quinacrine has been researched along with Muscular Diseases in 3 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Muscular Diseases: Acquired, familial, and congenital disorders of SKELETAL MUSCLE and SMOOTH MUSCLE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Quinacrine is an inhibitor of phospholipase A(2), an enzyme thought to be involved in activity-related injury of skeletal muscles." | 1.32 | Attenuation of stretch-induced histopathologic changes of skeletal muscles by quinacrine. ( Stauber, WT; Willems, ME, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Willems, ME | 1 |
| Stauber, WT | 1 |
| SULLI, G | 1 |
| VARRONE, F | 1 |
| Drenckhahn, D | 1 |
| Lüllmann-Rauch, R | 1 |
1 review available for quinacrine and Muscular Diseases
| Article | Year |
|---|---|
[EXTRAMALARIAL THERAPUETIC APPLICATIONS OF ANTIMALARIAL DRUGS. 1. CLINICAL UTILIZATIONS].
Topics: Amodiaquine; Antimalarials; Chloroquine; Collagen Diseases; Dermatology; Drug Utilization; Epilepsy; | 1963 |
2 other studies available for quinacrine and Muscular Diseases
| Article | Year |
|---|---|
Attenuation of stretch-induced histopathologic changes of skeletal muscles by quinacrine.
Topics: Albumins; Animals; Desmin; Enzyme Inhibitors; Female; Fibrosis; Muscle Contraction; Muscle Fibers, S | 2003 |
Experimental myopathy induced by amphiphilic cationic compounds including several psychotropic drugs.
Topics: Amitriptyline; Animals; Chloroquine; Chlorphentermine; Chlorpromazine; Female; Imipramine; Iprindole | 1979 |