Page last updated: 2024-08-21

quinazolines and Asthma, Bronchial

quinazolines has been researched along with Asthma, Bronchial in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199017 (39.53)18.7374
1990's0 (0.00)18.2507
2000's8 (18.60)29.6817
2010's16 (37.21)24.3611
2020's2 (4.65)2.80

Authors

AuthorsStudies
Fujita, A; Fukuyama, S; Ishii, Y; Kan-O, K; Matsumoto, K; Ogawa, T; Shiota, A1
Cui, Y; Wang, J; Wang, Q; Wu, X1
Akhtar, S; Babyson, RS; Benter, IF; El-Hashim, AZ; Ezeamuzie, C; Khajah, MA; Renno, WM; Uddin, M1
Baek, IH; Bhandary, B; Bhattarai, KR; Chae, HJ; Chai, OH; Handigund, M; Junjappa, RP; Kim, HK; Kim, HR; Lee, GH; Lee, HY; Lee, YC; Marahatta, A; Pyo, JS1
Inase, N; Miyazaki, Y; Okayasu, K; Sumi, Y; Takayama, S; Tamaoka, M; Yoshizawa, Y1
Bhat, WW; Ghosh, B; Lattoo, SK; Mabalirajan, U; Panda, L; Rasool, S; Rather, RA; Rayees, S; Satti, NK; Singh, G1
Bailie, K; Bell, J; Comer, D; Douglas, I; Heaney, LG; Parker, JC; Shields, MD; Skibinski, G1
Berhan, A; Harris, T; Keenan, CR; Langenbach, S; Royce, SG; Schuliga, M; Stewart, AG1
Li, Y; Liu, D; Qu, S; Song, J; Song, L; Tang, H; Wu, Y1
Broadley, KJ; Smith, N1
Li, XH; Luan, B1
Chung, CR; Han, HJ; Kim, SR; Lee, KS; Lee, MH; Lee, YC; Min, KH; Moon, H; Park, SJ; Puri, KD1
Al Heialy, S; Jo, T; Maghni, K; Martin, JG; Risse, PA; Shalaby, KH; Siddiqui, S; Takeda, N; Tsuchiya, K1
Li, H; Wang, Q; Xia, D; Yao, Y; Zhou, J1
Kim, SR; Lee, KS; Lee, YC; Min, KH; Moon, H; Park, HS; Park, SJ; Puri, KD1
Black, JL; Burgess, JK; Ge, Q; Moir, LM; Niimi, K; Oliver, BG; Poniris, M; Shepherd, PR; Trian, T1
Barnes, PJ; Ito, K; Ito, M; Osoata, G; Rossios, C; To, Y1
Chung, KF; Huang, CD; Huang, TT; Kuo, HP; Lee, KY; Lin, HC; Lin, SM; Lo, YL; Wang, CH1
Bahaie, NS; Blumenthal, MN; Ge, XN; Greenberg, Y; Ha, SG; Kang, BN; Puri, KD; Rao, SP; Reza Hosseinkhani, M; Sriramarao, P1
Long, HC; Wang, G; Wang, ZH; Wang, ZL; Xiao, BR1
Bacilieri, M; Bolcato, C; Cacciari, B; Moro, S; Pastorin, G; Spalluto, G1
Hayflick, JS; Lee, HK; Lee, KS; Lee, YC; Puri, KD1
Jin, SM; Kim, SR; Lee, KS; Lee, YC; Min, KH; Park, SJ; Puri, KD1
Cheng, S; Chow, CM; Marlin, GE; Reddel, HK; Thompson, PJ2
Barnes, P1
Barnes, PJ; Vickers, H; Wilson, NM1
Barnes, PJ; Dollery, CT; Ind, PW1
Fujimoto, T; Nakajima, S; Ohishi, M; Shiba, K; Takagi, O; Tsuya, Y; Uenishi, H1
Black, JL; Salome, C; Shaw, J; Yan, K1
Capiris, T; Herzig, DJ; Kesten, SJ; Sircar, JC1
Baird, JR; Blackburn, KJ; Cambridge, D; Constantine, JW; Ghaly, MS; Hayden, ML; McIlhenny, HM; Moore, PF; Olukotun, AY; Pullman, LG; Salsburg, DS; Saxton, CA; Shevde, S; Taylor, CR1
Bonner, JC; Wang, YZ1
Dal Piaz, V; Giovannoni, MP1
Atabai, K; Birch, M; Burgel, PR; Lazarus, SC; Nadel, JA; Tam, DC; Ueki, IF1
Dunton, AW; McGhee, B; Welton, AF1
Furukawa, K; Goto, S; Inagaki, N; Iwamoto, T; Koda, A; Matsuura, N; Mori, H; Nagai, H; Nishiyori, T; Yamada, H1
Misawa, M; Ohmori, S; Yanaura, S1
Ollrogge, M; Rinast, E; Wiessmann, KJ1
Ollrogge, M; Rinast, E; Schultek, T; Wiessmann, KJ; Wood, WG1
Muacević, G; Stötzer, H; Wick, H1
Bottke, H; Günthner, W1
Berenyi, KJ; Steen, SN1

