quinacrine has been researched along with Melanoma in 6 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
Excerpt | Relevance | Reference |
---|---|---|
"Malignant melanoma is one of the most aggressive and lethal skin cancer." | 5.91 | Combination of niclosamide and quinacrine inactivates Akt/HK2/Cyclin D1 axis mediated by glucose deprivation towards the inhibition of melanoma cell proliferation. ( Ding, C; Ge, X; Jiang, J; Li, S; Li, Y; Qiao, Y; Wang, D; Wang, M; Wang, Y; Zheng, X, 2023) |
" A study of spectra recorded from cultured Ehrlich ascites (EL2), and Harding Passey melanoma cells (HPM-67 and HPM-73 line) grown under comparable conditions, shows that free NAD(P)H predominates in HPM-67 and EL2, while this coenzyme is bound in HPM-73." | 3.66 | The effect of atebrine and an acridine analog (BCMA) on the coenzyme fluorescence spectra of cultured melanoma and Ehrlich ascites (EL2) cells. ( Kohen, C; Kohen, E; Leising, HB; Marty, A; Salmon, JM; Schachtschabel, DO; Thorell, B; Viallet, P, 1978) |
"Malignant melanoma is one of the most aggressive and lethal skin cancer." | 1.91 | Combination of niclosamide and quinacrine inactivates Akt/HK2/Cyclin D1 axis mediated by glucose deprivation towards the inhibition of melanoma cell proliferation. ( Ding, C; Ge, X; Jiang, J; Li, S; Li, Y; Qiao, Y; Wang, D; Wang, M; Wang, Y; Zheng, X, 2023) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (66.67) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (16.67) | 24.3611 |
2020's | 1 (16.67) | 2.80 |
Authors | Studies |
---|---|
Li, S | 1 |
Wang, D | 1 |
Zheng, X | 1 |
Li, Y | 1 |
Ding, C | 1 |
Wang, M | 1 |
Ge, X | 1 |
Jiang, J | 1 |
Qiao, Y | 1 |
Wang, Y | 1 |
López-Jornet, P | 1 |
Pons-Fuster, A | 1 |
Biller, H | 1 |
Schachtschabel, DO | 3 |
Leising, HB | 2 |
Pfab, R | 2 |
Hess, F | 1 |
Viallet, P | 1 |
Kohen, E | 1 |
Marty, A | 1 |
Salmon, JM | 1 |
Kohen, C | 1 |
Thorell, B | 1 |
Kern, HF | 1 |
Shaw, MW | 1 |
6 other studies available for quinacrine and Melanoma
Article | Year |
---|---|
Combination of niclosamide and quinacrine inactivates Akt/HK2/Cyclin D1 axis mediated by glucose deprivation towards the inhibition of melanoma cell proliferation.
Topics: Cell Line, Tumor; Cell Proliferation; Cyclin D1; Glucose; Humans; Melanoma; Niclosamide; Proto-Oncog | 2023 |
Pigmented oral mucosa due to quinacrine.
Topics: Antimalarials; Diagnosis, Differential; Female; Humans; Lupus Erythematosus, Cutaneous; Melanoma; Mi | 2011 |
[Influence of x-rays and quinacrine (atebrine) or chloroquine (resochine)--alone or in combination--on growth and melanin formation of Harding-Passey melanoma cells in monolayer culture].
Topics: Cell Survival; Cells, Cultured; Chloroquine; Dose-Response Relationship, Radiation; Melanins; Melano | 1982 |
The effect of atebrine and an acridine analog (BCMA) on the coenzyme fluorescence spectra of cultured melanoma and Ehrlich ascites (EL2) cells.
Topics: Acridines; Animals; Carcinoma, Ehrlich Tumor; Cell Division; Cell Line; DNA, Neoplasm; Melanoma; NAD | 1978 |
[Ultrastructural studies of the effect of x-rays and quinacrine (Atebrin) or chloroquine (Resochin)--alone or in combination--on Harding-Passey melanoma cells in monolayer culture].
Topics: Animals; Chloroquine; Combined Modality Therapy; In Vitro Techniques; Melanoma; Mice; Microscopy, El | 1985 |
Uses of banding techniques for the identification of human diseases of cytogenetic origin.
Topics: Burkitt Lymphoma; Chromosome Aberrations; Chromosome Disorders; Genetic Techniques; Humans; Leukemia | 1973 |