Page last updated: 2024-08-21

quinazolines and Anasarca

quinazolines has been researched along with Anasarca in 62 studies

Research

Studies (62)

Timeframe	Studies, this research(%)	All Research%
pre-1990	28 (45.16)	18.7374
1990's	6 (9.68)	18.2507
2000's	13 (20.97)	29.6817
2010's	13 (20.97)	24.3611
2020's	2 (3.23)	2.80

Authors

Authors	Studies
Karpenko, O; Kovalenko, S; Krasovska, N; Nosulenko, I; Stavytskyi, V; Voskoboinik, O	1
Abuelizz, HA; Al-Salahi, R; Ali, AA; Ezzeldin, E; Hassane, AE; Marzouk, M	1
Chaudhari, PS; Chitlange, SS; Nanda, RK	1
Antypenko, O; Berest, G; Kovalenko, S; Martynenko, Y; Nosulenko, I	1
Li, YQ; Sun, H; Xue, D	1
Eräsalo, H; Hämäläinen, M; Laavola, M; Leppänen, T; Moilanen, E; Nieminen, R	1
Abbas, AH; Abou El Ella, DA; Esmat, A; Ismail, NS; Serya, RA	1
Cima, MJ; Hochberg, FH; Ong, Q	1
Bhatnagar, SP; Laddha, SS	1
Amin, KM; Anwar, MM; Kamel, MM; Khedr, M; Syam, YM	1
Badiger, DS; Dandawate, PR; Ghaisas, MM; Gudasi, KB; Hoonur, RS; Nethaji, M; Padhye, SB; Patil, BR; Vadavi, RS	1
Adami, M; Coruzzi, G; de Esch, IJ; de Kanter, FJ; Istyastono, EP; Jongejan, A; Leurs, R; Smits, RA; van Dam, CM; Zuiderveld, OP	1
Abdalla, M; Ghorab, MM; Ismail, ZH	1
Badiger, DS; Gudasi, KB; Hunoor, RS; Magannavar, CV; Muchandi, IS; Patil, BR; Vadavi, RS	1
Ballabeni, V; Barocelli, E; Brullo, C; Bruno, O; Cichero, E; Domenichini, G; Flammini, L; Fossa, P; Giorgio, C; Rocca, M; Saccani, F	1
Sharma, RA; Singh, B	1
Fukazawa, T; Hayashi, H; Isobe, Y; Nagasaki, T; Takahashi, H; Tobe, M; Tomizawa, H	1
Hayashi, H; Isobe, Y; Nagasaki, T; Obara, F; Tobe, M; Tomizawa, H	1
Alagarsamy, V; Muthukumar, V; Pavalarani, N; Revathi, R; Vasanthanathan, P	1
Alagarsamy, V; Meena, S; Ramseshu, KV; Revathi, R; Vijayakumar, S	1
Hayashi, H; Isobe, Y; Nagasaki, T; Takahashi, H; Tobe, M; Tomizawa, H	1
BRAILOVSKY, D; ESTEVEZ, E; FERNANDEZ, E; ROMERO, T	1
GRIFFIN, R; STEIGMANN, F	1
BRENES, C; FARRERASVALENTI, P; ROZMAN, C	1
COOKE, AR	1
KOERTGE, P	1
Cerdá-Nicolás, M; Hamburger, M; Potterat, O; Recio, MC; Ríos, JL	1