Reviews

3 review(s) available for quinazolines and Asthma, Bronchial

ArticleYear
A2B adenosine receptor antagonists: recent developments.
    Mini reviews in medicinal chemistry, 2005, Volume: 5, Issue:12

    Topics: Adenosine A2 Receptor Antagonists; Amino Acid Sequence; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Binding Sites; Drug Design; Humans; Molecular Sequence Data; Quinazolines; Triazoles; Xanthines

2005
Comparative pharmacology and clinical efficacy of newer agents in treatment of heart failure.
    American heart journal, 1981, Volume: 102, Issue:3 Pt 2

    Topics: Animals; Asthma; Carbamates; Cardiotonic Agents; Cardiovascular Agents; Clinical Trials as Topic; Drug Evaluation; Drug Evaluation, Preclinical; Ethanolamines; Heart Failure; Hemodynamics; Humans; Hypertension; Piperazines; Prazosin; Quinazolines; Vasodilator Agents

1981
Phosphodiesterase 4 inhibitors, structurally unrelated to rolipram, as promising agents for the treatment of asthma and other pathologies.
    European journal of medicinal chemistry, 2000, Volume: 35, Issue:5

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Arthritis, Rheumatoid; Asthma; Cyclic Nucleotide Phosphodiesterases, Type 4; Humans; Isoenzymes; Lung Diseases, Obstructive; Molecular Structure; Phosphodiesterase Inhibitors; Quinazolines; Rolipram; Theophylline; Xanthines

2000

Trials

10 trial(s) available for quinazolines and Asthma, Bronchial

ArticleYear
Bronchodilator action of prazosin.
    Lancet (London, England), 1981, Jan-24, Volume: 1, Issue:8213

    Topics: Adult; Asthma; Bronchi; Bronchodilator Agents; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Phosphodiesterase Inhibitors; Prazosin; Quinazolines; Random Allocation

1981
Prazosin as bronchodilator.
    Lancet (London, England), 1981, Feb-14, Volume: 1, Issue:8216

    Topics: Asthma; Bronchodilator Agents; Clinical Trials as Topic; Double-Blind Method; Humans; Prazosin; Quinazolines

1981
Prazosin, an alpha 1-adrenoceptor antagonist, partially inhibits exercise-induced asthma.
    The Journal of allergy and clinical immunology, 1981, Volume: 68, Issue:6

    Topics: Adolescent; Adrenergic alpha-Agonists; Asthma; Asthma, Exercise-Induced; Child; Clinical Trials as Topic; Female; Forced Expiratory Volume; Histamine; Humans; Male; Peak Expiratory Flow Rate; Placebos; Prazosin; Quinazolines; Random Allocation; Vital Capacity

1981
Inhaled prazosin in asthma.
    Thorax, 1981, Volume: 36, Issue:5

    Topics: Adrenergic alpha-Antagonists; Adult; Albuterol; Asthma; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Lung; Male; Middle Aged; Prazosin; Quinazolines; Random Allocation; Respiration; Respiratory Function Tests

