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quinacrine and Pneumothorax

quinacrine has been researched along with Pneumothorax in 16 studies

Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.

Pneumothorax: An accumulation of air or gas in the PLEURAL CAVITY, which may occur spontaneously or as a result of trauma or a pathological process. The gas may also be introduced deliberately during PNEUMOTHORAX, ARTIFICIAL.

Research Excerpts

ExcerptRelevanceReference
"From 1982 to 1990, 27 patients with recurrent pneumothorax or persistent air leak (28 episodes) underwent pleurodesis with intrapleural administration of quinacrine, according to a standardized scheme."7.68Intrapleural quinacrine instillation for recurrent pneumothorax or persistent air leak. ( Derom, A; Derom, E; Derom, F; Eeckhout, C; Janzing, HM; Rosseel, MT, 1993)
"We used intrapleural instillation of quinacrine hydrochloride in 20 patients (Group A) with recurrent spontaneous pneumothorax (one bilateral) and compared their clinical course with 19 patients who underwent thoracotomy and scarification or pleurectomy (Group B) and 63 patients treated by tube thoracostomy alone (Group C)."7.66Intrapleural instillation of quinacrine for treatment of recurrent spontaneous pneumothorax. ( Derrick, JR; Larrieu, AJ; O'Neill, MJ; Tyers, GF; Williams, EH, 1979)
"From 1982 to 1990, 27 patients with recurrent pneumothorax or persistent air leak (28 episodes) underwent pleurodesis with intrapleural administration of quinacrine, according to a standardized scheme."3.68Intrapleural quinacrine instillation for recurrent pneumothorax or persistent air leak. ( Derom, A; Derom, E; Derom, F; Eeckhout, C; Janzing, HM; Rosseel, MT, 1993)
"Intrapleural instillation of quinacrine HC1 (Atabrine) was used to treat spontaneous pneumothorax in 2 young men, aged 26 and 36 years, respectively, with advanced pulmonary disease due to cystic fibrosis."3.68[Pneumothorax in cystic fibrosis: intrapleural instillation of Atabrine]. ( Blau, H; Rosenman, Y; Szeinberg, A; Yahav, J; Yancu, Y; Zack, J, 1991)
"We used intrapleural instillation of quinacrine hydrochloride in 20 patients (Group A) with recurrent spontaneous pneumothorax (one bilateral) and compared their clinical course with 19 patients who underwent thoracotomy and scarification or pleurectomy (Group B) and 63 patients treated by tube thoracostomy alone (Group C)."3.66Intrapleural instillation of quinacrine for treatment of recurrent spontaneous pneumothorax. ( Derrick, JR; Larrieu, AJ; O'Neill, MJ; Tyers, GF; Williams, EH, 1979)
"The primary treatment of pneumothorax should be partial pleurectomy."1.28Pneumothorax in cystic fibrosis: a 26-year experience. ( Spector, ML; Stern, RC, 1989)
"The various treatments of spontaneous pneumothorax in cystic fibrosis are examined over a 15-yr period."1.26Open thoracotomy and pleural abrasion in the treatment of spontaneous pneumothorax in cystic fibrosis. ( Leonard, AS; Rich, RH; Warwick, WJ, 1978)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199012 (75.00)18.7374
1990's4 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ovrum, E1
Pillgram-Larsen, J1
Fjeld, NB1
McLaughlin, FJ1
Matthews, WJ1
Strieder, DJ1
Khaw, KT1
Schuster, S1
Shwachman, H1
McLoud, TC1
Isler, R1
Head, J1
Lomaestro, BM1
Lesar, TS1
Kaslovsky, RA1
Janzing, HM1
Derom, A1
Derom, E1
Eeckhout, C1
Derom, F1
Rosseel, MT1
Johnson, LP1
Rivkin, SE1
Weber, EL1
Larrieu, AJ1
Tyers, GF1
Williams, EH1
O'Neill, MJ1
Derrick, JR1
Rich, RH1
Warwick, WJ1
Leonard, AS1
Jones, RE1
Giammona, ST1
Boe, J1
Florvaag, E1
Yancu, Y1
Szeinberg, A1
Rosenman, Y1
Blau, H1
Zack, J1
Yahav, J1
Aebersold, A1
Schaad, UB1
Spector, ML1
Stern, RC1
Melon, V1
Germaud, P1
David, A1
Cattaneo, SM1
Sirak, HD1
Klassen, KP1
Kattwinkel, J1
Taussig, LM1
McIntosh, CL1
di Sant'Agnese, PA1
Wood, RE1

Reviews

1 review available for quinacrine and Pneumothorax

ArticleYear
[Pneumothorax in cystic fibrosis].
    Schweizerische medizinische Wochenschrift, 1991, Feb-09, Volume: 121, Issue:6

