Compounds > quinazolines
Page last updated: 2024-08-21

quinazolines and Cancer of Cervix

quinazolines has been researched along with Cancer of Cervix in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (5.00)18.2507
2000's8 (20.00)29.6817
2010's25 (62.50)24.3611
2020's5 (12.50)2.80

Authors

AuthorsStudies
Akudugu, JM; Hamid, MB; Serafin, AM1
Aghajanian, C; Chui, MH; Gardner, GJ; Gordhandas, SB; Grisham, RN; Henson, C; Iyer, G; Manning-Geist, B; Moore, KN; Sonoda, Y1
Atangana, AF; Fotso, GW; Happi, EN; Lenta, BN; Mbahbou, GTB; Ngadjui, BT; Noulala, CGT; Ouete, JLN; Sewald, N; Stammler, HG1
Bharathan, R; Chuai, Y; Dai, G; Li, Y; Otter, SJ; Rizzuto, I; Stewart, A; Wang, A; Zhang, X1
Chen, WJ; Ding, Y; Liu, H; Liu, YM; Sun, HL; Xu, YY; Ying, SP1
Lai, Y; Sun, X; Tao, L; Wang, Q; Xu, C; Zhang, X; Zhao, Y1
Elinoff, JM; Kleiner, DE; Lee, JM; Peer, CJ; Pratt, D; Solomon, MA; Suffredini, DA1
Carty, K; Davidson, S; Dive, C; Jayson, GC; McCartney, E; Paul, J; Rai, D; Simpson, K; Symonds, P; Taylor, S; Tugwood, J; West, C; Zhou, C1
Gandhi, AK; Jagadesan, P; Julka, PK; Kumar, S; Rath, GK; Sharma, DN1
Alves, FV; Carmo, CC; Erlich, F; Ferreira, CG; Grazziotin, R; Mamede, M; Moralez, G; Nogueira-Rodrigues, A; Small, IA; Triginelli, SA; Viegas, C1
Kurzrock, R; Parker, BA; Schwab, R; Yan, M1
Feng, ZZ; Hu, JG; Huang, YJ; Li, D; Liu, F; Liu, G; Tang, J; Wang, QY; Zhang, YY1
Li, XY; Liu, L; Xie, XM; Zhou, C1
Franckena, M; Kraan, J; Sleijfer, S; van Doorn, L; van Meerten, E; Westermann, A; Wiemer, E1
Schmidt, C1
Choi, HE; Choi, JH; Kim, JY; Lee, HH; Lee, KT; Lee, YS; Shin, DH; Shin, JS1
Ahn, SE; Bae, DS; Cho, YJ; Choi, JJ; Choi, YL; Jung, K; Kim, BG; Kim, S; Lee, JW; Oh, DY; Oh, E; Park, WY; Song, JY; Song, S1
Banerjee, S; Carty, K; Davidson, S; Dive, C; Flubacher, M; Gourley, C; Hudson, E; Jackson, D; Jankowska, P; Lord, R; McCartney, E; McCormack, M; Paul, J; Powell, M; Rai, D; Reed, N; Symonds, RP; West, CML1
Tewari, KS1
Du, J; Hu, H; Li, C; Li, H; Li, Y; Wang, L; Yang, H; Zhang, Z1
Arora, H; Biswas, S; Gandhi, G; Naseem, A; Perwez, A; Qureshi, R; Rizvi, MA; Wajid, S1
Che, T; Chen, AC; Gu, LQ; Huang, ZL; Huang, ZS; Li, D; Ou, TM; Shan, C; Tan, JH; Wang, YQ; Yan, JW; Yao, PF1
Baltazar, F; Barbosa, AM; Cardoso-Carneiro, D; Cury, FP; de Paula, FE; Evangelista, AF; Granja, S; Longatto-Filho, A; Marques, F; Martinho, O; Miranda-Gonçalves, V; Moreira, MA; Reis, RM; Scapulatempo-Neto, C; Silva-Oliveira, R; Zanon, M1
Camisão, C; do Carmo, CC; Erlich, F; Ferreira, CG; Fontão, K; Herchenhorn, D; Lima, R; Martins, RG; Moralez, GM; Nogueira-Rodrigues, A; Small, IA; Viegas, C1
Chang, KY; Chang, WC; Chen, BK; Lee, MY; Shen, MR; Su, WC; Wang, WL1
Lee, YC; Mannel, R; Schilder, RJ; Sill, MW1
Alber, JA; Ding, J; Mas Lopez, L; Monk, BJ; Oaknin, A; Pandite, LN; Stutts, MW; Tarpin, C; Termrungruanglert, W; Zarba, JJ1
Zhang, L; Zhang, S1
Iida, K; Ishikawa, M; Katagiri, A; Kobayashi, H; Miyazaki, K; Nakayama, K; Nakayama, S; Otsuki, Y; Rahman, M; Rahman, MT; Yeasmin, S1
Easthope, E; Emery, A; Glover, DM; Jones, DO; Lawrence, S; Scaerou, F; Sorrell, DA; Stockdale, M; Zheleva, D1
Diefendorf, LP; Jette, DF; Mohammed, A; Mondal, S; Moses, MA; Searleman, SA; Stevens, DA; Wilton, KM; Woodworth, CD1
Monk, BJ; Pandite, LN1
Baird, RD; Barton, DP; Kaye, SB; Khan, AZ; Moreno, V; Vitfell-Pedersen, J; Yap, TA1
Ikejima, T; Onodera, S; Tashiro, S; Wu, LJ; Zhang, QH; Zhang, Y1
Allen, S; Marker, D; Michael, E; Nees, M; Smith, L; Woodworth, CD1
Birle, DC; Hedley, DW1
Carrasco, AT; Chaigneau, L; Extra, JM; Fabbro, M; Floquet, A; Gladieff, L; Goncalves, A; Lhommé, C; Viens, P1
Al Moustafa, AE1
Aherne, GW; Hardcastle, A; Jackman, AL; Kelland, LR; Kimbell, R1
Albanell, J; Baselga, J; Bos, M; Fry, DW; Kim, YM; Mendelsohn, J1

