quinacrine has been researched along with Neurodegenerative Diseases in 2 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Neurodegenerative Diseases: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Spilman, P | 1 |
| Lessard, P | 1 |
| Sattavat, M | 1 |
| Bush, C | 1 |
| Tousseyn, T | 1 |
| Huang, EJ | 1 |
| Giles, K | 1 |
| Golde, T | 1 |
| Das, P | 1 |
| Fauq, A | 1 |
| Prusiner, SB | 1 |
| Dearmond, SJ | 1 |
| Ong, WY | 1 |
| Lu, XR | 1 |
| Horrocks, LA | 1 |
| Farooqui, AA | 1 |
| Garey, LJ | 1 |
2 other studies available for quinacrine and Neurodegenerative Diseases
| Article | Year |
|---|---|
A gamma-secretase inhibitor and quinacrine reduce prions and prevent dendritic degeneration in murine brains.
Topics: Administration, Oral; Alanine; Amyloid Precursor Protein Secretases; Animals; Azepines; Brain; Dendr | 2008 |
Induction of astrocytic cytoplasmic phospholipase A2 and neuronal death after intracerebroventricular carrageenan injection, and neuroprotective effects of quinacrine.
Topics: Animals; Astrocytes; Carrageenan; Cell Death; Disease Progression; Enzyme Induction; Gliosis; Inject | 2003 |