Page last updated: 2024-08-21

quinazolines and Body Weight

quinazolines has been researched along with Body Weight in 98 studies

Research

Studies (98)

TimeframeStudies, this research(%)All Research%
pre-199035 (35.71)18.7374
1990's11 (11.22)18.2507
2000's26 (26.53)29.6817
2010's24 (24.49)24.3611
2020's2 (2.04)2.80

Authors

AuthorsStudies
Atanasov, AG; Dirsch, VM; Heiß, EH; Hou, X; Malainer, C; Wang, K; Wang, L1
Lin, JY; Yeh, TH1
Kibaly, C; Law, PY; Liu, JG; Loh, HH; McGarrah, PW; Song, KY; Wang, YJ; Xu, C; Zhang, L1
Liu, L; Ni, H; Ren, F; Ren, J; Shen, T; Wei, H; Wei, J; Xu, S; Zhou, X1
Aroor, AR; Bender, SB; Demarco, VG; Garro, M; Hayden, MR; Johnson, MS; Mugerfeld, I; Nistala, R; Salam, M; Sowers, JR; Whaley-Connell, A1
Charbonnel, B; Dejager, S; Schweizer, A1
Beijnen, JH; Huitema, AD; Knapen, LM; Lankheet, NA; Schellens, JH; Steeghs, N1
Chaudhary, R; Nityanand, S; Singh, A1
Cheng, Z; Li, P; Liu, Z; Zhu, Q1
Alpini, G; DeMorrow, S; Frampton, G; Galindo, C; McMillin, M; Standeford, H; Thompson, M; Whittington, E1
Balansky, R; Camoirano, A; D'Agostini, F; De Flora, S; Ganchev, G; Iltcheva, M; Izzotti, A; La Maestra, S; Longobardi, M; Micale, RT; Steele, VE1
Hansen, G; Hansen, HH; Jelsing, J; Klein, T; Mark, M; Paulsen, S; Vrang, N1
Altera, KP; Ames, MM; Buhrow, SA; Bunin, DI; Davis, M; Ji, J; Kinders, RJ; Lawrence, SM; Parman, T; Rausch, LL; Reid, JM; Samuelsson, SJ; Walden, C1
Iseri, K; Iyoda, M; Kuno, Y; Matsumoto, K; Saito, T; Shibata, T; Shindo-Hirai, Y; Suzuki, T; Wada, Y; Yamamoto, Y1
Hu, J; Li, X; Liang, D; Liang, G; Lin, F; Qian, Y; Wang, J; Xu, Z; Zeng, C; Zhong, P1
Holmes, GL; Isaev, D; Isaeva, E; Lunko, O; Lushnikova, I; Maximyuk, O; Romanov, A; Skibo, GG; Tian, C; Zapukhliak, O1
Butchbach, ME; Harris, AW1
Al-Huniti, N; Henningsson, A; Li, J; Masson, E; Tang, W1
Fleckner, J; Larsen, LK; Larsen, PJ; Lykkegaard, K; Sauerberg, P; Wassermann, K; Wulff, EM1
Chen, K; Lei, Q; Shi, J; Yan, J; Yang, D; Zhang, Y; Zhao, J; Zhao, X1
Chen, XG; Feng, ZQ; Li, J; Liu, Y; Meng, Y1
Greufe, S; Hayward, R; Hydock, DS; Schneider, CM; Wonders, KY1
Gurubasavarajaswamy, PM; Nagaranavile, KS; Parameshwaran, T; Raghavendra, NM1
Arnold, LL; Chen, B; Cohen, SM; Le, XC; Pennington, KL; Suzuki, S1
Beck-Nielsen, H; Byrjalsen, I; Christiansen, C; Henriksen, K; Karsdal, MA; Larsen, LK; Madsen, AN; Nielsen, RH1
Hare, KJ; Hartmann, B; Holst, JJ; Poulsen, SS; Rasmussen, AR; Thim, L; Viby, NE1
Boockvar, JA; Edgar, MA; Karampelas, I; Luther, N; Souliopoulos, EP; Souweidane, MM1
Deng, HW; Hu, CP; Li, JZ; Li, XH; Li, YJ; Liao, MC; Peng, J; Xiao, L; Zhang, YS1
Alauddin, MM; Balatoni, J; Borne, A; Brammer, D; Fukumitsu, N; Gelovani, JG; Jackson, J; Mawlawi, O; Mukhopadhyay, U; Ogawa, K; Tian, M; Uthamanthil, R; Wendt, R; Yang, B1
Akhtar, S; Al-Farsi, O; Benter, IF; Chandrasekhar, B; Dhaunsi, GS; Yousif, MH1
Cao, S; Gao, H; Jiang, X; Pang, Z; Xi, Z; Yang, Z; Zhang, S1
Araki, E; Dugi, K; Hayashi, N; Horie, Y; Inagaki, N; Kawamori, R; Sarashina, A; Thiemann, S; von Eynatten, M; Watada, H; Woerle, HJ1
Alapati, V; Manjula, SN; Noolvi, MN; Pallavi, KJ; Patel, HM; Satyanarayana, SV; Tippeswamy, BS1
Cetkovic-Cvrlje, M; Liu, XP; Roers, BA; Schonhoff, D; Uckun, FM; Waurzyniak, B1
Alaoui-Jamali, MA; Jean-Claude, BJ; Matheson, SL; McNamee, JP; Tari, AM; Wang, T1
Guan, ZZ; Jiang, WQ; Lin, TY; Wang, SS; Xiang, YQ; Zhang, L1
Akhtar, S; Benter, IF; Yousif, MH1
Li, X; Li, Y; Lu, QY; Yuan, SJ; Zhao, QC; Zhu, BD1
Ajiki, T; Digiovanni, J; Kawamoto, T; Kiguchi, K; Ruffino, L1
Awad, H; Hurwitz, H; Klitzman, B; Ko, J; Ross, J1
Esmat, AY; Gawad, SM; Ibrahim, AM; Mohamed, MA; Refaie, FM1
Doetkotte, R; Kiianmaa, K; Opitz, K; Winterhoff, H1
Jahng, Y; Jeon, TW; Jeong, HG; Jeong, TC; Jin, CH; Jun, IH; Kim, GH; Lee, DJ; Lee, KB; Lee, SK1
Matsunaga, N; Nakamura, K; Taguchi, E; Takahashi, K; Tsunoda, H; Yamamoto, A1
Li, JQ; Lin, XJ; Xu, L; Zhang, YJ1
Guo, F; Letrent, SP; Sharma, A1
Hare, KJ; Hartmann, B; Holst, JJ; Kissow, H; Poulsen, SS1
Conklin, E; Dwyer-Nield, LD; Eckhardt, SG; Fritz, JM; Gustafson, DL; Iwata, KK; Kane, S; Malkinson, AM; Redente, EF; Shroyer, RJ; Tucker, C; Zerbe, LK1
Mitchell, HC; Pettinger, WA1
Flax, JS; Havard, CW; Khokhar, AM1
Carter, DC; Farah, DA; Lorimer, AR; Mills, PR; Rae, AP; Russell, RI1
Eich, R; Mookherjee, S; Smulyan, H; Vardan, S1
Keshavarz, K; McDougald, LR1
Männer, K; Matuschka, FR1
Morgan, TO; Myers, JB; Walker, JN1
Bilgili, SF; Hess, JB; Pinion, JL1
Bilgili, SF; Eckman, MK; Hess, JB; Pinion, JL1
Chapman, HD; Hacker, AB1
Amyx, H; Boytos, CM; Duch, DS; Ferone, R; Smith, GK; Wilson, HR1
Buhr, RJ; Christensen, KD; Goodman, TN; Twining, PF; Wyatt, CL; Zimmermann, NG1
Hirawa, N; Numabe, A; Takada, S; Uehara, Y; Yagi, S1
Fukuhara, Y; Hisatomi, A; Ishida, H; Mitamura, T; Murato, K; Ohara, K; Takahashi, Y1
Egashira, K; Ichiki, T; Katoh, M; Takeshita, A; Usui, M1
Arnold, LD; Baker, DA; Barbacci, EG; Davis, JA; Doty, JL; Iwata, KK; Morin, MJ; Moyer, JD; Pollack, VA; Pustilnik, LR; Savage, DM; Sloan, DE; Smolarek, TA; Tsaparikos, KE; Vaidya, MP1
Aherne, GW; Brunton, L; Clarke, SJ; Farrugia, DC; Jackman, AL1
Goto, T; Ikuma, K; Kawamura, I; Mutoh, S; Seki, J; Shimoshige, Y; Takakura, S; Yamamoto, T1
Kris, MG; Miller, VA; Scher, HI; Sirotnak, FM; Zakowski, MF1
Hoshikuma, K; Kamiya, T; Kizaki, M; Kobayashi, Y; Nakano, Y; Yokoo, Y1
Bolli, P; Simpson, FO; Wood, AJ1
Beretta-Piccoli, C; Glück, Z; Keusch, G; Meier, A; Weidmann, P1
Mukerjee, SS; Mukherjee, SK; Roy, AK; Sethi, N; Srivastava, GN1
Banerjee, BN; Ivins, NJ; Ludwig, BJ; Sofia, RD1
Edgar, SA; Flanagan, C2
De Guzman de Guzman, D; Mendlowitz, M; Vlachakis, ND1
Bolli, P; Simpson, FO1
Holleschau, AM; Rathbun, WB; Tao, RV1
Adams, MH; Cabel, MC; Colberg, M; Izat, AL; Reiber, MA; Skinner, JT; Stilborn, HL; Waldroup, PW1
Dolan, TT1
Kast, A; Kobayashi, S; Nishimura, M; Tsunenari, Y1
Conder, GA; Folz, SD; Lee, BL; Nowakowski, LH1
Enueme, JE; Grant, RJ; Halvorson, JC; Waibel, PE1
Damron, BL; Fell, RV; Grant, RJ; Hebert, JA; Hellwig, HM; Johnson, ZB; Primo, RA; Siccardi, FJ; Waldroup, PW1
Behr, KP; Lüders, H; Plate, C1
McDougald, LR1
Grant, RJ; Quarles, CL; Spencer, GK; Waibel, PE; Waldroup, PW1
Hirogami, M; Minami, M; Morii, K; Nomura, A; Saito, H; Saito, I; Sano, M; Tochihara, M; Togashi, H; Yoshioka, M1
Kondo, Y; Tanabe, A; Toriumi, T1
Campos, JA; Cangiano, JL; Ramirez-Gonzalez, R; Ramirez-Muzo, O; Trevino, A1
Fujimura, H; Hiramatsu, Y; Nozaki, M; Tamura, Y; Tsurumi, K1
Inoue, I; Ishida, R; Kowa, Y; Nurimoto, S; Ochiai, T1
Allison, ME; Dargie, HJ; Gray, MJ; Kennedy, AC1
Davidov, M; Finnerty, FA; Fotiu, S; Mroczek, WJ1
Philips, FS; Sodergren, JE; Sternberg, SS; Vidal, P1
Glenn, EM; Lyster, SC; Rohloff, NA1
Gunstone, RF; Njemo, D; Sabuka, EM; Shani, HG; Wing, AJ1
Hutchison, DJ; Schmid, FA; Shimoyama, M1
De Fina, V; Setnikar, I1