Reviews

1 review(s) available for quinazolines and Cancer of Cervix

ArticleYear
Vascular endothelial growth factor (VEGF) targeting therapy for persistent, recurrent, or metastatic cervical cancer.
    The Cochrane database of systematic reviews, 2021, 03-04, Volume: 3

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antineoplastic Agents; Bevacizumab; Bias; Brachytherapy; Combined Modality Therapy; Confidence Intervals; Female; Gastric Fistula; Gastrointestinal Hemorrhage; Humans; Hypertension; Indazoles; Intestinal Fistula; Intestinal Perforation; Lapatinib; Middle Aged; Neoplasm Recurrence, Local; Progression-Free Survival; Pyridines; Pyrimidines; Quality of Life; Quinazolines; Randomized Controlled Trials as Topic; Sulfonamides; Thromboembolism; Uterine Cervical Neoplasms; Vascular Endothelial Growth Factor A; Young Adult

2021

Trials

9 trial(s) available for quinazolines and Cancer of Cervix

ArticleYear
Dynamics of circulating vascular endothelial growth factor-A predict benefit from antiangiogenic cediranib in metastatic or recurrent cervical cancer patients.
    British journal of clinical pharmacology, 2019, Volume: 85, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Disease Progression; Drug Monitoring; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Progression-Free Survival; Quinazolines; Uterine Cervical Neoplasms; Vascular Endothelial Growth Factor A; Young Adult

2019
Role of gefitinib in patients with recurrent or metastatic cervical carcinoma ineligible or refractory to systemic chemotherapy: first study from Asia.
    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2013, Volume: 23, Issue:4

    Topics: Adult; Antineoplastic Agents; Disease-Free Survival; Female; Gefitinib; Humans; India; Middle Aged; Neoplasm Recurrence, Local; Prospective Studies; Quinazolines; Uterine Cervical Neoplasms

2013
Phase 2 trial of erlotinib combined with cisplatin and radiotherapy in patients with locally advanced cervical cancer.
    Cancer, 2014, Apr-15, Volume: 120, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Chemoradiotherapy; Cisplatin; ErbB Receptors; Erlotinib Hydrochloride; Female; Humans; Middle Aged; Neoplasm Staging; Protein Kinase Inhibitors; Quinazolines; Uterine Cervical Neoplasms

2014
Phase I study of cisplatin, hyperthermia, and lapatinib in patients with recurrent carcinoma of the uterine cervix in a previously irradiated area.
    The oncologist, 2015, Volume: 20, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Combined Modality Therapy; Dose-Response Relationship, Drug; Female; Humans; Hyperthermia, Induced; Lapatinib; Neoplasm Recurrence, Local; Quinazolines; Treatment Outcome; Uterine Cervical Neoplasms