Ahmad, M; Bachar, SC; Rahman, AM; Roy, TG; Saha, A; Sutradhar, RK	1
Chandrika, PM; Narsaiah, B; Rao, AR; Rao, JV; Reddy, NC; Sridhar, V; Yakaiah, T	1
Diacovo, TG; Puri, KD; Randis, TM; Zhou, H	1
Hodge, JV; Lubbe, WF	1
Amico Roxas, M; Bernardini, R; Caruso, A; Matera, M; Russo, F; Santagati, A; Santagati, M	1
Fujiwara, M; Noda, K; Saita, M; Soejima, Y; Takamori, M; Tsuji, M; Ueki, S	1
Bhalla, TN; Bhargava, KP; Gujrati, VR; Shanker, K; Sinha, JN; Verma, M	1
Abd el-Samii, ZK; el-Feky, SA	1
Gupta, PN; Mishra, P; Shakya, AK; Shukla, R; Srimal, RC	1
Barghash, AM; el-Ashmawy, MB; el-Bendary, ER; el-Kerdawy, MM; Shehata, IA	1
Caruso, A; Cutuli, VM; Mangano, NG; Modica, M; Santagati, A; Santagati, M	1
Caruso, A; Catena Cutuli, VM; Daidone, G; Maggio, B; Mangano, NG; Mantione, L; Plescia, S; Raffa, D	1
Alcaraz, MJ; Gonzalez-Tejero, A; Molina, P; Rioja, I; Tárraga, A; Terencio, MC; Ubeda, A	1
Diamantis, W; Ludwig, BJ; Sofia, RD	1
Awata, H; Inukai, T; Koga, Y; Kurokawa, H; Yanagi, Y	1
Magnati, G; Tirelli, F	1
Bargagna, A; Budetta, S; Cenicola, ML; De Santis, D; Donnoli, D; Longobardi, M; Losasso, C; Mariani, E; Marmo, E; Schenone, P	1
Barthwal, JP; Bhalla, TN; Gupta, GP; Kalsi, R; Pande, K; Parmar, SS	1
Fujimura, H; Hasegawa, J; Kyuki, K; Niwa, M; Tsurumi, K; Yasuda, K	1
Ishizuka, T; Iwasawa, Y; Oine, T; Ozaki, K; Yamada, Y	1
Fujimura, H; Hiramatsu, Y; Nozaki, M; Tamura, Y; Tsurumi, K	1
Awata, H; Inaba, S; Inukai, T; Komatsu, T; Sakai, Y; Yamamoto, H; Yamamoto, M	1
Lowenthal, DT; Shear, L	1
Coombs, RV; Danna, RP; Denzer, M; Hardtmann, GE; Huegi, B; Jukniewicz, E; Koletar, G; Koletar, J; Ott, H; Perrine, JW; Takesue, EI; Trapold, JH	1
Awata, H; Inaba, S; Saito, C; Yamamoto, H; Yamamoto, M	1
Hong, E	1
Craswell, PW; Ezzat, E; Kopstein, J; Moorhead, JF; Varghese, Z	1
Allison, ME; Dargie, HJ; Gray, MJ; Kennedy, AC	1
Davidov, M; Finnerty, FA; Fotiu, S; Mroczek, WJ	1
Glenn, EM; Lyster, SC; Rohloff, NA	1
Gunstone, RF; Njemo, D; Sabuka, EM; Shani, HG; Wing, AJ	1
Coyne, WC; Cusic, JW	1

