quinacrine has been researched along with Lupus Erythematosus, Discoid in 58 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Lupus Erythematosus, Discoid: A chronic form of cutaneous lupus erythematosus (LUPUS ERYTHEMATOSUS, CUTANEOUS) in which the skin lesions mimic those of the systemic form but in which systemic signs are rare. It is characterized by the presence of discoid skin plaques showing varying degrees of edema, erythema, scaliness, follicular plugging, and skin atrophy. Lesions are surrounded by an elevated erythematous border. The condition typically involves the face and scalp, but widespread dissemination may occur.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cutaneous lupus erythematosus has a variety of clinical presentations, but treatment is similar for the different forms." | 2.41 | Current treatment of cutaneous lupus erythematosus. ( Werth, V, 2001) |
| " Many of these reviews, while generally excellent, have propagated some apparent misconceptions by disregarding or de-emphasizing data suggesting that irreversible retinal toxicity due to antimalarials can be easily avoided by judicious daily dosage and regular ophthalmologic follow-up." | 2.36 | Antimalarials and ophthalmologic safety. ( Olansky, AJ, 1982) |
| "Methods Mepacrine was added to 46 systemic lupus erythematosus patients unresponsive to treatment with the following drug combinations: hydroxychloroquine + prednisone + immunosuppressive drugs ( n = 24), hydroxychloroquine + prednisone ( n = 16), hydroxychloroquine + prednisone + retinoids ( n = 2), hydroxychloroquine alone ( n = 1), hydroxychloroquine + one immunosuppressive drug ( n = 1), hydroxychloroquine + prednisone + one immunosuppressive drug + belimumab ( n = 1) or hydroxychloroquine + prednisone + belimumab ( n = 1)." | 1.48 | Combined mepacrine-hydroxychloroquine treatment in patients with systemic lupus erythematosus and refractory cutaneous and articular activity. ( Agesta, N; Martinez-Zapico, A; Ortego-Centeno, N; Porta, S; Ríos, R; Ruiz-Irastorza, G; Ugarte, A, 2018) |
| " After a 2-month course of treatment with hydroxychloroquine dosage of 200 mg per day and a break of 3 months between courses, we observed a complete remission." | 1.43 | Unilateral unique Lupus tumidus: pathogenetic mystery and diagnostic problem. ( Bakardzhiev, I; Chokoeva, AA; Krasnaliev, I; Lotti, T; Tana, C; Tchernev, G; Wollina, U, 2016) |
| "Drug-induced psychosis resulted from the administration of quinacrine hydrochloride at a dosage of 100 mg twice daily for the treatment of discoid lupus." | 1.27 | Antimalarial psychosis revisited. ( Evans, RL; Khalid, S; Kinney, JL, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 49 (84.48) | 18.7374 |
| 1990's | 2 (3.45) | 18.2507 |
| 2000's | 3 (5.17) | 29.6817 |
| 2010's | 4 (6.90) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ugarte, A | 1 |
| Porta, S | 1 |
| Ríos, R | 1 |
| Martinez-Zapico, A | 1 |
| Ortego-Centeno, N | 1 |
| Agesta, N | 1 |
| Ruiz-Irastorza, G | 1 |
| Winn, RT | 1 |
| Miller, JAL | 1 |
| Meggitt, SJ | 2 |
| Waas, RLV | 1 |
| Bakardzhiev, I | 1 |
| Chokoeva, AA | 1 |
| Krasnaliev, I | 1 |
| Tana, C | 1 |
| Wollina, U | 1 |
| Lotti, T | 1 |
| Tchernev, G | 1 |
| Lerman, MA | 1 |
| Karimbux, N | 1 |
| Guze, KA | 1 |
| Woo, SB | 1 |
| CRAMER, JA | 1 |
| LEWIS, GM | 1 |
| SAWICKY, HH | 1 |
| KANOF, NB | 1 |
| SILVERBERG, MG | 1 |
| BRAITMAN, M | 1 |
| KALISH, B | 1 |
| WELLS, GC | 3 |
| O'LEARY, PA | 1 |
| BRUNSTING, LA | 1 |
| KIERLAND, RR | 1 |
| ZAKON, SJ | 1 |