2015
Cediranib combined with carboplatin and paclitaxel in patients with metastatic or recurrent cervical cancer (CIRCCa): a randomised, double-blind, placebo-controlled phase 2 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:15

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Disease-Free Survival; Double-Blind Method; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Paclitaxel; Quinazolines; Uterine Cervical Neoplasms

2015
Phase I trial of erlotinib combined with cisplatin and radiotherapy for patients with locally advanced cervical squamous cell cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Oct-01, Volume: 14, Issue:19

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Carcinoma, Squamous Cell; Cisplatin; Cohort Studies; Combined Modality Therapy; Erlotinib Hydrochloride; Female; Humans; Middle Aged; Quinazolines; Radiation Oncology; Time Factors; Treatment Outcome; Uterine Cervical Neoplasms

2008
A phase II trial of erlotinib in recurrent squamous cell carcinoma of the cervix: a Gynecologic Oncology Group Study.
    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2009, Volume: 19, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; ErbB Receptors; Erlotinib Hydrochloride; Female; Humans; Middle Aged; Prognosis; Protein Kinase Inhibitors; Quinazolines; Survival Rate; Treatment Outcome; Uterine Cervical Neoplasms

2009
Phase II, open-label study of pazopanib or lapatinib monotherapy compared with pazopanib plus lapatinib combination therapy in patients with advanced and recurrent cervical cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Aug-01, Volume: 28, Issue:22

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Drug Delivery Systems; Female; Humans; Indazoles; Lapatinib; Middle Aged; Protein Kinase Inhibitors; Pyrimidines; Quinazolines; Recurrence; Retreatment; Sulfonamides; Uterine Cervical Neoplasms

2010
A phase II trial to evaluate gefitinib as second- or third-line treatment in patients with recurring locoregionally advanced or metastatic cervical cancer.
    Gynecologic oncology, 2008, Volume: 108, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; ErbB Receptors; Female; Gefitinib; Humans; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Quinazolines; Uterine Cervical Neoplasms

2008

Other Studies

30 other study(ies) available for quinazolines and Cancer of Cervix

ArticleYear
Selective therapeutic benefit of X-rays and inhibitors of EGFR, PI3K/mTOR, and Bcl-2 in breast, lung, and cervical cancer cells.
    European journal of pharmacology, 2021, Dec-05, Volume: 912

    Topics: Aniline Compounds; Breast Neoplasms; Cell Line; Cell Survival; ErbB Receptors; Female; Humans; Imidazoles; Lung Neoplasms; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Quinazolines; Quinolines; Radiation Tolerance; Sulfonamides; TOR Serine-Threonine Kinases; Tyrphostins; Uterine Cervical Neoplasms; X-Rays

2021
Pre-clinical activity of the oral DNA-PK inhibitor, peposertib (M3814), combined with radiation in xenograft models of cervical cancer.
    Scientific reports, 2022, 01-19, Volume: 12, Issue:1

    Topics: Animals; Chemoradiotherapy; DNA-Activated Protein Kinase; Female; HeLa Cells; Humans; Mice; Pyridazines; Quinazolines; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays

2022
Soyauxinine, a New Indolopyridoquinazoline Alkaloid from the Stem Bark of
    Molecules (Basel, Switzerland), 2022, Feb-07, Volume: 27, Issue:3

    Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Female; Humans; Indoles; Plant Bark; Plant Extracts; Pyridines; Quinazolines; Rutaceae; Tumor Cells, Cultured; Uterine Cervical Neoplasms

2022
Outcomes of icotinib combined with concurrent chemoradiotherapy in locally advanced cervical cancer.
    Neoplasma, 2021, Volume: 68, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Cisplatin; Crown Ethers; Female; Humans; Neoplasm Staging; Quinazolines; Uterine Cervical Neoplasms

2021
Cx32 inhibits TNFα-induced extrinsic apoptosis with and without EGFR suppression.
    Oncology reports, 2017, Volume: 38, Issue:5

    Topics: Afatinib; Apoptosis; Connexins; Cycloheximide; Doxycycline; ErbB Receptors; Female; Gap Junction beta-1 Protein; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Inhibitor of Apoptosis Proteins; Phosphorylation; Quinazolines; Survivin; Tumor Necrosis Factor-alpha; Uterine Cervical Neoplasms

2017
Pulmonary tumor thrombotic microangiopathy and pulmonary veno-occlusive disease in a woman with cervical cancer treated with cediranib and durvalumab.
    BMC pulmonary medicine, 2018, Jul-11, Volume: 18, Issue:1