Reviews

1 review(s) available for quinazolines and Anasarca

Article	Year
A severe dermatologic adverse effect related with gefitinib: case report and review of the literature. Journal of cancer research and therapeutics, 2013, Volume: 9 Suppl 2 Topics: Antineoplastic Agents; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Edema; Erythema; Gefitinib; Humans; Lung Neoplasms; Male; Middle Aged; Quinazolines	2013

Trials

1 trial(s) available for quinazolines and Anasarca

Article	Year
Antihypertensive efficacy of metolazone. Clinical pharmacology and therapeutics, 1974, Volume: 16, Issue:2 Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Body Weight; Chlorthalidone; Diuretics; Edema; Female; Humans; Hypertension; Hypokalemia; Male; Middle Aged; Placebos; Quinazolines	1974

Other Studies

60 other study(ies) available for quinazolines and Anasarca

Article	Year
Quinazoline-containing Hydrazydes of Dicarboxylic Acids and Products of Their Structural Modification: A Novel Class of Anti-inflammatory Agents. Acta chimica Slovenica, 2021, Volume: 68, Issue:2 Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Dicarboxylic Acids; Disease Models, Animal; Edema; Hydrazines; Inflammation; Quinazolines; Rats; Rats, Wistar	2021
Molecular modeling, enzyme activity, anti-inflammatory and antiarthritic activities of newly synthesized quinazoline derivatives. Future medicinal chemistry, 2017, Volume: 9, Issue:17 Topics: Animals; Antirheumatic Agents; Arthritis, Experimental; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Edema; Membrane Proteins; Molecular Docking Simulation; Molecular Structure; Quinazolines; Rats; Structure-Activity Relationship	2017
Synthesis and Biological Evaluation of Novel 2-(4-acetyl-3-methyl- 5-(arylamino) thiophen-2-yl)-3-arylquinazolin-4(3H)-one Derivatives as Potential Anti-inflammatory and Antioxidant Agents. Anti-inflammatory & anti-allergy agents in medicinal chemistry, 2018, Volume: 17, Issue:2 Topics: Animals; Anti-Inflammatory Agents; Biphenyl Compounds; Carrageenan; Diclofenac; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Free Radical Scavengers; Male; Mice; Molecular Structure; Nitric Oxide; Picrates; Quinazolines; Rats, Wistar; Structure-Activity Relationship; Thiophenes	2018
Directed Search of Anti-inflammatory Agents Among (3HQuinazoline- 4-ylidene)hydrazides of N-protected Amino acids and their Heterocyclization Products. Anti-inflammatory & anti-allergy agents in medicinal chemistry, 2020, Volume: 19, Issue:1 Topics: Amino Acids; Animals; Anti-Inflammatory Agents; Cyclization; Cyclooxygenase 1; Cyclooxygenase 2; Edema; Formaldehyde; Hydrazines; Molecular Docking Simulation; Quinazolines; Rats, Wistar	2020
PI3K inhibitors LY294002 and IC87114 reduce inflammation in carrageenan-induced paw oedema and down-regulate inflammatory gene expression in activated macrophages. Basic & clinical pharmacology & toxicology, 2015, Volume: 116, Issue:1 Topics: Adenine; Animals; Carrageenan; Chemokine CCL2; Chromones; Down-Regulation; Edema; Enzyme Inhibitors; Inflammation; Interleukin-6; Macrophages; Mice; Morpholines; Nitric Oxide Synthase Type II; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Quinazolines; Tumor Necrosis Factor-alpha	2015
Design, synthesis and biological evaluation of novel quinazoline-based anti-inflammatory agents acting as PDE4B inhibitors. Chemical & pharmaceutical bulletin, 2015, Volume: 63, Issue:2 Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Binding Sites; Cyclic Nucleotide Phosphodiesterases, Type 4; Disease Models, Animal; Drug Design; Edema; Gastric Mucosa; Humans; Male; Molecular Docking Simulation; Phosphodiesterase 4 Inhibitors; Protein Isoforms; Protein Structure, Tertiary; Quinazolines; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha	2015
Depot delivery of dexamethasone and cediranib for the treatment of brain tumor associated edema in an intracranial rat glioma model. Journal of controlled release : official journal of the Controlled Release Society, 2015, Nov-10, Volume: 217 Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Brain Neoplasms; Cells, Cultured; Dexamethasone; Drug Delivery Systems; Drug Liberation; Edema; Female; Glioma; Human Umbilical Vein Endothelial Cells; Protein Kinase Inhibitors; Quinazolines; Rats, Inbred F344	2015