1981
Comparative pharmacology and clinical efficacy of newer agents in treatment of heart failure.
    American heart journal, 1981, Volume: 102, Issue:3 Pt 2

    Topics: Animals; Asthma; Carbamates; Cardiotonic Agents; Cardiovascular Agents; Clinical Trials as Topic; Drug Evaluation; Drug Evaluation, Preclinical; Ethanolamines; Heart Failure; Hemodynamics; Humans; Hypertension; Piperazines; Prazosin; Quinazolines; Vasodilator Agents

1981
The pharmacological profile and initial clinical evaluation of tiacrilast (Ro 22-3747): a new antiallergic agent.
    Agents and actions, 1986, Volume: 18, Issue:3-4

    Topics: Animals; Asthma; Bronchi; Clinical Trials as Topic; Cromolyn Sodium; Histamine H1 Antagonists; Histamine Release; Humans; Mast Cells; Passive Cutaneous Anaphylaxis; Quinazolines; Rats

1986
[Comparison of the anti-allergic and anti-asthmatic effects of SM 857 (Doqualast) and DNCG].
    Praxis und Klinik der Pneumologie, 1987, Volume: 41, Issue:2

    Topics: Adult; Asthma; Clinical Trials as Topic; Cromolyn Sodium; Double-Blind Method; Female; Humans; Male; Quinazolines; Respiratory Hypersensitivity

1987
[Protective effect of Sm 857 (Doqualast) in allergic bronchial asthma].
    Praxis und Klinik der Pneumologie, 1986, Volume: 40, Issue:11

    Topics: Administration, Oral; Adolescent; Adult; Asthma; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Quinazolines; Random Allocation; Respiratory Hypersensitivity

1986
[On the treatment of bronchial asthma with antihistaminics. Clinical and experimental results with 1-dimethylaminoethyl-2-alpha-pyridyl-4-oxo-1,2,3,4-tetrahydroquinazoline].
    Arzneimittel-Forschung, 1966, Volume: 16, Issue:11

    Topics: Asthma; Bronchial Diseases; Bronchial Spasm; Clinical Trials as Topic; Histamine H1 Antagonists; Humans; Placebos; Quinazolines; Spirometry

1966
Further observations on respiratory flow-volume loops: clinical evaluation of a new oral bronchodilator, CP-12,521-1.
    Canadian Anaesthetists' Society journal, 1970, Volume: 17, Issue:5

    Topics: Asthma; Bronchodilator Agents; Clinical Trials as Topic; Female; Humans; Male; Methods; Piperazines; Quinazolines; Spirometry; Valerates

1970

Other Studies

31 other study(ies) available for quinazolines and Asthma, Bronchial

ArticleYear
Inhibition of PI3Kδ Differentially Regulates Poly I:C- and Human Metapneumovirus-Induced PD-L1 and PD-L2 Expression in Human Bronchial Epithelial Cells.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Adenine; Asthma; B7-H1 Antigen; Bronchi; Cells, Cultured; Epithelial Cells; Gene Expression Regulation; Humans; Interferon Regulatory Factor-3; Interferons; Metapneumovirus; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Poly I-C; Programmed Cell Death 1 Ligand 2 Protein; Protein Serine-Threonine Kinases; Quinazolines

2021
Evodiamine protects against airway remodelling and inflammation in asthmatic rats by modulating the HMGB1/NF-κB/TLR-4 signalling pathway.
    Pharmaceutical biology, 2021, Volume: 59, Issue:1

    Topics: Airway Remodeling; Animals; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Evodia; HMGB1 Protein; Inflammation; NF-kappa B; Quinazolines; Rats; Rats, Sprague-Dawley; Signal Transduction; Toll-Like Receptor 4

2021
Src-dependent EGFR transactivation regulates lung inflammation via downstream signaling involving ERK1/2, PI3Kδ/Akt and NFκB induction in a murine asthma model.
    Scientific reports, 2017, 08-30, Volume: 7, Issue:1

    Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Down-Regulation; ErbB Receptors; Humans; Indoles; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; NF-kappa B; Ovalbumin; Phosphorylation; Proto-Oncogene Proteins pp60(c-src); Quinazolines; Signal Transduction; Sulfonamides; Transcriptional Activation; Tyrphostins

2017
PI3Kδ contributes to ER stress-associated asthma through ER-redox disturbances: the involvement of the RIDD-RIG-I-NF-κB axis.
    Experimental & molecular medicine, 2018, 02-16, Volume: 50, Issue:2

    Topics: Adenine; Animals; Asthma; Disease Models, Animal; Endoplasmic Reticulum Stress; Lipid Peroxidation; Lipopolysaccharides; Membrane Proteins; Mice; Nerve Tissue Proteins; NF-kappa B; Ovalbumin; Oxidation-Reduction; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Quinazolines; Reactive Oxygen Species; Receptors, Cell Surface; Signal Transduction

2018
RANTES expression induced by Toll-like receptor 4 ligand in rat airway smooth muscle cells.
    Journal of medical and dental sciences, 2010, Mar-01, Volume: 57, Issue:4

    Topics: Animals; Asthma; Cell Culture Techniques; Cells, Cultured; Chemokine CCL11; Chemokine CCL5; Chromones; Dipeptides; ErbB Receptors; Lipopolysaccharides; Male; Matrix Metalloproteinase Inhibitors; Morpholines; Myocytes, Smooth Muscle; Phosphoinositide-3 Kinase Inhibitors; Protein Tyrosine Phosphatases; Quinazolines; Rats, Inbred BN; Signal Transduction; Toll-Like Receptor 4; Trachea; Transcriptional Activation; Tyrphostins

2010
Therapeutic effects of R8, a semi-synthetic analogue of Vasicine, on murine model of allergic airway inflammation via STAT6 inhibition.
    International immunopharmacology, 2015, Volume: 26, Issue:1

    Topics: Alkaloids; Animals; Anti-Asthmatic Agents; Asthma; Azepines; Cytokines; Disease Models, Animal; Gene Expression; Immunoglobulin E; Lung; Male; Mice, Inbred BALB C; Ovalbumin; Quinazolines; Quinazolinones; STAT6 Transcription Factor; Toxicity Tests

2015
Epidermal Growth Factor Removal or Tyrphostin AG1478 Treatment Reduces Goblet Cells & Mucus Secretion of Epithelial Cells from Asthmatic Children Using the Air-Liquid Interface Model.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Adolescent; Air; Asthma; Bronchi; Cell Count; Cell Differentiation; Cell Proliferation; Cells, Cultured; Child; Child, Preschool; Electric Impedance; Epidermal Growth Factor; Female; Goblet Cells; Humans; Infant; Male; Models, Biological; Mucin 5AC; Quinazolines; RNA, Messenger; Tyrphostins

2015
The Coagulant Factor Xa Induces Protease-Activated Receptor-1 and Annexin A2-Dependent Airway Smooth Muscle Cytokine Production and Cell Proliferation.
    American journal of respiratory cell and molecular biology, 2016, Volume: 54, Issue:2

    Topics: Airway Remodeling; Annexin A2; Asthma; Biopsy; Cell Proliferation; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Factor Xa; Gene Expression Regulation; Humans; Integrin beta1; Myocytes, Smooth Muscle; Pyrroles; Quinazolines; Receptor, PAR-1; Respiratory System; RNA Interference; RNA, Messenger; Signal Transduction; Thrombin; Time Factors; Transfection

2016
The Chronic and Short-Term Effects of Gefinitib on Airway Remodeling and Inflammation in a Mouse Model of Asthma.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 38, Issue:1

    Topics: Airway Remodeling; Animals; Asthma; bcl-2-Associated X Protein; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Down-Regulation; Eosinophils; ErbB Receptors; Gefitinib; Inflammation; Interferon-gamma; Interleukin-13; Leukocyte Count; Male; Mice; Mice, Inbred BALB C; Mucin 5AC; Ovalbumin; Proto-Oncogene Proteins c-bcl-2; Quinazolines