    Topics: Antibodies, Monoclonal; Autopsy; Carcinoma, Squamous Cell; Fatal Outcome; Female; Humans; Lung; Lung Neoplasms; Middle Aged; Neoplastic Cells, Circulating; Pulmonary Veno-Occlusive Disease; Quinazolines; Thrombotic Microangiopathies; Uterine Cervical Neoplasms

2018
HER2 aberrations in cancer: implications for therapy.
    Cancer treatment reviews, 2014, Volume: 40, Issue:6

    Topics: Ado-Trastuzumab Emtansine; Adult; Afatinib; Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Female; Gene Amplification; Gene Expression Regulation, Neoplastic; Humans; Lapatinib; Male; Maytansine; Molecular Targeted Therapy; Mutation; Neoplasms; Peritoneal Neoplasms; Protein Kinase Inhibitors; Quinazolines; Receptor, ErbB-2; Trastuzumab; Up-Regulation; Uterine Cervical Neoplasms

2014
Preliminary evaluation of the in vitro efficacy of 1, 2-di (quinazolin-4-yl) diselane against SiHa cervical cancer cells.
    Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:15

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Proliferation; Drug Screening Assays, Antitumor; Female; Flow Cytometry; Humans; In Vitro Techniques; L-Lactate Dehydrogenase; Organoselenium Compounds; Quinazolines; Tumor Cells, Cultured; Uterine Cervical Neoplasms

2014
The role of raltitrexed/cisplatin with concurrent radiation therapy in treating advanced cervical cancer.
    European review for medical and pharmacological sciences, 2014, Volume: 18, Issue:22

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Female; Follow-Up Studies; Humans; Middle Aged; Quinazolines; Survival Rate; Thiophenes; Treatment Outcome; Uterine Cervical Neoplasms

2014
Cediranib aims for a comeback.
    Journal of the National Cancer Institute, 2015, Volume: 107, Issue:3

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Clinical Trials as Topic; Female; Humans; Myelodysplastic Syndromes; National Cancer Institute (U.S.); Neoplasm Recurrence, Local; Ovarian Neoplasms; Phthalazines; Piperazines; Protein-Tyrosine Kinases; Quinazolines; United Kingdom; United States; Uterine Cervical Neoplasms; Vaginal Fistula; Vascular Endothelial Growth Factor A; Weight Loss

2015
Resveratrol analogue (E)-8-acetoxy-2-[2-(3,4-diacetoxyphenyl)ethenyl]-quinazoline induces G₂/M cell cycle arrest through the activation of ATM/ATR in human cervical carcinoma HeLa cells.
    Oncology reports, 2015, Volume: 33, Issue:5

    Topics: Ataxia Telangiectasia Mutated Proteins; Carcinoma; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle Checkpoints; Cell Division; Checkpoint Kinase 1; Checkpoint Kinase 2; Cyclin B1; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; DNA Damage; Female; G2 Phase; HeLa Cells; Humans; Phosphorylation; Protein Kinases; Quinazolines; Resveratrol; Signal Transduction; Stilbenes; Tumor Suppressor Protein p53; Up-Regulation; Uterine Cervical Neoplasms

2015
HER2 as a novel therapeutic target for cervical cancer.
    Oncotarget, 2015, Nov-03, Volume: 6, Issue:34

    Topics: Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Female; HeLa Cells; Humans; Lapatinib; Mice; Mice, Inbred BALB C; Middle Aged; Molecular Targeted Therapy; Quinazolines; Receptor, ErbB-2; Trastuzumab; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays

2015
Clinical implications for cediranib in advanced cervical cancer.
    The Lancet. Oncology, 2015, Volume: 16, Issue:15

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Female; Humans; Neoplasm Recurrence, Local; Paclitaxel; Quinazolines; Uterine Cervical Neoplasms

2015
MicroRNA-221 targets PTEN to reduce the sensitivity of cervical cancer cells to gefitinib through the PI3K/Akt signaling pathway.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:3

    Topics: 3' Untranslated Regions; Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Cell Survival; Chromones; Enzyme Inhibitors; Female; Gefitinib; HeLa Cells; Humans; MicroRNAs; Morpholines; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; PTEN Phosphohydrolase; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Uterine Cervical Neoplasms

