quinazolines has been researched along with Allodynia in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (15.38) | 29.6817 |
| 2010's | 18 (69.23) | 24.3611 |
| 2020's | 4 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, J; Li, C; Li, Z; Lin, J; Lu, H; Wu, Z; Yang, X; Zhang, X; Zhang, Y | 1 |
| Bogacka, J; Ciechanowska, A; Dobrogowski, J; Makuch, W; Mika, J; Pawlik, K; Popiolek-Barczyk, K; Przeklasa-Muszynska, A; Rojewska, E | 1 |
| Kayama, Y; Kitagawa, S; Nakahara, J; Shibata, M; Takizawa, T; Tang, C; Unekawa, M | 1 |
| Gomez, K; Khanna, R; Moutal, A; Patek, M; Perez-Miller, S; Ran, D | 1 |
| Dallel, R; Descheemaeker, A; Luccarini, P | 1 |
| Araldi, D; Ferrari, LF; Levine, JD | 1 |
| Li, JX; Seaman, RW; Shang, L; Siemian, JN; Zhang, Y; Zhu, Q | 1 |
| Mohapatra, DP; Shepherd, AJ; Shutov, LP; Usachev, YM; Warwick, CA | 1 |
| Kovalenko, S; Kramar, H; Stepaniuk, H; Taran, I; Voloshchuk, N | 1 |
| Bellampalli, SS; Chefdeville, A; Chew, LA; Colecraft, HM; François-Moutal, L; Gokhale, V; Ha, T; Khanna, M; Khanna, R; Luo, S; Moutal, A; Park, KD; Patwardhan, AM; Perez-Miller, S; Serafini, MJ; Shuja, Z; Streicher, JM; Yang, X; Yu, J | 1 |
| Chen, JL; Ding, HL; Li, WB; Liu, BL; Liu, XG; Su, MZ; Xie, JC; Xu, YC; Yang, F; Zhan, HL; Zhou, X; Zhou, XF | 1 |
| Andersen, HH; Kullander, K; Lagerström, MC; Rogoz, K | 1 |
| Bastian, G; Bourgoin, S; Hamon, M; Kayser, V; Michot, B | 1 |
| Caselli, G; Ferrari, F; Lanza, M; Menghetti, I; Tremolada, D | 1 |
| Gao, F; Liu, T; Manyande, A; Tian, X; Tian, Y; Xiang, H; Xiang, Y; Yang, H | 1 |
| Aoki, S; Dai, Y; Iwaoka, E; Kogure, Y; Matsuyoshi, N; Noguchi, K; Wang, S; Yamamoto, S | 1 |
| Andrew, D; De Felice, M; Escott, KJ; Holen, I; Lambert, D | 1 |
| Altenbach, RJ; Brioni, JD; Carr, TL; Chandran, P; Cowart, MD; Esbenshade, TA; Honore, P; Hsieh, GC; Lewis, LG; Liu, H; Manelli, AM; Marsh, KC; Milicic, I; Miller, TR; Strakhova, MI; Vortherms, TA; Wakefield, BD; Wetter, JM; Witte, DG | 1 |
| Bakthavatchalam, R; Blum, CA; Boyce, S; Brielmann, H; Burnaby-Davies, N; Caldwell, T; Capitosti, S; Chenard, BL; Conley, R; Cortright, D; Crandall, M; De Lombaert, S; Hodgetts, KJ; Jones, AB; Kershaw, MT; Krause, JE; Martin, WJ; Mason, G; Matson, D; Murphy, BA; Perrett, H; Rycroft, W; Zheng, X | 1 |
| Cavazzini, A; De Siena, G; Failli, P; Gees, M; Geppetti, P; Harrison, S; Mancini, F; Marchetti, N; Materazzi, S; Moretto, N; Nassini, R; Nilius, B; Patacchini, R; Pedretti, P; Preti, D | 1 |
| Ma, F; Westlund, KN; Zhang, L | 1 |
| Bourgoin, S; Hamon, M; Kayser, V; Michot, B; Viguier, F | 1 |
| Bayburt, EK; Didomenico, S; Drizin, I; Faltynek, CR; Gomtsyan, A; Hannick, SM; Honore, P; Jarvis, MF; Jinkerson, T; Koenig, JR; Lee, CH; Macri, BS; Marsh, KC; McDonald, HA; Oie, T; Perner, RJ; Schmidt, RG; Stewart, KD; Surowy, CS; Turner, S; Wetter, J; Wismer, CT; Zheng, GZ | 1 |
| Dolle, RE; Koblish, M; LaBuda, CJ; Little, PJ; Tuthill, P | 1 |
| Ma, W; Quirion, R | 1 |
26 other study(ies) available for quinazolines and Allodynia
| Article | Year |
|---|---|
Evodiamine via targeting nNOS and AMPA receptor GluA1 inhibits nitroglycerin-induced migraine-like response.
