Page last updated: 2024-08-21

quinazolines and Cancer of Liver

quinazolines has been researched along with Cancer of Liver in 249 studies

Research

Studies (249)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (3.21)	18.7374
1990's	8 (3.21)	18.2507
2000's	76 (30.52)	29.6817
2010's	138 (55.42)	24.3611
2020's	19 (7.63)	2.80

Authors

Authors	Studies
Al-Gayyar, MMH; Alattar, A; Alshaman, R; Hamdan, AM	1
Bae, SJ; Kim, YW; Song, YR; Yun, UJ	1
Che, J; Dong, X; Du, J; Gao, J; He, Q; Lu, Y; Luo, M; Luo, P; Nie, W; Pan, C; Wang, J; Zhu, H	1
Atkinson, D; Bandula, S; Bascal, ZA; Beaton, L; Boucher, E; Chouhan, M; Clarkson, MJ; Cooper, S; Counsell, N; Czuczman, P; Davidson, BR; Forsyth, S; Hague, J; Hartley, JA; Jansen, M; Lewis, AL; Lowe, HL; Meyer, T; Munneke, G; Pollok, JM; Raja, J; Ryan, S; Sharma, D; Sharma, RA; Stuckey, DJ; Thin, MZ; Tregidgo, HFJ; Wilde, PE; Znati, SA	1
Bi, Y; Han, X; Jiao, D; Ren, J; Wang, Y	1
Bi, Y; Han, X; Jiao, D; Ren, J	1
Cui, Y; Dai, M; Hu, Y; Kong, W; Wang, X; Wu, H; Wu, J; Yu, B; Yu, X; Zhang, H; Zheng, Y	1
Bifulco, N; Boral, A; Brooijmans, N; Dorsch, M; Guzi, T; Hatlen, MA; Hoeflich, KP; Kang, YK; Kim, JL; Kim, RD; Lengauer, C; Miduturu, C; Rozsahegyi, E; Rubin, N; Schmidt-Kittler, O; Sheets, MP; Sherwin, CA; Shi, H; Wolf, BB	1
Chan, SL; Choo, SP; Dufour, JF; Faivre, S; Feun, LG; Hagel, M; Hoeflich, KP; Hollebecque, A; Kang, YK; Kim, RD; Kohl, NE; Lengauer, C; Lim, HY; Lin, ZZ; Llovet, JM; Macarulla, T; Manoogian, M; Mazzaferro, V; Meyer, T; Palmer, DH; Park, JW; Sarker, D; Schmidt-Kittler, O; Sharma, S; Sherwin, CA; Shi, H; Stransky, N; Sung, MW; Trojan, J; Tugnait, M; Wolf, BB; Yau, T; Yen, CJ; Yoon, JH; Zhu, AX	1
Kim, KW; Van den Abbeele, AD	1
Chow, EK; Gu, M; Hooi, L; Lim, JJ; Toh, TB; Zhang, X	1
Cao, J; Chen, Z; Dai, X; Gai, R; He, Q; Luo, H; Qian, M; Yan, F; Yang, B; Ye, S; Ying, M; Yuan, T; Zhu, H	1
Bu, Y; Chang, F; Jia, F; Jia, Q; Liao, X; Ren, X; Song, G; Xiao, X; Xu, Z; Zhang, M	1
Gu, ZL; Huang, J; Zhen, LL	1
Chen, DL; Guo, XX; Hu, L; Jiang, R; Li, DY; Li, J; Li, LS; Ran, JH; Tang, JF; Xu, K; Zeng, D; Zhao, S; Zhou, P	1
Gao, H; Hao, H; Li, S; Qi, C; Zhang, L; Zong, H	1
Bosserhoff, A; Dietrich, P; Freese, K; Hellerbrand, C; Seitz, T; Thasler, WE	1
Cheng, S; Du, C; Fan, X; Fu, J; Gao, Y; Li, N; Ma, J; Markowitz, GJ; Qin, W; Wang, H; Yang, B; Yang, P	1
Chen, S; Liu, W; Yu, W; Zhang, K	1
Hwang, S; Kim, I; Kim, K; Kim, S; Park, S; Yeom, J	1
Chen, J; Jin, F; Song, X; Wang, R; Wang, Y; Wu, Y; Zhu, Y	1
Carter, R; Hagan, AE; Lewis, AL; Lloyd, AW; Macfarlane, WM; Phillips, GJ; Sharma, RA; Westhorpe, A; Znati, SA	1
Austin, E; Kalomeris, T; Larimer, B; Mahmood, U; Nesti, S; Sinevici, N; Wehrenberg-Klee, E	1
Deng, J; Fan, X; Hao, X; Lei, F; Li, J; Liang, Y; Liang, Z; Liu, D; Shi, T; Wang, Z; Wen, H; Zhang, H	1
Aoyama, K; Chiba, T; Inoue, M; Iwama, A; Koide, S; Kusakabe, Y; Mimura, N; Miyagi, S; Miyazaki, M; Noguchi, Y; Ogasawara, S; Ooka, Y; Oshima, M; Otsuka, M; Saito, T; Saraya, A; Suzuki, E; Tara, S; Tawada, A; Wakamatsu, T; Yokosuka, O; Yokoyama, M; Yuki, K; Zen, Y	1
Chen, JS; Chen, KY; Chih-Hsin Yang, J; Ho, CC; Liao, WY; Lin, CC; Lin, ZZ; Shih, JY; Yao, ZH; Yu, CJ	1
Ghosh, B; Keshari, AK; Kumar, D; Kumar, U; Rai, A; Raj, V; Rawat, A; Saha, S; Singh, AK; Trivedi, P	1
Chang, CJ; Hu, CY; Lin, CH; Su, YC; Wu, CL; Wu, HT	1
Ding, Q; Li, CY; Wang, Y; Xu, T; Zhang, L; Zhou, DD	1
Gao, L; Lv, F; Shay, C; Teng, Y; Wang, X	1
Kim, JH; Kim, SH; Kwon, HY; Lee, JY; Nam, MH; Ryu, DH; Shim, BS	1
Boumber, Y; Chaudhary, S; Kesari, K; Khan, H; Khan, M; Smith, S; Wahab, A	1
Chen, JL; Hu, X; Li, QY; Li, YL; Rao, MJ; Wu, LW; Yan, W; Zhang, B; Zhang, C; Zhang, NY	1
Li, L; Liu, W; Meng, L; Wang, Y; Wang, Z; Yan, H; Zhang, H	1
Chang, SS; Chao, TI; Chen, KF; Chen, LJ; Hsiao, YJ; Hsieh, FS; Huang, CY; Hung, MH; Kuo, CW; Shih, CT; Tsai, MH	1
Qian, HL; Xu, S; Zhu, LZ	1
Cao, H; Ding, W; Li, C; Li, W; Liu, R; Lu, L; Shao, G; Song, J; Wang, J; Xiang, H; Yang, J; Yang, Z	1
He, XH; Huang, HZ; Li, GD; Li, WT; Wang, GZ; Wang, Y; Wang, YH; Wei, N; Xu, LC; Zhang, B	1
Chen, DL; Chen, Y; Guo, XX; Jiang, R; Li, DY; Li, J; Li, XP; Lyu, XT; Lyu, YW; Ran, JH; Tian, K; Yuan, DZ; Zhou, P	1
Chao, D; Liu, K; Pang, L; Shi, Y; Wang, W	1
Deng, JD; Hu, XL; Jiang, Y; Lei, S; Tan, W; Wang, Z; Wen, HX; Zhang, HH	1
Bascal, Z; Caine, M; Czuczman, P; Garcia, P; Hagan, A; Kilpatrick, H; Lewis, AL; Lloyd, AW; Macfarlane, WM; Phillips, G; Press, C; Tang, Y	1
Kim, I; Kim, SY; Namgung, Y	1
Ge, K; Jia, C; Lu, J; Zhu, H	1
Baumert, TF; Duong, FH; Durand, SC; Fofana, I; Heim, MH; Lupberger, J; Pessaux, P; Thumann, C; Xiao, F; Zeisel, MB; Zona, L	1
Biasco, G; Brandi, G; Dika, E; Maibach, H; Patrizi, A; Venturi, M	1
Farghaly, TA; Mahmoud, HK	1
Abbruzzese, JL; Carlson, P; Fogelman, DR; George, B; Javle, M; Khalil, MA; Overman, M; Qiao, W; Varadhachary, G; Wolff, RA	1
Bian, L; Jiang, Z; Wang, T; Zhang, S	1
Aoudjehane, L; Clapéron, A; Conti, F; Desbois-Mouthon, C; Firrincieli, D; Fouassier, L; Ho-Bouldoires, TH; Housset, C; Merabtene, F; Mergey, M; Prignon, A; Scatton, O; Wendum, D	1
Azria, D; Braccini, AL; Ferrero, JM; Jacot, W; Romieu, G; Thezenas, S	1
Cheng, AL; Chiou, TJ; Hsu, C; Hsu, CH; Jin, K; Kang, YK; Sandoval-Tan, J; Shao, YY; Shun, CT; Su, WC; Yang, TS	1
Ohkawa, S; Sakamoto, Y; Ueno, M	1
Aisner, DL; Berge, EM; Doebele, RC	1
Korovina, IaV; Nasyrov, AR; Pirtskhalava, TL	1
Chen, CH; Chen, LC; Chen, YJ; Chien, PH; Chien, YF; Hsieh, YL; Hsu, SC; Huang, WC; Hung, CM; Lin, YM; Tu, CY	1
Baudin, E; Bonichon, F; Borget, I; Brassard, M; Chougnet, CN; Claude-Desroches, M; de la Fouchardière, C; Do Cao, C; Giraudet, AL; Leboulleux, S; Massicotte, MH; Schlumberger, M	1
Dong, X; He, C; Jiang, H; Jiang, X; Ma, L; Pan, S; Qiao, H; Sun, X; Tan, G; Wei, Z; Zhai, B; Zhao, D	1
Edling, CE; Falasca, M; Ghonaim, R; Maffucci, T; Selvaggi, F	1
Bader, AG; Kelnar, K; Zhao, J	1
Bardeesy, N; Caravan, P; Chen, X; Crenshaw, A; DePeralta, DK; Fuchs, BC; Fujii, T; Golub, TR; Gupta, S; Hoshida, Y; Kuroda, T; Lanuti, M; Lauwers, GY; McGinn, CM; Onofrio, R; Schmitt, AD; Tanabe, KK; Taylor, B; Wei, L; Winckler, W; Yamada, S	1
Geissler, M; Steins, M; Thomas, M	2
Dong, JZ; Lu, MQ; Wang, LP; Zhang, SN; Zou, ZL	1
Fuchs, BC; Hoshida, Y; Tanabe, KK	1
Amore, E; Azzolina, A; Bondì, ML; Botto, C; Cervello, M; Craparo, EF; Giammona, G	1
Dong, CS; Li, JH; Liu, QL; Liu, RJ; Luo, BH; Luo, GQ; Wang, JP; Wang, KS; Wen, JF; Xiao, H; Xiao, N; Xie, B; Xiong, F; Yang, XJ; Zhong, M	1
Chen, YJ; Chi, CW; Huang, HL; Su, WC	1
Casey, PJ; Go, ML; Guo, D; Lau, HY; Ramanujulu, PM; Wang, M; Wirawan, M; Yang, T	1
Chao, TT; Chen, KF; Chen, YL; Chu, PY; Hung, MH; Liu, CY; Shiau, CW; Wang, CY; Yu, HC	1
Liao, H; Liu, Y; You, Z; Zahng, J	1
Song, Z; Wu, W; Zhang, Y	1
Huang, MD; Huang, Q; Liu, JY; Xue, JP; Zhang, FL	1
Cui, A; Hou, J; Hua, H; Jiang, Y; Luo, T; Song, P	1
Bruix, J; Carrilho, FJ; Evans, TR; Jensen, M; Kang, YK; Leberre, MA; Llovet, JM; Meinhardt, G; Qin, S; Rosmorduc, O; Ross, PJ; Santoro, A; Thuluvath, PJ; Zhu, AX	1
Chu, JH; Cui, SX; Qu, XJ; Song, ZY; Zhang, YS	1
Bregni, G; de Braud, F; Di Cosimo, S; Galli, G; Gevorgyan, A; Porcu, L; Serpico, D; Tessari, A; Torri, V	1
Bartsch, R; Bergen, ES; Berghoff, AS; Preusser, M; Rudas, M	1
Chang, WA; Chong, IW; Chou, SH; Huang, MS; Hung, JY; Kuo, TY; Lee, JY; Liu, TC; Shen, CH; Tsai, MJ; Wu, KL; Yang, CJ; Yen, CJ	1
Hu, HG; Huang, JJ; Shen, H; Zhao, J	1
Choi, SJ; Gu, HR; Han, CJ; Jeong, JH; Kim, J; Kim, YC; Kim, YJ; Lee, JC; No, SH; Noh, GY; Park, SC; Yang, KY	1
Carella, N; Carr, BI; Cavallini, A; D'Alessandro, R; Lippolis, C; Messa, C; Refolo, MG	1
Bidard, FC; Cottu, P; Escalup, L; Lim, R; Mariani, P; Ng, CK; Norton, L; Pierga, JY; Piscuoglio, S; Reis-Filho, JS; Reyal, F; Sakr, RA; Servois, V; Sigal, B; Vincent-Salomon, A; Wang, L; Weigelt, B	1
Aprile, G; Cardellino, GG; Foltran, L; Macerelli, M; Mazzer, M	1
Bae, JS; Choi, YS; Lee, SH; Lee, YM; Oh, SY; Seok, JY	1
Bandai, Y; Ijichi, M; Kusaka, K; Sakata, H; Shibasaki, M; Tanabe, A; Toda, T	1
Fu, F; Geng, J; Sun, D; Wang, H; Xie, X; Yu, G; Zhang, L	1
Agerbaek, M; Cerbone, L; Collette, S; Daugaard, G; Marreaud, S; Sengeløv, L; Sternberg, CN; Van Herpen, C; Zhang, J	1
Bonnefoi, H; Grellety, T; Italiano, A; Robert, J; Soubeyran, I	1
Ali, HR; Bentley, D; Caldas, C; Chin, SF; Contente-Cuomo, T; Dawson, SJ; Farahani, H; Gale, D; Grant, J; Humphray, S; Kingsbury, Z; Marass, F; Murtaza, M; Pogrebniak, K; Provenzano, E; Rosenfeld, N; Rueda, OM; Shah, P; Shah, SP; Shumansky, K; Tsui, DWY; Wallis, M	1
Chen, JY; Chen, WS; Chen, YJ; Huang, WC; Yen, CJ	1
Chen, M; He, Q; Luo, P; Peng, X; Shao, J; Xu, L; Xu, Z; Yang, B; Zhu, H; Zhu, Y	1
Chen, KF; Chen, YL; Chu, PY; Hung, MH; Shiau, CW; Shih, CT; Tai, WT; Yu, HC	1
Chen, C; Lian, ZZ; Sun, YF	1
Sun, J; Zhan, C; Zhang, Y; Zhao, H; Zhao, L	1
Ajgal, Z; Alexandre, J; Arrondeau, J; Goldwasser, F; Huillard, O; Hulin, A; Lavaud, P; Rousseau, B	1
Chen, C; Cheng, L; Fan, L; Hu, T; Lu, J; Lu, X; Ma, Y; Ni, B; Ou, S; Qi, F; Yi, X; Yu, L; Zhang, C; Zhao, C; Zheng, Z	1
Li, J; Liu, Z; Lu, D; Wang, H; Wang, J; Wei, X; Xie, H; Xu, X; Zheng, S; Zhuang, R	1
Liu, Q; Liu, Y; Luo, F; Shi, L; Yang, F; Zhang, F; Zou, M	1
Huang, XX; Mao, SS; Wu, JS; Xiong, J; Yu, XN	1
Wu, YL; Xu, CR; Yang, JJ; Zhang, XC; Zhong, WZ; Zhou, Q	1
Hsu, FT; Pan, PJ; Tsai, JJ	1
Chen, L; Gonzalez, FJ; Gu, J; Hu, CL; Hu, L; Li, L; Li, S; Lin, XM; Liu, JF; Tang, J; Wang, HY; Wang, RY; Wu, MC; Yan, XZ; Zhang, BH; Zhou, WP; Zhu, YJ	1
Czuczman, P; Hagan, A; Lewis, AL; Lloyd, AW; Macfarlane, WM; Phillips, GJ	1
Ji, L; Liang, T; Shen, Y; Shi, L; Xu, L; Yang, F; Zhang, G; Zhu, F	1
Ellison, K; Hirsch, FR; Kim, J; Mitsudomi, T; Murakami, I; Rivard, CJ; Suda, K; Yu, H	1
Han, X; Peng, JY; Qi, Y; Wang, XN; Xu, LN; Xu, YW; Yin, LH	1
Li, JR; Li, LY; Wang, MZ; Wang, SL; Zhang, L; Zhang, XT; Zhong, W	1
Bertran, E; Caja, L; Carmona-Cuenca, I; Fabregat, I; Murillo, MM; Sancho, P	1
Abbruzzese, J; Chadha, R; Davila, M; Glover, K; Iwasaki, M; Kaseb, A; Kaur, H; Lin, E; Morris, JS; Thomas, MB	1
Denzlinger, C; Hass, HG	1
Belani, CP; Dancey, J; Gandara, DR; Gandour-Edwards, R; Iqbal, S; Kindler, HL; Lenz, HJ; Longmate, J; Lurje, G; Mack, PC; Ramanathan, RK; Singh, DA; Tanaka, M; Yen, Y	1
Beau-Faller, M; Gaub, MP; Guerin, E; Jeung, MY; Legrain, M; Mennecier, B; Molard, A; Neuville, A; Oudet, P; Quoix, E; Ruppert, AM; Voegeli, AC	1
Dreyer, C; Faivre, S; Raymond, E	1
Finn, RS; Zhu, AX	1
Demetter, P; Geurs, F; Knape, S; Ponette, J; Ponette, S; Vandewaeter, S	1
Chang, CH; Chang, JW; Hui, CY; Yang, CH	1
Arai, S; Fukui, T; Hataishi, R; Iwasaki, M; Katagiri, M; Katono, K; Kobayashi, H; Kubota, M; Masuda, N; Mitsufuji, H; Nishii, Y; Onoda, S; Otani, S; Ryuge, S; Takakura, A; Wada, M; Yamamoto, M; Yanaihara, T; Yanase, N; Yokoba, M	1