A new therapeutic approach in Parkinson's disease: some novel quinazoline derivatives as dual selective phosphodiesterase 1 inhibitors and anti-inflammatory agents. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Animals; Anti-Inflammatory Agents; Child, Preschool; Cyclic Nucleotide Phosphodiesterases, Type 1; Drug Evaluation, Preclinical; Edema; Humans; Parkinson Disease; Phosphodiesterase Inhibitors; Quinazolines; Rats; Stomach Ulcer; Structure-Activity Relationship	2009
Synthesis, biological evaluation and molecular docking of novel series of spiro [(2H,3H) quinazoline-2,1'- cyclohexan]-4(1H)- one derivatives as anti-inflammatory and analgesic agents. European journal of medicinal chemistry, 2010, Volume: 45, Issue:6 Topics: Analgesics; Animals; Anti-Inflammatory Agents; Cyclohexanes; Cyclohexanones; Cyclooxygenase 2; Edema; Female; Male; Models, Molecular; Molecular Conformation; Quinazolines; Rats; Ulcer	2010
Transition metal complexes of 3-aryl-2-substituted 1,2-dihydroquinazolin-4(3H)-one derivatives: new class of analgesic and anti-inflammatory agents. European journal of medicinal chemistry, 2010, Volume: 45, Issue:6 Topics: Analgesics; Animals; Anti-Inflammatory Agents; Crystallography, X-Ray; Drug Design; Edema; Mice; Organometallic Compounds; Quinazolines; Rats; Spectrum Analysis; Transition Elements	2010
Synthesis and QSAR of quinazoline sulfonamides as highly potent human histamine H4 receptor inverse agonists. Journal of medicinal chemistry, 2010, Mar-25, Volume: 53, Issue:6 Topics: Animals; Anti-Inflammatory Agents; Binding, Competitive; Carrageenan; Edema; Humans; Kinetics; Models, Chemical; Molecular Structure; Quantitative Structure-Activity Relationship; Quinazolines; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Sulfonamides	2010
Synthesis and biological activities of some novel triazoloquinazolines and triazinoquinazolines containing benzenesulfonamide moieties. Arzneimittel-Forschung, 2010, Volume: 60, Issue:2 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Edema; Foot; Formaldehyde; Indicators and Reagents; Lethal Dose 50; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Quinazolines; Rats; Rats, Wistar; Spectrophotometry, Infrared; Sulfonamides; Triazines; Triazoles	2010
A study of anti-inflammatory and analgesic activity of new 2,3-disubstituted 1,2-dihydroquinazolin-4(3h)-one derivative and its transition metal complexes. Chemical & pharmaceutical bulletin, 2010, Volume: 58, Issue:5 Topics: Analgesics; Animals; Anti-Inflammatory Agents; Coordination Complexes; Edema; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Quinazolines; Rats; Rats, Wistar; Reference Standards; Spectrophotometry, Infrared; Subcutaneous Tissue; Transition Elements	2010
Synthesis of new 5,6-dihydrobenzo[h]quinazoline 2,4-diamino substituted and antiplatelet/antiphlogistic activities evaluation. Bioorganic & medicinal chemistry letters, 2012, Jan-15, Volume: 22, Issue:2 Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzopyrans; Dose-Response Relationship, Drug; Drug Design; Edema; Guinea Pigs; Mice; Models, Molecular; Molecular Structure; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Pyrimidines; Quinazolines; Rats; Stereoisomerism; Structure-Activity Relationship	2012
Anti-inflammatory and antimicrobial properties of pyrroloquinazoline alkaloids from Adhatoda vasica Nees. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2013, Mar-15, Volume: 20, Issue:5 Topics: Acetophenones; Alkaloids; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antifungal Agents; Benzylamines; Candida albicans; Carrageenan; Chemical Fractionation; Drug Evaluation, Preclinical; Edema; Escherichia coli; Justicia; Male; Microbial Sensitivity Tests; Plant Roots; Quinazolines; Rats; Rats, Wistar	2013