Topics: Analgesics; Animals; Hyperalgesia; Male; Migraine Disorders; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitroglycerin; Pain; Periaqueductal Gray; Quinazolines; Rats, Sprague-Dawley; Receptors, AMPA | 2020 |
CCR4 antagonist (C021) influences the level of nociceptive factors and enhances the analgesic potency of morphine in a rat model of neuropathic pain.
Topics: Analgesics, Opioid; Animals; Cold Temperature; Cytokines; Disease Models, Animal; Drug Synergism; Ganglia, Spinal; Hyperalgesia; Male; Mice; Morphine; Neuralgia; Peripheral Nerve Injuries; Quinazolines; Rats, Wistar; Receptors, CCR4; Sciatic Nerve; Spinal Cord; Touch | 2020 |
Cortical spreading depolarisation-induced facial hyperalgesia, photophobia and hypomotility are ameliorated by sumatriptan and olcegepant.
Topics: Animals; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Cerebral Cortex; Chronic Pain; Cortical Spreading Depression; Dipeptides; Electrodes; Face; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Migraine with Aura; Movement; Photophobia; Piperazines; Prevalence; Quinazolines; Receptors, Serotonin; Serotonin 5-HT1 Receptor Agonists; Sumatriptan; Temperature | 2020 |
Comparison of quinazoline and benzoylpyrazoline chemotypes targeting the CaVα-β interaction as antagonists of the N-type CaV2.2 channel.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Hyperalgesia; Quinazolines; Rats | 2021 |
Recurrent administration of the nitric oxide donor, isosorbide dinitrate, induces a persistent cephalic cutaneous hypersensitivity: A model for migraine progression.
Topics: Animals; Central Nervous System Sensitization; Dipeptides; Disease Models, Animal; Hyperalgesia; Isosorbide Dinitrate; Male; Migraine Disorders; Nitric Oxide Donors; Piperazines; Quinazolines; Rats; Rats, Sprague-Dawley; Sumatriptan; Vasoconstrictor Agents; Vasodilator Agents | 2018 |
Role of GPCR (mu-opioid)-receptor tyrosine kinase (epidermal growth factor) crosstalk in opioid-induced hyperalgesic priming (type II).
Topics: Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Hyperalgesia; Male; Nociceptors; Pain Threshold; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Signal Transduction; Tyrphostins | 2018 |
Effects of imidazoline I2 receptor agonists on reserpine-induced hyperalgesia and depressive-like behavior in rats.
Topics: Analgesics; Animals; Benzofurans; Depression; Disease Models, Animal; Fibromyalgia; Hyperalgesia; Idazoxan; Imidazoles; Imidazoline Receptors; Imidazolines; Male; Pain; Pain Measurement; Quinazolines; Rats; Rats, Sprague-Dawley; Reserpine | 2019 |
Mechanisms underlying mechanical sensitization induced by complement C5a: the roles of macrophages, TRPV1, and calcitonin gene-related peptide receptors.
Topics: Acrylamides; Animals; Bridged Bicyclo Compounds, Heterocyclic; Complement C5a; Dipeptides; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hyperalgesia; Macrophages; Male; Mice; Mice, Inbred C57BL; Nerve Growth Factor; Pain Measurement; Piperidines; Quinazolines; Quinuclidines; Receptors, Calcitonin Gene-Related Peptide; Repressor Proteins; TRPA1 Cation Channel; TRPV Cation Channels | 2019 |
EXPERIMENTAL STUDY OF PAIN-RELIEVING MECHANISMS OF 4-[4-OXO-(4H)-QUINAZOLIN-3-YL]-BENZOIC ACID (PK-66 COMPOUND).
Topics: Administration, Oral; Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Benzoates; Dopamine D2 Receptor Antagonists; Drug Evaluation, Preclinical; Hot Temperature; Hyperalgesia; Injections, Intraperitoneal; Male; Pain; Quinazolines; Rats, Wistar | 2018 |
Targeting the CaVα-CaVβ interaction yields an antagonist of the N-type CaV2.2 channel with broad antinociceptive efficacy.