Baron, A; Bladt, F; Blivet-Van Eggelpoël, MJ; Desbois-Mouthon, C; Fartoux, L; Housset, C; Rosmorduc, O; Venot, C	1
Balint, C; Bekaii-Saab, T; Campbell, A; Chen, H; Culler, K; Dai, Z; Dancey, J; Eng, C; Grever, M; Heerema, N; Lee, RM; Markowitz, J; O'Neil, B; Papp, A; Prescott, N; Sadee, W; Villalona-Calero, M; Wei, L; Zalupski, M	1
Aihara, A; Arii, S; Ito, K; Kudo, A; Matsumura, S; Mitsunori, Y; Murakata, A; Nakamura, N; Noguchi, N; Tanaka, S; Yasen, M	1
Cercueil, JP; Chauffert, B; Ghiringhelli, F; Guiu, B; Khouri, C; Ladoire, S	1
Chen, W; Chen, WC; Hsia, TC; Lai, HC; Shih, CM; Tseng, GC	1
Fukuoka, M; Nakagawa, K; Okamoto, I; Takeda, M	1
Gao, HJ; Guo, WF; Li, JJ; Li, XY; Liu, B; Liu, XQ; Qu, LL; Tang, CH; Wang, WW; Wang, WX	1
Li, X; Li, Z; Lv, Y; Ma, Y; Yi, S; Yuan, A	1
Al-Din, ES; El-Sabbagh, OI; Kadry, HH; Shabaan, MA	1
Alam, N; Dudek, AZ; Gustafson, KS; Kapoor, A; Ladanyi, M; Truskinovsky, AM; Zakowski, MF	1
Hagymási, K; Tulassay, Z	1
Bertran, E; Caja, L; Campbell, J; Fabregat, I; Fausto, N	1
Guan, ZZ; Guo, GF; Wan, DS; Wu, PH; Xia, JC; Xia, LP; Zeng, YX; Zhang, B	1
Azzariti, A; Colucci, G; Fratto, ME; Galluzzo, S; Maiello, E; Santini, D; Silvestris, N; Tommasi, S; Tonini, G; Vincenzi, B; Zoccoli, A	1
Carducci, M; Dancey, J; Donehower, RC; Hidalgo, M; Iacobuzio-Donahue, C; Jacene, H; Jimeno, A; Kahn, Y; Kulesza, P; Laheru, DA; Messersmith, WA; Rudek, MA; Spira, A; Zhao, M	1
Chung, YH; Kim, KH; Kim, KM; Lee, D; Lee, HC; Lee, SG; Lee, YJ; Lee, YS; Lim, YS; Park, YK; Shim, JH; Suh, DJ	1
Morioka, T; Niikura, N; Okamura, T; Saito, Y; Suzuki, Y; Terada, M; Terao, M; Tokuda, Y; Tsuda, B	1
Chang, CS; Chao, DC; Ho, TY; Hsiang, CY; Huang, HC; Kao, ST; Liang, JA; Lin, LJ; Wu, SL	1
Gu, FY; Hu, XY; Li, MD; Shen, H; Yuan, Y; Zhong, X	1
Alberts, SR; Dakhil, SR; Fitch, TR; Gross, HM; Kim, GP; Morlan, BW; Nair, S	1
Budak, K; Pestalozzi, B; Weisshaupt, Ch	1
Dennie, T; Holen, KD; Mohammed, TA	1
Bertran, E; Caja, L; Campbell, JS; Fabregat, I; Fausto, N; Ortiz, C; Sancho, P	1
Erlichman, C; Flynn, PJ; Holen, KD; Mahoney, MR; Northfelt, DW; Philip, PA; Picus, J; Pitot, HC	1
Bodzin, AS; Doria, C; Gu, T; Hurtt, R; Wei, Z	1
Chen, CH; Hsu, WM; Hu, RH; Huang, HC; Huang, J; Huang, MC; Huang, MJ; Lai, HS; Lee, JJ; Lee, PH; Liu, CH; Wu, YM	1
Chen, L; Gu, J; Liu, H; Sun, L; Wang, S; Wen, Y; Xu, J; Yun, X; Zhou, L	1
Düwel, P; Gehl, HB; Görner, M; Hirnle, P; Müller, F; Riesenberg, H	1
Buck, E; Desai, V; Epstein, DM; Miglarese, M; Wang, J; Zhao, H	1
Ishiba, T; Kuwayama, T; Nakagawa, T; Oda, G; Sato, T; Sugihara, K; Sugimoto, H	1
Bufill, JA; Chiorean, EG; Coleman, N; Currie, C; Johnston, EL; Loehrer, PJ; Picus, J; Ramasubbaiah, R; Tong, Y; Yu, M	1
Chao, Y; Cheng, AL; Hsieh, RK; Hsieh, TY; Hsu, C; Huang, WT; Huo, TI; Hwang, WS; Meng, R; Yang, TS; Yu, CW	1
Berger, W; Grasl-Kraupp, B; Grunt, T; Grusch, M; Holzmann, K; Koppensteiner, H; Krupitza, G; Lackner, A; Losert, A; Lötsch, D; Marian, B; Peter-Vörösmarty, B; Schmid, K; Schulte-Hermann, R; Steiner, E	1
Abbruzzese, JL; Deaton, FL; Garrett-Mayer, E; Hassabo, HM; Hassan, MM; Iwasaki, M; Kaseb, AO; Lin, E; Morris, JS; Onicescu, G; Thomas, MB; Xiao, L	1
Chan, P; Cheung, TT; Fan, ST; Pang, R; Poon, RT; Wong, H; Yao, TJ; Yau, T	1
Aiba, S; Fujimura, T; Haga, T; Hashimoto, A; Hidaka, T; Mizuashi, M; Onami, K; Watabe, A	1
Abe, M; Hashimoto, O; Inoue, K; Iwamoto, H; Koga, H; Masuda, H; Nakamura, T; Sata, M; Torimura, T; Ueno, T; Yano, H	1
Baird, RD; Barton, DP; Kaye, SB; Khan, AZ; Moreno, V; Vitfell-Pedersen, J; Yap, TA	1
Dauser, B; Dienes, HP; Dufour, JF; Hayden, H; Peck-Radosavljevic, M; Piguet, AC; Pinter, M; Prager, G; Rohr-Udilova, N; Sieghart, W	1
Govindarajan, R; Makhoul, I; Siegel, E; Williamson, S	1
Abou-Alfa, GK; Ang, C; O'Reilly, EM	1
Aasrum, M; Christoffersen, T; Dajani, O; Guren, T; Müller, KM; Sandnes, D; Tveteraas, IH; Ødegård, J	1
Antoine, M; Blons, H; Buisine, MP; Cadranel, J; Chetaille, B; Chouaid, C; Coudert, B; Daniel, C; Danton, G; De Fraipont, F; Faller, M; Foucher, P; Lacroix, L; Longchampt, E; Mauguen, A; Michiels, S; Morin, F; Pignon, JP; Poulot, V; Quoix, E; Solassol, J; Urban, T; Westeel, V; Wislez, M; Zalcman, G	1
Chen, J; Dassarath, M; Gu, R; Wang, Q; Wu, G; Yang, K; Yin, Z	1
Cserepes T, M; Döme, B; Rényi-Vámos, F; Török, S	1
Cai, X; Cao, P; Hu, C; Lu, W; Xu, X; Yang, J; Yu, Q	1
Arma, D; Balabaud, C; Bexiga, MG; Bioulac-Sage, P; Blanc, JF; Castain, C; Chevet, E; Higa, A; Le Bail, B; Marza, E; Rosenbaum, J; Simpson, JC; Taouji, S; Yi, P	1
Chang, YL; Chen, HJ; Chen, KF; Cheng, AL; Liu, CY; Shiau, CW; Yu, HC	1
Chang, AY; Wang, M	1
Horiguchi, N; Kakizaki, S; Mori, M; Nakajima, Y; Sato, K; Sunaga, N; Takagi, H	1
Chen, XG; Gao, XQ; Jin, J; Wang, YK; Xu, BL; Zhang, Y; Zhu, LN	1
Amano, S; Enomoto, K; Fujisaki, S; Hara, Y; Hirano, T; Maeda, T; Nagashima, S; Sakurai, K; Suzuki, S; Tomita, R	1
Abrams, TA; Ancukiewicz, M; Bhargava, P; Blaszkowsky, LS; Duda, DG; Fuchs, CS; Jain, RK; Knowles, M; McCleary, NJ; Meyerhardt, JA; Muzikansky, A; Regan, E; Ryan, DP; Sahani, DV; Sheehan, S; Supko, JG; Vasudev, E; Zhu, AX	1
Aguirre Ghiso, J; Estrada, Y; Liu, D; Ossowski, L	1
Elomaa, I; Joensuu, H; Orpana, A; Osterlund, P; Repo, H	1
Fishman, AD; Wadler, S	1
Binetti, P; La Cesa, A; Massacesi, C; Picardi, A; Santini, D; Tonini, G; Vincenzi, B	1
Glimelius, B	1
Matsuo, M; Saiki, I; Sakurai, H	1
Gill, S; Goldberg, RM; Thomas, RR	1
Hao, LH; Li, X; Li, Y; Xu, JM; Yuan, SJ; Zhao, QC; Zhu, BD	1
Alper, R; Ilan, Y; Nagler, A; Ohana, M; Pines, M; Shapira, MY; Shibolet, O; Vlodavsky, I	1
Amano, H; Hoshi, S; Kono, C; Yamada, Y; Yamaguchi, T	1
Chau, I; Cunningham, D; Hill, M; Katopodis, R; Middleton, G; Norman, AR; Oates, JR; Ross, PJ; Stewart, G; Topham, C; Waters, JS	1
Chambers, AF; Ellis, CG; Groom, AC; MacDonald, IC; Mackenzie, LT; Ryan, A; Varghese, HJ	1
Bjarnason, GA; Charpentier, D; Dent, S; Douglas, L; Goel, R; Matthews, S; Seymour, L; Walsh, W; Winquist, E; Wong, R	1
Höpfner, M; Huether, A; Scherübl, H; Schuppan, D; Sutter, AP; Zeitz, M	1
Amoroso, V; Ferrari, VD; Fusi, A; Mambrini, A; Marini, G; Marpicati, P; Montini, E; Rangoni, G; Simoncini, E; Valcamonico, F; Vasalli, L	1
Barbu, V; Cacheux, W; Clergue, F; Desbois-Mouthon, C; Housset, C; Poupon, R; Rey, C; Rosmorduc, O; Schiffer, E; Wendum, D	1
Li, X; Li, Y; Lu, QY; Yuan, SJ; Zhao, QC; Zhu, BD	1
Jeng, YM; Lien, HC; Su, MC	1
Höpfner, M; Huether, A; Scherübl, H; Schuppan, D; Sutter, AP	1
Friberg, G; Kindler, HL; Skoog, L; Vokes, EE; Wade-Oliver, K	1
Chu, DT; Guan, ZZ; Jiang, GL; Li, LY; Li, W; Liu, XY; Zhang, L; Zhao, HY	1
Allmer, C; Donehower, RC; Erlichman, C; Fitch, T; Kim, G; Mahoney, MR; Philip, PA; Picus, J; Pitot, HC; Thomas, J	1
Baradari, V; Höpfner, M; Huether, A; Scherübl, H; Schuppan, D	1
Antonaci, S; Azzariti, A; Giannelli, G; Paradiso, A; Porcelli, L; Sgarra, C	2
Goto, H; Imao, M; Kato, T; Nakashima, M; Sano, K; Yasuda, S; Yoshimura, K	1
Matsuo, M; Ohtani, O; Saiki, I; Sakurai, H; Ueno, Y	1
Greten, TF	1
Matsumoto, K; Murawaki, Y; Nagahara, T; Okano, J	1
Bartralot, R; Bodet, D; García-Patos, V; Heras, C; Mollet, J	1
Li, JQ; Lin, XJ; Xu, L; Zhang, YJ	1
Bièche, I; Blanc, JF; Dugot-Senant, N; Laurendeau, I; Pines, M; Rosenbaum, J; Rullier, A; Taras, D	1
Avila, MA; Berasain, C; Castillo, J; Erroba, E; Lee, DC; Perugorría, MJ; Prieto, J; Santamaría, M	1
Chen, H; Fan, ST; Kok, TW; Liu, Y; Poon, RT; Shao, W; Sun, X	1
Baradari, V; Hopfner, M; Huether, A; Scherubl, H; Schuppan, D; Sutter, AP	1
Clendeninn, N; Dancey, J; Hamburg, S; Hochster, H; Jhawer, M; Mani, S; Rosen, L; Tempero, M	1
Barbu, V; Blivet-Van Eggelpoël, MJ; Cacheux, W; Desbois-Mouthon, C; Fartoux, L; Housset, C; Poupon, R; Rosmorduc, O	1
Giaccone, G; Hoekman, K; Kater, M; Manoliu, RA; Meijerink, MR; van Cruijsen, H; van Schaik, C; van Waesberghe, JH	1
Desbois-Mouthon, C; Fartoux, L; Poupon, R; Rosmorduc, O	1
Fujiwara, M; Ikehara, S; Ikehara, Y; Kodera, Y; Koike, M; Mochizuki, Y; Nakanishi, H; Nakao, A; Tatematsu, M; Yatabe, Y; Yokoyama, H	1
Guo, F; Letrent, SP; Sharma, A	1
Akie, K; Asahina, H; Dosaka-Akita, H; Harada, M; Ishida, T; Isobe, H; Kinoshita, I; Konishi, J; Munakata, M; Nishimura, M; Ogura, S; Sukoh, N; Yamazaki, K; Yokouchi, H	1
Bragg, J; Pomeranz, MK	1
Abbruzzese, JL; Brown, T; Chadha, R; Dancey, J; Glover, K; Morris, J; Rashid, A; Thomas, MB; Wang, X	1
Jänne, PA; Liu, W; Makrauer, FL; Odze, RD; Qamar, AA	1
Croitoru, A; Feld, R; Feun, L; Gallo, J; Gish, RG; Jeziorski, K; Kennealey, GT; Lazar, L; Leighton, J; Porta, C; Ruff, P	1
Aasrum, M; Christoffersen, T; Dajani, OF; Guren, TK; Lilleby, P; Meisdalen, K; Sandnes, D; Thoresen, GH; Tveteraas, IH	1
Boeck, S; Heinemann, V; Wollenberg, A	1
Blaszkowsky, LS; Clark, JW; Enzinger, PC; Fuchs, CS; Kulke, MH; Kwak, EL; Lawrence, C; Meyerhardt, JA; Muzikansky, A; Ryan, DP; Zhu, AX	1
Zhu, AX	1
O'Neil, BH; Venook, AP	1
Biagi, JJ; Cripps, C; Eisenhauer, E; Feld, R; Gill, S; Knox, JJ; Major, P; Seymour, L; Synold, TW; Wainman, N	1
Chen, L; Zhang, PL	1
Belluco, C; Deng, J; Espina, V; Esserman, LJ; Laird, J; Liotta, LA; Mammano, E; Nitti, D; Petricoin, EF; Pierobon, M; Speer, R; Swain, SM; Wulfkuhle, JD; Yang, SX	1
Brueckl, WM; Hahn, EG; Murray, S; Schoeberl, A; Wiest, GH; Wirtz, RM	1
Barutca, S; Bolaman, Z; Kadikoylu, G; Meydan, N; Yavasoglu, I	1
Dorfman, JD; Fuchs, BC; Fujii, T; Goodwin, JM; Lanuti, M; Tanabe, KK; Zhu, AX	1
Allegra, CJ	1
Stott, WT	1
Adenis, A; Carr, BI; Ducreux, M; François, E; Kerr, D; Rougier, P; Seymour, L	1
Bauer, B; Benter, T; Daniel, PT; Dietz, R; Dörken, B; Friedrich, M; Köhne, CH; Kretzschmar, A; Thuss-Patience, P	1
Clendennin, N; Johnston, A; Rudy, J; Stuart, K; Tessitore, J	1
Chak, K; Chan, AT; Chao, Y; Huang, A; Johnson, P; Johnston, A; Lee, SD; Leung, TW; Lui, MC; Mok, TS; Yeo, W	1
Dorko, K; Esplen, JE; Jo, M; Michalopoulos, GK; Stolz, DB; Strom, SC	1
Arvelo, F; Bras-Gonçalves, RA; Coquelle, A; De Pinieux, G; Dutrillaux, B; Formento, JL; Lesuffleur, T; Milano, G; Pandrea, I; Pocard, M; Poirson-Bichat, F; Poupon, MF; Ronco, G; Villa, P	1
Ganser, A; Reinke, F; Schlichting, C; Schöffski, P; van Gennip, AH; van Kuilenburg, AB; Volk, J	1
Boige, V; Ducreux, M; Taïeb, J	1
Kosmas, C; Koufos, C; Tsavaris, N; Vadiaka, M	1
Carey, RW; Clamon, GH; Costanza, ME; Dawson, NA; Korzun, AH; Norton, L; Pollak, M; Vogelzang, NJ	1
Balinska, M; Bunni, M; Galivan, J; Maley, F; Maley, GF; Priest, DG; Rhee, MS	1
Buamah, PK; Cornell, C; Harris, AL; James, OF; Skillen, AW	1
Buamah, PK; Harris, AL; James, OF; Skillen, AW	1
Bassendine, MF; Curtin, NJ; Harris, AL; James, OF; Loose, H	1
Buamah, PK; Cassells-Smith, AJ; Harris, AL; James, OF; Skillen, AW	1
Eisenhauer, EA; Pater, JL; Walsh, WR; Zee, BC	1
Bassendine, MF; Curtin, NJ; Harris, AL; James, OF	1
Bennett, M; Buamah, PK; James, OF; Lendrum, R; McArdle, P	1
Maley, F; Maley, GF	1