| BUCHANAN, RN | 2 |
| MILLER, F | 1 |
| PARMER, LG | 1 |
| SAWITSKY, A | 1 |
| FARBER, EM | 1 |
| DRIVER, IE | 1 |
| COLE, HN | 2 |
| CHIVINGTON, PV | 1 |
| DRIVER, JR | 1 |
| RHODES, BL | 1 |
| ALLENDE, MF | 1 |
| KENNEDY, CB | 1 |
| HENINGTON, VM | 1 |
| GARVIN, WH | 1 |
| BAHCALL, C | 1 |
| HELANEN, S | 1 |
| ROGERS, J | 1 |
| FINN, OA | 1 |
| DUBOIS, EL | 2 |
| BUCHANAN, R | 1 |
| KING, H | 1 |
| HAMILTON, CM | 1 |
| VILANOVA, X | 1 |
| RUST, S | 1 |
| CHRISTIANSEN, JV | 2 |
| REIN, CR | 1 |
| FLEISCHMAJER, R | 1 |
| GEORGIEV, G | 1 |
| BAZHDEKOV, B | 1 |
| TYE, MJ | 2 |
| ANSELL, HB | 2 |
| WOLF, M | 1 |
| APPEL, B | 2 |
| SCHIFF, B | 1 |
| ROBINSON, RC | 1 |
| SMITH, GC | 1 |
| WHITE, H | 1 |
| SHEARD, C | 1 |
| MARCIANO, MR | 1 |
| FREDRIKSSON, T | 1 |
| LODIN, A | 1 |
| ROSENGREN, S | 1 |
| TUFFANELLI, D | 1 |
| ABRAHAM, RK | 1 |
| DUBOIS, EI | 1 |
| HASERICK, JR | 1 |
| BORC, K | 1 |
| RAAB, W | 1 |
| RUTLEDGE, WU | 1 |
| BETTLEY, FR | 1 |
| FAST, K | 1 |
| WESTERBERG, P | 1 |
| Evans, RL | 1 |
| Khalid, S | 1 |
| Kinney, JL | 1 |
| Lanham, JG | 1 |
| Hughes, GR | 1 |
| Olansky, AJ | 1 |
| Lipsker, D | 1 |
| Piette, JC | 1 |
| Cacoub, P | 1 |
| Godeau, P | 1 |
| Frances, C | 1 |
| Feldmann, R | 1 |
| Salomon, D | 1 |
| Saurat, JH | 1 |
| von Schmiedeberg, S | 1 |
| Rönnau, AC | 1 |
| Schuppe, HC | 1 |
| Specker, C | 1 |
| Ruzicka, T | 1 |
| Lehmann, P | 1 |
| Werth, V | 2 |
| Breathnach, SM | 1 |
| Humphreys, F | 1 |
| Marks, JM | 1 |
| Walker, SJ | 1 |
| Montgomery, S | 1 |
| Brearley, R | 1 |
| Galloway, A | 1 |
| Franks, A | 1 |
| Clark, SK | 1 |
| Brown, RK | 1 |
| Freeman, RG | 1 |
| Knox, JM | 1 |
| Owens, DW | 1 |
| Winkelmann, RK | 1 |
| Biro, L | 1 |
| Leone, N | 1 |
5 reviews available for quinacrine and Lupus Erythematosus, Discoid
| Article | Year |
|---|---|
[ANTIMALARIALS IN THE TREATMENT OF SKIN DISEASES].
Topics: Adrenal Cortex Hormones; Antimalarials; Chloroquine; Dermatology; Humans; Lupus Erythematosus, Disco | 1963 |
Antimalarial therapy in SLE.
Topics: Antimalarials; Binding Sites; Chloroquine; Corneal Diseases; Dose-Response Relationship, Drug; Femal | 1982 |
Antimalarials and ophthalmologic safety.
Topics: Antimalarials; Arthritis, Rheumatoid; Chloroquine; Humans; Hydroxychloroquine; Lupus Erythematosus, | 1982 |
Current treatment of cutaneous lupus erythematosus.
Topics: Administration, Topical; Adrenal Cortex Hormones; Adult; Antimalarials; Aspirin; Diagnosis, Differen | 2001 |
Antimalarials in the management of discoid and systemic lupus erythematosus.
Topics: Animals; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Humans; Lupus Erythematosus, | 1978 |
53 other studies available for quinacrine and Lupus Erythematosus, Discoid
| Article | Year |
|---|---|
Combined mepacrine-hydroxychloroquine treatment in patients with systemic lupus erythematosus and refractory cutaneous and articular activity.
Topics: Adult; Antimalarials; Drug Therapy, Combination; Female; Humans; Hydroxychloroquine; Immunosuppressi | 2018 |
Is chloroquine neuromyotoxicity in a patient with refractory discoid lupus erythematosus potentiated by concomitant use of mepacrine?
Topics: Antimalarials; Chloroquine; Drug Therapy, Combination; Extremities; Female; Humans; Lupus Erythemato | 2018 |
Mepacrine-induced interstitial lung disease in discoid lupus erythematosus?
Topics: Adult; Diagnosis, Differential; Female; Fibrosis; Glucocorticoids; Humans; Lung; Lung Diseases, Inte | 2018 |
Unilateral unique Lupus tumidus: pathogenetic mystery and diagnostic problem.
