quinacrine has been researched along with Ovine Diseases in 3 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Quinacrine was reported to have a marked in vitro antiprion action in mouse neuroblastoma cells." | 2.71 | A possible pharmacological explanation for quinacrine failure to treat prion diseases: pharmacokinetic investigations in a ovine model of scrapie. ( Andréoletti, O; Gayrard, V; Laroute, V; Picard-Hagen, N; Toutain, PL; Viguié, C, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| STEWARD, JS | 1 |
| Gayrard, V | 1 |
| Picard-Hagen, N | 1 |
| Viguié, C | 1 |
| Laroute, V | 1 |
| Andréoletti, O | 1 |
| Toutain, PL | 1 |
| Adetosoye, AI | 1 |
1 trial available for quinacrine and Ovine Diseases
| Article | Year |
|---|---|
A possible pharmacological explanation for quinacrine failure to treat prion diseases: pharmacokinetic investigations in a ovine model of scrapie.
Topics: Algorithms; Animals; Cell Line, Tumor; Culture Media; Extracellular Space; Female; Injections, Intra | 2005 |
2 other studies available for quinacrine and Ovine Diseases
| Article | Year |
|---|---|
The ineffectiveness of mepacrine in the treatment of coccidiosis of chickens, mice and sheep.
Topics: Animals; Chickens; Coccidiosis; Disease; Mice; Poultry; Quinacrine; Sheep; Sheep Diseases; Sheep, Do | 1952 |
Plasmid curing in Escherichia coli isolated from diarrhoeic lambs and from a clinically healthy kid.
Topics: Acriflavine; Aminoacridines; Animals; Anti-Bacterial Agents; Diarrhea; Escherichia coli; Goats; Nige | 1980 |