Reviews

15 review(s) available for quinazolines and Cancer of Liver

Article	Year
Erlotinib. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 2014, Volume: 201 Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Erlotinib Hydrochloride; Humans; Liver Neoplasms; Lung Neoplasms; Pancreatic Neoplasms; Protein Kinase Inhibitors; Quinazolines	2014
Erlotinib-associated interstitial lung disease in advanced pancreatic carcinoma: a case report and literature review. Tumori, 2015, Jul-24, Volume: 101, Issue:4 Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Autopsy; Critical Care; Diagnosis, Differential; Erlotinib Hydrochloride; Fatal Outcome; Humans; Liver Neoplasms; Lung Diseases, Interstitial; Lymphatic Metastasis; Male; Pancreatic Neoplasms; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pulmonary Alveoli; Quinazolines; Tomography, X-Ray Computed	2015
[Targeted therapies and their indications in solid neoplasias]. La Revue de medecine interne, 2009, Volume: 30, Issue:5 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Bevacizumab; ErbB Receptors; Erlotinib Hydrochloride; Everolimus; Gefitinib; Humans; Indoles; Kidney Neoplasms; Liver Neoplasms; Neoplasms; Niacinamide; Phenylurea Compounds; Pyridines; Pyrroles; Quinazolines; Receptor, ErbB-2; Receptors, Vascular Endothelial Growth Factor; Sirolimus; Sorafenib; Sunitinib; Vascular Endothelial Growth Factor A	2009
Targeting angiogenesis in hepatocellular carcinoma: focus on VEGF and bevacizumab. Expert review of anticancer therapy, 2009, Volume: 9, Issue:4 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Carcinoma, Hepatocellular; Clinical Trials as Topic; Cytotoxins; Deoxycytidine; Erlotinib Hydrochloride; Fluorouracil; Gemcitabine; Humans; Liver Neoplasms; Neoplasm Proteins; Neovascularization, Pathologic; Organoplatinum Compounds; Oxaliplatin; Purines; Quinazolines; RNA, Small Interfering; Treatment Outcome; Vascular Endothelial Growth Factor A	2009
Erlotinib. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 2010, Volume: 184 Topics: Animals; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; ErbB Receptors; Erlotinib Hydrochloride; Humans; Liver Neoplasms; Lung Neoplasms; Neoplasms; Pancreatic Neoplasms; Protein Kinase Inhibitors; Quinazolines	2010
[New possibilities of targeted therapy in the treatment of hepatocellular carcinoma with the help of molecular biology]. Orvosi hetilap, 2010, Oct-24, Volume: 151, Issue:43 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzenesulfonates; Bevacizumab; Biomarkers, Tumor; Carcinoma, Hepatocellular; Catheter Ablation; Cell Cycle; Chemoembolization, Therapeutic; Chemotherapy, Adjuvant; Epigenesis, Genetic; ErbB Receptors; Erlotinib Hydrochloride; Gene Expression Regulation, Neoplastic; Hepatectomy; Humans; Indoles; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Niacinamide; Phenylurea Compounds; Proteasome Endopeptidase Complex; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyridines; Pyrroles; Quinazolines; Signal Transduction; Sirolimus; Sorafenib; Sunitinib; TOR Serine-Threonine Kinases; Vascular Endothelial Growth Factor A; Wnt Proteins	2010
Targeting EGFR in bilio-pancreatic and liver carcinoma. Frontiers in bioscience (Scholar edition), 2011, 01-01, Volume: 3, Issue:1 Topics: Antibodies, Monoclonal; Antineoplastic Agents; Benzenesulfonates; Biliary Tract Neoplasms; Carcinoma; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; Humans; Liver Neoplasms; Niacinamide; Pancreatic Neoplasms; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Quinazolines; Randomized Controlled Trials as Topic; Sorafenib	2011
Targeted agents and systemic therapy in hepatocellular carcinoma. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 2013, Volume: 190 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Benzenesulfonates; Carcinoma, Hepatocellular; ErbB Receptors; Erlotinib Hydrochloride; Humans; Immunotherapy; Liver Neoplasms; Molecular Targeted Therapy; Neovascularization, Pathologic; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Quinazolines; Sorafenib; Vascular Endothelial Growth Factor A	2013
[Nintedanib (BIBF 1120) in the treatment of solid cancers: an overview of biological and clinical aspects]. Magyar onkologia, 2012, Volume: 56, Issue:3 Topics: Animals; Antineoplastic Agents; Axitinib; Benzenesulfonates; Carcinoma, Hepatocellular; Clinical Trials as Topic; Colorectal Neoplasms; Digestive System; Enzyme Inhibitors; Female; Genital Neoplasms, Female; Humans; Imidazoles; Indazoles; Indoles; Liver Neoplasms; Lung Neoplasms; Male; Neoplasms; Niacinamide; Oligonucleotides; Phenylurea Compounds; Phthalazines; Piperidines; Prostatic Neoplasms; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Quinazolines; Receptors, Fibroblast Growth Factor; Receptors, Platelet-Derived Growth Factor; Receptors, Vascular Endothelial Growth Factor; Signal Transduction; Sorafenib; Sulfonamides; Xenograft Model Antitumor Assays	2012
Advances in the treatment of metastatic colorectal cancer. Clinical colorectal cancer, 2001, Volume: 1, Issue:1 Topics: Administration, Oral; Antibodies, Monoclonal; Antineoplastic Agents; Camptothecin; Cancer Vaccines; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Drug Administration Schedule; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Prodrugs; Quinazolines; Randomized Controlled Trials as Topic; Thiophenes; Uracil	2001
Palliative treatment of patients with colorectal cancer. Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society, 2003, Volume: 92, Issue:1 Topics: Antimetabolites, Antineoplastic; Camptothecin; Colorectal Neoplasms; Disease Progression; Enzyme Inhibitors; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Palliative Care; Quinazolines; Survival Analysis; Tegafur; Thiophenes; Thymidylate Synthase; Topoisomerase I Inhibitors; Treatment Outcome; Uracil	2003
Review article: colorectal cancer chemotherapy. Alimentary pharmacology & therapeutics, 2003, Oct-01, Volume: 18, Issue:7 Topics: Antineoplastic Agents; Camptothecin; Chemotherapy, Adjuvant; Clinical Trials as Topic; Colorectal Neoplasms; Drug Design; Floxuridine; Fluorouracil; Forecasting; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin; Pyrimidines; Quinazolines; Thiophenes	2003
[Anti-EGFR therapy: towards a "à la carte" targeting of hepatocellular carcinoma]. Gastroenterologie clinique et biologique, 2006, Volume: 30, Issue:10 Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cetuximab; Clinical Trials, Phase II as Topic; Disease Models, Animal; Epidermal Growth Factor; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; Humans; Ligands; Liver Neoplasms; Multicenter Studies as Topic; Neoplasm Recurrence, Local; Protein Kinase Inhibitors; Quinazolines; Rats; Signal Transduction; Transforming Growth Factor alpha	2006
Hepatocellular carcinoma: the role of the North American GI Steering Committee Hepatobiliary Task Force and the advent of effective drug therapy. The oncologist, 2007, Volume: 12, Issue:12 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Bevacizumab; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Combined Modality Therapy; Erlotinib Hydrochloride; Humans; Liver Neoplasms; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Quinazolines; Sorafenib	2007
[The new chemotherapy of colorectal cancers]. Presse medicale (Paris, France : 1983), 2002, Jan-26, Volume: 31, Issue:3 Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Capecitabine; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Colorectal Neoplasms; Combined Modality Therapy; Deoxycytidine; Drug Therapy, Combination; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin; Postoperative Care; Prodrugs; Quinazolines; Randomized Controlled Trials as Topic; Thiophenes; Time Factors	2002

Trials

40 trial(s) available for quinazolines and Cancer of Liver

Article	Year
First-in-Human Phase I Study of Fisogatinib (BLU-554) Validates Aberrant FGF19 Signaling as a Driver Event in Hepatocellular Carcinoma. Cancer discovery, 2019, Volume: 9, Issue:12 Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Drug Administration Schedule; Female; Fibroblast Growth Factors; Humans; Liver Neoplasms; Male; Middle Aged; Pyrans; Quinazolines; Receptor, Fibroblast Growth Factor, Type 4; Signal Transduction; Treatment Outcome; Young Adult	2019
Hepatic arterial infusion of oxaliplatin plus raltitrexed in patients with intermediate and advanced stage hepatocellular carcinoma: A phase II, single-arm, prospective study. European journal of cancer (Oxford, England : 1990), 2020, Volume: 134 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Female; Follow-Up Studies; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Oxaliplatin; Prognosis; Prospective Studies; Quinazolines; Survival Rate; Thiophenes	2020
Trastuzumab plus capecitabine vs. lapatinib plus capecitabine in patients with trastuzumab resistance and taxane-pretreated metastatic breast cancer. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2013, Volume: 34, Issue:5 Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Capecitabine; Deoxycytidine; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Lapatinib; Liver Neoplasms; Lung Neoplasms; Middle Aged; Prospective Studies; Quinazolines; Taxoids; Trastuzumab; Treatment Outcome	2013
Bevacizumab with erlotinib as first-line therapy in Asian patients with advanced hepatocellular carcinoma: a multicenter phase II study. Oncology, 2013, Volume: 85, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Asian People; Bevacizumab; Carcinoma, Hepatocellular; Disease-Free Survival; ErbB Receptors; Erlotinib Hydrochloride; Female; Humans; Liver Neoplasms; Male; Middle Aged; Proto-Oncogene Proteins c-akt; Quinazolines; Treatment Outcome; Vascular Endothelial Growth Factor A	2013
[Effectiveness of combined systemic and regional chemotherapy in treating patients with metastatic colorectal cancer after extrahepatic progression of the disease]. Voprosy onkologii, 2013, Volume: 59, Issue:4 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Cancer, Regional Perfusion; Colorectal Neoplasms; Disease Progression; Doxorubicin; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Leucovorin; Liver Neoplasms; Male; Middle Aged; Mitomycin; Organoplatinum Compounds; Quinazolines; Thiophenes; Treatment Outcome	2013
SEARCH: a phase III, randomized, double-blind, placebo-controlled trial of sorafenib plus erlotinib in patients with advanced hepatocellular carcinoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Feb-20, Volume: 33, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Double-Blind Method; Erlotinib Hydrochloride; Female; Humans; Liver Neoplasms; Male; Middle Aged; Niacinamide; Phenylurea Compounds; Placebos; Quinazolines; Sorafenib	2015
Results from a Phase I Study of Lapatinib with Gemcitabine and Cisplatin in Advanced or Metastatic Bladder Cancer: EORTC Trial 30061. Oncology, 2016, Volume: 90, Issue:1 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Neoplasms; Cisplatin; Deoxycytidine; Dose-Response Relationship, Drug; Drug Administration Schedule; ErbB Receptors; Febrile Neutropenia; Female; Gemcitabine; Humans; International Cooperation; Lapatinib; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Maximum Tolerated Dose; Middle Aged; Quinazolines; Receptor, ErbB-2; Renal Insufficiency; Treatment Outcome; Urinary Bladder Neoplasms	2016
Raltitrexed plus oxaliplatin-based transarterial chemoembolization in patients with unresectable hepatocellular carcinoma. Anti-cancer drugs, 2016, Volume: 27, Issue:7 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Doxorubicin; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Quinazolines; Thiophenes; Young Adult	2016
[Efficacy and safety of gefitinib in maintenance therapy for patients with advanced non-small cell lung cancer]. Zhonghua zhong liu za zhi [Chinese journal of oncology], 2008, Volume: 30, Issue:3 Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Diarrhea; Disease-Free Survival; Exanthema; Female; Gefitinib; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Proportional Hazards Models; Quinazolines; Remission Induction; Smoking; Survival Rate	2008
Phase II trial of the combination of bevacizumab and erlotinib in patients who have advanced hepatocellular carcinoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Feb-20, Volume: 27, Issue:6 Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Carcinoma, Hepatocellular; Drug Therapy, Combination; ErbB Receptors; Erlotinib Hydrochloride; Female; Humans; Liver Neoplasms; Male; Middle Aged; Quinazolines; Vascular Endothelial Growth Factor A	2009
A phase II study of lapatinib in patients with advanced biliary tree and hepatocellular cancer. Cancer chemotherapy and pharmacology, 2009, Volume: 64, Issue:4 Topics: Antineoplastic Agents; Biliary Tract Neoplasms; Carcinoma, Hepatocellular; Humans; Lapatinib; Liver Neoplasms; Quinazolines; Survival Analysis	2009
A multi-institutional phase II study of the efficacy and tolerability of lapatinib in patients with advanced hepatocellular carcinomas. Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Sep-15, Volume: 15, Issue:18 Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Disease Progression; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Lapatinib; Liver Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Predictive Value of Tests; Quinazolines; Survival Rate	2009
[Erlotinib in the treatment of advanced non-small-cell lung cancer (NSCLC)]. Zhonghua zhong liu za zhi [Chinese journal of oncology], 2010, Volume: 32, Issue:2 Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Diarrhea; Disease-Free Survival; ErbB Receptors; Erlotinib Hydrochloride; Exanthema; Female; Follow-Up Studies; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Proportional Hazards Models; Protein Kinase Inhibitors; Quinazolines; Remission Induction; Smoking; Survival Rate	2010
Phase I trial of oxaliplatin, infusional 5-fluorouracil, and leucovorin (FOLFOX4) with erlotinib and bevacizumab in colorectal cancer. Clinical colorectal cancer, 2010, Volume: 9, Issue:5 Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colorectal Neoplasms; Erlotinib Hydrochloride; Female; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Liver Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Organoplatinum Compounds; Quinazolines; Survival Rate; Tissue Distribution; Treatment Outcome	2010
Cediranib (AZD2171) in patients with advanced hepatocellular carcinoma: a phase II North Central Cancer Treatment Group Clinical Trial. American journal of clinical oncology, 2012, Volume: 35, Issue:4 Topics: Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Female; Follow-Up Studies; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Grading; Prognosis; Quinazolines; Survival Rate	2012
Activity of oxaliplatin plus capecitabine (CapeOx) with lapatinib for metastatic colorectal cancer: results from two patients treated on a clinical study. Clinical advances in hematology & oncology : H&O, 2011, Volume: 9, Issue:6 Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Female; Fluorouracil; Humans; Lapatinib; Liver Neoplasms; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Quinazolines	2011
Phase 2 study of bevacizumab plus erlotinib in patients with advanced hepatocellular cancer. Cancer, 2012, May-01, Volume: 118, Issue:9 Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carcinoma, Hepatocellular; Disease-Free Survival; Erlotinib Hydrochloride; Female; Humans; Liver Neoplasms; Male; Middle Aged; Quinazolines; Treatment Outcome	2012
Phase II trial of erlotinib and docetaxel in advanced and refractory hepatocellular and biliary cancers: Hoosier Oncology Group GI06-101. The oncologist, 2012, Volume: 17, Issue:1 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Cadherins; Carcinoma, Hepatocellular; Disease-Free Survival; Docetaxel; Erlotinib Hydrochloride; Female; Humans; Liver Neoplasms; Male; Middle Aged; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Quinazolines; ras Proteins; Taxoids	2012
Vandetanib in patients with inoperable hepatocellular carcinoma: a phase II, randomized, double-blind, placebo-controlled study. Journal of hepatology, 2012, Volume: 56, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Hepatocellular; Double-Blind Method; ErbB Receptors; Female; Humans; Liver Neoplasms; Male; Middle Aged; Piperidines; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Survival Rate; Treatment Outcome	2012
Efficacy of bevacizumab plus erlotinib for advanced hepatocellular carcinoma and predictors of outcome: final results of a phase II trial. Oncology, 2012, Volume: 82, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Angiopoietin-2; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carcinoma, Hepatocellular; Disease-Free Survival; ErbB Receptors; Erlotinib Hydrochloride; Female; Humans; Liver Neoplasms; Male; Middle Aged; Proportional Hazards Models; Quinazolines	2012
Phase II study of bevacizumab and erlotinib in the treatment of advanced hepatocellular carcinoma patients with sorafenib-refractory disease. Investigational new drugs, 2012, Volume: 30, Issue:6 Topics: Adult; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carcinoma, Hepatocellular; Drug Resistance, Neoplasm; Erlotinib Hydrochloride; Female; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Male; Middle Aged; Niacinamide; Phenylurea Compounds; Quinazolines; Sorafenib	2012
Bevacizumab and erlotinib in previously untreated inoperable and metastatic hepatocellular carcinoma. American journal of clinical oncology, 2013, Volume: 36, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carcinoma, Hepatocellular; Erlotinib Hydrochloride; Female; Follow-Up Studies; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Quinazolines; Salvage Therapy; Survival Rate; Treatment Outcome	2013
Efficacy, safety, pharmacokinetics, and biomarkers of cediranib monotherapy in advanced hepatocellular carcinoma: a phase II study. Clinical cancer research : an official journal of the American Association for Cancer Research, 2013, Mar-15, Volume: 19, Issue:6 Topics: Aged; Carcinoma, Hepatocellular; Disease-Free Survival; Drug-Related Side Effects and Adverse Reactions; Female; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Proteins; Neoplasm Staging; Protein Kinase Inhibitors; Quinazolines; Vascular Endothelial Growth Factor Receptor-1	2013
Elderly patients with fluoropyrimidine and thymidylate synthase inhibitor-resistant advanced colorectal cancer derive similar benefit without excessive toxicity when treated with irinotecan monotherapy. British journal of cancer, 2004, Oct-18, Volume: 91, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Peritoneal Neoplasms; Prospective Studies; Quinazolines; Salvage Therapy; Survival Rate; Thiophenes; Thymidylate Synthase; Treatment Outcome	2004
Phase I study of Tomudex and Doxorubicin in patients with locally advanced, inoperable or metastatic cancer (IND.98). Investigational new drugs, 2005, Volume: 23, Issue:1 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Doxorubicin; Female; Head and Neck Neoplasms; Humans; Liver Neoplasms; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Quinazolines; Salvage Therapy; Stomach Neoplasms; Thiophenes	2005
Epirubicin, cisplatin, and raltitrexed in patients with advanced gastric and hepatobiliary carcinoma: a phase II study. American journal of clinical oncology, 2004, Volume: 27, Issue:5 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Cisplatin; Epirubicin; Female; Humans; Liver Neoplasms; Male; Middle Aged; Quinazolines; Stomach Neoplasms; Survival Analysis; Thiophenes	2004
Phase I/II trial of gefitinib and oxaliplatin in patients with advanced colorectal cancer. American journal of clinical oncology, 2005, Volume: 28, Issue:4 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Disease-Free Survival; Drug Eruptions; Female; Gefitinib; Humans; Liver Neoplasms; Male; Middle Aged; Nausea; Organoplatinum Compounds; Oxaliplatin; Quinazolines; Survival Rate; Vomiting	2005
[Efficacy of gefitinib on Chinese patients with locally advanced or metastatic non-small cell lung cancer: a clinical trial]. Ai zheng = Aizheng = Chinese journal of cancer, 2005, Volume: 24, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; ErbB Receptors; Exanthema; Female; Gefitinib; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Pruritus; Quinazolines; Survival Rate	2005
Phase II study of Erlotinib (OSI-774) in patients with advanced hepatocellular cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Sep-20, Volume: 23, Issue:27 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Erlotinib Hydrochloride; Female; Follow-Up Studies; Humans; Liver Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Probability; Protein Kinase Inhibitors; Quinazolines; Survival Analysis; Treatment Outcome	2005
Phase II trial of nolatrexed dihydrochloride [Thymitaq, AG 337] in patients with advanced hepatocellular carcinoma. Investigational new drugs, 2007, Volume: 25, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Drug Administration Schedule; Exanthema; Female; Humans; Infusions, Intravenous; Liver Neoplasms; Male; Metabolic Clearance Rate; Middle Aged; Nausea; Quinazolines; Stomatitis; Survival Analysis; Time Factors; Treatment Outcome	2007
The use of perfusion CT for the evaluation of therapy combining AZD2171 with gefitinib in cancer patients. European radiology, 2007, Volume: 17, Issue:7 Topics: Administration, Oral; Adult; Aged; Angiography; Antineoplastic Combined Chemotherapy Protocols; Contrast Media; Disease Progression; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Gefitinib; Humans; Image Processing, Computer-Assisted; Injections, Intravenous; Liver Neoplasms; Male; Mediastinal Neoplasms; Middle Aged; Pancreatic Neoplasms; Pelvic Neoplasms; Pleural Neoplasms; Prognosis; Quinazolines; Tomography, Spiral Computed	2007
Population pharmacokinetics of a HER2 tyrosine kinase inhibitor CP-724,714 in patients with advanced malignant HER2 positive solid tumors. Cancer chemotherapy and pharmacology, 2007, Volume: 60, Issue:6 Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Body Weight; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Female; Humans; Liver Neoplasms; Middle Aged; Models, Biological; Multicenter Studies as Topic; Neoplasms; Nonlinear Dynamics; Quinazolines; Receptor, ErbB-2; Tissue Distribution	2007
Phase 2 study of erlotinib in patients with unresectable hepatocellular carcinoma. Cancer, 2007, Sep-01, Volume: 110, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Diarrhea; Drug Administration Schedule; ErbB Receptors; Erlotinib Hydrochloride; Exanthema; Fatigue; Female; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Liver Neoplasms; Male; Middle Aged; Protein Kinase Inhibitors; Quinazolines; Treatment Outcome	2007
Phase III randomized controlled trial comparing the survival of patients with unresectable hepatocellular carcinoma treated with nolatrexed or doxorubicin. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Jul-20, Volume: 25, Issue:21 Topics: Adult; Aged; Carcinoma, Hepatocellular; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Liver Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Palliative Care; Quality of Life; Quinazolines; Risk Assessment; Survival Analysis; Terminally Ill	2007
A phase II and pharmacokinetic study of SB-715992, in patients with metastatic hepatocellular carcinoma: a study of the National Cancer Institute of Canada Clinical Trials Group (NCIC CTG IND.168). Investigational new drugs, 2008, Volume: 26, Issue:3 Topics: Adult; Aged; Antineoplastic Agents; Benzamides; Carcinoma, Hepatocellular; Disease Progression; Female; Gene Expression; Humans; Infusions, Intravenous; Kinesins; Liver Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Quinazolines; Treatment Outcome	2008
A phase II study of raltitrexed ('Tomudex') in patients with hepatocellular carcinoma. Annals of oncology : official journal of the European Society for Medical Oncology, 1997, Volume: 8, Issue:5 Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Female; Folic Acid Antagonists; Humans; Liver Neoplasms; Male; Middle Aged; Quinazolines; Thiophenes	1997
A Phase II trial of nolatrexed dihydrochloride in patients with advanced hepatocellular carcinoma. Cancer, 1999, Aug-01, Volume: 86, Issue:3 Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Female; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Quinazolines; Survival Analysis; Thymidylate Synthase	1999
A multi-centre randomized phase II study of nolatrexed versus doxorubicin in treatment of Chinese patients with advanced hepatocellular carcinoma. Cancer chemotherapy and pharmacology, 1999, Volume: 44, Issue:4 Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma, Hepatocellular; Doxorubicin; Female; Humans; Infusions, Intravenous; Liver Neoplasms; Male; Middle Aged; Quinazolines; Survival Analysis	1999
Raltitrexed (Tomudex) administration in patients with relapsed metastatic colorectal cancer after weekly irinotecan/5-Fluorouracil/Leucovorin chemotherapy. BMC cancer, 2002, Volume: 2 Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Peritoneal Neoplasms; Quinazolines; Salvage Therapy; Secondary Prevention; Thiophenes; Treatment Outcome	2002
Trimetrexate in untreated and previously treated patients with metastatic breast cancer: a Cancer and Leukemia Group B study. Medical and pediatric oncology, 1991, Volume: 19, Issue:4 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Hematologic Diseases; Humans; Liver Neoplasms; Middle Aged; Quinazolines; Trimetrexate	1991

