quinacrine has been researched along with Recrudescence in 20 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
| Excerpt | Relevance | Reference |
|---|---|---|
| "From 1982 to 1990, 27 patients with recurrent pneumothorax or persistent air leak (28 episodes) underwent pleurodesis with intrapleural administration of quinacrine, according to a standardized scheme." | 7.68 | Intrapleural quinacrine instillation for recurrent pneumothorax or persistent air leak. ( Derom, A; Derom, E; Derom, F; Eeckhout, C; Janzing, HM; Rosseel, MT, 1993) |
| "We used intrapleural instillation of quinacrine hydrochloride in 20 patients (Group A) with recurrent spontaneous pneumothorax (one bilateral) and compared their clinical course with 19 patients who underwent thoracotomy and scarification or pleurectomy (Group B) and 63 patients treated by tube thoracostomy alone (Group C)." | 7.66 | Intrapleural instillation of quinacrine for treatment of recurrent spontaneous pneumothorax. ( Derrick, JR; Larrieu, AJ; O'Neill, MJ; Tyers, GF; Williams, EH, 1979) |
| "A total of 121 pleurodeses using instillations of quinacrine (mepacrine) in patients with recurrent pleural effusion were performed." | 7.66 | Treatment of recurrent pleural effusion by pleurodesis with quinacrine. Comparison between instillation by repeated thoracenteses and by tube drainage. ( Korsgaard, R; Simonsson, BG; Stiksa, G, 1979) |
| " A dosage of 15-25 mg/kg a day for 5 days is recommended." | 6.65 | Giardiasis in infancy and childhood: a prospective study of 160 cases with comparison of quinacrine (Atabrine) and metronidazole (Flagyl). ( Kavousi, S, 1979) |
| "Quinacrine is an older antimalarial drug that remains in use for a variety of illnesses including treatment-resistant giardiasis." | 4.02 | A Case of Quinacrine-induced Psychosis: Case Report. ( Patel, A; Pedapudi, A; Stewart, J, 2021) |
| "From 1982 to 1990, 27 patients with recurrent pneumothorax or persistent air leak (28 episodes) underwent pleurodesis with intrapleural administration of quinacrine, according to a standardized scheme." | 3.68 | Intrapleural quinacrine instillation for recurrent pneumothorax or persistent air leak. ( Derom, A; Derom, E; Derom, F; Eeckhout, C; Janzing, HM; Rosseel, MT, 1993) |
| "We used intrapleural instillation of quinacrine hydrochloride in 20 patients (Group A) with recurrent spontaneous pneumothorax (one bilateral) and compared their clinical course with 19 patients who underwent thoracotomy and scarification or pleurectomy (Group B) and 63 patients treated by tube thoracostomy alone (Group C)." | 3.66 | Intrapleural instillation of quinacrine for treatment of recurrent spontaneous pneumothorax. ( Derrick, JR; Larrieu, AJ; O'Neill, MJ; Tyers, GF; Williams, EH, 1979) |
| "A total of 121 pleurodeses using instillations of quinacrine (mepacrine) in patients with recurrent pleural effusion were performed." | 3.66 | Treatment of recurrent pleural effusion by pleurodesis with quinacrine. Comparison between instillation by repeated thoracenteses and by tube drainage. ( Korsgaard, R; Simonsson, BG; Stiksa, G, 1979) |
| " A dosage of 15-25 mg/kg a day for 5 days is recommended." | 2.65 | Giardiasis in infancy and childhood: a prospective study of 160 cases with comparison of quinacrine (Atabrine) and metronidazole (Flagyl). ( Kavousi, S, 1979) |
| "Pleural effusion secondary to breast cancer is a locoregional manifestation." | 1.29 | Pleural effusion in breast cancer: a review of the Nottingham experience. ( Banerjee, AK; Blamey, RW; Robertson, JF; Willetts, I, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (80.00) | 18.7374 |
| 1990's | 3 (15.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pedapudi, A | 1 |
| Stewart, J | 1 |
| Patel, A | 1 |
| DOBROTVORSKAIA, NV | 1 |
| BAKER, BM | 1 |
| PLATT, D | 1 |
| CHOWDHURY, MZ | 1 |
| BROWN, M | 1 |
| RENNIE, JL | 1 |
| CHRISTIANSEN, JV | 1 |
| NIELSEN, JP | 1 |
| GELLHORN, A | 1 |
| ZAIDENWEBER, J | 1 |
| ULTMANN, J | 1 |
| HIRSCHBERG, E | 1 |
| McLoud, TC | 1 |
| Isler, R | 1 |
| Head, J | 1 |
| Koldsland, S | 1 |
| Svennevig, JL | 1 |
| Lehne, G | 1 |
| Johnson, E | 1 |
| Banerjee, AK | 1 |
| Willetts, I | 1 |
| Robertson, JF | 1 |
| Blamey, RW | 1 |
| Janzing, HM | 1 |
| Derom, A | 1 |
| Derom, E | 1 |
| Eeckhout, C | 1 |
| Derom, F | 1 |
| Rosseel, MT | 1 |
| Kavousi, S | 1 |
| Larrieu, AJ | 1 |
| Tyers, GF | 1 |
| Williams, EH | 1 |
| O'Neill, MJ | 1 |
| Derrick, JR | 1 |
| Stiksa, G | 1 |
| Korsgaard, R | 1 |
| Simonsson, BG | 1 |
| Blechman, MG | 1 |
| Leibowitz, A | 1 |
| Melon, V | 1 |
| Germaud, P | 1 |
| David, A | 1 |
| Stiles, MA | 1 |
| Kretchman, LA | 1 |
| Cattaneo, SM | 1 |
| Sirak, HD | 1 |
| Klassen, KP | 1 |
| Kattwinkel, J | 1 |
| Taussig, LM | 1 |
| McIntosh, CL | 1 |
| di Sant'Agnese, PA | 1 |
| Wood, RE | 1 |
| Bruce-Chwatt, LJ | 1 |
2 trials available for quinacrine and Recrudescence
| Article | Year |
|---|---|
Chemical pleurodesis in malignant pleural effusions: a randomised prospective study of mepacrine versus bleomycin.