2016
Adenosine receptor subtypes in the airways responses to 5'-adenosine monophosphate inhalation of sensitized guinea-pigs.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2008, Volume: 38, Issue:9

    Topics: Adenosine Monophosphate; Administration, Inhalation; Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchodilator Agents; Dexamethasone; Dose-Response Relationship, Drug; Guinea Pigs; Immunization; Purinergic P1 Receptor Antagonists; Purines; Quinazolines; Receptors, Purinergic P1; Triazines; Triazoles; Xanthines

2008
[Effect of epidermal growth factor receptor on airway remodeling in asthmatic mice and its mechanism].
    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2010, Volume: 12, Issue:2

    Topics: Airway Remodeling; Animals; Asthma; ErbB Receptors; Heparin-binding EGF-like Growth Factor; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Male; Mice; Quinazolines; Tyrphostins

2010
Phosphoinositide 3-kinase δ inhibitor suppresses interleukin-17 expression in a murine asthma model.
    The European respiratory journal, 2010, Volume: 36, Issue:6

    Topics: Adenine; Animals; Asthma; Bronchoalveolar Lavage Fluid; Chemotactic Factors; Eosinophils; Female; Interleukin-17; Interleukin-4; Interleukin-5; Lung; Lymphocytes; Mice; Mice, Inbred C57BL; Neutrophils; NF-kappa B; Nitriles; Phosphoinositide-3 Kinase Inhibitors; Quinazolines; Sulfones

2010
EGF receptor activation during allergic sensitization affects IL-6-induced T-cell influx to airways in a rat model of asthma.
    European journal of immunology, 2010, Volume: 40, Issue:6

    Topics: Allergens; Animals; Asthma; Blotting, Western; Bronchoalveolar Lavage Fluid; Cell Separation; Chemotaxis, Leukocyte; Cytokines; Disease Models, Animal; Enzyme Inhibitors; ErbB Receptors; Flow Cytometry; Interleukin-6; Lung; Ovalbumin; Quinazolines; Rats; Rats, Inbred BN; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes; Tyrphostins

2010
The overexpression of heparin-binding epidermal growth factor is responsible for Th17-induced airway remodeling in an experimental asthma model.
    Journal of immunology (Baltimore, Md. : 1950), 2010, Jul-15, Volume: 185, Issue:2

    Topics: Adoptive Transfer; Airway Remodeling; Animals; Antibodies, Monoclonal; Asthma; Blotting, Western; Cytokines; Disease Models, Animal; Enzyme Inhibitors; ErbB Receptors; Flow Cytometry; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Interleukin-17; Lung; Male; Mice; Mice, Inbred C57BL; Mucus; Ovalbumin; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes, Helper-Inducer; Tyrphostins

2010
HIF-1α inhibition ameliorates an allergic airway disease via VEGF suppression in bronchial epithelium.
    European journal of immunology, 2010, Volume: 40, Issue:10

    Topics: 2-Methoxyestradiol; Adenine; Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage Fluid; Endothelial Growth Factors; Epithelial Cells; Estradiol; Female; Histocytochemistry; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Inbred C57BL; Ovalbumin; Peptides, Cyclic; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Quinazolines; Respiratory Function Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Small Interfering; Signal Transduction; Specific Pathogen-Free Organisms; Vascular Endothelial Growth Factor A

2010
The phosphoinositide 3'-kinase p110δ modulates contractile protein production and IL-6 release in human airway smooth muscle.
    Journal of cellular physiology, 2012, Volume: 227, Issue:8

    Topics: Adenine; Adult; Aged; Aged, 80 and over; Asthma; Benzamides; Cells, Cultured; Chromones; Class I Phosphatidylinositol 3-Kinases; Contractile Proteins; Dioxoles; Female; Gene Expression Regulation; Humans; Interleukin-6; Lung; Male; Middle Aged; Morpholines; Muscle, Smooth; Phosphatidylinositol 3-Kinases; Pulmonary Disease, Chronic Obstructive; Quinazolines; Tissue Donors; Transforming Growth Factor beta1