Other Studies

194 other study(ies) available for quinazolines and Cancer of Liver

Article	Year
QNZ alleviated hepatocellular carcinoma by targeting inflammatory pathways in a rat model. Cytokine, 2021, Volume: 148 Topics: alpha-Fetoproteins; Animals; beta Catenin; Carcinoma, Hepatocellular; Disease Models, Animal; Glycogen Synthase Kinase 3; Hepatocytes; Inflammation; Liver; Liver Neoplasms; MAP Kinase Kinase Kinase 5; NF-kappa B; Organ Specificity; Phenyl Ethers; Quinazolines; Rats; Rats, Sprague-Dawley; Survival Analysis; TNF Receptor-Associated Factor 2; Tumor Necrosis Factor-alpha	2021
A Critical YAP in Malignancy of HCC Is Regulated by Evodiamine. International journal of molecular sciences, 2022, Feb-06, Volume: 23, Issue:3 Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Mitochondria; Quinazolines; Up-Regulation; YAP-Signaling Proteins	2022
Design, synthesis, and biological evaluation of quinazoline derivatives with covalent reversible warheads as potential FGFR4 inhibitors. Bioorganic chemistry, 2022, Volume: 121 Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Humans; Liver Neoplasms; Quinazolines; Receptor, Fibroblast Growth Factor, Type 4	2022
Phase 0 Study of Vandetanib-Eluting Radiopaque Embolics as a Preoperative Embolization Treatment in Patients with Resectable Liver Malignancies. Journal of vascular and interventional radiology : JVIR, 2022, Volume: 33, Issue:9 Topics: Adolescent; Adult; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Humans; Liver Neoplasms; Piperidines; Protein Kinase Inhibitors; Quinazolines; Treatment Outcome	2022
Preliminary outcomes of raltitrexed eluting bead-transarterial chemoembolization using Callispheres® beads for gastrointestinal adenocarcinoma liver metastasis. World journal of surgical oncology, 2022, Jul-12, Volume: 20, Issue:1 Topics: Aged; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Female; Gastrointestinal Neoplasms; Humans; Liver Neoplasms; Male; Microspheres; Middle Aged; Quinazolines; Retrospective Studies; Thiophenes; Treatment Outcome	2022
Clinical Outcomes of Drug-Eluting Bead Transarterial Chemoembolization Loaded with Raltitrexed for the Treatment of Unresectable or Recurrent Hepatocellular Carcinoma. Canadian journal of gastroenterology & hepatology, 2022, Volume: 2022 Topics: Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Doxorubicin; Humans; Liver Neoplasms; Quinazolines; Retrospective Studies; Thiophenes; Treatment Outcome	2022
G9a and histone deacetylases are crucial for Snail2-mediated E-cadherin repression and metastasis in hepatocellular carcinoma. Cancer science, 2019, Volume: 110, Issue:11 Topics: Acetylation; Animals; Azepines; Cadherins; Carcinoma, Hepatocellular; Cell Movement; Disease Progression; Down-Regulation; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Female; Histocompatibility Antigens; Histone Deacetylase Inhibitors; Histone Deacetylases; Histone-Lysine N-Methyltransferase; Humans; Hydroxamic Acids; Liver; Liver Neoplasms; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Quinazolines; Snail Family Transcription Factors; Transcription, Genetic; Transforming Growth Factor beta	2019
Acquired On-Target Clinical Resistance Validates FGFR4 as a Driver of Hepatocellular Carcinoma. Cancer discovery, 2019, Volume: 9, Issue:12 Topics: Aged, 80 and over; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Fibroblast Growth Factors; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Male; Mice; Middle Aged; Models, Molecular; Mutation; Neoplasm Transplantation; Protein Domains; Pyrans; Quinazolines; Receptor, Fibroblast Growth Factor, Type 4	2019
Evolution of Transarterial Chemoembolization for the Treatment of Liver Cancer. Radiology, 2019, Volume: 293, Issue:3 Topics: Animals; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Liver Neoplasms; Piperidines; Quinazolines; Rabbits	2019
Nanodiamond-Mediated Delivery of a G9a Inhibitor for Hepatocellular Carcinoma Therapy. ACS applied materials & interfaces, 2019, Dec-11, Volume: 11, Issue:49 Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; DNA Methylation; Drug Delivery Systems; Gene Expression Regulation, Neoplastic; Histocompatibility Antigens; Histone Code; Histone-Lysine N-Methyltransferase; Humans; Liver Neoplasms; Mice; Nanodiamonds; Quinazolines	2019
Deubiquitinating enzyme USP10 promotes hepatocellular carcinoma metastasis through deubiquitinating and stabilizing Smad4 protein. Molecular oncology, 2020, Volume: 14, Issue:1 Topics: Animals; Benzylamines; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Protein Binding; Protein Stability; Quinazolines; RNA, Small Interfering; Smad4 Protein; Transforming Growth Factor beta; Ubiquitin Thiolesterase; Ubiquitination; Xenograft Model Antitumor Assays	2020
Oxaliplatin resistance is enhanced by saracatinib via upregulation Wnt-ABCG1 signaling in hepatocellular carcinoma. BMC cancer, 2020, Jan-13, Volume: 20, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 1; Benzodioxoles; Carcinoma, Hepatocellular; Cell Line, Tumor; Computational Biology; Disease Models, Animal; Drug Antagonism; Drug Resistance, Neoplasm; Gene Expression Profiling; Gene Expression Regulation; Humans; Liver Neoplasms; Mice; Oxaliplatin; Quinazolines; Signal Transduction; Wnt Proteins; Xenograft Model Antitumor Assays	2020
Knockdown of otubain 2 inhibits liver cancer cell growth by suppressing NF-κB signaling. The Kaohsiung journal of medical sciences, 2020, Volume: 36, Issue:6 Topics: Carcinogenesis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; Genes, Reporter; Hepatoblastoma; Humans; Liver Neoplasms; Luciferases; Phenyl Ethers; Phenylenediamines; Phosphorylation; Quinazolines; RNA, Small Interfering; Signal Transduction; Survival Analysis; Thiolester Hydrolases; Transcription Factor RelA	2020
Evodiamine inhibits proliferation and promotes apoptosis of hepatocellular carcinoma cells via the Hippo-Yes-Associated Protein signaling pathway. Life sciences, 2020, Jun-15, Volume: 251 Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Female; Hep G2 Cells; Hippo Signaling Pathway; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Protein Serine-Threonine Kinases; Quinazolines; Signal Transduction; Transcription Factors; Xenograft Model Antitumor Assays; YAP-Signaling Proteins	2020
A Case-Control Study on the Correlation Between Thymidylate Synthase Gene Polymorphisms and Raltitrexed Treatment Combined with Transcatheter Arterial Chemoembolization in Hepatocellular Carcinoma Treatment. Genetic testing and molecular biomarkers, 2020, Volume: 24, Issue:3 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Pharmacological; Carcinoma, Hepatocellular; Case-Control Studies; Chemoembolization, Therapeutic; Combined Modality Therapy; Female; Humans; Liver Neoplasms; Male; Middle Aged; Polymorphism, Single Nucleotide; Prognosis; Quinazolines; Survival Rate; Thiophenes; Thymidylate Synthase; Treatment Outcome	2020
Fibroblast Growth Factor 9 is expressed by activated hepatic stellate cells and promotes progression of hepatocellular carcinoma. Scientific reports, 2020, 03-11, Volume: 10, Issue:1 Topics: Acrylamides; Apoptosis; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Movement; Cell Proliferation; Fibroblast Growth Factor 9; Gene Expression Regulation, Neoplastic; Hepatic Stellate Cells; Humans; Liver Neoplasms; Prognosis; Quinazolines; Receptor, Fibroblast Growth Factor, Type 4; Survival Rate; Tumor Cells, Cultured	2020
CCL22 signaling contributes to sorafenib resistance in hepatitis B virus-associated hepatocellular carcinoma. Pharmacological research, 2020, Volume: 157 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chemokine CCL22; Drug Resistance, Neoplasm; Hep G2 Cells; Hepatitis B; Humans; Liver Neoplasms; Lymphocytes, Tumor-Infiltrating; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Protein Kinase Inhibitors; Quinazolines; Receptors, CCR4; Signal Transduction; Sorafenib; T-Lymphocytes; Tumor Burden	2020
Euchromatin histone methyltransferase II (EHMT2) regulates the expression of ras-related GTP binding C (RRAGC) protein. BMB reports, 2020, Volume: 53, Issue:11 Topics: Apoptosis; Azepines; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Chromatin Immunoprecipitation; Euchromatin; Gene Expression; Gene Expression Regulation; Histocompatibility Antigens; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Liver Neoplasms; Monomeric GTP-Binding Proteins; Proteomics; Quinazolines; Reactive Oxygen Species; Stress, Physiological; Transcriptome	2020
The quinazoline derivative, 04NB-03, induces cell cycle arrest and apoptosis in hepatocellular carcinoma cells in a reactive oxygen species-dependent manner. Chemico-biological interactions, 2021, Apr-01, Volume: 338 Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Female; G2 Phase Cell Cycle Checkpoints; Humans; Inhibitory Concentration 50; Liver Neoplasms; M Phase Cell Cycle Checkpoints; Mice, Inbred BALB C; Mice, Nude; Quinazolines; Reactive Oxygen Species	2021
Vandetanib-eluting radiopaque beads for chemoembolization: physicochemical evaluation and biological activity of vandetanib in hypoxia. Anti-cancer drugs, 2021, 10-01, Volume: 32, Issue:9 Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Chemoembolization, Therapeutic; Drug Liberation; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia; Liver Neoplasms; MAP Kinase Signaling System; Neovascularization, Pathologic; Piperidines; Quinazolines; Vascular Endothelial Growth Factors	2021
HER3 PET Imaging Identifies Dynamic Changes in HER3 in Response to HER2 Inhibition with Lapatinib. Molecular imaging and biology, 2021, Volume: 23, Issue:6 Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Humans; Lapatinib; Liver Neoplasms; Mice; Positron-Emission Tomography; Quinazolines; Receptor, ErbB-2; Receptor, ErbB-3; Tissue Distribution	2021
Design, synthesis and bioactivity study of evodiamine derivatives as multifunctional agents for the treatment of hepatocellular carcinoma. Bioorganic chemistry, 2021, Volume: 114 Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Mice; Mice, Nude; Molecular Structure; Quinazolines; Structure-Activity Relationship; Tumor Cells, Cultured	2021
Histone lysine methyltransferase G9a is a novel epigenetic target for the treatment of hepatocellular carcinoma. Oncotarget, 2017, Mar-28, Volume: 8, Issue:13 Topics: Adult; Aged; Aged, 80 and over; Animals; Azepines; Blotting, Western; Carcinoma, Hepatocellular; Chromatin Immunoprecipitation; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Humans; Immunohistochemistry; Liver Neoplasms; Male; Mice; Mice, Inbred NOD; Mice, SCID; Middle Aged; Quinazolines; Real-Time Polymerase Chain Reaction; Xenograft Model Antitumor Assays	2017
Real-World Data on Prognostic Factors for Overall Survival in EGFR Mutation-Positive Advanced Non-Small Cell Lung Cancer Patients Treated with First-Line Gefitinib. The oncologist, 2017, Volume: 22, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free Survival; ErbB Receptors; Female; Gain of Function Mutation; Gefitinib; Hepatitis C, Chronic; Humans; Liver Neoplasms; Lung; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Quinazolines; Retrospective Studies; Smoking; Taiwan	2017
Drug design, development and therapy, 2017, Volume: 11 Topics: Antineoplastic Agents; Benzenesulfonates; Carbon-13 Magnetic Resonance Spectroscopy; Carcinoma, Hepatocellular; Cell Proliferation; Chromatography, Liquid; Dose-Response Relationship, Drug; Drug Design; Hep G2 Cells; Humans; Liver Neoplasms; Mass Spectrometry; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Proton Magnetic Resonance Spectroscopy; Pyrimidines; Quinazolines; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship	2017
Evodiamine Exerts an Anti-Hepatocellular Carcinoma Activity through a WWOX-Dependent Pathway. Molecules (Basel, Switzerland), 2017, Jul-14, Volume: 22, Issue:7 Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; beta Catenin; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Evodia; Gene Knockdown Techniques; Humans; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Plant Extracts; Quinazolines; WW Domain-Containing Oxidoreductase	2017
HZ-6d targeted HERC5 to regulate p53 ISGylation in human hepatocellular carcinoma. Toxicology and applied pharmacology, 2017, 11-01, Volume: 334 Topics: Antineoplastic Agents; Benzofurans; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Delivery Systems; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Quinazolines; Tumor Suppressor Protein p53	2017
Implications of FGF19 on sorafenib-mediated nitric oxide production in hepatocellular carcinoma cells - a short report. Cellular oncology (Dordrecht), 2018, Volume: 41, Issue:1 Topics: Acrylamides; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Fibroblast Growth Factors; Hep G2 Cells; Humans; Liver Neoplasms; Niacinamide; Nitric Oxide; Phenylurea Compounds; Protein Kinase Inhibitors; Quinazolines; Receptor, Fibroblast Growth Factor, Type 4; Sorafenib	2018
Inhibition of CUG-binding protein 1 and activation of caspases are critically involved in piperazine derivative BK10007S induced apoptosis in hepatocellular carcinoma cells. PloS one, 2017, Volume: 12, Issue:10 Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Caspases; CELF1 Protein; Cell Proliferation; Enzyme Activation; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Piperazines; Quinazolines	2017
Sequential occurrence of small cell and non-small lung cancer in a male patient: Is it a transformation? Cancer biology & therapy, 2017, Dec-02, Volume: 18, Issue:12 Topics: Adenocarcinoma; Adenocarcinoma of Lung; Afatinib; Aged; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Humans; Liver Neoplasms; Lung Neoplasms; Male; Neoplasm Metastasis; Positron Emission Tomography Computed Tomography; Protein Kinase Inhibitors; Quinazolines; Small Cell Lung Carcinoma	2017
Evodiamine induces apoptosis and promotes hepatocellular carcinoma cell death induced by vorinostat via downregulating HIF-1α under hypoxia. Biochemical and biophysical research communications, 2018, 04-06, Volume: 498, Issue:3 Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Drug Synergism; Humans; Hydroxamic Acids; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms; Quinazolines; Vorinostat	2018
MEF2C promotes gefitinib resistance in hepatic cancer cells through regulating MIG6 transcription. Tumori, 2018, Volume: 104, Issue:3 Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; MEF2 Transcription Factors; Mice; Mice, Nude; Promoter Regions, Genetic; Protein Kinase Inhibitors; Quinazolines; Transcription, Genetic; Tumor Suppressor Proteins; Up-Regulation	2018
Antagonizing SET Augments the Effects of Radiation Therapy in Hepatocellular Carcinoma through Reactivation of PP2A-Mediated Akt Downregulation. The Journal of pharmacology and experimental therapeutics, 2018, Volume: 366, Issue:3 Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; DNA-Binding Proteins; Down-Regulation; Enzyme Activation; Histone Chaperones; Humans; Liver Neoplasms; Male; Mice; Protein Phosphatase 2; Proto-Oncogene Proteins c-akt; Quinazolines; Transcription Factors; Xenograft Model Antitumor Assays	2018
Transarterial embolization and low-dose continuous hepatic arterial infusion chemotherapy with oxaliplatin and raltitrexed for hepatocellular carcinoma with major portal vein tumor thrombus. World journal of gastroenterology, 2018, Jun-21, Volume: 24, Issue:23 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Catheters; Chemoembolization, Therapeutic; Female; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Portal Vein; Quinazolines; Retrospective Studies; Survival Rate; Thiophenes; Thrombosis; Treatment Outcome	2018
Efficacy and safety of raltitrexed-based transarterial chemoembolization for colorectal cancer liver metastases. Anti-cancer drugs, 2018, Volume: 29, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoembolization, Therapeutic; China; Colorectal Neoplasms; Disease Progression; Ethiodized Oil; Female; Follow-Up Studies; Humans; Liver Neoplasms; Male; Middle Aged; Oxaliplatin; Prospective Studies; Quinazolines; Survival; Thiophenes	2018
Transarterial chemoembolization with raltitrexed-based or floxuridine-based chemotherapy for unresectable colorectal cancer liver metastasis. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2019, Volume: 21, Issue:4 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoembolization, Therapeutic; Colorectal Neoplasms; Female; Floxuridine; Humans; Liver Neoplasms; Male; Middle Aged; Prognosis; Quinazolines; Retrospective Studies; Survival Analysis; Thiophenes; Treatment Outcome	2019
Evodiamine Induces Apoptosis in SMMC-7721 and HepG2 Cells by Suppressing NOD1 Signal Pathway. International journal of molecular sciences, 2018, Oct-31, Volume: 19, Issue:11 Topics: Animals; Carcinoma, Hepatocellular; Hep G2 Cells; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Nod1 Signaling Adaptor Protein; Quinazolines; Signal Transduction; Xenograft Model Antitumor Assays	2018
AZD3759 induces apoptosis in hepatoma cells by activating a p53-SMAD4 positive feedback loop. Biochemical and biophysical research communications, 2019, 02-05, Volume: 509, Issue:2 Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Piperazines; Quinazolines; Signal Transduction; Smad4 Protein; Tumor Suppressor Protein p53	2019
A concise synthesis and biological study of evodiamine and its analogues. Chemical communications (Cambridge, England), 2019, Mar-07, Volume: 55, Issue:21 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Chemistry Techniques, Synthetic; Evodia; Humans; Liver Neoplasms; Quinazolines	2019
Predicting pharmacokinetic behaviour of drug release from drug-eluting embolization beads using in vitro elution methods. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2019, Aug-01, Volume: 136 Topics: Animals; Chemoembolization, Therapeutic; Doxorubicin; Drug Delivery Systems; Drug Liberation; In Vitro Techniques; Irinotecan; Liver; Liver Neoplasms; Piperidines; Quinazolines; Swine	2019