Reviews

1 review(s) available for quinazolines and Body Weight

ArticleYear
Combination therapy with DPP-4 inhibitors and insulin in patients with type 2 diabetes mellitus: what is the evidence?
    Hospital practice (1995), 2013, Volume: 41, Issue:2

    Topics: Adamantane; Body Weight; Diabetes Complications; Diabetes Mellitus, Type 2; Dipeptides; Dipeptidyl-Peptidase IV Inhibitors; Disease Progression; Drug Therapy, Combination; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Linagliptin; Nitriles; Piperidines; Purines; Pyrazines; Pyrrolidines; Quinazolines; Renal Insufficiency, Chronic; Sitagliptin Phosphate; Triazoles; Uracil; Vildagliptin

2013

Trials

8 trial(s) available for quinazolines and Body Weight

ArticleYear
Long-term safety of linagliptin monotherapy in Japanese patients with type 2 diabetes.
    Diabetes, obesity & metabolism, 2013, Volume: 15, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Asian People; Blood Glucose; Body Mass Index; Body Weight; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Inositol; Linagliptin; Male; Middle Aged; Purines; Quinazolines; Time Factors

2013
Population pharmacokinetics of a HER2 tyrosine kinase inhibitor CP-724,714 in patients with advanced malignant HER2 positive solid tumors.
    Cancer chemotherapy and pharmacology, 2007, Volume: 60, Issue:6

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Body Weight; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Female; Humans; Liver Neoplasms; Middle Aged; Models, Biological; Multicenter Studies as Topic; Neoplasms; Nonlinear Dynamics; Quinazolines; Receptor, ErbB-2; Tissue Distribution

2007
Comparison of three adrenoreceptor blocking agents in patients with cirrhosis and portal hypertension.
    Gut, 1984, Volume: 25, Issue:1

    Topics: Atenolol; Blood Pressure; Body Weight; Clinical Trials as Topic; Female; Heart Rate; Humans; Hypertension, Portal; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Portal Vein; Prazosin; Propranolol; Quinazolines

1984
Effects of prazosin in patients with hypertension.
    Clinical pharmacology and therapeutics, 1976, Volume: 20, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Body Weight; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Piperazines; Placebos; Pulse; Quinazolines; Renin; Time Factors

1976
Treatment of essential hypertension with trimazosin, a new vasodilator agent.
    Current therapeutic research, clinical and experimental, 1975, Volume: 17, Issue:6

    Topics: Adult; Body Weight; Clinical Trials as Topic; Female; Humans; Hypertension; Male; Middle Aged; Piperazines; Placebos; Pulse; Quinazolines; Vasodilator Agents

1975
Experience with prazosin in the treatment of hypertension.
    Postgraduate medicine, 1975, Volume: Spec No

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Body Weight; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Physical Exertion; Piperazines; Posture; Pulse; Quinazolines

1975
The effects of metolazone in the long-term treatment of essential hypertension.
    Current therapeutic research, clinical and experimental, 1974, Volume: 16, Issue:8

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Body Weight; Clinical Trials as Topic; Diuretics; Humans; Hypertension; Male; Middle Aged; Placebos; Quinazolines; Sulfonamides; Time Factors

1974
Antihypertensive efficacy of metolazone.
    Clinical pharmacology and therapeutics, 1974, Volume: 16, Issue:2

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Body Weight; Chlorthalidone; Diuretics; Edema; Female; Humans; Hypertension; Hypokalemia; Male; Middle Aged; Placebos; Quinazolines

