quinacrine has been researched along with Turner Syndrome in 13 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Turner Syndrome: A syndrome of defective gonadal development in phenotypic females associated with the karyotype 45,X (or 45,XO). Patients generally are of short stature with undifferentiated GONADS (streak gonads), SEXUAL INFANTILISM, HYPOGONADISM, webbing of the neck, cubitus valgus, elevated GONADOTROPINS, decreased ESTRADIOL level in blood, and CONGENITAL HEART DEFECTS. NOONAN SYNDROME (also called Pseudo-Turner Syndrome and Male Turner Syndrome) resembles this disorder; however, it occurs in males and females with a normal karyotype and is inherited as an autosomal dominant.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A patients with seizures, Von Willebrand disease, and symptoms of Turner syndrome was a chromosomal mosaic." | 1.26 | Structure and Barr body formation of an Xp + chromosome with two inactivation centers. ( Daly, RF; Patau, K; Sarto, GE; Therman, E, 1977) |
| "She is the sixth reported monosomy X patient to achieve pregnancy." | 1.26 | Pregnancy and the Turner syndrome. ( Bennett, S; King, CR; Magenis, E, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hayek, A | 1 |
| Yunis, E | 1 |
| Kulikov, RI | 1 |
| Mashkova, MV | 1 |
| Verlinskaia, DK | 1 |
| Bondarev, GN | 1 |
| Daly, RF | 1 |
| Patau, K | 1 |
| Therman, E | 1 |
| Sarto, GE | 1 |
| Hsu, LY | 1 |
| Paciuc, S | 1 |
| David, K | 1 |
| Cristian, S | 1 |
| Moloshok, R | 1 |
| Hirschhorn, K | 1 |
| King, CR | 1 |
| Magenis, E | 1 |
| Bennett, S | 1 |
| Coco, R | 1 |
| Bergada, C | 1 |
| Paulson, JD | 1 |
| Keller, DW | 1 |
| Muhlendorf, K | 1 |
| Eatherly, C | 1 |
| Distèche, C | 1 |
| Hagemeijer, A | 1 |
| Frederic, J | 1 |
| Progneaux, D | 1 |
| De la Chapelle, A | 1 |
| Stenstrand, K | 1 |
| Bühler, EM | 1 |
| Bühler, UK | 1 |
| Tsuchimoto, T | 1 |
| Stalder, GR | 1 |
| Breg, WR | 1 |
| Caspersson, T | 1 |
| Lindsten, J | 1 |
| Zech, L | 1 |
| Mende, S | 1 |
| Alonso, A | 1 |
13 other studies available for quinacrine and Turner Syndrome
| Article | Year |
|---|---|
Dicentric Y chromosome in mixed gonadal dysgenesis.
Topics: Adolescent; Chromosomes; Disorders of Sex Development; Dysgerminoma; Female; Humans; Karyotyping; Ly | 1975 |
[Identification of several chromosome aberrations in man by the fluorescent method using quinacrine yprite].
Topics: Adolescent; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Cytodiagnosis; Disorders | 1976 |
Structure and Barr body formation of an Xp + chromosome with two inactivation centers.
Topics: Adolescent; Female; Humans; Mosaicism; Quinacrine; Seizures; Sex Chromatin; Sex Chromosome Aberratio | 1977 |
Number of C-bands of human isochromosome Xqi and relation to 45,X mosaicism.
Topics: Azure Stains; Chromosome Aberrations; Female; Humans; Karyotyping; Mosaicism; Quinacrine; Sex Chromo | 1978 |
Pregnancy and the Turner syndrome.
Topics: Adult; Chromosome Banding; Congenital Abnormalities; Female; Humans; Infant, Newborn; Karyotyping; M | 1978 |
Cytogenetic findings in 125 patients with Turner's syndrome and abnormal karyotypes.
Topics: Acridines; Azure Stains; Bromodeoxyuridine; Chromosome Aberrations; Female; Humans; Karyotyping; Mat | 1977 |
A rapid screening technic for detection of Y chromosomes.
Topics: Amenorrhea; Cytogenetics; Female; Fluorescent Dyes; Humans; Karyotyping; Leukocytes; Male; Methods; | 1976 |
An abnormal large human chromosome identified as an end-to-end fusion of two X's by combined results of the new banding techniques and microdensitometry.
Topics: Abnormalities, Multiple; Adolescent; Blood; Chromosome Aberrations; Chromosome Disorders; Chromosome | 1972 |
Dicentric human X chromosomes.
Topics: Chromosome Aberrations; Female; Fluorescent Dyes; Heterochromatin; Humans; Karyotyping; Lymphocytes; | 1974 |
Non-fluorescent Y-chromosome.
Topics: Adolescent; Autoradiography; Body Height; Body Weight; Child; Chromosome Aberrations; Chromosomes, H | 1974 |
Updating advances in cytogenetics. Applications of the new chromosome banding methods.
Topics: Chromosome Aberrations; Chromosome Disorders; Chromosome Inversion; Chromosomes; Chromosomes, Human, | 1974 |
The nature of structural X chromosome aberrations in Turner's syndrome as revealed by quinacrine mustard fluorescence analysis.
Topics: Chromatids; Chromosome Aberrations; Chromosomes, Human, 1-3; Chromosomes, Human, 13-15; Chromosomes, | 1970 |
[Determination of male nuclear sex in human blood cells].
Topics: Adult; Eosinophils; Female; Humans; Karyotyping; Leukocytes; Lymphocytes; Male; Microscopy, Fluoresc | 1971 |