Down-regulation of Survivin by BIX-01294 Pretreatment Overcomes Resistance of Hepatocellular Carcinoma Cells to TRAIL. Anticancer research, 2019, Volume: 39, Issue:7 Topics: Azepines; Carcinoma, Hepatocellular; Cell Line, Tumor; Down-Regulation; Drug Resistance, Neoplasm; Humans; Liver Neoplasms; Quinazolines; Survivin; TNF-Related Apoptosis-Inducing Ligand	2019
Growth inhibitor of human hepatic carcinoma HepG2 cells by evodiamine is associated with downregulation of PRAME. Naunyn-Schmiedeberg's archives of pharmacology, 2019, Volume: 392, Issue:12 Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Survival; Down-Regulation; Hep G2 Cells; Humans; Liver Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; Quinazolines; RNA, Messenger	2019
Epidermal growth factor receptor signaling impairs the antiviral activity of interferon-alpha. Hepatology (Baltimore, Md.), 2013, Volume: 58, Issue:4 Topics: Antiviral Agents; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Drug Synergism; Drug Therapy, Combination; ErbB Receptors; Erlotinib Hydrochloride; Hepacivirus; Hepatitis C; Hepatocytes; Humans; Interferon-alpha; Liver Neoplasms; Quinazolines; Receptor Protein-Tyrosine Kinases; Signal Transduction; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Treatment Outcome	2013
Cutaneous leukocytoclastic vasculitis due to erlotinib: just an adverse event or also a putative marker of drug efficacy? Cutaneous and ocular toxicology, 2013, Volume: 32, Issue:4 Topics: Aged; Antineoplastic Agents; Carcinoma, Hepatocellular; Erlotinib Hydrochloride; Humans; Liver Neoplasms; Male; Protein Kinase Inhibitors; Quinazolines; Treatment Outcome; Vasculitis, Leukocytoclastic, Cutaneous	2013
Synthesis, tautomeric structures, and antitumor activity of new perimidines. Archiv der Pharmazie, 2013, Volume: 346, Issue:5 Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma, Hepatocellular; Female; Hep G2 Cells; Humans; Liver Neoplasms; MCF-7 Cells; Quinazolines; Spectrum Analysis	2013
The addition of erlotinib to gemcitabine and cisplatin does not appear to improve median survival in metastatic pancreatic cancer. Investigational new drugs, 2013, Volume: 31, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Deoxycytidine; Erlotinib Hydrochloride; Female; Gemcitabine; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pancreatic Neoplasms; Peritoneal Neoplasms; Protein Kinase Inhibitors; Quinazolines	2013
Hepatic myofibroblasts promote the progression of human cholangiocarcinoma through activation of epidermal growth factor receptor. Hepatology (Baltimore, Md.), 2013, Volume: 58, Issue:6 Topics: Animals; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cell Line, Tumor; Cholangiocarcinoma; Disease Progression; ErbB Receptors; Gefitinib; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Liver Neoplasms; Mice; Myofibroblasts; Quinazolines; Signal Transduction; Stromal Cells	2013
Prognostic factors of brain metastases from breast cancer: impact of targeted therapies. Breast (Edinburgh, Scotland), 2013, Volume: 22, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Carcinoma, Ductal, Breast; Disease-Free Survival; Female; Humans; Intracranial Hypertension; Kaplan-Meier Estimate; Lapatinib; Liver Neoplasms; Middle Aged; Molecular Targeted Therapy; Quinazolines; Radiosurgery; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies; Survival Rate; Trastuzumab; Young Adult	2013
[A case of pancreatic body cancer with multiple liver metastases experiencing long-term response by gemcitabine plus erlotinib therapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:6 Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Erlotinib Hydrochloride; Fatal Outcome; Gemcitabine; Humans; Liver Neoplasms; Male; Middle Aged; Pancreatic Neoplasms; Quinazolines; Time Factors	2013
Erlotinib response in an NSCLC patient with a novel compound G719D+L861R mutation in EGFR. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2013, Volume: 8, Issue:9 Topics: Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Erlotinib Hydrochloride; Female; Humans; Liver Neoplasms; Lung Neoplasms; Middle Aged; Mutation; Prognosis; Protein Kinase Inhibitors; Quinazolines	2013
BCRP/ABCG2 inhibition sensitizes hepatocellular carcinoma cells to sorafenib. PloS one, 2013, Volume: 8, Issue:12 Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport, Active; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Gefitinib; Hep G2 Cells; Humans; Liver Neoplasms; MAP Kinase Signaling System; Neoplasm Proteins; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Quinazolines; RNA, Small Interfering; Sorafenib	2013
Tyrosine kinase inhibitor treatments in patients with metastatic thyroid carcinomas: a retrospective study of the TUTHYREF network. European journal of endocrinology, 2014, Volume: 170, Issue:4 Topics: Adenocarcinoma; Adenocarcinoma, Follicular; Adenoma, Oxyphilic; Adult; Aged; Antineoplastic Agents; Bone Neoplasms; Carcinoma; Carcinoma, Neuroendocrine; Carcinoma, Papillary; Disease-Free Survival; Female; Humans; Indoles; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Niacinamide; Phenylurea Compounds; Piperidines; Pleural Neoplasms; Protein-Tyrosine Kinases; Pyrroles; Quinazolines; Retrospective Studies; Sorafenib; Sunitinib; Thyroid Cancer, Papillary; Thyroid Neoplasms; Treatment Outcome	2014
Upregulation of HIF-2α induced by sorafenib contributes to the resistance by activating the TGF-α/EGFR pathway in hepatocellular carcinoma cells. Cellular signalling, 2014, Volume: 26, Issue:5 Topics: Animals; Antineoplastic Agents; Basic Helix-Loop-Helix Transcription Factors; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Resistance, Neoplasm; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Gefitinib; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Niacinamide; Phenylurea Compounds; Quinazolines; Signal Transduction; Sorafenib; Transforming Growth Factor alpha; Up-Regulation	2014
Caffeine and the analog CGS 15943 inhibit cancer cell growth by targeting the phosphoinositide 3-kinase/Akt pathway. Cancer biology & therapy, 2014, Volume: 15, Issue:5 Topics: Antineoplastic Agents; Apoptosis; Caffeine; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Humans; Liver Neoplasms; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Purinergic P1 Receptor Agonists; Quinazolines; Signal Transduction; Triazoles	2014
In-depth analysis shows synergy between erlotinib and miR-34a. PloS one, 2014, Volume: 9, Issue:2 Topics: Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Erlotinib Hydrochloride; Humans; Liver Neoplasms; Lung Neoplasms; MicroRNAs; Quinazolines	2014
Epidermal growth factor receptor inhibition attenuates liver fibrosis and development of hepatocellular carcinoma. Hepatology (Baltimore, Md.), 2014, Volume: 59, Issue:4 Topics: Animals; Bile Ducts; Carbon Tetrachloride; Carcinoma, Hepatocellular; Cell Proliferation; Cells, Cultured; Diethylnitrosamine; Disease Models, Animal; Disease Progression; ErbB Receptors; Erlotinib Hydrochloride; Hepatic Stellate Cells; Hepatocytes; Humans; Ligation; Liver Cirrhosis; Liver Neoplasms; Male; Mice; Mice, Inbred Strains; Phosphorylation; Prognosis; Quinazolines; Rats; Rats, Wistar; Transcriptome	2014
Erlotinib might be a double-edged sword in HCC. Hepatology (Baltimore, Md.), 2015, Volume: 61, Issue:2 Topics: Animals; Carcinoma, Hepatocellular; Disease Progression; ErbB Receptors; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Quinazolines	2015
Reply: To PMID 24677197. Hepatology (Baltimore, Md.), 2015, Volume: 61, Issue:2 Topics: Animals; Carcinoma, Hepatocellular; Disease Progression; ErbB Receptors; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Quinazolines	2015
Entrapment of an EGFR inhibitor into nanostructured lipid carriers (NLC) improves its antitumor activity against human hepatocarcinoma cells. Journal of nanobiotechnology, 2014, May-12, Volume: 12 Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Carriers; ErbB Receptors; Humans; Lipids; Liver; Liver Neoplasms; Nanostructures; Quinazolines; Tyrphostins	2014
Epidermal growth factor-like domain-containing protein 7 (EGFL7) enhances EGF receptor-AKT signaling, epithelial-mesenchymal transition, and metastasis of gastric cancer cells. PloS one, 2014, Volume: 9, Issue:6 Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Animals; Calcium-Binding Proteins; Cell Line, Tumor; Cell Movement; EGF Family of Proteins; Endothelial Growth Factors; Epithelial-Mesenchymal Transition; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Male; Mice; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Neoplasm Transplantation; Proto-Oncogene Proteins c-akt; Quinazolines; RNA, Small Interfering; Signal Transduction; Snail Family Transcription Factors; Stomach Neoplasms; Transcription Factors; Tyrphostins; Vimentin	2014
Lapatinib induces autophagic cell death and inhibits growth of human hepatocellular carcinoma. Oncotarget, 2014, Jul-15, Volume: 5, Issue:13 Topics: Animals; Apoptosis Regulatory Proteins; Autophagy; Autophagy-Related Protein 5; Autophagy-Related Protein 7; Beclin-1; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Immunoblotting; Lapatinib; Liver Neoplasms; Membrane Proteins; Mice, Inbred BALB C; Mice, Nude; Microscopy, Electron, Transmission; Microtubule-Associated Proteins; Mitochondria; Protein Kinase Inhibitors; Quinazolines; RNA Interference; Tumor Burden; Ubiquitin-Activating Enzymes; Xenograft Model Antitumor Assays	2014
An improved isoprenylcysteine carboxylmethyltransferase inhibitor induces cancer cell death and attenuates tumor growth in vivo. Cancer biology & therapy, 2014, Volume: 15, Issue:9 Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; ErbB Receptors; Female; Gefitinib; Heterografts; Humans; Indoles; Lamin Type A; Liver Neoplasms; Methylation; Mice, SCID; Oncogene Protein p21(ras); Protein Methyltransferases; Protein Prenylation; Pyrimidines; Quinazolines	2014
Erlotinib derivative inhibits hepatocellular carcinoma by targeting CIP2A to reactivate protein phosphatase 2A. Cell death & disease, 2014, Jul-31, Volume: 5 Topics: Animals; Antineoplastic Agents; Apoptosis; Autoantigens; Carcinoma, Hepatocellular; Cell Line, Tumor; Erlotinib Hydrochloride; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Male; Membrane Proteins; Mice; Mice, Nude; Protein Phosphatase 2; Proto-Oncogene Proteins c-akt; Quinazolines; Xenograft Model Antitumor Assays	2014
[Inhibitory effect of norcantharidin combined with evodiamine on the growth of human hepatic carcinoma cell line HepG2 in vitro]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2014, Volume: 30, Issue:8 Topics: Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Flow Cytometry; G2 Phase Cell Cycle Checkpoints; Hep G2 Cells; Hepatoblastoma; Humans; Liver Neoplasms; Proto-Oncogene Proteins c-bcl-2; Quinazolines	2014
Effective treatment with icotinib in primary adenoid cystic carcinoma of the lung with liver metastasis. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2014, Volume: 9, Issue:9 Topics: Adult; Biopsy; Carcinoma, Adenoid Cystic; Crown Ethers; Follow-Up Studies; Humans; Liver Neoplasms; Lung Neoplasms; Male; Quinazolines; Tomography, X-Ray Computed	2014
Molecular-target-based anticancer photosensitizer: synthesis and in vitro photodynamic activity of erlotinib-zinc(II) phthalocyanine conjugates. ChemMedChem, 2015, Volume: 10, Issue:2 Topics: Antineoplastic Agents; Apoptosis; Cell Line; Drug Design; ErbB Receptors; Erlotinib Hydrochloride; Hep G2 Cells; Humans; Indoles; Isoindoles; Light; Liver Neoplasms; Microscopy, Confocal; Organometallic Compounds; Photochemotherapy; Photosensitizing Agents; Quinazolines; Structure-Activity Relationship; Zinc Compounds	2015
Reactive oxygen species-mediated activation of the Src-epidermal growth factor receptor-Akt signaling cascade prevents bortezomib-induced apoptosis in hepatocellular carcinoma cells. Molecular medicine reports, 2015, Volume: 11, Issue:1 Topics: Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Humans; Liver Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrazines; Quinazolines; Reactive Oxygen Species; Signal Transduction; src-Family Kinases	2015
Des-gamma-carboxy prothrombin (DCP) antagonizes the effects of gefitinib on human hepatocellular carcinoma cells. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2015, Volume: 35, Issue:1 Topics: Antineoplastic Agents; Apoptosis; Biomarkers; Carcinoma, Hepatocellular; Caspases; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Gefitinib; Hep G2 Cells; Hepatocyte Growth Factor; Humans; Liver Neoplasms; Protein Precursors; Prothrombin; Proto-Oncogene Proteins c-met; Quinazolines; Up-Regulation	2015
Disease progression pattern in metastatic breast cancer patients treated with anti-HER2 therapies. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2015, Volume: 17, Issue:7 Topics: Adult; Aged; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Central Nervous System Neoplasms; Disease Progression; Female; Humans; Lapatinib; Liver Neoplasms; Lung Neoplasms; Middle Aged; Prognosis; Proportional Hazards Models; Quinazolines; Receptor, ErbB-2; Retrospective Studies; Time Factors; Trastuzumab; Treatment Outcome	2015
Breast cancer brain metastases responding to lapatinib plus capecitabine as second-line primary systemic therapy. Anti-cancer drugs, 2015, Volume: 26, Issue:5 Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Capecitabine; Deoxycytidine; Female; Fluorouracil; Humans; Lapatinib; Liver Neoplasms; Middle Aged; Quinazolines; Receptor, ErbB-2; Trastuzumab	2015
Liver metastasis predicts poorer prognosis in stage IV lung adenocarcinoma patients receiving first-line gefitinib. Lung cancer (Amsterdam, Netherlands), 2015, Volume: 88, Issue:2 Topics: Adenocarcinoma; Adenocarcinoma of Lung; Aged; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; ErbB Receptors; Female; Gefitinib; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Mutation; Neoplasm Staging; Prognosis; Protein Kinase Inhibitors; Quinazolines; Retrospective Studies; Treatment Outcome	2015
Icotinib plus gemcitabine for metastatic pancreatic cancer: a case report. World journal of gastroenterology, 2015, Mar-21, Volume: 21, Issue:11 Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Crown Ethers; Deoxycytidine; Gemcitabine; Humans; Liver Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Molecular Targeted Therapy; Pancreatic Neoplasms; Positron-Emission Tomography; Protein Kinase Inhibitors; Quinazolines; Tomography, X-Ray Computed; Treatment Outcome; Tumor Burden	2015
Combined treatment with silibinin and either sorafenib or gefitinib enhances their growth-inhibiting effects in hepatocellular carcinoma cells. Clinical and molecular hepatology, 2015, Volume: 21, Issue:1 Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Survival; Down-Regulation; Drug Screening Assays, Antitumor; Drug Synergism; ErbB Receptors; Gefitinib; Humans; Liver Neoplasms; Niacinamide; Phenylurea Compounds; Proto-Oncogene Proteins c-akt; Quinazolines; Signal Transduction; Silybin; Silymarin; Sorafenib	2015
Modulation of Regorafenib effects on HCC cell lines by epidermal growth factor. Cancer chemotherapy and pharmacology, 2015, Volume: 75, Issue:6 Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Epidermal Growth Factor; Erlotinib Hydrochloride; Hep G2 Cells; Humans; Liver Neoplasms; MAP Kinase Signaling System; Niacinamide; Phenylurea Compounds; Phosphorylation; Pyridines; Quinazolines; Sorafenib	2015
Response to dual HER2 blockade in a patient with HER3-mutant metastatic breast cancer. Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:8 Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Lapatinib; Liver Neoplasms; Middle Aged; Mutation; Quinazolines; Receptor, ErbB-2; Receptor, ErbB-3; Trastuzumab	2015
The Histone Methyltransferase Inhibitor BIX01294 Inhibits HIF-1α Stability and Angiogenesis. Molecules and cells, 2015, Volume: 38, Issue:6 Topics: Animals; Azepines; Carcinoma, Hepatocellular; Chick Embryo; Enzyme Inhibitors; Hep G2 Cells; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms; Mice; Neovascularization, Pathologic; Quinazolines; Signal Transduction	2015
[A Case of Effective Whole-Brain Irradiation and Lapatinib/Capecitabine Combination Therapy for HER2-Positive Breast Cancer with Multiple Brain Metastases]. Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Capecitabine; Chemoradiotherapy; Deoxycytidine; Female; Fluorouracil; Humans; Lapatinib; Liver Neoplasms; Middle Aged; Quinazolines; Receptor, ErbB-2; Remission Induction	2015
EGFR mutation L747P led to gefitinib resistance and accelerated liver metastases in a Chinese patient with lung adenocarcinoma. International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:7 Topics: Adenocarcinoma; Adenocarcinoma of Lung; Aged; Antineoplastic Agents; Base Sequence; Biomarkers, Tumor; Biopsy; Chemotherapy, Adjuvant; China; Disease Progression; DNA Mutational Analysis; Drug Resistance, Neoplasm; ErbB Receptors; Exons; Gefitinib; Genetic Predisposition to Disease; Humans; Immunohistochemistry; Liver Neoplasms; Lung Neoplasms; Male; Molecular Sequence Data; Mutation; Phenotype; Protein Kinase Inhibitors; Quinazolines; Time Factors; Tomography, X-Ray Computed; Treatment Outcome	2015
A clinical case of invasive lobular breast carcinoma with ERBB2 and CDH1 mutations presenting a dramatic response to anti-HER2-directed therapy. Annals of oncology : official journal of the European Society for Medical Oncology, 2016, Volume: 27, Issue:1 Topics: Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cadherins; Capecitabine; Carcinoma, Lobular; Female; Humans; Lapatinib; Liver Neoplasms; Middle Aged; Molecular Targeted Therapy; Mutation, Missense; Quinazolines; Radiography; Receptor, ErbB-2; Treatment Outcome	2016
