.
    Molecular cancer therapeutics, 2016, Volume: 15, Issue:3

    Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Piperidines; Proto-Oncogene Proteins c-ret; Quinazolines; Transcription Factor AP-2; Tumor Burden; Xenograft Model Antitumor Assays

2016
Blockade of Hedgehog Signaling Synergistically Increases Sensitivity to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non-Small-Cell Lung Cancer Cell Lines.
    PloS one, 2016, Volume: 11, Issue:3

    Topics: Antigens, CD; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biomarkers, Tumor; Cadherins; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Line; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Gene Expression Regulation, Neoplastic; Hedgehog Proteins; Humans; Immunohistochemistry; Inhibitory Concentration 50; Lung Neoplasms; Neoplasm Proteins; Neoplastic Stem Cells; Protein Kinase Inhibitors; Quinazolines; Signal Transduction; Snail Family Transcription Factors; Transcription Factors; Up-Regulation

2016
Effect of Vandetanib on Lung Tumorigenesis in Transgenic Mice Carrying an Activating Egfr Gene Mutation.
    Acta medica Okayama, 2016, Volume: 70, Issue:4

    Topics: Animals; Antineoplastic Agents; Carcinogenesis; Carcinoma; ErbB Receptors; Gene Expression Regulation; Hyperplasia; Lung Neoplasms; Mice; Mice, Transgenic; Mutation; Piperidines; Quinazolines; Signal Transduction; Vascular Endothelial Growth Factor A

2016
TNIK inhibition abrogates colorectal cancer stemness.
    Nature communications, 2016, 08-26, Volume: 7

    Topics: Adenomatous Polyposis Coli Protein; Administration, Oral; Aged; Animals; Azoxymethane; beta Catenin; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Colorectal Neoplasms; Crystallography, X-Ray; Female; Germinal Center Kinases; Humans; Imidazoles; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Middle Aged; Mutation; Neoplastic Stem Cells; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Quinazolines; Recombinant Proteins; Ubiquitin-Protein Ligases; Wnt Proteins; Wnt Signaling Pathway; Xenograft Model Antitumor Assays

2016
Blocking NOTCH pathway can enhance the effect of EGFR inhibitor through targeting CD133+ endometrial cancer cells.
    Cancer biology & therapy, 2018, 02-01, Volume: 19, Issue:2

    Topics: AC133 Antigen; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogenesis; Cell Line, Tumor; Diamines; Drug Resistance, Neoplasm; Drug Synergism; Endometrial Neoplasms; ErbB Receptors; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Quinazolines; Receptors, Notch; Signal Transduction; Thiazoles; Tyrphostins; Xenograft Model Antitumor Assays

2018
Studies on tricycloquinazoline carcinogenesis: interaction of carcinogen with skin components.
    British journal of cancer, 1962, Volume: 16

    Topics: Carcinogenesis; Carcinogens; Humans; Quinazolines; Skin; Skin Neoplasms

1962