1974

Other Studies

89 other study(ies) available for quinazolines and Body Weight

ArticleYear
Evodiamine Lowers Blood Lipids by Up-Regulating the PPARγ/ABCG1 Pathway in High-Fat-Diet-Fed Mice.
    Journal of natural products, 2021, 12-24, Volume: 84, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 1; Bile Acids and Salts; Body Weight; Diet, High-Fat; Lipids; Liver; Mice; Plant Extracts; PPAR gamma; Quinazolines

2021
Rutaecarpine administration inhibits cancer cell growth in allogenic TRAMP-C1 prostate cancer mice correlating with immune balance in vivo.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 139

    Topics: Animals; Antigens, CD; Antineoplastic Agents, Phytogenic; Body Weight; Cachexia; Cell Line, Tumor; Cell Transformation, Neoplastic; Cytokines; Dose-Response Relationship, Drug; Indole Alkaloids; Lymphocyte Count; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Organ Size; Prostatic Neoplasms; Quinazolines; Spleen; Th1-Th2 Balance; Tumor Necrosis Factor-alpha

2021
Src-dependent phosphorylation of μ-opioid receptor at Tyr
    EMBO molecular medicine, 2017, Volume: 9, Issue:11

    Topics: Animals; Behavior, Animal; Benzodioxoles; Body Weight; HEK293 Cells; Humans; Locomotion; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Naloxone; Narcotic Antagonists; Phosphorylation; Proto-Oncogene Proteins c-fyn; Quinazolines; Receptors, Opioid, mu; RNA Interference; RNA, Small Interfering; src-Family Kinases; Tyrosine

2017
Combination of berberine and evodiamine inhibits intestinal cholesterol absorption in high fat diet induced hyperlipidemic rats.
    Lipids in health and disease, 2017, Dec-11, Volume: 16, Issue:1

    Topics: Administration, Oral; Animals; Apolipoprotein B-48; Berberine; Body Weight; Cholesterol, LDL; Coptis; Diet, High-Fat; Drug Combinations; Evodia; Gene Expression Regulation; Hyperlipidemias; Hypolipidemic Agents; Intestinal Absorption; Lipid Metabolism; Liver; Male; Membrane Transport Proteins; Quinazolines; Rats; Rats, Sprague-Dawley; Sitosterols; Sterol O-Acyltransferase; Sterol O-Acyltransferase 2; Triglycerides

2017
Dipeptidylpeptidase inhibition is associated with improvement in blood pressure and diastolic function in insulin-resistant male Zucker obese rats.
    Endocrinology, 2013, Volume: 154, Issue:7

    Topics: Animals; Blood Pressure; Body Weight; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Eating; Insulin Resistance; Linagliptin; Male; Myocardium; Nitric Oxide Synthase Type III; Purines; Quinazolines; Rats; Rats, Zucker; Sarcoplasmic Reticulum Calcium-Transporting ATPases

2013
Plasma concentrations of tyrosine kinase inhibitors imatinib, erlotinib, and sunitinib in routine clinical outpatient cancer care.
    Therapeutic drug monitoring, 2014, Volume: 36, Issue:3

    Topics: Aged; Antineoplastic Agents; Benzamides; Body Weight; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Drug Monitoring; Erlotinib Hydrochloride; Female; Gastric Acid; Half-Life; Histamine H2 Antagonists; Humans; Imatinib Mesylate; Indoles; Male; Middle Aged; Neoplasms; Outpatients; Piperazines; Protein Kinase Inhibitors; Proton Pump Inhibitors; Pyrimidines; Pyrroles; Quinazolines; Sunitinib; Tandem Mass Spectrometry

2014
Successful management of acute bleeding in essential thrombocythemia using automated cell separator.
    Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis, 2014, Volume: 50, Issue:1

    Topics: Administration, Oral; Adolescent; Automation; Blood Platelets; Body Weight; Cell Separation; Female; Hemorrhage; Humans; Hydroxyurea; Platelet Count; Quinazolines; Thrombocythemia, Essential; Thrombocytosis

2014
Drug interaction studies reveal that simotinib upregulates intestinal absorption by increasing the paracellular permeability of intestinal epithelial cells.
    Drug metabolism and pharmacokinetics, 2014, Volume: 29, Issue:4

    Topics: Acyclovir; Anti-Infective Agents; Body Weight; Caco-2 Cells; Cefaclor; Dose-Response Relationship, Drug; Drug Interactions; Humans; Intestinal Absorption; Intestinal Mucosa; Microfilament Proteins; Permeability; Quinazolines; Spiro Compounds; Up-Regulation; Valacyclovir; Valine

2014
Neuronal CCL2 is upregulated during hepatic encephalopathy and contributes to microglia activation and neurological decline.
    Journal of neuroinflammation, 2014, Jul-10, Volume: 11

    Topics: Animals; Azoxymethane; Benzamides; Body Temperature; Body Weight; Carcinogens; Chemokine CCL2; Disease Models, Animal; Enzyme Inhibitors; Glycine; Hepatic Encephalopathy; Liver; Male; Mice; Mice, Inbred C57BL; Microglia; Nervous System Diseases; Quinazolines; Signal Transduction; Time Factors; Up-Regulation

2014
Assay of lapatinib in murine models of cigarette smoke carcinogenesis.
    Carcinogenesis, 2014, Volume: 35, Issue:10

    Topics: Animals; Antineoplastic Agents; Body Weight; Disease Models, Animal; DNA Adducts; DNA Damage; Erythrocytes; Gene Expression Regulation; Lapatinib; Lung; Lung Neoplasms; Mice; MicroRNAs; Protein Kinase Inhibitors; Quinazolines; Tobacco Smoke Pollution; Toxicity Tests, Subchronic

2014
The DPP-IV inhibitor linagliptin and GLP-1 induce synergistic effects on body weight loss and appetite suppression in the diet-induced obese rat.
    European journal of pharmacology, 2014, Oct-15, Volume: 741

    Topics: Animals; Appetite Depressants; Body Weight; Diet, High-Fat; Dietary Sucrose; Dipeptidyl-Peptidase IV Inhibitors; Drug Synergism; Drug Therapy, Combination; Glucagon-Like Peptide 1; Linagliptin; Male; Obesity; Purines; Quinazolines; Rats; Rats, Sprague-Dawley; Weight Loss

2014
Characterization of Batracylin-induced Renal and Bladder Toxicity in Rats.
    Toxicologic pathology, 2015, Volume: 43, Issue:4

    Topics: Animals; Biomarkers, Tumor; Body Weight; Female; Glycosuria; Histones; Kidney Neoplasms; Male; Mesna; Phosphoproteins; Quinazolines; Random Allocation; Rats; Urinary Bladder Neoplasms

2015
Epidermal growth factor receptor inhibition with erlotinib partially prevents cisplatin-induced nephrotoxicity in rats.
    PloS one, 2014, Volume: 9, Issue:11

    Topics: Animals; Antineoplastic Agents; Apoptosis; Body Weight; Cell Line; Chemical and Drug Induced Liver Injury; Cisplatin; ErbB Receptors; Erlotinib Hydrochloride; Humans; Kidney Tubules, Proximal; Liver; Macrophages; Male; Phosphorylation; Protein Kinase Inhibitors; Quinazolines; Rats; Rats, Sprague-Dawley; RNA, Messenger