2016
Mutation analysis of EGFR and its correlation with the HPV in Indian cervical cancer patients.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents; Cell Line, Tumor; DNA Mutational Analysis; ErbB Receptors; Exons; Female; Gefitinib; HeLa Cells; Human papillomavirus 16; Human papillomavirus 18; Humans; India; Middle Aged; Mutation; Papillomavirus Infections; Protein Kinase Inhibitors; Quinazolines; Uterine Cervical Neoplasms

2016
Design, Synthesis, and Evaluation of Isaindigotone Derivatives To Downregulate c-myc Transcription via Disrupting the Interaction of NM23-H2 with G-Quadruplex.
    Journal of medicinal chemistry, 2017, 02-23, Volume: 60, Issue:4

    Topics: Alkaloids; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Down-Regulation; Drug Design; Female; G-Quadruplexes; Gene Expression Regulation, Neoplastic; Humans; NM23 Nucleoside Diphosphate Kinases; Proto-Oncogene Proteins c-myc; Quinazolines; Transcription, Genetic; Transcriptional Activation; Uterine Cervical Neoplasms

2017
HER Family Receptors are Important Theranostic Biomarkers for Cervical Cancer: Blocking Glucose Metabolism Enhances the Therapeutic Effect of HER Inhibitors.
    Theranostics, 2017, Volume: 7, Issue:3

    Topics: Acrylamides; Adenocarcinoma; Antimetabolites; Antineoplastic Agents; Biomarkers, Tumor; Diagnostic Tests, Routine; Drug Resistance, Neoplasm; ErbB Receptors; Female; Glucose; Humans; Lapatinib; Quinazolines; Theranostic Nanomedicine; Therapeutic Uses; Uterine Cervical Neoplasms

2017
Epidermal growth factor-activated aryl hydrocarbon receptor nuclear translocator/HIF-1{beta} signal pathway up-regulates cyclooxygenase-2 gene expression associated with squamous cell carcinoma.
    The Journal of biological chemistry, 2009, Apr-10, Volume: 284, Issue:15

    Topics: Active Transport, Cell Nucleus; Aryl Hydrocarbon Receptor Nuclear Translocator; Carcinoma, Squamous Cell; Cell Line, Tumor; Cobalt; Cyclooxygenase 2; Epidermal Growth Factor; Female; Humans; Microscopy, Fluorescence; Models, Biological; Promoter Regions, Genetic; Quinazolines; RNA, Messenger; Tyrphostins; Uterine Cervical Neoplasms

2009
ZM447439, the Aurora kinase B inhibitor, suppresses the growth of cervical cancer SiHa cells and enhances the chemosensitivity to cisplatin.
    The journal of obstetrics and gynaecology research, 2011, Volume: 37, Issue:6

    Topics: Antineoplastic Agents; Aurora Kinase B; Aurora Kinases; Benzamides; Cell Line, Tumor; Cisplatin; Drug Resistance, Neoplasm; Drug Synergism; Female; Humans; Molecular Targeted Therapy; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Quinazolines; Uterine Cervical Neoplasms

2011
EGFR gene amplification is related to adverse clinical outcomes in cervical squamous cell carcinoma, making the EGFR pathway a novel therapeutic target.
    British journal of cancer, 2011, Jul-26, Volume: 105, Issue:3

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Animals; Carcinoma, Squamous Cell; Child; Child, Preschool; ErbB Receptors; Female; Gene Amplification; Genes, erbB-1; Humans; Mice; Mice, Nude; Middle Aged; Molecular Targeted Therapy; Mutation; Quinazolines; Tyrphostins; Up-Regulation; Uterine Cervical Neoplasms

2011
A novel cell-based, high-content assay for phosphorylation of Lats2 by Aurora A.
    Journal of biomolecular screening, 2011, Volume: 16, Issue:8

    Topics: Antibodies, Phospho-Specific; Antineoplastic Agents; Aurora Kinases; Automation, Laboratory; Centrosome; Female; HeLa Cells; High-Throughput Screening Assays; Humans; Microtubule-Associated Proteins; Mitosis; Molecular Imaging; Organophosphates; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Quinazolines; Small Molecule Libraries; Tumor Suppressor Proteins; Uterine Cervical Neoplasms

2011
Inhibition of the epidermal growth factor receptor by erlotinib prevents immortalization of human cervical cells by Human Papillomavirus type 16.
    Virology, 2011, Dec-05, Volume: 421, Issue:1