Multifocal clonal evolution characterized using circulating tumour DNA in a case of metastatic breast cancer. Nature communications, 2015, Nov-04, Volume: 6 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bayes Theorem; Brain Neoplasms; Breast Neoplasms; Carcinoma, Ductal, Breast; Case-Control Studies; Clonal Evolution; Deoxycytidine; DNA, Neoplasm; Female; Gemcitabine; Humans; Lapatinib; Liver Neoplasms; Lung Neoplasms; Mutation; Neoplasm Metastasis; Quinazolines; Receptor, ErbB-2; Receptors, Estrogen; Sequence Analysis, DNA; Spinal Neoplasms; Tamoxifen; Trastuzumab	2015
HBx sensitizes hepatocellular carcinoma cells to lapatinib by up-regulating ErbB3. Oncotarget, 2016, Jan-05, Volume: 7, Issue:1 Topics: Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Cell Survival; ErbB Receptors; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Hepatitis B virus; Humans; Lapatinib; Liver Neoplasms; NF-kappa B; Protein Kinase Inhibitors; Quinazolines; Receptor, ErbB-2; Receptor, ErbB-3; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Trans-Activators; Up-Regulation; Viral Regulatory and Accessory Proteins	2016
Gefitinib Synergizes with Irinotecan to Suppress Hepatocellular Carcinoma via Antagonizing Rad51-Mediated DNA-Repair. PloS one, 2016, Volume: 11, Issue:1 Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Camptothecin; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; DNA Repair; Drug Resistance, Neoplasm; Drug Synergism; Gefitinib; Hep G2 Cells; Humans; Irinotecan; Liver Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Quinazolines; Rad51 Recombinase; RNA, Small Interfering; Topoisomerase I Inhibitors	2016
Upregulation of the oncoprotein SET determines poor clinical outcomes in hepatocellular carcinoma and shows therapeutic potential. Oncogene, 2016, 09-15, Volume: 35, Issue:37 Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Histone Chaperones; Humans; Liver Neoplasms; Male; Mice; Niacinamide; Phenylurea Compounds; Prognosis; Quinazolines; Sorafenib; Transcription Factors; Xenograft Model Antitumor Assays	2016
Partial Remission of Hepatic Metastatic Lesion but Complicated with Secondary and Refractory Fever Lead by Nivolumab in a Patient with Lung Adenocarcinoma Presenting Gefitinib Acquired Resistance. Chinese medical journal, 2016, Apr-05, Volume: 129, Issue:7 Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antibodies, Monoclonal; Drug Resistance, Neoplasm; Female; Fever; Gefitinib; Humans; Liver Neoplasms; Lung Neoplasms; Middle Aged; Nivolumab; Quinazolines	2016
Raltitrexed Inhibits HepG2 Cell Proliferation via G0/G1 Cell Cycle Arrest. Oncology research, 2016, Volume: 23, Issue:5 Topics: Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Proliferation; Cyclin A; Cyclin-Dependent Kinase 2; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Genes, p16; Genes, p53; Hep G2 Cells; Humans; Liver Neoplasms; Quinazolines; Resting Phase, Cell Cycle; S Phase; Thiophenes	2016
Bi-weekly very-high-dose lapatinib: an easy-to-use active option in HER-2-positive breast cancer patients with meningeal carcinomatosis. Breast cancer research and treatment, 2016, Volume: 157, Issue:1 Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Diarrhea; Female; Humans; Lapatinib; Liver Neoplasms; Magnetic Resonance Imaging; Meningeal Carcinomatosis; Quinazolines; Receptor, ErbB-2; Trastuzumab; Treatment Outcome	2016
iRGD-Decorated Polymeric Nanoparticles for the Efficient Delivery of Vandetanib to Hepatocellular Carcinoma: Preparation and in Vitro and in Vivo Evaluation. ACS applied materials & interfaces, 2016, Aug-03, Volume: 8, Issue:30 Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Drug Delivery Systems; Liver Neoplasms; Mice; Nanoparticles; Piperidines; Polymers; Quinazolines	2016
Evodiamine exerts anti-tumor effects against hepatocellular carcinoma through inhibiting β-catenin-mediated angiogenesis. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:9 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; beta Catenin; Blotting, Western; Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; Cell Movement; Cell Survival; Evodia; Hep G2 Cells; Humans; Immunohistochemistry; Liver Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Phytotherapy; Plant Extracts; Quinazolines; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays	2016
Effect of saracatinib on pulmonary metastases from hepatocellular carcinoma. Oncology reports, 2016, Volume: 36, Issue:3 Topics: Animals; Benzodioxoles; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Humans; Liver Neoplasms; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Phosphorylation; Quinazolines; Signal Transduction; src-Family Kinases; Xenograft Model Antitumor Assays	2016
Heterogeneity of the resistance to gefitinib treatment in a non-small cell lung cancer patient with active epidermal growth factor receptor mutation. Thoracic cancer, 2017, Volume: 8, Issue:1 Topics: Adult; Carcinoma, Non-Small-Cell Lung; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Genetic Heterogeneity; Humans; Liver Neoplasms; Lung Neoplasms; Male; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Quinazolines; Treatment Outcome	2017
Regorafenib induces extrinsic and intrinsic apoptosis through inhibition of ERK/NF-κB activation in hepatocellular carcinoma cells. Oncology reports, 2017, Volume: 37, Issue:2 Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Humans; Liver Neoplasms; Membrane Potential, Mitochondrial; NF-kappa B; Phenyl Ethers; Phenylurea Compounds; Phosphorylation; Pyridines; Quinazolines; X-Linked Inhibitor of Apoptosis Protein	2017
Choline Kinase α Mediates Interactions Between the Epidermal Growth Factor Receptor and Mechanistic Target of Rapamycin Complex 2 in Hepatocellular Carcinoma Cells to Promote Drug Resistance and Xenograft Tumor Progression. Gastroenterology, 2017, Volume: 152, Issue:5 Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; Cell Movement; Choline Kinase; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; Hep G2 Cells; Humans; Immunoblotting; Immunohistochemistry; Liver Neoplasms; Mechanistic Target of Rapamycin Complex 2; Mice; Multiprotein Complexes; Neoplasm Invasiveness; Neoplasm Transplantation; Quinazolines; RNA, Messenger; TOR Serine-Threonine Kinases; Wound Healing; Xenograft Model Antitumor Assays	2017
Preparation and characterisation of vandetanib-eluting radiopaque beads for locoregional treatment of hepatic malignancies. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2017, Apr-01, Volume: 101 Topics: Carcinoma, Hepatocellular; Contrast Media; Drug Carriers; ErbB Receptors; Humans; Liver Neoplasms; Microspheres; Piperidines; Quinazolines; Vascular Endothelial Growth Factor A	2017
Anti-tumor effect of evodiamine by inducing Akt-mediated apoptosis in hepatocellular carcinoma. Biochemical and biophysical research communications, 2017, 03-25, Volume: 485, Issue:1 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Evodia; Hep G2 Cells; Humans; Liver; Liver Neoplasms; Proto-Oncogene Proteins c-akt; Quinazolines	2017
Heterogeneity in Immune Marker Expression after Acquisition of Resistance to EGFR Kinase Inhibitors: Analysis of a Case with Small Cell Lung Cancer Transformation. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2017, Volume: 12, Issue:6 Topics: Adenocarcinoma; Aged; Biomarkers; Cell Transformation, Neoplastic; Drug Resistance, Neoplasm; ErbB Receptors; Female; Gefitinib; Humans; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Mutation; Prognosis; Protein Kinase Inhibitors; Quinazolines; Small Cell Lung Carcinoma	2017
Enhancement of apoptosis of human hepatocellular carcinoma SMMC-7721 cells through synergy of berberine and evodiamine. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2008, Volume: 15, Issue:12 Topics: Apoptosis; Berberine; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Drug Synergism; Humans; Liver Neoplasms; Phytotherapy; Plant Extracts; Quinazolines; Tumor Necrosis Factor-alpha	2008
The inhibition of the epidermal growth factor (EGF) pathway enhances TGF-beta-induced apoptosis in rat hepatoma cells through inducing oxidative stress coincident with a change in the expression pattern of the NADPH oxidases (NOX) isoforms. Biochimica et biophysica acta, 2009, Volume: 1793, Issue:2 Topics: Animals; Antioxidants; Apoptosis; Carcinoma, Hepatocellular; Epidermal Growth Factor; ErbB Receptors; Gene Expression Regulation, Neoplastic; Isoenzymes; Liver Neoplasms; Mitochondria; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; Protein Kinase Inhibitors; Quinazolines; Rats; Reactive Oxygen Species; RNA, Small Interfering; Transforming Growth Factor beta; Tyrphostins	2009
Long-term treatment of advanced hepatocellular carcinoma with the tyrosine kinase inhibitor erlotinib (Tarceva)--a case report. Zeitschrift fur Gastroenterologie, 2009, Volume: 47, Issue:1 Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Drug Eruptions; Erlotinib Hydrochloride; Fatal Outcome; Follow-Up Studies; Humans; Liver Cirrhosis, Alcoholic; Liver Function Tests; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Palliative Care; Quinazolines; Ultrasonography	2009
EGFR-TKI and lung adenocarcinoma with CNS relapse: interest of molecular follow-up. The European respiratory journal, 2009, Volume: 33, Issue:2 Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; Humans; Liver Neoplasms; Lung Neoplasms; Male; Neoplasm Metastasis; Quinazolines; Recurrence; Treatment Outcome	2009
Successful and well-tolerated second line therapy with cetuximab, irinotecan, and raltitrexed in progressive liver disease due to metastatic colon cancer. Journal of gastrointestinal cancer, 2008, Volume: 39, Issue:1-4 Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colonic Neoplasms; Humans; Irinotecan; Liver Diseases; Liver Neoplasms; Male; Quinazolines; Thiophenes	2008
Severe photosensitivity reaction to vandetanib. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Sep-20, Volume: 27, Issue:27 Topics: Administration, Oral; Antineoplastic Agents; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Male; Middle Aged; Photosensitivity Disorders; Piperidines; Protein Kinase Inhibitors; Quinazolines	2009
Effect of gefitinib on warfarin antithrombotic activity. International journal of clinical oncology, 2009, Volume: 14, Issue:4 Topics: Aged; Anticoagulants; Antineoplastic Agents; Blood Coagulation; Carcinoma, Non-Small-Cell Lung; Drug Interactions; Female; Gefitinib; Humans; International Normalized Ratio; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Protein Kinase Inhibitors; Prothrombin Time; Quinazolines; Retrospective Studies; Time Factors; Warfarin	2009
Insulin-like growth factor-1 receptor inhibition induces a resistance mechanism via the epidermal growth factor receptor/HER3/AKT signaling pathway: rational basis for cotargeting insulin-like growth factor-1 receptor and epidermal growth factor receptor Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Sep-01, Volume: 15, Issue:17 Topics: Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Drug Synergism; ErbB Receptors; Gefitinib; Humans; Insulin; Liver Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinazolines; Receptor, ErbB-3; Receptor, IGF Type 1; RNA, Small Interfering; Signal Transduction; Sirolimus	2009
The selective Aurora B kinase inhibitor AZD1152 as a novel treatment for hepatocellular carcinoma. Journal of hepatology, 2010, Volume: 52, Issue:1 Topics: Animals; Aurora Kinase B; Aurora Kinases; Carcinoma, Hepatocellular; Cell Death; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Female; Histones; Humans; Liver Neoplasms; Mice; Mice, Nude; Organophosphates; Phosphorylation; Protein Serine-Threonine Kinases; Quinazolines; Treatment Outcome; Xenograft Model Antitumor Assays	2010
Raltitrexed and oxaliplatin hepatic arterial infusion for advanced colorectal cancer: a retrospective study. Anti-cancer drugs, 2010, Volume: 21, Issue:6 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Quinazolines; Retrospective Studies; Thiophenes	2010
Gefitinib as an effective therapy for advanced hepatocellular carcinoma with lung metastasis? Liver international : official journal of the International Association for the Study of the Liver, 2010, Volume: 30, Issue:10 Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; ErbB Receptors; Female; Gefitinib; Humans; Liver Neoplasms; Lung Neoplasms; Middle Aged; Molecular Targeted Therapy; Protein Kinase Inhibitors; Quinazolines; Tomography, X-Ray Computed; Treatment Outcome	2010
Successful treatment with erlotinib after gefitinib-related severe hepatotoxicity. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Jun-10, Volume: 28, Issue:17 Topics: Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Chemical and Drug Induced Liver Injury; Erlotinib Hydrochloride; Female; Gefitinib; Humans; Liver Neoplasms; Lung Neoplasms; Quinazolines	2010
Gastrin-releasing peptide promotes the growth of HepG2 cells via EGFR-independent ERK1/2 activation. Oncology reports, 2010, Volume: 24, Issue:2 Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Proliferation; Cells, Cultured; Enzyme Activation; ErbB Receptors; Gastrin-Releasing Peptide; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Indoles; Liver Neoplasms; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Quinazolines; Receptors, Bombesin	2010
Synthesis of new nonclassical acridines, quinolines, and quinazolines derived from dimedone for biological evaluation. Archiv der Pharmazie, 2010, Volume: 343, Issue:9 Topics: Acridines; Anti-Bacterial Agents; Antineoplastic Agents; Cyclohexanones; Gram-Negative Bacteria; Gram-Positive Bacteria; Hep G2 Cells; Humans; Inhibitory Concentration 50; Liver Neoplasms; Microbial Sensitivity Tests; Quinazolines; Quinolines	2010
Small-cell carcinoma with an epidermal growth factor receptor mutation in a never-smoker with gefitinib-responsive adenocarcinoma of the lung. Clinical lung cancer, 2010, Sep-01, Volume: 11, Issue:5 Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; ErbB Receptors; Female; Gefitinib; Humans; Liver Neoplasms; Lung Neoplasms; Mutation; Quinazolines	2010
The transforming growth factor-beta (TGF-β) mediates acquisition of a mesenchymal stem cell-like phenotype in human liver cells. Journal of cellular physiology, 2011, Volume: 226, Issue:5 Topics: Antigens, CD; Apoptosis; Apoptosis Regulatory Proteins; Cadherins; Carcinoma, Hepatocellular; Cell Proliferation; Cell Transdifferentiation; Cells, Cultured; ErbB Receptors; Gefitinib; Gene Expression Regulation; Hepatocytes; Humans; Liver; Liver Neoplasms; Mesenchymal Stem Cells; Neoplasm Invasiveness; Phenotype; Protein Kinase Inhibitors; Quinazolines; Recombinant Proteins; Signal Transduction; Snail Family Transcription Factors; Transcription Factors; Transforming Growth Factor beta1	2011
One patient with metastastic colorectal cancer successfully treated by combination of targeted agents after failure of chemotherapy. Chinese journal of cancer, 2010, Volume: 29, Issue:12 Topics: Adenocarcinoma; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Catheter Ablation; Cetuximab; Cytokine-Induced Killer Cells; Deoxycytidine; Disease-Free Survival; Drug Delivery Systems; ErbB Receptors; Fluorouracil; Gefitinib; Humans; Immunotherapy, Adoptive; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Multimodal Imaging; Neoplasm Staging; Oxaloacetates; Positron-Emission Tomography; Quality of Life; Quinazolines; Sigmoid Neoplasms; Tomography, X-Ray Computed	2010
Could HBx protein expression affect signal pathway inhibition by gefitinib or selumetinib, a MEK inhibitor, in hepatocellular carcinoma cell lines? Journal of Korean medical science, 2011, Volume: 26, Issue:2 Topics: Animals; Antineoplastic Agents; Benzimidazoles; beta Catenin; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Gefitinib; Humans; Liver Neoplasms; Mitogen-Activated Protein Kinase Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinazolines; Signal Transduction; Trans-Activators; Viral Regulatory and Accessory Proteins	2011
Trastuzumab and chemotherapy after the treatment failure of lapatinib for HER2-positive metastatic breast cancer. The Tokai journal of experimental and clinical medicine, 2010, Dec-20, Volume: 35, Issue:4 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Breast Neoplasms; Female; Humans; Lapatinib; Liver Neoplasms; Lung Neoplasms; Neoplasm Metastasis; Quinazolines; Receptor, ErbB-2; Trastuzumab; Treatment Failure	2010
Inhibitory effects of Zuo-Jin-Wan and its alkaloidal ingredients on activator protein 1, nuclear factor-κB, and cellular transformation in HepG2 cells. Fitoterapia, 2011, Volume: 82, Issue:4 Topics: Antineoplastic Agents, Phytogenic; Berberine; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Coptis; Drugs, Chinese Herbal; Evodia; Hep G2 Cells; Humans; Liver Neoplasms; NF-kappa B; Plant Extracts; Quinazolines; Tetradecanoylphorbol Acetate; Transcription Factor AP-1	2011
Multidisciplinary treatment with chemotherapy, targeted drug, and high-intensity focused ultrasound in advanced pancreatic carcinoma. Medical oncology (Northwood, London, England), 2012, Volume: 29, Issue:2 Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Deoxycytidine; Erlotinib Hydrochloride; Female; Gemcitabine; High-Intensity Focused Ultrasound Ablation; Humans; Liver Neoplasms; Middle Aged; Pancreatic Neoplasms; Quinazolines; Tomography, X-Ray Computed; Treatment Outcome	2012
[Adverse effects of new oncologic therapies]. Praxis, 2011, Jul-27, Volume: 100, Issue:15 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Bevacizumab; Cetuximab; Colonic Neoplasms; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Eruptions; ErbB Receptors; Erlotinib Hydrochloride; Everolimus; Facial Dermatoses; Humans; Indoles; Liver Neoplasms; Male; Middle Aged; Neoplasms; Niacinamide; Phenylurea Compounds; Pyridines; Pyrroles; Quinazolines; Sirolimus; Sorafenib; Sunitinib; Trastuzumab	2011
The tyrphostin AG1478 inhibits proliferation and induces death of liver tumor cells through EGF receptor-dependent and independent mechanisms. Biochemical pharmacology, 2011, Dec-01, Volume: 82, Issue:11 Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Drug Synergism; ErbB Receptors; Fetus; Gene Knockdown Techniques; Hepatocytes; Humans; Liver Neoplasms; Quinazolines; Tyrphostins	2011