2014
EGFR inhibition protects cardiac damage and remodeling through attenuating oxidative stress in STZ-induced diabetic mouse model.
    Journal of molecular and cellular cardiology, 2015, Volume: 82

    Topics: Animals; Apoptosis; Blood Glucose; Body Weight; Cell Line; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Disease Models, Animal; ErbB Receptors; Fibrosis; Male; Mice; Myocardium; Oxidative Stress; Proto-Oncogene Proteins c-akt; Quinazolines; Reactive Oxygen Species; Signal Transduction; Tyrphostins; Ventricular Remodeling

2015
Contribution of protease-activated receptor 1 in status epilepticus-induced epileptogenesis.
    Neurobiology of disease, 2015, Volume: 78

    Topics: Animals; Body Weight; CA1 Region, Hippocampal; Male; Pyrroles; Quinazolines; Rats; Rats, Wistar; Receptor, PAR-1; Status Epilepticus; Thrombin

2015
The effect of the DcpS inhibitor D156844 on the protective action of follistatin in mice with spinal muscular atrophy.
    Neuromuscular disorders : NMD, 2015, Volume: 25, Issue:9

    Topics: Animals; Body Weight; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; Endoribonucleases; Female; Follistatin; Kaplan-Meier Estimate; Male; Mice; Mice, Transgenic; Motor Activity; Muscular Atrophy, Spinal; Quinazolines; Recombinant Proteins; Survival of Motor Neuron 1 Protein; Survival of Motor Neuron 2 Protein

2015
Population pharmacokinetic and exposure simulation analysis for cediranib (AZD2171) in pooled Phase I/II studies in patients with cancer.
    British journal of clinical pharmacology, 2017, Volume: 83, Issue:8

    Topics: Administration, Oral; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Body Weight; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Drug Administration Schedule; Female; Glucuronosyltransferase; Humans; Inhibitory Concentration 50; Male; Middle Aged; Models, Biological; Neoplasms; Polypharmacy; Protein Kinase Inhibitors; Quinazolines; Rifampin; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2; Vascular Endothelial Growth Factor Receptor-3; Young Adult

2017
Dissociation of antihyperglycaemic and adverse effects of partial perioxisome proliferator-activated receptor (PPAR-gamma) agonist balaglitazone.
    European journal of pharmacology, 2008, Oct-31, Volume: 596, Issue:1-3

    Topics: Adipogenesis; Adipose Tissue; Animals; Blood Volume; Body Weight; Drinking; Eating; Heart; Humans; Hypoglycemic Agents; Male; Mice; Organ Size; PPAR gamma; Quinazolines; Rats; Rosiglitazone; Thiazolidinediones

2008
Intragastric administration of evodiamine suppresses NPY and AgRP gene expression in the hypothalamus and decreases food intake in rats.
    Brain research, 2009, Jan-09, Volume: 1247

    Topics: Agouti-Related Protein; Animals; Appetite Regulation; Arcuate Nucleus of Hypothalamus; Body Weight; Dose-Response Relationship, Drug; Down-Regulation; Feeding Behavior; Gene Expression Regulation; Hypothalamus; Leptin; Male; Neuropeptide Y; Plant Extracts; Quinazolines; Rats; Rats, Sprague-Dawley; RNA, Messenger

2009
F84, a quinazoline derivative, exhibits high potent antitumor activity against human gynecologic malignancies.
    Investigational new drugs, 2010, Volume: 28, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Body Weight; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Synergism; ErbB Receptors; Female; Genital Neoplasms, Female; Humans; Mice; Mitogen-Activated Protein Kinases; Organ Size; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinazolines; Xenograft Model Antitumor Assays

2010
Endurance exercise training preserves cardiac function in rats receiving doxorubicin and the HER-2 inhibitor GW2974.
    Cancer chemotherapy and pharmacology, 2009, Volume: 64, Issue:6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Body Weight; Caspase 3; Caspase 8; Doxorubicin; Exercise Therapy; Female; Heart; Heart Ventricles; Lipid Peroxidation; Malondialdehyde; Oxidative Stress; Quinazolines; Rats; Rats, Sprague-Dawley; Ventricular Dysfunction, Left; Ventricular Pressure

2009
Antitumor actions of imidazolyl-(4-oxoquinazolin-3(4H)-yl)-acetamides against Ehrlich Ascites Carcinoma.
    Archives of pharmacal research, 2009, Volume: 32, Issue:3

    Topics: Acetamides; Animals; Antineoplastic Agents; Body Weight; Carcinoma, Ehrlich Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Female; Hematologic Tests; Imidazoles; Lethal Dose 50; Mice; Quinazolines; Vincristine; Xenograft Model Antitumor Assays

2009
Effects of an epidermal growth factor receptor inhibitor on arsenic associated toxicity in the rat bladder epithelium.
    Toxicology letters, 2009, Jun-01, Volume: 187, Issue:2

    Topics: Animals; Arsenites; Body Weight; Cacodylic Acid; Cell Growth Processes; Cell Line; Cell Survival; Drinking; Eating; ErbB Receptors; Female; Gefitinib; Histocytochemistry; Quinazolines; Random Allocation; Rats; Rats, Inbred F344; Urinary Bladder

2009
A comparison of glycemic control, water retention, and musculoskeletal effects of balaglitazone and pioglitazone in diet-induced obese rats.
    European journal of pharmacology, 2009, Aug-15, Volume: 616, Issue:1-3

    Topics: Adipogenesis; Animals; Biomarkers; Blood Glucose; Body Weight; Bone and Bones; Bone Resorption; Diet; Glucose Tolerance Test; Hypoglycemic Agents; Lipid Metabolism; Magnetic Resonance Imaging; Male; Muscles; Obesity; Osteogenesis; Pioglitazone; PPAR alpha; Quinazolines; Rats; Thiazolidinediones; Water

2009
The intestinotrophic peptide, GLP-2, counteracts the gastrointestinal atrophy in mice induced by the epidermal growth factor receptor inhibitor, erlotinib, and cisplatin.
    Digestive diseases and sciences, 2010, Volume: 55, Issue:10

    Topics: Animals; Antineoplastic Agents; Atrophy; Body Weight; Cisplatin; Dose-Response Relationship, Drug; Drug Interactions; Erlotinib Hydrochloride; Female; Gastroenteritis; Gastrointestinal Tract; Glucagon-Like Peptide 2; Mice; Mice, Inbred Strains; Protein Kinase Inhibitors; Quinazolines

2010
Interstitial infusion of erlotinib in the rodent brain.
    Journal of experimental therapeutics & oncology, 2009, Volume: 8, Issue:2

    Topics: Animals; Body Weight; Brain; Brain Neoplasms; Dose-Response Relationship, Drug; ErbB Receptors; Erlotinib Hydrochloride; Glioma; Microinjections; Neostriatum; Quinazolines; Rats; Rats, Nude

2009
Reversal of isoprenaline-induced cardiac remodeling by rutaecarpine via stimulation of calcitonin gene-related peptide production.
    Canadian journal of physiology and pharmacology, 2010, Volume: 88, Issue:10

    Topics: Animals; Apoptosis; Body Weight; Calcitonin Gene-Related Peptide; Echocardiography; Ganglia, Spinal; Heart Ventricles; In Situ Nick-End Labeling; Indole Alkaloids; Isoproterenol; Male; Myocytes, Cardiac; Organ Size; Quinazolines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Ventricular Remodeling