    Topics: Adolescent; Chest Tubes; Child; Cystic Fibrosis; Female; Humans; Male; Pneumothorax; Prognosis; Quin

1991

Other Studies

15 other studies available for quinacrine and Pneumothorax

ArticleYear
[Chemical pleurodesis in complicated pneumothorax. A therapeutic alternative in elderly patients].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1984, Mar-20, Volume: 104, Issue:8

    Topics: Age Factors; Aged; Drainage; Female; Humans; Lung Diseases; Male; Pleura; Pneumothorax; Quinacrine

1984
Pneumothorax in cystic fibrosis: management and outcome.
    The Journal of pediatrics, 1982, Volume: 100, Issue:6

    Topics: Adolescent; Adult; Child; Child, Preschool; Cystic Fibrosis; Female; Humans; Intubation; Male; Pleur

1982
The radiologic appearance of chemical pleurodesis.
    Radiology, 1980, Volume: 135, Issue:2

    Topics: Adolescent; Adult; Aged; Drug Therapy, Combination; Female; Humans; Infusions, Parenteral; Male; Mec

1980
Pleurodesis with solution prepared from quinacrine hydrochloride tablets.
    Clinical pharmacy, 1993, Volume: 12, Issue:9

    Topics: Adult; Cystic Fibrosis; Humans; Male; Pleura; Pneumothorax; Quinacrine; Solutions; Tablets

1993
Intrapleural quinacrine instillation for recurrent pneumothorax or persistent air leak.
    The Annals of thoracic surgery, 1993, Volume: 55, Issue:2

    Topics: Adult; Aged; Air; Female; Humans; Male; Middle Aged; Pleura; Pneumothorax; Quinacrine; Recurrence; R

1993
Palliation in malignant pleural effusion.
    The American surgeon, 1975, Volume: 41, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Breast Neoplasms; Drainage; Female; Hodgkin Disease; Humans; Lung Neopl

1975
Intrapleural instillation of quinacrine for treatment of recurrent spontaneous pneumothorax.
    The Annals of thoracic surgery, 1979, Volume: 28, Issue:2

    Topics: Adolescent; Adult; Aged; Child; Female; Follow-Up Studies; Hemorrhage; Humans; Intubation; Male; Mid

1979
Open thoracotomy and pleural abrasion in the treatment of spontaneous pneumothorax in cystic fibrosis.
    Journal of pediatric surgery, 1978, Volume: 13, Issue:3

    Topics: Adolescent; Adult; Child; Child, Preschool; Cystic Fibrosis; Female; Humans; Intubation; Male; Metho

1978
Intrapleural injection of quinacrine for pneumothorax in a child with cystic fibrosis.
    American journal of diseases of children (1960), 1976, Volume: 130, Issue:7

    Topics: Carbenicillin; Child; Cystic Fibrosis; Gentamicins; Humans; Injections; Male; Mediastinal Emphysema;

1976
[Chemical pleurodesis induced by mepacrine chloride. An alternative in the treatment of malignant pleural effusions].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1976, Aug-20, Volume: 96, Issue:23

    Topics: Aged; Female; Humans; Male; Middle Aged; Pleural Diseases; Pleural Effusion; Pneumothorax; Quinacrin

1976
[Pneumothorax in cystic fibrosis: intrapleural instillation of Atabrine].
    Harefuah, 1991, Mar-01, Volume: 120, Issue:5

    Topics: Adult; Cystic Fibrosis; Humans; Male; Pleura; Pneumothorax; Quinacrine; Sclerotherapy

1991
Pneumothorax in cystic fibrosis: a 26-year experience.
    The Annals of thoracic surgery, 1989, Volume: 47, Issue:2

    Topics: Adolescent; Adult; Child; Cystic Fibrosis; Female; Humans; Male; Pleura; Pneumothorax; Quinacrine; S

1989
[Pneumothorax and cystic fibrosis. Intrapleural instillation of Quinacrine in 2 cases of recurrent pneumothorax].
    Archives francaises de pediatrie, 1987, Volume: 44, Issue:2

    Topics: Adolescent; Cystic Fibrosis; Humans; Instillation, Drug; Male; Pneumothorax; Quinacrine; Recurrence

1987
Recurrent spontaneous pneumothorax in the high-risk patient. Management with intrapleural quinacrine.
    The Journal of thoracic and cardiovascular surgery, 1973, Volume: 66, Issue:3

    Topics: Adolescent; Autopsy; Child; Cystic Fibrosis; Follow-Up Studies; Humans; Injections; Male; Marfan Syn

1973
Intrapleural instillation of quinacrine for recurrent pneumothorax. Use in a patient with cystic fibrosis.
    JAMA, 1973, Oct-29, Volume: 226, Issue:5

    Topics: Adult; Autopsy; Cystic Fibrosis; Follow-Up Studies; Humans; Male; Methods; Pleura; Pleural Diseases;

1973