Discovery of quinazolines as a novel structural class of potent inhibitors of NF-kappa B activation. Bioorganic & medicinal chemistry, 2003, Feb-06, Volume: 11, Issue:3 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Edema; Hindlimb; Humans; Inhibitory Concentration 50; Jurkat Cells; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Quinazolines; Rats; Spleen; Structure-Activity Relationship; Transcriptional Activation; Tumor Necrosis Factor-alpha	2003
Structure-activity relationships of 6-fluoroquinazolines: dual-acting compounds with inhibitory activities toward both TNF-alpha production and T cell proliferation. Bioorganic & medicinal chemistry, 2003, Feb-20, Volume: 11, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Arthritis, Experimental; B-Lymphocytes; Cell Division; Concanavalin A; Depression, Chemical; Drug Design; Edema; Humans; In Vitro Techniques; Lipopolysaccharides; Magnetic Resonance Spectroscopy; Male; Mice; Neutrophils; Quinazolines; Rats; Rats, Sprague-Dawley; Spleen; Structure-Activity Relationship; T-Lymphocytes; Tumor Necrosis Factor-alpha	2003
Synthesis, analgesic and anti-inflammatory activities of some novel 2,3-disubstituted quinazolin-4(3H)-ones. Biological & pharmaceutical bulletin, 2003, Volume: 26, Issue:4 Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Edema; Mice; Pain Measurement; Quinazolines; Rats	2003
Synthesis and pharmacological investigation of some novel 2,3-disubstituted quinazolin-4(3H)-ones as analgesic and antiinflammatory agents. Die Pharmazie, 2003, Volume: 58, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Edema; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Quinazolines; Rats; Spectrophotometry, Infrared	2003
A novel structural class of potent inhibitors of NF-kappa B activation: structure-activity relationships and biological effects of 6-aminoquinazoline derivatives. Bioorganic & medicinal chemistry, 2003, Sep-01, Volume: 11, Issue:18 Topics: Aminoquinolines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Edema; Inflammation; Inhibitory Concentration 50; NF-kappa B; Quinazolines; Rats; Spleen; Structure-Activity Relationship; Transcriptional Activation; Tumor Necrosis Factor-alpha	2003
[2 new non-mercurial oral diuretics: quinethazone and cyclopenthiazide]. Revista medica de Chile, 1963, Volume: 91 Topics: Benzothiadiazines; Cyclopenthiazide; Diuretics; Edema; Heart Failure; Liver Cirrhosis; Quinazolines; Sulfonamides	1963
EVALUATION OF QUINETHAZONE, A NEW DIURETIC. Journal of the American Geriatrics Society, 1963, Volume: 11 Topics: Ascites; Coronary Disease; Diuretics; Edema; Hypertension; Liver Cirrhosis; Quinazolines; Rheumatic Heart Disease; Sulfonamides	1963
[CLINICAL STUDY OF A DIURETIC, QUINETHAZONE]. Medicina clinica, 1963, Volume: 41 Topics: Anuria; Ascites; Blood Chemical Analysis; Diuretics; Edema; Liver Cirrhosis; Pharmacology; Quinazolines; Statistics as Topic; Sulfonamides; Toxicology	1963
A CLINICAL TRIAL OF A NEW QUINAZOLINONE DIURETIC. The Medical journal of Australia, 1964, Aug-01, Volume: 2 Topics: Coronary Disease; Diuretics; Edema; Humans; Liver Cirrhosis; Nephrotic Syndrome; Organomercury Compounds; Quinazolines; Quinazolinones; Sulfonamides	1964
[CLINICAL STUDIES WITH A DIURETIC IN EDEMA PATIENTS]. Arzneimittel-Forschung, 1964, Volume: 14 Topics: Biomedical Research; Diuretics; Drug Therapy; Edema; Quinazolines; Sulfonamides; Toxicology	1964
Anti-inflammatory and antiallergic activity in vivo of lipophilic Isatis tinctoria extracts and tryptanthrin. Planta medica, 2006, Volume: 72, Issue:6 Topics: Administration, Cutaneous; Administration, Oral; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Carrageenan; Drugs, Chinese Herbal; Edema; Female; Hypersensitivity; Isatis; Mice; Phytotherapy; Plant Extracts; Plant Leaves; Quinazolines; Tetradecanoylphorbol Acetate	2006
Anti-inflammatory and analgesic alkaloid from Sida cordifolia linn. Pakistan journal of pharmaceutical sciences, 2007, Volume: 20, Issue:3 Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Carrageenan; Edema; Female; Male; Malvaceae; Mice; Pain Measurement; Plant Extracts; Quinazolines; Rats; Rats, Long-Evans; Reaction Time	2007