    Topics: Apoptosis; Cell Transformation, Viral; Cervix Uteri; Down-Regulation; ErbB Receptors; Erlotinib Hydrochloride; Female; Gene Expression Regulation, Viral; Human papillomavirus 16; Humans; Oncogene Proteins, Viral; Papillomavirus E7 Proteins; Papillomavirus Infections; Protein Kinase Inhibitors; Quinazolines; Repressor Proteins; Signal Transduction; Tumor Cells, Cultured; Uterine Cervical Neoplasms

2011
Survival data from a phase II, open-label study of pazopanib or lapatinib monotherapy in patients with advanced and recurrent cervical cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-20, Volume: 29, Issue:36

    Topics: Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Pyrimidines; Quinazolines; Sulfonamides; Uterine Cervical Neoplasms

2011
The role of surgery in patients with advanced gynaecological cancers participating in phase I clinical trials.
    European journal of gynaecological oncology, 2012, Volume: 33, Issue:2

    Topics: Adenocarcinoma, Papillary; Adult; Afatinib; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carcinoma, Squamous Cell; Clinical Trials, Phase I as Topic; Female; Humans; Liver Neoplasms; Lung Neoplasms; Lymph Node Excision; Lymphatic Metastasis; Ovarian Neoplasms; Paclitaxel; Pelvic Neoplasms; Phthalazines; Piperazines; Quinazolines; Uterine Cervical Neoplasms

2012
Atypical apoptosis in L929 cells induced by evodiamine isolated from Evodia rutaecarpa.
    Journal of Asian natural products research, 2004, Volume: 6, Issue:1

    Topics: Adenocarcinoma; Animals; Apoptosis; Breast Neoplasms; Cell Survival; Evodia; Female; Fibrosarcoma; Fruit; Humans; Leukemia, Monocytic, Acute; Leukocytes, Mononuclear; Melanoma; Mice; Plant Extracts; Quinazolines; Tumor Cells, Cultured; Uterine Cervical Neoplasms

2004
Inhibition of the epidermal growth factor receptor increases expression of genes that stimulate inflammation, apoptosis, and cell attachment.
    Molecular cancer therapeutics, 2005, Volume: 4, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Bromodeoxyuridine; Cell Cycle; Cell Line, Tumor; Collagen; DNA; DNA, Complementary; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; ErbB Receptors; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Immunoprecipitation; Inflammation; NF-kappa B; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Oligonucleotide Probes; Phosphorylation; Polymerase Chain Reaction; Quinazolines; RNA; Tyrosine; Up-Regulation; Uterine Cervical Neoplasms

2005
Signaling interactions of rapamycin combined with erlotinib in cervical carcinoma xenografts.
    Molecular cancer therapeutics, 2006, Volume: 5, Issue:10

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Interactions; Epidermal Growth Factor; Erlotinib Hydrochloride; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Mice; Mice, SCID; Neoplasm Transplantation; Neoplasms, Experimental; Phosphorylation; Quinazolines; Ribosomal Protein S6; Signal Transduction; Sirolimus; Transplantation, Heterologous; Uterine Cervical Neoplasms

2006
Human cervical carcinomas and EGF-R tyrosine kinase inhibitors.
    Gynecologic oncology, 2008, Volume: 109, Issue:2

    Topics: Carcinoma, Squamous Cell; Clinical Trials, Phase II as Topic; Enzyme Inhibitors; ErbB Receptors; Female; Gefitinib; Humans; Quinazolines; Uterine Cervical Neoplasms

2008
Relationships between resistance to cisplatin and antifolates in sensitive and resistant tumour cell lines.
    European journal of cancer (Oxford, England : 1990), 1995, Volume: 31A, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Resistance; Female; Folic Acid; Folic Acid Antagonists; Humans; Male; Ovarian Neoplasms; Quinazolines; Testicular Neoplasms; Thiophenes; Tumor Cells, Cultured; Uterine Cervical Neoplasms

1995
PD153035, a tyrosine kinase inhibitor, prevents epidermal growth factor receptor activation and inhibits growth of cancer cells in a receptor number-dependent manner.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:11

    Topics: Adenocarcinoma; Breast Neoplasms; Carcinoma, Squamous Cell; Colonic Neoplasms; Enzyme Inhibitors; ErbB Receptors; Female; Genes, erbB-2; Humans; Male; Phosphorylation; Prostatic Neoplasms; Quinazolines; Receptor Protein-Tyrosine Kinases; Receptor, ErbB-2; Recombinant Proteins; Transfection; Uterine Cervical Neoplasms; Vulvar Neoplasms

1997