Page last updated: 2024-08-21

quinazolines and B-Cell Chronic Lymphocytic Leukemia

quinazolines has been researched along with B-Cell Chronic Lymphocytic Leukemia in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's6 (85.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Danilov, AV; Hamilton, BJ; Jones, JD; Rigby, WFC; Skopelja-Gardner, S1
Hallek, M; Hassenrück, F; Krause, G1
Andritsos, L; Awan, FT; Blachly, JS; Byrd, JC; Cannon, M; Chen, CS; El-Gamal, D; Jones, J; LaFollette, TD; Lapalombella, R; Lehman, A; Maddocks, K; Williams, E; Williams, K; Woyach, JA; Wu, CH; Zhang, X; Zhong, Y1
Banerji, V; Dielschneider, RF; Gibson, SB; Johnston, JB; Li, H; Marshall, AJ; Noh, E; Xiao, W; Yoon, JY1
Baumann, M; Frenzel, LP; Göckeritz, E; Hallek, M; Kerwien, S; Klein, C; Krause, G; Landwehr, T; Liu, N; Neumann, L; Vondey, V; Wendtner, CM; Wigger, M1
Bowen, D; Byrd, J; Call, T; Erlichman, C; Ghosh, A; Hanson, C; Jelinek, D; Kay, N; Laplant, B; Laumann, K; Shanafelt, T; Villalona-Calero, M; Wu, W; Zent, C1
Briones, J; Ferrer, B; Forné, I; Juarez, C; Martinez-Gallo, M; Martinez-Lostao, L; Rodriguez-Sanchez, JL; Sierra, J1

Reviews

1 review(s) available for quinazolines and B-Cell Chronic Lymphocytic Leukemia

ArticleYear
Copanlisib for treatment of B-cell malignancies: the development of a PI3K inhibitor with considerable differences to idelalisib.
    Drug design, development and therapy, 2018, Volume: 12

    Topics: Animals; Antineoplastic Agents; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Large B-Cell, Diffuse; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Purines; Pyrimidines; Quinazolines; Quinazolinones

2018

Trials

1 trial(s) available for quinazolines and B-Cell Chronic Lymphocytic Leukemia

ArticleYear
Phase II trials of single-agent anti-VEGF therapy for patients with chronic lymphocytic leukemia.
    Leukemia & lymphoma, 2010, Volume: 51, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Female; Humans; Indoles; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Pyrroles; Quinazolines; Sunitinib; Treatment Outcome; Vascular Endothelial Growth Factor A

2010

Other Studies

5 other study(ies) available for quinazolines and B-Cell Chronic Lymphocytic Leukemia

ArticleYear
Role for ZAP-70 Signaling in the Differential Effector Functions of Rituximab and Obinutuzumab (GA101) in Chronic Lymphocytic Leukemia B Cells.
    Journal of immunology (Baltimore, Md. : 1950), 2017, 08-15, Volume: 199, Issue:4

    Topics: Adenine; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antigens, CD20; Antineoplastic Agents; B-Lymphocytes; Cell Adhesion; Cell Adhesion Molecules; Gefitinib; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Monocytes; Piperidines; Pyrazoles; Pyrimidines; Quinazolines; Receptors, IgG; Rituximab; Signal Transduction; ZAP-70 Protein-Tyrosine Kinase

2017
PKC-β as a therapeutic target in CLL: PKC inhibitor AEB071 demonstrates preclinical activity in CLL.
    Blood, 2014, Aug-28, Volume: 124, Issue:9

    Topics: Apoptosis; beta Catenin; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Protein Kinase C beta; Protein Kinase Inhibitors; Pyrroles; Quinazolines; Receptors, Antigen, B-Cell; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Microenvironment; Wnt Signaling Pathway

2014
Gefitinib targets ZAP-70-expressing chronic lymphocytic leukemia cells and inhibits B-cell receptor signaling.
    Cell death & disease, 2014, Oct-02, Volume: 5

    Topics: Cell Survival; Gefitinib; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Protein Kinase Inhibitors; Quinazolines; Receptors, Antigen, B-Cell; Signal Transduction; Tumor Cells, Cultured; ZAP-70 Protein-Tyrosine Kinase

2014
Efficacy of phosphatidylinositol-3 kinase inhibitors with diverse isoform selectivity profiles for inhibiting the survival of chronic lymphocytic leukemia cells.
    International journal of cancer, 2015, Nov-01, Volume: 137, Issue:9

    Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Survival; Chemokine CXCL12; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Isoenzymes; Isoquinolines; Leukemia, Lymphocytic, Chronic, B-Cell; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Purines; Pyrimidines; Quinazolines; Quinazolinones; Rituximab; Signal Transduction

2015
Role of the STAT1 pathway in apoptosis induced by fludarabine and JAK kinase inhibitors in B-cell chronic lymphocytic leukemia.
    Leukemia & lymphoma, 2005, Volume: 46, Issue:3

    Topics: Aged; Aged, 80 and over; Apoptosis; Cell Survival; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Female; Flow Cytometry; Humans; Interferon-gamma; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Protein-Tyrosine Kinases; Quinazolines; Signal Transduction; STAT1 Transcription Factor; Time Factors; Trans-Activators; Tumor Cells, Cultured; Tyrphostins; Vidarabine

2005