Synthesis of novel 4,6-disubstituted quinazoline derivatives, their anti-inflammatory and anti-cancer activity (cytotoxic) against U937 leukemia cell lines. European journal of medicinal chemistry, 2008, Volume: 43, Issue:4 Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Carrageenan; Cell Proliferation; Edema; Humans; Male; Quinazolines; Rats; Rats, Wistar; Structure-Activity Relationship; U937 Cells	2008
Role of PI3Kdelta and PI3Kgamma in inflammatory arthritis and tissue localization of neutrophils. European journal of immunology, 2008, Volume: 38, Issue:5 Topics: Adenine; Animals; Arthritis, Experimental; Chemotaxis, Leukocyte; Class I Phosphatidylinositol 3-Kinases; Class Ib Phosphatidylinositol 3-Kinase; Edema; Enzyme Inhibitors; Hindlimb; Isoenzymes; Leukotriene B4; Mice; Mice, Inbred NOD; Mice, Inbred Strains; Mice, Knockout; Mice, Transgenic; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Infiltration; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Quinazolines	2008
Combined alpha- and beta-adrenoceptor antagonism with prazosin and oxprenolol in control of severe hypertension in pregnancy. The New Zealand medical journal, 1981, Sep-09, Volume: 94, Issue:691 Topics: Acute Disease; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adult; Drug Therapy, Combination; Edema; Female; Humans; Hypertension; Infant, Newborn; Infant, Newborn, Diseases; Oxprenolol; Prazosin; Pregnancy; Pregnancy Complications, Cardiovascular; Proteinuria; Quinazolines	1981
[Synthesis and pharmacological activity of 1,3,4-thiadiazolo[2,-3-b]benzo[g]quinazolin-5-one and benzo[g]quinazolin-4-one derivatives]. Il Farmaco; edizione scientifica, 1982, Volume: 37, Issue:7 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chemistry; Drug Evaluation, Preclinical; Edema; Male; Quinazolines; Rats; Rats, Inbred Strains	1982
[Effects of quinazoline-2, 4(1H, 3H)-dione compound, H-88 and pyridopyrimidine-2, 4(1H, 3H)-dione compound, HN-37 on pituitary-adrenal axis in rats (author's transl)]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1980, Volume: 76, Issue:8 Topics: Adrenal Glands; Adrenalectomy; Animals; Ascorbic Acid; Circadian Rhythm; Corticosterone; Dose-Response Relationship, Drug; Edema; Hypophysectomy; Male; Organ Size; Pituitary-Adrenal System; Pyrimidinones; Quinazolines; Rats	1980
A new potent anti-inflammatory quinazolone. Pharmacological research communications, 1981, Volume: 13, Issue:10 Topics: Animals; Anti-Inflammatory Agents; Blood Pressure; Cats; Edema; Female; Heart Rate; Lethal Dose 50; Male; Mice; Motor Activity; Phenylbutazone; Quinazolines; Quinazolinones; Rats; Stomach Ulcer; Structure-Activity Relationship	1981
Synthesis and antiinflammatory properties of some novel thiazolidinones and imidazolidinones derived from 4-(3-phenyl-4(3H)-quinazolinon-2-yl)-3-thiosemicarbazone. Die Pharmazie, 1995, Volume: 50, Issue:5 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Edema; Female; Imidazoles; Lethal Dose 50; Male; Quinazolines; Rats; Stomach Ulcer; Thiadiazoles	1995
Anti-inflammatory and diuretic activity of a new class of compounds--Schiff bases of 3-amino-2-methylquinazolin 4(3H)-ones. Indian journal of physiology and pharmacology, 1995, Volume: 39, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diuretics; Edema; Female; Furosemide; Lethal Dose 50; Male; Mice; Phenylbutazone; Quinazolines; Rats; Rats, Sprague-Dawley; Schiff Bases; Structure-Activity Relationship	1995
Synthesis of some new quinazolines and quinoxalines of potential antiinflammatory activity. Bollettino chimico farmaceutico, 1996, Volume: 135, Issue:11 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Edema; Quinazolines; Quinoxalines; Rats	1996
Anagrelide for essential thrombocythemia. The Medical letter on drugs and therapeutics, 1997, Dec-19, Volume: 39, Issue:1016 Topics: Adult; Child; Child, Preschool; Dose-Response Relationship, Drug; Edema; Fees, Pharmaceutical; Humans; Hypotension; Platelet Aggregation Inhibitors; Quinazolines; Tachycardia; Thrombocytosis	1997
Synthesis and pharmacological screening of 1,3,4-thiadiazino[2,3-b]quinazoline derivatives. Die Pharmazie, 2000, Volume: 55, Issue:10 Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Carrageenan; Edema; Lethal Dose 50; Male; Mice; Pain Measurement; Peritonitis; Quinazolines; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Structure-Activity Relationship; Thiadiazines	2000
