quinacrine has been researched along with Leukemia L5178 in 2 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Leukemia L5178: An experimental lymphocytic leukemia of mice.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methyl methanesulfonate (MMS) was used as a positive control in these studies." | 1.26 | Comparative mutagenicity of 4 DNA-intercalating agents in L5178Y mouse lymphoma cells. ( Back, KC; Rogers, AM, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fioretti, MC | 1 |
| Bianchi, R | 1 |
| Romani, L | 1 |
| Bonmassar, E | 1 |
| Rogers, AM | 1 |
| Back, KC | 1 |
2 other studies available for quinacrine and Leukemia L5178
| Article | Year |
|---|---|
Drug-induced immunogenic changes of murine leukemia cells: dissociation of onset of resistance and emergence of novel immunogenicity.
Topics: Animals; Cell Line; Clone Cells; Dacarbazine; Drug Resistance; Immunity, Cellular; Leukemia L5178; L | 1983 |
Comparative mutagenicity of 4 DNA-intercalating agents in L5178Y mouse lymphoma cells.
Topics: Acridine Orange; Acridines; Animals; Cell Survival; Ethidium; Intercalating Agents; Leukemia L5178; | 1982 |