2012
Corticosteroid insensitivity is reversed by formoterol via phosphoinositide-3-kinase inhibition.
    British journal of pharmacology, 2012, Volume: 167, Issue:4

    Topics: 1-Phosphatidylinositol 4-Kinase; Adenine; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists; Adult; Aged; Albuterol; Androstadienes; Asthma; Budesonide; Chromones; Dexamethasone; Drug Resistance; Ethanolamines; Female; Fluticasone; Formoterol Fumarate; Humans; Hydrogen Peroxide; Interleukin-8; Leukocytes, Mononuclear; Male; Middle Aged; Morpholines; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Quinazolines; Receptors, Adrenergic, beta-2; Salmeterol Xinafoate; U937 Cells; Young Adult

2012
Increased activation of fibrocytes in patients with chronic obstructive asthma through an epidermal growth factor receptor-dependent pathway.
    The Journal of allergy and clinical immunology, 2012, Volume: 129, Issue:5

    Topics: Acetylcysteine; ADAM Proteins; ADAM17 Protein; Adult; Antigens, CD34; Asthma; Blood Cells; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Collagen Type I; ErbB Receptors; Female; Fibroblasts; Follow-Up Studies; Gefitinib; Humans; Hydrogen Peroxide; Leukocyte Common Antigens; Male; Middle Aged; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Quinazolines; Respiratory Function Tests; Signal Transduction; Stem Cells; Tyrphostins

2012
The p110δ subunit of PI3K regulates bone marrow-derived eosinophil trafficking and airway eosinophilia in allergen-challenged mice.
    American journal of physiology. Lung cellular and molecular physiology, 2012, Jun-01, Volume: 302, Issue:11

    Topics: Adenine; Animals; Asthma; Bone Marrow Cells; Cell Adhesion; Cell Movement; Chemokine CCL11; Class I Phosphatidylinositol 3-Kinases; Eosinophilia; Eosinophils; Hypersensitivity; Intercellular Adhesion Molecule-1; Macrophage-1 Antigen; Methacholine Chloride; Mice; Mice, Inbred BALB C; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Quinazolines; Respiratory System; RNA Interference; RNA, Small Interfering; Vascular Cell Adhesion Molecule-1

2012
[Effect of tyrosine kinase inhibitors on airway remodeling in bronchial asthma].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2005, Volume: 36, Issue:1

    Topics: Animals; Asthma; Cells, Cultured; ErbB Receptors; Genistein; Male; Protein-Tyrosine Kinases; Quinazolines; Random Allocation; Rats; Rats, Sprague-Dawley; Trachea; Tyrphostins

2005
Inhibition of phosphoinositide 3-kinase delta attenuates allergic airway inflammation and hyperresponsiveness in murine asthma model.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:3

    Topics: Adenine; Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cell Adhesion Molecules; Chemokines; Chemotaxis, Leukocyte; Class I Phosphatidylinositol 3-Kinases; Cytokines; Eosinophilia; Female; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Models, Animal; Mucus; Ovalbumin; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Quinazolines

2006
Phosphoinositide 3-kinase-delta inhibitor reduces vascular permeability in a murine model of asthma.
    The Journal of allergy and clinical immunology, 2006, Volume: 118, Issue:2

    Topics: Adenine; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Capillary Permeability; Cinnamates; Class I Phosphatidylinositol 3-Kinases; Cytokines; Disease Models, Animal; Enzyme Inhibitors; Female; Hypoxia-Inducible Factor 1, alpha Subunit; Indoles; Leukocyte Count; Lung; Mice; Mice, Inbred BALB C; Ovalbumin; Phosphoinositide-3 Kinase Inhibitors; Pneumonia; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Vascular Endothelial Growth Factor A

2006
[Effects and site of action of alpha-receptor blocker in bronchial asthma].
    Nihon Kyobu Shikkan Gakkai zasshi, 1983, Volume: 21, Issue:5

    Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Aged; Asthma; Dinoprost; Female; Humans; Male; Metaproterenol; Middle Aged; Prostaglandins F; Quinazolines

1983
The action of prazosin and propylene glycol on methoxamine-induced bronchoconstriction in asthmatic subjects.
    British journal of clinical pharmacology, 1984, Volume: 18, Issue:3

    Topics: Adult; Aged; Asthma; Female; Forced Expiratory Volume; Histamine; Humans; Male; Methoxamine; Middle Aged; Prazosin; Propylene Glycols; Quinazolines

1984
Pyrazolo[5,1-b]quinazolin-9-ones: a new series of antiallergic agents.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:6

    Topics: Animals; Asthma; Cromolyn Sodium; Passive Cutaneous Anaphylaxis; Pyrazoles; Quinazolines; Rats; Structure-Activity Relationship

1981
Bronchodilator activity of prazosin in patients with allergic rhinitis and asthma.
    British journal of clinical pharmacology, 1982, Volume: 13, Issue:3

    Topics: Adult; Aged; Asthma; Blood Pressure; Bronchodilator Agents; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Prazosin; Pulse; Quinazolines; Rhinitis, Allergic, Perennial; Time Factors

1982
Mechanism of extracellular signal-regulated kinase (ERK)-1 and ERK-2 activation by vanadium pentoxide in rat pulmonary myofibroblasts.
    American journal of respiratory cell and molecular biology, 2000, Volume: 22, Issue:5

    Topics: Acetylcysteine; Animals; Asthma; Bronchitis; Carbon; Coal Ash; Colforsin; Enzyme Activation; ErbB Receptors; Fibroblasts; Flavonoids; Intracellular Signaling Peptides and Proteins; Lung; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Particulate Matter; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Quinazolines; Rats; Titanium; Tyrphostins; Vanadium Compounds

2000
Human eosinophils induce mucin production in airway epithelial cells via epidermal growth factor receptor activation.
    Journal of immunology (Baltimore, Md. : 1950), 2001, Nov-15, Volume: 167, Issue:10

    Topics: Adult; Asthma; Cells, Cultured; Culture Media, Conditioned; Enzyme Inhibitors; Eosinophils; ErbB Receptors; Humans; Hypersensitivity; Middle Aged; Mucin 5AC; Mucins; Phosphorylation; Pulmonary Eosinophilia; Quinazolines; Respiratory Mucosa; RNA, Messenger; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrphostins; Up-Regulation

2001
Effects of the new antiallergic drug 11-oxo-11H-pyrido[2,1-b] quinazoline-2-carboxylic acid on immediate allergic reactions.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:11

    Topics: Animals; Asthma; Guinea Pigs; Heart Rate; Histamine Release; Hypersensitivity, Immediate; Male; Muscle, Smooth; Passive Cutaneous Anaphylaxis; Quinazolines; Rats; Rats, Inbred Strains; Skin Tests; SRS-A; Tachyphylaxis

1986
Effects of the new antiallergic drug 11-oxo-11H-pyrido[2,1-b] quinazoline-2-carboxylic acid on bronchial and cutaneous allergic responses to ascaris in dogs.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:11

    Topics: Animals; Antigens, Helminth; Ascaris; Asthma; Bronchi; Dogs; Dose-Response Relationship, Drug; Hypersensitivity; Immunization; Male; ortho-Aminobenzoates; Passive Cutaneous Anaphylaxis; Quinazolines; Respiration

1986
[Pharmacologic properties of the antihistiminic 1-dimethylaminoethyl-2-alpha-pyridyl-4-oxo-1,2,3,4-tetrahydroquinazoline].
    Arzneimittel-Forschung, 1965, Volume: 15, Issue:6

    Topics: Anaphylaxis; Anesthetics, Local; Animals; Asthma; Bronchial Spasm; Drug Tolerance; Guinea Pigs; Histamine H1 Antagonists; Hypersensitivity; In Vitro Techniques; Quinazolines; Rats

1965