Synthesis and pharmacological study of ethyl 1-methyl-5-(substituted 3,4-dihydro-4-oxoquinazolin-3-yl)-1H-pyrazole-4-acetates. European journal of medicinal chemistry, 2001, Volume: 36, Issue:9 Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzoquinones; Edema; Lethal Dose 50; Magnetic Resonance Spectroscopy; Male; Mice; Peritonitis; Pyrazoles; Quinazolines; Rats; Rats, Sprague-Dawley; Spectrophotometry, Infrared; Stomach Ulcer	2001
A pyrroloquinazoline derivative with anti-inflammatory and analgesic activity by dual inhibition of cyclo-oxygenase-2 and 5-lipoxygenase. European journal of pharmacology, 2002, Jan-11, Volume: 434, Issue:3 Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Edema; Enzyme Inhibitors; Female; Humans; Isoenzymes; Lipoxygenase Inhibitors; Membrane Proteins; Mice; Monocytes; Pain Measurement; Prostaglandin-Endoperoxide Synthases; Pyrroles; Quinazolines; Quinolines; Sheep	2002
Pharmacological properties of 2,3-dihydro-9H-isoxazolo [3,2-b] quinazolin-9-one (W-2429. Part 1: Analgesic, antipyretic and antiedema activity. Arzneimittel-Forschung, 1977, Volume: 27, Issue:4 Topics: Administration, Oral; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Body Temperature; Dextropropoxyphene; Drug Interactions; Drug Tolerance; Edema; Fever; Humans; Injections, Intravenous; Isoxazoles; Lethal Dose 50; Male; Mice; Narcotic Antagonists; Oxazoles; Quinazolines; Rats; Substance-Related Disorders; Time Factors	1977
[Anti-inflammatory activity of SL-573 (author's transl)]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1978, Volume: 74, Issue:6 Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Capillary Permeability; Depression, Chemical; Edema; Granuloma; Intestinal Perforation; Male; Mice; Quinazolines; Quinazolinones; Rats; Wound Healing	1978
[Clinical studies on the diuretic and saluretic activity of a new quinazolone derivative]. La Clinica terapeutica, 1975, Apr-15, Volume: 73, Issue:1 Topics: Adult; Aged; Diuretics; Edema; Female; Humans; Male; Middle Aged; Quinazolines; Sulfonamides; Water-Electrolyte Balance	1975
2H-pyrano[2,3-f]quinazoline derivatives with platelet antiaggregating and other activities. Farmaco (Societa chimica italiana : 1989), 1991, Volume: 46, Issue:1 Topics: Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Edema; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Mice; Platelet Aggregation Inhibitors; Pyrans; Quinazolines; Rats; Spectrophotometry, Infrared; Structure-Activity Relationship	1991
Anti-inflammatory activity of quinazolinoformazans. Journal of pharmaceutical sciences, 1990, Volume: 79, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Azo Compounds; Carrageenan; Chemical Phenomena; Chemistry; Edema; Female; Formazans; Male; Mice; Quinazolines; Rats; Stomach Ulcer	1990
Effect of the new antiallergic drug 11-oxo-11H-pyrido[2,1-b]quinazoline-2-carboxylic acid on inflammatory reactions and platelet aggregation. Arzneimittel-Forschung, 1986, Volume: 36, Issue:11 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Diarrhea; Edema; Erythema; Guinea Pigs; Hypersensitivity; Male; Mice; Platelet Aggregation; Quinazolines; Rats; Rats, Inbred Strains; Wound Healing	1986
Studies on 4(1H)-quinazolinones. 5. Synthesis and antiinflammatory activity of 4(1H)-quinazolinone derivatives. Journal of medicinal chemistry, 1985, Volume: 28, Issue:5 Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Edema; Male; Mice; Mice, Inbred Strains; Quinazolines; Rats; Rats, Inbred Strains; Stomach Ulcer; Structure-Activity Relationship	1985
Metolazone. The Medical letter on drugs and therapeutics, 1974, Sep-13, Volume: 16, Issue:19 Topics: Diuretics; Edema; Humans; Hypertension; Quinazolines; Sulfonamides	1974
[Pharmacological studies on quinazoline-2, 4-dione derivaties, H-27 and H-88: (1) anti-inflammatory, analgesic and antipyretic activities]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1974, Volume: 70, Issue:5 Topics: Adrenalectomy; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Body Temperature; Body Weight; Capillary Permeability; Cordotomy; Drug Evaluation, Preclinical; Edema; Erythema; Female; Granulation Tissue; Hemolysis; Lethal Dose 50; Male; Mice; Quinazolines; Rabbits; Rats	1974
