Page last updated: 2024-08-21

quinazolines and Atherosclerosis

quinazolines has been researched along with Atherosclerosis in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (6.67)29.6817
2010's12 (80.00)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
Han, X; Jiang, X; Li, N; Li, Y; Liu, C; Luo, J; Si, S; Wang, X; Xu, Y; Zuo, X1
Fang, Z; Han, J; Lin, J; Lin, Y; Peng, W; Qin, Y; Shi, X; Xiao, F; Xu, X; Zhang, Y; Zhao, L1
Attwell, S; Campeau, E; Fontano, E; Gesner, EM; Hansen, HC; Kharenko, OA; McLure, KG; Stein, A; Suto, RK; Tsujikawa, L; Wagner, GS; Wasiak, S; White, A; Wong, NC; Young, PR1
Exner, M; Gmeiner, BM; Hermann, M; Jirovetz, L; Kapiotis, S; Laggner, H; Praschberger, M; Wanner, J1
Feng, T; He, X; Hong, B; Jiang, JD; Lai, F; Li, N; Li, Y; Liu, C; Liu, J; Liu, Q; Si, S; Wang, X; Wu, Y; Xu, Y; Zhang, M; Zhu, N1
Attwell, S; Azhar, S; Hansen, HC; Jahagirdar, R; Johansson, J; McLure, KG; Srivastava, RA; Tobin, J; Wagner, GS; Wong, NC; Wu, J; Young, PR; Yu, R; Zhang, H1
Jin, D; Sakonjo, H; Takai, S1
Banach, M; Mikhailidis, DP; Nikolic, D; Rizzo, M; Wong, NC1
Fu, YQ; He, M; Huang, QR; Liu, Y; Luo, D; Peng, WJ; Wu, YS; Yan, H; Yu, YR1
Gilham, D; Gordon, A; Halliday, C; Johansson, J; Kulikowski, E; McLure, K; Norek, K; Patel, RG; Sweeney, M; Tsujikawa, LM; Wasiak, S; Wong, NC; Young, P1
D'Acquisto, F; Mann, DA; Mann, J; Motterle, A; Souslova, V; Townsend, PA; van der Loos, CM; Ye, S1
Inazu, A1
Cheng, LC; Ching, LC; Kou, YR; Lee, TS; Pan, CC; Shyue, SK; Su, KH; Wei, J; Yu, YB1
Ali, N; Fujita, Y; Ishizawa, K; Izawa, Y; Kanematsu, Y; Ohnishi, H; Tamaki, T; Tsuchiya, K; Yoshizumi, M1

Reviews

3 review(s) available for quinazolines and Atherosclerosis

ArticleYear
An evaluation of RVX-208 for the treatment of atherosclerosis.
    Expert opinion on investigational drugs, 2015, Volume: 24, Issue:10

    Topics: Animals; Atherosclerosis; Cholesterol, HDL; Epigenesis, Genetic; Humans; Metabolic Diseases; Plaque, Atherosclerotic; Quinazolines; Quinazolinones

2015
[Novel therapy for atherosclerosis and inflammatory vascular disease].
    Nihon rinsho. Japanese journal of clinical medicine, 2011, Volume: 69, Issue:1

    Topics: Acetates; Amides; Apolipoprotein A-I; Atherosclerosis; Benzaldehydes; Blood Proteins; Cholesterol Ester Transfer Proteins; Clinical Trials as Topic; Drug Design; Esters; Humans; Indoles; Keto Acids; Molecular Targeted Therapy; Oxazolidinones; Oximes; Probucol; Quinazolines; Quinazolinones; Sulfhydryl Compounds

2011
Rvx 208.
    Drugs in R&D, 2011, Volume: 11, Issue:2

    Topics: Acute Coronary Syndrome; Alzheimer Disease; Animals; Atherosclerosis; Clinical Trials as Topic; Drug Evaluation, Preclinical; Humans; Quinazolines; Quinazolinones

2011

Other Studies

12 other study(ies) available for quinazolines and Atherosclerosis

ArticleYear
Rutaecarpine derivative R3 attenuates atherosclerosis via inhibiting NLRP3 inflammasome-related inflammation and modulating cholesterol transport.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2020, Volume: 34, Issue:1

    Topics: Animals; Atherosclerosis; Biological Transport, Active; Cholesterol; Indole Alkaloids; Inflammasomes; Inflammation; Macrophages; Mice; Mice, Knockout, ApoE; NLR Family, Pyrin Domain-Containing 3 Protein; Quinazolines

2020
Tryptanthrin Regulates Vascular Smooth Muscle Cell Phenotypic Switching in Atherosclerosis by AMP-Activated Protein Kinase/Acetyl-CoA Carboxylase Signaling Pathway.
    Journal of cardiovascular pharmacology, 2021, 05-01, Volume: 77, Issue:5

    Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Atherosclerosis; Becaplermin; Cell Plasticity; Cells, Cultured; Disease Models, Animal; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neointima; Phenotype; Phosphorylation; Plaque, Atherosclerotic; Quinazolines; Signal Transduction

2021
RVX-208, an inducer of ApoA-I in humans, is a BET bromodomain antagonist.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Animals; Apolipoprotein A-I; Atherosclerosis; Binding Sites; Cell Cycle Proteins; Cell Line; Crystallography, X-Ray; Epigenesis, Genetic; Hepatocytes; Humans; Models, Molecular; Nuclear Proteins; Protein Conformation; Protein Serine-Threonine Kinases; Quinazolines; Quinazolinones; Recombinant Proteins; RNA, Small Interfering; Transcription Factors