Topics: Adult; Aged; Aged, 80 and over; Bleomycin; Drainage; Female; Humans; Male; Middle Aged; Pleural Effu | 1993 |
Giardiasis in infancy and childhood: a prospective study of 160 cases with comparison of quinacrine (Atabrine) and metronidazole (Flagyl).
Topics: Adolescent; Child; Child, Preschool; Feces; Female; Follow-Up Studies; Giardiasis; Humans; Infant; I | 1979 |
18 other studies available for quinacrine and Recrudescence
| Article | Year |
|---|---|
A Case of Quinacrine-induced Psychosis: Case Report.
Topics: Antimalarials; Giardiasis; Humans; Psychotic Disorders; Quinacrine; Recurrence | 2021 |
[Clinical aspects and relapse of leishmaniasis following acrichine therapy].
Topics: Chronic Disease; Leishmaniasis; Quinacrine; Recurrence | 1948 |
Vivax relapse rates following continued atabrine suppressive medication; observations on malaria in an infantry regiment.
Topics: Chronic Disease; Humans; Malaria; Malaria, Vivax; Quinacrine; Recurrence | 1947 |
Mepacrine and the relapse-rate of malaria.
Topics: Chronic Disease; Malaria; Quinacrine; Recurrence | 1946 |
Mepacrine metabolism in recurring benign tertian malaria.
Topics: Malaria; Malaria, Vivax; Quinacrine; Recurrence | 1946 |
Treatment of lupus erythematosus with mepacrine; results and relapses during a long observation.
Topics: Chronic Disease; Lupus Erythematosus, Systemic; Quinacrine; Recurrence | 1956 |
The use of atabrine (quinacrine) in the control of recurrent neoplastic effusions. A preliminary report.
Topics: Exudates and Transudates; Humans; Neoplasms; Quinacrine; Recurrence | 1961 |
The radiologic appearance of chemical pleurodesis.
Topics: Adolescent; Adult; Aged; Drug Therapy, Combination; Female; Humans; Infusions, Parenteral; Male; Mec | 1980 |
Pleural effusion in breast cancer: a review of the Nottingham experience.
Topics: Adult; Aged; Breast Neoplasms; Chest Tubes; Female; Humans; Instillation, Drug; Middle Aged; Pleural | 1994 |
Intrapleural quinacrine instillation for recurrent pneumothorax or persistent air leak.
Topics: Adult; Aged; Air; Female; Humans; Male; Middle Aged; Pleura; Pneumothorax; Quinacrine; Recurrence; R | 1993 |
Intrapleural instillation of quinacrine for treatment of recurrent spontaneous pneumothorax.
Topics: Adolescent; Adult; Aged; Child; Female; Follow-Up Studies; Hemorrhage; Humans; Intubation; Male; Mid | 1979 |
Treatment of recurrent pleural effusion by pleurodesis with quinacrine. Comparison between instillation by repeated thoracenteses and by tube drainage.
Topics: Drainage; Humans; Pleural Effusion; Pleural Neoplasms; Postoperative Complications; Quality of Life; | 1979 |
Resistant giardiasis secondary to duodenal diverticula. Case report.
Topics: Adult; Diarrhea; Diverticulum; Duodenal Diseases; Giardiasis; Humans; Male; Quinacrine; Recurrence | 1975 |
[Pneumothorax and cystic fibrosis. Intrapleural instillation of Quinacrine in 2 cases of recurrent pneumothorax].
Topics: Adolescent; Cystic Fibrosis; Humans; Instillation, Drug; Male; Pneumothorax; Quinacrine; Recurrence | 1987 |
Giardiasis and the adult traveler.
Topics: Adult; Diarrhea; Feces; Female; Giardia; Giardiasis; Humans; Metronidazole; Middle Aged; Quinacrine; | 1974 |
Recurrent spontaneous pneumothorax in the high-risk patient. Management with intrapleural quinacrine.
Topics: Adolescent; Autopsy; Child; Cystic Fibrosis; Follow-Up Studies; Humans; Injections; Male; Marfan Syn | 1973 |
Intrapleural instillation of quinacrine for recurrent pneumothorax. Use in a patient with cystic fibrosis.
Topics: Adult; Autopsy; Cystic Fibrosis; Follow-Up Studies; Humans; Male; Methods; Pleura; Pleural Diseases; | 1973 |
The role of drugs in a malaria program.
Topics: Amodiaquine; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Humans; Malaria; Primaqui | 1972 |