New drugs--No. 12. Metolazone (zaroxolyn). Journal of the Irish Medical Association, 1972, Oct-27, Volume: 66, Issue:20 Topics: Antihypertensive Agents; Diuretics; Dose-Response Relationship, Drug; Drug Evaluation; Edema; Heart Failure; Hypertension; Kidney Diseases; Quinazolines; Sulfonamides	1972
Novel quinazoline derivatives. I. Synthesis and preliminary pharmacological evaluation of an anti-inflammatory agent, SL-573. Arzneimittel-Forschung, 1972, Volume: 22, Issue:11 Topics: Administration, Oral; Analgesics; Animals; Anisoles; Anti-Inflammatory Agents; Arthritis; Capillary Permeability; Chemical Phenomena; Chemistry; Edema; Granuloma; Male; Mefenamic Acid; Mice; Phenylbutazone; Quinazolines; Rats	1972
Use of a new diuretic agent (metolazone) in patients with edema and ascites. Archives of internal medicine, 1973, Volume: 132, Issue:1 Topics: Ascites; Blood Urea Nitrogen; Creatinine; Diuretics; Edema; Furosemide; Humans; Injections, Intravenous; Kidney Diseases; Liver Cirrhosis; Natriuresis; Potassium; Protein Binding; Quinazolines; Sodium; Sulfonamides; Time Factors; Urea	1973
Synthesis and antiinflammatory activity of 1-alkyl-4-aryl-2(1H)-quinazolinones and quinazolinethiones. Journal of medicinal chemistry, 1973, Volume: 16, Issue:11 Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Arthritis; Bradykinin; Carrageenan; Edema; Foot; Guinea Pigs; Hyperesthesia; Ketones; Quinazolines; Rats; Structure-Activity Relationship; Thiones	1973
Novel quinazoline derivatives. II. A new anti-inflammatory agent, SL-512. Arzneimittel-Forschung, 1973, Volume: 23, Issue:9 Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Capillary Permeability; Cyclopropanes; Edema; Erythema; Granuloma; Guinea Pigs; Intestinal Perforation; Lethal Dose 50; Male; Mefenamic Acid; Mice; Peritonitis; Phenylbutazone; Quinazolines; Rats	1973
On the antiserotonin activity of 6-acetamido-3(3-(4-phenyl-1-piperazinyl)-propyl)-284(1h,3h)-quinazolinedione-maleate (MA 1420). Arzneimittel-Forschung, 1973, Volume: 23, Issue:12 Topics: Animals; Aorta, Thoracic; Blood Pressure; Chlorisondamine; Cyproheptadine; Dogs; Drug Evaluation, Preclinical; Edema; Female; Guinea Pigs; Lung; Methysergide; Piperazines; Quinazolines; Rabbits; Rats; Serotonin Antagonists; Uterus	1973
Use of metolazone, a new diuretic, in patients with renal disease. Nephron, 1974, Volume: 12, Issue:1 Topics: Administration, Oral; Adult; Antihypertensive Agents; Blood Glucose; Blood Pressure; Creatinine; Diuretics; Edema; Female; Glomerular Filtration Rate; Humans; Hypertension; Injections, Intravenous; Inulin; Kidney Diseases; Liver Function Tests; Male; Middle Aged; Potassium; Quinazolines; Renin; Sodium; Sulfonamides; Uric Acid	1974
Efficacy of metolazone in patients with renal edema. Clinical nephrology, 1974, Volume: 2, Issue:4 Topics: Adolescent; Adult; Aged; Body Weight; Diuresis; Diuretics; Drug Evaluation; Edema; Female; Glomerular Filtration Rate; Humans; Male; Middle Aged; Nephrosis; Potassium; Quinazolines; Sulfonamides	1974
Antiarthritic effects of the antispermatogenic agent 2,3-dihydro-(1-naphthyl)-4-(1H)-quinazolinone (U-29,409). Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1971, Volume: 138, Issue:1 Topics: Administration, Oral; Animals; Arthritis; Body Weight; Carrageenan; Cyclophosphamide; Dosage Forms; Drug Synergism; Edema; Encephalomyelitis, Autoimmune, Experimental; Female; Ketones; Leukocytes; Male; Naphthalenes; Organ Size; Quinazolines; Rats; Rats, Inbred Strains; Sex Factors	1971
Clinical experience with metolazone in fifty-two African patients: synergy with frusemide. Postgraduate medical journal, 1971, Volume: 47, Issue:554 Topics: Adult; Black People; Body Weight; Diuretics; Drug Synergism; Edema; Female; Furosemide; Humans; Ketones; Male; Middle Aged; Quinazolines; Sulfonamides	1971
3,4-dihydro-2(1H)-quinazolinones. Journal of medicinal chemistry, 1968, Volume: 11, Issue:6 Topics: Alkylation; Animals; Anti-Inflammatory Agents; Carrageenan; Edema; Phenylbutazone; Quinazolines; Rats	1968