Topics: Analgesics; Animals; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Calcium Channels; Calcium Channels, N-Type; CHO Cells; Computer Simulation; Cricetulus; Excitatory Postsynaptic Potentials; Ganglia, Spinal; Hyperalgesia; Male; Neuralgia; Primary Cell Culture; Quinazolines; Rats; Rats, Sprague-Dawley; Spinal Cord | 2019 |
Neuregulin-1-ErbB signaling promotes microglia activation contributing to mechanical allodynia of cyclophosphamide-induced cystitis.
Topics: Animals; Cystitis; Female; Hyperalgesia; Injections, Spinal; Macrophage Activation; Microglia; Neuregulin-1; Oncogene Proteins v-erbB; Quinazolines; Rats; Rats, Sprague-Dawley; Signal Transduction | 2019 |
Glutamate, substance P, and calcitonin gene-related peptide cooperate in inflammation-induced heat hyperalgesia.
Topics: Androstanes; Animals; Benzimidazoles; Calcitonin Gene-Related Peptide; Female; Glutamic Acid; Hot Temperature; Hyperalgesia; Inflammation; Male; Mice; Nerve Growth Factor; Neurons, Afferent; Piperazines; Quinazolines; Substance P; TRPV Cation Channels; Vesicular Glutamate Transport Protein 2 | 2014 |
Differential pharmacological alleviation of oxaliplatin-induced hyperalgesia/allodynia at cephalic versus extra-cephalic level in rodents.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amines; Analgesics; Animals; Cold Temperature; Cyclohexanecarboxylic Acids; Dipeptides; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Morphine; Organoplatinum Compounds; Oxaliplatin; Piperazines; Piperidines; Quinazolines; Rats; Rats, Sprague-Dawley; Spinal Cord; Touch; TRPA1 Cation Channel; TRPC Cation Channels; Tryptamines | 2014 |
Modulation of imidazoline I2 binding sites by CR4056 relieves postoperative hyperalgesia in male and female rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Analgesics, Opioid; Animals; Benzofurans; Binding Sites; Drug Synergism; Female; Hyperalgesia; Idazoxan; Imidazoles; Imidazoline Receptors; Male; Morphine; Naloxone; Narcotic Antagonists; Pain, Postoperative; Quinazolines; Rats, Sprague-Dawley; Yohimbine | 2014 |
NRG1-ErbB signalling promotes microglia activation contributing to incision-induced mechanical allodynia.
Topics: Animals; Foot Injuries; Hyperalgesia; Injections, Spinal; Macrophage Activation; Male; Mice; Mice, Inbred C57BL; Microglia; Neuregulin-1; Oncogene Proteins v-erbB; Pain, Postoperative; Physical Stimulation; Quinazolines; RNA, Small Interfering; Signal Transduction; Spinal Cord; Suppression, Genetic; Up-Regulation | 2015 |
Evodiamine suppresses capsaicin-induced thermal hyperalgesia through activation and subsequent desensitization of the transient receptor potential V1 channels.
Topics: Alkaloids; Analgesics; Animals; Calcium; Calcium Channels; Capsaicin; Dose-Response Relationship, Drug; Evodia; Ganglia, Spinal; HEK293 Cells; Hot Temperature; Humans; Hyperalgesia; Male; Medicine, Chinese Traditional; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Plant Extracts; Quinazolines; Quinolines; Rats; Rats, Sprague-Dawley; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels | 2016 |
Effects of Src-kinase inhibition in cancer-induced bone pain.
Topics: Animals; Behavior, Animal; Benzodioxoles; Bone Neoplasms; Bone Remodeling; Bone Resorption; Cancer Pain; Disease Models, Animal; Hyperalgesia; Male; Neurons; Phosphorylation; Protein Kinase Inhibitors; Quinazolines; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; src-Family Kinases | 2016 |
The role of spinal thrombin through protease-activated receptor 1 in hyperalgesia after neural injury.
Topics: Animals; Antithrombins; Capillary Permeability; Central Nervous System Agents; Cervical Vertebrae; Disease Models, Animal; Fibrin; Hirudins; Hyperalgesia; Injections, Spinal; Male; Pain; Pain Measurement; Peripheral Nervous System Diseases; Pyrroles; Quinazolines; Radiculopathy; Rats, Sprague-Dawley; Receptor, PAR-1; Spinal Cord | 2017 |
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Humans; Hyperalgesia; Ligands; Mice; Molecular Structure; Pain; Peritonitis; Quinazolines; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Stereoisomerism; Structure-Activity Relationship | 2008 |
Discovery of novel 6,6-heterocycles as transient receptor potential vanilloid (TRPV1) antagonists.