2010
Whole-body biodistribution kinetics, metabolism, and radiation dosimetry estimates of 18F-PEG6-IPQA in nonhuman primates.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2011, Volume: 52, Issue:6

    Topics: Aging; Animals; Body Weight; Female; Gallbladder; Image Processing, Computer-Assisted; Macaca mulatta; Male; Positron-Emission Tomography; Quinazolines; Radiometry; Radiopharmaceuticals; Tissue Distribution; Tomography, Emission-Computed; Whole-Body Counting

2011
Angiotensin-(1-7) inhibits epidermal growth factor receptor transactivation via a Mas receptor-dependent pathway.
    British journal of pharmacology, 2012, Volume: 165, Issue:5

    Topics: Angiotensin I; Angiotensin II; Animals; Body Weight; Diabetes Mellitus; ErbB Receptors; Glucose; Hyperglycemia; Male; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Quinazolines; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Signal Transduction; src-Family Kinases; Transcriptional Activation; Tyrphostins

2012
Behavior and anti-glioma effect of lapatinib-incorporated lipoprotein-like nanoparticles.
    Nanotechnology, 2012, Nov-02, Volume: 23, Issue:43

    Topics: Animals; Antineoplastic Agents; Body Weight; Cell Line, Tumor; Coumarins; Endocytosis; Fluorescent Antibody Technique; Glioma; Humans; Imaging, Three-Dimensional; In Situ Nick-End Labeling; Lapatinib; Lipoproteins; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Confocal; Nanoparticles; Osteonectin; Quinazolines; Receptor, ErbB-2; Subcellular Fractions; Xenograft Model Antitumor Assays

2012
In vivo anti-tumour activity of novel Quinazoline derivatives.
    European review for medical and pharmacological sciences, 2012, Volume: 16, Issue:13

    Topics: Animals; Antineoplastic Agents; Body Weight; Cell Line, Tumor; Female; Mice; Neoplasms, Experimental; Quinazolines

2012
Treatment of post-bone marrow transplant acute graft-versus-host disease with a rationally designed JAK3 inhibitor.
    Leukemia & lymphoma, 2002, Volume: 43, Issue:7

    Topics: Acute Disease; Animals; Body Weight; Bone Marrow Transplantation; Drug Design; Drug Evaluation, Preclinical; Enzyme Inhibitors; Graft vs Host Disease; Histocompatibility; Janus Kinase 3; Mice; Mice, Inbred BALB C; Mice, Knockout; Protein-Tyrosine Kinases; Quinazolines; Survival Analysis; Transplantation, Homologous

2002
The combi-targeting concept: dissection of the binary mechanism of action of the combi-triazene SMA41 in vitro and antitumor activity in vivo.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:3

    Topics: Animals; Antineoplastic Agents; Blotting, Western; Body Weight; Cell Cycle; Cell Line, Tumor; Chromatography, High Pressure Liquid; Comet Assay; DNA Damage; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Delivery Systems; Epidermal Growth Factor; Flow Cytometry; Humans; Mice; Mice, SCID; Mitogen-Activated Protein Kinases; Neoplasm Transplantation; Neoplasms; Quinazolines; Signal Transduction

2004
[Effect of epidermal growth factor receptor-selective tyrosine kinase inhibitor gefitinib on nasopharyngeal carcinoma xenografts].
    Ai zheng = Aizheng = Chinese journal of cancer, 2004, Volume: 23, Issue:11 Suppl

    Topics: Animals; Antineoplastic Agents; Body Weight; Cell Line, Tumor; Cisplatin; Drug Synergism; ErbB Receptors; Female; Gefitinib; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nasopharyngeal Neoplasms; Neoplasm Transplantation; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Quinazolines; Random Allocation

2004
The role of tyrosine kinase-mediated pathways in diabetes-induced alterations in responsiveness of rat carotid artery.
    Autonomic & autacoid pharmacology, 2005, Volume: 25, Issue:2

    Topics: Animals; Benzothiazoles; Body Weight; Carotid Arteries; Diabetes Mellitus, Experimental; Enzyme Inhibitors; ErbB Receptors; Female; Genes, erbB-1; Genes, erbB-2; Genistein; In Vitro Techniques; Protein-Tyrosine Kinases; Quinazolines; Rats; Rats, Wistar; Signal Transduction; Tyrphostins; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2005
Antitumor effect of Gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, combined with cytotoxic agent on murine hepatocellular carcinoma.
    World journal of gastroenterology, 2005, Mar-07, Volume: 11, Issue:9

    Topics: Animals; Antineoplastic Agents; Blood Cell Count; Body Weight; Carcinoma, Hepatocellular; Cisplatin; Cytotoxins; Drug Therapy, Combination; ErbB Receptors; Female; Gefitinib; Liver Neoplasms; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Organ Size; Quinazolines; Spleen; Thymus Gland

2005
Chemopreventive and therapeutic efficacy of orally active tyrosine kinase inhibitors in a transgenic mouse model of gallbladder carcinoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Aug-01, Volume: 11, Issue:15

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Blotting, Western; Body Weight; Carcinoma; Cell Line, Tumor; Disease Models, Animal; Enzyme Inhibitors; ErbB Receptors; Gallbladder; Gallbladder Neoplasms; Gefitinib; Humans; In Situ Nick-End Labeling; MAP Kinase Signaling System; Mice; Mice, Transgenic; Microscopy, Fluorescence; Neoplasms, Experimental; Phosphorylation; Protein-Tyrosine Kinases; Quinazolines; Receptor, ErbB-2; Tolonium Chloride

2005
The effects of ZD6474, an inhibitor of VEGF signaling, on cutaneous wound healing in mice.
    The Journal of surgical research, 2005, Volume: 129, Issue:2

    Topics: Animals; Body Weight; Dermatologic Surgical Procedures; Female; Mice; Mice, Inbred BALB C; Microcirculation; Neovascularization, Physiologic; Piperidines; Quinazolines; Signal Transduction; Skin; Stress, Mechanical; Vascular Endothelial Growth Factor Receptor-2; Wound Healing; Wounds and Injuries

2005
The antihyperlipidemic activities of 4(3H) quinazolinone and two halogenated derivatives in rats.
    Lipids in health and disease, 2005, Oct-04, Volume: 4

    Topics: Animals; Bezafibrate; Blood Glucose; Body Weight; Cholesterol, Dietary; Diabetes Mellitus, Experimental; Hypercholesterolemia; Hypolipidemic Agents; Lipids; Male; Malondialdehyde; Quinazolines; Quinazolinones; Rats

2005
Reduction of voluntary ethanol consumption in alcohol-preferring Alko alcohol (AA) rats by desoxypeganine and galanthamine.
    European journal of pharmacology, 2005, Oct-17, Volume: 522, Issue:1-3

    Topics: Alcohol Drinking; Analysis of Variance; Animals; Body Weight; Dose-Response Relationship, Drug; Eating; Ethanol; Female; Galantamine; Quinazolines; Rats; Time Factors

2005
Immunosuppressive effects of rutaecarpine in female BALB/c mice.
    Toxicology letters, 2006, Jul-01, Volume: 164, Issue:2

