quinacrine has been researched along with Retinal Diseases in 6 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Retinal Diseases: Diseases involving the RETINA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Many of these reviews, while generally excellent, have propagated some apparent misconceptions by disregarding or de-emphasizing data suggesting that irreversible retinal toxicity due to antimalarials can be easily avoided by judicious daily dosage and regular ophthalmologic follow-up." | 2.36 | Antimalarials and ophthalmologic safety. ( Olansky, AJ, 1982) |
| "Hydroxychloroquine (HCQ) was used by 168 respondents, chloroquine (CQ) by 66, and mepacrine by 89 (only 111 always chose one of these)." | 1.29 | Ocular toxicity of antimalarials in dermatology: a survey of current practice. ( Cox, NH; Paterson, WD, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Browning, DJ | 1 |
| Lanham, JG | 1 |
| Hughes, GR | 1 |
| Olansky, AJ | 1 |
| Cox, NH | 1 |
| Paterson, WD | 1 |
| Dubois, EL | 1 |
| Brown, RK | 1 |
3 reviews available for quinacrine and Retinal Diseases
| Article | Year |
|---|---|
Antimalarial therapy in SLE.
Topics: Antimalarials; Binding Sites; Chloroquine; Corneal Diseases; Dose-Response Relationship, Drug; Femal | 1982 |
Antimalarials and ophthalmologic safety.
Topics: Antimalarials; Arthritis, Rheumatoid; Chloroquine; Humans; Hydroxychloroquine; Lupus Erythematosus, | 1982 |
Antimalarials in the management of discoid and systemic lupus erythematosus.
Topics: Animals; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Humans; Lupus Erythematosus, | 1978 |
3 other studies available for quinacrine and Retinal Diseases
| Article | Year |
|---|---|
Bull's-eye maculopathy associated with quinacrine therapy for malaria.
Topics: Antimalarials; Electroretinography; Fluorescein Angiography; Humans; Malaria, Vivax; Male; Middle Ag | 2004 |
Ocular toxicity of antimalarials in dermatology: a survey of current practice.
Topics: Antimalarials; Dermatology; Drug Administration Schedule; Humans; Hydroxychloroquine; Quinacrine; Re | 1994 |
Discoid lupus erythematosus.
Topics: Adult; Antimalarials; Chloroquine; Color Vision Defects; Female; Humans; Hydroxychloroquine; Lupus E | 1972 |