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Biopsy; Chloroquine; Combined Modality Therapy; Dapson | 2016 |
Pigmentation of the hard palate.
Topics: Antimalarials; Diagnosis, Differential; Female; Humans; Lupus Erythematosus, Discoid; Melanosis; Mid | 2009 |
Atabrine in the treatment of discoid lupus erythematosus.
Topics: Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Quinacrine | 1952 |
Therapeutic assays of the Skin and Cancer Unit of the New York University Hospital. Assay VII-Quinacrine hydrochloride (atabrine hydrochloride) for chronic discoid lupus erythematosus.
Topics: Hospitals, University; Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Neoplasms; New Y | 1952 |
Treatment of chronic discoid lupus erythematosus with atabrine.
Topics: Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Quinacrine | 1952 |
Quinacrine (atabrine) hydrochloride in treatment of discoid lupus erythematosus.
Topics: Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Quinacrine; Salts | 1953 |
Chronic discoid lupus erythematosis treated with quinacrine hydrochloride (atabrine dihydrochloride).
Topics: Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Quinacrine | 1953 |
Chronic discoid lupus erythematosus treated with quinacrine hydrochloride (atabrine dihydrochloride).
Topics: Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Quinacrine | 1953 |
The treatment of discoid lupus erythematosus.
Topics: Lupus Erythematosus, Discoid; Quinacrine | 1953 |
Atabrine therapy in discoid lupus erythematosus.
Topics: Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Quinacrine | 1953 |
Fatal aplastic anemia following quinacrine therapy in chronic discoid lupus erythematosus.
Topics: Anemia; Anemia, Aplastic; Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Quinacrine | 1953 |
Atabrine and chloroquine in the treatment of chronic discoid lupus erythematosus.
Topics: Chloroquine; Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Quinacrine | 1953 |
Treatment of chronic discoid lupus erythematosus with quinacrine.
Topics: Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Quinacrine | 1953 |
Treatment of chronic discoid lupus erythematosus with quinacrine.
Topics: Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Quinacrine | 1954 |
Treatment of chronic discoid lupus erythematosus with atabrine.
Topics: Humans; Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Quinacrine | 1954 |
Treatment of chronic discoid lupus erythematosus with atabrine.
Topics: Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Quinacrine | 1954 |
Synthetic antimalarial drugs in chronic discoid lupus erythematosus and light eruptions.
Topics: Antimalarials; Chloroquine; Light; Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Quin | 1954 |
Quinacrine (atabrine) in treatment of systemic and discoid lupus erythematosus.
Topics: Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Quinacrine | 1954 |
Quinacrine in discoid lupus erythematosus; the present day status.
Topics: Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Quinacrine | 1954 |
[Atebrine and chloroquine/resochin therapy of lupus erythematous and dermatoses due to photosensitivity].
Topics: Chloroquine; Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Quinacrine; Skin Diseases | 1954 |
[Electrophoretic studies on atabrine therapy of chronic discoid lupus erythematosus].
Topics: Electrophoresis; Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Quinacrine | 1955 |
Treatment of lupus erythematosus with chloroquine; therapeutic results and a comparison of the value of chloroquine and mepacrine.
Topics: Chloroquine; Humans; Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Quinacrine | 1957 |
The treatment of lupus erythematosus and lymphocytic infiltration of the skin with A.P.A. 5533.
Topics: Chloroquine; Humans; Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Quinacrine; Skin; | 1957 |
[Chloroquine therapy of lupus erythematosus; comparative effectivity of chloroquine and mepacrine].
Topics: Chloroquine; Humans; Lupus Erythematosus, Discoid; Quinacrine | 1957 |
[Treatment of lupus erythematosus by local infiltrations of atabrine].
Topics: Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Quinacrine | 1957 |
Treatment of chronic lupus erythematosus: effectiveness of plaquenil and APA (Aralen 65 mg., plaquenil 50 mg., Atabrine 25 mg.) as compared with Aralen, with observations on side-reactions and toxicity; report and presentation of unusual cases.
Topics: Antimalarials; Chloroquine; Humans; Hydroxychloroquine; Lupus Erythematosus, Discoid; Lupus Erythema | 1958 |
Triquin in the treatment of discoid lupus erythematosus and light sensitive eruptions.
Topics: Chloroquine; Exanthema; Humans; Light; Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; | 1958 |
Lupus erythematosus treated with a combination of quinacrine, hydroxychloroquine and chloroquine.
Topics: Chloroquine; Humans; Hydroxychloroquine; Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic | 1959 |
The use of triquin in the treatment of discoid lupus erythematosus and some other skin conditions.
Topics: Chloroquine; Humans; Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Quinacrine; Skin D | 1959 |
Quinacrine in the treatment of discoid lupus erythematosus: a five year follow-up survey; results and evaluation.