    Topics: Alkaloids; Animals; Antibody Formation; Body Weight; Cell Cycle; Dose-Response Relationship, Drug; Female; Immunosuppression Therapy; Indole Alkaloids; Interleukin-2; Mice; Mice, Inbred BALB C; Organ Size; Quinazolines; Spleen; Vasodilator Agents

2006
Improvement by solid dispersion of the bioavailability of KRN633, a selective inhibitor of VEGF receptor-2 tyrosine kinase, and identification of its potential therapeutic window.
    Molecular cancer therapeutics, 2006, Volume: 5, Issue:1

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Biological Availability; Blood Vessels; Body Weight; Crystallization; Drug Compounding; Drug Stability; Humans; Male; Mice; Mice, Nude; Neovascularization, Pathologic; Phenylurea Compounds; Quinazolines; Rats; Rats, Sprague-Dawley; Solubility; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays

2006
[Inhibitory effects of iressa on hepatocellular carcinoma Hep-3B and HepG2 cell xenografts in nude mice].
    Ai zheng = Aizheng = Chinese journal of cancer, 2006, Volume: 25, Issue:4

    Topics: Animals; Antineoplastic Agents; Body Weight; Cell Line, Tumor; Dose-Response Relationship, Drug; Female; Gefitinib; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Quinazolines; Random Allocation; Xenograft Model Antitumor Assays

2006
The intestinotrophic peptide, glp-2, counteracts intestinal atrophy in mice induced by the epidermal growth factor receptor inhibitor, gefitinib.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Sep-01, Volume: 13, Issue:17

    Topics: Animals; Antineoplastic Agents; Atrophy; Body Weight; ErbB Receptors; Female; Gefitinib; Glucagon-Like Peptide 2; Intestines; Mice; Mice, Inbred C57BL; Organ Size; Quinazolines

2007
Inhibition by erlotinib of primary lung adenocarcinoma at an early stage in male mice.
    Cancer chemotherapy and pharmacology, 2008, Volume: 62, Issue:4

    Topics: Adenoma; Animals; Antineoplastic Agents; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; ErbB Receptors; Erlotinib Hydrochloride; Female; Injections, Intraperitoneal; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Mutation; Protein Kinase Inhibitors; Proto-Oncogene Proteins p21(ras); Quinazolines; Sex Factors

2008
Clonidine and prazosin effects in hypernoradrenergic vasodilator-treated and beta-blocker-treated patients.
    Clinical pharmacology and therapeutics, 1981, Volume: 30, Issue:3

    Topics: Adrenergic beta-Antagonists; Blood Pressure; Body Weight; Clonidine; Diastole; Diuretics; Female; Humans; Hypertension; Male; Middle Aged; Minoxidil; Norepinephrine; Posture; Prazosin; Propranolol; Quinazolines; Renin; Systole

1981
Open assessment of the effect of prazosin on plasma lipids.
    Journal of cardiovascular pharmacology, 1982, Volume: 4 Suppl 2

    Topics: Adult; Blood Pressure; Body Weight; Cholesterol; Cholesterol, HDL; Female; Heart Rate; Humans; Hypertension; Lipoproteins, HDL; Male; Middle Aged; Prazosin; Quinazolines; Triglycerides

1982
Effects of tiodazosin, a new antihypertensive, hemodynamics and clinical variables.
    Clinical pharmacology and therapeutics, 1983, Volume: 34, Issue:3

    Topics: Adult; Blood Chemical Analysis; Blood Pressure; Body Weight; Cardiac Output; Drug Evaluation; Electrocardiography; Female; Half-Life; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Prazosin; Quinazolines

1983
Anticoccidial drugs: growth and performance depressing effects in young chickens.
    Poultry science, 1982, Volume: 61, Issue:4

    Topics: Adenine; Animal Feed; Animals; Body Weight; Chickens; Coccidiostats; Growth; Lasalocid; Male; Monensin; Nicarbazin; Piperidines; Quinazolines; Quinazolinones

1982
[The development of weaned piglets experimentally infected with Isospora suis as a model for the effect of lasalocid and halofuginone on coccidia (author's transl)].
    Zentralblatt fur Bakteriologie. 1. Abt. Originale. A: Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie, 1981, Volume: 248, Issue:4

    Topics: Animals; Body Weight; Coccidiosis; Feces; Isospora; Lasalocid; Piperidines; Quinazolines; Quinazolinones; Swine; Weaning

1981
Effect of prazosin on renal function in chronic congestive cardiac failure.
    The Medical journal of Australia, 1981, Sep-19, Volume: 2, Issue:6

    Topics: Adult; Aged; Body Weight; Creatinine; Gout; Heart Failure; Humans; Kidney; Male; Middle Aged; Prazosin; Quinazolines; Tachycardia; Urea; Vasodilator Agents

1981
The effects of halofuginone and salinomycin, alone and in combination, on live performance and skin characteristics of female broilers: influence of a high-proline diet supplemented with ascorbic acid and zinc.
    Poultry science, 1995, Volume: 74, Issue:2

    Topics: Animals; Ascorbic Acid; Body Weight; Chickens; Coccidiostats; Female; Food, Fortified; Piperidines; Proline; Pyrans; Quinazolines; Quinazolinones; Skin; Skin Physiological Phenomena; Tensile Strength; Zinc

1995
The effects of halofuginone and salinomycin, alone and in combination, on live performance and skin characteristics of broilers.
    Poultry science, 1995, Volume: 74, Issue:2

    Topics: Animals; Body Weight; Chickens; Coccidiostats; Female; Food, Fortified; Male; Piperidines; Pyrans; Quinazolines; Quinazolinones; Sex Factors; Skin; Skin Physiological Phenomena; Tensile Strength

1995
The effects of shuttle programs upon the growth of broilers and the development of immunity to eimeria species.
    Poultry science, 1993, Volume: 72, Issue:4

    Topics: Animals; Body Weight; Chickens; Coccidiosis; Coccidiostats; Diet; Eimeria; Feces; Immunity; Male; Nicarbazin; Parasite Egg Count; Piperidines; Poultry Diseases; Quinazolines; Quinazolinones; Robenidine

1993
Enhanced antitumor activity for the thymidylate synthase inhibitor 1843U89 through decreased host toxicity with oral folic acid.
    Cancer research, 1995, Dec-15, Volume: 55, Issue:24

    Topics: Animals; Body Weight; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Folic Acid; Humans; Indoles; Intestinal Diseases; Isoindoles; Leucovorin; Mice; Neoplasms, Experimental; Osteosarcoma; Quinazolines; Thymidylate Synthase; Tumor Cells, Cultured

1995
Mitigating the effects of halofuginone on skin strength by feeding L-proline to broiler chickens.
    Poultry science, 1995, Volume: 74, Issue:10

    Topics: Animals; Body Weight; Chickens; Coccidiostats; Collagen; Female; Food, Fortified; Male; Piperidines; Proline; Quinazolines; Quinazolinones; Skin; Skin Physiological Phenomena; Tensile Strength

1995
Thromboxane inhibition potentiates antihypertensive effects of alpha 1 adrenoceptor antagonists in the rat.
    Prostaglandins, leukotrienes, and essential fatty acids, 1997, Volume: 56, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Body Weight; Cells, Cultured; Drug Synergism; Eicosanoids; Ethanolamines; Kidney; Methacrylates; Muscle, Smooth, Vascular; Prazosin; Quinazolines; Rats; Rats, Inbred SHR; Sodium; Thromboxane-A Synthase; Thromboxanes