Gefitinib resistance in HCC mahlavu cells: upregulation of CD133 expression, activation of IGF-1R signaling pathway, and enhancement of IGF-1R nuclear translocation. Journal of cellular physiology, 2012, Volume: 227, Issue:7 Topics: AC133 Antigen; Active Transport, Cell Nucleus; Antigens, CD; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Nucleus; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Glycoproteins; Humans; Liver Neoplasms; Neoplastic Stem Cells; Peptides; Phosphorylation; Protein Transport; Proto-Oncogene Proteins c-akt; Quinazolines; Receptor, IGF Type 1; Signal Transduction; Up-Regulation	2012
Mucin glycosylating enzyme GALNT2 regulates the malignant character of hepatocellular carcinoma by modifying the EGF receptor. Cancer research, 2011, Dec-01, Volume: 71, Issue:23 Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Erlotinib Hydrochloride; Female; Gene Knockdown Techniques; Glycosylation; Hep G2 Cells; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Mucins; N-Acetylgalactosaminyltransferases; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Polypeptide N-acetylgalactosaminyltransferase; Quinazolines; RNA, Messenger	2011
Hepatitis B virus large surface antigen promotes liver carcinogenesis by activating the Src/PI3K/Akt pathway. Cancer research, 2011, Dec-15, Volume: 71, Issue:24 Topics: Aged; Aged, 80 and over; Animals; Benzodioxoles; Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; Chlorocebus aethiops; Female; Hepatitis B Surface Antigens; Humans; Liver Neoplasms; Male; Mice; Mice, Nude; Middle Aged; Phosphatidylinositol 3-Kinases; Protein Kinase C-alpha; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins pp60(c-src); Quinazolines; RNA Interference; Signal Transduction; Vero Cells; Xenograft Model Antitumor Assays	2011
[Complete remission of multiple brain metastases of non-small cell lung cancer induced by gefitinib monotherapy]. Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2011, Volume: 187, Issue:12 Topics: Adenocarcinoma; Adult; Antineoplastic Agents; Brain Neoplasms; Cranial Irradiation; Drug Resistance, Neoplasm; Female; Gefitinib; Humans; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Magnetic Resonance Imaging; Neoplasm Staging; Quinazolines; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted	2011
Epithelial-mesenchymal transition predicts sensitivity to the dual IGF-1R/IR inhibitor OSI-906 in hepatocellular carcinoma cell lines. Molecular cancer therapeutics, 2012, Volume: 11, Issue:2 Topics: Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Synergism; Epithelial-Mesenchymal Transition; Erlotinib Hydrochloride; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Imidazoles; Insulin-Like Growth Factor II; Liver Neoplasms; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrazines; Quinazolines; Receptor, IGF Type 1; Receptor, Insulin; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction	2012
[A case of breast cancer liver metastases responding to lapatinib and capecitabine therapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:12 Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Carcinoma, Ductal, Breast; Deoxycytidine; Fatal Outcome; Female; Fluorouracil; Humans; Lapatinib; Liver Neoplasms; Middle Aged; Quinazolines	2011
The major vault protein mediates resistance to epidermal growth factor receptor inhibition in human hepatoma cells. Cancer letters, 2012, Jun-28, Volume: 319, Issue:2 Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cytokines; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Humans; Liver Neoplasms; Protein Kinase Inhibitors; Quinazolines; RNA, Small Interfering; Signal Transduction; Vault Ribonucleoprotein Particles	2012
Successful treatment of HER-2-positive metastatic apocrine carcinoma of the skin with lapatinib and capecitabine. Acta dermato-venereologica, 2012, Volume: 92, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biopsy; Capecitabine; Carcinoma; Deoxycytidine; Fluorouracil; Head and Neck Neoplasms; Humans; Immunohistochemistry; Lapatinib; Liver Neoplasms; Male; Middle Aged; Quinazolines; Receptor, ErbB-2; Scalp; Skin Neoplasms; Time Factors; Tomography, X-Ray Computed; Treatment Outcome	2012
Vandetanib, an inhibitor of VEGF receptor-2 and EGF receptor, suppresses tumor development and improves prognosis of liver cancer in mice. Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Jul-15, Volume: 18, Issue:14 Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Human Umbilical Vein Endothelial Cells; Humans; Liver Neoplasms; Mice; Mice, Nude; Neoplasms, Experimental; Phosphorylation; Piperidines; Prognosis; Quinazolines; Vascular Endothelial Growth Factor Receptor-2	2012
The role of surgery in patients with advanced gynaecological cancers participating in phase I clinical trials. European journal of gynaecological oncology, 2012, Volume: 33, Issue:2 Topics: Adenocarcinoma, Papillary; Adult; Afatinib; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carcinoma, Squamous Cell; Clinical Trials, Phase I as Topic; Female; Humans; Liver Neoplasms; Lung Neoplasms; Lymph Node Excision; Lymphatic Metastasis; Ovarian Neoplasms; Paclitaxel; Pelvic Neoplasms; Phthalazines; Piperazines; Quinazolines; Uterine Cervical Neoplasms	2012
Erlotinib and sorafenib in an orthotopic rat model of hepatocellular carcinoma. Journal of hepatology, 2012, Volume: 57, Issue:3 Topics: Animals; Apoptosis; Benzenesulfonates; Carcinoma, Hepatocellular; Cell Movement; Cell Survival; Drug Therapy, Combination; Endothelial Cells; ErbB Receptors; Erlotinib Hydrochloride; Hep G2 Cells; Humans; Liver Neoplasms; Neoplasm Transplantation; Neovascularization, Pathologic; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Quinazolines; Rats; RNA, Messenger; Sorafenib; Vascular Endothelial Growth Factor A	2012
Mechanisms involved in PGE2-induced transactivation of the epidermal growth factor receptor in MH1C1 hepatocarcinoma cells. Journal of experimental & clinical cancer research : CR, 2012, Sep-11, Volume: 31 Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Dinoprostone; Epidermal Growth Factor; ErbB Receptors; Gefitinib; Gene Expression Regulation, Neoplastic; Hepatocytes; Humans; Liver Neoplasms; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinazolines; Rats; Signal Transduction	2012
Impact of systematic EGFR and KRAS mutation evaluation on progression-free survival and overall survival in patients with advanced non-small-cell lung cancer treated by erlotinib in a French prospective cohort (ERMETIC project--part 2). Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2012, Volume: 7, Issue:10 Topics: Adenocarcinoma; Aged; Bone Neoplasms; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Disease-Free Survival; ErbB Receptors; Erlotinib Hydrochloride; Female; Follow-Up Studies; France; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Mutation; Neoplasm Staging; Prognosis; Prospective Studies; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Quinazolines; ras Proteins; Risk Factors; Survival Rate	2012
Gefitinib-induced hepatotoxicity in patients treated for non-small cell lung cancer. Onkologie, 2012, Volume: 35, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Chemical and Drug Induced Liver Injury; Female; Gefitinib; Humans; Liver Neoplasms; Middle Aged; Quinazolines; Treatment Outcome	2012
Evodiamine inhibits STAT3 signaling by inducing phosphatase shatterproof 1 in hepatocellular carcinoma cells. Cancer letters, 2013, Jan-28, Volume: 328, Issue:2 Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Enzyme Activation; Female; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Interleukin-6; Janus Kinase 2; Liver Neoplasms; Mice; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Quinazolines; RNA Interference; Signal Transduction; src-Family Kinases; STAT3 Transcription Factor; Tyrphostins; Xenograft Model Antitumor Assays	2013
Sorafenib-mediated targeting of the AAA⁺ ATPase p97/VCP leads to disruption of the secretory pathway, endoplasmic reticulum stress, and hepatocellular cancer cell death. Molecular cancer therapeutics, 2012, Volume: 11, Issue:12 Topics: Adenosine Triphosphatases; Antineoplastic Agents; Apoptosis; Autophagy; Carcinoma, Hepatocellular; Cell Line, Tumor; Endoplasmic Reticulum Stress; Hep G2 Cells; Humans; Liver Neoplasms; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Molecular Targeted Therapy; Niacinamide; Phenylurea Compounds; Phosphorylation; Protein Kinase Inhibitors; Quinazolines; Secretory Pathway; Sorafenib	2012
Inhibition of CIP2A determines erlotinib-induced apoptosis in hepatocellular carcinoma. Biochemical pharmacology, 2013, Feb-01, Volume: 85, Issue:3 Topics: Animals; Apoptosis; Autoantigens; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Erlotinib Hydrochloride; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Male; Membrane Proteins; Mice; Mice, Nude; Neoplasms, Experimental; Protein Kinase Inhibitors; Protein Phosphatase 2; Proto-Oncogene Proteins c-akt; Quinazolines; RNA, Small Interfering	2013
In-vitro growth inhibition of chemotherapy and molecular targeted agents in hepatocellular carcinoma. Anti-cancer drugs, 2013, Volume: 24, Issue:3 Topics: Alanine; alpha-Fetoproteins; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Carcinoma, Hepatocellular; Cetuximab; Dasatinib; Doxorubicin; Drug Screening Assays, Antitumor; Epothilones; Gefitinib; Humans; Indoles; Inhibitory Concentration 50; Liver Neoplasms; Niacinamide; Phenylurea Compounds; Piperidines; Pyridones; Pyrimidines; Pyrroles; Quinazolines; Sorafenib; Sunitinib; Thiazoles; Triazines	2013
Gefitinib and gemcitabine coordinately inhibited the proliferation of cholangiocarcinoma cells. Anticancer research, 2012, Volume: 32, Issue:12 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma, Non-Small-Cell Lung; Cell Growth Processes; Cell Line, Tumor; Cholangiocarcinoma; Deoxycytidine; ErbB Receptors; Gefitinib; Gemcitabine; Hep G2 Cells; Humans; Liver Neoplasms; Lung Neoplasms; Mice; Mice, Nude; Quinazolines; Random Allocation; Signal Transduction; Xenograft Model Antitumor Assays	2012
Synthesis and antitumor activity of novel 2-(1-substituted-piperidin-4-ylamino)quinazolines as antitumor agents. Yao xue xue bao = Acta pharmaceutica Sinica, 2012, Volume: 47, Issue:9 Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Cell Line, Tumor; Drug Screening Assays, Antitumor; Inhibitory Concentration 50; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Quinazolines	2012
[Lapatinib is useful for metastatic breast cancer patients who cannot be treated with trastuzumab-report of a case]. Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:12 Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Biopsy, Needle; Breast Neoplasms; Combined Modality Therapy; Female; Humans; Lapatinib; Liver Neoplasms; Mastectomy; Neoplasm Staging; Quinazolines; Trastuzumab	2012
EGFR is a transducer of the urokinase receptor initiated signal that is required for in vivo growth of a human carcinoma. Cancer cell, 2002, Volume: 1, Issue:5 Topics: Blotting, Northern; Carcinoma, Hepatocellular; Cell Division; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Integrin beta1; Liver Neoplasms; Mitogen-Activated Protein Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quinazolines; Receptors, Cell Surface; Receptors, Fibronectin; Receptors, Urokinase Plasminogen Activator; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tumor Cells, Cultured; Tyrphostins	2002
Raltitrexed treatment promotes systemic inflammatory reaction in patients with colorectal carcinoma. British journal of cancer, 2002, Sep-09, Volume: 87, Issue:6 Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; C-Reactive Protein; Colorectal Neoplasms; Cross-Sectional Studies; Fatigue; Female; Fever; Fluorouracil; Humans; Inflammation; Interleukin-6; Liver Neoplasms; Longitudinal Studies; Lung Neoplasms; Male; Middle Aged; Quinazolines; Thiophenes; Thymidylate Synthase; Tumor Necrosis Factor-alpha	2002
Severe liver dysfunction after raltitrexed administration in an HCV-positive colorectal cancer patient. Cancer investigation, 2003, Volume: 21, Issue:1 Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Chemical and Drug Induced Liver Injury; Colectomy; Colonic Neoplasms; Combined Modality Therapy; Enzyme Inhibitors; Hepatitis C, Chronic; Humans; Interferon-alpha; Liver Function Tests; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Quinazolines; Thiophenes; Viremia	2003
ZD1839, a selective epidermal growth factor receptor tyrosine kinase inhibitor, shows antimetastatic activity using a hepatocellular carcinoma model. Molecular cancer therapeutics, 2003, Volume: 2, Issue:6 Topics: Animals; Antineoplastic Agents; Blotting, Western; Carcinoma, Hepatocellular; Cell Division; Cell Line, Tumor; Cell Movement; Dose-Response Relationship, Drug; ErbB Receptors; Female; Gefitinib; Liver Neoplasms; Mice; Neoplasm Metastasis; Neoplasm Transplantation; Phosphorylation; Quinazolines; Signal Transduction	2003
[The effect of IRESSA on H22 mouse hepatocellular carcinoma]. Zhonghua yi xue za zhi, 2004, Apr-17, Volume: 84, Issue:8 Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cisplatin; Disease Models, Animal; Gefitinib; Liver Neoplasms; Mice; Quinazolines; Random Allocation; Treatment Outcome	2004
Suppression of hepatocellular carcinoma growth in mice by the alkaloid coccidiostat halofuginone. European journal of cancer (Oxford, England : 1990), 2004, Volume: 40, Issue:9 Topics: alpha-Fetoproteins; Animals; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Line, Tumor; Coccidiostats; Drug Screening Assays, Antitumor; Humans; Interferon-gamma; Interleukin-2; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Piperidines; Quinazolines; Quinazolinones	2004
[Recurrence of non-small cell lung cancer after successful treatment with gefitinib--report of three cases]. Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:8 Topics: Adenocarcinoma; Adult; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Drug Administration Schedule; ErbB Receptors; Female; Gefitinib; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Quinazolines	2004
In vivo videomicroscopy reveals differential effects of the vascular-targeting agent ZD6126 and the anti-angiogenic agent ZD6474 on vascular function in a liver metastasis model. Angiogenesis, 2004, Volume: 7, Issue:2 Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Blood Vessels; Cell Line, Transformed; Disease Models, Animal; Female; Liver Neoplasms; Mice; Mice, SCID; Microscopy, Video; Neoplasm Metastasis; Neoplasm Transplantation; Neovascularization, Pathologic; Organophosphorus Compounds; Piperidines; Quinazolines	2004
Targeting the epidermal growth factor receptor by gefitinib for treatment of hepatocellular carcinoma. Journal of hepatology, 2004, Volume: 41, Issue:6 Topics: Antineoplastic Agents; Apoptosis; bcl-X Protein; Carcinoma, Hepatocellular; Cell Cycle; Cell Division; Cell Line, Tumor; Dose-Response Relationship, Drug; Down-Regulation; Drug Administration Schedule; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Gefitinib; Humans; Liver Neoplasms; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Quinazolines; Receptors, Somatomedin; RNA, Messenger	2004
Gefitinib, an EGFR inhibitor, prevents hepatocellular carcinoma development in the rat liver with cirrhosis. Hepatology (Baltimore, Md.), 2005, Volume: 41, Issue:2 Topics: Alkylating Agents; Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Diethylnitrosamine; ErbB Receptors; Gefitinib; Liver Cirrhosis; Liver Neoplasms; Male; Quinazolines; Rats; Rats, Wistar; Signal Transduction; Transforming Growth Factor alpha	2005
Antitumor effect of Gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, combined with cytotoxic agent on murine hepatocellular carcinoma. World journal of gastroenterology, 2005, Mar-07, Volume: 11, Issue:9 Topics: Animals; Antineoplastic Agents; Blood Cell Count; Body Weight; Carcinoma, Hepatocellular; Cisplatin; Cytotoxins; Drug Therapy, Combination; ErbB Receptors; Female; Gefitinib; Liver Neoplasms; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Organ Size; Quinazolines; Spleen; Thymus Gland	2005
Absence of epidermal growth factor receptor exon 18-21 mutation in hepatocellular carcinoma. Cancer letters, 2005, Jun-16, Volume: 224, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Base Sequence; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; DNA Mutational Analysis; DNA, Neoplasm; ErbB Receptors; Exons; Female; Gefitinib; Humans; Liver Neoplasms; Male; Middle Aged; Molecular Sequence Data; Point Mutation; Quinazolines; Sequence Analysis, DNA	2005
Erlotinib induces cell cycle arrest and apoptosis in hepatocellular cancer cells and enhances chemosensitivity towards cytostatics. Journal of hepatology, 2005, Volume: 43, Issue:4 Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Division; Cell Line, Tumor; Doxorubicin; Drug Synergism; ErbB Receptors; Erlotinib Hydrochloride; Humans; Liver Neoplasms; Quinazolines	2005
EGFR blockade by cetuximab alone or as combination therapy for growth control of hepatocellular cancer. Biochemical pharmacology, 2005, Nov-25, Volume: 70, Issue:11 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Division; Cell Line, Tumor; Cetuximab; Cisplatin; Dose-Response Relationship, Drug; Doxorubicin; Drug Evaluation, Preclinical; Drug Therapy, Combination; ErbB Receptors; Erlotinib Hydrochloride; Fatty Acids, Monounsaturated; Fluvastatin; Gene Expression Regulation, Neoplastic; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Liver Neoplasms; Quinazolines; Tyrphostins	2005
ZD6474 inhibits proliferation and invasion of human hepatocellular carcinoma cells. Biochemical pharmacology, 2006, Feb-14, Volume: 71, Issue:4 Topics: Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Adhesion; Cell Adhesion Molecules; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Extracellular Matrix Proteins; Humans; Immunoprecipitation; Inhibitory Concentration 50; Kalinin; Liver Neoplasms; Neoplasm Invasiveness; Piperidines; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Time Factors	2006
