quinacrine has been researched along with Leukemia P388 in 4 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Leukemia P388: An experimental lymphocytic leukemia originally induced in DBA/2 mice by painting with methylcholanthrene.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Finlay, GJ | 1 |
| Wilson, WR | 1 |
| Baguley, BC | 2 |
| Schneider, E | 1 |
| Darkin, SJ | 1 |
| Lawson, PA | 1 |
| Ching, LM | 1 |
| Ralph, RK | 1 |
| Inaba, M | 2 |
| Maruyama, E | 1 |
4 other studies available for quinacrine and Leukemia P388
| Article | Year |
|---|---|
Chemoprotection by 9-aminoacridine derivatives against the cytotoxicity of topoisomerase II-directed drugs.
Topics: Aminacrine; Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Colony-Forming Units Assay; I | 1989 |
Cell line selectivity and DNA breakage properties of the antitumour agent N-[2-(dimethylamino)ethyl]acridine-4-carboxamide: role of DNA topoisomerase II.
Topics: Acridines; Aminacrine; Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Cell Survival; DNA | 1988 |
Reversal of resistance to vincristine in P388 leukemia by various polycyclic clinical drugs, with a special emphasis on quinacrine.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Drug Resistance; Drug Synergis | 1988 |
[Studies on the mechanism of multidrug resistance].
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Dactinomycin; | 1987 |