1997
Cataract development induced by repeated oral dosing with FK506 (tacrolimus) in adult rats.
    Toxicology, 1997, Dec-05, Volume: 123, Issue:3

    Topics: Administration, Oral; Aldehyde Reductase; Animals; Blood Glucose; Body Weight; Cataract; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Glucose Tolerance Test; Glutathione; Immunosuppressive Agents; Insulin; Lens, Crystalline; Male; Quinazolines; Rats; Sodium-Potassium-Exchanging ATPase; Sorbitol; Tacrolimus

1997
Regulation of angiotensin II receptor expression by nitric oxide in rat adrenal gland.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 32, Issue:3

    Topics: Adrenal Glands; Adrenergic alpha-Antagonists; Aldosterone; Animals; Blotting, Northern; Body Weight; DNA, Complementary; Enzyme Inhibitors; Gene Expression Regulation; Hemodynamics; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptidyl-Dipeptidase A; Quinazolines; Rats; Rats, Wistar; Receptors, Angiotensin; Renin; RNA, Messenger

1998
Inhibition of epidermal growth factor receptor-associated tyrosine phosphorylation in human carcinomas with CP-358,774: dynamics of receptor inhibition in situ and antitumor effects in athymic mice.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2

    Topics: Animals; Antineoplastic Agents; Body Weight; Cell Division; Cisplatin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; ErbB Receptors; Erlotinib Hydrochloride; Female; Head and Neck Neoplasms; Humans; Mice; Mice, Nude; Phosphorylation; Phosphotyrosine; Polypharmacy; Quinazolines; Time Factors; Transplantation, Heterologous; Tumor Cells, Cultured; Tyrosine

1999
Leucovorin rescue from raltitrexed (tomudex)-induced antiproliferative effects: in vitro cell line and in vivo mouse studies.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:9

    Topics: Animals; Antimetabolites, Antineoplastic; Body Weight; Cell Division; Cell Line; Drug Interactions; Humans; Intestinal Mucosa; Intestine, Small; Leucovorin; Leukemia L1210; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Neutropenia; Polyglutamic Acid; Quinazolines; Thiophenes; Thrombocytopenia

2000
The effects of zenarestat, an aldose reductase inhibitor, on peripheral neuropathy in Zucker diabetic fatty rats.
    Metabolism: clinical and experimental, 2000, Volume: 49, Issue:11

    Topics: Aldehyde Reductase; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Disease Models, Animal; Enzyme Inhibitors; Male; Quinazolines; Rats; Rats, Zucker

2000
Efficacy of cytotoxic agents against human tumor xenografts is markedly enhanced by coadministration of ZD1839 (Iressa), an inhibitor of EGFR tyrosine kinase.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:12

    Topics: Aminopterin; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Carboplatin; Cell Division; Cisplatin; Docetaxel; Dose-Response Relationship, Drug; ErbB Receptors; Female; Gefitinib; Humans; Immunohistochemistry; Lung Neoplasms; Male; Maximum Tolerated Dose; Mice; Mice, Nude; Neoplasm Transplantation; Paclitaxel; Prostatic Neoplasms; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; Taxoids; Time Factors; Tumor Cells, Cultured; Vinblastine; Vinorelbine; Vulvar Neoplasms

2000
Capsaicin-like anti-obese activities of evodiamine from fruits of Evodia rutaecarpa, a vanilloid receptor agonist.
    Planta medica, 2001, Volume: 67, Issue:7

    Topics: Adipose Tissue; Animals; Anti-Obesity Agents; Body Temperature; Body Weight; Capsaicin; Cholesterol; Fatty Acids, Nonesterified; Fruit; Japan; Lipid Metabolism; Lipolysis; Liver; Male; Medicine, East Asian Traditional; Mice; Mice, Inbred C3H; Obesity; Phytotherapy; Plant Extracts; Plants, Medicinal; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Drug; Rutaceae; Triglycerides

2001
[Prazosin in the combined treatment of moderate to severe hypertension].
    Schweizerische medizinische Wochenschrift, 1979, Jun-30, Volume: 109, Issue:26

    Topics: Adrenergic beta-Antagonists; Body Weight; Diuretics; Dizziness; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Prazosin; Pulse; Quinazolines

1979
Chronic toxicity studies of a hypoglycemic compound: centperalone in rats & rhesus monkeys.
    Indian journal of experimental biology, 1979, Volume: 17, Issue:12

    Topics: Animals; Blood Chemical Analysis; Body Weight; Female; Haplorhini; Hypoglycemic Agents; Macaca mulatta; Male; Piperazines; Quinazolines; Quinazolinones; Rats

1979
Toxicological investigation of 2,3-dihydro-9H-isoxazolo[3,2-b]quinazolin-9-one (W-2429). Acute and subacute toxicity in mice, rats and dogs.
    Arzneimittel-Forschung, 1977, Volume: 27, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Cell Count; Blood Chemical Analysis; Body Weight; Dogs; Female; Isoxazoles; Lethal Dose 50; Male; Mice; Organ Size; Oxazoles; Quinazolines; Rats; Spermatogenesis; Time Factors

1977
Efficacy of Stenorol (halofuginone). I. Against recent field isolates of six species of chicken coccidia.
    Poultry science, 1979, Volume: 58, Issue:6

    Topics: Animals; Body Weight; Chickens; Coccidiosis; Coccidiostats; Drug Resistance; Eimeria; Feeding Behavior; Piperidines; Poultry Diseases; Quinazolines; Quinazolinones

1979
Efficacy of Stenorol (halofuginone). II. Plus roxarsone or bacitracin MD against selected strains of chicken Eimeria.
    Poultry science, 1979, Volume: 58, Issue:6

    Topics: Animals; Arsenicals; Bacitracin; Body Weight; Chickens; Coccidiosis; Coccidiostats; Drug Combinations; Eimeria; Feeding Behavior; Piperidines; Poultry Diseases; Quinazolines; Quinazolinones; Roxarsone; Salicylates

1979
Naphthalene-induced cataract in the rat. II. Contrasting effects of two aldose reductase inhibitors on glutathione and glutathione redox enzymes.
    Ophthalmic research, 1991, Volume: 23, Issue:5

    Topics: Aldehyde Reductase; Animals; Body Weight; Cataract; Disease Models, Animal; Female; Fluorenes; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Hydantoins; Lens, Crystalline; Naphthalenes; Organ Size; Quinazolines; Random Allocation; Rats; Rats, Inbred BN

1991
Comparison of different anticoccidials on processing characteristics and parts yield of broiler chickens.
    Poultry science, 1991, Volume: 70, Issue:6

    Topics: Animals; Body Weight; Chickens; Coccidiostats; Eating; Female; Male; Monensin; Muscle Development; Muscles; Piperidines; Pyrans; Quinazolines; Quinazolinones; Random Allocation

1991
Chemotherapy of East Coast fever. Treatment of infections induced by isolates of Theileria parva with halofuginone.
    Acta tropica, 1986, Volume: 43, Issue:2

    Topics: Animals; Antiprotozoal Agents; Body Weight; Carrier State; Cattle; Leukocyte Count; Lymph Nodes; Male; Piperidines; Quinazolines; Quinazolinones; Theileriasis; Ticks