Topics: Analgesics; Animals; Biological Availability; Capsaicin; Chlorocebus aethiops; COS Cells; Hot Temperature; Humans; Hyperalgesia; In Vitro Techniques; Inflammation; Microsomes, Liver; Naphthyridines; Pain; Pyrazines; Pyridines; Pyrimidines; Quinazolines; Quinolines; Rats; Structure-Activity Relationship; TRPV Cation Channels | 2010 |
Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation.
Topics: Animals; Antineoplastic Agents; Atropine; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Cells, Cultured; Chromatography, High Pressure Liquid; Cisplatin; Cricetinae; Cricetulus; Dipeptides; Disease Models, Animal; Drug Interactions; Ganglia, Spinal; Gene Expression Regulation; Guinea Pigs; Hyperalgesia; Mice; Mice, Inbred C57BL; Mice, Knockout; Organoplatinum Compounds; Oxaliplatin; Pain Measurement; Piperazines; Pulmonary Artery; Quinazolines; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensory Receptor Cells; Spectrometry, Mass, Electrospray Ionization; Superoxides; Tissue Culture Techniques; Transient Receptor Potential Channels; TRPA1 Cation Channel | 2011 |
Trigeminal nerve injury ErbB3/ErbB2 promotes mechanical hypersensitivity.
Topics: Animals; Blotting, Western; Disease Models, Animal; Hyperalgesia; Lapatinib; Male; Neuralgia; Pain Threshold; Protein Kinase Inhibitors; Quinazolines; Rats; Rats, Inbred F344; Receptor, ErbB-2; Receptor, ErbB-3; Trigeminal Nerve Injuries; Vibrissae | 2012 |
Differential effects of calcitonin gene-related peptide receptor blockade by olcegepant on mechanical allodynia induced by ligation of the infraorbital nerve vs the sciatic nerve in the rat.
Topics: Activating Transcription Factor 3; Animals; Biomarkers; Calcitonin Gene-Related Peptide Receptor Antagonists; Dipeptides; Hyperalgesia; Interleukin-6; Locomotion; Male; Maxillary Nerve; Neuralgia; Pain Measurement; Piperazines; Piperidines; Proto-Oncogene Proteins c-fos; Quinazolines; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptors, Calcitonin Gene-Related Peptide; RNA, Messenger; Rotarod Performance Test; Sciatic Nerve; Serotonin 5-HT1 Receptor Agonists; Tryptamines | 2012 |
Novel transient receptor potential vanilloid 1 receptor antagonists for the treatment of pain: structure-activity relationships for ureas with quinoline, isoquinoline, quinazoline, phthalazine, quinoxaline, and cinnoline moieties.
Topics: Abdominal Pain; Administration, Oral; Analgesics; Animals; Biological Availability; Calcium; Cells, Cultured; Disease Models, Animal; Heterocyclic Compounds, 2-Ring; Humans; Hyperalgesia; Isoquinolines; Models, Molecular; Pain; Quinazolines; Quinolines; Rats; Receptors, Drug; Static Electricity; Structure-Activity Relationship; Urea | 2005 |
Antinociceptive activity of the selective iNOS inhibitor AR-C102222 in rodent models of inflammatory, neuropathic and post-operative pain.
Topics: Animals; Disease Models, Animal; Hyperalgesia; Inflammation; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Mononeuropathies; Nitric Oxide Synthase; Pain; Quinazolines; Rats; Rats, Sprague-Dawley | 2006 |
Increased calcitonin gene-related peptide in neuroma and invading macrophages is involved in the up-regulation of interleukin-6 and thermal hyperalgesia in a rat model of mononeuropathy.
Topics: Animals; Blotting, Western; Calcitonin Gene-Related Peptide; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Ectodysplasins; Enzyme-Linked Immunosorbent Assay; Hyperalgesia; Immunohistochemistry; In Vitro Techniques; Interleukin-6; Macrophages; Male; Membrane Proteins; Neuroma; Pain Measurement; Piperazines; Quinazolines; Rats; Rats, Sprague-Dawley; Reaction Time; Sciatic Neuropathy; Tumor Necrosis Factors; Up-Regulation | 2006 |