[A case of lung adenocarcinoma of the lung with disappearance of brain metastasis by re-treatment with gefitinib]. Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2005, Volume: 43, Issue:11 Topics: Adenocarcinoma; Adult; Antineoplastic Agents; Brain; Brain Neoplasms; Combined Modality Therapy; Cranial Irradiation; Gefitinib; Humans; Liver Neoplasms; Lung Neoplasms; Male; Quinazolines; Remission Induction; Retreatment; Tomography, X-Ray Computed	2005
Activation of MEK/ERK and PI3K/Akt pathways by fibronectin requires integrin alphav-mediated ADAM activity in hepatocellular carcinoma: a novel functional target for gefitinib. Cancer science, 2006, Volume: 97, Issue:2 Topics: ADAM Proteins; Animals; Carcinoma, Hepatocellular; Drug Therapy, Combination; ErbB Receptors; Fibronectins; Gefitinib; Integrin alphaV; Liver Neoplasms; MAP Kinase Kinase Kinases; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinazolines; Signal Transduction	2006
[Molecular therapy for HCC?]. Zeitschrift fur Gastroenterologie, 2006, Volume: 44, Issue:2 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Clinical Trials as Topic; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Erlotinib Hydrochloride; Female; Follow-Up Studies; Humans; Liver Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Probability; Protein Kinase Inhibitors; Quinazolines; Survival Analysis; Treatment Outcome	2006
Gefitinib and the modulation of the signaling pathways downstream of epidermal growth factor receptor in human liver cancer cells. Journal of gastroenterology, 2006, Volume: 41, Issue:2 Topics: ErbB Receptors; Gefitinib; Humans; Liver Neoplasms; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Protein Kinase Inhibitors; Quinazolines; Signal Transduction; Transforming Growth Factor alpha; Tumor Cells, Cultured	2006
[Contribution to acneiform eruptions by epidermal growth factor receptor inhibitors]. Actas dermo-sifiliograficas, 2006, Volume: 97, Issue:2 Topics: Acneiform Eruptions; Adenocarcinoma; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Colonic Neoplasms; Disease Susceptibility; Drug Eruptions; ErbB Receptors; Gefitinib; Humans; Liver Neoplasms; Lung Neoplasms; Male; Neoplasm Proteins; Quinazolines; Staphylococcal Skin Infections; Superinfection	2006
[Inhibitory effects of iressa on hepatocellular carcinoma Hep-3B and HepG2 cell xenografts in nude mice]. Ai zheng = Aizheng = Chinese journal of cancer, 2006, Volume: 25, Issue:4 Topics: Animals; Antineoplastic Agents; Body Weight; Cell Line, Tumor; Dose-Response Relationship, Drug; Female; Gefitinib; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Quinazolines; Random Allocation; Xenograft Model Antitumor Assays	2006
Halofuginone suppresses the lung metastasis of chemically induced hepatocellular carcinoma in rats through MMP inhibition. Neoplasia (New York, N.Y.), 2006, Volume: 8, Issue:4 Topics: Angiogenesis Inhibitors; Animals; Carcinoma, Hepatocellular; Liver Neoplasms; Lung Neoplasms; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Matrix Metalloproteinases, Membrane-Associated; Neoplasm Metastasis; Piperidines; Quinazolines; Quinazolinones; Rats; Rats, Inbred F344	2006
Amphiregulin contributes to the transformed phenotype of human hepatocellular carcinoma cells. Cancer research, 2006, Jun-15, Volume: 66, Issue:12 Topics: Aged; Amphiregulin; Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Growth Processes; Cell Line, Tumor; Cell Transformation, Neoplastic; EGF Family of Proteins; ErbB Receptors; Glycoproteins; Humans; Intercellular Signaling Peptides and Proteins; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Quinazolines; RNA, Small Interfering; Signal Transduction; Up-Regulation	2006
Blockage of epidermal growth factor receptor by quinazoline tyrosine kinase inhibitors suppresses growth of human hepatocellular carcinoma. Cancer letters, 2007, Apr-08, Volume: 248, Issue:1 Topics: Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Flow Cytometry; Humans; Liver Neoplasms; Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinazolines	2007
Signaling pathways involved in the inhibition of epidermal growth factor receptor by erlotinib in hepatocellular cancer. World journal of gastroenterology, 2006, Aug-28, Volume: 12, Issue:32 Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; DNA, Complementary; ErbB Receptors; Erlotinib Hydrochloride; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; Humans; Insulin-Like Growth Factor I; Liver Neoplasms; Poly A; Protein Kinase Inhibitors; Quinazolines	2006
Impact of IGF-1R/EGFR cross-talks on hepatoma cell sensitivity to gefitinib. International journal of cancer, 2006, Dec-01, Volume: 119, Issue:11 Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Proliferation; ErbB Receptors; Flow Cytometry; Gefitinib; Humans; Insulin-Like Growth Factor II; Liver Neoplasms; Quinazolines; Receptor Cross-Talk; Receptor, IGF Type 1; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction	2006
Molecular basis for sensitivity and acquired resistance to gefitinib in HER2-overexpressing human gastric cancer cell lines derived from liver metastasis. British journal of cancer, 2006, Dec-04, Volume: 95, Issue:11 Topics: Animals; Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Drug Resistance, Neoplasm; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gefitinib; Humans; Immunohistochemistry; Liver Neoplasms; Male; Mice; Mice, Nude; Neoplasms, Experimental; Quinazolines; Receptor, ErbB-2; Stomach Neoplasms	2006
Clinical benefit of readministration of gefitinib for initial gefitinib-responders with non-small cell lung cancer. BMC cancer, 2007, Mar-20, Volume: 7 Topics: Administration, Oral; Antineoplastic Agents; Bone Neoplasms; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Cohort Studies; Combined Modality Therapy; Drug Administration Schedule; Female; Follow-Up Studies; Gefitinib; Humans; Liver Neoplasms; Lung Neoplasms; Male; Quinazolines; Retrospective Studies; Treatment Outcome	2007
Papulopustular drug eruption due to an epidermal growth factor receptor inhibitors, erlotinib and cetuximab. Dermatology online journal, 2007, Jan-27, Volume: 13, Issue:1 Topics: Adenocarcinoma; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Cetuximab; Drug Eruptions; ErbB Receptors; Erlotinib Hydrochloride; Follow-Up Studies; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Protein Kinase Inhibitors; Quinazolines; Rectal Neoplasms; Rosacea	2007
Fulminant hepatic failure secondary to erlotinib. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2007, Volume: 5, Issue:8 Topics: Administration, Oral; Aged; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Erlotinib Hydrochloride; Female; Humans; Liver Failure, Acute; Liver Neoplasms; Lung Neoplasms; Protein Kinase Inhibitors; Quinazolines	2007
Prostaglandin E2 upregulates EGF-stimulated signaling in mitogenic pathways involving Akt and ERK in hepatocytes. Journal of cellular physiology, 2008, Volume: 214, Issue:2 Topics: Animals; Carcinoma, Hepatocellular; Cell Culture Techniques; Cells, Cultured; Culture Media, Serum-Free; Cyclin D; Cyclins; Dinoprostone; DNA; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Gefitinib; Gene Expression Regulation; Hepatocytes; Liver Neoplasms; Male; Pertussis Toxin; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinazolines; Rats; Rats, Wistar; Signal Transduction; Tyrphostins	2008
Leukocytoclastic vasculitis during treatment with the oral EGFR tyrosine kinase inhibitor erlotinib. Annals of oncology : official journal of the European Society for Medical Oncology, 2007, Volume: 18, Issue:9 Topics: Adenocarcinoma; Administration, Oral; Aged; Antineoplastic Agents; Carcinoma, Hepatocellular; Erlotinib Hydrochloride; Female; Humans; Leg; Liver Neoplasms; Male; Middle Aged; Pancreatic Neoplasms; Quinazolines; Vasculitis, Leukocytoclastic, Cutaneous	2007
Capecitabine plus erlotinib in gemcitabine-refractory advanced pancreatic cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Oct-20, Volume: 25, Issue:30 Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; ErbB Receptors; Erlotinib Hydrochloride; Female; Fluorouracil; Gemcitabine; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Pancreatic Neoplasms; Prognosis; Quinazolines; Salvage Therapy; Survival Rate	2007
Development of sorafenib and other molecularly targeted agents in hepatocellular carcinoma. Cancer, 2008, Jan-15, Volume: 112, Issue:2 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzenesulfonates; Bevacizumab; Carcinoma, Hepatocellular; Clinical Trials as Topic; ErbB Receptors; Humans; Indoles; Liver Neoplasms; Niacinamide; Phenylurea Compounds; Pyridines; Pyrroles; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Sorafenib; Sunitinib; Vascular Endothelial Growth Factor A	2008
[Analysis of therapeutic efficacy in 49 patients with advanced non-small cell cancer treated with gefitinib]. Zhonghua zhong liu za zhi [Chinese journal of oncology], 2007, Volume: 29, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Exanthema; Female; Gefitinib; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Protein Kinase Inhibitors; Quinazolines; Remission Induction; Survival Rate; Vomiting	2007
EGFR and VEGFR as potential target for biological therapies in HCC cells. Cancer letters, 2008, Apr-18, Volume: 262, Issue:2 Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Delivery Systems; ErbB Receptors; Gefitinib; Humans; Liver Neoplasms; Piperidines; Quinazolines; Receptors, Vascular Endothelial Growth Factor	2008
Multiplexed cell signaling analysis of human breast cancer applications for personalized therapy. Journal of proteome research, 2008, Volume: 7, Issue:4 Topics: Breast Neoplasms; Cluster Analysis; Erlotinib Hydrochloride; Female; Humans; Intracellular Signaling Peptides and Proteins; Lasers; Liver Neoplasms; Microdissection; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Proteomics; Proto-Oncogene Proteins c-akt; Quinazolines; Receptor Protein-Tyrosine Kinases; Signal Transduction	2008
Increased vascular-endothelial growth factor (VEGF) tumor expression and response to epidermal growth factor receptor (EGF-R) inhibitor erlotinib in non-small cell lung cancer (NSCLC). Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2008, Volume: 3, Issue:3 Topics: Adult; Carcinoma, Non-Small-Cell Lung; DNA, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Fatal Outcome; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Lung Neoplasms; Mutation; Protein Kinase Inhibitors; Quinazolines; Retrospective Studies; Vascular Endothelial Growth Factor A	2008
Chronic myeloid leukemia following the treatment of rectal adenocarcinoma. Medical oncology (Northwood, London, England), 2008, Volume: 25, Issue:4 Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Deoxycytidine; Fluorouracil; Fusion Proteins, bcr-abl; Humans; In Situ Hybridization, Fluorescence; Irinotecan; Leucovorin; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Liver Neoplasms; Male; Neoplasms, Second Primary; Organoplatinum Compounds; Oxaliplatin; Philadelphia Chromosome; Quinazolines; Rectal Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Thiophenes	2008
Epithelial-to-mesenchymal transition and integrin-linked kinase mediate sensitivity to epidermal growth factor receptor inhibition in human hepatoma cells. Cancer research, 2008, Apr-01, Volume: 68, Issue:7 Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cadherins; Carcinoma, Hepatocellular; Cell Line, Tumor; Cetuximab; Enzyme Activation; Epithelial Cells; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; Humans; Insulin-Like Growth Factor II; Liver Neoplasms; Mesoderm; Mice; Mice, Inbred BALB C; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Quinazolines; Receptor, IGF Type 1; STAT3 Transcription Factor; Vimentin	2008
New therapeutic strategies for patients with gastrointestinal malignancies using biochemical modulation of fluorouracil. JAMA, 1995, Jan-18, Volume: 273, Issue:3 Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Colonic Neoplasms; Fatal Outcome; Fluorouracil; Folic Acid; Folic Acid Antagonists; Gastrointestinal Neoplasms; Gene Expression Regulation, Enzymologic; Humans; Interferon-alpha; Leucovorin; Liver Neoplasms; Male; Middle Aged; Prognosis; Quinazolines; RNA, Messenger; RNA, Neoplasm; Thymidylate Synthase	1995
Regulatory implications of peroxisome proliferation: an industrial perspective. Annals of the New York Academy of Sciences, 1996, Dec-27, Volume: 804 Topics: Animals; Humans; Industry; Liver Neoplasms; Liver Neoplasms, Experimental; Microbodies; Quinazolines; Risk Assessment; Social Control, Formal; Species Specificity	1996
Raltitrexed (Tomudex): an alternative drug for patients with colorectal cancer and 5-fluorouracil associated cardiotoxicity. British journal of cancer, 1998, Volume: 77, Issue:6 Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Electrocardiography; Female; Fluorouracil; Heart; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Quinazolines; Sigmoid Neoplasms; Thiophenes; Thymidylate Synthase	1998
Cross-talk between epidermal growth factor receptor and c-Met signal pathways in transformed cells. The Journal of biological chemistry, 2000, Mar-24, Volume: 275, Issue:12 Topics: Animals; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Epidermal Growth Factor; ErbB Receptors; Hepatocyte Growth Factor; Humans; Liver Neoplasms; Phosphorylation; Protein Binding; Proto-Oncogene Proteins c-met; Quinazolines; Rats; Receptor Cross-Talk; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrphostins	2000
Synergistic efficacy of 3n-butyrate and 5-fluorouracil in human colorectal cancer xenografts via modulation of DNA synthesis. Gastroenterology, 2001, Volume: 120, Issue:4 Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers; Butyrates; Cell Differentiation; Cell Division; Colorectal Neoplasms; Dihydrouracil Dehydrogenase (NADP); DNA; Drug Synergism; Female; Fluorouracil; Glucose; Humans; Liver Neoplasms; Male; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Organoplatinum Compounds; Oxaliplatin; Oxidoreductases; Protein-Tyrosine Kinases; Quinazolines; RNA, Messenger; Thiophenes; Thymidylate Synthase; Transplantation, Heterologous	2001
Safe administration of irinotecan, oxaliplatin and raltitrexed in a DPD-deficient patient with metastatic colon cancer. Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:4 Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Dihydrouracil Dehydrogenase (NADP); Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Oxidoreductases; Quinazolines; Thiophenes	2001
Role of substrate depletion in the inhibition of thymidylate biosynthesis by the dihydrofolate reductase inhibitor trimetrexate in cultured hepatoma cells. Cancer research, 1990, Jul-01, Volume: 50, Issue:13 Topics: Carcinoma, Hepatocellular; Folic Acid; Liver Neoplasms; Pteroylpolyglutamic Acids; Quinazolines; Thymidine Monophosphate; Thymidylate Synthase; Thymine Nucleotides; Trimetrexate; Tumor Cells, Cultured	1990
Serial serum AFP heterogeneity changes in patients with hepatocellular carcinoma during chemotherapy. Cancer chemotherapy and pharmacology, 1986, Volume: 17, Issue:2 Topics: alpha-Fetoproteins; Carcinoma, Hepatocellular; Concanavalin A; Folic Acid; Humans; Liver Neoplasms; Quinazolines	1986
Serum vitamin B12 levels in patients with primary hepatocellular carcinoma during treatment with CB3717. Journal of surgical oncology, 1987, Volume: 34, Issue:2 Topics: Adult; Aged; alpha-Fetoproteins; Carcinoma, Hepatocellular; Female; Folic Acid; Follow-Up Studies; Humans; L-Lactate Dehydrogenase; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Quinazolines; Vitamin B 12	1987
Induction of remission in hepatocellular carcinoma with a new thymidylate synthase inhibitor, CB3717. A phase II study. Journal of hepatology, 1987, Volume: 4, Issue:3 Topics: Adult; Aged; alpha-Fetoproteins; Carcinoma, Hepatocellular; Drug Evaluation; Female; Folic Acid; Follow-Up Studies; Humans; Liver Neoplasms; Male; Middle Aged; Quinazolines; Remission Induction	1987
Intestinal alkaline phosphatase isoenzyme in patients with primary liver cancer during treatment with N10-propargyl 5, 8-dideazafolic acid (CB 3717). Journal of surgical oncology, 1988, Volume: 38, Issue:2 Topics: Adult; Aged; Alkaline Phosphatase; Aspartate Aminotransferases; Female; Folic Acid; gamma-Glutamyltransferase; Humans; Intestinal Mucosa; Isoenzymes; Liver Neoplasms; Male; Middle Aged; Quinazolines; Time Factors	1988
Trimetrexate: predictors of severe or life-threatening toxic effects. Journal of the National Cancer Institute, 1988, Oct-19, Volume: 80, Issue:16 Topics: Antineoplastic Agents; Blood Proteins; Drug Evaluation; Female; Folic Acid Antagonists; Humans; Liver Neoplasms; Male; Protein Binding; Quinazolines; Trimetrexate	1988
Inhibition of the growth of human hepatocellular carcinoma in vitro and in athymic mice by a quinazoline inhibitor of thymidylate synthase, CB3717. British journal of cancer, 1986, Volume: 53, Issue:3 Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Deoxyuridine; Dose-Response Relationship, Drug; Folic Acid; Humans; In Vitro Techniques; Liver Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Quinazolines; Thymidine	1986
A pleomorphic hepatocellular carcinoma with biochemical features of fibrolamellar hepatocellular carcinoma. Journal of surgical oncology, 1986, Volume: 32, Issue:2 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Combined Modality Therapy; Doxorubicin; Etoposide; Female; Folic Acid; Humans; Liver Neoplasms; Neurotensin; Quinazolines; Vitamin B 12	1986
The apparent induction of thymidylate synthetase by amethopterin. Annals of the New York Academy of Sciences, 1971, Nov-30, Volume: 186 Topics: Animals; Aspartic Acid; Benzoates; Carcinoma, Hepatocellular; Enzyme Induction; Folic Acid; Hepatectomy; Liver; Liver Neoplasms; Liver Regeneration; Methotrexate; Methyltransferases; Neoplasms, Experimental; Quinazolines; Rats; Thymine Nucleotides; Uracil Nucleotides	1971