2013
The uremic toxin indoxyl sulfate acts as a pro- or antioxidant on LDL oxidation.
    Free radical research, 2014, Volume: 48, Issue:6

    Topics: Amidines; Antioxidants; Atherosclerosis; Copper; Hemin; Humans; Hydrogen Peroxide; Indican; Lipid Peroxidation; Lipid Peroxides; Lipoproteins, LDL; Oxidation-Reduction; Oxidative Stress; Peroxidase; Quinazolines; Renal Insufficiency, Chronic; Uremia

2014
Rutaecarpine suppresses atherosclerosis in ApoE-/- mice through upregulating ABCA1 and SR-BI within RCT.
    Journal of lipid research, 2014, Volume: 55, Issue:8

    Topics: Animals; Apolipoproteins E; Atherosclerosis; ATP Binding Cassette Transporter 1; Indole Alkaloids; Liver; Mice; Mice, Knockout; Quinazolines; RAW 264.7 Cells; Scavenger Receptors, Class B

2014
A novel BET bromodomain inhibitor, RVX-208, shows reduction of atherosclerosis in hyperlipidemic ApoE deficient mice.
    Atherosclerosis, 2014, Volume: 236, Issue:1

    Topics: Animals; Aorta; Aortic Diseases; Apolipoprotein A-I; Apolipoproteins E; Atherosclerosis; Betaine-Homocysteine S-Methyltransferase; Cell Line; Cholesterol, HDL; Cholesterol, LDL; Cytokines; Diet, Fat-Restricted; Diet, Western; Drug Evaluation, Preclinical; Endothelial Cells; Gene Expression Profiling; Humans; Hyperlipidemias; Inflammation; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Quinazolines; Quinazolinones; RNA, Messenger; U937 Cells

2014
Significance of vascular dipeptidyl peptidase-4 inhibition on vascular protection in Zucker diabetic fatty rats.
    Journal of pharmacological sciences, 2014, Volume: 125, Issue:4

    Topics: Animals; Atherosclerosis; Blood Glucose; Carotid Arteries; Chemokine CCL2; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Gene Expression; Glucose Tolerance Test; In Vitro Techniques; Insulin; Linagliptin; Malondialdehyde; NADPH Oxidases; Purines; Pyrazines; Quinazolines; Rats, Zucker; Sitagliptin Phosphate; Triazoles; Vasodilation

2014
Rutaecarpine Reverses the Altered Connexin Expression Pattern Induced by Oxidized Low-density Lipoprotein in Monocytes.
    Journal of cardiovascular pharmacology, 2016, Volume: 67, Issue:6

    Topics: Adenosine Triphosphate; Atherosclerosis; Cells, Cultured; Connexins; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Indole Alkaloids; Lipoproteins, LDL; Monocytes; Quinazolines; Time Factors

2016
RVX-208, a BET-inhibitor for treating atherosclerotic cardiovascular disease, raises ApoA-I/HDL and represses pathways that contribute to cardiovascular disease.
    Atherosclerosis, 2016, Volume: 247

    Topics: Apolipoprotein A-I; Atherosclerosis; Cardiovascular Diseases; Cells, Cultured; Cholesterol, HDL; Clinical Trials, Phase II as Topic; Dose-Response Relationship, Drug; Gene Expression Profiling; Hepatocytes; Humans; Hypolipidemic Agents; Liver; Male; Oligonucleotide Array Sequence Analysis; Quinazolines; Quinazolinones; Randomized Controlled Trials as Topic; Retrospective Studies; Signal Transduction; Time Factors; Up-Regulation

2016
Allele-specific regulation of matrix metalloproteinase-3 gene by transcription factor NFkappaB.
    PloS one, 2010, Mar-25, Volume: 5, Issue:3

    Topics: Alleles; Animals; Atherosclerosis; Gene Expression Regulation, Enzymologic; Genes, Dominant; Humans; Immunohistochemistry; Lipopolysaccharides; Matrix Metalloproteinase 3; Mice; Mutation; NF-kappa B; Polymorphism, Genetic; Promoter Regions, Genetic; Quinazolines

2010
Molecular mechanisms of activation of endothelial nitric oxide synthase mediated by transient receptor potential vanilloid type 1.
    Cardiovascular research, 2011, Aug-01, Volume: 91, Issue:3

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Capsaicin; Cattle; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Activation; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinazolines; RNA Interference; Signal Transduction; Time Factors; Transfection; TRPV Cation Channels

2011
Transactivation of fetal liver kinase-1/kinase-insert domain-containing receptor by lysophosphatidylcholine induces vascular endothelial cell proliferation.
    Endocrinology, 2006, Volume: 147, Issue:3

    Topics: Atherosclerosis; Benzoquinones; Blotting, Western; Cell Line; Cell Proliferation; Cell Survival; Cells, Cultured; Cinnamates; CSK Tyrosine-Protein Kinase; Disease Progression; Endothelial Cells; Endothelium, Vascular; Humans; Immunoblotting; Immunoprecipitation; Lactams, Macrocyclic; Ligands; Lysophosphatidylcholines; Phosphorylation; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Pyrimidines; Quinazolines; Quinones; Rifabutin; src-Family Kinases; Transcriptional Activation; Transfection; Vascular Endothelial Growth Factor Receptor-2

2006