1986
Teratogenicity of the antiallergic Sm 857 SE in rats versus rabbits.
    Teratology, 1988, Volume: 38, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Female; Fetus; Histamine H1 Antagonists; Pregnancy; Quinazolines; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Teratogens

1988
Anticoccidial evaluation of halofuginone, lasalocid, maduramicin, monensin and salinomycin.
    Veterinary parasitology, 1988, Volume: 28, Issue:1-2

    Topics: Animals; Anti-Bacterial Agents; Body Weight; Chickens; Coccidiosis; Coccidiostats; Eimeria; Female; Ionophores; Lactones; Lasalocid; Male; Monensin; Piperidines; Poultry Diseases; Pyrans; Quinazolines; Quinazolinones

1988
Efficacy of halofuginone as a coccidiostat for turkeys.
    Poultry science, 1987, Volume: 66, Issue:10

    Topics: Animal Nutritional Physiological Phenomena; Animals; Body Weight; Coccidiosis; Coccidiostats; Male; Piperidines; Poultry Diseases; Quinazolines; Quinazolinones; Turkeys

1987
Response of broiler chickens to addition of bacitracin methylene disalicylate and roxarsone to diets containing halofuginone.
    Poultry science, 1987, Volume: 66, Issue:10

    Topics: Animal Feed; Animals; Arsenicals; Bacitracin; Body Weight; Chickens; Coccidiosis; Coccidiostats; Female; Food Additives; Male; Piperidines; Poultry Diseases; Quinazolines; Quinazolinones; Roxarsone

1987
[Tolerance of halofuginone (Stenorol) by geese (Anser anser f. dom.), flight ducks (Cairina moschata f. dom.) and Peking ducks (Anas platyrhynchos f. dom.)].
    DTW. Deutsche tierarztliche Wochenschrift, 1986, Jan-07, Volume: 93, Issue:1

    Topics: Animals; Body Weight; Coccidiostats; Ducks; Eating; Geese; Piperidines; Quinazolines; Quinazolinones

1986
Halofuginone: laboratory titration of anticoccidial activity in young turkeys.
    Poultry science, 1986, Volume: 65, Issue:2

    Topics: Animals; Body Weight; Coccidiosis; Coccidiostats; Feeding Behavior; Piperidines; Poultry Diseases; Quinazolines; Quinazolinones; Turkeys

1986
The use of bambermycins (Flavomycin) and halofuginone (Stenorol) in diets for growing turkeys.
    Poultry science, 1985, Volume: 64, Issue:7

    Topics: Animals; Anti-Bacterial Agents; Arkansas; Bambermycins; Body Weight; Coccidiostats; Colorado; Female; Food Additives; Male; Minnesota; Piperidines; Quinazolines; Quinazolinones; Sex Factors; Turkeys

1985
[Effects of new antihypertensive agent, 2-[4-(n-butyryl)-homopiperazine-1-ul]-4-amino-6, 7-dimethoxy-quinazoline (E-643), on blood pressure, urinary sodium excretion and urinary norepinephrine excretion rate in stroke-prone, spontaneously hypertensive rat
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1985, Volume: 60, Issue:4

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Catecholamines; Cerebrovascular Disorders; Eating; Heart Rate; Humans; Hypertension; Kidney; Male; Natriuresis; Norepinephrine; Potassium; Quinazolines; Rats; Rats, Inbred SHR

1985
[Effect of HPS on leucocytozoon and coccidial infection in chickens].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1985, Volume: 86, Issue:3

    Topics: Animals; Antibodies; Antigens, Protozoan; Antiprotozoal Agents; Body Weight; Chickens; Coccidiosis; Coccidiostats; Feces; Female; Male; Polystyrenes; Poultry Diseases; Protozoan Infections; Protozoan Infections, Animal; Quinazolines

1985
[Pharmacological studies on quinazoline-2, 4-dione derivaties, H-27 and H-88: (1) anti-inflammatory, analgesic and antipyretic activities].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1974, Volume: 70, Issue:5

    Topics: Adrenalectomy; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Body Temperature; Body Weight; Capillary Permeability; Cordotomy; Drug Evaluation, Preclinical; Edema; Erythema; Female; Granulation Tissue; Hemolysis; Lethal Dose 50; Male; Mice; Quinazolines; Rabbits; Rats

1974
Pharmacology of a new hypnotic drug: HQ-355.
    Japanese journal of pharmacology, 1972, Volume: 22, Issue:3

    Topics: Animals; Anticonvulsants; Body Weight; Glutethimide; Hypnotics and Sedatives; Lethal Dose 50; Male; Methaqualone; Mice; Quinazolines; Quinazolinones; Rabbits; Sleep; Time Factors

1972
Efficacy of metolazone in patients with renal edema.
    Clinical nephrology, 1974, Volume: 2, Issue:4

    Topics: Adolescent; Adult; Aged; Body Weight; Diuresis; Diuretics; Drug Evaluation; Edema; Female; Glomerular Filtration Rate; Humans; Male; Middle Aged; Nephrosis; Potassium; Quinazolines; Sulfonamides

1974
Toxicologic studies of the 2,4-diamino-quinazoline antifolate, methasquin (NSC-122870).
    Cancer chemotherapy reports, 1971, Volume: 55, Issue:1

    Topics: Administration, Oral; Animals; Blood Cells; Body Weight; Bone Marrow; Bone Marrow Cells; Dogs; Female; Folic Acid Antagonists; Haplorhini; Injections, Intraperitoneal; Injections, Intravenous; Intestines; Macaca; Male; Methotrexate; Mice; Quinazolines; Rats

1971
Antiarthritic effects of the antispermatogenic agent 2,3-dihydro-(1-naphthyl)-4-(1H)-quinazolinone (U-29,409).
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1971, Volume: 138, Issue:1

    Topics: Administration, Oral; Animals; Arthritis; Body Weight; Carrageenan; Cyclophosphamide; Dosage Forms; Drug Synergism; Edema; Encephalomyelitis, Autoimmune, Experimental; Female; Ketones; Leukocytes; Male; Naphthalenes; Organ Size; Quinazolines; Rats; Rats, Inbred Strains; Sex Factors

1971
Clinical experience with metolazone in fifty-two African patients: synergy with frusemide.
    Postgraduate medical journal, 1971, Volume: 47, Issue:554

    Topics: Adult; Black People; Body Weight; Diuretics; Drug Synergism; Edema; Female; Furosemide; Humans; Ketones; Male; Middle Aged; Quinazolines; Sulfonamides

1971
Quinazoline antifolates: dosage schedules and toxicity.
    Cancer chemotherapy reports, 1971, Volume: 55, Issue:2

    Topics: Aminopterin; Animals; Antineoplastic Agents; Body Weight; Dosage Forms; Folic Acid Antagonists; Leucovorin; Leukemia, Experimental; Male; Methotrexate; Mice; Quinazolines

1971
Toxicologic investigations on moquizone (1-morpholinoacetyl-3-phenyl-2,3-dihydro-4(1H)-quinazolone).
    Toxicology and applied pharmacology, 1970, Volume: 16, Issue:3

    Topics: Animals; Blood Cell Count; Blood Cells; Blood Chemical Analysis; Body Weight; Central Nervous System; Cholagogues and Choleretics; Dogs; Female; Growth; Liver; Male; Mice; Morpholines; Motor Activity; Quinazolines; Rabbits; Rats; Species Specificity

1970