Topics: Data Collection; Follow-Up Studies; Humans; Lupus Erythematosus, Discoid; Quinacrine | 1959 |
[Treatment of discoid lupus erythematosus, polymorphous photodermatosis and rosacea with Triquin--a combination of 3 anti-malarials].
Topics: Antimalarials; Chloroquine; Humans; Hydroxychloroquine; Lupus Erythematosus, Discoid; Lupus Erythema | 1962 |
PIGMENTATION FROM ANTIMALARIAL THERAPY. ITS POSSIBLE RELATIONSHIP TO THE OCULAR LESIONS.
Topics: Antimalarials; Arthritis; Arthritis, Rheumatoid; Chloroquine; Cornea; Eye; Eye Manifestations; Histo | 1963 |
LUPUS ERYTHEMATOSUS--A CLINICAL QUIZ. A SERIES OF DIAGNOSTIC AND THERAPEUTIC PROBLEMS.
Topics: Chloroquine; Diagnosis; Humans; Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Quinacr | 1963 |
[CHRONIC DISCOID ERYTHEMATOSUS (REPORT ON 69 CASES OVER A PERIOD OF 6 YEARS FROM THE VIEWPOINT OF OPTIMUM THERAPY)].
Topics: Antimalarials; Chloroquine; Humans; Hydroxychloroquine; Lupus Erythematosus, Discoid; Lupus Erythema | 1963 |
WHAT'S NEW AND WHAT'S TRUE OF WHAT'S NEW IN DERMATOLOGY.
Topics: Amodiaquine; Dermatology; Humans; Hydroxychloroquine; Keratoacanthoma; Lupus Erythematosus, Discoid; | 1964 |
CHILBLAIN LUPUS ERYTHEMATOSUS.
Topics: Chilblains; Chloroquine; Fluocinolone Acetonide; Frostbite; Humans; Hydroxychloroquine; Hypothyroidi | 1964 |
[Mepacrine in therapy of chronic discoid lupus erythematosus].
Topics: Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Quinacrine | 1955 |
Antimalarial psychosis revisited.
Topics: Female; Humans; Lupus Erythematosus, Discoid; Middle Aged; Psychoses, Substance-Induced; Quinacrine | 1984 |
Chloroquine-quinacrine association in resistant cutaneous lupus.
Topics: Adult; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Lupus Erythematosus, Cutaneo | 1995 |
The association of the two antimalarials chloroquine and quinacrine for treatment-resistant chronic and subacute cutaneous lupus erythematosus.
Topics: Adult; Aged; Chloroquine; Drug Combinations; Drug Tolerance; Female; Humans; Hydroxychloroquine; Lup | 1994 |
[Combination of antimalarial drugs mepacrine and chloroquine in therapy refractory cutaneous lupus erythematosus].
Topics: Adult; Antimalarials; Chloroquine; Drug Therapy, Combination; Facial Dermatoses; Female; Humans; Lup | 2000 |
Chilblain lupus erythematosus with response to chemical sympathectomy.
Topics: Adult; Chilblains; Frostbite; Humans; Lumbosacral Region; Lupus Erythematosus, Discoid; Male; Phenol | 1979 |
Mepacrine and pregnancy.
Topics: Female; Humans; Lupus Erythematosus, Discoid; Pregnancy; Pregnancy Complications; Quinacrine | 1988 |
A case of primary peritonitis possibly related to mepacrine.
Topics: Adult; Humans; Lupus Erythematosus, Discoid; Male; Peritonitis; Quinacrine | 1987 |
Treatment of discoid skin lesions with azathioprine.
Topics: Azathioprine; Female; Humans; Hydroxychloroquine; Lupus Erythematosus, Discoid; Quinacrine | 1986 |
Cutaneous lupus erythematosus. Recognition of its many forms.
Topics: Adrenal Cortex Hormones; Adult; Chloroquine; Diagnosis, Differential; Female; Humans; Hydroxychloroq | 1986 |
Discoid lupus erythematosus.
Topics: Adult; Antimalarials; Chloroquine; Color Vision Defects; Female; Humans; Hydroxychloroquine; Lupus E | 1972 |
Cutaneous lesions of lupus erythematosus induced by monochromatic light.
Topics: Acanthosis Nigricans; Edema; Erythema; Humans; Lupus Erythematosus, Discoid; Lupus Erythematosus, Sy | 1969 |
Chronic discoid lupus erythematosus in children.
Topics: Adolescent; Adult; Child; Chronic Disease; Cortisone; Fluocinolone Acetonide; Flurandrenolone; Human | 1968 |
Aplastic anemia induced by quinacrine.
Topics: Anemia, Aplastic; Arthritis, Rheumatoid; Female; Humans; Lupus Erythematosus, Discoid; Middle Aged; | 1965 |