quinacrine has been researched along with Neoplasm Metastasis in 9 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Quinacrine is a repositioned drug with an anticancer activity but suffers a limited ability to reach tumor cells." | 1.62 | Undaria pinnatifida fucoidan nanoparticles loaded with quinacrine attenuate growth and metastasis of pancreatic cancer. ( Abdallah, OY; Bary, AA; Elnaggar, YSR; Etman, SM; Mehanna, RA, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Etman, SM | 1 |
| Mehanna, RA | 1 |
| Bary, AA | 1 |
| Elnaggar, YSR | 1 |
| Abdallah, OY | 1 |
| Bhateja, P | 1 |
| Dowlati, A | 1 |
| Sharma, N | 1 |
| Siddharth, S | 1 |
| Nayak, D | 1 |
| Nayak, A | 1 |
| Das, S | 1 |
| Kundu, CN | 1 |
| Borda, I | 1 |
| Krant, M | 1 |
| Morin, LJ | 1 |
| Loening, S | 1 |
| Austin, EH | 1 |
| Flye, MW | 1 |
| Bennett, A | 1 |
| Melhuish, PB | 1 |
| Patel, S | 1 |
| Randles, H | 1 |
| Stamford, IF | 1 |
| Inoue, S | 1 |
| Ravindranath, Y | 1 |
| Ottenbreit, MJ | 1 |
| Thompson, RI | 1 |
| Zuelzer, WW | 1 |
| Borja, ER | 1 |
| Pugh, RP | 1 |
1 review available for quinacrine and Neoplasm Metastasis
| Article | Year |
|---|---|
The treatment of recurrent malignant pleural effusion.
Topics: Drainage; Humans; Intubation; Neoplasm Metastasis; Neoplasms; Nitrogen Mustard Compounds; Pleura; Pl | 1979 |
1 trial available for quinacrine and Neoplasm Metastasis
| Article | Year |
|---|---|
Phase I study of the combination of quinacrine and erlotinib in patients with locally advanced or metastatic non small cell lung cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carc | 2018 |
7 other studies available for quinacrine and Neoplasm Metastasis
| Article | Year |
|---|---|
Undaria pinnatifida fucoidan nanoparticles loaded with quinacrine attenuate growth and metastasis of pancreatic cancer.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Humans; Male; Mice; Mice, I | 2021 |
ABT-888 and quinacrine induced apoptosis in metastatic breast cancer stem cells by inhibiting base excision repair via adenomatous polyposis coli.
Topics: Adenomatous Polyposis Coli Protein; Antineoplastic Agents; Apoptosis; Benzimidazoles; Cell Line, Tum | 2016 |
Convulsions following intrapleural administration of quinacrine hydrochloride.
Topics: Adult; Breast Neoplasms; Epilepsy; Female; Genital Neoplasms, Female; Humans; Middle Aged; Neoplasm | 1967 |
Malignant androblastoma (Sertoli cell tumor) of the testis. A case report with a review of the literature.
Topics: Cyclophosphamide; Dactinomycin; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pleu | 1975 |
Cancer in mice: effects of prednisolone or mepacrine alone and with cytotoxic drugs.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Female; Male; Mammary Neoplasms, Experimental; Melphalan; Met | 1987 |
Chromosomal analysis of metastatic retinoblastoma cells.
Topics: Bone Marrow Cells; Cerebrospinal Fluid; Child, Preschool; Chromosome Aberrations; Humans; Karyotypin | 1974 |
Single-dose quinacrine (atabrine) and thoracostomy in the control of pleural effusions in patients with neoplastic diseases.
Topics: Drainage; Fever; Hallucinations; Humans; Hypotension; Intubation; Nausea; Neoplasm Metastasis; Neopl | 1973 |